LOCUS       DAFLWZ010000001       106590 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000001 DAFLWZ010000000
VERSION     DAFLWZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.001"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1421)
                     /locus_tag="L1V38_000001"
     CDS             complement(<1..1421)
                     /locus_tag="L1V38_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1314587.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1673..2854
                     /locus_tag="L1V38_000002"
     CDS             1673..2854
                     /locus_tag="L1V38_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1314588.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2914..4542)
                     /gene="treC"
                     /locus_tag="L1V38_000003"
     CDS             complement(2914..4542)
                     /gene="treC"
                     /locus_tag="L1V38_000003"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBN1314589.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4993..7704)
                     /locus_tag="L1V38_000004"
     CDS             complement(4993..7704)
                     /locus_tag="L1V38_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314590.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7714..8415)
                     /locus_tag="L1V38_000005"
     CDS             complement(7714..8415)
                     /locus_tag="L1V38_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314591.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8601..9200
                     /locus_tag="L1V38_000006"
     CDS             8601..9200
                     /locus_tag="L1V38_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1314592.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9281..10294
                     /locus_tag="L1V38_000007"
     CDS             9281..10294
                     /locus_tag="L1V38_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1314593.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10402..11319
                     /gene="rbsK"
                     /locus_tag="L1V38_000008"
     CDS             10402..11319
                     /gene="rbsK"
                     /locus_tag="L1V38_000008"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBN1314594.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11347..11742
                     /gene="rbsD"
                     /locus_tag="L1V38_000009"
     CDS             11347..11742
                     /gene="rbsD"
                     /locus_tag="L1V38_000009"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBN1314595.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11742..13115
                     /locus_tag="L1V38_000010"
     CDS             11742..13115
                     /locus_tag="L1V38_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1314596.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13472..15616
                     /locus_tag="L1V38_000011"
     CDS             13472..15616
                     /locus_tag="L1V38_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1314597.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15668..16708)
                     /locus_tag="L1V38_000012"
     CDS             complement(15668..16708)
                     /locus_tag="L1V38_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1314598.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16985..18787)
                     /locus_tag="L1V38_000013"
     CDS             complement(16985..18787)
                     /locus_tag="L1V38_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314599.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18801..19553)
                     /locus_tag="L1V38_000014"
     CDS             complement(18801..19553)
                     /locus_tag="L1V38_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314600.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19562..19924)
                     /locus_tag="L1V38_000015"
     CDS             complement(19562..19924)
                     /locus_tag="L1V38_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1314601.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20100..20972)
                     /locus_tag="L1V38_000016"
     CDS             complement(20100..20972)
                     /locus_tag="L1V38_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1314602.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21023..21511)
                     /locus_tag="L1V38_000017"
     CDS             complement(21023..21511)
                     /locus_tag="L1V38_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1314603.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21649..22440)
                     /locus_tag="L1V38_000018"
     CDS             complement(21649..22440)
                     /locus_tag="L1V38_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBN1314604.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22495..23103)
                     /locus_tag="L1V38_000019"
     CDS             complement(22495..23103)
                     /locus_tag="L1V38_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBN1314605.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23096..23413)
                     /locus_tag="L1V38_000020"
     CDS             complement(23096..23413)
                     /locus_tag="L1V38_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1314606.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23569..24297)
                     /locus_tag="L1V38_000021"
     CDS             complement(23569..24297)
                     /locus_tag="L1V38_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBN1314607.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24456..25337
                     /locus_tag="L1V38_000022"
     CDS             24456..25337
                     /locus_tag="L1V38_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1314608.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25574..26617)
                     /locus_tag="L1V38_000023"
     CDS             complement(25574..26617)
                     /locus_tag="L1V38_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1314609.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26620..27288)
                     /locus_tag="L1V38_000024"
     CDS             complement(26620..27288)
                     /locus_tag="L1V38_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1314610.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27430..29766
                     /locus_tag="L1V38_000025"
     CDS             27430..29766
                     /locus_tag="L1V38_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1314611.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29881..30192)
                     /locus_tag="L1V38_000026"
     CDS             complement(29881..30192)
                     /locus_tag="L1V38_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314612.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30373..31848
                     /locus_tag="L1V38_000027"
     CDS             30373..31848
                     /locus_tag="L1V38_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBN1314613.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31895..32479
                     /locus_tag="L1V38_000028"
     CDS             31895..32479
                     /locus_tag="L1V38_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBN1314614.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32481..32864
                     /locus_tag="L1V38_000029"
     CDS             32481..32864
                     /locus_tag="L1V38_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBN1314615.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33181..33465)
                     /locus_tag="L1V38_000030"
     CDS             complement(33181..33465)
                     /locus_tag="L1V38_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBN1314616.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33817..34527)
                     /locus_tag="L1V38_000031"
     CDS             complement(33817..34527)
                     /locus_tag="L1V38_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBN1314617.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34524..35996)
                     /locus_tag="L1V38_000032"
     CDS             complement(34524..35996)
                     /locus_tag="L1V38_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1314618.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36134..36607
                     /locus_tag="L1V38_000033"
     CDS             36134..36607
                     /locus_tag="L1V38_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1314619.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36760..37311)
                     /locus_tag="L1V38_000034"
     CDS             complement(36760..37311)
                     /locus_tag="L1V38_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1314620.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37416..37946
                     /locus_tag="L1V38_000035"
     CDS             37416..37946
                     /locus_tag="L1V38_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBN1314621.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38429..38872)
                     /locus_tag="L1V38_000036"
     CDS             complement(38429..38872)
                     /locus_tag="L1V38_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1314622.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38888..40048)
                     /locus_tag="L1V38_000037"
     CDS             complement(38888..40048)
                     /locus_tag="L1V38_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1314623.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40555..42255
                     /locus_tag="L1V38_000038"
     CDS             40555..42255
                     /locus_tag="L1V38_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314624.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42357..43190)
                     /locus_tag="L1V38_000039"
     CDS             complement(42357..43190)
                     /locus_tag="L1V38_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBN1314625.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43494..45659)
                     /locus_tag="L1V38_000040"
     CDS             complement(43494..45659)
                     /locus_tag="L1V38_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1314626.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45919..48213
                     /locus_tag="L1V38_000041"
     CDS             45919..48213
                     /locus_tag="L1V38_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1314627.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48206..48871
                     /gene="pgmB"
                     /locus_tag="L1V38_000042"
     CDS             48206..48871
                     /gene="pgmB"
                     /locus_tag="L1V38_000042"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1314628.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48864..49871
                     /locus_tag="L1V38_000043"
     CDS             48864..49871
                     /locus_tag="L1V38_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1314629.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49893..50912
                     /locus_tag="L1V38_000044"
     CDS             49893..50912
                     /locus_tag="L1V38_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1314630.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51193..52560)
                     /gene="nhaC"
                     /locus_tag="L1V38_000045"
     CDS             complement(51193..52560)
                     /gene="nhaC"
                     /locus_tag="L1V38_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1314631.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52669..54090)
                     /locus_tag="L1V38_000046"
     CDS             complement(52669..54090)
                     /locus_tag="L1V38_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1314632.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54333..56210)
                     /gene="tdc"
                     /locus_tag="L1V38_000047"
     CDS             complement(54333..56210)
                     /gene="tdc"
                     /locus_tag="L1V38_000047"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1314633.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56501..57757)
                     /locus_tag="L1V38_000048"
     CDS             complement(56501..57757)
                     /locus_tag="L1V38_000048"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBN1314634.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57869..58074)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58337..59638
                     /locus_tag="L1V38_000049"
     CDS             58337..59638
                     /locus_tag="L1V38_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1314635.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59707..60306)
                     /locus_tag="L1V38_000050"
     CDS             complement(59707..60306)
                     /locus_tag="L1V38_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1314636.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60560..61441
                     /locus_tag="L1V38_000051"
     CDS             60560..61441
                     /locus_tag="L1V38_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314637.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61454..63064
                     /locus_tag="L1V38_000052"
     CDS             61454..63064
                     /locus_tag="L1V38_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBN1314638.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63141..63800)
                     /locus_tag="L1V38_000053"
     CDS             complement(63141..63800)
                     /locus_tag="L1V38_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1314639.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64083..64748)
                     /locus_tag="L1V38_000054"
     CDS             complement(64083..64748)
                     /locus_tag="L1V38_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBN1314640.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(64895..65500)
                     /gene="dhaL"
                     /locus_tag="L1V38_000055"
     CDS             complement(64895..65500)
                     /gene="dhaL"
                     /locus_tag="L1V38_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBN1314641.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(65528..66538)
                     /gene="dhaK"
                     /locus_tag="L1V38_000056"
     CDS             complement(65528..66538)
                     /gene="dhaK"
                     /locus_tag="L1V38_000056"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBN1314642.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(66513..66959)
                     /gene="dhaM"
                     /locus_tag="L1V38_000057"
     CDS             complement(66513..66959)
                     /gene="dhaM"
                     /locus_tag="L1V38_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBN1314643.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            67062..67382
                     /locus_tag="L1V38_000058"
     CDS             67062..67382
                     /locus_tag="L1V38_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBN1314644.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(67494..68363)
                     /locus_tag="L1V38_000059"
     CDS             complement(67494..68363)
                     /locus_tag="L1V38_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1314645.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(68459..69763)
                     /locus_tag="L1V38_000060"
     CDS             complement(68459..69763)
                     /locus_tag="L1V38_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1314646.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(69760..70269)
                     /locus_tag="L1V38_000061"
     CDS             complement(69760..70269)
                     /locus_tag="L1V38_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314647.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(70444..72579)
                     /locus_tag="L1V38_000062"
     CDS             complement(70444..72579)
                     /locus_tag="L1V38_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1314648.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(72662..74317)
                     /locus_tag="L1V38_000063"
     CDS             complement(72662..74317)
                     /locus_tag="L1V38_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1314649.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(74319..74633)
                     /locus_tag="L1V38_000064"
     CDS             complement(74319..74633)
                     /locus_tag="L1V38_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1314650.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            74803..75063
                     /locus_tag="L1V38_000065"
     CDS             74803..75063
                     /locus_tag="L1V38_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBN1314651.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            75077..75391
                     /locus_tag="L1V38_000066"
     CDS             75077..75391
                     /locus_tag="L1V38_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBN1314652.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(76121..76675)
                     /locus_tag="L1V38_000067"
     CDS             complement(76121..76675)
                     /locus_tag="L1V38_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBN1314653.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(76801..78730)
                     /locus_tag="L1V38_000068"
                     /pseudo
     CDS             complement(76801..78730)
                     /locus_tag="L1V38_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(79036..79752)
                     /locus_tag="L1V38_000069"
     CDS             complement(79036..79752)
                     /locus_tag="L1V38_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1314654.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(79753..81576)
                     /gene="glpO"
                     /locus_tag="L1V38_000070"
     CDS             complement(79753..81576)
                     /gene="glpO"
                     /locus_tag="L1V38_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBN1314655.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(81590..83086)
                     /gene="glpK"
                     /locus_tag="L1V38_000071"
     CDS             complement(81590..83086)
                     /gene="glpK"
                     /locus_tag="L1V38_000071"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBN1314656.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(83222..84682)
                     /locus_tag="L1V38_000072"
     CDS             complement(83222..84682)
                     /locus_tag="L1V38_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1314657.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(84672..85967)
                     /locus_tag="L1V38_000073"
     CDS             complement(84672..85967)
                     /locus_tag="L1V38_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1314658.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(86299..86976)
                     /locus_tag="L1V38_000074"
     CDS             complement(86299..86976)
                     /locus_tag="L1V38_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBN1314659.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(87006..88097)
                     /locus_tag="L1V38_000075"
     CDS             complement(87006..88097)
                     /locus_tag="L1V38_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBN1314660.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(88198..88632)
                     /locus_tag="L1V38_000076"
     CDS             complement(88198..88632)
                     /locus_tag="L1V38_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1314661.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(89216..90673)
                     /gene="ascB"
                     /locus_tag="L1V38_000077"
     CDS             complement(89216..90673)
                     /gene="ascB"
                     /locus_tag="L1V38_000077"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1314662.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(90670..92565)
                     /locus_tag="L1V38_000078"
     CDS             complement(90670..92565)
                     /locus_tag="L1V38_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1314663.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(92623..94398)
                     /locus_tag="L1V38_000079"
     CDS             complement(92623..94398)
                     /locus_tag="L1V38_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1314664.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(94448..95944)
                     /locus_tag="L1V38_000080"
     CDS             complement(94448..95944)
                     /locus_tag="L1V38_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1314665.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(96138..97760)
                     /locus_tag="L1V38_000081"
     CDS             complement(96138..97760)
                     /locus_tag="L1V38_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1314666.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(98088..99401)
                     /locus_tag="L1V38_000082"
     CDS             complement(98088..99401)
                     /locus_tag="L1V38_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1314667.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(99646..99870)
                     /locus_tag="L1V38_000083"
     CDS             complement(99646..99870)
                     /locus_tag="L1V38_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314668.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(99890..100312)
                     /locus_tag="L1V38_000084"
     CDS             complement(99890..100312)
                     /locus_tag="L1V38_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBN1314669.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(100454..101164)
                     /locus_tag="L1V38_000085"
     CDS             complement(100454..101164)
                     /locus_tag="L1V38_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314670.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(101182..101679)
                     /locus_tag="L1V38_000086"
     CDS             complement(101182..101679)
                     /locus_tag="L1V38_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1314671.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(101716..102168)
                     /locus_tag="L1V38_000087"
     CDS             complement(101716..102168)
                     /locus_tag="L1V38_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1314672.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(102303..102908)
                     /locus_tag="L1V38_000088"
     CDS             complement(102303..102908)
                     /locus_tag="L1V38_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1314673.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(103358..103978)
                     /locus_tag="L1V38_000089"
     CDS             complement(103358..103978)
                     /locus_tag="L1V38_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1314674.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(103980..104849)
                     /locus_tag="L1V38_000090"
     CDS             complement(103980..104849)
                     /locus_tag="L1V38_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBN1314675.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(104872..105279)
                     /locus_tag="L1V38_000091"
     CDS             complement(104872..105279)
                     /locus_tag="L1V38_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1314676.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(105298..106587)
                     /locus_tag="L1V38_000092"
     CDS             complement(105298..106587)
                     /locus_tag="L1V38_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1314677.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        31216 a        22201 c        18726 g        34447 t
ORIGIN      
        1 tttcctgcat ataaatgaaa atgttcggag tcagccggtg caatcgtgtg atcactgaat
       61 tgaatatatc taaaagcgcc actttcctta tcttctgctt cgaatagata ccttacgcca
      121 cggtttcctg cctcgtaggt caagatttct ttccctacat aacgataatt tgaacgtttc
      181 gttgttccat tcttaaacgt aaatgccatc tctttctcac tgatcttgat tgaagcaata
      241 tctgtttgat agcccttcgt ataatattct ttatattctt gtgctgtctt atcctgattc
      301 aatttttctt tatattcaaa aacaggatca aaagtcccat cttctacata cgtatctact
      361 gtttgccaag ttcctgccca atctgaaaga gagcgatctt gtacatcctc gtcttcaaaa
      421 taaccgttgt agacgctctt ttcttttttg ggggtcaaag tatcttctag cgggttttct
      481 gtctctgtcg tttttttcaa cgcttcgagg tttgcttcca tgatagaaag atagttttct
      541 ccattttcta tttgttcatt cgtcaatcct tccaaaggat tcaatacttc taaagataca
      601 cctgcttcgt ttgctaacgt tctggcaata ctatctttgg cgttttcttc aaaataaata
      661 tagttgattc catgttcttt aacaaagtgt ttcagttcag caattctcgc cgcagacggt
      721 tcttcactag aagaaagacc agcaatcgat acttgattca atccatattc taacgctaga
      781 tagttgaatg cagcatgttg cgtgacaaaa gatctttgtt ttgcttgctt aaaggtttct
      841 tgataaagct gatggagtgc ttgaagtttc tcggtatagg ctgctgcatt ttttgtccat
      901 acttcctgtt tttctgggta agcttcaatc agctgatcac gtatgtttgc tacctgcttg
      961 attgctaaac ttggagctag ccatacatgt gggtctagct catgtgtatg gccttcttcc
     1021 ccgtgttcat ggtcatgatc atgtccttct tcacttcccg gaagtaaaag cataccttct
     1081 gtcgctttta tcgtatggac attgccttct tgtaatgttt tttggattgc ggggacccat
     1141 gtttccatgt tttcatcatt ataaacaaag atatctgtat cttggatctt tgccatgtct
     1201 ttagcagaag gttcataatc gtgggaatca gtccctgctg gaatcaataa ctctacttct
     1261 ccttcatccc cgacgattgc ttttgtaaaa tcatacatgg gataaaaggt cgtcatcacg
     1321 ctcaattttt ctttactgtc ctcggctttc ccacttgccc cgcaagcagt taacatacct
     1381 gctaaaacca gcatggccaa tatacctatc aatcgtttca tttatgacac tcctcttctc
     1441 atcttctttc atttgaatgt tccgattcgc ttttcgcaaa ccgtaatagt tacgttttag
     1501 caacaggatt taatttatca tatggttaaa agaactgtca agcgttttct tattttaatt
     1561 gatgagaaag tttatatgaa tgattgacga tatttttgca atcaacctct atcattttcc
     1621 ttttataccc gcttttgtct ataatgaagt tatagataaa ggaggaaaaa gagtgaaaaa
     1681 agaaacagat acaacgaatc gtttgatccg ctttttagga ggaaaaacct cttactatgt
     1741 tttaggaata gttatcttac ttgcgctgat catttatttt ttccatcaga tctcgtttat
     1801 attcaagcct gtcggaatca ttatcgctac tatcttgccc ccattattgt ttgcactgat
     1861 cttgtattat cttttggaac cagtcatcaa acgtttgagc aagcaccttt cgaggaactt
     1921 gtcagtcatt atcgtttatg tgattatttt atttttattg gggcttggaa gcatatggct
     1981 tattcctttt cttgaagaac aggcaaagac attgatcagt agtttgccag atttgtttca
     2041 agattttcaa gagagtctcc gacaattttt ggagaaaaca ccttttgccg attcatttaa
     2101 tcaatttttc gcttctattg acgacgtgac gtctgatata gctggattta ttggaaatta
     2161 ttgggaaagt ggcgcacaac ggatcagcaa cattttttca actgttacag ctatttttat
     2221 tactttattt actggtccaa ttgtcgcttt tttccttttg agagatcctc aaaaatttta
     2281 tcagtcagtt ttagcgattg tcccaccagc atttcgtaca gattttaaaa atttgacaaa
     2341 gattgctaat caacaattgg gttcatttct aaaggggcaa atcattgctt catttatcct
     2401 tggagcagtc tactgggttt gtttcttact gatcggatta gaatttgcta gtgttttagc
     2461 tatttctgct gggttgttat gtatcattcc atatattggg ccgtttatcg ccttctttcc
     2521 aggtttgatc attgcattcc aagactctac ttttatggct gtcaaatttg tcattgtctg
     2581 gtttgccgta caacttctcc acggtgactt ggtgattcct cgagtaatgg gtgatcgttt
     2641 acagatccat ccgattacga tcttaatcgt tttacttgtc atgggtgatc taatgggaat
     2701 tgtgggcgtt atttttggta ttcctatcta tacgttagtc aaattactcg ttacttttat
     2761 tttccgtaaa ttcaaacaac gctacaataa attttatggc gataaaggag agtatgaaaa
     2821 ctcttcattt tctgaagaag attattttaa ataaaacaca aaacgtcgat cttacgagaa
     2881 tagctcgtag gaacgacgtt ttgtgttttt gttttaattt ttcagcaaag caattgcctg
     2941 gtatggtttt agctccagac tttgatgaag aacagtatcg gaataattat cgataagaat
     3001 attggcttct gtgaatcctt ctgggatggc gatccttgta tctttatcat agaaatttgt
     3061 taatacaagc agctgctgtc cttcaaattg gcgaagaaag ccataaactt ccggatgatt
     3121 tgcttcataa gcatgataat ctccttgtgc aacgattgga tatgtttttc tcagccgaat
     3181 caatttcttg taataggaca aaatagaatc ttcagaagat agttcttttt ctacattaat
     3241 ctcttctagc ttgcctccaa cttttaacca aggtttccct gtagtaaatc ctgcttgttc
     3301 tgtgtctgac cattgcatgg gtgttcgaga gttatcgcga gattttgctt tgatccgacg
     3361 aaacgcttct ttttctgtga atccttgttc aaggagtaac ttataagcat tcaaactttc
     3421 tacgtcaata tagtcggaaa tcgatgaata gtctgggtcg atcatgccga tttcttctcc
     3481 catataaata tagggcgtcc cacggttcaa atggatcatg gttgctagca tctctgctcc
     3541 ttgttttcga tactgatcga tagctacaaa tcgattgagc gcacgtggct gatcatgatt
     3601 attaaaaaat agagcattcc agccgttacc ctcactcatc ttttctcccc atgtatgaaa
     3661 tagtcgcttt aattctgcaa aatcaaatgg aggagtagac catttattcc cattttcata
     3721 atcgactttc aaatgatgga aattaaagac cattgataat tcttctctac taggttctgt
     3781 atacaagata caattttcga tcgtcgtaga gctcatttca ccgactgtga tgatagtgga
     3841 atccgtccca aacgttgctt ggttcaattc ttttagatac gtatgggtga ttggtttgtc
     3901 cgtatattca ggtttgccat cattttcttt attatttttc aattgttcgt ctttaccgat
     3961 aacattgata acatcgaaac ggaatccttt tacccctttt tccatccaaa aacgaacaac
     4021 tttgaatagt tcctctctta ctgcttggtt ccgccagttc aagtcagctt gtgtccgatc
     4081 atataagtgc aaataatatt tccccgtatc tccaaatggc gaccaagcac ttccaccaaa
     4141 ttttgatacc caatccgttg gctcttctct taaaatgaag aagtcctgat aatgctggtc
     4201 ccctgctagt gcttttttga accattcatg ttctgtcgaa acgtgattca gcaccatatc
     4261 gagcatgatt tctatccggt atttctttgc ttcggctatt agctgttcga attcctccat
     4321 cgtaccaaag ataggatcga tggctgtgta atcagagata tcataaccgt tgtctttttg
     4381 agggcttgga taaatagggt ttagccaaat catgtcgatg cctagatcat tcagatacgg
     4441 gagtttttct ttgattcctt ttaaatctcc aattccatca ccattactgt ctttgtaaga
     4501 tttgggatag atttggtaaa tgactttgtc tttaaatgtc atggatattt acctccattc
     4561 aactgattta ttacctacca caacttatat atacaagtta tcatttatta ttataactga
     4621 accgaaagcg tttgtaaaat ttatctttat acattctaag aggtctgttg cccaataaaa
     4681 aacaagagat cagacatgta tttgtctatc ctcttgttta aaatagcaaa atattcttgt
     4741 ttcttctata aatggtgttc aaaagctttt atctacggca atcagtcttc tcaaatgtaa
     4801 aacatgagga gctaatttta tttgagtatt ctttttgctc gatgcaggac ggctttttta
     4861 caacctctga ttcatggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
     4921 aatatgaaaa actattttgc cgtttgtttc tctaatactc aggtcaaacc gctgatttca
     4981 caacctctgt ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt
     5041 gaaatgggta acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac
     5101 ataagcccac catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa
     5161 gatgaagtca gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa
     5221 gatgatattt tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt
     5281 tattgtagat aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac
     5341 gataaaagcc agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc
     5401 cattgattct tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc
     5461 tgtggcaagc agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg
     5521 cagcaaaaat gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga
     5581 catataaata aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc
     5641 tttttgatct tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc
     5701 tactttttgc gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc
     5761 agttaaatgg ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact
     5821 ttgcgaagca tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc
     5881 atttactttt tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga
     5941 tgaatccaat gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac
     6001 agaacttaga gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat
     6061 tccgataatc gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt
     6121 ttgattaaag ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc
     6181 tggcttcggt gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa
     6241 aacgatcatt gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg
     6301 cggccagtca taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa
     6361 aatgatcctt ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga
     6421 ggctagactt gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc
     6481 ctttaatgtc ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt
     6541 gatcaatgcg gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg
     6601 atcagacaga tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta
     6661 tgatggttta gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga
     6721 ggccagttca cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg
     6781 ttgagataat gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc
     6841 tgactgttgc gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg
     6901 tgctttgcca tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt
     6961 cagctcttct aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt
     7021 ttgctccatt ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa
     7081 atcaagatat aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa
     7141 ataatcgacg ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa
     7201 tggagaacgg acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat
     7261 ctgataaata tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg
     7321 gtttggtttt tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt
     7381 gttataagaa aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt
     7441 tcctgtttct acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa
     7501 gccaccagta gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat
     7561 cgttttttgc atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat
     7621 gacaataagg atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc
     7681 tttaagatat gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga
     7741 aggatgatca tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc
     7801 agcgatgggc gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct
     7861 gctagcgttt tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt
     7921 cggttcatca cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct
     7981 ctgctgttcg cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac
     8041 ttgcctcaat acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac
     8101 attttctttt gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc
     8161 tgttcgtcgg taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat
     8221 aatgatctga ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt
     8281 tcctgctcca cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat
     8341 atcgtcattt gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac
     8401 ttcgacatac ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat
     8461 cgaatgcgtt ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg
     8521 aatcctttaa tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt
     8581 tatttgaaag aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa
     8641 aaactgcttt tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc
     8701 cacacactgc agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta
     8761 ccgctgcctt gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac
     8821 aaactgatat gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga
     8881 aggattcttt gaaagataca gataatatgt tgactatcac aaaatacaat ccaagtgctt
     8941 tttttggtac ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa
     9001 gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt
     9061 accatatcgt gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt
     9121 tcataaaaaa gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag
     9181 ctatccaaca aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt
     9241 catgggaaaa taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac
     9301 aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa
     9361 tggaaatacg gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga
     9421 attaggctat cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat
     9481 tggtgtactc gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga
     9541 ggatatcttg tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca
     9601 aaaagaaatc gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc
     9661 gacttctgct gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt
     9721 cattgttttg gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt
     9781 tcgcggtggt tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct
     9841 tgtctatcct gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc
     9901 tcttgatgtt taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa
     9961 acaaggtggc taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc
    10021 tttaaatgat gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat
    10081 ccctgaagac tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc
    10141 gaaactgaca acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt
    10201 gttagatcgg atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt
    10261 agaaaaaaga ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc
    10321 gaactattaa aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg
    10381 agatagttgg aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac
    10441 actacccttc gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt
    10501 tttcacgctg gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca
    10561 cggacatctt ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta
    10621 ctgacaaaag aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga
    10681 caagcaatga ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca
    10741 aataatgctt tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac
    10801 tttattattg ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca
    10861 aaagacgcag gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact
    10921 gaactacttg aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca
    10981 ggaatcagag tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta
    11041 ggtattggaa cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa
    11101 gaacacggta tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat
    11161 acatttattg gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg
    11221 atcctttatg gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct
    11281 atcccttacc gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa
    11341 acaaacatga aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg
    11401 gggcactttg ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa
    11461 aaaatagatt tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt
    11521 ttagaagaac ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg
    11581 gaaatattgg aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat
    11641 gaagaaatga aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca
    11701 ccttacgcca atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc
    11761 ctgaacagat ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag
    11821 acaatattga ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc
    11881 cagtagccaa tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac
    11941 tcgatagata tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga
    12001 cgcgtcaaat cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg
    12061 gtttgatatc ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa
    12121 aaggtctggt tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc
    12181 atattttgtc tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt
    12241 ctgctgccaa aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga
    12301 ttgaaccgaa tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg
    12361 ggattcctgt agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt
    12421 tcttttattc ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag
    12481 tatttgtacc tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc
    12541 ctgcgggtgt ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta
    12601 acggaccgat cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta
    12661 tccaatgggc tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa
    12721 tcgttccgtt gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc
    12781 tgcgaagtaa acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac
    12841 ttgcgggagt gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg
    12901 ttgctgcttg cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag
    12961 cgatcgcttt tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt
    13021 tctggtactt agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta
    13081 gcgggtttga tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag
    13141 atgtttatca catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt
    13201 gatactttcc aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt
    13261 tatccccaaa caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg
    13321 ctcgttgctt atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa
    13381 aagcttttcg acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga
    13441 aaatcaatga aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct
    13501 agctgctact tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga
    13561 taatcaaata gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag
    13621 tgaaacaacg gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc
    13681 gaccgagcca actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac
    13741 atattccctt acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc
    13801 ggattcccct gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt
    13861 agcggaaacg aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt
    13921 cgctgttaat ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa
    13981 caatttatct attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac
    14041 tgatcctagt gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt
    14101 gggtaataac aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa
    14161 cagcgggaat tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca
    14221 gagagaacca aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc
    14281 tcgtccaaat acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt
    14341 tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc
    14401 aatcgttcga gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc
    14461 aaatactttt gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta
    14521 tatcggtggc tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc
    14581 ccaacctggc gacctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat
    14641 ctatattggg aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac
    14701 ttctatttca gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc
    14761 tgcttcaggt tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca
    14821 tttcagtcaa aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga
    14881 aatcgggcaa aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag
    14941 tggatctgga aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg
    15001 atcatataaa ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag
    15061 ctaccaaatc cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta
    15121 tgccgacttg atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa
    15181 gtcggaaaca aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga
    15241 tcgccaatat tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga
    15301 tgaaccgaaa aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc
    15361 taagcgattc gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga
    15421 attttcaacg ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg
    15481 ggatttgtgg aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa
    15541 agctgcaact gttcctgtac taaccttgtt aaggttagac aaatcattct ggcttgatct
    15601 gcctttaaag aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta
    15661 atttattcta tttctttata tttattttgt attccgttac aaactcgcgt acttggttag
    15721 gttccagagt gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct
    15781 caaatgtgat accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc
    15841 caaaatttgc tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt
    15901 tttcatctgg gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa
    15961 atggatgatc gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac
    16021 ctaatttttt aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg
    16081 taggcgttgt atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt
    16141 cgtcgattga ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga
    16201 atactgtttt gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca
    16261 gcgtataccg tacttctaca tctaaagttc caggaaatcc gttttccata tctgggctag
    16321 tctgatagaa aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct
    16381 tggcttcaaa gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta
    16441 cttcgaacgt ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc
    16501 cgattgaagc accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta
    16561 agatcaactc tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa
    16621 gatcactgac agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt
    16681 cgccaaaatt ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac
    16741 tgattccagt atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa
    16801 aatttactat attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca
    16861 acctcttttt ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    16921 aacgaaaaat atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc
    16981 tttttcacaa tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt
    17041 agatgaaata caatacgaag aatatcgtaa acggaaccca aatatctttg tatggatttt
    17101 gcatgaatag accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg
    17161 gtgctaagaa taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg
    17221 ttcctatctt ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct
    17281 tgaacatcaa acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa
    17341 attcaaaacc agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt
    17401 actctacttt ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg
    17461 gtttcaggtt tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt
    17521 tcagttgatc aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca
    17581 attcatagct tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt
    17641 tttctttcgt gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag
    17701 ccgcaaattc acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag
    17761 cagaaagtgt tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca
    17821 tcactagatc atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta
    17881 atcctaccgt caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt
    17941 gtgtatattc acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca
    18001 atgaaatctg ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa
    18061 tgaaataagt tcctaatacg atcgtaacta aggctacccc tataccaaag acttgatagg
    18121 tccccacgtg tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt
    18181 caaggaaaaa caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca
    18241 atgctaaaat cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca
    18301 aaacagcaaa aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg
    18361 aaatattgag atctaactga tccactaata atcggtggac gatacttgtc aatcctacac
    18421 cgacagctga acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca
    18481 tctgtgcgat ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc
    18541 gcatcgtcat caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta
    18601 aaacagaacc gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa
    18661 aagcttcgtt gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc
    18721 ctgagaataa caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc
    18781 aaagcatagt caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga
    18841 tagaaggaat cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg
    18901 atgaataaaa tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc
    18961 gatacatgat cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg
    19021 gaatccagcg cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca
    19081 cgtgcggcgg cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa
    19141 atatgagaga tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt
    19201 ctgacgcctt gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat
    19261 aaattgaaat cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt
    19321 ccttttaatg tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct
    19381 aatgtggata aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca
    19441 ataaattcgc ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca
    19501 ttgttttttc cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc
    19561 cctacccttt aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt
    19621 catacgaagt gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa
    19681 gcggtcgagt caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc
    19741 caggcaggat atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt
    19801 ttgtaccatc tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg
    19861 cgattttcac ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt
    19921 tcactttttc cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct
    19981 gccttcgaat caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa
    20041 aaagagttca agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt
    20101 cacttacggt ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg
    20161 attgagacaa gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct
    20221 tgtccatctt cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg
    20281 gtttgtcgag cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt
    20341 tctgttgcat aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct
    20401 aaacgctctt gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc
    20461 gtcaaatcat tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct
    20521 gtctcacttt ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct
    20581 gtatcaacga ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca
    20641 ttgactttta aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt
    20701 gccaaaggta tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa
    20761 aacaaaatta cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac
    20821 gtgatcaacc aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct
    20881 aaatagaaga aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa
    20941 ccattgatat aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca
    21001 ataaatatct aatgttactt ttttaatttt tttttcgaat acgcgccatt acaccttcta
    21061 gttctaactc tttgtcttca gtgatgtacc aaccgcttgc ctgtgtccct ccggctgcct
    21121 gcggtaaata atccaatttt gttcgaaccc agtgcttttc ttctgtaaaa tagtcttcta
    21181 ccaagacctc tagatccatc cctgctgaaa gaggcaaatc ttcccgaaca gatttaaaga
    21241 taaatcgttc cttcttccca tcatacttca atattcctgt atcgataatc ggtaaagaat
    21301 aataatccag ctctttcttc accgtcaata aatgtttgaa aacttcatgg tacacttgct
    21361 ctaattggcg accttctgaa ttgttcgggt aattaaccat cactttttct ttgtctggat
    21421 catagaaggt ttggcttagt tgagtgatat aagtatgtaa tctttccatt tctgttttta
    21481 acttttctct ttgaccttct tctaccttca tatactcttt caccctgttt tctttttaga
    21541 tattttcttt cttattttac tatagttatg tgcgttaagc gatgaaaaac agcaaagatt
    21601 ggaaggatct ttgctgtttt ttcttaaaat atccagttga gtacaggatc aatctgtttc
    21661 attgtcctct tgatccgtcg taatattgat cgatgtgtct ttagcagtga tctttagctt
    21721 tttctgtcct tgttctaaca aagtatttgt tattggctgg tagtcttttt caatataaga
    21781 ttcaccagac gtttggatag tatagccact gttttccatc tcatgcaaag ataaattgcc
    21841 accgtttagg atgacttttc cttctttgct gatcaaactg tcttctagat ggaagttgct
    21901 gttttcacct gtgacgatca agttatccac attggcctca tctaatcgaa gtgagcctaa
    21961 ttcatctttc gcagttattg ttcctcctgt aaattcattg aacgataccc agccatcatg
    22021 tgtcttagta ttcacttttt tgattgatac ttcgttgata tcaattgcac tattattccc
    22081 ttcgattgtc aattcagata attcatgatc tgcagggaca acaatagtga tttgtgcact
    22141 tgtgtcttct aaactaatga ttgcacctgt tgattttttg actgcattca cagtcaacac
    22201 gccatttttc tcctttattt ctggcttttc tgtcttatca taagtcgttt ttatctcaaa
    22261 atccaatccg cgtatgaccg aaactgtttg attttctgca tggatgacga ttttgtttgc
    22321 atccttgatt ttttttgtct cagtaaccat atcgatcaac cgaggaccat tatcccaagt
    22381 cagactcttt tgagcgccta atgtataagt tgcacctgct aggaggccac cagtaagcat
    22441 cagaccaata ccggtaatca aaaaatgttt caatctcaat ttatgtgtcc tccttcaaac
    22501 gcccgctgaa tgcagatctc tttttgtaat aaaacgtcgt cccatccatt taacaaagtt
    22561 catcatgaca taaaaaagcc cttttgttcc tttcagcaac agtggcgaaa taaatactgc
    22621 gcttcctgtg gcgaacagac cgacaccgat aaagaataat ccactcagaa tcgattgtcc
    22681 aaacacactg attcctgaga tgatcatgaa taggccaaca cctaagatac tgatacataa
    22741 aacatagata ctaaaaatga gcgctagtaa agcaaccaat agtcccccaa taaccaatat
    22801 aaaccccagt gctagtggaa tgaggacagg agaagcaaat aaaccgataa tgattaacca
    22861 aatcaggcga atttgtcttt ttggattttt cactaactcg ttttctgctt gttcttcttc
    22921 tgaaaagtaa ctgattttta attttaaggc aaactgcttt ggtgtaccat attcatcaat
    22981 gatctgatct aatgtttttc cagaatctaa aaaatattcc tcataatact ggatcaaatc
    23041 aaaacgatcg tcttcaggaa tttcttgaag atgatccaca acttcattca aatattcatt
    23101 catttgtgct ctcctccaat aaccggtcta aagaatctcg aaaaacaatc cattcatcaa
    23161 taatttcttc taaatgacga cttcccattg gtgtcaacga gtaatatcga cggtttctgc
    23221 cttcaaaagg ttcatcatag gtctcaagat atccttcttt tttcaatctt ctcaaaaccg
    23281 gatatagtgt agattcactg acagagagac tttcttgtac gatttttgtt aaggcatacc
    23341 catacatatc ttccttgctt aatgctgcta gcacagtacc atcaagaaga acagttggaa
    23401 tctggatgtg cattacgtca ccttctattc tcaagtgtaa tattttattt caatctatat
    23461 tatacaacat ataatatagt ttcaaaatca gtttgtcaaa tacaaaaaaa ctgactaaaa
    23521 gatttgatcc tttttagtca gcaaaaaatg gcttctcttt gatttttatt ataacagtgg
    23581 cataatccaa tttgtccaca tccagctcag tggcatgata acgatcattg caggtatcat
    23641 gtcagctact gggaacattt tcacgttgat cattctaaaa ccggtagcga ccatcaagaa
    23701 tccgccgcaa gctttaaaat ctaagatcat gtctggtgta gtcaatggat aaataaattt
    23761 tgccaataag aacaaaatat aaaaaataat gaattgggga attgctatca cagaaacgac
    23821 ataccctaaa ttacacgcaa aaatagctgc tgtgaaaaaa tcaaggacag atttagaaat
    23881 caaaatcgta ctgtctcctg tcatcccaga atctaaactt ccatagatcc ccgtaccact
    23941 tgcacaaaat agaacaatga ccgtcactaa tgtgctgata aattcatcgt gggtcatacc
    24001 aagcttttca ctagggaaga ttttagaaat aggtacttgc atcagcgcag cccccttatt
    24061 tatcccatta cctaaatgaa caatcaaacc aatcgctgtt cctatcacta aagcaaaaat
    24121 aacagccggc atatttttca tcggcgcaat ggaatagatt cccatcccca tcgaacacac
    24181 accaaaaacc atcgtcagct gtgctttaaa atgttcactt aatttatttc ctactaatcc
    24241 gccaattagt ccgccaaaca aaacggaacc tacattgatc aaaactccag ttggcatcaa
    24301 aaaactcctc tctttttcta cgaagcgaaa aaaatcagaa aaatttctgt aattattgct
    24361 ttcgctgcaa gaaagattgt aacagacaga gaagattaca ccaattcatt ttttgtgtta
    24421 aagtattctt tattggaata agtaggagga atatgatgga tatccataaa ttcgaagttt
    24481 ttcttgattt agccgaaaca atgaatttca ccaaaactgc tgatcgacaa ttcaccaccc
    24541 aaggaaatat ttctaaacag attctttcgt tagaaacaga attagacgtc aaattattcg
    24601 aacgcgccca tagaaaaatc gaattgaccg aagctggaag cttattgctc ccatatgtaa
    24661 aaaatgtcgt agaacaatac catgctatgc aagaagtgct tgaaacctat acgaaagaca
    24721 acaatctttc attaaatatc ttaacgatac cgacaatgat caattataaa ggtttttcca
    24781 aaatcaccga gtttttgaaa cgccatcctg aatttacagt ccagttgaaa gaagtggaaa
    24841 gtgtcgaatt aacttacaat gacgccaatg aacatagtga cacgatccac tttgctagaa
    24901 gtttccaggc cccaccaagt tcgattgagt ggttgcctac tgaaacagac gattttgtag
    24961 cagttctacc taaaaatcat cctttagcta gtaaaaagaa attggatcta agcgaactga
    25021 aaaaggagaa ctttttgctc cttggcccca ctacgaactt gtatcaacct gtactagatc
    25081 tgtgtcgcga agctggattt gaaccaaaaa tctcttataa aggagcaaga atcgacttga
    25141 tcatcaatat gattgcaaat gacatgggga ttgctattgt tatggaaaaa acagtcaaga
    25201 atctattaaa agaaaatact gtgattctcc ctatttctcc aacaacagag agttatcttg
    25261 catttactcg taaagtcggt gagcattctt tggcttcaga tacattttgg gagtatttaa
    25321 atcaagaaga aaactaagcc ctacattttc tgtccatcta tccacccaaa aaaagagagc
    25381 gacgcatgac tttcgctctc tttcttgcat catgtccttg tttcaatgac acctctaaca
    25441 tttctcgtag ttcaataaga aagcagcgat ttttatgcca aaagaaccgt aagaacattt
    25501 ccctaatcac aaaaaaacga ctaaaaaccc ctaaaaacct tcaatagaat ttttaggggt
    25561 tttattcttt ttcctattgt ttacttaacc gtatcattgc tgtcgttcct actccttcga
    25621 tactgctata atcaatacgt ccatcatgca gttctagaat ttttttaacc agtgaaagtc
    25681 ctagcccatt cccagaaatt tgacgacttg tatctccttg ataaaatttt tcaaacattc
    25741 gatctctggt ctcttcattc attcctacac ctgaatcggt cacttccagt acaatctctg
    25801 tggctgtctc aaatagtttg atatgaatct gtccattgat ttgattgtac tttatggcgt
    25861 tatccatgat attcagccac acttggtaca aaaactcttc attgcctgtg taatttactg
    25921 cagcaagttc gatatccaat tctagctgtt ctttctccca tttaggctga aaaaaaacga
    25981 ttacttctct gatttgttca tctaatcgat actctttctt ttccagttgg atacgctggt
    26041 tttccagttt gttcaatttt aagatgttct ctgttaattg tgaaagctgc gtgatacttt
    26101 cgataatccg atataaaaat atttggcgtt cttcgtcaga gagatttggg gcttgtaaca
    26161 attgaacata tccttggatt gttgctagtg gtgttttgaa ttcatgggat acactggaca
    26221 caaagtcatt cctcagtgtc tcgatactat tgagttcttg gaccataacg ttgaaatctt
    26281 tatacagttg ctgtacttct gctactttct gctgttcatc cattcgaatc gaaaaatctc
    26341 ccgttgctac cagactcata tttgtcccta gcgcactgat tggatgcagg atacgccgcc
    26401 caacaaaaat cgatattcct gtacccacga ccatactgaa ccccgcaaag acgaataacg
    26461 ggtataacgt tggttttcca gccgattcag caggcgagat agaatgtcga gacaataaga
    26521 aaataaaacc gagaaaacac agcagtgtca ctaagatcga aatgaagaca atactagcaa
    26581 aatagatcca taattgtgaa aatagctttt ttttcatctt taaataaccg ccttatagcc
    26641 tagtccccgt actgtgatga tttgaaaatc ttccgtcttt tcaaaacggg tccttaaacg
    26701 tttgatatgt acatcgatcg ttcgttcttc tgtattcgta tctaatcccc aaatatcatc
    26761 catcaactgt tggcgagtga agatcttgtt gggataagac agtaatttat acagaagcag
    26821 aaattctttt tgaggcagaa tcaacgaatg ctgatcttgt aacactgtat aagcatctag
    26881 ctctaatttt gtttgtccga ttatcaagct actgctgtaa ttgatctttg aacgtcgaag
    26941 caatgcttcc acacgtagga tcatctcatt gacatcgatg ggttttgtca tataatcatc
    27001 tgctcctaat ttgaacccgc gtttcttatc ctcaaaatcg gcctttgccg taatcattag
    27061 aacaggtgtg tcaaatctgg tgctacgtaa tgagtctagc aagtcatagc catccatttt
    27121 cggcatcatg atatctgtaa tgattaattc tatacgtgtc gcttctagtt ttttcagcgc
    27181 atcctctcca ttcaatgcgg tgatgactga aaagcccgct cgttccaaca cagaacggta
    27241 aagcaactgt aattgcggat catcttctac tactaaaata cgattcattg atctccctct
    27301 gttttttgaa aaatttctag attttttctt gtagttcatc ttcagttaac atttatttcg
    27361 tatactacga tcattgttct gatatactta ttagtatacc gaatatttca atacgggaga
    27421 agggtgatta tgcttcaatt aaaagatata aaaaaatatt ataaagtcgg cgaaaccacc
    27481 accaaagcat tggatggtgt gtctgtcgct ttcagacaaa aagaattcgt agcgatttta
    27541 ggtcctagtg gttctggtaa aacgactatg ctgaatgtga ttggtggact agataattat
    27601 gattccggtg atatggtaat caacggaaag tctactaaag actttaagga cagtgactgg
    27661 gatgcctacc gaaacaactc tatcggtttc atttttcaaa gttacaactt gattggtcat
    27721 ctaggcatta ttgaaaacgt tgaacttggg atgacattaa gtggtgtttc taaagacgaa
    27781 aaacgaaaac gggcagaaga tgcattgcac cgagtcggct tgacaaatca tatgcataaa
    27841 aagccaaatc agttatctgg tggacaaatg cagcgagtgg ccatcgctcg agcactagcc
    27901 aatgacccag atatcctttt gtgcgatgaa ccaaccggag cgttagatac agaaacaagt
    27961 atccagatca tggaattgat ccaagagtta tcgaaagaaa aattagtgat catggtcaca
    28021 cataatcctg aactggccca tcaatacgca gatcgaatca ttgaattttc tgatggtaag
    28081 atcttaacag attcccatcc tcacatcgaa cgaccaaaag atgatcaatt taacttacgc
    28141 agaacaaaga tgagtttttg gacagcgtta aagctttcct tcaacaatat ccgaacaaaa
    28201 aaaggacgta ctttcttgac ctcctttgct tccagtattg ggatcatcgg aatcgcgatc
    28261 gttctgtccc tttcttctgg attccaaaaa caaatcgata acacgcaagc tgaaacgatg
    28321 gcgaaatttc cgattactat ttctaaggta acgactaacc agactcgtga cgatgccgga
    28381 ttgggtgcaa gcaaagcgga ttatccagac agcaaaacga ttactgcaaa agtcagcgaa
    28441 gaagataaag cacagcacac gaataagatt gatcaaacat acgtcgatta cgtaacagac
    28501 atcgatccta acttaagtaa taatatcgga tttacccgta ctacaggaat caatctttta
    28561 cgtgatgtaa atggcaaagt acagcctgtc agcttctcga atcaaaatcc tgatacggaa
    28621 tctctttctt tatctagtac gatgtcagca atgacaggtg tgggagtgtc aagtttccct
    28681 acacagcttg acactagcaa agaaaacttt ttaaaagaca attattcttt acttgccgga
    28741 agttatccag cctcagcaac agatgtcgtg ctgatcgtag acggcaataa taatactaat
    28801 atcaacgcat tgaagaatct tggatttgat gtgaaagaag acgaaaaact tgattttgat
    28861 gatatcgttg gtacaacatt caaattagta aacaacaata cttactatac aaaacttcca
    28921 actgggaatt ttatccctaa tacagattat gatgcgatgt atcagaatgc ttctgatgaa
    28981 ttgaagatct cggggatcct acgcgtgaaa tcttcttcta caatgaatct cttatctcca
    29041 ggaatcgctt atagcgatca attaacgact caaatcgtca acgaaaacaa agaatcagaa
    29101 atcgtcaaag ctcaaagaga cagtggtgta aatgtcttaa ctactgaaaa agttgacgaa
    29161 aatgccaaac aaacattgct tagttattta ggtggagaca gcttgccttc aagtatcatg
    29221 atttatccga acaattttga agacaaagaa aagatcttgg attatctaga tgattacaat
    29281 aaaggcaaat cagatgaaga taaaatcatt tatactgatt tagctggaac gatgactgaa
    29341 ctgactggcg gattgatgga tgctatcact tatgtcctta ttgcttttgc agggatctct
    29401 ttagtaacaa gtatgatcat gatcagtatc attacttata catctgtgat tgaacggaca
    29461 aaagaaatcg gtgtactaaa agctttaggt gcacgtaaaa aagacatcac tcgcgtattt
    29521 gacgcagaaa cgtgtatttt aggtatttct tctgggatat taggtgtgtt tattgcatgg
    29581 ctagctacgt tccctatcaa tagcatctta tacaacatga cggatctaaa aaatgttgct
    29641 caactaaatc ctgtccatgc gattattcta gtgatcgtct ctactatatt gacgatgctt
    29701 ggcggtcatc ttcctgcacg aatggcagcg aaaaaagacg ccgctatcgc tttgcgtgca
    29761 gaataaggtt gtgacaacca catttagatt tgagtcataa gagcgctgaa atagtagaaa
    29821 acagcaagaa acgaggaagt aatatgttcc ttgtttcgcg ctgttttttt taattatttt
    29881 ttataattct ggtatacttt tctttccttt gtaccacaac tcttctggcg tatacctgtc
    29941 ttttccattt atgaatactg ttccatctgc ttcaatcgtt acttcagtcc caatccacat
    30001 attacgagaa agtgcgagaa gattttttct ttttcctctt cctttttttc caaattgcaa
    30061 ggcatcggtt atctcttctg tccaatgaga tttcacgtat tttacttctc cgttttcaaa
    30121 tgtaactttc aaaatattcg ctatattttc cacttttact gctttaggaa atgactcctc
    30181 catttttttc actttccttc ctccaacact aagtatgcgc tttcttttag tgataagtat
    30241 atcatagttt attctattat caaaaaaacg catccattcc attgtagaat actttaccga
    30301 acaagttgaa ttgttttcct ctttttcacc ttttactata gataggtaaa gacaactaag
    30361 gaggaatctc tcatgacaga tcaaccgtat gatttaagaa aagtcatcga agaactaaaa
    30421 acacttccag gtcaatatca cgaaacagat attgaaatcg atcctgaagc agaattatct
    30481 ggtgtttacc gttatatcgg tgctggcggt acagtaaaac gtccgactca agaaggacca
    30541 gctatgactt tcaacaatat caaaggtttc cccggcacac gtgtgaacat cggaacaatg
    30601 gctagtcgta aacgtgtagg tgaaattttg caccatgatt atcgaacact tggtcgtttc
    30661 ttgaaagacg ctgtagaaaa tccaatcaaa cctgtgaaag tagacaaagc agacgctcca
    30721 gcacaagaag tcgttcatct agctaccgat gcagacttcg atattcgcaa cattttgcct
    30781 gcacctacaa atactcctga agatgctggt ccatacatca caatgggtgt agtcttagga
    30841 tcagatccag aaaaaacaat gagcgatgta acgatccatc gtatggttct agaagataaa
    30901 gatacgatcg gtatgtacat catgcctggc ggacgccaca ttggtcactt ccaaaaacaa
    30961 ttcgaagcct tgaataaacc aatgcctatc actatcaata ttggtttaga tccagcaatt
    31021 gccattggca cgactttcga accacctacc actccacttg gctacaatga actatggtgt
    31081 gcaggagctt tgcgtaacga acctattcaa atcgttgatg gtatagcagt cgatgaagtg
    31141 ggtattgctc gtgctgaatt catcattgaa gcagaaatca tgccaaatga aacaatgcaa
    31201 gaagatatca acacgaactc aggaaaagca atgccagaat ttcctggcta tactggggat
    31261 gctaatccag ctgtacaagt agtgaaagtc aaagcagtta ctcaccgaaa agacaatcca
    31321 atcatgcaaa caacgattgg tcccagtgaa gaacacgtat ctatggccgg tattcctaca
    31381 gaagcaagta ttcttgcctt ggtcgataaa gctattccag gaaaagtagt aaatgtctac
    31441 aatcctcctg caggtggtgg taaattgatg accatcatgc aaatccgtaa agaaaacgaa
    31501 gcggatgaag gtattcagcg tcaagcagct attcttgctt tatcagcctt caaagaattg
    31561 aagacagtca ttttagtcga tgaagatgtt gatattttcg acatgaacga tgtagtttgg
    31621 actttcaaca ctcgtttcca aggagataaa gatatcatcg tgatcccagg aatgaggaac
    31681 catccattgg acccatcaga attaccagaa tataatcctg gctctattcg tttccgtggg
    31741 ataagtgcaa aaactatctt tgacggtaca gttcctttcg atatgaaaga acattttgta
    31801 cgtgcaaaat tccaagaagt agaagattgg gaaaaatatt tgaaataatg aatgatctgc
    31861 aactgttttg acatcataaa aaggagtgcg gaaaatggaa caattggcac aacggaagaa
    31921 aaaaatcgtg attggtgtaa gtggcgcttc aggcaccatt tatgccatca acctagtgaa
    31981 gaaactaaaa gaatatccga tgatagaaac acacggaatc atcagtccat gggcaaaaca
    32041 gaacttaaag ctggaatccg acttatcact aactgaattc gaaagcctgt ttgattacca
    32101 ttattcaaac aaagatttag gtgctgctgt cgccagcgga tcatttttga ccgatggaat
    32161 gatcatcgta ccggcaagta tgaaaacagt cgcaggtatc tctgttggtt taggcgacaa
    32221 cctgattgca cgtgctgctg atgtaacaat gaaggagcaa cgaaagttag tcattgttcc
    32281 tcgtgaaacg ccattaaatg ccattcactt ggaaaacttg actaaattag cacgactagg
    32341 tgtgcaaatc ataccaccaa ttcctgcttt ttataatcag cctcaaacga tccaagatct
    32401 tgttaatcac catacaatga aacttttgga tcaatttgaa attgtaaatg agcattcaaa
    32461 acgttggcag ggtgattaat atggaaaaag aaacgatagt tgaagtaacc aaactaggtt
    32521 tcacgatcca agctgctgtt aaagtaatcg gtaaagactt attgatcact ttaacaggcg
    32581 gagatacacc acatatcgga acagtcacta cattttctcg tgatacagag atgcaaactg
    32641 tacgtttccc tagccacgat ggtcggttcc ataaagacga tgtcttagcc gaaaaaatag
    32701 ctgtgatcat caaaactgcc gttccgggaa gttgtacgat cacttccggt atccatgttg
    32761 accatatctc caatgcacaa atcaacgcct cttttccgat gtcagaagag ttaggttaca
    32821 agattttaga ttggttggaa aaaatagatt tccatatcaa ataaccagtt tattataaag
    32881 atggtgaaaa accattatga aagaagaggt tgtgaaatca gcgttatgac ctgagtatga
    32941 gagaaaaaaa tggaaaaata gcttctcata ttttgccgtt tttgagctaa taccgaggga
    33001 cagctgattg aacgccgttt atcaagaggt tgtgataaag ccgcttcgtt tcgagtagta
    33061 agaaaaattt tgtaaacatg ggtttccaca tttttgcata aatttgactt actaccgaga
    33121 aactggcttt tgaacaccgt ttatcaagag gttgtgacac gtcttttgtc acaacctctt
    33181 ttatttttgc ttcactgtaa ctgctacaat atcaccgatt tcttttccga tgtttttacg
    33241 aatatctttt cgtagtccaa ggatgtagca gactgaacca tctggatttt tcacgcccat
    33301 attcacgata ctgccttcat acggcacatt gtcaaaagtt gcttggactt taactcttcc
    33361 agcaccgaat tcttttctta tatcatacgg aaaaataata tatgccccgc ccttgccgac
    33421 ttcggaagca tagatttttg attcaaaaga ataaatttcc ctcattttat ttctcctatt
    33481 ttttacatct agtatagcat agcaaaaaaa agaaggaact gtgacaaaag tcttgtcgca
    33541 gttccttttt tcgaataaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatag
    33601 tcaacaaaca tgagaagctg ttttttgaaa ttgctccttg tgactcagag ttaaacggca
    33661 ggctcacaac ctcttcctta aacggtgttc aaaagcttgc atctacggca ctaagcccaa
    33721 tcagatgaaa aatatggagt gctattttta tctgattgtt cttactgctt gatgcagagc
    33781 agctttttca caacctccta catggtgttc aaaatattat tcgccttttg cttctttcac
    33841 taattttgcg aatgcttgtt gttggaattc agcagctaag gctttcgtac gttgttcttg
    33901 ctctgctttg ctcatttttg gattttcagt cattgctttt accataccgt cttgaacata
    33961 agcttttgct tcactttcca tcgtactttg ctgtttcttc actaattcag ctaacttggc
    34021 tgcttggtcc gtacttaatt ctacccatgt ctctgggatt ttgaatgtat tcactcggct
    34081 gtcatattcg tgattgttat cagcaatatt gaaccagaat ttatacatgt cgtttttgta
    34141 ttcccaataa gtagttttcg tcactttttc agcatcgccg tctgtctttt ctactttatt
    34201 tgtttcgtta tccgtaccag ttgcttttgg tttttcttgt ttttcatttg ttcggtaaag
    34261 atacactttt tcttttccat tccctaaagc tttatacaaa agcatatctg ctccttggga
    34321 atcagcactg gaaacaattt tttctgtttt tgtttccgtt actttttcca ttccaaagtg
    34381 attggacaaa ttagcgacga tcaaacttag tgaagcgacg aagattagtc cgaaaatcaa
    34441 agataaaaag gtttgccatg tttttttagc gaacacgttc gttaaagcaa aagcaagcaa
    34501 gctgacaatc aaaactccaa taatcatgca ttatcccccg ctttcattag aacaggttct
    34561 tttttcttca ataaaaaggc aataataaag ccaagaatcc caaagatgat cgctacgata
    34621 aacgcggcat ggtaacctga cagtgtggca ttgattgcct gatctttata agctaatggc
    34681 gtattatcca atacagattt gcttgggata tttgcttttg tcacattcgt caacacactg
    34741 atcaaaatag ctgtaccaat cgagcttgcg atttgacgga atgtattatt taccgctgtc
    34801 ccatgactga tcaagttatt tggcaatgca ttcataccag aagtcgttac cggcatcatg
    34861 accatggaga tcccaaacat acggatcgca taaaggatca cgatatataa aactggagtc
    34921 gtttttgtca agaaagcaaa tggtgcagtt gccgctgtca aaatgaacat ccctgtgatg
    34981 gctaaacgtt tcgcgccgta tttatcgaaa atcgcacccg tcacaggcat catagccccc
    35041 atgatcaatg cacccggcaa caacatcaag ccagaatgga atgctgattc tccacgaata
    35101 ttttgaatat acaatggtac gaccatttct gcccctacca tcgccatatt tgttacacca
    35161 gctaaaacag ctgcaatcgt gaatgtagat gatttgaata cacgaagttc caagaatgga
    35221 tgttccaaat gtaattgacg ccatgagaac aaggcgatga aaatcacacc aacaactaag
    35281 aaaccaatta ctttcaagct tccccagccg tcatctccta cactagaaaa tccgtaaagt
    35341 aaactaccga atccaatcgt tgataaaata gcggataaaa tatcaatgct aggatttgac
    35401 aatggaataa cacttttcat taggaagaat gctaaaacca agacaagaac aacgattggc
    35461 agtaccatac caaacaagtc acgccaatgg tagttatcaa tgatataacc agataatgta
    35521 gggcctaaag caggagcaag tccaataacg atccctgaca tccccattgc tgatcctctt
    35581 ttttctggcg ggaaaataga tagcatgata ttttgcaata atggcatcga tactcccaca
    35641 ccgcaagctt ggatcaaacg accgattagt aatgtactaa aattaggtgc tgtaaagcaa
    35701 gtaatcgttc cgatcaaaaa gatcgtcatg gcagaaagat ataaatttct tgaactgaat
    35761 ttattgatca gccatgctgt tattgggatc atgatcccgt tgactagcaa gaaaccagtc
    35821 gttaaccatt gcacatcaga cgctgaaata tcgaaagctt tcatcaatgt aggaaaagct
    35881 gtcgtcaata aggtctgatt caaaacggta caaaatgtac caattaataa gacaacaact
    35941 aaaagtgtcc gattatatgg ttttccgtaa atatctacgg gttggttgtt actcatattt
    36001 ctccttcttt ctgaattttt tctgaaacta ctagaatact ttagtcctaa attcgctatt
    36061 tgtcaaccta cttgacacat aagttaatac ggatataatt aagggaagca agaggacaaa
    36121 aggagtgaca aaaatggttg gggcttccct taaacgtttg ttggaaaatg atcaattggt
    36181 tgttggcatc agtgaattaa gtgatatcgt aggtgtgtct ccacgtcaat taaggtattg
    36241 ggaacaaaag ggattcattc gttcgatcga agctgatgcg aattgtccta gaaaatatcg
    36301 tttacctaca gtcataaaag tagaactgat caaaaaatat ttagatgacg gatttacttt
    36361 gtcaaaagct gcagaaaagg cagaaatccg ccaaaagaaa atgcaccatg tccgtaaagt
    36421 tttttcaaaa gcaatcaaag atatcgaatt gatcgacgaa cgctatacga ttttacaaat
    36481 cggtaacttc aaagaagaga atgctaagat gtacatcatt catgacaacg agacagacga
    36541 attaacttac aagctccttc ctgtcgatga aaaagctgac tacgaacagt tgttaaaaga
    36601 actctaaacg ccactaatct cctaagtacc aagcttttta ataagtagat gctacataaa
    36661 tacttgaaaa aaggcctgtt tgaacataag aatatccgaa cggtgatctg cgtttctttc
    36721 atatagaaag gaattctcca tcactgttcg gatatttttt tatttttttc ggttactttc
    36781 ttctaataca tctgttagcc aatttgcata ttctgtttcc cgattgatcg catgcgctaa
    36841 aatcaggtag tgtccgtaat tttcatgttt ttctttttca gtaggaaaga tcgttttttt
    36901 tcgctctaat agatgaagtc gtttttcttc atgaaggtca cgctgctgct gaataatttc
    36961 tactaatgcc ggatcattca cgtctttgac gaaatacaat ttcagaacaa attcgtctcg
    37021 attaaccggt agttcattgg tgggtgtatg aatccactct gccaattgtt ccttcccttc
    37081 ttctgttaat tcataaactt tcttttccaa tttttcacct gtgatctcta cttgatgctg
    37141 aatgattcct tgctcttcca tttttgcaag ttcaggataa atctgactat gttttgcttg
    37201 ccaaaattct cctatttcat ttttgaacga ttgattcaat tcatatcctg tcatcttctt
    37261 cttacttaat aaccctaaca aaatatatcg aagtgtattt tttcttgcca tcagttttcc
    37321 ctccttgaca aatctttaaa tccattctat cataaatgag taatcgaaaa catgtagttt
    37381 attacatgtt ttaatttata aggagatgct taaacatgaa agaatttaaa gaattggaag
    37441 attttattgg aactcacttt atctatacgt atgacaatgg ttgggaatat gaatggtatg
    37501 ccaaaaatga ccatactgtt gattaccgta tccatggcgg aatggtcaaa ggccgttggg
    37561 taaaagacca agaagctgat atcgttaaat tgacggacgg cgtattcaaa atcacttgga
    37621 cagagccaac agggacagac gtggcattgg actttatgcc aaatgaaaag aaacttcacg
    37681 gaatgatctt tttccctaaa tgggttgaag aacatccaga aatcactgtt actttccaaa
    37741 acgaacatat cgcagaaatg gaagcagctc gtgaaaaata tgaaacttat ccaaaattac
    37801 ttgttcctga atttgctacg atcacttata tgggtgatgc aggtatagac aatgaagatg
    37861 ttattagcga agaaccatac gatggaatgc cagatgatat ccgtagcgga aaatacttcg
    37921 atgaaaatta taaacgagta aaataaggtt gtgaaagaga ggttgtgaaa tcagcgttct
    37981 gacctgagta ttagagaaag aaacggaaaa atagttcctc atgttttgcc gttttttgag
    38041 ctaataccga gggtcagctg attgaacacc gtttatcaag aggttgtgaa atcagcgtta
    38101 tgctttgagt aataagaacg ctagttagaa aatagctttt catattttct aggctagtgg
    38161 gcttattacc gagaagcagc cgtttgaaca ccgtttatca agaggttgtg aaatcagcgt
    38221 tttgacctga gtattagaga aacaaatgga aaaatagttc ctcatatttt gccgtttttt
    38281 gagctaatac cgagggtcag ctgattgaac accgtttatc aaagattgta acaactgcat
    38341 attcacacag ttaaattagt gacttcaaaa tgaaataatg ctcccagcaa aaaattaggc
    38401 tgggagcatt atttcgttat tctgttcatc aaaaatcagc gttttgattc catttcatca
    38461 caagttcctc ctcatttact gcttcatctt tttgctgtgt ttgaattgta aaaccttgtg
    38521 aaagatagaa atgaatagct gattgatttt tttgatagac tgtcaaagtc agtgttttat
    38581 tggtttcttt tatttttttc attagttgcg taccgattct ttgttgccgg tattcccttt
    38641 tcacaaagat tcctgcgata aactgatcaa tcaccccagc aaaaccaata atttcttgat
    38701 ctatttctgc taagtaaatc actgcatctg gtaaagcttt cctaacagat tctacttgat
    38761 tctcccaata agttgatgga atgaattcat gagaatccaa gttagcatgc agccaaatcg
    38821 atagaacaga ttccagttct ttggcagaca attttgttgt tgtgcggatc attttttctc
    38881 tccttactta ttcattgatt ttaaaataaa aaccattttt ttgaagctct tttacaagtt
    38941 ttcgcccctc aaaaaagtat atcttctctt gttttacttt tctaatacca aaagaaacag
    39001 caactttagg atcatcagct gaaacgattc gataagttcc accaggcaat tgatccagct
    39061 tgactttccc atgatggtcg ctttgtactg aaaacggcac accatttcta gtaagtgttt
    39121 ttttcttatg tttcaaaatg aatgaactac catttaccgg tttccctgac gaatcactaa
    39181 taataaatga aaaatcaagc acttttttac ttaatctata ctgatagatt agtcgtccga
    39241 taaacactaa cagtatgact acagctatta tcgttcctgc aagaataaac cattgccgca
    39301 tggttctttc ctgatttcct tttccttctt ctttttttac cgattcgtta taaggaatcc
    39361 gatgtcctgt cactagcaaa cgatgcgtgt tgatcatata cggcgtacat gtaagcaagg
    39421 taactaagtc ttctccttct gaaatcgtta gaacagacgt gtcatctggc agtaccactt
    39481 gtatattttt aacttgataa gccaatttct cccccaaaac agtcaaaata aacgtgtctc
    39541 cgttttctaa acgatctaat tcggtaaata accgtcgatt aggtaaaccg ctgtgagcag
    39601 agatcactga atgcgtcgaa tttccaccaa gcgggaaaga ggttccttgc aagacgcctg
    39661 ctccattttc aaggatccta ccattgagcc gatcataaag tgaaatattt aattggatct
    39721 taggtatatt gatacttccg atcagccatt cctctaattg gctggatgtt gtactttcat
    39781 ttctgttctt ttcattgaaa ggatcagtac caggattgaa tccttggtca gttaatcgtt
    39841 ggtttttctc ctccattttc tttcgctgca cttcaatttc agctgcggtc cgtttttgta
    39901 cttgttcgat acgtttttga tcaataaaac tatttaaaga atccacataa aatggatata
    39961 aagcgatcag taaccctacg acgatacata ttaataaaaa caaacgaaac aaaagtcgac
    40021 gagactgttt ttgcttactc tgcttcacat gtgtcctccc ttgcaagttt ttttgttctt
    40081 tcttttatta tatgggttca ggaaaaaaat agaaaatgaa agccgatgag gttgtgaaaa
    40141 agctgtcctg catcaagtaa taagtacagc ccaaaaaaat agctactcat attttttgtt
    40201 gggttgggct tattaccgca gatgcaagct tttgaacacc gtttaaggaa gaggttgtga
    40261 aaactgcgtt atgctttgag taataagagc gctagtcaga aaatagcttc tcatattttc
    40321 taggctagtg agcttattac cgagaagcag ctgattgaac accgtttacc gagaggtcat
    40381 gaaaaagcta ctttgtttcg agtattaaga aaaattctgt ttcaaaacaa ggagatgcaa
    40441 caaaacttat gtcgcatcct ctctccttag aactttcact tatgtttttc ttgtaaaatt
    40501 cataaatatt ttcatgaatt ttctaatttc ttgcctacct ctcgcatagg atatatgatg
    40561 aatttatcta aagtttgcaa aggagttcga caattgaaaa aatatggccc atttttagca
    40621 atttttttca ttgctttggc atttctcatg cctcatttat tcacacataa actaattttg
    40681 ggtgctgatg ccccattcca ttacaatcgg ttctatgatg ccgcgcaaca aattaaatat
    40741 ggggatttcc attattttcc ttccctttat ggattccagc aaagtggcag gatcgtgaat
    40801 gccgtttacg gcccattttt cgcttattta caaggattga tcgtgttgct tgcaggtagc
    40861 tggtttcatt atcagattct ttcaaatttc attctttatc ttatttcagg attttctatg
    40921 ctgattttac tgagatatgt caatgttcga aattgggtaa gtgtaccagt agccgtttta
    40981 ttcatgagta cgtattctat tcaatactgg tctatcaacc aaggattcac tagctggggg
    41041 acttgttttt atcctttatg tatgatccct attgctgatt tcgtccttca taaaaagttc
    41101 cctgttatca aagtcgctgt ctcagtggga cttatgacac agatccattt actgtcttcg
    41161 atcatgttag ctttgatgta tatccctttt tatctttatt acttttttaa ccagactgaa
    41221 aaaggaaaag cactgcttca actgattaag tcggtcttgc tttattttgt tctgacagca
    41281 aatatttggg caggattagc tattgtttac agtgggaata agattcttcc tccctttgtt
    41341 aacagagaaa tgagtcaaaa ggcgatagat ctggatggca gttattggct ccattaccct
    41401 aaggcctttc ctatattgat attatcaggt tttttgcttt ttattttctt tcaacaaaag
    41461 aacaccttat tccaaaaaat cgtgttgtac acaagtcttg ttttcttttt tctttctact
    41521 agcttgattc catggacgac attgatcgaa aaaaatgtgc cttttattag tttgatccag
    41581 tttccatttc gatttttcgt gccatttacg ctattgcttc tactttacct tgccctttca
    41641 ctgaaccagt ggtctgaaca aaagtggttc cgtcttttaa gtatatttgg cattcttatt
    41701 ttttcagcac agacgatcca gaacttatac cagcatctgg aaaagtggga aaatgaaaca
    41761 tttgtcagtc gacatactta tctattcgat acgccggaag aagcaaggaa aacattcttc
    41821 agcaaagata tgtctaccag cttgttcgtt ttccaaaaaa ccacacctga ctatctgcca
    41881 atctataagg agacaaaaga caataaatac gaccggtata acgaagaaat actagaaaac
    41941 gaaacaactt ttataaaaac acatccaggc ggtcttttga caatcaagtg gaaaaacact
    42001 ggggacaaaa ctgttcatat ccctgttatc gtctacgatc ggactgtgct acagcaaaat
    42061 ggaaaaacat tgactgatta tgaagtaaca gatatcggga ccccaatcgt gaagcagcaa
    42121 aaaggaatca acgagctcac gcttcattat caaacgccaa tctatttcta tttcattctt
    42181 tctcttactt tgattggctg gtttaccttg ctatgtttat ttatttatca tagatacaag
    42241 cttttacgtg cttaggcaaa agggataaat acatccgatc aaaaaactct ccaaacggta
    42301 taatcgtttg gagagtttta ttttaatcag tttttttatg ttatatgtta tattttttat
    42361 tcgttcacat ctaattcgat ttccaccccg tagtgatcac tgatgattgg actatcgatc
    42421 ccatcaaaaa tccgttgata ttttttaacc tgcattcctt cagggacgaa aataaaatct
    42481 atacgcaatt tttctgtatt ttgttcccaa ccatctattt tcttttccac agtagctgct
    42541 tttccttttt cattcgcgac aacatacgaa tcttgaagaa gaaggcaact ttctcttaca
    42601 gtataataac cttgagagtc tactggatta ttgaaatcac ctaggaaaaa aagtggtacg
    42661 cgagtttcca aaaagtagtt ttccaagttt ttccactcaa aataaaagcc acttttttta
    42721 tctgtccacc aagaaaagtg gcagctcgag acaaaaatgt cctgatcatc tatctttgtt
    42781 ttcccaatca agatcttgcg tgtctgataa tcttctttct tttgaaattg ggagacggta
    42841 aggacctgac tttccaatgt ttttttcgta agcagtgcat ttccttcttc atatttatca
    42901 taaccgatgt ggctcatttc ccaactccaa aaatactctt ttccgtgttc ctttaaaagc
    42961 tgaactaaac ggtaggcaaa attatcttta cggataggta cttgattctt taccggacag
    43021 aacttcatta gcttcgcagg ttctacttct tcagattcca gtaattggtt gatttcttgt
    43081 aaagcaatca cttcataatc ttctaacagg atcttatctg ctaattcttg caattttttc
    43141 tctggttctg gctcaagcca gctatgcgtg ttgagtgtca tgaatttcat tggttttctc
    43201 cttgtcttca tttcgaaaca aaagggttgt gacaaaattt ttgtcacaac ctctccagca
    43261 aatagtgttc tcctgctaac tcctcagtaa taagctcaat ggaccaggag ctattttttg
    43321 tttggctgtt tttatcactt ggtgcagggc agctttttca cgacctctcc actaaacagt
    43381 attcaaactg ctgcttctcg gtaataagcc caaccaaacg aaaaatagga ggagctattt
    43441 ttgtttggct gttcttatga cttgatgcag gacagctttt tcacaacctc tccttacatt
    43501 ttaatggagc cgatcacttt accagctgtc actgtaccta attgcttgat cactacttct
    43561 tctactttat cgtttgtaaa tacgatcatg atcgttggat ctttttcttc gttttggatc
    43621 acatcaagat ccatctcagc taatttcgtt cctgttccta cttcttggcc ttctttgaca
    43681 gcaatctcaa aagctggctg attcatttgg actgtatcga ttcccatatg gatcaaaact
    43741 tcgataccat ctttcgtttc cagcccaatt gcatgtttgc tagggaaaat acttgtcact
    43801 tttccagcga tcggcgcaac aacttctctt gatgttggaa taacagcaaa gccgtcaccc
    43861 atcatttttt gtgagaatac cggatctttt acttcagata aaggaatcac ttctccagaa
    43921 gctgcggaaa ctagttcttg ttctatacct aagtattgct tactacctgc ttgtccattt
    43981 cctgtagaaa ccatttctgg ctctggaatc tctgctcctg attgcagcag atcttcgata
    44041 tctgatttca agacatctgc ttttggtcca taaactgctt ggactccatt gtctttgacg
    44101 atcaatccca tcgcccctgc tcgtttccag gcttcttcag tccctacttt ttctcgatca
    44161 tttacactta cgcgtaaccg agtcatacaa gcatcgacat ctttgatatt ttcttttcct
    44221 cccagcaaat gaatgatctg gaccacttgc tgatctgctg ttcctgttcc gctgttagat
    44281 acaacggttt cttcactgtc attgtcgtaa tttccgttac gtcccggtgt agcaaagttg
    44341 aattttttga tcaagaaatt tgctaagaaa tacgtaacaa caccaaaagc gatcacacac
    44401 aacacgaagt tgataagatc tccacctaga cccgctttga tagctaacgg tgtccgagtc
    44461 agcaattcga tattcccaaa tgaatggacc cgcaatggca agatatctgc catcgcaaat
    44521 gcagcccctt ggatcactga ataaatgaca tataatggca cagcagcaaa cataaacatg
    44581 aactccaatg gttctgttac acctgttaga aagacagcca acgctgctga aaaatacatt
    44641 gatttatatc ttgctttctt atcaggatcg acattacgat acatcgcaaa agccattccc
    44701 atcaagatac ctgaagaacc aatcatttgt cctactttga aacgagccgg cgtccagtta
    44761 tgcaacacaa actcatattg cgacatatcc cctgcacctt taagattcac taaatcagtg
    44821 gcccaagcca accataacgg atcttgccca aatacttgtg tccccgcctg tgcgcctgat
    44881 aaaatctcat acgatccgcc aagctgtgta tagttgatag gaatcgtcag catatgatgc
    44941 aatccaaatg gcaatagtaa acgttctaat gttccaaata aaaacggtgc tagaatcggt
    45001 gcgctttctt gtgattctgc aatccataaa ccaaaattat tgattccagc ctgtacgttt
    45061 ggccacacca cagcaagaat caatgccacg attgttgacc ataagataac aacaaacgga
    45121 acaaagcgct ttccattgaa aaatgacaaa gcatccggca attttctata attatagtac
    45181 ttattataag ccattgcccc gacaaatcca gcgatgatcc ctacgaatac tcccatattc
    45241 aaagctggtg cttccaatac acttgtaaaa aatcctttaa ccatgatctt cgtaccgaac
    45301 agagtgtggg taaatgcatc ttcattcgca agcatgtcac ttgtgacacc aaagatagcc
    45361 ccagtgatcc gattgattaa aataaatgag atcccagctg caaatgctcc gcctgctctt
    45421 tcttttgccc aacttcctcc tattgctaaa gcaaataaaa tatgaagatt accaataatt
    45481 gcccaaccaa tattttcaat tactccgccc gttgtgacaa gcggcgtcca atcaggattg
    45541 atcaagggaa ttgatttccc tatactgatc atcaacccag ctgccggcat aactgctacc
    45601 acaaccatta aagcctttcc aaatttttgc caaaactcaa aactaaatat ctttttcatt
    45661 ccgtttagct cctttacgca atcggtttcg ttaaacgtat tatagcgtgc gttttctttt
    45721 ttgtaaatgc tttatttttt atttttctgt ctataccatt ctataaaacc tataatacgt
    45781 gtgttccctt ctataatttt ctcctaaaaa tttatttttt taagcttttt tctatgaaat
    45841 attttctttt gtctattgac ttgtgcaatc ggttgcgttt attatgaacg tataaaacag
    45901 ctcattagga ggagaaaaat gaaacagatc aaacgactat ttgctattga tccatggaaa
    45961 atcagcacga cacaattaga taaaaaaaat cttcgactgc aagaatcttt aacaagtatt
    46021 ggaaacggtt atatggggat gcgcgggaac tttgaagaaa cttactcagg ggaccaccat
    46081 caaggtactt atttggcggg tgtctggtat cccgataaga cacgtgtcgg ctggtggaaa
    46141 aatggttatc cagaatactt tggaaaagtg atcaacgcct tgaactttat cgcgatagat
    46201 atttcgatca acgatcagct gatcgacttg gcttctttgg aaccagaaga cttttactgg
    46261 gaattagata tgaaaaatgg tgtattatct cgtacattca caatcactac ttctactaat
    46321 aaagtacgca tttccttcga acgttttctg agcattgtca aaaaagaatc agcttatatc
    46381 tatttaacta tagaaatgct tgaaggtagc ggaacagtca aactcgtatc aaaattggat
    46441 ggaaatgttc aaaacgaaga cagcaactat gatgaacatt tttggaatga gattgatcgt
    46501 ggaactatag aagaaatcgg ctatttgacg actaaaacta ttccaaacaa ctttgggatt
    46561 gaacaattta ctgttactgc agcaatgcgc catttcgtta atggaaaatc agtcatccct
    46621 gactatcacg aagatacttt agcattacat ggttgcttgt ctgcagaatt atctcaaggt
    46681 gagacatggt cagtggaaaa agaaattatc gttcttacta gtagagatat tccagaagcg
    46741 cagcaagcag aaaaagctgt ctcagaatta acgaaccaga caaacaatta tatccaagca
    46801 aaagaagagc aaacagcggc ttgggcagaa cgatggaagc ttgccgatgt ggtcatcgaa
    46861 ggagacgaag aagcacaaca aggtattcga ttcaatttgt tccaactatt ctctacttac
    46921 tacggcgaag atgaacgatt gaatatcggc cccaaaggat tcacaggaga aaaatacggc
    46981 ggagccactt actgggatac agaagcgtat gctgtccctc tttatcttgc tttagccaaa
    47041 cctgaagtaa ctaagaatct gctgaaatat cggcataatc aactgccgca agcaatccac
    47101 aacgctcagc aacaaggatt aaaaggcgcg ctttatccta tggtcacctt cactggtgtc
    47161 gaatgccata acgagtggga aatcacattc gaggagattc accgaaatgg cgcgattgcc
    47221 tatgcaatct acaattatac gaattacacc ggcgatacgg aatatttgaa aaatgaagga
    47281 ctggaagttt tagcagaaat cgcacgcttc tgggcagacc gtgtccattt ttcaaaacga
    47341 gcaaataaat acatgatcca cggtgtgacc ggcccaaacg aatatgagaa caatatcaat
    47401 aacaattggt atacaaatac gatcgcagct tgggtcttgc gttacacgcg agaaaattat
    47461 ttaacttatc aaaaagaagc tgctatcact atcagcgaag aagaactagc caaatggaaa
    47521 gatatcgcag agaacatgta cttcccagtt gacgaagaat taggaatctt tgtccagcat
    47581 gacacattct tagataaaga tctcatgcct gtatccgata ttcccacaag cgatcttcct
    47641 ctgaatcagc attggtcttg ggacaaaatc cttagatctt gcttcatcaa gcaggcagat
    47701 gtactacagg ggatttattt cttcaatgat acttttacaa aagaagaaaa gcaaaaaaac
    47761 tttgatttct atgaaccaat gactgtccat gagtcttccc tttcgccaag tatccattcg
    47821 attttagcag cagaattagg aatggaaagc aaagctgtag aaatgtacca gcgaacagct
    47881 cgcttggatt tggataatta caataacgac acagaagacg gcttgcacat cacttccatg
    47941 actggtagct ggttgtcgat tgtccaagga tttgctcaaa tgaaaactgc ccatgatcag
    48001 ttgagattcg caccatttct gccaaaaact tggaaagctt attctttcca tatcaattat
    48061 cgcggacgtt tattgttcat ctcagtcaca gatgaacaag ttactttcga gttattagaa
    48121 ggttctcctc tagaaattta cgtctatgaa cagtcttatt ctttagcgga tcgtctagaa
    48181 ataacgctaa gaaaggagga agcaaatgtt taaaggggta ttgtttgatt tagacggtgt
    48241 cattaccgat actgctgaat tccattatcg tgcttggcga aagcttggtc aggaaatcgg
    48301 cattacgatc gaccacacat tcaacgaaca gctaaaaggc gtcagccgag aagactcact
    48361 ctctttgctt ttagcttatg gcggaaaaga acactctttt tcaaaggaag aatttgcaga
    48421 attagcgaaa agaaaaaacg attattattt agagatgatc cagacgatcg aaccaaaaga
    48481 tgtcttcccc ggggtcgtgc ctttactgga ttctttaaaa gaagaaaaaa tcaagattgc
    48541 tcttgcttct gcaagtaaaa acgggccatt cctacttgaa aaaatgggtc ttacacctta
    48601 ctttgatgct attgccgacc cggcagaagc aacaaacgga aaacctgcgc cagatatctt
    48661 cctccttgca gcaaaagctg tcggactaaa agcagaagaa tgtatcggga tcgaagacgc
    48721 gcaagccggt atccaagcca tcctctcaag tggcgctcaa ccaattggcg tgggacgtgc
    48781 tgaagacctt ggagaggaga tcccgcttgt ccctgatacg acttttctta cgatcgatta
    48841 cttgaaagaa aagtggcatg accatggata atccagagat ctccgtcgta ccagttccag
    48901 agactgaaat aaagaaaatc acattgaaga acgactactt agaagtcgtt cttctcaatt
    48961 acggtgcccg cctgcaccaa atcttcgcac cagacaaaga aggaaaatca gaaaatgttt
    49021 tattgtctta cgatcgtttc gaagatgttc taacagacaa aagctttttt ggagcaactg
    49081 tcggacctgt agccggaagg atccgggatg cttcttgggg tgagcataga ttggagaaaa
    49141 actgcggatc acaccatatc cacggtggca cgaaaggctg gtctttccaa ttttgggaag
    49201 tagaagtttt caaaactcca tcatcaatag gtgtggtctt ttacttaaaa gatgaatttt
    49261 ctacctatcc aggaccaatc actgctacga tcacttaccg tttaacaaaa aacgaattag
    49321 agatgacaac ctctgctagt agccttgttg aaaccatctg caatccgacc aaccatgcct
    49381 acttcaacct ttcaggaaat ggaacaagag acatctatga acatcagtta acggtctttt
    49441 tagatggtgt gcttgaatta gatcaagaaa aactgcctac tggaaattgg acaaaaaaag
    49501 aaaaactgcc aatcgacttt agaaaatccc caacactgca agagatcctt gcatgttatc
    49561 cagatggact agatgatgta tttcttttgc atcatcctag gctttccaaa acttccttac
    49621 aattattcga gaagcattct ggtcgccaaa tgactatagc aacttctaat aaaagtatgg
    49681 tattattttc tacgactgga ttcgaagctg atttctctgt caatggaaaa cagatgcatt
    49741 caaactacgg attagcaatc gaaccgcaag aaatccctga tatcgttcat ttccccaaat
    49801 ttggatcgat caacctccat cctggtcaag aacggatcag tcagacgatt tatcggttct
    49861 ctgcacaata acaagagaaa ggtgttttta tcatggctat taccgtaaaa gatgtggcga
    49921 aaaaagccgg tgttgccacc tcgaccgtct ctcgtgtcat caacgatcat cctagtattt
    49981 ccgagacaac aaagaagaaa gtccgaaaaa ttatggatga actaggttat gttcctaaca
    50041 tgactgcccg caatctagga aaacgcattt ccagtgccat cggcgtaatc ttaccccctc
    50101 ttgattcaaa agagcggatc ggtaacccat tttatcttga gatcatggaa gcaatcaacg
    50161 aagaagcgcg gaattatgat atgactacag caatcgctac tgctaaaaat tttgaattgc
    50221 tgttagagaa cgtccagcgt atgcatttac aaaaacaagt agatggtttt attctagtgt
    50281 attcagatag tcaagatact gtcattgatt atttatacca aaaccacatc cctttcactt
    50341 tgatcggaca gccttatcat catgagaacg aaatcgttta tgtagataat gataaccagc
    50401 ttctaggtaa acaagcaaca gaatttttga tccagaatgg acataagaat atcctgtttg
    50461 tgacaaacac gactcatgaa agtttgtatt tcgaacgata tttcggttat caaaaagcaa
    50521 tgatgatggc tggtcttcct gcgttatcca gtgtagtact agagcatccg gaggattatc
    50581 tgtcctttga gaaaacgttg aaagaaaacg aagccacagc attggtggtc attgacgata
    50641 tcttcgccct tcgcacgatg cagttggcgc aaatgtatgg ctatgtcatt ccagagacac
    50701 tctccgtcat tagcttcaac aactcgatct tctcaacatt aacacaccct taccttacaa
    50761 gtatcgatat cgatatctcc gaattaggac gtgtcgctat gcaaaagctg cgcgaattga
    50821 tccatgaaga attgagcagt ggcgtacgtt tggtcatccc tcatcgcttg atcaaaagag
    50881 agacagtcgt tcctttagaa aacccatact aaatagctga ctcactaaat acgctgacca
    50941 tttatcctat ggtcagcttt ttatgtaaaa gaagatacta cttctaacac attgtttatc
    51001 tgtaaaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    51061 taaacggcgg aagcagaagc aactccttcg gaaataagct gaaattcaca aaaatttaaa
    51121 aagcaatttt cttgagtttc ttcttatttc ttggagttaa acgcttctgt cccagcctct
    51181 tttttccttc cttcaatttt ttacacgtcg acgattcaat aaaaaaccgc ctaatattgt
    51241 aaagacaggt gcaagaatcg agaaaaaggc gaatggcaag taatgcaacg cgctaacttt
    51301 catcgttccc ataatgaatg tgccgctgac tccccacggt acgagagaat tgacggtcgc
    51361 acctgaatcc gctagtgttc gtgtcaaata ggtttttgat aagccaacgt catcaaaaga
    51421 acgcttgaat gtttctcctg gaagaatgat ggacagatac tgttctccaa cgatcagatt
    51481 gattccgata cagctcaagg cagtaaaccc gactaaacga gaaggtcggt ccatcttttc
    51541 ttttaattct tgaacgatgg tatcaacgat cagatatttg atcagtaacc cacctaatgc
    51601 caatgcaagt aaaatcaaac tagcagaacc taacatactc atgatcccgc ctcgagaaag
    51661 cagttcatct agctttggat caggtgtatt tgcgacataa ccattcatca agatgtctgc
    51721 tgcttttccg accgtcaaac ttttctcatg gataaaagaa agaacgagag cagctgtcga
    51781 tcccgctagt aatgtaggga tagccggaat ttttttgatt gcccccccaa ataaaataac
    51841 tagtggaatc aatgtccaag gagagatcca aaagctcgct ttcatgtttt ggatcatttc
    51901 attgatacta gctagatcgg ctgaatgact gttatgtcct aatatcgtat aaaaaatcaa
    51961 cgaaaggacg aatgctggga aatccgtata acgcatacca gcgatatgtt cgaatagatt
    52021 aactcctcca atacccgctg ccaagttggt cgtatctgat aaaggcgagc agttattccc
    52081 taaaaaggca ccggaaacga ctgcgcctgt agtcattgca tcattgaatc caagtaaatg
    52141 accgatcccc aaaaaagcaa ttccaatcgt cgaaatcgtt gtaaatgaac tgccgacagt
    52201 cactccgaca attgcacaaa caagaaatgc tgtcggtaaa aagaaacgca cagaaacaag
    52261 tttaaatcca taaaccataa tcgtagggat ggttccagat aaaatccatg aagcaactaa
    52321 gacaccaatc aaaagaaaaa tcaggattgg aatgatccct ggagtgattc ctttgatgat
    52381 cccgtcatgg atctcatccc atgtgaactt tttaaatctg ccataaaaca acaaacacat
    52441 gaaagctgca aggatcggga tatgtggcga gagctggaat ccgatgatca gtactcctag
    52501 gagtgccaac aacacgatca atacagcgat actttctttt aaagaaatat ttttattcat
    52561 cgtcgatctc ctatttcaaa tgaaaaggcc ctgccatgaa aaaactattc acttggcagg
    52621 acctcctact aaatcagcga caaaacgtcg gctgaaagac ttattttttt atttttcttc
    52681 taaacttttt tctacctcaa tcccccaaga atctttcttg aagtgattga tgatcaatgg
    52741 aataacgaac atgaccactg tgatagctgc tactaataat gcatcactca atgtcgctgt
    52801 acctaatgta gcaaatacga caacgatgat agagaagatc agcatgcagc tgactaccca
    52861 agctaatccg tttccgtttt taccaattcg gtaaggacgt tcgaattctg gatgtttctt
    52921 acgcatttta agcaatgaaa cagcaatcaa aatgtacacg atacaataaa taacagttgt
    52981 agcatttgta agtgtcaaga atacagcact tacgtcatcc attacaccat aaagcaaagc
    53041 aaataatgaa ataacgattg attgtgttag aacgacattt ctagatacgc cgtatttgtt
    53101 ttctttatgg aatccgaatt ttggtggaag gaatccttca cgagctactt ggatgattgt
    53161 ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc acaccaataa ataccatgaa
    53221 gctgaagata tttccgatca cttctggtaa gcctaggatt tgacagtcaa tcaagatagg
    53281 ctgcgtgata tttgctaatt ccatttttcc atctggtacg acatttgcta caagcatcgc
    53341 attgatgaca ttcaataaaa ctaatccgat caaagcgata aatacgcctt ttgtataatt
    53401 ttttgttgcg tctttcaaac gaggcatgta aacagaactc atttcgatcc caacaaaaat
    53461 aaatgtgata ccagctaagt atttcaatga atcaatatgt tccaagtcag ggaaagcttt
    53521 tgaccatgaa aagtcaccta gatagccgtt tgagactagt ccgactttga aggctgccaa
    53581 aacacctaaa acgaacatga tgactactgg gatatatacc cctagccata caccgatgtt
    53641 cccgccgact tttgccatat cgaatttcaa gttcaagatc gtgatgatcc agtagataac
    53701 taaaatacaa cctaaaacga accagtgatt attgccaagt tctacattac caaatgtgtt
    53761 tcctaacaat ggtcctaaag tagaagcgac cattaccata cctgggaaca tttgcaccca
    53821 taatagccat gcaacgacaa atccccattt gctgcccagt gctgttttta cccataactg
    53881 aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg gaaaccattg atatcggacc
    53941 ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat gtccaaccga ctgcggctaa
    54001 cgtaggaata ctccgaaccg ttgcacacag tgccattgtc agaccgataa aggtcccaag
    54061 acccatttta cttacttcag atttactcac cgttgacact ctccttgatt ttttggataa
    54121 aataacggtg tctttgaagt agtttcagca ataaacgaaa caattcagcg aatatttgag
    54181 gggattcttt gagtttattg cttgaagggt ttcttcaaag acaacctcaa aacaaaggga
    54241 tcgaagagct taggtctccc cttgctcttc agatccaaac atgcgtcaga aacagttagt
    54301 attcaagctg ttttctaaca tgattacctt gcttattttg cttcgcttgc caataattgg
    54361 tctgcgtaga ttttttccaa tttttcttga agagctgctt tgattttttc agcatattct
    54421 tcaaagtgtt cttctttgtt catgtatggt gtcattacgc tggcacgcaa tacagttact
    54481 tttccggcac ggttccattc ttcatctgag aatcctagtt ggttcacaaa ttgtaatggg
    54541 ctgttgccat agtctgggat agcaaagtca gtatgtgaag ttaagaactc attaccgtaa
    54601 atgcttcctt tcacgtatga agaataatca tatacgtcat ggttcaattt attcattgca
    54661 actaagtcat cgttgccttt ttctttgaat acatagtcta ccatattgaa atctggataa
    54721 gttaatggat gaacttcgat ttctttgtct cctactttaa atgacaagtc attcaagaag
    54781 ttgtagaaac gatgtgcacc ttcgattgat gcacccatta atttaccata tcctgtgaca
    54841 ttcaaaggta agacatggtg tgctgcccaa acgctggctg ctgttgcccc tgcttttgaa
    54901 ccttccaaga tataagcccc aagtaatgct gggatatctg cgcctttttc aaatacatat
    54961 gtcgcaaagt aagagataac gtctctcatg cggatatctt tgatgacgat accaccggca
    55021 gaatatggaa catagcccat tttatgtggg tcaatcgtta cagattctgc ttcttcgatt
    55081 gctttatatg cactgtgtac ttcttctaag atataatctt tgttttctgt aaagacattg
    55141 tatttgtaat gaacatcttt taaatcttca aatggaatga agttgttgtc ttcgtctaag
    55201 aaaatcgcac ggccgtatcc gccataagca gcatctacgt gtaagtagaa gtaaataccg
    55261 tctttttcta atacgcgacg caatgcaacg attttatcga taccgtcgat tgctccttct
    55321 tctgttgatc ctacaacacc gactacacct aggattggtg ttttttcagc tgctagacca
    55381 cgaacgattt tttcaagttc gttgatgtcc atgcgatagt tgtggtcaac tggcactgga
    55441 atcacttggt ctaaaccgat accgatgatg tcggcagctt ttagccatga atagtgttta
    55501 gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt ttccgctacg tgctgagtga
    55561 gctttgattt cgtcgatttt ttctgggacg ctgtctaaca gattcatgat ttcttctgtt
    55621 gacaagttca ttaattccca atcgcttttt ccagcaacta gttcaggtgt cacttctttc
    55681 attgcaagcg gcaatgattt gatgttgcgg gcataccaaa gtccttctaa gtttgctaaa
    55741 gaaccatcag caacgatgtg gccccagcca tctttatagc tcattaattt tgcaaattcc
    55801 attcctactt cttcttccat ttggcttgtt gcaggagaag attcataggc aacgttatta
    55861 ccattccata gcatagcaaa attgtacgct agtaaagatg gcatcaatgt ttcagagttc
    55921 atatgacccc agtaacgtcc ggcattatgc caaggaacgg aatgggtacg catccgcgct
    55981 gaaatttctg atagaacatc ctttgtttta ttcacagtgt gttcaaaact agcactgctt
    56041 ttttcttctg gcgtaataat aggcatgtct tgaggcatgt agttttgacg ccagcctaaa
    56101 tgttcatcca ccaattcatt caacaaagct ttatagattt ggccgttctc agctttgtcc
    56161 ccaatgaata gggcatttag gtttagatct ttcgacaatg attcactcat agtgaaaccc
    56221 tcctaaaaaa atatttaaat tttgtcgagc cctacattac acctgttctt ctattctgta
    56281 aactaagttt tggcctgatt tttaatcata ttttaatatg tatcaattat ccgaattgtt
    56341 cacacttttg aaataattaa aaaaaacgag ggaatttaca aatgtaaact ccctcgcaaa
    56401 gattgtatta acgacaacca gcgttctatt ttaggatggg tttcaaaatt ggaatgttgt
    56461 aatagtattt ccctttttca aggtaaaaac ttactaaatt ctaatcaatt actttggcca
    56521 aaaagtaatt tttcttacct tttcgaataa ccacaaactt accatcgaat tcatcggatg
    56581 gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt aatacttata gctccgtttg
    56641 aaacatcttc acgtgcttga cgtttagatg gttcaatttt tgtggaaaca agcagttcca
    56701 cgatattttc aggtgtgctt gaaatttcaa cgttcggcat tttaccgaat ccttgcgcga
    56761 tttcttccgc atttagttct ttaatatttc cagagaacaa tgcttgcgtt attttttgcg
    56821 cttctttcaa gtcttcttca ctatgcacaa atcttgtaac ttcttctgcc aaacggcgtt
    56881 gtgcttcacg tttctcaggt tctgtctcta cttttttcgc taagtcttcg atttcttctt
    56941 gagacaagaa agtaaagaat ttcaagtatt tcactacatc gcgatcatct tgattcaacc
    57001 agaattggta gaactcaaat ggtgaagttt tcttcggatc aagccaaacg gcaccgcctg
    57061 cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa tgggatcgtt aaaccgaacg
    57121 cttctgcttc tggtccttct aattttcgga ttaggtctaa tccagctgtg atatttcccc
    57181 attggtctgc tccaccgatt tgcaattgca catcgtatgt tttatgcaga tgcaaaaagt
    57241 cgatagattg caggatttgg taagtaaact ctgtaaatga gattcctact tccaaacggc
    57301 tggcaacgat atcttttgct aacatcgtgt tgatgttgaa gtttttaccg tagtctctca
    57361 aaaattcaag taaagagatt tttgacaacc agtcgtagtt gttcacaaat gtgatatttg
    57421 catctttacc aaacaatttt ctcatttgat tggaaagtgc gtccacgtta tgttgcactt
    57481 gttccatcgt ttgcaacaca cgttctgttt tgcggccgct tgggtcgccg atcgttcctg
    57541 ttccgccgcc aatcagaata tatggatgat ggcctgccaa ttggaatctt ttcatcatca
    57601 taaatggaat caaatgtccg atatgcatcg aatcaccagt tggatcaacg ccgcaataaa
    57661 gtgaaatgct cttttcttca acgagctcgc gaagtctttc ttcgtttgtt tgctgattaa
    57721 tggcgtcgcg ccaagttaat tcatcaataa tattcatttt actgacctcc gtgtagtttt
    57781 tttatgaaag caggaacctg ctagcatatg taattaatta tttcttcagg ataggatagg
    57841 aaataaaaaa agtcccttgg catataagcc aagggacgaa atctcgcggt accacccaat
    57901 ttgtatgtct agatatccaa catacctctc gaacatttaa cgctgtcgcg tggcaatcac
    57961 tgccaaagac tcctgaaatg taattcgctt taaagcatgt actggtttgc agcgaccacc
    58021 agctttctga aacattggct ttaacaacta cttcgtttcg atcttcgtct tgttattatt
    58081 aatatgtgtc tatcatagag cgcaactttt tctttgtcaa cagaaaaagg atattttttt
    58141 taaattcctc attttttctt ttttgaatcc gctctaattc cgaacatttt attttcaatt
    58201 attgttaaaa gaaataactt tttctgtatt ttttctgcaa tttatcgaga agtcacttta
    58261 ctttgcctct tattctttct tcgttacaat aaggaatggg acaagtaaaa aaatgaaaaa
    58321 gcaagggacg aggtatatgg aaaaaaagca aaaaattatt ttaggagcca cttctgcttt
    58381 aactatcgtt attttaattc taagtttgtt ttttgtcatc cgatcatcta caaaaaaaga
    58441 accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa gaaccgacag atgataagca
    58501 acaactagtt actcaagcaa aaaatctggc tcaaagctac gattatgacc aagcgattgc
    58561 gttattggaa aaagatagta agaacggatc tactgaaaca caacagcttc ttcaaacact
    58621 aaaaaaggag aaagaacaac tgatcgactg gtctgatcct actcagatct ctcatgtctt
    58681 tttccacagc ttgatcgtgg acccgcaaaa agccttccac tctcaacagg cacaaggata
    58741 caaagattat atggtgactg ttgaagaatt caaccgttcg atcgaacaac tttatcaaaa
    58801 tgattttgtt ttagttaatt tgaatgattt gatccaaaaa gacgaacaag gaaatctttc
    58861 ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg gttctttcac aagatgatgt
    58921 cagctattat gaatatatgg ataattccgg ttttcctagc cgattggtcg tatcaaataa
    58981 caatgaaatc aaaaatgtct ataaagagaa agataaagaa gaaatcggtg actttgacat
    59041 ggttcctctg atcgatgcct ttgtcaagaa acatcctgat ttttcttatc gaggcgcaaa
    59101 aggtaccttg gccctgacag gttacaacgg agttttaggt tatcgaacat caaaatctca
    59161 atatggagac aatgaaaaaa caaaaaaaga gattaaagaa gctaaaaaag tggcggaaca
    59221 gttgaagaaa gacggctgga gctttgcttc ccatacatgg ggtcacttga atatgactca
    59281 agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg cagcaagaag ttgcacctat
    59341 cctaggaaaa acaaatattc tgatttatcc atttggtgca gacatcagcg actggcagcc
    59401 ttattcagca gaaaatcaaa aatttgctta cttgaagagt caaggtttcg atattttctg
    59461 taatgtcgat gcttctacac cagcttgggg acaattaggt acggatttct atcgaaatgc
    59521 tcggatcaat atcgatggca ttcgttttca atctgattta gacggaaaaa atcctattct
    59581 tgatccattc atcaatgtcc atgatgtcta tgacaaagaa gcacgcgaat ctgcttgatt
    59641 ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt atcgtcagtt tcggcttttt
    59701 tatgctttat ttcttcttcg gtgcgattcc cttgatcagg acttctgtcc attctgctgt
    59761 atatggaagc agttttgcgt atatctccgg cttagaaatt ccttctacca ttgcttgaaa
    59821 atagaggatc aagaactcat ccgaatattt caaatccact tttccttctt tccgccctcg
    59881 atggaaaaga tcaagcatga tactgaaact ttcttgcgta tacgcatcca tcgcgtcaga
    59941 aaattctttt ttttcttttt ttgtatagta tgtcatcaaa tcgatataaa attgtttgtt
    60001 cactcgattg agataacgga ttttgttttc actcatggca atcagtgttt cttcaaatgg
    60061 aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa tcattcataa atgcaaaaaa
    60121 tacttcataa atcagccctt ccttgctgcc aaaatattta aaaatcgtcg ctttacttac
    60181 ctgagcgttc tcagctacct tatccattgt cactccagcg gttcctatgt ctgtgttcat
    60241 caagtcaaaa gctgcttgta aaatctcttt ctttttctct tgtgctctct tttcaaaacc
    60301 gttcatttgt agagcctccc gtaattttaa acttttataa tatatatagt tcaaatttat
    60361 tctgaggttt attataacta tctattgaga aagtatcaag ctagcaattc cttgtttatg
    60421 aattcattga cagaaattta taaaaagaat attatgtact aaaataataa aaaaagtttt
    60481 ataaaaaggt ataaaacctt tttattaaac tatttaatct tgtttagtat atatttttag
    60541 aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc acacatttga aaaagagctt
    60601 tggtcgtttc gaagctttaa aagatgtctc tttcaccgta cattcaggtg aagtcgttgg
    60661 atttatcgga ccaaatggtt ctggaaaatc cacgacgatt cggacacttt tagggattat
    60721 aaaaaaagac ggcggaacgg caacgatttt tgggcaagat gtatgggaag atagtttatc
    60781 tatccatgaa cgtctttctt atgttccagg cgatatctct ttgtggggaa atttgactgg
    60841 aggagcgatc atcgatctct tcatgaagct tcatggaaaa gggagtgctc aaaaaaaaga
    60901 tgaactgatt caacgtttct ctcttgatcc taagaaaaaa gcaaaaaact attcaaaagg
    60961 aaatcgccaa aaagtgggct tgattgctgc tttggctgtt gattcggatc tctatttatt
    61021 tgatgagcct acttctggtt tagatccttt gatggaaacg attttccaag aagaagttga
    61081 aaaattgaaa gaacagggca aatccatcct actttcttct catattctca gtgaagtcga
    61141 gcgactagcg gataaagtcg tgatcatacg cgaaggaaca ctcgatgaag aaggaacact
    61201 cgatgaattg cgtcatttga ctcgttcgac catcactata gaaacagaag cagagaatag
    61261 tcacttagca caattgaacg gtgtccatga ctttgtgcaa aaaggtcacc tcgctcaatt
    61321 tgctgctgat aacgaagctt tcgatgtgat tttagctgaa gcgtccaaat taggtgtgaa
    61381 aaaatttgaa tctattccac cgactcttga ggatttattc atgagacatt atgaaggatg
    61441 aggaggaagc gaaatgactg ataaattttc acgctggtcc accctttttt ctcaaaacct
    61501 tagccgtgac tggaaaaaga tcctgatatg gctagtcggt gtcactgctt tttctggtgg
    61561 ttttgtccct gcgtttgaag aattgacttc cggacaagga ttagctggat tatacgaaac
    61621 cttgcaaaac ccggcaatga ttgcaatggt cggaccaact ccagcttcga atgctgctga
    61681 gtatacttta ggagcgatgt atgcaaatga aatgttgctt ttttgcagtt tgtttgctgc
    61741 tgtgatctct gttttacacg tggtgagcca aacgagaaaa aaagaagaac ttggtctgat
    61801 tgaacttatt cgttcctttc gagtcggacg tcaagcaaac tctttagctg tcatcgctga
    61861 aagtattctg atcaatttgc ttttagcaat atcgatcagc tgtacgatga tttttttcca
    61921 agcggattcg atcactgcag aaggtgcttg gctttttggg ctatctgtag gtagtatggg
    61981 gattttgggg agtgccgttg cactgtttgc tgcacaactg atgccaagtt cagccagttc
    62041 gaatggtctg tctttagcgt ttttaggtgg actttacctt ctacgagcaa taacagatgt
    62101 agctgattcc tccctttcga tgtggaatcc tttaggctgg tcttatttga cctatccatt
    62161 tacaactaac aactggattc ctttgcttta tttgtttttg ttcagtctaa tcttgataat
    62221 cagttcattt gttttagagg aacatcgaga tttgaacacc ggctatatcc ccgaacgtga
    62281 aggaaaaccg tatgctaaac gttctctttt atccttgcgt ggtttattat tctatctaaa
    62341 taaagggatg acaatcagtt ggcttatcac ttttggtttg atgggggcgg catacggctc
    62401 tatctacggg aatatgcaac agtttttaga aagtaacgac ttaatgaaac agatgtttat
    62461 ccaatctggc gtctcaattg aaaaaaactt tacaagcacg atcatggtag tcttgatttg
    62521 tctagctgct attttaccaa ttgctagcat caatcgttta tttacagaag aaacccacgg
    62581 acgtatgaat cagctgttcg caacaaaaat ttctaggaac caactttatt ggaccaatat
    62641 gttactagct attctatttg ctatattggc aatcctgatt agttctggtg cactagggct
    62701 ttctgctttg gcttcgatga aggatgcgaa agacatggat ctattgatgt ttcttaaagc
    62761 cgggttcaat ttcctgcctg ccgttttagt gtttatcgga attagtggct ttctattcgg
    62821 atggcttcct cgaatcggta aacttgctta tatctactta gcttactcct ttgcactcaa
    62881 ttactttggc ggaattttgg atttaccaga atggttttcc aaaacagctg tccctagctg
    62941 ggttccacgg atgccaaacg attcttttga tctttccgtg ttccttacgt tatcatgtat
    63001 cagccttgca ctgttcgtcc ttggttctat tggttatagg cgaagagact tactagaagg
    63061 ataataaaaa agcatgtaca atttcatgct agcctccaaa tctgggtcaa aaatccaaca
    63121 tttggaggtc atttttttat ttacaagtct tctaactgct ctttatcaat gatccagact
    63181 tctcgattct ttctttttac ataaccattc tcctctaata atttaaattt tctagataaa
    63241 gtttcggggg tcgtaccgat aaatgcagca agttctttca ttttcattgg caggaaaaag
    63301 tgatccttcc ctgtcgcttt agctaagtca agcagataga gagcgactcg ttcttctact
    63361 ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg ttaatttctc aacgttgatt
    63421 gctaaaagtt tcagactaag ggcgggataa tgcagtaaga gttccgagaa atctttttgt
    63481 ctcaatatgc aaatttccgt tttttctagt gcttcgccaa ataaagactc atttggaacg
    63541 cctagcaact ggctctctcc ctcatatccg cccggctcta ttactcgtaa aagctgttcc
    63601 tttccgctag cagataattg atacactttc atactgccgg aggccacgat cactaattga
    63661 ggttctccat tcggcgcaag aatctgttct cctttttcca catagtgatg tttgacaagt
    63721 gcgtgtactt tttcttgatc ttgctgtact aagtgattga acaaaggaac aaatgaaaca
    63781 cataaatgat catgactcat aatctctcct ccttctaaac agctatttct aataaagaaa
    63841 cataacttcc cttattccaa ctgataattt tcttttatca tagcataaac gtcaagcgaa
    63901 ccagatacca gcaaatagag tggatttctt tttgtccctt gctttatttt ccttcttttg
    63961 agaccttaag taattgattc ctatcaattt tttaaatatt tactttttga ataatcaaaa
    64021 acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt atttcgtgtt
    64081 gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc ttgtaaggtt
    64141 tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag tttacccatt
    64201 tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt atcggacaaa
    64261 tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca tatgtaataa
    64321 tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg gttatacgct
    64381 gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata gatttggtat
    64441 tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga ttcgcttcgg
    64501 tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc gattttaggt
    64561 ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat ctctttccat
    64621 ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt tggatggctc
    64681 tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc tgattttcca
    64741 agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt ttgcgatatg
    64801 gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag ccaaacaaaa
    64861 aactgcgatg agcatcaccg cagttttatt gaacttaagg ttgattgatc acatctaaaa
    64921 gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc gatatgtccg attgcacgct
    64981 ctcctagata ggaagctcgt ccttttttag ctaccaagac tttggtgtgt tcttttgcct
    65041 ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc ctctgtgact ggcagccaaa
    65101 catctaacat cgttttatcg tcagcttctg cctttcctcg gctttgaata cccgctgttc
    65161 cctgctcgat cacttcgcct aatttttctt gagaatcaat agaatcgacc tcttttgtcg
    65221 ctttcatcat gttcatgaat gcagatccgt ataacggacc agaagcccca ccgactttcg
    65281 atatcatcgc catagagaat actttgaatg tatcgctgat tgtttcagga tgatcggctt
    65341 gaaaagcttc ttcataagct gaaacccctc ttcccatgtt atttccatgg tctccatcgc
    65401 caatcggggt atctagatca ctgagatatt gtttgttctg attgattgcc tctgcaaatt
    65461 gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat attatcaccc ttttatcttg
    65521 agatttttta ccatgaaatc gtctgtacat tgctttctaa agaatctttc cattgtgtct
    65581 ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc tagtgaggtc ataaaattac
    65641 cgacttttcg gaaaactaca ttgacgcctc tttcttccaa cagagctaaa acatcattca
    65701 tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc gttgactagt acacctgctt
    65761 cttttggtaa attcgagtaa tcatctaaaa tcttagtaac aagttccttt gccagtactt
    65821 tagaaggctg catcttttct cgacgatagc ctggctcacc gtggatacca acaccatact
    65881 cgatctcatc ttctcctagt tcgaatcctg gtttccctac ttctggtaca gttgctgctc
    65941 gaagcgctag accgatcgtc ttagttgcct gtacgacctt ttctcccagt tctttcaact
    66001 cagctaggga agcaccgttt cttgctgcat cgcccacgat tttgtgtaca aggacagtac
    66061 ctgcaactcc gcgttttcca gcagtatacg tactattttc aacggcgata tcatcatcta
    66121 cgatcacact ttctacttca atatcgtcca tagcagctaa ttcctttgcc atatcgaagt
    66181 tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac tccttttcca ctatcggctt
    66241 ccttaatagc cgtctgaatc tgatctggag ttggagaagt aaacacatca ccaagcaccg
    66301 ctgcacttaa catcccttcc cctacaaacc cggcatggga tggttcatgt ccgcttcctc
    66361 caccagaaac caaaccaact tgttccgctt tctgattctt ggctacaaca cgggaagatt
    66421 ctacacgatg aacaagttct ggatagcttt ttactaatcc ttccagcatt tcttcgacaa
    66481 tattgcttgg atcattcatg atttttttca atttattccc atcctttctt tccggcattt
    66541 tgtgcttctg ttaagatttg ctgagtatca tctgttatac cggcagtgat ggctgctgca
    66601 aaagctcctt ccactaaagg cgcatccacc agatgataac gttgctgctg ctcttcttcc
    66661 aacatgtctt ttgccagttc cgagttcaat accgcgctac cgatatccgc aaaaacaaaa
    66721 taactagctg catcgcttga ttcattgact gcttctacga ttttcatcgg gtctgatccg
    66781 atctcgccat ttattccgcc gagagaaaaa atttgcacct cttcggattt ttgcatctgc
    66841 tcaatcattt ctttaatacc atctgttact ttttgactat gagaaataag caaaatactt
    66901 tttttcacaa gaatcttcct ttcttttaca tagttgctaa cgattggttt cgctttcatt
    66961 aatgaacaat tcaagtatat aataaatttc taattttggg aaaatatgtg tagtgcttct
    67021 tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg aatgattaca acaacaacga
    67081 acagtgtaga gggaaaagcc gtagtagctt ataaagggat cgtttttggt gaggtcatta
    67141 ctgggatcca tgcatttaaa gacttggagg cggggttgcg aaatatcttt ggcggccgct
    67201 caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga agcacttgcc gaaatggccg
    67261 aacgtgcaaa agcattagga gctgatgcga tcattggcgt aaaaatggac tatgaagtat
    67321 taggcagcga caatggcatg ctgatggtca catgtagtgg aacagctgtc tccacgagat
    67381 aagtagggga catctgtttt aataactaaa gagagatggg acatgtagtg gcactcaaga
    67441 attagatttt tcagtctaac ttcgaggtac tctaccttcc catcctctct tttttatttc
    67501 tttttgcgga tgattccgta agctgctgcg actaacacac ccgcccctgc taaggaataa
    67561 ctgacagaag ctgttttttc atttgttttt ggcaaagtct gacttgttga tttggatggc
    67621 tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg tcactgattt ttctcctgcc
    67681 gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta agtcagcttt ttttgcttca
    67741 aaatcattag caactgtttg tgcttcgctg atctttccgt ggattgcttg actggccgct
    67801 gtgatatccg cttgagtttg acttagcttt ccagaagctg tttgagcaac ctgatttaat
    67861 tgctgattga attcttttgc ttgttggatc ttcccgtcaa gatctgtttg gacagcttcc
    67921 gcttttgctt tcgcttcggc aagctttttc tcaagttgtg cacggtcatt tcccacttta
    67981 tttttaagat cagctaaatc ttgatcgatt gctgcttggt cttctttcaa tttgtttttt
    68041 gcagcttcta atgcttcttc gagttctttt cttttatttt ccaagtcttg caaatgatcg
    68101 atttggtcag aagaggtaga actatttatt gatgtatctt ctgaagatga aatcgtttct
    68161 cctgaattat ctgtcggtac attggaagtc atttctgttt ccgaggcacc gttttcagca
    68221 ccagaagagc ttatggttgt tgaaggttct gtttgagcag gttcagaagt ttccgcaaaa
    68281 gctgtctgtc ccaataagaa aatactggaa acagcaattg gccagattaa cggcttcatt
    68341 ctttttttca tcacttttcc catccttact actttttaac taatttctta ttataagcaa
    68401 aaatgtttgg aagaaccata aacacaacag gctgtttgtc taaaaaacgg tgcatctttt
    68461 atttttttgt acgttccggg cttttccatg tcccgcttcc ataacctaaa atcgttttga
    68521 ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac tatccagaac aaaagcatat
    68581 atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg atcatctaca atcagcgaag
    68641 ctagcaactg gaaaaatcct gcgaccattt caaagcagat gaacacaaaa ctgaatgtaa
    68701 aagtaatata aatctgttcg tagtttcctt gatatacata atgcccgatt aatccagcaa
    68761 aaagaactac ggaaatacaa aagaatattg accagacaat actcaatgtt tgatcaatga
    68821 agatgatcgt tcttccaata tgtttaaaag gatggagcat cacttttttg aaattcgtca
    68881 gccagacttc tgttccacct tttgcccaac gttttctgtg tcgatatagc atcttcaacg
    68941 tcacaggtac ttccatgaaa aagataatct caggagcaaa aacagataac cagtcattta
    69001 actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg atcttgtctg aatccgccca
    69061 catcgatcaa ggcttctttt cgatacatcg tatttgctcc actgtacgca taaagaccac
    69121 cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat acttgagaat tcaaccgttt
    69181 gagattttgc aatcaatttg gtacgatttt ggacatccat atttgcagtg accgcagcaa
    69241 tatgtcttgc accagggcga atgaaataat tcacatacct aatcagtgca tctggctccg
    69301 gtaccgtgtc tgcatcattg cttaaaatca atttcccttt tgcaaaggca agtccgatat
    69361 taaacgcgtg ggcttttcct ttattttttt cgatccgaac cacacgaaga ttagcgtatt
    69421 ttttcatcag tctagctaat atttctggtg tttggtccgt tgaaccatcg tctgtcacta
    69481 atacctcata gttgtgataa ttcaatttcg tcatcaaata ctcgattgta tattcgatca
    69541 caatttcttc attatgggct ggcaccatga tcgtgatgaa cggttcgaca ctcaagggaa
    69601 catctaccca ttctttttgc ttatgtttgt ataaaaacac ataacaccag acaccaataa
    69661 accatacaaa tccgcctaaa atcggataag aaacgagaaa aaaatacata atagacaaac
    69721 aagtatctaa gaataaatta cctgtatggg tgattgagat catttcagtt ccaccccatt
    69781 ttctttatac aaatctgcaa tgaatgtcgt atctagattt ttctcttcgg agacagaata
    69841 aaaacggacc gtttctctct cttcttttgt tccaaaacgt tccgtataca cttcttcaag
    69901 taattcttgt ctttttttca atttttcatc ttcatattca aaagatttat ttactttttt
    69961 gtatagattt cgattgttcc acctagtcaa tacaaatgag gtaatcagga aactgaaaaa
    70021 aatcaataca aaaaagccga ttaagaaata cagcattttc ttttctgata aaaaagcgta
    70081 caaggaaaaa tccttggctc tttctggtct cgttaatggg aaaaagaccc atataaaagg
    70141 aagaacaacg atcatccatc ctaaaagagc cactaacgtt tgccaaatct ttaaccagta
    70201 attacctttt gaaaaatact tatctttcac caaaattgat gcaacttctt ctcttgttac
    70261 ttttttcata tcctcacctc acgttttttt gttacgacgt aggagtttac catacatttc
    70321 atttcttttc acataaagtg ttcctaaatt tttcctaaga aaaagaacaa aacatttctc
    70381 atcagcaaat gaaaaatatt ttgttctttt tatcagttgt tctttttatt ttttatctct
    70441 taattatgtt gctctttcca atacgacaat gcttttcatt cctctagata tcgccgtgta
    70501 catttgtctg cgtcttcttt gctcatctcc atcgttttca aatggatata agattacatg
    70561 atcaaattcc agtccttttg ctagactcaa aggaatgatt tggcagtttt ctaatccata
    70621 tgaatttttt ttaatcgatt cttgtagcgt ttgggtttcc tcttctgttt gggtgataac
    70681 tgccgctttt tctcctttta gagaaaccaa aatctcagct agtattttca acaattcttc
    70741 agaggatcga aaagagcggt attcgggttc ttttccttgc ggtcggatcg atacgatgtc
    70801 gatcttctct tgatccacag cataggtttt gaaaagctct gtgattgctc cgctagaacg
    70861 gtaactattt ctaagatcat accgatggat cggcagatgg tagtcgtcga aacaacgcat
    70921 aatatcagca aaagtagtgg aagaattaaa gattgcctga ttctcgtcac ctactaaagt
    70981 aaagtgagtt tttggaaata attcgatcaa tagacctaat tgtgccaggg tataatcttg
    71041 tacttcatca atcaatagat agcgaaatgc tggtacattt accttttcaa caagtaaatg
    71101 acgaatagct aatataatga ctgcttcatc aacagtacgt gtgggttgcc aagcataagc
    71161 tgagccatat cgtttttcat aaattctttc aaacaactga tgctcatcca cccatgccat
    71221 ttcttcgatt tgtctggtta tttttcgata ttttttttgt aaaagtttcc ttgcataagc
    71281 tacaatactt tgttccgaat catcagaaat caatttaccg aataattcca actgcctatc
    71341 ttctgtcaac gagagtacct gattctgcac agcaggactt tttgcttgtt tcaaaagatg
    71401 attcttccat tcgctcatca gtgccttttt cgttgcttga agcctatcga tcaatttagg
    71461 atgagcagga actttctcat atattttttc gatcgttttt ttagaaagga ctgtttttcc
    71521 atttttagta agtccacgga taaaattcgg atgatctaaa aacaaaggat ctgattgttt
    71581 tagattatcg ataaactttt tgctacgcaa acgttctgtc tgctccgata cattttctcc
    71641 cgtgatacgt ttgaaataag cctcttcacc ttctatttcc tctgctgaaa gctgtgaaac
    71701 cagctgtatg atggttagat tcagtggatt tctttcacct aatgatggta ggacattcga
    71761 aatatagtcg ataaaccgat gattaggtga tagaatcagc aagtcatcgg atgtcatcgt
    71821 atctcgatat aaatagagca gatacgcaat acgctgcatg atagcagagg ttttaccact
    71881 tcctgctacg ccatttacca agatattttg acttttcaca tcccgaatga ttgtgttttg
    71941 ttccgattgg atcgtagcag tgatagcctt catttcattg gtctcatctt ggcctaagac
    72001 ttctaataat acgtcatctt gaatagctac agacgtatca aaaaacttga ccaaacgatc
    72061 tctttccaaa agaaattgtc gtctttcttt aataaccgta tcgattttat tttgacgaac
    72121 cgtataagaa gatggaccaa tcatgttatt gtaaaaaagt tcggcaattg gtgaacgcca
    72181 atcataaaca agattttcat ctgcatcatc tgtgaaattt gctgtaccga tataaaagga
    72241 ttcttttggc tcattatcca gaaagtctac aacgactttt ccaaagtagg gacttttcaa
    72301 taaacgttcg atctttgcta gctgattttc tgcgtttttc tgtttgatat tcatctgatc
    72361 gatttctcta tttttcattt caatcatcga aaaagtatcc aggttatcta agtaactgtc
    72421 aaaattcaat cgaagctcgc cagccatttc tttcaacgac tggtttcctt ctatttttgc
    72481 cgtatccatc gattcccgca gttcgttttt tttatcaatt agcttttgat acacgttctt
    72541 cagatatgct tcttctaact gtttttgtgt gttgaccata cacattctcc tcttttttta
    72601 aagtggtgga accgattagt ttacctcttt taagagtcga atgcaagctt tttaacgagt
    72661 atcatttgtt aggatatatc agttcttcag gtcggacagt ttgatataaa gaaaatgcac
    72721 catcaaggtt ttttacgtgg tagccagact gcttcaagat tctttccgct agatagctac
    72781 gtaatccgct atgacagctg acgatatatt cttgttggct gtctaattca tttaatcggt
    72841 cccgaagttc attcaaaggg atatgtttgg cttccttgaa tttgcccttt tccaattctt
    72901 ctgctgttcg cacatctaat aaaatttttc cttttgctag ttctgtcggc aattcatgcc
    72961 attgtacggt ttcactaagc ccttctgcaa tgttcattgc tgcatatcct agcatgttta
    73021 ctggatcttt ggctgagcca aatggcggtg catacgtcaa ttctaattcc ggtaaatcga
    73081 agatcgtcaa atgccctttg attgctgttg ctaaaatatc gatccgttta tccacacctt
    73141 ttgccccaac accttgtgca ccataaatct cgccagtctc tggatggaag atcaacttca
    73201 gtaaaatatc tgttgcttct ggataatagc ttgcatgatc ttttcctgat acatgaatga
    73261 cttcaaaaga cagttcgttt tctttggctg ttctttcact taaaccggtg gatgcggcag
    73321 tcattccaaa cgttcgtata attgctgttc caataccgcc ttgatttctt cgagaaattc
    73381 cggaaatcgt gtccgcaact tgtctacctt gacgattggc tggtgaagca agagaaataa
    73441 gtgcatcttt tccagtgatt tgctgtttta caacgatagc atcccccacc gcataaatat
    73501 caggaatatt cgtttgataa cgttcgtcta ctaggatacc cccgcgtatg cctaattcga
    73561 ttccagcggt cactgctagc tggttatcag gacgaacacc aatggataaa ataactaaat
    73621 cagcagggat ggtacgccca tcatccagtc gcaatcgttt cccgtggtct tcaaatccag
    73681 cgacagcatg agaagtaatc acttctactc cttgatgaga caattctttt tctataaaag
    73741 ctgccatttc ttcatccagt gttggaagaa tatgtggtgc ttgttcgatc accatgactt
    73801 ctaaacctct tctttttagg ttttctgcca tttccaatcc gatgaatcct gcaccaacga
    73861 tcacggcacg ctttggctgt ttttctaatg catgcatcac tttatcgata tctggtacat
    73921 ttctaataga aaaaacattg tcggcttctg ttatccctgg aatcgatgga acaactggtt
    73981 ttgcaccagg agataaaacc aatgcatcgt actgttcaat gtgtttttga ccctcatgta
    74041 cgacttctac cgttttgttt tcgggaaaga tggctgtcac ttcatgattt ggacgcacat
    74101 ctaaacaaaa acgagcggat aatgattctg gcgtttggac aagaagattt tcccgttcac
    74161 tgatttctcc cgaaagataa taaggcaagc cgcaatttgc aaaagaaaca tacggtcctt
    74221 tttcaaaaac aacgatttct gcatcttcca ttaatcggcg aagccgtgta gcagcagaca
    74281 ttccacctgc tacacctccg acaataacga ttttcatctt atttccctcc tactgttcga
    74341 tcaaaccatt gattcatgcc accacgtaca ttcactacat cataaccaga tttctttaat
    74401 tctttagctg cttgtttact cctcatccct gattgacaaa tcacatagac ggtcttttct
    74461 ttgtctccat catatctgtt tatactttgt aatggaacat ttttagctcc ttttatatgc
    74521 ccgccccggt attctgcagg tgttctaaca tcaagtaacg ctggattttc caaaagcttt
    74581 tcctttaatt ctgggactgt tatcgatttt attgattgaa atagcaaatt cattttctgc
    74641 acctcattta catttttata aatacctcat ggggtatatt aaacaggagc tttattaata
    74701 tgtcaaccag aatgactctt catttttttc actacttttt atatttgcat aaaataccga
    74761 taaggggtat tatctaatta taaaaataga ggagaatgtg ttatggagat tgataataaa
    74821 aatatcctga accgtttgaa acgtacagag ggacaaattc gtggtatcca aaaaatgatc
    74881 gaagacgaaa aagaatgtat ggatgtcatc actcaattaa gcgctgttcg ttctagtatt
    74941 gatcgcgtaa tgggcatgat cgttgcagat aatctgaaaa attgctttga gaaacctgat
    75001 agtaatccag aagaacaagc ggctaaacta gaacaagcga tcaagatgat tattaaaaag
    75061 taaaggaatg atttcaatga aagtcgtttt ccatattgat gaattagaaa aatggtcaga
    75121 aacagggaaa aacgtaaaaa acctgataaa agcttctcca gaaacgacga ttgtcgtatc
    75181 tgtaaatggc atcgcgatta ccggttatct agactctgcc aatgcagaat tcttagattt
    75241 gcaaggagtc gtttttcacg cttgcgccaa tgctatgcgt gctaatcata tttcagaaag
    75301 ttctttacct gaacaagtaa tcgttgtacc agcaggtgtc cttgatttag ttgaactgca
    75361 atcccaaggt tatgcttata tcaagcctta gtcagtagag gttgcgacag aagtgatcag
    75421 cttcaagaaa tttcggctta tttttcgaag aagctacttc tggaaaaccg tgaatcaaag
    75481 gttgtgaaaa cgctgtcctg catcaagtaa taagaacagc caaacaaaaa tagcttctca
    75541 tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
    75601 agaggttgtg aaatcagcgg tttgacctaa gtattagaga aaaaaacggg aaaatagctc
    75661 ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac accgtttaag
    75721 gaagagattg tgaaaaagtc gcttagtttc gagtattaag aaaaattttg tgaaaatgga
    75781 tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg aataccgttt
    75841 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagaaacaa acggaaaaat
    75901 agctgctcat attttgccgt tttttgagct aataccgaag gtcagctgat tgaacaccgt
    75961 ttaccaagag gttgtgagcc taccatttaa ctccgaatca caagaaataa tttcaaaaac
    76021 aacttctcct gtttttggtt cggttggctt attatcgaga agtagctact gggagtctat
    76081 ttatcaaaaa aaggaatgcg acataggtca cacccctttt ttattttctt tgaaacatct
    76141 ttcggtactc gacagcatac aagacaaaag attgtaaaag accgtaagtg atgacggcaa
    76201 aaatgactct cacccacagc gttggtaatt ctgggaaaag cagcaaaagg atcatgccaa
    76261 catagatgac agcagtcgct actttgccat accacttcgc tccacttaat ttgatatttt
    76321 tagatagccc gattaatcca gctacaaaca taaagccttc ttttatcaag aatagaccaa
    76381 acaacagcca aagccacggt cgataccatg ccatagacaa aatcagaaaa agttgtgtca
    76441 atttatctgc aaacggatca agcaccttcc ctaagtctgt tacctgatta tatctccgag
    76501 caatgacccc gtctagataa tcagacaaac ctgagacaac aatgaccgct cctgctatat
    76561 aaaatgactg tctcagcaca aaataaagat aaatcggcag caaaaaaata cggaatatcg
    76621 ataaaagatt cggaatcgtt tgtatttctt tacgccagtc tgtgcttaat ttcattttat
    76681 cgccctacct cctcagcact cttttctttt tattttagct tacacgggga ataaaaccaa
    76741 tgatttcact gtttttattt ttctttacag acactgatat tatgagctaa tttgagataa
    76801 tcacttgctg ttttcatcgt ttactcttct ttcttcctgt cgtttgcgca tttcttttac
    76861 tagtacttta tgagcttttt ttgatcctcg ctctaggtca cgctgccgtt tacgtgtttt
    76921 ataatcgata aacagactgt ctaaatcgta acctgtcggg tacagatctt ctgctgaacg
    76981 caccagacga acacgctgac gaggcacgtg gattattttt ttgtctaaat atacatcaat
    77041 cgtatcttca cctatatctt cataaactaa cgcttctttt tggtattcat tgacaaatat
    77101 ccgatcacct tttgcaaaga gctgacgttc ttttttattc tccttcctat ttgtaactgc
    77161 tgtcttagga agaaattctt ttttctgtgt ccgataggct ttttccgcca agtaacgctc
    77221 tgcttgatgg atcaatttca tcgacatatc cattttatga gcaatccaca aagcttggct
    77281 ttctcctgtt tcttccaacc cgcaactgat atttaggacg aagtgcttcc cgatcgaaag
    77341 ccatagcagc cggcacaaaa tcttcatgat ctccggcgaa tttcttgatt tctccataat
    77401 gggtcgtggc aatgatcaat gccccttgct catacataga ttccatgatt gcgatcgcta
    77461 gtgcagcccc ttcatttggc tctgttccac tgccaatctc atctaaaagt accaacgtat
    77521 tcctttttat ctttttcaaa atagcagcga tgttttgcat atgaccagaa aatgtactca
    77581 acgcattttc taaattttgg tggtcaccga catcgacgaa aatctcatca aagacagcaa
    77641 gctctgtccc ttcttttgcc ggaacttgca taccgaacat cgccatcaaa gtcaataaac
    77701 cgactgtctt caacacgact gttttgcctc cggcatttgc tccggtgata atcaagcctc
    77761 gatagtcttt accgatttca acatccaatg gtaccgcatg ctcaggtaaa aatggatgtc
    77821 tgccttgctt gataatgata tgttccgatt tattgattct aggtgtgctt ccattgattt
    77881 ctcggctaaa ttttgcccga gcaaagatga tatctaacac cgtgatcgtt tcgatcaata
    77941 aatcgatcac ttcttcgttt tctgcgatag caccagtcaa tgccgccagg acttgatatt
    78001 cttcactgat ttcttcagct tttaacaact gatagtgttc attcaattta gaaatcacag
    78061 ttggttcaat aaaaaccgtc gttcttttat ttgattcatc gataatcgtt ccatctattt
    78121 tatttttata gctggctttg ataggaatcg tatagtattc gcctttttga acaatcattg
    78181 cttcttggat catttctttg tttttcggat gacgcaagaa tttcagtaat tttgactgga
    78241 tttctttttc gattagttgt aattgtttgc gtactttacg caaattacgt gacgcgtcgt
    78301 cactgacttt attatttttt attttctggt caatcaactc ttctacattt atcaaatcag
    78361 gaagatgttt gctataagca aacaacaagg gtgtctggta ttgattctta tcaaaaaact
    78421 ttgtgatcat ccgactgctt ctaagaaaat ccgcatattc gatcaaatcg gttggctgca
    78481 gaatcaaccc ttttttgact tgttctgtca gtgcatcgat cctcggcaac cccataaatg
    78541 gaacatgctg actgctttct aagatcaagc gtgcttctct tgtttcttct tgacgatcca
    78601 agacagtttg taggtttgtc gagaccgtca tatcgctgat tcgttttttg ctatagtttc
    78661 caattgctct tgcttggatt tcctttttga tccgatcaaa ttgtaattga ctaatcattt
    78721 cgttgtccat attctctcct tttcttgaag agatacctgt cccaaaataa ataagggcct
    78781 agagataaat aaaaggatag aacacagctt aaaaaagtca tgtcctatcc ttattagaat
    78841 acaaagatat tgttttcctg acaggtaccg tttcataagc acaccaaata aactttgttt
    78901 attggctatt cgacttactg attagatacc agctacactc acaaaacata ccccattctt
    78961 ctaggtctta tttattttcc acttaactat agcaagacac attttggttg tcaaacttta
    79021 gtatgtttta tagatttaca ccattaatga atagacacct accgcgataa ttgctccgat
    79081 cattggacct gcgattggta cccatgaata tgcccaatct gaagttcctt tattagctat
    79141 tggcaatacc gcatgtgcta atcgaggacc aaagtcccga gcagggttga ttgcatatcc
    79201 tgttggccct cctaatgaaa gaccgatggc taagatcaat ccacctacag cgaatacgtt
    79261 cgttccaggt gcaaattcgt tttgtccaaa agctagcaac ccaagaacta atacaaatgt
    79321 accaattaat tctgtgatca catttgctgg ataattccgt atagcaggac ctgttgcaaa
    79381 cgttcctaaa atcgcgcttt catctttcgt tgcattccaa tgtggcaaat aagaaagcca
    79441 aacaagaatg gcccctgcaa aagctcctaa aacttgcgca atgatgaaag gaacgacaag
    79501 attccaacta attgcccctg tcatcgccat agctagagag actgcaggat tcaaatgagc
    79561 tgggcccatg aatccagaaa tatagacagc cattgttaca gcgagtcccc aaccaaatgc
    79621 gatgacaatc cagccagaag cctgtgcttt acttttgttt aaattcacag ccgcacacac
    79681 accatctcca agcaaaacta ggatcagtgt cccaataaac tcccccatga tttgagtcat
    79741 atcactgttc atttatttct ccccctttag ttcccgcaga tctgattctg caatcaatgc
    79801 ttctaaacgt ttagtctgtt gcgccttctc ctcttctgtc cattcaaaat atccagcaat
    79861 tgcatcgatc acaggttgct tgatctcatc aagctgatct cgttcaaaca acagatgatt
    79921 tgtacgacga atgagataat cgcctggggc caaaaccatt tcttcttcta aaccataacg
    79981 taaccgagct gactcagcga gactcaaacc aggataaggt gccatttctt ttgctaattc
    80041 aaagatacgt cgggcattag tcccgtaaaa atcagcgata taagtagcat cttcttcctc
    80101 taaaccggct gctactcctt cttttgctaa ttctgtcact gtttcttcta atttagttgg
    80161 atcgaagttt ccacctgaaa tctgatattt tttagagtcg atttctttcg tctctattcc
    80221 gtattcttct tttaataatt ggcgtatcaa tcgcaaagct ccttctgcca tcttacggta
    80281 atcggtgatt ttcccaccag ataaagtcag caaaccatct ggttctcttt ctaaagaact
    80341 acctctggaa atcgtagaag gtgctttttc atcacggctg ttttccaaat ggttcaacac
    80401 gtcttctact tcagcacgag aaactttgtt ttccttatat tcacttactg tatcgacaac
    80461 tttattgaag ctcttgtctg aaatcgatcc attatctcca ccattgtaat cagaaccaga
    80521 attaccaatc aacagtggac gaagtcctgc ccagcttgct tcgatatcat tcaatgtgat
    80581 atttgcttct ggatagcgat gattgatcac atccaataga taatctacat cttcttgtgt
    80641 gactttcgga tccgtaaaat ctccttggta atccgtatct gtcgtaccaa agtaagtctt
    80701 gttttctctt ggaatagcaa aaaccatccg cccatcttgc tttcctgtat cgaagtatgt
    80761 gggttgcggt acaggcagtt ttttcgcatc tacaactaaa tggatccctt tagttggacg
    80821 cattttagga gagactggac gcgtaaaatt caagtttcgt actttatcta cccaaggacc
    80881 actcgtattg atcactaatt ttgctttgat ttcgatcact tcatctgtca gcaggtcacg
    80941 agctttgacg ccaacgattt gatcgccatc atataaaaag ccaaccgctt tcattttact
    81001 tactagataa gccccatctt cggcagcctt tttgatatta tcaatcacta aacgggcatc
    81061 attgttgcgg aaatctagat agacacccgc gccttttagc ccttcttttt tcaaaaacgg
    81121 ttctctttcc aatacttctt ctggtgtcag cgtataattc tcatatttgg ttcctgtcac
    81181 atttgccagt ttgtcataaa ggtccattgc tactttgacc gagaacatat tgaaggttgt
    81241 tgctccttcg ccctcataga ttggcaaaag cattggatct ggttttggga tgtgtggggc
    81301 aatactttgt acgactgcac gttcaccaac tgtgtcagct actacttcca catcaaatgt
    81361 cttcagataa cgaataccgc catgaacaag tttggtcgag cgagaggaag tcccttctgc
    81421 aaaatcctgc atttcgatca atcctgtttt gattcctgat gctgctgact ggactgccac
    81481 accggcacca gtgattccgc caccgatgat caacagatcc aattcttctt gctgcatttt
    81541 ttgaatgcta tcttgtcttg tcttgtttga aaacatatgg atttcctcct tattcaaatg
    81601 cttgggtagc ttttactgct tttttccaac cgttgtaaag tttttctcgg cgctcttcct
    81661 ccatttgaac ttcaaatagc ttgccagctt cataaaattc gcggatctcg tctgtatctt
    81721 tccaataacc gacagctaat cctgctaaaa atgctgcccc tagcgccgtt gtttccaagt
    81781 tttctgctcg ttggatcggt acattcaaga tatctgtttg gaattgcatc agatattcat
    81841 tgtttgctgc accgccatct actttcaata caggaatctt gattccagtg tcatcttgca
    81901 tcgtatcgat gatatctctc acttgataag caatcgactg taaagtagct ttaatgatat
    81961 cttcttttgt cgtaccacgt gtcaagccaa acatagcccc tcgtgctgcc tgatcccaat
    82021 aaggagcacc tagcccaacg aatgcaggaa caacataaac ctcatcttcg cttgtagagc
    82081 gtttcgctgc gtcttctgaa tcgctagctt tttgcaacat ttgaagtcca tctctcagcc
    82141 attgaatcga agaaccagcc acaaaaatac ttccttctaa agcatagtaa acctttccat
    82201 ttatgccgta accaattgtc gtcaataaat tatttttgga taattgcggt ttttcaccgg
    82261 tattcatgac aataaatgaa cctgtaccat aagtattctt gaccatgcct ggttcgaatg
    82321 ccatttgtcc gaataatgcg gcttgctggt ctcctgccat ccctgaaatt ggtgcttcgc
    82381 ttccataaaa atgataacct tgcgtataac cataaacttc tgagttagaa gtgacttttg
    82441 gtaacatcac tcgaggaata tttagtaaat ctaaaatctc ctgatcccaa tctagctgat
    82501 ggatattgaa caacatcgtc cgactggcat tcgagtaatc agtaacatgt gcttgtccat
    82561 cggtcagttt ccatactaac caagaatcga tcgttccaaa catcaattcg cctttttcag
    82621 ctcgttcttg cgcgccttct acatgatcaa gaatccagcg tatcttcgtt gctgagaaat
    82681 aggcatcgat cactaaccct gttttttcgt ggaaaaattc ttgatagcct tcatttttta
    82741 agttatctgc aattccagct gactgtctgg attgccaaac aactgcatga tagattggac
    82801 gtcctgtatc tttttcccat attactgttg tttcacgctg gttcgttatg ccaatcccag
    82861 caatctgatt tggtttgatc cctgattcga tgaacgctcc ggcaataact gactgtacag
    82921 aattccagat ttcatttgca tcatgttcca cccaactttc ttgcgggaaa tattgcgtga
    82981 actctttttg agaactgccg atgtgtcttc ctttcttgtc aaagataatt gctcgtgagc
    83041 tagttgtacc ttggtcaatc gccatgatat acgttgattc tgtcattgtg attccctcca
    83101 ttatatgcaa acgctttctt taactactct tatcatacta ctgttttaaa aaaagaaact
    83161 gtcaaaattt tattcttttt ttcttttttt gacagttttt tattatgaag ctatttttta
    83221 atcaattctt ttcttttttc agcgtctcta ttcttctttt caatcgaata atgtcgtaag
    83281 gtgacgcaaa ttctgacaga taatattcac actgtttttt gtttctctgg caaaatgtga
    83341 tcaccaaatc atattcttta ccttcttcat aacttccaat ctcaataccg ccgattcccc
    83401 tcagttctct gatcagatat tgttgaaaag caatacgata aatcggcaga ctttctaaat
    83461 cgattccaat cactactggt tttgcaatat aaaaatcgat catcaaaaga acattggcat
    83521 actggatcat caggtaacta agctcactat cttcagctct tttcctcggc aattgctgca
    83581 ccgctgtttc ctgtaatttc gccagtaact gtgttaagga atgcccgagc attttctgct
    83641 gctgttccaa aagccgatca cgctcataga cttcgatctt tccaacaaag aaaaaccatt
    83701 cattgttgat ctgggaaatt tggtagccta ctgccttttc ttctttgatt ttcaaacgac
    83761 gaggacgata atgccataac atcgtttccc gaatgtaagt atctaaaaca gcggttggta
    83821 actttttgct ccgtgtcaaa tcatactgat aaaatatttc ttcgtctact atcgaaaaag
    83881 aaacaaaaaa gctgtaaaac atcattgttt cgtatacatt cagttctgct gctgttcgac
    83941 taagatgcat cacgatgatt ggatcgattg cttgataaag ccggtccgac tgatagagta
    84001 atttcttttc tttcaaagtt gcgtacgtac ttttttcatt caatagtctt tttttcgtaa
    84061 tcccgagcca gcaagcaatc tgtgcttctg ctgatgccgt aaacgttgtt tctaatacac
    84121 ggtccaatcc tagaatgaac ggtctttttt ctggtgtatt ttgcaaaaaa agcggtcgct
    84181 gatcttccgg gatatattgg aatagttcat aataaaaata tcgtatctgt agctcttctc
    84241 cgtataattg accgtttttg atttgtaatc caaattcctc taagagctgg ttcaattctt
    84301 tgatctttcg aaaaacagaa gactcactga tattaaacgc tgtcgctaat cgaacgatgg
    84361 atacttgctg atgttctaat aaatagacga gcatcttaaa cttcaagctt tcctgcaata
    84421 aaaacaatag aattttttcc aaacttacat cttcgtccaa cacaagcagc gcctgatact
    84481 catttcgctg tacttctact tttttttcca tcattcggcc aatcaattca atatcttcca
    84541 aatattgatc aaacgaggct tttgacagtt ggacatgctc tctcaaacca ttgatagagg
    84601 ctgttccccc ttgcagaaca aggtttcgca aaatcaggat ctgtaactgc tcttttcttt
    84661 ctaataatgc ttcaatcttc ataggcagta ttcgccacct ttgaccacac catatctggc
    84721 acacggtatt ctggctggaa aaatagctca tgttcttcta actgttcaaa cgtccatcct
    84781 tcttctactg caattgtcag ttggtcaaga aggtggaaca tctctttttt gctttggagc
    84841 tgtgctccaa gaatcttttt ttcagaatca aatagaaatt tgagtttaac tttgctttga
    84901 tttattgctg taagcttgta gtctacgtat cctgtttcaa ttttttgggg ataaaaaatg
    84961 ctctcttctt ctgtcaaacc tacgcttcct aagaaatagc caaaccactg attgccgact
    85021 ggacgatagg ttccctgatc ctttgtctgt gagccactaa ttgtcttgct gacatttcgt
    85081 gctgtacgga cagcgttatt tactagagaa acatacattt tttcatttgt tggacgaaaa
    85141 gttacttgga tcgcatcgcc aatcgcataa acgtcttttt gagacgtttg caagtagtca
    85201 tctacccaga tcgttccatc atcattcaat gttaattgtt cttcccacat ctgattgtcg
    85261 ggacgagaat gattagccag caaaacaaga tcatagttct cctttctttt ttccgtctct
    85321 acaatagcgg tttcattttc ggtcaaagac acaacttgtt cttctaaaaa aagtgaaagc
    85381 ccttgatttt tcatttcctt tactaacggt tctgtcattt caggatctag ataacgaaaa
    85441 agaattgact ttcggctttc gtaaagatgg atttgttttt ttcttgatgc caacccttca
    85501 gctatttcga ttcctgcttg tcctgcacca ataattgcaa ttttctttgc attcatgatc
    85561 ttttgctgaa gagccgttac gttttgtatc tttttaactg ggtgaataag cgttgattct
    85621 gcagaaatat ttcgaaactt ttgatttgaa ccagtcgcta gaatcaaacg atcaaaatcc
    85681 aatttttttc ctcctgctaa aacgactttt ttttctttca atcctattac tgtcttttct
    85741 gtgtaaacat ggattcgata gcggtcagtc agttcttctt tcgtgatcca agaaagttgt
    85801 ttttcactgg taacctttcc ttttaatatc aaattgaacc cgctgggaat ccatcctaac
    85861 ttcgattgct tttcaatcaa atatatttca cttgttggca tcaattggcg aagataaata
    85921 gccgcatgaa tccctgcaaa cgacccgccg acaattacaa tgttcatctg cattcctctt
    85981 tcttataagg tgttctactg ctaacttctc aatcagaaaa cacagtattc ataactcgct
    86041 ttcaacctta tgatacatag cgatgcagca gaatcaaccc tctccatcat accgtgttct
    86101 aggtctgctt ctcaataatg tactagtgga cctaattgaa gagtatcatt tctgaagaga
    86161 tgtttcaaaa aatgtactct tataaaagaa aaaaactcgc cttttacgta cctctgtcca
    86221 aataggaaac agaaaagaac gaaaagacga gttttagcgt gtgtaatgta atagttagaa
    86281 tagacacatc atttattttt aattctttaa tgcttcaaca actgcttcgc ctaattgatg
    86341 agcagattga ggattttgcc ctgtaagaag ccgcccatca atttgaacca cttctgaaaa
    86401 agctgctcca gactgatagt ttgctccttt ttctttcaaa gcatcttctg ctaagaatgg
    86461 tacttcattc gttgtaccat ttgcttcctc ttcttcatta ctgaacccag tcactgtacg
    86521 tccagctaaa atagattttc cagactcatc tgtaactggc aacaatccta caacaccgtg
    86581 acaaacagct gagaccagcc cttcatttcg atagatttgt gaagcgactt tcccaagatc
    86641 tattgcttct ggaaaatccc acattgttcc gtggccacca gcataataaa ccgctgcata
    86701 atcatttgca tccacatcat caggacgtaa ggtatttccc aaggcccgat ttctgaaatc
    86761 ttcatcttca taataggccc aatcgatttc atccatattc aaaacacttt gcggttctaa
    86821 aggtacatat ccgcctttag gactgacaaa atctgcatcg atcccatttt ttactaatac
    86881 atcataaaaa tgagtcagtt cacttaacca caaacctgta ggacgctcga tcttttcgta
    86941 cttttctaca tttgttaata cgatcaatac tttcattttc ccatcctctt tctataaaaa
    87001 ttgcgttatt gataacgtgc tttcaagaaa ttatataatg ggcttggcaa ataaagctct
    87061 ttatatgctt tttcaaaagg tttcgttaca aattcatcct cacggttttc caataatttc
    87121 tctgcccagt caggatcgac gatcatttgc tgtccaattg ctgcaagttc tgcatatttc
    87181 aatacctgct ctacatcttc gcgattgcgg atcccaccga caccaactaa agggatcttt
    87241 ccttgaatcg tgttatggac cacttcaaga atcgatttat cgttgtattt atcagaacga
    87301 gctattcgat catacatatt taatgaaaca tgcagataat ctagttttga ctcacgtaat
    87361 cgttcaagaa gccagatcgt gtcttcaaaa cggatacctg gtgtttcata ttcttctggt
    87421 gagaaacgat accctacgat gaatggtttt ttagcatatt gttcaaccgc tgagaaaacc
    87481 gttgttaata attcttcaat aaaacgataa cgattttcca agctaccgcc ccattgatcc
    87541 tctcgtctat tcgaatgcgg agagaaaaat tgttggatca aatacgtatt tgctccatgc
    87601 aactcgattc catcaaatcc tgattcaatc gctctacgtg tggctttgcc aaatgcttgg
    87661 attgtttcaa cgatttcttc ttcactcatt gctcgtggtg tttccgcatc aggacgtttt
    87721 gctgcaactg cacttgcaga tacaggctgt tctccagata aagttgctcg acttgtcatt
    87781 cgtccaccgt ggaaaatctg aataatcgct tttgcgcctt ctccttggat tgctttcgct
    87841 agctcactta atcgaggaat catttcatca tgagcgatgc tgagttcacc tggccagcct
    87901 tttccgatat cttggacatt tgcagcacca gtaataacag caccaagacc tttagaacgt
    87961 tgtttataat aagtgatctc atcttcggtg atcactccat tgaaaaagct gagttgtgtc
    88021 gtcataggcg acagcatcaa tcggttcttc aattgaactc ctgaaggtaa agtaattgat
    88081 tgatcaaatt gtgacattgt cattcctccc ataattcgct ctgattaacc tatcgagaat
    88141 catctatcat taaaccactc gattagttgt acatgcaact aatttgctta aaaaatttta
    88201 ttttttttgt aacttatctg ttgcatcatt cattgtctgg gctaattctt tacttgcttc
    88261 atttcccaaa actgctttgt atgactgatg aagttcttcc cagctaccat cgacttcctt
    88321 agcaaattgg cgtccttgtt ctgtaagata aactaatgac aagcgacctt cgctaactgt
    88381 tttgacgtat cctttatatt ctaatttttc aacaaaacga gcaatcgttg atggggcgga
    88441 atagagcatt tgtgcaatat ctttttgtgg tattccatct ttttctttta atatcaataa
    88501 aataaaacca taagttggtg ccagacctgt ccttctaaac gcttcatcag ctaatttatt
    88561 caacatgcga tctagctttt tcacgctaaa gaaaagacat tcatctaacg ctttttcaat
    88621 tggcttttcc atttcatccc ctccattggc gtacatatca tagtatgatt tttatttttt
    88681 gtcaaaaaac acggaataat gtccgcctcc tctgtctaga tttgaaaaaa agaagtagcc
    88741 atcttcaaag aatttcggct tgttttcgac aaaactcctt ctggaacacc gtgaatcaga
    88801 ggttgtgaaa aagtcgttta gttttgagta tgaagaaaaa ttttgtgaaa atggctttcc
    88861 acatttttgc ataaatttgg cttaataccg aaaaactggc ttttgaacac cgtttatatc
    88921 agaggttgtg aaaaagccgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
    88981 ctcatatttt gtcgtttttt gagctaatgc cgatggtcag ctgattgtac accgtttatt
    89041 gagaggtcgt gagcctgccg ttgaactccg agtcacaagg agcaatttca aaaaacagct
    89101 tctcatgttt tatgactatg gtgacttgtg atcgaggagt tggcaggaga atactgttta
    89161 ttcgtaaaga aggggctgtg acaagacttt tgtcacagtc ccttatttcc ttttattata
    89221 ggatttcgcc atttgattgg atgacttgtc tgtaccaatc aaatgatttt ttctttaacc
    89281 gtttctttgt gccattccct tcgtcatctt gatcaacata gatatatcca taacgttttg
    89341 acatttgtga agtagaagcg ctgacgatat caatgcagcc ccacgacgta taaccaaata
    89401 aatctactcc atctttgata gcttccttca tctgctcaat atgctgcttc aaatagtcaa
    89461 tgcggtaatc gtcttgaacg gttccatctt cttctacttt gtctatagct ccgagtccgt
    89521 tttcagctat gaacagtggt ttttgatacc tatcatataa ttgattcaaa gcaattctca
    89581 aacccttagg atcaatctgc cagccccatt cacttgatgg aagatacgga tttttaattc
    89641 ctccagttat taagtttcct tggacccctt cccaattttc tggatgagca ctgactgcac
    89701 tagacatgta gtagctaaaa gaaacaaaat caacagggta ggctgctaag atttcttcat
    89761 cacctacttc tatttttaag ttgacacctt tttcttcaaa cattcgttgc gtatacgctg
    89821 gataatatcc tcttgcttga acatcactaa agaacaaaga agttctttgc tgctcaattg
    89881 ttttttgaat atcatccgga tcacaagaat acggaacaag aagctgatag ctgatcatac
    89941 aaccgacttg tgaacctttg ataatttcat gacaagcttt tgtagctaaa gcacttgcta
    90001 taaactgatg gtgtgcacct tggtatttcg cttgttccaa atggggatgg ttttcttcaa
    90061 ttactcctac gctaacaaaa gggtgatgtt ttacacagtt gatctcattg aaagtcatcc
    90121 aatattttac tttattttta tagcgtttga atactgtttc agcgaaacga acgtaaaact
    90181 gaataagctt tcgattaggc catccaccat attctgtaac caaatataac ggcatttcat
    90241 aatgggaaag agaaacgact ggctcaatcc catattttag acattcgtca aacacttgat
    90301 cataaaaaaa taatcccgct tcattgggtg tttcttcatc accatgagga aaaattcttg
    90361 tccatgcgat agacatccga tagcatttaa aacccatttc agcaaataaa cggatgtctt
    90421 ctttaaagtg atgatagaaa tcatttccgt gtcttttagg ataataatac ttgctgttgg
    90481 gatcctgcgc cgcttttact tgctgatgcg tcatcatatg ccattgatct gtccattttt
    90541 ctttaggtaa atcgctgtcg aatgtataca catcagacac agataatcct ttttcatcta
    90601 catcccatgc accttcacat tgattggccg ctgtcgctcc gccccataaa aatccttctg
    90661 gaaatttttt catatcgatc cccctaaact tgctagtttt cttgtttgat tatttttctt
    90721 atgactagta atgatatttt tgaatctact actatttgta acaataacca ttgtggtcgg
    90781 atcatatccc tctttgatta attcttgcaa atctacttcc atcaataaat cgcctttacg
    90841 tacttttttt ccatcagata ctgcactttg aaagtatttg ccatttaaat tcactgtatc
    90901 aataccgata tggatcagta tctctgctcc ttcttcactg actaccccaa ttgcatgttt
    90961 cgttggaaaa actgttgaaa cttccccgtt tacagaactg tagatttttc cgtccgttgg
    91021 aatgatcgca aacccttctc ctaaagatcc actagcaaat gttggatcgt ttacttcaga
    91081 taaatcaatt atttcacctg ctgcaggagt acttaacact atatcctttg aggattcttc
    91141 ttcgatttca tccttgtagc cgaaaagaaa agttagcata caggaactga tcatcgctaa
    91201 gaaataacta gcaactagcc aaacaaatcc ttcaccaata taaatcggga aagacaaaat
    91261 acttcttgta gcaactgcca aagcaccggc tcctgcggca ccagctactc caccaaatat
    91321 agctccacat atacaagcaa tgtaaaatgg tcgtttatat ttaagagtca caccataaac
    91381 agcaggttca gtgattccaa ataatgctgt gataaatgca gataaagata aactttttac
    91441 tttcttattt ttcgttttca aaaatacccc aagtactgct cctgcttgcg cagctacggc
    91501 agtcatacat gctggaccta gcgtatcacg accgtagaaa gaaagattgt tggtcattac
    91561 tggtacaagt ccccaatgta acccaaaaat cactaacact tgccaaaatc cgccgataac
    91621 agcaccagat aaaacagggc taaagttata aacagctaaa tatccagctg caatcagctg
    91681 acttgcataa tctgcaattg gacctacaac taataaaata attgggacca tcacgatgat
    91741 acaaatgaat ggtgtcaata aatttcgaat actttcgtgc aagcttttgc gaatcttagg
    91801 ctcaatataa gaaagaaccc atacagctaa aattgctgga ataaccgtac ttgtatacct
    91861 tgctagaatc acgggcatcc ctagaaatcg caaggttatg ctatcactat atgcactgac
    91921 aatcgtagga taaacgagag ctgctgcaat aaccatagcg atgaaacgat ctgtattgaa
    91981 cttttttgca gcagtatatg ccaaaaatat aggcaagaaa tagaaaaatg catcagctgc
    92041 tgcattcaaa atgatataag ttcctgattc agtagttaat aaattcaaac tcgtacataa
    92101 ggcgagtact cctttgatca aaccacttcc tgccaagacg cctaaagtcg gggcaaaaac
    92161 agcggcgatc atgtctataa aagagtttaa aatgcctttt ttctcagttc ctctctttcc
    92221 actagatgca tcatcttcta gtttcatttg tttggataat acgtcataca cttcatttac
    92281 tgcatttcct actacgactt gaaacattcc tccagcttcg actacagtga tcacaccttc
    92341 tagttgctct accttctcct tatctgcctt cttattatct tttagggtaa agcgtaacct
    92401 tgttgcacaa tggtaaacat tgctgacatt ttcttcgcct ccgacaaatc ggacaatatc
    92461 tttcgctaat tgtgaatagt ccatttttac ttcccccttg ttaattaatg ccgtagcaat
    92521 ccttcttaca agataagtat agttcttaga aaacggtttc tccattcaat tagtacccct
    92581 tctaatagcg aacgaaactg tacaatagtg tgtatggttt acttagccga gcaaatcact
    92641 cactgcttga aagaaaacaa gtatatcgtt tctcttatag tcaaaggaga caaaaaaaac
    92701 acgcttgatc ttcctttgct gatgtataag tggtatctca agctgatact ctgtgatttt
    92761 tgtttctact tggcttttga taagacagca caacaaagtc tcggcattta acggaagcat
    92821 aactaggtca gaactaggag agattagttg ctgaatggaa tctatctttt tatggatttt
    92881 tatttgattt tcttctttgt agtaatgatc aagcagtttt gttttctttt tttcttcaac
    92941 tatggtcagc ttttcacgca aaatctgata aatctcccaa gattcaaact catctagaac
    93001 actaggtaga taaatcaaat catcccactc aaaaataagc tcttgctcag tagtcaaaat
    93061 tgcatcatat tccgttattt tgtttgattg atttttgaaa agatacactg gttctatccg
    93121 gcattctttg atccacatgt tcatactttg ttgaatctgt ttttttagtg tattcaaaat
    93181 actaattggc tggttactaa caatcagtat ctccccttgt tttcgaaaag gattcaacgc
    93241 ttcggcaaga tacaaaacaa aataagcgct ttcagctaaa ttgggacgta attgaaaatg
    93301 tattgggaag aaacgccgaa ttaaataaat ttctaaagga taacgggaga tgatcttttg
    93361 tacaaaatga ttcatggtat tatgtccggc atccatcctc gttttcattt gtttgatatg
    93421 ggttagcaaa aattctgttt catggaacaa taacgaaaca ggaagatcta aaaaacgaat
    93481 aatcgtttgc tcaaatgctc ttagattctt ctctatttct ttgttttttt catcattaat
    93541 catcaaataa tttaactcta atagtcgatt ttcaattgct tgtttttctt gattggaaaa
    93601 agaatagggt agttctgatg ataacttttt tgtgagggtc tctaccatcg gaataaataa
    93661 tgtatacctg tttgtttttt ctaaaagttc ttctcttcga agaatggtca aaacgagata
    93721 ccgagaaaat cgtatgaagt cctctcctga aacaatataa ttatatgata taagaacctc
    93781 ttttaatgtc ttttggacag tcggcatgat attggaaaaa attgtactga tttgttgagg
    93841 aaaccttgcg tgttggatca ccgtttctgt tccaacaaga gataagaaaa ttctttttga
    93901 attttcttca gcaatgattt ttagtccttt tgtcgacgaa acttccagtt ctaatttagg
    93961 attgcgctcg atccaacgca aaatcgtttt tatttgtaat gatacggctg tttttgaaag
    94021 aaagaaaatg tctgctatct tttgcatact gacataccct ttttgaaaca ataagtacgt
    94081 cacaatagtt gaagctcgga aatccatgct ggaatagatt ttatgtttcg tcacctcttg
    94141 tatgatttgc tgtttagttt cagattcaat tgattctaaa aaataacctg aacgtttatt
    94201 tgactggata atgattttct tctcgtagat agcaagcata tttttgattt cagtttggat
    94261 cgttttcttg ttggtaccta aagcttcagc taattcttcg cttgttatcc aatgattctt
    94321 atttcttaat actacaagaa tttggagttg tcgtttattt aagtccattt gcttacacct
    94381 cctctttgtt ataaacatac aggaaaaacc tctcaaatga caatagtcac ttgcagaggt
    94441 ttaaaaatca tttgaagaaa gatctatatt caaggttttt accattagac tggataattt
    94501 gtttataata ttcaaaacta tcttttttca atctcctaaa gcttccgctc ccatcatttt
    94561 gtctatccac ataaataaag ccatatcgct tcctcatttc ccctgttcct gccgatacga
    94621 tatcgattgg tccccaccat aagtaaccaa tgatttggca accatctttt attgcctcag
    94681 caatttcctg aagatgtatt tttagatact cacaacgttt tggatcgtgg attcgattca
    94741 attcatctgg tgcttcatct agtccaatgc cattttcaac tatgaataat ggtaattcat
    94801 aacggtctgt caattcattc atgacataac gaaaccctag aggatcaatt ggccaactcc
    94861 aaggttcggg agatttttcc ttcaaaaagg gattatcgaa accatttgct ccgccagtat
    94921 ctacgcgcat ttctgcttct tttttataga cagcgctacg ataataacta aatgcaatat
    94981 aatctgccgt gttagcttgc aagcactgtt cgtctccatc taacattact ggtgcacagt
    95041 cttcttcctt ccatgtcctg taaatataag ctggataatg ccctcggcac atgacatcgg
    95101 agaaaaacca tgaattgcgt ttaaattgca gtgaaccaaa tacattctct ggatcacagt
    95161 catatgcata agtcgctaat gcagaaaagc tacacataat acccatctta gcatttggat
    95221 cgattttctt taataattga gtagcacggg cgttcgctag aaacatatga tgacaggctt
    95281 gataaatcac tttttttgtt agtgtagcaa tgggttcaag tttatctcta gcagggaatg
    95341 taaccaatcc agcagctgca taaggcatac gaaaagcatt attgatctca ttaaaggtca
    95401 tccaatattt cactttccct tggtagcgtt caaagacggt ctgcgcataa aattcaaaaa
    95461 agtcgattaa ttttcgattt tgccaccccc catactctcc taccaatgct aagggggttt
    95521 cataatgact aagagtaatt actggctcga tatcatatcg atttaatgta ttgattagtc
    95581 tgtcataaaa tacgagacca gcctcatttg gcttctgttc gtctcctctt ggaaatattc
    95641 gtgcccatga gatgcttgtt cgaaaagctt ttaaacctaa ctccttcagt aaacgaatat
    95701 cctcttcaaa tcgatgataa aaatcaatcg cttcatgaga aagataatgg agtgattcgt
    95761 ctaaagcaat ctcccaaatc tttttttctt cattccactg aatactagga tgctggttca
    95821 tgatcccgat aagcgtatct gtcacattag gtaatttgcc gtcttccaac catgcacctt
    95881 cacattgatt agcagctact gctccgcccc ataaaaaatt ttctggaaat atttcctgat
    95941 ccataactat ctctcctcgc tatcaacaat ttcttacttg aagtatagct cgattcatca
    96001 aaacaagata ttctaactat ttcggcagaa gagaagaaaa aaattgaatg ctactcttca
    96061 tttttaatat ttatatataa caaatacata agacgatccc cgaaagaaaa cactcgttaa
    96121 ccatctaagc aaacgattta ttttacttcc aacacaaatg cttcataagg tcgtaaatca
    96181 actttgccgt ctggtaactg tttcagagga taatttgaca caataaccct taaagcttca
    96241 cgtggaatag tgaacgtctg cttttcactg gacatattac aaataacgag ccattgctgg
    96301 tcttcatata tgcgagaata ggcaaagaca tgctcaggcg tcttttccac taattcatag
    96361 tctccccaga cgatgatgtc atgttttcta cgcaaatcga tcaatttctt gtacatataa
    96421 aaaacagaat cttgatctgc taacgcttct tctgcattga tttctttata atttggattg
    96481 actcgaagcc atggaattcc agtagtaaac ccagcatgtt cacgggcgtt ccattgcata
    96541 ggcgtcctag cattgtctct tcctttcgcc ttgattgatt ccaagatttc ctcttttgta
    96601 aatccagaag aaatcctttc gttatacata ttgattgtct caatatcttt tgcttccgcg
    96661 atatcatcga ttgggcaatt cgtcatgcct aactcttctc cttgatagat ataaggggtg
    96721 cctttcatca tatggagcaa gatagcaaac atcttggcac tttcttttcg atacacatcg
    96781 tcatttcccc aacgagaaac aattcgcgga agatcgtgat tattccaaaa taaactattc
    96841 catccttcat cacctaaaga tgtttgccat ttggataata cttttttcag ttcagagata
    96901 ctcaagggtt tcaaatccca tttgtctttg ccttcttgct gatctaatcc tatgtgttcg
    96961 aattggaaga ccatggataa ttcatttctt ttaggattgg aataaagttt agcgatttcg
    97021 gtagttgctc cccatgtttc gccaacagtc atcagatttt tgtcaccaaa agttgcttga
    97081 ttcatttcct gaagatactc atgcagttta ggtccattac ttgtgatttc tttatccggt
    97141 tctttgccaa tcatatcgat cacgtccata cgaaagcccc caataccttt atcgatccag
    97201 aaattcatca tttgataaat ctcttggcga acctgtttat ttttccaatt caaatcaggt
    97261 tgacgcttgc tatacaagtg cagaaaatat tgccccgttt tttcatccaa ctgccaagca
    97321 gaaccactga atattgagcg caatctatta ggctcttttc cattgaccgg atcacgccaa
    97381 atataatagt cccgataagg attttcttta tttttacggg cctcaatgaa ccacggatgt
    97441 tcatcagaag tatgattcac caccagatcc atgatgatac ggatatttct tttctttgct
    97501 tcttcaatca gttcttccat ttcttccatc gtaccgaatt ctgccatgat tgcttgataa
    97561 ttactgatat catacccatt gtcatcattc ggagactcgt atactggaga aagccaaatt
    97621 gcatcaatac ctaaatacgc cagataatcc aacctggaaa taatcccccg caaatctcca
    97681 ataccatctt gatttgaatc ttgaaaactt cttggataga tttgataaac aactgaatgg
    97741 tgccaccatt tttgttccat gattttcctc ctataaatgg atgtttctat tttttgctta
    97801 atcatttatt ttagtctctc tcactaaaaa ttgtaacgct ttcaaatagc tattgcacct
    97861 tgttatcggt aacagaataa aacaaaaaaa cagctgagga aattccctca actgtttttt
    97921 gaaaggattg atttatgcag ggaagaatgc tgatttcaca acttctttat aaacggtgtt
    97981 cactcagctg tcccttggta ttagctcaaa aaacggcaaa atataagaaa ctattttttc
    98041 gtttttttct ctaatactca ggccagaacg ctgatttcac aacctcttta tttcacattc
    98101 aatatccaca tgaatcccac aaatacaaag aacagaccat acatgattgg agatacttct
    98161 tttcctcttt tagctgctaa catggtaatt ggatagaaga taaaacctaa tgcaatccca
    98221 tctgaaatac tataagtcaa aggcatgccg atcaagatca agaatgaagg gatcgcaatc
    98281 tctaagtttc cccattcgat ttgtcgcaaa gattgtgcca tcaatactcc taccataatc
    98341 aatgctggtg cagttacttg tgaagtaaca actgatagta atggagaaaa gaacaagcct
    98401 aacaagaaga aaatccctgt agtaatagct gtgatacctg aacgtcctcc aacggcgata
    98461 ccagctgatg attctacaaa tgcaccaaca ggagaagtac caaataagga acccgcaagc
    98521 atagctgttg aatcagaagc taaagctttc cctacacgag gcatcttgtt gtctttcatg
    98581 aaacctgctt ggtttgctaa tccaactaaa gttcctgctg tatcaaagaa agtcacaagc
    98641 aagaatgtca gcactacgac ccacatttga agagaattga tgtcccctac atgttttaat
    98701 gcaactaaaa atgttggttt caaacttggt gctgcggcaa caatttcaga aggcattgga
    98761 atcaaacctg tgaccagacc taaaatcgtt gtagctgcca tcccgatgaa gatgccacct
    98821 ggtacacgcc gaacaagcaa gatagcagtt acgactaatc caaaaatcgt caaccaagta
    98881 gaaccaacgt tgagtgatcc taatcctact aatgtagatt cattcgaaac gatgatccca
    98941 ccttcgctca gaccaaggaa agcgataaat agaccgatac cgccagaaat cgcatatttc
    99001 aaatctgctg ggatcgcatc aatgatcatt tcccgcagct tgaagattgt gatcaaaata
    99061 aaaatcaaag aagcaacgaa tacgccggct aatgctgttt cccatggaat ccccattcct
    99121 aaacaaacag aataagcaaa aaaagcattg atcccaagag caggtgccgt tccaattgga
    99181 taacgggcta atacccccat taaaacacag ccgatcgcac tggctaatgc agtcgcagta
    99241 aacactgctc cttcatccat tccagaagca cctaatacag ttggatttac aaataagata
    99301 taagccattg agataaatgt tgtaaatcct gccagtacct cacgttttac cgtggtgttc
    99361 aatttttcta tttcgaagta ggaaagtatt ttttccttca tcttccatcc ccctaaatcc
    99421 gaacattata aataaagtcc gttaaaattt cgatttatta ataaaacaac gtgttttatc
    99481 atatactaaa acaaaacata agtaaacaaa aaattcggat tttaagcaaa atccgaacgt
    99541 tccatctgat taaatccctt tatctcaaag ttcatgaaca ttcactttgg attacaagaa
    99601 tttctttatt gtgttaataa agtttcttca ttctagtctc aaaaatcaat agtgtgattt
    99661 gattttacca tttcgtttct gttcttcttt gatgaattct tttgtatcga caggattcag
    99721 attatttagt ccgccaaaac ctgtatcgac catttttccc cagccttttg tcttcttttt
    99781 tcctgatttg agattctttg ctcgaagctt ctcactatgt tttgctcgcc gatacttcaa
    99841 ataaccttct aatcttccca ttagatccac tgtttttcct cctttttatt caatcagacg
    99901 actcagcttt tcctataaca aaataattgc cttcagggtc agaaaaattg aaagtcaaga
    99961 tgccattgtt atctgtgatt tctcctggtt cttccatgtt ctcgtagata gtttcaaatt
   100021 catccgtaaa aaatactaaa gaaggcggtg gtcctaatac ctctggtgaa aacttctgca
   100081 caaatacttt tgggaatacg cctaattcta attcttttga gatgctgagt acaatactct
   100141 taaattcttc tggcaattcg attgtttcag aaatttctgc accaattttt tctacaaaga
   100201 atcggcaaat catctctacg tcattgacat aaagcatcac acgtgttttt tgtatcatca
   100261 tttgaccctt ctttctattt gattttcttt cctgtctata aactgattcc attatatcac
   100321 gaaagcgcaa acaccttgtg tttgatacta ttcaagaaaa ataaagcaat agtttctagg
   100381 attgctttcc tccacaaact ttttttacaa aaaaaaaacg gcaatgaatg ccgctcttct
   100441 tatttcgatt cttttataat tctgcttctg attcatcttt ggttagtgtg tgtctaacac
   100501 tagttacgcc aaatgtttga tcgatttttt ccttcaacgc ttcgattgcc tgtgcgccac
   100561 gtgccgcttg ttcagcattg atggattcaa tgaccagcac cgctgcttgt gtttcttccg
   100621 tcagcatcgt tctttgggct tcacgccagt tgagacagcg acagatcgct ccttgttcat
   100681 catagtagat gatttcttcc ggaagtgccg gagcatcgga atctgcacct aaaggcagga
   100741 atgattcgcc accttgggct tttcctaaat gcagatttcc tgcgatcttt tcgatatctt
   100801 ctccgccgca aggtacgcca aaagacaagg aaatactatt atagatatct acaagcggat
   100861 tgattgggaa aaattcccgt tcttgatttg cacgtttcag taaagcttca atagaagaac
   100921 gtgcaccttt tttagtcttg aatgtggtaa atgcctgacg ccactgagca atgacttcgt
   100981 tttggctgaa tgtttcttct gtaaggtaat ttcttgcttc ttttgctgcc tcattcaata
   101041 attgatgata cgtttcttca ctttcttttg ttacgtggtt atcgatacca tttacggata
   101101 agatttcgat ggttgcttca ggaaatactt cccagaaatt ggtatccact attacttttt
   101161 tcatctgttc acacctcttg attagaataa ttgcttgatg aatagatagt ctgtttgggg
   101221 atcatctccc atataaaaaa catgttcgct gtatttgata aatccttttt tacgataaaa
   101281 agcgagcgca acatcgttgt gttcccaaac accgagccaa atggctgttt tttgcttttc
   101341 ttttgctttt tcaatagctg tatctagtaa aaatgtaccg ataccttgat gtttaaattt
   101401 ttttcgtaca tagattcgct cgatttctaa aaaatgatca gccatttcct cagattgact
   101461 cgttcctgta tttagtttca ggtaacccgc aggctcttga tcgatactca ctaggaaaaa
   101521 atcggtttct ttatctttta gctcttctgt aagtttttct agtgcataag cttgtgtcaa
   101581 gtaatcagct aaatgctccg gtgaattatc ttttccaaat gtatctgtaa atgtttcgat
   101641 actaatttgt tgtagtaagt ctacatctga aggcgtcatt tttcgaattt cgtatttatt
   101701 cacggcttct tcctttcaat agatcctttt attgcctttt ttgacaaaat tccaatcttc
   101761 gctaacattc ttgcatactt tatttaaaag atattccaat tgttttgctt cttcgtcaga
   101821 aagaccattt aatgcgactg cattggagta gttgttttct cgaatgatga aaggatagat
   101881 ttctgctcct tttttagtcg gatagagttt cttgattttt ttattttctt tatcttccaa
   101941 acgttcgatc atcccattgg attctaattt cttgattgct cgggcagtcg ttgtacgatc
   102001 tactttgatc atttctgcta gtttttcttg gatgattcca ggattttcgc aaatacgtac
   102061 taaataaaga tactgtcctc ttgttaaatc gacttctttg aattcgatat tgctaataga
   102121 atctagcgct cgggcaatca ttccgatgtc tcgaaggatt tcagccattt catcccacct
   102181 ttattttgtt tgtaagacta gttcacctct ttttgttgca aatgcaacta ttttcaataa
   102241 aaaaatcaag ttctttttta ataactagta aagtatattc ttttcttctt ttacgaaaaa
   102301 gctcaatcac aatagatctg gtttttgttt tctaaaataa gtaactgttt cttcgttgtt
   102361 cgcttttctg atagctttgg caactcttct atactaaaaa atcccatgtt ggaagtttca
   102421 ttattctcaa taaacttggc ctcttcaccg tggatcgcac aagcaaaaac aagtttataa
   102481 tactgaaaaa gctgtggaat atctttttgt ttattcgtat caaaaactgc tcgcaactga
   102541 gtagtttcta ctgttaatcc tgtttcttca tagacttctt tacgcacatt ttcttcagga
   102601 gacaatccta tttcagcaaa tccaccagga agtgaccatt ctttcgtccg tttatcttcg
   102661 attagtagga ccttgccatc ttttttgata taggcacgaa catctacttt tggtgttgga
   102721 tgtccttctc caatcgttgt gagcgctttt atttcttcga aagtttcttt tcctatttca
   102781 ctgatcagtt ccaatgaaat cgtccggatc tcctcaaaac gctctttatc aaatacatct
   102841 tttccataat atagaccagc ttgagaaagt gcgagtagtc ttttgtattg agccaacttc
   102901 ttgttcattc tcttcccttc ttttttagca aatgtatgac tatgtaatca agtatagaag
   102961 actggtttaa ttacggcaaa taaatataat gaaatctgca ataaataaaa gaatgttaaa
   103021 aaactcgaga acaaaagaca ttcgacttct ctggggctgt gaataaatgg cgttcaaaag
   103081 cttgcatctg cggtaataag ccccaccaaa cgaaaaatat gacgagctat tcttgtctgg
   103141 ctgttcttat taattgaggc aggacagctt tttcacaacc tccccactaa acggtgttct
   103201 cctaccaact cctcggtcac aagtcacaat attcatcaaa catgagaagc tgtttttttg
   103261 aaattgctcc ttgtgactcg gagctgaacg acaggctcac gacctctcgg taaacagcgt
   103321 tcaaaagcca atttttcgat attaagccat ttctttgtta cttattgtca ttgatttctt
   103381 tttctaattt atccaatagt ggagtgtaat ccacttgagt atagtctgtt acatcaaatt
   103441 catatagtgt tcctaactgg aatttgtcat attttcggtc ggcgatgatc tttttgaatg
   103501 cttctttcgt aatatgattg gtccctttcg ttcgatcttc caatacgtca ccatagtgat
   103561 aatgatccat gatatagctc aaatgacgat ctgattcacg atcacgtttg taccgacgtt
   103621 gccataacac ttcaaagtct gctgttaggc gaatcgtgat cacctgatat ccgtatctat
   103681 ctgctaattc ttggagtcgt gctttttgct tatcactaaa aggatactcg gacacaatca
   103741 ctttctttcc tgcttccata tacaaatcaa gtgctttgta atagaaagga taaactttcg
   103801 tcctttcttg ttccgcccgt tcttccaaat tgttaaaccc gatggattct gcatagtatt
   103861 ccttgatttc atcgagcgtg atggcataca tatctggaaa tcgttcccgt agtttattca
   103921 taagatatgt ttttcctgta ccaggactac cagccagaag aatgaaatac tttttcatct
   103981 catttatttc ctaagttaat tggactttcc aagttcataa acagtccaat cttatgcttg
   104041 acaatttctt ttactgcttc atttgctgga atcacattat ggcgaagaga cttgttgatt
   104101 tctgtttcac taaaggtttc tttagctact ttcgtccagt tgactaaaag ctccgttcca
   104161 acattgaatt tgcggatccc gttattgatc aattcaggat aatcttcttc tttcacacct
   104221 gttcctccat ggataactag ggggacatca actactgcat cgatttcttt cagcaaggga
   104281 atgtttactt ctgtttttga tttgaattgt ccatgattcg taccgatagc aatagctaat
   104341 gcatccacgc ctgtagcttc tacaaatttc actgcgtctt ccggtcttgt atataccttg
   104401 tcattttcag cgacatggat tccttcttct gtaccgccga ttgttccaag ttctccttct
   104461 acggaaacac cgtgcgcatg ggcatattct actactgctt ttgtcttcag gatattttct
   104521 ttgaaaggca gatgggaccc atcatacatg acagaagtat atccgctgtc gattgcttct
   104581 ttgatatcat caaagtctcg ggcgtggtct aagtgcaaga ctgcatcaac catttcttct
   104641 tctgcaatag ctgtcattac attgactaac acatgcatgc cgatatattt agcggtatcg
   104701 acacttgttt gaataatgat cggcgaaccc atttcttttg ctgcgcctag catagcagga
   104761 agcatttcta ggttatgcgt attaaaagct ccaactgtaa aattcaactc ttctgctgtt
   104821 tttgttactt ctttcaatgt tgtatacatc ttttattgcc accttatctt tttatttgtt
   104881 tcctttgatc gttacttgtt ttgcaatttg tcgcatctca tccattttgc ccatgtagta
   104941 atcgatccct tgatcatcac cagcacgagc agcatctgca cgcttctggt tatagaggct
   105001 catcagtttt ttatacccat ctccgatcgt ctgtttattt tccaaactct tttctaaata
   105061 ttggatggct tgatcgttca catacaattc agaaaattta agtccaactt gttcataaag
   105121 tttcgctaat ttatgcttat cttgggtagt ggaaatctct tgtttcaatt gtgtaatctc
   105181 tgattgaatc ttttcggtcg cttctggcga tagggctttt tcttcttttg ccagaacttt
   105241 tttcggttct ttttcttttt tcttaaaaaa tccaaacatc attttcccta ctttcaatta
   105301 aaatgctttc aaaactgggc ttaagatcca ggcatataag agtgctgcgg ctactgtatc
   105361 tacatcggtt gctgtagcat tgttgaatcc catcgaatta aagatcgtta ctagcaaagc
   105421 gggcaataat gtaataaaga aaccatgagc aataccgcca atgatcgctc ctcggcgtcc
   105481 gccaactgcg ttgccaaata tccctgctgt ccctccggca aagaaattgg ttagcatacc
   105541 aggtaaaatc atcgctaagc cgaacatggg caaagtaaac atggcaataa tcgtaccaat
   105601 cgttgtcgta atgaaaccta aaatgacagc atttgggcta taaggaaaga aaactggaca
   105661 atctaaggca gggatcgcat caggaactaa tttcatagct atccctcgaa atgccggcac
   105721 gatttcacct aacagtagac gtacaccagc tagcaataca tacacaccca ctacgaattg
   105781 gatggcttgt aaaaaggcaa acatgatata gttttgatct cctgataatt cagaagcgaa
   105841 tggttcgcct gcaaataaaa cagtgatgat atatagcggg accatcacga ccatgacaga
   105901 caaataagta tcttgcagaa attcgaaatg tgtcggcaac ttgatatctt cgatcgactt
   105961 tttattttcg cctttctcac caaaaagctt agcaacaccg gcttcaaata agtacccgat
   106021 cgtacaaaaa tgacctaaag caatatcatt tgatccagtg attttacgaa tgatcggttg
   106081 cgctactgcc ggcatagcaa tggcgaaaca agctccgata aaaccaccga ccaagatcaa
   106141 tacgatccct cgcagaccgg caaaatagcc aaagactgtc gtcatcgttg ccatccataa
   106201 aattgcttga ccagttaaaa aaatgtactt ccattttgtg aaacgagcca aaataatatt
   106261 gaatacaaaa atggctaaga acgtcagtgc aatatctcta cctaaaccca aatcattcat
   106321 tgcttgacca ttgatagatt caatagaagg gatgatccct tgcatatgaa atccttcagt
   106381 aaagattttc ccgaaataag ttaaacttcc aacgatgatg ctcgaaccgg cactcaacac
   106441 ttgaaatcct aggagtgtct ttaacgtgcc agagatgact tgtcctgctg atttcttctg
   106501 cagtagtaga cccaacatag caatcaatgc aatggtgatc gatgcctgag tcaaaatatt
   106561 ttcgatgata aaattgataa cgcccatgtt
//
LOCUS       DAFLWZ010000002        97346 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000002 DAFLWZ010000000
VERSION     DAFLWZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 97346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.002"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            37..1161
                     /locus_tag="L1V38_000093"
     CDS             37..1161
                     /locus_tag="L1V38_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1314678.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1388..2305
                     /locus_tag="L1V38_000094"
     CDS             1388..2305
                     /locus_tag="L1V38_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1314679.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2298..3131
                     /locus_tag="L1V38_000095"
     CDS             2298..3131
                     /locus_tag="L1V38_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1314680.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3214..4332
                     /locus_tag="L1V38_000096"
     CDS             3214..4332
                     /locus_tag="L1V38_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1314681.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4326..6224
                     /locus_tag="L1V38_000097"
     CDS             4326..6224
                     /locus_tag="L1V38_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBN1314682.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6218..7441
                     /locus_tag="L1V38_000098"
     CDS             6218..7441
                     /locus_tag="L1V38_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1314683.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7527..9461)
                     /locus_tag="L1V38_000099"
     CDS             complement(7527..9461)
                     /locus_tag="L1V38_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1314684.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9687..10343
                     /locus_tag="L1V38_000100"
     CDS             9687..10343
                     /locus_tag="L1V38_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1314685.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10417..10770)
                     /locus_tag="L1V38_000101"
     CDS             complement(10417..10770)
                     /locus_tag="L1V38_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1314686.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            10962..11891
                     /locus_tag="L1V38_000102"
     CDS             10962..11891
                     /locus_tag="L1V38_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBN1314687.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11902..12738
                     /locus_tag="L1V38_000103"
     CDS             11902..12738
                     /locus_tag="L1V38_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBN1314688.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            12986..13762
                     /locus_tag="L1V38_000104"
     CDS             12986..13762
                     /locus_tag="L1V38_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1314689.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            13938..14681
                     /locus_tag="L1V38_000105"
     CDS             13938..14681
                     /locus_tag="L1V38_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314690.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14674..16254
                     /locus_tag="L1V38_000106"
     CDS             14674..16254
                     /locus_tag="L1V38_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBN1314691.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16505..16984)
                     /locus_tag="L1V38_000107"
     CDS             complement(16505..16984)
                     /locus_tag="L1V38_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1314692.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17000..17752)
                     /locus_tag="L1V38_000108"
     CDS             complement(17000..17752)
                     /locus_tag="L1V38_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1314693.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17869..17939
                     /locus_tag="L1V38_000109"
     tRNA            17869..17939
                     /locus_tag="L1V38_000109"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17901..17903,aa:Gly,seq:ccc)
     gene            18300..19025
                     /locus_tag="L1V38_000110"
     CDS             18300..19025
                     /locus_tag="L1V38_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1314694.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19280..19546
                     /locus_tag="L1V38_000111"
     CDS             19280..19546
                     /locus_tag="L1V38_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBN1314695.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19543..19974
                     /gene="ruvX"
                     /locus_tag="L1V38_000112"
     CDS             19543..19974
                     /gene="ruvX"
                     /locus_tag="L1V38_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBN1314696.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            19999..20304
                     /locus_tag="L1V38_000113"
     CDS             19999..20304
                     /locus_tag="L1V38_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBN1314697.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20385..21530)
                     /locus_tag="L1V38_000114"
     CDS             complement(20385..21530)
                     /locus_tag="L1V38_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1314698.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21591..22238)
                     /locus_tag="L1V38_000115"
     CDS             complement(21591..22238)
                     /locus_tag="L1V38_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1314699.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22432..22725
                     /locus_tag="L1V38_000116"
     CDS             22432..22725
                     /locus_tag="L1V38_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314700.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22769..23080
                     /locus_tag="L1V38_000117"
     CDS             22769..23080
                     /locus_tag="L1V38_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314701.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23077..23701
                     /locus_tag="L1V38_000118"
                     /pseudo
     CDS             23077..23701
                     /locus_tag="L1V38_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23842..24000
                     /locus_tag="L1V38_000119"
     CDS             23842..24000
                     /locus_tag="L1V38_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314702.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24001..24363
                     /locus_tag="L1V38_000120"
     CDS             24001..24363
                     /locus_tag="L1V38_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314703.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24400..25248
                     /locus_tag="L1V38_000121"
     CDS             24400..25248
                     /locus_tag="L1V38_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBN1314704.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25238..26713
                     /locus_tag="L1V38_000122"
     CDS             25238..26713
                     /locus_tag="L1V38_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBN1314705.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            26979..27386
                     /locus_tag="L1V38_000123"
     CDS             26979..27386
                     /locus_tag="L1V38_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBN1314706.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27389..27604
                     /locus_tag="L1V38_000124"
     CDS             27389..27604
                     /locus_tag="L1V38_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314707.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27608..27988
                     /locus_tag="L1V38_000125"
     CDS             27608..27988
                     /locus_tag="L1V38_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1314708.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28122..28277
                     /locus_tag="L1V38_000126"
     CDS             28122..28277
                     /locus_tag="L1V38_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBN1314709.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28346..28819
                     /locus_tag="L1V38_000127"
     CDS             28346..28819
                     /locus_tag="L1V38_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1314710.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28816..30510
                     /locus_tag="L1V38_000128"
     CDS             28816..30510
                     /locus_tag="L1V38_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1314711.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30476..30661
                     /locus_tag="L1V38_000129"
     CDS             30476..30661
                     /locus_tag="L1V38_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314712.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30665..31840
                     /locus_tag="L1V38_000130"
     CDS             30665..31840
                     /locus_tag="L1V38_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1314713.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31833..33356
                     /locus_tag="L1V38_000131"
     CDS             31833..33356
                     /locus_tag="L1V38_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1314714.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33412..33696
                     /locus_tag="L1V38_000132"
     CDS             33412..33696
                     /locus_tag="L1V38_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1314715.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33683..34018
                     /locus_tag="L1V38_000133"
     CDS             33683..34018
                     /locus_tag="L1V38_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1314716.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34313..34939
                     /locus_tag="L1V38_000134"
     CDS             34313..34939
                     /locus_tag="L1V38_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314717.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35681..36517
                     /locus_tag="L1V38_000135"
     CDS             35681..36517
                     /locus_tag="L1V38_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBN1314718.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36581..37012
                     /locus_tag="L1V38_000136"
     CDS             36581..37012
                     /locus_tag="L1V38_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1314719.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(37074..38396)
                     /locus_tag="L1V38_000137"
     CDS             complement(37074..38396)
                     /locus_tag="L1V38_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBN1314720.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38550..40190)
                     /locus_tag="L1V38_000138"
     CDS             complement(38550..40190)
                     /locus_tag="L1V38_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBN1314721.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40523..40993
                     /locus_tag="L1V38_000139"
     CDS             40523..40993
                     /locus_tag="L1V38_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBN1314722.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            41215..42318
                     /locus_tag="L1V38_000140"
     CDS             41215..42318
                     /locus_tag="L1V38_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1314723.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            42602..43282
                     /locus_tag="L1V38_000141"
     CDS             42602..43282
                     /locus_tag="L1V38_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1314724.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43372..44406
                     /locus_tag="L1V38_000142"
     CDS             43372..44406
                     /locus_tag="L1V38_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1314725.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44420..44755
                     /locus_tag="L1V38_000143"
     CDS             44420..44755
                     /locus_tag="L1V38_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314726.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            44739..47219
                     /locus_tag="L1V38_000144"
     CDS             44739..47219
                     /locus_tag="L1V38_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314727.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            47275..48834
                     /locus_tag="L1V38_000145"
     CDS             47275..48834
                     /locus_tag="L1V38_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1314728.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            48831..50195
                     /locus_tag="L1V38_000146"
     CDS             48831..50195
                     /locus_tag="L1V38_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1314729.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50366..51436
                     /locus_tag="L1V38_000147"
     CDS             50366..51436
                     /locus_tag="L1V38_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314730.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51451..52119
                     /locus_tag="L1V38_000148"
     CDS             51451..52119
                     /locus_tag="L1V38_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314731.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52139..52717
                     /locus_tag="L1V38_000149"
     CDS             52139..52717
                     /locus_tag="L1V38_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1314732.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53118..54029
                     /locus_tag="L1V38_000150"
     CDS             53118..54029
                     /locus_tag="L1V38_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1314733.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54117..55034)
                     /locus_tag="L1V38_000151"
     CDS             complement(54117..55034)
                     /locus_tag="L1V38_000151"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBN1314734.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55236..55673
                     /gene="zapA"
                     /locus_tag="L1V38_000152"
     CDS             55236..55673
                     /gene="zapA"
                     /locus_tag="L1V38_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBN1314735.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            55732..56280
                     /locus_tag="L1V38_000153"
     CDS             55732..56280
                     /locus_tag="L1V38_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBN1314736.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            56395..58755
                     /locus_tag="L1V38_000154"
     CDS             56395..58755
                     /locus_tag="L1V38_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBN1314737.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            58842..59156
                     /gene="trxA"
                     /locus_tag="L1V38_000155"
     CDS             58842..59156
                     /gene="trxA"
                     /locus_tag="L1V38_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBN1314738.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59338..61116
                     /gene="uvrC"
                     /locus_tag="L1V38_000156"
     CDS             59338..61116
                     /gene="uvrC"
                     /locus_tag="L1V38_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBN1314739.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61261..62160
                     /locus_tag="L1V38_000157"
     CDS             61261..62160
                     /locus_tag="L1V38_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314740.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62153..63415
                     /locus_tag="L1V38_000158"
     CDS             62153..63415
                     /locus_tag="L1V38_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314741.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            63576..65474
                     /locus_tag="L1V38_000159"
     CDS             63576..65474
                     /locus_tag="L1V38_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBN1314742.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(65804..66523)
                     /locus_tag="L1V38_000160"
     CDS             complement(65804..66523)
                     /locus_tag="L1V38_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBN1314743.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            66860..67192
                     /locus_tag="L1V38_000161"
     CDS             66860..67192
                     /locus_tag="L1V38_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314744.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67179..69182
                     /locus_tag="L1V38_000162"
     CDS             67179..69182
                     /locus_tag="L1V38_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBN1314745.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69201..69671
                     /locus_tag="L1V38_000163"
     CDS             69201..69671
                     /locus_tag="L1V38_000163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBN1314746.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            69692..70276
                     /locus_tag="L1V38_000164"
     CDS             69692..70276
                     /locus_tag="L1V38_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBN1314747.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70291..71277
                     /locus_tag="L1V38_000165"
     CDS             70291..71277
                     /locus_tag="L1V38_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBN1314748.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            71267..71578
                     /locus_tag="L1V38_000166"
     CDS             71267..71578
                     /locus_tag="L1V38_000166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBN1314749.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            71600..73381
                     /locus_tag="L1V38_000167"
     CDS             71600..73381
                     /locus_tag="L1V38_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBN1314750.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73374..74750
                     /locus_tag="L1V38_000168"
     CDS             73374..74750
                     /locus_tag="L1V38_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBN1314751.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            74757..75392
                     /locus_tag="L1V38_000169"
     CDS             74757..75392
                     /locus_tag="L1V38_000169"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBN1314752.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            75422..76777
                     /locus_tag="L1V38_000170"
     CDS             75422..76777
                     /locus_tag="L1V38_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBN1314753.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(76969..78363)
                     /locus_tag="L1V38_000171"
     CDS             complement(76969..78363)
                     /locus_tag="L1V38_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1314754.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            78455..79426
                     /locus_tag="L1V38_000172"
     CDS             78455..79426
                     /locus_tag="L1V38_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBN1314755.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            79423..80205
                     /locus_tag="L1V38_000173"
     CDS             79423..80205
                     /locus_tag="L1V38_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBN1314756.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(80374..80745)
                     /locus_tag="L1V38_000174"
     CDS             complement(80374..80745)
                     /locus_tag="L1V38_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1314757.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            80879..81322
                     /locus_tag="L1V38_000175"
     CDS             80879..81322
                     /locus_tag="L1V38_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBN1314758.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(81365..82174)
                     /gene="yidA"
                     /locus_tag="L1V38_000176"
     CDS             complement(81365..82174)
                     /gene="yidA"
                     /locus_tag="L1V38_000176"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBN1314759.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82193..83560)
                     /locus_tag="L1V38_000177"
     CDS             complement(82193..83560)
                     /locus_tag="L1V38_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1314760.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(83544..84374)
                     /locus_tag="L1V38_000178"
     CDS             complement(83544..84374)
                     /locus_tag="L1V38_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBN1314761.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            84537..84974
                     /locus_tag="L1V38_000179"
     CDS             84537..84974
                     /locus_tag="L1V38_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBN1314762.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85050..85670
                     /locus_tag="L1V38_000180"
     CDS             85050..85670
                     /locus_tag="L1V38_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBN1314763.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            85859..86365
                     /locus_tag="L1V38_000181"
     CDS             85859..86365
                     /locus_tag="L1V38_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBN1314764.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            86382..87281
                     /locus_tag="L1V38_000182"
     CDS             86382..87281
                     /locus_tag="L1V38_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBN1314765.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            87368..88252
                     /locus_tag="L1V38_000183"
     CDS             87368..88252
                     /locus_tag="L1V38_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1314766.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(88444..88515)
                     /locus_tag="L1V38_000184"
     tRNA            complement(88444..88515)
                     /locus_tag="L1V38_000184"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(88480..88482),aa:Arg,seq:ccg)
     gene            88575..89909
                     /gene="rpoN"
                     /locus_tag="L1V38_000185"
     CDS             88575..89909
                     /gene="rpoN"
                     /locus_tag="L1V38_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBN1314767.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            90058..91149
                     /locus_tag="L1V38_000186"
     CDS             90058..91149
                     /locus_tag="L1V38_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBN1314768.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            91190..92191
                     /gene="gap"
                     /locus_tag="L1V38_000187"
     CDS             91190..92191
                     /gene="gap"
                     /locus_tag="L1V38_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1314769.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            92301..93491
                     /locus_tag="L1V38_000188"
     CDS             92301..93491
                     /locus_tag="L1V38_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBN1314770.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            93595..94350
                     /locus_tag="L1V38_000189"
     CDS             93595..94350
                     /locus_tag="L1V38_000189"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBN1314771.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            94466..95764
                     /gene="eno"
                     /locus_tag="L1V38_000190"
     CDS             94466..95764
                     /gene="eno"
                     /locus_tag="L1V38_000190"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBN1314772.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            96163..97302
                     /locus_tag="L1V38_000191"
     CDS             96163..97302
                     /locus_tag="L1V38_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBN1314773.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        32310 a        16636 c        20196 g        28204 t
ORIGIN      
        1 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
       61 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
      121 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
      181 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
      241 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
      301 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
      361 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
      421 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
      481 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
      541 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
      601 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
      661 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
      721 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
      781 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
      841 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
      901 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
      961 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     1021 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     1081 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     1141 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     1201 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     1261 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     1321 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     1381 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     1441 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     1501 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     1561 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     1621 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     1681 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     1741 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     1801 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     1861 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     1921 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     1981 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     2041 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     2101 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     2161 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     2221 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     2281 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     2341 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     2401 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     2461 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     2521 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     2581 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     2641 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     2701 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     2761 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     2821 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     2881 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     2941 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     3001 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     3061 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     3121 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     3181 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     3241 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     3301 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     3361 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     3421 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     3481 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     3541 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     3601 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     3661 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     3721 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     3781 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     3841 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     3901 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     3961 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     4021 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     4081 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     4141 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     4201 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     4261 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     4321 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     4381 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     4441 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     4501 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     4561 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     4621 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     4681 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     4741 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     4801 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     4861 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     4921 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     4981 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     5041 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     5101 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     5161 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     5221 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     5281 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     5341 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     5401 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     5461 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     5521 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     5581 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     5641 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     5701 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     5761 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     5821 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     5881 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     5941 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     6001 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     6061 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     6121 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     6181 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     6241 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     6301 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     6361 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     6421 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     6481 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     6541 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     6601 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
     6661 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
     6721 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
     6781 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
     6841 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
     6901 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
     6961 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
     7021 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
     7081 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
     7141 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
     7201 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
     7261 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
     7321 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
     7381 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
     7441 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
     7501 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
     7561 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
     7621 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
     7681 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
     7741 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
     7801 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
     7861 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
     7921 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
     7981 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
     8041 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
     8101 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
     8161 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
     8221 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
     8281 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
     8341 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
     8401 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
     8461 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
     8521 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
     8581 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
     8641 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
     8701 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
     8761 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
     8821 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
     8881 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
     8941 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
     9001 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
     9061 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
     9121 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
     9181 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
     9241 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
     9301 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
     9361 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
     9421 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
     9481 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
     9541 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
     9601 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
     9661 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
     9721 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
     9781 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
     9841 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
     9901 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
     9961 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    10021 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    10081 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    10141 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    10201 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    10261 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    10321 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    10381 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    10441 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    10501 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    10561 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    10621 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    10681 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    10741 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    10801 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    10861 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    10921 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    10981 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    11041 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    11101 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    11161 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    11221 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    11281 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    11341 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    11401 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    11461 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    11521 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    11581 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    11641 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    11701 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    11761 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    11821 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    11881 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    11941 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    12001 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    12061 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    12121 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    12181 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    12241 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    12301 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    12361 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    12421 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    12481 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    12541 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    12601 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    12661 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    12721 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    12781 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    12841 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    12901 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    12961 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    13021 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    13081 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    13141 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    13201 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    13261 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    13321 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    13381 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    13441 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    13501 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    13561 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    13621 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    13681 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    13741 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    13801 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    13861 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    13921 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    13981 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    14041 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    14101 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    14161 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    14221 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    14281 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    14341 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    14401 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    14461 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    14521 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    14581 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    14641 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    14701 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    14761 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    14821 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    14881 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    14941 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    15001 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    15061 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    15121 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    15181 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    15241 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    15301 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    15361 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    15421 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    15481 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    15541 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    15601 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    15661 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    15721 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    15781 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    15841 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    15901 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    15961 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    16021 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    16081 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    16141 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    16201 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    16261 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    16321 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    16381 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    16441 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    16501 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    16561 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    16621 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    16681 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    16741 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    16801 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    16861 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    16921 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    16981 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    17041 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    17101 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    17161 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    17221 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    17281 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    17341 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    17401 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    17461 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    17521 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    17581 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    17641 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    17701 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    17761 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    17821 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    17881 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    17941 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    18001 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    18061 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    18121 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    18181 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    18241 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    18301 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    18361 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    18421 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    18481 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    18541 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    18601 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    18661 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    18721 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    18781 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    18841 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    18901 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    18961 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    19021 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    19081 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    19141 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    19201 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    19261 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    19321 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    19381 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cgtcctacat
    19441 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    19501 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    19561 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    19621 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    19681 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    19741 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    19801 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    19861 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    19921 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    19981 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    20041 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    20101 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    20161 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    20221 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    20281 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    20341 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    20401 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    20461 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    20521 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    20581 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    20641 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    20701 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    20761 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    20821 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    20881 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    20941 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    21001 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    21061 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    21121 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    21181 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    21241 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    21301 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    21361 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    21421 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    21481 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    21541 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    21601 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    21661 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    21721 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    21781 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    21841 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    21901 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    21961 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    22021 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    22081 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    22141 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    22201 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    22261 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    22321 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    22381 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    22441 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    22501 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    22561 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    22621 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    22681 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    22741 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    22801 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    22861 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    22921 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    22981 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    23041 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    23101 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    23161 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    23221 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    23281 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    23341 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    23401 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    23461 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    23521 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    23581 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    23641 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    23701 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    23761 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    23821 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    23881 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    23941 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    24001 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    24061 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    24121 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    24181 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    24241 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    24301 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    24361 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    24421 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    24481 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    24541 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    24601 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    24661 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    24721 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    24781 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    24841 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    24901 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    24961 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    25021 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    25081 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    25141 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    25201 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    25261 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    25321 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    25381 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    25441 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    25501 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    25561 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    25621 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    25681 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    25741 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    25801 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    25861 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    25921 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    25981 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    26041 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    26101 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    26161 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    26221 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    26281 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    26341 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    26401 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    26461 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    26521 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    26581 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    26641 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    26701 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    26761 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    26821 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    26881 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    26941 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    27001 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    27061 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    27121 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    27181 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    27241 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    27301 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    27361 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    27421 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    27481 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    27541 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    27601 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    27661 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    27721 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    27781 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    27841 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    27901 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    27961 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    28021 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    28081 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    28141 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    28201 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    28261 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    28321 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    28381 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    28441 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    28501 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    28561 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    28621 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    28681 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    28741 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    28801 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    28861 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    28921 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    28981 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    29041 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    29101 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    29161 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    29221 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    29281 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    29341 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    29401 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    29461 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    29521 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    29581 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    29641 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    29701 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    29761 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    29821 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    29881 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    29941 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    30001 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    30061 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    30121 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    30181 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    30241 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    30301 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    30361 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    30421 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    30481 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    30541 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    30601 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    30661 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    30721 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    30781 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    30841 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    30901 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    30961 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    31021 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    31081 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    31141 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    31201 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    31261 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    31321 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    31381 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    31441 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    31501 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    31561 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    31621 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    31681 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    31741 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    31801 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    31861 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    31921 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    31981 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    32041 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    32101 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    32161 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    32221 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    32281 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    32341 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    32401 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    32461 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    32521 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    32581 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    32641 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    32701 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    32761 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    32821 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    32881 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    32941 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    33001 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    33061 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    33121 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    33181 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    33241 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    33301 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    33361 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    33421 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    33481 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    33541 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    33601 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    33661 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    33721 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    33781 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    33841 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    33901 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    33961 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    34021 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    34081 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    34141 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    34201 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    34261 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    34321 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    34381 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    34441 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    34501 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    34561 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    34621 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    34681 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    34741 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    34801 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    34861 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    34921 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    34981 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    35041 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    35101 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    35161 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    35221 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    35281 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    35341 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    35401 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    35461 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    35521 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    35581 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    35641 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    35701 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    35761 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    35821 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    35881 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    35941 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    36001 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    36061 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    36121 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    36181 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    36241 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    36301 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    36361 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    36421 tttgatcaat ctttacaatg ctttcgtcat cttacaaaca ttaggagaat ctagactaac
    36481 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaggagtata ctgtgataaa
    36541 aaaattcatt taaaaaaata aaaattggct ggtgatttgg atgttgcggg aaatgcgttt
    36601 aggagatgca gaagcactac gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt
    36661 aaccgttacg gtgagacaaa tgaagaaact gttgaaggag ccagaaaaaa attttttctt
    36721 ggtctatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    36781 atcgattttc agcgatccga tgttcaatat tatggcactt gctgtgtcta aacatgctga
    36841 aaaaagagga atcggaaagg ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat
    36901 atcagcaata agacttaatt ctgcagaata cagagtagaa gcacaccgat tttatgaacg
    36961 catcggttat cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatttttat
    37021 caaaaaatac ctggtcatca agccgatact tgatgatcag gtattttttt tgactaagaa
    37081 agtaattgca tcaagaaacc tgagatgatc aaaacgatgg caccaccaag ccgattgccc
    37141 atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacagc tacatttcct
    37201 gtaccaccca tcgagttgtt gcataagcca gcagtaatag ttgattcgat tggatataaa
    37261 ccaaacaaac gaccgacaaa tcctgaaact actgaaatcg cgataacact tgtcaaacat
    37321 aagacaacaa attgccatgt caaagcagaa gccaatacat ttagattcaa taacgcaata
    37381 ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttgtt gaacatgata
    37441 gctgcatctt cgtaatattc tggtaatagg tttgcgattt tacagataac aacgataatg
    37501 atcatgaatg cgtaagcatg gactttagga acaaaatagt tacagatttg tcctaagatg
    37561 aagaaagtca atgataccat caaaccgaca cctaattgtg gaatggaagg ttttacattt
    37621 ctaggttttc catcgccaag gtcgcctttt tccattaatt taccattacc gttgaatttt
    37681 ggcattgatt gtcccgcacg agcaactaac gctgcaccaa tgatagctag gacatttgtc
    37741 attgctgtcg caggaatcag gcgggaaatg atagaagaag cgtccgtacc taaaacattt
    37801 gcataaatcg ttgataaagg tacagctccg gctccaacac caccagccat tgcgggcaat
    37861 gagatatata aaacggaatt tgcaaaacca tttccgataa gcatacctac gagtcctacg
    37921 gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac agaagctttc
    37981 atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc aatataaaag
    38041 tctaaaaagc ccatattgct gacaaagttt tctgtggatt ttactacata ctcaggtaag
    38101 atcccaaatg tagcaatcgc ggcagaggca aagatcgcaa aaacggagcc accacctaaa
    38161 taacttttga cgatagggat ttttgttccg ataaaatgaa ataaattacc gaaaatgacc
    38221 aaaacagcga ttgggccaat catattcgtc ggtaattttc ctaaagccat tgcaatgatc
    38281 aggacaagga ccatgatcaa ataaaggggc aaacttacgc cggtaatttt tgttgaccaa
    38341 aacccttctt ttttcttttc ctcaactgca gttgcggttg ttgttttttg tgccattttt
    38401 acagatcctt tcttattctg tatcgtatga aaaaagccaa agagaagcgg caaaagagca
    38461 gtagttggct ggctgctgtt ttgccgcagt cgcttttttc tttttagacg tcatacaaag
    38521 tttctgtatg ttcttttact ataacaatct taatcttcta aagatttata ttcaggaacc
    38581 catttagcag attcaacagc ttctttgata tccgtgattt cttcacgatt caatttttgt
    38641 gcaacaactg attttgcgac agtttcagca atcgtttgag agaattcagt gatttttgct
    38701 actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc taatgctcga
    38761 ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat caaaccaagc
    38821 cctaaacctg ggtacatcaa cgcattattt gcttgaccga tttggtaagt tacaccgtta
    38881 tattccacat cagcagcagg gatacctgtt ccaactaaag cttttccgtc cgtccattca
    38941 atcaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg catgatgatt
    39001 ggacgtgggg tatgagccgc catttctttc acgatttctt cagtgaatgc tccaggttgg
    39061 gtagaagtac cgatcatgat cgttggatgg attgctttta caactgcttc taagtttgtc
    39121 aattcatcag cattagtgaa ttctgagcgt ttacgagcga atgggatttg accaggagtc
    39181 aatccttttg tatcttcaaa caataaaccc tgtttatcta cttgatagaa atgttggcgt
    39241 gcttcttctt caggtacacc ttgacggatc atttcatcta aaaggatgtt tgcgatacct
    39301 acaccagcag taccagcacc aaatgtcaag atcgtttgat ctttcaattg ctcacctgat
    39361 atattcaatc cacctaatac accagctagt acaacgattc ctgtgccttg gatatcatca
    39421 ttgaaagtag tgattttatc ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca
    39481 aaatcttccc aatgtaataa caattctggg aataattcag tagctgattg aacgaattga
    39541 tcaatgaatt cgtagtaagt ttcgccttct acacgagcat gacgattccc taagtataat
    39601 ggattattca ataattcttc gttattagta ccagcgtcga ttgatacagg caagacttgt
    39661 gcaggattga taccagccgc agcagtgtag accatcaatt taccgatagc gatgtcaaca
    39721 ccgttcacac cccagtcacc catacctaag attccttctg catctgtcac aacgatcaaa
    39781 cgaatgtcgc gtccatctgc tgcgtttttc aaacttgctt tgatattttc tggttcgtcg
    39841 attgaaagaa atgcagcatc ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa
    39901 tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc gcccatcaat
    39961 ttataaaaca atgtccggtt cgtattgaat agattcatta agaagatacg tttttccaaa
    40021 tcggtctgtt tgcttaagta ttgaccgtaa gcttggacag attgttgttc caatgtttgg
    40081 acagtacttg gaagcatacc agtgattccg tattttgccc gttcttcttt tgtaaaagct
    40141 gttcctttat ttagaaaagg attatttaat aagtttagcc ctgtaagcat gaatgattcc
    40201 tcctaagttt taatacaaac gaagtatagg agtcagatga ggatatagtc aaaaagagca
    40261 ggtataataa attttattta tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt
    40321 tgttcttttt atatcaacaa tccttgcttg attactatgc gtatctctta tatgctaaag
    40381 aaagaaaagt agaagaataa aggatatgtt agatagataa atagaatctc tgaagaataa
    40441 atcacgtgat cgtgacgata aaatacactt acgtcaggtg ataaaaaata cataagtaga
    40501 aaactaagag gaggaacaga aaatgaaaga agttcaattg atcagaaaaa gcgaactatc
    40561 agaaggtggt tgcaatgcat gcggcgtagt agaagcaaca agctatacat taaagcttgg
    40621 tgccaacaaa gcgataatct ctgagttgac agtaggcggt cttgtggaca gtctggcgct
    40681 tgctgaaggt tttattggag aagatattta tgagatgttt tcagaaatcc gtcagttaaa
    40741 aaaaggggaa aactgcatag aggttcatca tgagagcccg aatgtgagat tcaaacgtgg
    40801 tgataatgag atgatcttca ataatcatgt gtccgatcac accgagctat atggaatcgt
    40861 gaatcaaata ctaactgagc tttttggatt gggaccttat gcgttcaagg aagaaaacgg
    40921 taatccaaaa ttaaacgaag aatggcaaga aacgattgaa atacaaagaa acaacccgca
    40981 cttatttcaa taggcatcca cagtatttcg taaaagggac tttgacacga cttttgtcaa
    41041 agtcccatcg ttttttatct atttgtgttc taaacatttc tttcagagta gtaacaactg
    41101 gaatgactga aatgtaaaca gattatttgc ctgtatcaat acggaagagt aatataaagt
    41161 gtgtaaacgc tatcatatta ttcattcaat tttttataga gggaaggcat tgaaatggaa
    41221 aaaacgtatc aagcaggtac aaatgaagga atagtggatt ttatcaatat ggaagattta
    41281 gaaatagccg cttcacaagt gattccagct ggtggttatg gttacatcag cagtggtgct
    41341 ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcagct gattattcct
    41401 catgtattaa aagatgtaga attacccgat acaactacac attttgacaa agaaacgctg
    41461 actgcaccaa tcatcatggc accagttgct gctcatggct tagctcatgt gaaggcggag
    41521 aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag ttcttacgct
    41581 tcttgtacat tagaagagat aagagaagca ggcggggaga aagcaccgca atggtttcaa
    41641 ttttatatga gcaaagatga tgggatcaat ttggatattc ttgaagtggc caagcgtaat
    41701 ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg tgaaacagac
    41761 cgcagaaatg ggtttacctt cccactgcca atgccgatcg ttcaggctta tcaatcagga
    41821 gtaggccaaa cgatggatgc tgtgtacaaa tcttccaaac agaagcttag tccaaaagat
    41881 gtagaattta ttgctgctca ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa
    41941 gaagatgtct atcgttcatt agaatctggt gctggcggaa tctgggtatc taatcatggt
    42001 ggccgtcaac tagatggtgg tccagcagcg tttgattcgt tgcaatatgt ggcagaagca
    42061 gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgcggaca gcatgttttc
    42121 aaagcaatcg catcaggtgc agatcttgtt gctattggca gacccgttat ttatggattg
    42181 tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac agaattggaa
    42241 atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt
    42301 gagaatcgtt ttatttaaga aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc
    42361 gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa cgaaaaaata
    42421 aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta aacgatttta
    42481 ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga tgaattcatg
    42541 aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg agtgatttat
    42601 tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag gcggcttggc
    42661 aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct ttactgaacc
    42721 aacaaatacc gtggagcctc ttaaccctac tgatccttca aaaccagtag agccagcaga
    42781 tccggaaaat ccagcaactg gccagacagg tcctttaaca ctggatgtag ttcccgaatt
    42841 gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa
    42901 aaacgataca ccttatctcc aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc
    42961 acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac aagttttgca
    43021 aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata acgaatccac
    43081 tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga caccaatatt
    43141 tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc cagcaaatat
    43201 cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga cttggaacct
    43261 cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg tgaaaatact
    43321 ataggtgaag gattttttac cgcagttttt gttgaaagga tgtggtggac aatgaatcaa
    43381 agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat ttttccgtca
    43441 atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt tccagagaac
    43501 caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca aaatcagaca
    43561 ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt ctctgtcaat
    43621 ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc aacgttagat
    43681 gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta
    43741 tcagcacatg cagaaacaac tgtacctata gaagtgaaaa tcccagcaaa aagctttaag
    43801 ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac agaaaatgct
    43861 acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa
    43921 agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga cgaggtcaac
    43981 gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat cagcaatttg
    44041 atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac gtctaatgca
    44101 tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg tgataaagca
    44161 aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa tgaatggcga
    44221 tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt
    44281 tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc tgcagttcta
    44341 gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca
    44401 acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta ttgcaagttt
    44461 gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag gtacgattac
    44521 attttatgat ctaagtccaa ttccgcatcc aagtggttca gtcaatggcg catcaaaaca
    44581 gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc cggagacgaa
    44641 tgaacaaaag atccgttttc tttatttgat cattggtata gaattatggc ttcttgcgtg
    44701 gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa aataaatttt
    44761 cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt atcttttcac
    44821 cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca tacacgtatg
    44881 aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac
    44941 taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat ggttcaaatg
    45001 atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg
    45061 tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc atcaatttgc
    45121 cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac gcctacttgt
    45181 atattgccgg tgcccccatc aaggttacta gcggaagttt attatcagca ggaagccata
    45241 ccttgcgttt tgggatgggg tcgtgggata caaatactct attgacagat attattgcta
    45301 ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat gttacagcta
    45361 atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac aaaattttga
    45421 ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt gatttttatg
    45481 attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca gctgcaggta
    45541 gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca ttttctgcaa
    45601 gtgcagagat aaatacgtgg aatagttaca tctcaccaag tgattcaaca ggaaaatata
    45661 atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt ccaggctcta
    45721 ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag ttgccattta
    45781 gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa ggagcaatac
    45841 tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc gtgtacagtg
    45901 ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg gagcagtaca
    45961 agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg ggaaagctcc
    46021 tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta aaaaagggtt
    46081 cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga tggacagatc
    46141 aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact tctacactac
    46201 ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat gtacttacta
    46261 acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc accactcttc
    46321 ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta aaaaacctta
    46381 gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg attcaagaaa
    46441 atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa atcacgatct
    46501 cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt acaactatcg
    46561 cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc aaaataggag
    46621 ataccattca tcttacttac aactatcaat taaatactgt agatacttct ttacaatccg
    46681 tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca gatggtgcta
    46741 agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc aaacaagaat
    46801 taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc aaaccgttga
    46861 agacaagtta ttatgaatca aaaggcgatt tttcttttga tgtgcgggat actcggcttc
    46921 caagcacgtc tccttggcaa ctgacaggta cattgacttc tttatttaag aatgatcaag
    46981 gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaag caattgattc
    47041 agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga gaggttctcg
    47101 ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg aatgctcaac
    47161 ctggcgcaac gtatcaaggc atggtcacat ggaaactgac agctgggcca accagctaag
    47221 tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc aaggatgaga
    47281 aggaaacttc tgctgttaaa atcagaaatg cttgaaggag tggacttgga acttttcagt
    47341 ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt agaggaaaaa
    47401 ggagaggttt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc taccttgaaa
    47461 gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga aattgttatc
    47521 caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga tgtttattat
    47581 cattgttact tgcgctattc tacaaaatat cagatacttc tttatctgtt ggaaaatggc
    47641 tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac tttgtctcgc
    47701 agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg
    47761 ctgaccggtc cagaaagtca aattcgttat ttttatttcc aattattttg gtttggacgt
    47821 ccctatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt tttagatctg
    47881 ctgcaaaaag agtttagttt tgctattaca gaagaaggac gattgaaatt tgaaatatgg
    47941 ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat
    48001 cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac atttttgacc
    48061 cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt tttttatctt
    48121 ttcatgatca gtaactttac attagataca cataactcgc atgtccagga gtttttgata
    48181 agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa acaatcgata
    48241 gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat tgcgttgaca
    48301 gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat ttttggccaa
    48361 gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt tttatgtgaa
    48421 agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga ggaaaatgcc
    48481 cgctttgaat tatttgctcg ctatgcatct attttacgga cgctgatcaa gcagttagaa
    48541 ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa
    48601 gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga atacgagaaa
    48661 gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc acagaagtcc
    48721 gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta tttgaaccaa
    48781 tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac atgaaaatcg
    48841 tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga aaacttcaac
    48901 cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc tatgtttcaa
    48961 atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt gcccataaca
    49021 tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta actgaacttg
    49081 atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag accataacct
    49141 atgataaatt aatcgtagcg acaggttcct ctcctgtcac cttgtataaa caaattgaag
    49201 ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt gccgctttaa
    49261 aagaagcaaa agaagtagtg atcttcggtg ctggttacat tggattggaa ttagcagatg
    49321 ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat gttttatcaa
    49381 gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact aagcaaataa
    49441 atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg
    49501 tacaacttct gtctcaaaca ataaaggcag atatggtcat tttttctgcc caaactcgtc
    49561 ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact gtgatagtca
    49621 atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc gtcccagtca
    49681 gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct gtacatatgg
    49741 caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc agacaaaaga
    49801 taacagcagc agtcattata gactactttt taggaactgt agggctgaca gaagatgaag
    49861 cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta tttccacaat
    49921 acgacgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat acattagaaa
    49981 taattggcgg acagctgata agccaagaat tcttattatc agatttgaac ctgcttgcgg
    50041 atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt ggatttctgt
    50101 ctgaatacac ctctcgtttt cactacctca atgagttagc ttttaaagta ctagctaaga
    50161 gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct tttattgtgt
    50221 ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga aatagcggaa
    50281 gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa
    50341 tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta tgcattcaaa
    50401 gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg tatttttttt
    50461 gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca agtgggaggc
    50521 agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca tgattactaa
    50581 gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaaa cacctggagt
    50641 cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct tcggtatcga
    50701 taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata acgatgatga
    50761 ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccataggag atacagttaa
    50821 gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg ccaaattcaa
    50881 tgtctcacca gttctctata caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga
    50941 agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa tcagtaattt
    51001 acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac ctggatataa
    51061 tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg cggctattgt
    51121 gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg gtgtaatgaa
    51181 agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa cattcatttt
    51241 atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc ttgttctacc
    51301 tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct tgttgatgtt
    51361 agtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa tcgatccgtt
    51421 gaaggcaatt ggataagaag gaggaagaac atgaaagcaa tagaatttaa agaagtagaa
    51481 aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac catgagtatc
    51541 gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag tacttttttg
    51601 actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa tgatcaagaa
    51661 ttcagtaatc aaaaagaaag cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt
    51721 ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt attagtagat
    51781 aagattaaac atgaacatcg tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg
    51841 gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca aagggtcgca
    51901 atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc aactgctagt
    51961 ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc aaaagacaaa
    52021 aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg cgatagaata
    52081 tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag gtggaaaaat
    52141 ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga ctgacttgtt
    52201 tatgtccaag ggatatctcg gcacttcaac aagagaaatc gcacaaaaag ttgggatcac
    52261 ccagcccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg cagttttaga
    52321 aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg
    52381 atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc tggtcgattt
    52441 gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag atcatctttt
    52501 ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag caaaccaatc
    52561 tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct tagtgttagc
    52621 accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat
    52681 cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag ggagaaaata
    52741 gttaggtgaa gaagcaagat atgacgaaga tcgttatatc ttgcttcttt atataggtag
    52801 tttttcataa agacaaattt gttattctct catgattatc agggtatatt tttatttatt
    52861 atgtcggtgt tccaggaagt gttttaattt aataacgaag aaattaattg tttgtagaat
    52921 gaaggaaact atttattggg tagatgaatc accacgaata gtcaaaagga gatttcagga
    52981 tatgccaaaa atgaaaaaaa tcattttagc agtaatgtta ttttctacgg ttatatcttt
    53041 tacagcccct tttttgctta cttaagctga ttttaagttt tggcccttag tctggatcta
    53101 cgaggtgaga gtcaagaatg aaaaaaataa ttggagcttt tgtatttgca atcattatca
    53161 ttattatctg ttttcaaata gatgtttttg gtcaaaaaaa gatagttgga caaacggtca
    53221 gcagtacgaa cagtacggtt acaaagacaa aggaatcatt tgatgataca gaacaagaga
    53281 cattaatcaa aatcggaaaa aatgaccgta cactatatac agatgactcg ctaactaccc
    53341 cacttgcaac tataaacggc ggagagctgg cggagtttct ttctgaaaca aaaaatgctt
    53401 atcagatcaa gacaaatgat ggctatactg gatatttagc cctcgaagat ggaaccaaag
    53461 tcacaaagaa tatacaaaca aaaccggaag agctatctga tgcagtgatt gtattagatc
    53521 ctgggcatgg cggaaatgat actggggcat taagcaatga tgaacaaaca gaagaaaaag
    53581 atataacatt aagtacagcc ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg
    53641 tttatttgac ccatactaca gatgaattag tacagcttgg agatatatgc gactacagtg
    53701 aagaaaaaaa ggcagatgtc tttatcagtt tacacgcaga ctctacggaa tatgcgaatg
    53761 aagcaactgg aatcacgaca tattattact atggacaaga ggaaacatta gcacagacaa
    53821 ttgctgactc cttcactgat ctgcctctgg attcaagagg aatctccact gggaactatc
    53881 aagttcttcg agaaaatctt caaccttcta ttttaatcga gatgggttat atgaataatg
    53941 atagtgattt aaaggaatta gtaacagaca gttatcagca gcagattgct gcaagtttga
    54001 cacaagcatt gaccacttat tttcagtaat aaataagccc agccaaacaa aaatagctcc
    54061 tcatattttt cgtttggccg ggcttattat cgcagatgca agcttttgaa caccgtttat
    54121 ttttttagta gcttcaaagc tttttctgta tttgcaaagt gaagtttggc atatttttca
    54181 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    54241 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    54301 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    54361 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    54421 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    54481 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    54541 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    54601 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    54661 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    54721 ggaccgaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    54781 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    54841 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    54901 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    54961 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    55021 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    55081 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    55141 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    55201 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    55261 aagcggtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    55321 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    55381 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    55441 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    55501 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    55561 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    55621 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    55681 ttatcaaaat aagaaaaatt taaaaaaagt tagaagagaa aggaacgtag catgctgagt
    55741 ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg cgggtttgct
    55801 ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca gcatttttac
    55861 aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac gccaacatca
    55921 aagttagcat tttttgatca ggtatttgcc tttcacctag atgaagcttt ttatgcagga
    55981 actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt gggggttttt
    56041 gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc aggaggcatc
    56101 ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact tgcctttgtt
    56161 ccattagatg tggtccaaaa tcaattcggc gagcatagtt tcgctcgctt tatcgttgag
    56221 agaacgccat ttcttaccaa caagatgtat gagctttggg taacgaatat tttgaattaa
    56281 ggaaaatagt gctggaaaat atttcgtttt ttgtacagag tagattattt aagaaggctg
    56341 cgtagcgtat gtccggcaca gctctttttt catagtgaaa gataaggtga taaaatgaat
    56401 aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac agatggtcag acaatttgta
    56461 gtgactgcac aaggaaaaga agaactggca gaattggtac cagtgagcga ggaacaaacg
    56521 atcacaaact ggcttcaaga aactgaggat ggattgaaag tgcaacgtct gcgaggcggg
    56581 atccctatac ctaaacttga aaatatccgt ccccatatga aacggattga gatcggagca
    56641 gacttgaatg gagtggagct tgcacaagtt tccagagtat tgtctacgac aagcgaattg
    56701 aatcgtttca ttgatgatct ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg
    56761 gcagatcagt tagtcacgat ccctgttttg agccgccgtt taaaggaagc aatcgatgaa
    56821 gacggacgcg tgactgatga cgcttctcct gagttaaaga gcataagaca gaacattcgg
    56881 cgaagtgaac aagctgttcg tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag
    56941 tatttaagtg atgcgatcat caccatgcga aatgaccgct acgttatccc agtcaaacaa
    57001 gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa gtgcttcagg acagacttta
    57061 tttattgaac caaaacaagt ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct
    57121 gaacgaaatg agattcaacg tattttaagt gaactttctg ctgaacttgt tccccatcgt
    57181 caagaaatca tccacaatgc ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca
    57241 cgatttggta aagaagtaaa agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc
    57301 ttgaaacaag caagacatcc actgatcgat caggaaaaag tagtttctaa tgacatcaca
    57361 atcggaaaag actatcaagc catcgtcatt acaggaccta acacaggtgg gaaaacgatc
    57421 acgttgaaga ctttaggtct gttacaactg atggggcaag caggattacc gattcctgca
    57481 ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg cggatatagg agacgaacag
    57541 tcgattgagc aaagtctatc gaccttttct tctcatatga cgaacactgt agatatttta
    57601 tcaaaagtca atgaaaaaag tctggtatta tttgacgagc tcggtgcagg aacagatccg
    57661 caagaaggtg ctgctctagc aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat
    57721 gtgatggcaa caacgcatta tcctgaattg aaagtttatg gatataatcg ggcaaatacg
    57781 attaatgcca gcatggagtt tgatgtggat acattaagtc caacgtatcg tttgctgatt
    57841 ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc gattaggtct tgatacagaa
    57901 gttattgatg aagcgaagca gttgatgaat gatgagagcc aagatttaaa cgaaatgatc
    57961 acagatttag agaatcgccg gaaaatggca gagaccgaat atctggaaat gcgtcatttt
    58021 gtttctgagg cacaagaact tcacgatgat ttgaaagaag cttacagcta tttctttgaa
    58081 gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg
    58141 gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa tgcaacagca gattgggcaa
    58201 ggaaatgtga aagagcatca gttgatcgat gcaaagaccc aattagcaaa tctacatcaa
    58261 gaagaaactt tgaagaaaaa taaagtattg aagaaggcga aagaacaaaa aacgttgaaa
    58321 ccgggagacg aagtgttggt tacgacttac ggccaaagag ggacgctttt acgtaaaaac
    58381 gggaatcagt ggcaagtaga aatcggtata ttaaaaatga atgtgtccga agacgagctg
    58441 acgcctgttg ctcctcaaaa agagccgaca caacgagtta tccatgctgt acgatctgaa
    58501 tctagtagtc acgtgccgaa tcaattggac cttcgaggaa aacgatacga agaagcgcta
    58561 agtgaggtag atcaatattt ggattctgcc attctagctg gttatcctca agtgactatt
    58621 gtccacggaa aaggaacagg cgcacttcgc aagggaatta ctgattatct taaaaaccat
    58681 cggagcgtca aaagctttga gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt
    58741 gttaaattta agtaaagctt actaaaggta agcagatggt tcgctatcca agtatagaaa
    58801 tgctatacta gtcatagatt ttaaaaatgg aggtctttga tatgtcacaa gtaattacag
    58861 ataagacatt taatgaagaa acagataaag gacttgtatt gattgatttt tgggcaactt
    58921 ggtgtggtcc atgtcgtatg caagcaccga ttttggatca gttggaacaa gaatatgatg
    58981 aagaagaatt cagaattgct aaaatggatg tggatgaaaa tccagaaact cctcaacaat
    59041 tcggtatcat gagcattcca acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag
    59101 ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat cgatcaatat ttataaaaac
    59161 ttacagcaaa aataagctga gggtgggact gaatccagtt ccgtcctcgg tttttttgcg
    59221 gttgagttaa ggttattcaa attaatattt tttgagtata attacgttgt caggctggat
    59281 tgtttttttg acagacatgc tataataact ttaattgaat atgaagggga gtaccagatg
    59341 aacgaacgaa tcaaaaacaa attagcttta cttcctgatc agcccggctg ttacttgatg
    59401 aaagataaaa atggaacgat catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc
    59461 cgctcatatt ttactggtag ccataatacg aaaacggaac ggcttgttag tgaaatcgaa
    59521 gactttgaat acatcgttac agaatcgaat atcgaagcat tgctcttaga gatcaatctg
    59581 ataaagaaaa atgatcctaa atacaacatt atgttaaagg atgataaaac ctatcctttc
    59641 cttaagataa cgaatgaaaa atatccccgt ttggtgatta ctcgtaaggt actaaaagac
    59701 aaagcactgt attttggacc atatcccgat gtcggtgcgg cgaatgagac aaagaagatc
    59761 ctcgatcgat tatttcctct gagaaaatgc aaacctagtc agacgaagga gccttgtctt
    59821 tactatcatt tgggacaatg tctgtgtcct tattatttcg acgtagatcc gaaagtctat
    59881 acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca
    59941 gagatccatc agaaaatgga aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa
    60001 taccgagacc agatccgtgc cattgagaca atcatgactc gccaaaaaat gacaaatact
    60061 gatttactgg atcgagatgt atttggttat gcgattgata aaggatggat gtgtgtccaa
    60121 gtgtttttcg taagacaagg aaagctaatt gaacgagatg tttcaatgtt tcctttctat
    60181 aacgaagcag aagaagattt cttgacttac ctcggtcagt tttatcagga aaatgagcat
    60241 ttcattccta aagaagtctt gattcctgat acgatcgaca agcccagtgt agaagctttg
    60301 ttagctacga aagtgctgca accaaaacga ggagaaaaga aaaaattagt tgaattggcg
    60361 agtaagaatg cctcagttgc tttgaatgaa cggtttgatc tgattgccag aaaacaggaa
    60421 cggacgatcg gagcagttga acgtttagga aacgcgatga atatcccgac cccaatacgt
    60481 atcgagtctt ttgataactc taatatcatg gggacgaatc ctgtggctgc gatggtcgta
    60541 ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat ataaaataaa aacagtcaac
    60601 ggaccggatg attatgcatc aatgagagaa gtcatctatc gcagatattc gcgagtgatt
    60661 cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg gaggaaaagg acaagtagat
    60721 gtggcaaaag atgtcttaga aaatcaatta ggaatcgata ttcctattgc tggcatggca
    60781 aaaaacgata aacataaaac aaatgagttg ctattcggta cagatttggc tgtagtaccg
    60841 cttgagcgaa attcaccaga gtttttctta ctccagcgaa tccaagatga agtccatcga
    60901 ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca gttttgcttc ccgattagat
    60961 gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg
    61021 aaaaatatca cagcagccac gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc
    61081 gcacaaaacg tatttgataa attacatcag gaatgaggaa agggcacttt acaaagaaag
    61141 taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa
    61201 taaatcgctt acgtctggtg tctaaggata tatgtgattt cttgaagaag gagtgaagaa
    61261 atgttagaag tcaaggatct tgttaaaact tttgggaact acacagctgt cgatcatgtc
    61321 tctttccaaa tccccgatgg aaaaatcatg gggctaattg gccaaaacgg ggctgggaag
    61381 acaacgactt ttcgtttgat cttggatttt ttgacacaag accaaggaga agtgttatgg
    61441 aatggccatc atcttgggga gaaagattat gatgtcatcg gttatcttcc ggaggaacgg
    61501 ggactttatc cgaaagtaac gattcaagac caactgcttt attttgcaga acttagaggg
    61561 aaatcaagaa aagagattga accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa
    61621 gggaaaaaga cggataaagt aaaatctttg tctaaaggaa atcagcaaaa agtccagctg
    61681 atcgccacgt taatccatga acctaaattg atcattttgg atgagccatt cagcgggtta
    61741 gatccggtaa atgctgaatt gctaaaagat ggaatattgg aattgaaaaa acatggttca
    61801 tgtgtcattt tttctagcca caatatggat aatgtagaaa aaatctgcga tcatttgatc
    61861 atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac atgagattcg tgaatcattt
    61921 ggccgtacga agttattctt ggaatctggt ttaagccaac aggaagtaga agaaatcgaa
    61981 ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag agattacctt agaagatcct
    62041 gaagctggga aagaaatctt tactcgtgcg actcagttcg gctacattcc tatgtttaac
    62101 cagcaaccgc caactttgga agagattttc aaattgaaag caggtgaaat cgatgcgtaa
    62161 gttttggatt attaccaaag atgtctattt aaaaaatgtt aagtcgattt ctttcttgat
    62221 catgatatta gtccctttta tcatgctggg tatcatttat gtagcaggaa actttgctca
    62281 acaaaatagt gatgtcaata aaatcggcgt attggctgat aatgagcaaa tcagtcagca
    62341 aatgagccaa gtcaaaacag atgattttga gttcaaagca gttgattctg aagaaaaagc
    62401 acaaaaagag ctttcggaag aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga
    62461 taagataaat gggatgcttt atagcgaaaa ttcattagga caaagtacac aactactgat
    62521 acaacaacaa ctgactggct tgcaatcgat gcttcgagcg agtcaattag gcatttcacc
    62581 agaagaagta gctagcttga gccaacaagc aagtttgact cgacaaaaag tcaattttga
    62641 ttcaaaagga aaaatgacag tcggagaaga taactcgaca gtccaatacg tcgtaagtta
    62701 tgtagcaacg attgtcttgt tcattattat tttgacgtat gcgcagatca ttgcacaaga
    62761 gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc ctgtccagta cgactgcaca
    62821 aaagcatttt tacggaaaat taacaggtgt tttacttgtt gcattaacgc aaatggcatt
    62881 atacggtatt atttttggta taggatacag tcaattcaaa gatatggaaa tggtcaaaaa
    62941 tatattagac ggtatctcat tggataactt gattggacca ttcttgtggt attctcttct
    63001 attcatgatc tttggcattt tgattttttc tgttttagca gctttatgtg gctctttggt
    63061 caacaaagca gaagatacag caaaagcaat tttgccagtg acttatctat ctctaggcgg
    63121 atacatgctt ggattgatac taggagcttc agatccaaac aatatcgtta ttcggatcac
    63181 ttcgtatatt ccattcttat cttcatatat tatgccggtt cgcttagcaa atgagacagt
    63241 cggtatgggt ggagcattga tttccttgtt ggtacttgta gccgtaacat tcttattgat
    63301 gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt tatagcgaag gcggattatg
    63361 gagttcattg aaacaatcga tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa
    63421 tcctaaaata cagaaggaag ctggacatct attgttccca gcttcttttt gtatagacct
    63481 attttattta ttttactata ttggatatat attcattgaa aatagtgtat aacaacttta
    63541 taatattgag tataccaatt tttggaggcg ttttaatgga ccgttattta gatttacttt
    63601 cagaaaaatt cccctcaacg gaggatgtca tcacggaaat catcaatctc gaagcaattt
    63661 tgcagcttcc aaaaggaaca gagttatttt tgagtgatat acatggcgaa tttcctgctt
    63721 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gacctttttt
    63781 ctgaacaaat gacggaaacg gatatcagcc aattcactat ttttacggct tatccagaat
    63841 atgcattaac gactgattgg tacaaagaac aagataaatc gcagctgatc catcatttga
    63901 tcgatctttt acggtttacg acagtcaaat atacccggtc aaaagttcga aaaggattgc
    63961 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgaccgt atcaatggaa
    64021 aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt gatgaaggaa gaagaaaaat
    64081 ttttaacgaa acttgcacag acgatccaaa aatctgtcat cgatcatttg catatcgttg
    64141 gagatatttt tgaccgagga actcaagcag ccaaagtgat ggatcgaatc atggattttt
    64201 cttctgtaga tatccaatgg ggaaatcatg atattttgtg gattggtgcg tattgcggct
    64261 ctgaggcatg tttactgaca cttttacgga ttgcagcacg ctataattat ttatttgaat
    64321 tagagaaaga atatgggttg aatttacgtc cattgttttc ttttgctcat caaacttatc
    64381 agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag
    64441 aattagaaaa aatccatcag gcactttcta tccttcaatt caaatcagaa catcagttat
    64501 tggatcgtcg acctgaattt aaaatggacg atcgtaaatt gctggaaaaa atcgactatg
    64561 aagcatcaac gattgattta gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa
    64621 cgatccagcc agatgatcca aaaaaattct tggaagagga acaaaaagtg attgatagtt
    64681 tgatgtattc attccagcac tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa
    64741 aagggggaat gtatctcacg aacaatcagc atgtgctgtt tcatggctgt atacctgtag
    64801 acgagaaggg acagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
    64861 tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga tctgactgca aaagaagatt
    64921 tagcaaccga tttgatttgg tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga
    64981 gtaaaatggc gacttttgaa cgttattttc tcacagagcc tcatacgcac gtcgagaaaa
    65041 gcaatcctta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttagcagaat
    65101 tcgacacaaa agaagaaggg tcagcaatca ttaatgggca cacgccagta aaagtaaaaa
    65161 aaggggagtc accgatcaaa gcaaatggaa aagtatttgt cattgacgga ggtttatcca
    65221 aagcttatca aaaaacgaca ggaattgccg gttattcact attatgcaat tcttatggtt
    65281 tccaaatcgt gacacattat ccgtttttgc ctattgaaca acaatttgca aaaaaatccg
    65341 accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc acgcaaactc aatcgtgata
    65401 caacaaaagg tatggaactg cagcagcaga ttacccagct caaaaggctg ttggactatc
    65461 gaaaggacga ttgagaagaa ttccagtgaa cattgttcca tagactggag actgagacaa
    65521 aagtcgtgtc gcagtctctt tttccggata aacggtgttc ttctgccaac tcctcggtca
    65581 caagtcacac tattcaacaa acatgaaaag ctgttttttg aaattgctcc ttgtgactca
    65641 gagttgaacg gcaggctcac gacctcttgg tataaacggt gttcaaaagc cagtttctcg
    65701 gtattaagcc aaatttatgc aaaaatgtga aaagccattt tcacaaaatt tttcttaata
    65761 ctcgaaacta aacagctttt tcacaacccc ctcagaaagt ctattaaaat tcattcacaa
    65821 agaaatcgaa taagcgctgt tcagatggat gtacacggtg ggtaagttcc ggatgccatt
    65881 gaacaccgag gattttatgc atatcatctt tgctttgaac cgcttcaatg agtccatcgt
    65941 tagaaaaagc gatggctttt aataaaggtg aaagatcttt gactgcctga tgatggtaag
    66001 aattcacaaa atatggatcg gggagaaggt tgcttaacaa actgtctgaa acaatcttga
    66061 cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc atgttttact gaccactttg
    66121 gatataatga aagatcttga taaagtgtac cttccaaaac gacattcaat agttggagtc
    66181 cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt
    66241 caaattggtc tcgttgaata tttgtttccg ttagctttgg atgaggatct tccatgtaaa
    66301 gttgtggact gacatcttga ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt
    66361 gaggagctga atctggagac atgactggca gaataagagg caatccttga gcatctaaaa
    66421 ctgcatccac gaatccttgc ggtgtatagc tcacttgatt tccttggaaa gtatctgttg
    66481 ctcgaatcag ttgatttccg gcaatgccga tgattggttt catttgtatt ccccctaaag
    66541 tagacttatt gtaacaagga tttaaaaaaa attaaactat gtaagacttg cccctatact
    66601 tatctgttct tgctgtgtta ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat
    66661 agttgaaaat attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc
    66721 gtaagcttca aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg
    66781 cctatactaa gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc
    66841 ttttttaaat cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc
    66901 agaagaagaa aatgaaaagc gtgctcaaac actgcggcag cagctgaaga tctatgcaac
    66961 agaaaaagag caggaattgg aaacgatcca aacaaactat cgacaacaac taaaacagtt
    67021 ggtggaagaa aaagaacaat ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa
    67081 agcagaagca gacaaggtgc aagcaacttt gaaagatcaa tatcaaaagc atcagagtca
    67141 agcgatcggt gcgatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa
    67201 aagtgaccct catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa
    67261 tccaaaacgt tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtggaga
    67321 agtattttcc agataccacg attattgata aagaagcaaa attaagcgct ttaggtaatc
    67381 ggttgaaaga catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa
    67441 agaaactcca tttgaaacgt caagaacttt ccttacaaga tttggaagcc aattattccg
    67501 aagaaaattt cataaataaa ttgaaagaag tccttgattt aaaagaaaag tgggaacaac
    67561 taactgaaga acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc
    67621 tggatattgc tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga
    67681 gtgcagcaaa ttttgaaagt ttcaaggaag aactgagtaa gcttgatgac gtttatatgg
    67741 aagaaataga ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag
    67801 ttgctgttat agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg
    67861 aacaaaatcc taaagaaaaa ctgcaagaga ccaagcagca attatccatt gttcacgagc
    67921 agcaaaagaa gataacgaca gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat
    67981 gggtagaaga agtcacactt gccgttgcag aacgagaaaa aataaaagaa cggtttatcc
    68041 atgcgactta tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc
    68101 tgcatgtgtt aaacgaaacc gtatcagaag aagatatata cgtcagtttc gaaacaccaa
    68161 actcagaaga gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac
    68221 cttttgaatt gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacac
    68281 cttggatgac accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttatg
    68341 gtttgctgat gctcattggg acaatactag ctcaaaaact acttgttcta ccacgcggga
    68401 tgaaacgttt cgtaaaattc tttgagattc tctcgatacc atcgatcatc tggggattga
    68461 tctacagttc atttttcgga cagtcattac caaaagaact gtttggcatc cgcttgcctt
    68521 tcccaatcct atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg
    68581 gtctgataca gattttggtt ggattatttg tggcagcaaa ggaaaatatc aggagaaaag
    68641 attacttgag tgctgtcagt gatggatttg cctggcaagg gatcctaatt gggatcgtta
    68701 ttgcgttggt tggtgccatg ttgataaaaa atacagcatt tgtttacctt ggcgctgggc
    68761 tatcgatcat tgctgcctta tgtatcttga tcgttccgat tatccaaacg ccgtctaaag
    68821 tcaaaggtgc tgccaaaggt gcgtataatc tttacggact gaccggctat atcggtgatt
    68881 tagtcagtta tacacgtttg atggcattgg gtatttcagg cggaagtatt ggagcggcat
    68941 tcaatatgct agttgctttc atgccgccag ctgctcgatt cagtgtaggg atccttttga
    69001 tcatcgcttt acacgcactg aatatgtttt tgacactgct aagtgcctat gtccatggcg
    69061 cacgattgca gtatgtcgaa ttttttggga agttttatac aggaggcgga cgtgcctttg
    69121 atccgctgaa aacggcggaa aaatacgtca acatcaatca caagaaaaaa aacaataaat
    69181 aattggagga tttttatata atgatggatt acttaattag tcaaaatggt ggaatggtat
    69241 ttgcggtatt agcgatggca acagcgacga ttttttcagg gatcggttca gctaaaggtg
    69301 ttggaatgac aggtgaggca gcagcagcat tgacaacaag tcaacccgaa aaattcgggc
    69361 aggctctgat tctgcaattg cttccaggta cgcaaggttt gtatggattc gttattgcct
    69421 ttttgatttt tatcaactta ggaaatgaca tgtcagttgt acaaggactg aactttctag
    69481 gtgcttctct gccgattgct tttacaggct tgttttcagg tattgcccaa ggaaaagtcg
    69541 cagcggcagg tattcaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt
    69601 ttgctgcgat ggttgaaaca tacgcgattt taggtttcgt tatttccttc ctattagtgt
    69661 tgaatgccta agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca
    69721 gatgaacgaa gcagcagagc aggaaagagc ggcgttagaa caagaagagc gaatgaagat
    69781 cgatcaaaac tttgaacaaa aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga
    69841 aaaacaaatc gaattactcg aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga
    69901 agtacgacaa gaaaatttga atgcgaagca ggaattttta agacgattgt ttgcagatgc
    69961 ggtaactgaa atggaaaatt gggatgaatc tgaacaaatc cagtttatca aaaatgcatt
    70021 gtattcatta cctttgacag gaaaagtagc attcattgct ggagaaaaat cagcagccta
    70081 tctttctcag acgttgttgg atgaatggaa caatgaactt ccctttatga tggttttaag
    70141 tgatgaaact gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa
    70201 ttttcttttc agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa
    70261 tcaattattc gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt
    70321 cgcggaagag agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat
    70381 tctgtcgaag cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac
    70441 ggatatgaat atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg
    70501 ttaaaggaat cagcaccgga gcctgaaatc gtttggatct atacgatgcg ttatactttc
    70561 cataatctga aggttttgac aaaagctgag atgacaaatc aaaatctgga ccatttgtat
    70621 atcgacgatg gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca
    70681 aatgaacttc ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag
    70741 tctaccattc ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga
    70801 cggcttgccg ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac
    70861 ttgaccaata tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg
    70921 acgacggtac tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat
    70981 aaagatatgg aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc
    71041 cctgtcatcc gtgagggaaa tattgatctc gtaaagcttg aacagttgaa agatgattat
    71101 ctaagttcat tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc
    71161 tttttgaacg caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga
    71221 agccatttcg aatcagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat
    71281 cggtgtagtt ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg
    71341 ttatggtaca accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta
    71401 tggcgtgatt tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta
    71461 caaggaacaa atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat
    71521 agggctggaa gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta
    71581 tgaaaaggag atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt
    71641 aatggctgag aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg
    71701 agttatcgga gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga
    71761 gacttctgga attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga
    71821 attaggacca gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt
    71881 tatggaaatc acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca
    71941 tgagaaaaaa tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga
    72001 tgttatcggg atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg
    72061 gataaaagga acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg
    72121 tgtcattgaa accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag
    72181 acgtagtcgg ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg
    72241 agtgattgat acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt
    72301 tggtgcaggg aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt
    72361 tgtctatgtg ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc
    72421 tgaattgatt gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa
    72481 tacatcaaac atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc
    72541 ggaatatttc cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg
    72601 ggcagaagca cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta
    72661 tccagcttat cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc
    72721 attaggatca gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg
    72781 aggggatatt tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg
    72841 tcttgattcc agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta
    72901 ttctctttat tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc
    72961 atccatggtc accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt
    73021 gcgtttggta gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa
    73081 atccattcgt gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc
    73141 aagagagaaa caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg
    73201 tgcgttgtcg ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga
    73261 aaggatcgga cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat
    73321 tggtgaaatc aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta
    73381 aagaatatcg tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg
    73441 gtgtcaaata tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac
    73501 aagtattgga agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta
    73561 tcaatttacg tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg
    73621 aagacatgat cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga
    73681 tcctgcctga aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt
    73741 atccagatga gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc
    73801 gtgggcaaaa attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc
    73861 agatcgcgcg acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg
    73921 ctattggaat cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg
    73981 caatcgaccg ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg
    74041 ctactcctcg tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg
    74101 ttttggttat catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag
    74161 cacggcgaga agttccagga agaagaggat atcctgggta tctttacacg aacttagcta
    74221 ctttattcga acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga
    74281 ttctaacaat gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta
    74341 cagaaggaca gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg
    74401 atgtactccc gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag
    74461 aagaccatgc agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa
    74521 aagaattagc cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga
    74581 agtttgctga gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga
    74641 ttactgaaac acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa
    74701 aacgaatcaa agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg
    74761 cacgattgaa tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa
    74821 ctgccacaag agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca
    74881 tcctgttgat tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag
    74941 caatgtctga ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat
    75001 ttgttttgcc ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa
    75061 aagtacctgt gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg
    75121 ggtatttgaa ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc
    75181 caaaactttt ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg
    75241 aaaagacacg tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa
    75301 cgatctatta tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga
    75361 tcaaagtaaa aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac
    75421 gatgattaaa caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt
    75481 aggatttttt ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa
    75541 tagtgggcat gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt
    75601 aacgggattg acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat
    75661 catgcttttg attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc
    75721 attgataaag aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct
    75781 agaagaagta tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgtgat
    75841 ccaattgatt ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa
    75901 aggtatctgg tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt
    75961 gttaggagac agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc
    76021 tttgatcatt tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca
    76081 gaaaaagaag atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt
    76141 aggcggattc gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa
    76201 tatgtttcaa cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata
    76261 ttattcagtt gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat
    76321 gtacatcggc ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt
    76381 gttgctgatc cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg
    76441 taccatccga caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt
    76501 gtgtgtagtc gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat
    76561 cgaatatatt gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt
    76621 gacgccagac ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg
    76681 agttggtgta ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa
    76741 atacaaatat ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta
    76801 gtgatttagt aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc
    76861 aaaatgttcg tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt
    76921 tttattgaaa ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata
    76981 tttttttatt ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga
    77041 ggatagggaa attcgaacga atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg
    77101 ataaagtcgg ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg
    77161 atcaactgga agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag
    77221 agaatcaaaa agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt
    77281 tgcttcattt gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac
    77341 atttatatta aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata
    77401 agcaactcgc aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt
    77461 aggtaataaa ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga
    77521 atggatatca tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc
    77581 tcgtcttttg tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac
    77641 accatgaatc ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc
    77701 gtcaaaatca attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc
    77761 gtatgtatat cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat
    77821 agccaatcca ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc
    77881 ttgagttttt aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg
    77941 gtaattaagc aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac
    78001 gaatttatta cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac
    78061 ttcattggta gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc
    78121 aatattcgta tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt
    78181 aaaatttaaa tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg
    78241 taatttattc tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg
    78301 cttcaatttt tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg
    78361 cattttctcc actccttaaa attgtatacc atacaatttt accattgatt gtattgattt
    78421 tagaagttaa tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt
    78481 agtagcttct tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta
    78541 tgaaagtggt aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg
    78601 caaaaatatg tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa
    78661 agtcattacc gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat
    78721 tttcttgttt gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac
    78781 ctggattcga acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc
    78841 agaaacactt gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc
    78901 taccattcgt cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac
    78961 ttttatcgct aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt
    79021 agaagatgca gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt
    79081 tcttcaaaaa gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc
    79141 tgatacaaga gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta
    79201 ctcagctgcc ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga
    79261 ggaatcttgt attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa
    79321 aggagaatcg aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg
    79381 tgcagaatat atttataaca aattagagaa aggggcttta aaatgaactt agattattac
    79441 gtagttgatg catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta
    79501 gaagaatggc tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa
    79561 acagcattta cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga
    79621 gaaatcgatc tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac
    79681 aaaatacctg atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga
    79741 attaaagatt attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg
    79801 tctgaatatg aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta
    79861 tttttcgtat tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc
    79921 aaaaattttg aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt
    79981 gtttctagaa ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca
    80041 cattctaatc ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat
    80101 caaatgtcat caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata
    80161 ggaggaaaag cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa
    80221 ttaaaaataa attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac
    80281 gcaaactttt tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt
    80341 ttattcaatc aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata
    80401 accatcaggg tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc
    80461 agtaatctca agaccagcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc
    80521 tatagcgata tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt
    80581 caactctaat tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc
    80641 tggaaaatca cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga
    80701 tgcttcaaga tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct
    80761 tttcctttta ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca
    80821 tgagaaattt ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat
    80881 ggataaacca atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc
    80941 atatattgtc atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt
    81001 ttttcttcct ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga
    81061 gctgatagaa gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga
    81121 gtatttttac tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc
    81181 tgattcttgg aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag
    81241 ccctcaagaa gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg
    81301 gatcgaaaaa aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta
    81361 tttattacag tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag
    81421 tgatgacatt tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac
    81481 cagcatattc aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt
    81541 gatcaatacc aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat
    81601 ttagtacttc gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt
    81661 gcggtaaacg cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga
    81721 cgatgttcat gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta
    81781 aacttgcttc gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt
    81841 catcgatcga atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat
    81901 cttcatgtgt cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg
    81961 ccccgttata agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt
    82021 cctggacacc tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag
    82081 cagcggcaat cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac
    82141 catcgatgtc gatagcgact agtttgatag acataatttc ctccaatata ttttaattta
    82201 tttcaatcaa tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata
    82261 aatcataatg atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat
    82321 ctccttgttc ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca
    82381 aagttccgtc atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat
    82441 aaaaatcata aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc
    82501 cgaccttttc tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa
    82561 aagtagcaga tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag
    82621 gatcagcaga ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga
    82681 ggtattcttc taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt
    82741 caaaactgct ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa
    82801 ttacttccat accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc
    82861 taacgatata atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat
    82921 aaggacgaat cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga
    82981 aataagcatc ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt
    83041 ggacaacttg tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac
    83101 cttcttctac tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta
    83161 cagtgatggc ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat
    83221 gaccgacatc atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc
    83281 ctccgttgcc tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg
    83341 aaatctcata aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga
    83401 aagaagaagt gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca
    83461 aatctaagat tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt
    83521 tttccatagg cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta
    83581 ttacgttgtt ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt
    83641 agccagtcgg tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca
    83701 aatgcttctt tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc
    83761 attgtagcag gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat
    83821 tgataaaatc gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac
    83881 atcataacag aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca
    83941 tggatgctta aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc
    84001 ggtgcctttg gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg
    84061 gttatttttt ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct
    84121 gatacgatcc ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt
    84181 gtttggatcc cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg
    84241 cagtcatatt gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat
    84301 atatctgtta atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga
    84361 atcgcagggt tcattcaacc ggctcctttg tataaattca tattttctac aatattatac
    84421 tctaaaatca aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg
    84481 acaaaacaaa agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg
    84541 aattatcaca aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg
    84601 aagtgcaaga tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt
    84661 acatacgtta taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat
    84721 tagttccaga tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat
    84781 ttggctataa agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg
    84841 ctacttttac gaaagaactg catgttagtt tgaaagaccg tcccacagca gggaaggttc
    84901 gaatcgatta tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg
    84961 attttacagc gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa
    85021 ggagtagact gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca
    85081 aaagcgaatt atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca
    85141 tggatttttc tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa
    85201 ttcgtgattc actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat
    85261 taggggataa tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag
    85321 taaaccatgg aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag
    85381 tcaacgcctt tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag
    85441 atacagatct gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg
    85501 aagaaatcgc tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg
    85561 atgaagaaga cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg
    85621 atgatgaaga ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt
    85681 cttacgagag gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt
    85741 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
    85801 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
    85861 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
    85921 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
    85981 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
    86041 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
    86101 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
    86161 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
    86221 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
    86281 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
    86341 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
    86401 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
    86461 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
    86521 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
    86581 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
    86641 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
    86701 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
    86761 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
    86821 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
    86881 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
    86941 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
    87001 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
    87061 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
    87121 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
    87181 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
    87241 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
    87301 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
    87361 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
    87421 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
    87481 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
    87541 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
    87601 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
    87661 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
    87721 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
    87781 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
    87841 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
    87901 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
    87961 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
    88021 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
    88081 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
    88141 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
    88201 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
    88261 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
    88321 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
    88381 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
    88441 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
    88501 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
    88561 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
    88621 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
    88681 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
    88741 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
    88801 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
    88861 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
    88921 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
    88981 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
    89041 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
    89101 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
    89161 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
    89221 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
    89281 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
    89341 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
    89401 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
    89461 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
    89521 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
    89581 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
    89641 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
    89701 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
    89761 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
    89821 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
    89881 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
    89941 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
    90001 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
    90061 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
    90121 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
    90181 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
    90241 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
    90301 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
    90361 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
    90421 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
    90481 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
    90541 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
    90601 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
    90661 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
    90721 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
    90781 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
    90841 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
    90901 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
    90961 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
    91021 atggcaatcg cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca
    91081 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
    91141 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
    91201 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
    91261 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
    91321 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
    91381 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
    91441 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
    91501 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
    91561 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
    91621 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
    91681 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
    91741 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
    91801 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
    91861 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
    91921 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
    91981 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
    92041 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
    92101 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
    92161 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
    92221 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
    92281 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
    92341 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
    92401 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
    92461 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
    92521 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
    92581 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
    92641 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
    92701 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
    92761 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
    92821 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
    92881 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
    92941 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
    93001 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
    93061 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
    93121 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
    93181 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
    93241 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
    93301 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
    93361 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
    93421 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
    93481 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg
    93541 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
    93601 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
    93661 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
    93721 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
    93781 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
    93841 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
    93901 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
    93961 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
    94021 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg
    94081 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
    94141 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
    94201 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
    94261 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
    94321 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
    94381 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
    94441 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
    94501 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
    94561 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
    94621 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
    94681 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
    94741 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
    94801 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
    94861 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
    94921 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
    94981 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
    95041 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
    95101 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
    95161 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
    95221 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
    95281 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
    95341 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
    95401 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
    95461 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
    95521 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
    95581 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
    95641 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
    95701 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    95761 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    95821 ttagttaagt aatcgaactc tctacttgct gaaatatcag caggtagaga gtttttttgc
    95881 aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca tccttgaaaa
    95941 aggaaagcta acaataacta gcatcatata agagctttta aggatagaac agtagaatag
    96001 gaatctatga gcaagtcctc tcgtataaat aaaataggag ggaagtagca gcatattttt
    96061 cataaagtgg ctctctttct tcatttttac tttggttgct cctatttgaa aattcgagca
    96121 cactcaaata caataaaaag aaatggcaag ggagaggatt agatgaaaaa agaagaaaaa
    96181 atcgcgattt tacaagagat catccgaatt aaatcagtga atggaaacga aggtgaagta
    96241 gcagcctatt tgaataagct tttggcaaag catgacataa caggagagat tgtttcttac
    96301 agagatggta gagataattt gattgctcgt taccaaaagg gccaatcagg aaaagtgtta
    96361 ggcctatctg ggcatatgga tgtcgtggcg gctggtgatg aatcgtcttg gacctatgca
    96421 ccctttgcag cagaaatcca tgggaaccgt ttgtacggac gtggtgctac agatatgaag
    96481 agtggcttgg cagcaatggt gattgccatg atcgaactga aagagtcagg aaaaccattt
    96541 aacggaacag tcaaattatt agccactgtc ggagaagaag tgggtgaact aggtggggaa
    96601 cagctcacga aagcaggcta tgtagatgac ttagatgcct tgatcatcgg agagccaacc
    96661 aattacagtt tgatgtatac gcacatggga tcaatcaact atacagtcac ctcgcacgga
    96721 aaagaagcgc atagctctat gccagaccaa ggttataatg caatcaatca cctaaatgaa
    96781 ttcattacga aagcaaatgc tgaaatgaat cacctcgctg aaacaatcga gaatcctgtc
    96841 ctaggaaaaa caatccataa tgttacattg atcagtggcg ggaatcaagt caacagcatc
    96901 ccaagccatg cgcagctcca agggaacatt cgatcgattc cagaataccc aaatgataaa
    96961 atcattgcat tgctgcaatc aatcgtcaat gaattgaatc aagagacaga ctatcatttg
    97021 gaattgatga tcgattacaa caaaatacct gtcaaagctg atccagattc tcctttgatt
    97081 cattgcattc agcaacaatt cagccagcca ttacctttag ttggagcggc agcaacaacg
    97141 gatgcagccg aatttacgaa agctaaccat tccttcgact ttgtcgtctt tgggcctggt
    97201 gtcgttactt tgcctcatca agtagatgag tatgttgaaa tcgataatta tttggatatg
    97261 atcgaaaaat atcaaggaat tattttatcc tacttagcgt aagatttttt taataaatga
    97321 aaaaacagag ccagattagc attatt
//
LOCUS       DAFLWZ010000003        72879 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000003 DAFLWZ010000000
VERSION     DAFLWZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.003"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(244..708)
                     /locus_tag="L1V38_000192"
     CDS             complement(244..708)
                     /locus_tag="L1V38_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1314774.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(730..1050)
                     /locus_tag="L1V38_000193"
     CDS             complement(730..1050)
                     /locus_tag="L1V38_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1314775.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(1194..2273)
                     /gene="pepA"
                     /locus_tag="L1V38_000194"
     CDS             complement(1194..2273)
                     /gene="pepA"
                     /locus_tag="L1V38_000194"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBN1314776.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            2473..2823
                     /locus_tag="L1V38_000195"
     CDS             2473..2823
                     /locus_tag="L1V38_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1314777.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            3046..3993
                     /locus_tag="L1V38_000196"
     CDS             3046..3993
                     /locus_tag="L1V38_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1314778.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(4050..5468)
                     /gene="pepV"
                     /locus_tag="L1V38_000197"
     CDS             complement(4050..5468)
                     /gene="pepV"
                     /locus_tag="L1V38_000197"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBN1314779.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            5617..6462
                     /locus_tag="L1V38_000198"
     CDS             5617..6462
                     /locus_tag="L1V38_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBN1314780.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6466..6906
                     /locus_tag="L1V38_000199"
     CDS             6466..6906
                     /locus_tag="L1V38_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBN1314781.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            6956..7150
                     /locus_tag="L1V38_000200"
     CDS             6956..7150
                     /locus_tag="L1V38_000200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314782.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            7286..7963
                     /locus_tag="L1V38_000201"
     CDS             7286..7963
                     /locus_tag="L1V38_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1314783.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(8371..9060)
                     /locus_tag="L1V38_000202"
     CDS             complement(8371..9060)
                     /locus_tag="L1V38_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314784.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(9035..11164)
                     /locus_tag="L1V38_000203"
     CDS             complement(9035..11164)
                     /locus_tag="L1V38_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBN1314785.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(11212..12549)
                     /locus_tag="L1V38_000204"
     CDS             complement(11212..12549)
                     /locus_tag="L1V38_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBN1314786.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(12801..13160)
                     /gene="rplT"
                     /locus_tag="L1V38_000205"
     CDS             complement(12801..13160)
                     /gene="rplT"
                     /locus_tag="L1V38_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBN1314787.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(13213..13413)
                     /gene="rpmI"
                     /locus_tag="L1V38_000206"
     CDS             complement(13213..13413)
                     /gene="rpmI"
                     /locus_tag="L1V38_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBN1314788.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(13485..14009)
                     /gene="infC"
                     /locus_tag="L1V38_000207"
     CDS             complement(13485..14009)
                     /gene="infC"
                     /locus_tag="L1V38_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBN1314789.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(14053..14178)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14329..14961
                     /locus_tag="L1V38_000208"
     CDS             14329..14961
                     /locus_tag="L1V38_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1314790.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(14963..15868)
                     /locus_tag="L1V38_000209"
     CDS             complement(14963..15868)
                     /locus_tag="L1V38_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1314791.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(15953..16612)
                     /locus_tag="L1V38_000210"
     CDS             complement(15953..16612)
                     /locus_tag="L1V38_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1314792.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            16928..17872
                     /gene="mvk"
                     /locus_tag="L1V38_000211"
     CDS             16928..17872
                     /gene="mvk"
                     /locus_tag="L1V38_000211"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBN1314793.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            17865..18842
                     /gene="mvaD"
                     /locus_tag="L1V38_000212"
     CDS             17865..18842
                     /gene="mvaD"
                     /locus_tag="L1V38_000212"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBN1314794.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            18855..19940
                     /locus_tag="L1V38_000213"
     CDS             18855..19940
                     /locus_tag="L1V38_000213"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBN1314795.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            19937..21001
                     /locus_tag="L1V38_000214"
     CDS             19937..21001
                     /locus_tag="L1V38_000214"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBN1314796.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(21250..22053)
                     /locus_tag="L1V38_000215"
     CDS             complement(21250..22053)
                     /locus_tag="L1V38_000215"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBN1314797.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(22073..22915)
                     /gene="kduI"
                     /locus_tag="L1V38_000216"
     CDS             complement(22073..22915)
                     /gene="kduI"
                     /locus_tag="L1V38_000216"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBN1314798.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(22931..23938)
                     /locus_tag="L1V38_000217"
     CDS             complement(22931..23938)
                     /locus_tag="L1V38_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBN1314799.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(23945..24589)
                     /locus_tag="L1V38_000218"
     CDS             complement(23945..24589)
                     /locus_tag="L1V38_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBN1314800.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(24689..25447)
                     /locus_tag="L1V38_000219"
     CDS             complement(24689..25447)
                     /locus_tag="L1V38_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBN1314801.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(25574..26725)
                     /gene="fucO"
                     /locus_tag="L1V38_000220"
     CDS             complement(25574..26725)
                     /gene="fucO"
                     /locus_tag="L1V38_000220"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBN1314802.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(26807..27118)
                     /gene="rhaM"
                     /locus_tag="L1V38_000221"
     CDS             complement(26807..27118)
                     /gene="rhaM"
                     /locus_tag="L1V38_000221"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBN1314803.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(27120..27965)
                     /gene="rhaD"
                     /locus_tag="L1V38_000222"
     CDS             complement(27120..27965)
                     /gene="rhaD"
                     /locus_tag="L1V38_000222"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBN1314804.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(27979..29235)
                     /gene="rhaA"
                     /locus_tag="L1V38_000223"
     CDS             complement(27979..29235)
                     /gene="rhaA"
                     /locus_tag="L1V38_000223"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBN1314805.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(29232..30692)
                     /gene="rhaB"
                     /locus_tag="L1V38_000224"
     CDS             complement(29232..30692)
                     /gene="rhaB"
                     /locus_tag="L1V38_000224"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBN1314806.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            30845..31714
                     /locus_tag="L1V38_000225"
     CDS             30845..31714
                     /locus_tag="L1V38_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBN1314807.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(31840..32739)
                     /locus_tag="L1V38_000226"
     CDS             complement(31840..32739)
                     /locus_tag="L1V38_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1314808.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(32904..33728)
                     /locus_tag="L1V38_000227"
     CDS             complement(32904..33728)
                     /locus_tag="L1V38_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1314809.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(33739..35034)
                     /locus_tag="L1V38_000228"
     CDS             complement(33739..35034)
                     /locus_tag="L1V38_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBN1314810.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(35050..35529)
                     /locus_tag="L1V38_000229"
     CDS             complement(35050..35529)
                     /locus_tag="L1V38_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBN1314811.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(35535..36563)
                     /locus_tag="L1V38_000230"
     CDS             complement(35535..36563)
                     /locus_tag="L1V38_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBN1314812.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(36580..37686)
                     /locus_tag="L1V38_000231"
     CDS             complement(36580..37686)
                     /locus_tag="L1V38_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1314813.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(37915..40512)
                     /gene="adhE"
                     /locus_tag="L1V38_000232"
                     /gene_synonym="adhC"
     CDS             complement(37915..40512)
                     /gene="adhE"
                     /locus_tag="L1V38_000232"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBN1314814.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(40817..41197)
                     /gene="yajC"
                     /locus_tag="L1V38_000233"
     CDS             complement(40817..41197)
                     /gene="yajC"
                     /locus_tag="L1V38_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBN1314815.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(41294..42439)
                     /gene="tgt"
                     /locus_tag="L1V38_000234"
     CDS             complement(41294..42439)
                     /gene="tgt"
                     /locus_tag="L1V38_000234"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBN1314816.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            42657..43355
                     /locus_tag="L1V38_000235"
     CDS             42657..43355
                     /locus_tag="L1V38_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1314817.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(43523..46162)
                     /locus_tag="L1V38_000236"
     CDS             complement(43523..46162)
                     /locus_tag="L1V38_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1314818.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(46781..47812)
                     /gene="queA"
                     /locus_tag="L1V38_000237"
     CDS             complement(46781..47812)
                     /gene="queA"
                     /locus_tag="L1V38_000237"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBN1314819.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            48005..49180
                     /locus_tag="L1V38_000238"
     CDS             48005..49180
                     /locus_tag="L1V38_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1314820.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            49184..49825
                     /locus_tag="L1V38_000239"
     CDS             49184..49825
                     /locus_tag="L1V38_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314821.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            49822..50739
                     /locus_tag="L1V38_000240"
     CDS             49822..50739
                     /locus_tag="L1V38_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1314822.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            50736..51407
                     /locus_tag="L1V38_000241"
     CDS             50736..51407
                     /locus_tag="L1V38_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314823.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(51948..52436)
                     /locus_tag="L1V38_000242"
     CDS             complement(51948..52436)
                     /locus_tag="L1V38_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBN1314824.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(52637..52903)
                     /locus_tag="L1V38_000243"
     CDS             complement(52637..52903)
                     /locus_tag="L1V38_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1314825.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(52903..53166)
                     /locus_tag="L1V38_000244"
     CDS             complement(52903..53166)
                     /locus_tag="L1V38_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1314826.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            53642..53827
                     /locus_tag="L1V38_000245"
     CDS             53642..53827
                     /locus_tag="L1V38_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1314827.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(53969..55792)
                     /locus_tag="L1V38_000246"
     CDS             complement(53969..55792)
                     /locus_tag="L1V38_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBN1314828.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(56390..59095)
                     /locus_tag="L1V38_000247"
     CDS             complement(56390..59095)
                     /locus_tag="L1V38_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBN1314829.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(59401..60348)
                     /locus_tag="L1V38_000248"
     CDS             complement(59401..60348)
                     /locus_tag="L1V38_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBN1314830.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            60538..60807
                     /gene="rpsN"
                     /locus_tag="L1V38_000249"
     CDS             60538..60807
                     /gene="rpsN"
                     /locus_tag="L1V38_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1314831.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(60983..61345)
                     /locus_tag="L1V38_000250"
     CDS             complement(60983..61345)
                     /locus_tag="L1V38_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1314832.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(61356..62477)
                     /locus_tag="L1V38_000251"
     CDS             complement(61356..62477)
                     /locus_tag="L1V38_000251"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBN1314833.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(62493..62843)
                     /locus_tag="L1V38_000252"
     CDS             complement(62493..62843)
                     /locus_tag="L1V38_000252"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBN1314834.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(62973..64484)
                     /locus_tag="L1V38_000253"
     CDS             complement(62973..64484)
                     /locus_tag="L1V38_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1314835.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(64806..66158)
                     /locus_tag="L1V38_000254"
     CDS             complement(64806..66158)
                     /locus_tag="L1V38_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBN1314836.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(66311..67387)
                     /locus_tag="L1V38_000255"
     CDS             complement(66311..67387)
                     /locus_tag="L1V38_000255"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBN1314837.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            67583..69328
                     /locus_tag="L1V38_000256"
     CDS             67583..69328
                     /locus_tag="L1V38_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBN1314838.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(69608..70045)
                     /locus_tag="L1V38_000257"
     CDS             complement(69608..70045)
                     /locus_tag="L1V38_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBN1314839.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(70029..71402)
                     /locus_tag="L1V38_000258"
     CDS             complement(70029..71402)
                     /locus_tag="L1V38_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314840.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(71724..72212)
                     /locus_tag="L1V38_000259"
     CDS             complement(71724..72212)
                     /locus_tag="L1V38_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1314841.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(72234..72836)
                     /locus_tag="L1V38_000260"
     CDS             complement(72234..72836)
                     /locus_tag="L1V38_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1314842.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        20853 a        15643 c        13333 g        23050 t
ORIGIN      
        1 caacttttac aatttcaaac tacgaattat gattcgtcat ggcaaaacat ttttaaccaa
       61 ataaacagaa cagaaagagg ttttcttctt tctgttctgt ccaaattatt ctaagatttc
      121 tctttaccaa catcatttga caaagagcct ttattcgtaa caagggactg tgacaagact
      181 tttgtcacag tccctttact gttttagtta attgattaaa aaggtcgtac aagttccact
      241 tgcttaatta cttggctgtt cttcttcgtc agaaacgatc aagacatcac aaggtgaatg
      301 acgtatcacg tagctggcta cacttcctgt cataaagcgt tcgactgcat ttagacctga
      361 ctgcccaacc atgattagat cgatctcata tttttttggc aatttgactg ccatggattc
      421 acgaacagaa ccatatgcaa taattccttc tatatttgtg taatcaacag atttcccata
      481 ttctttacat tcttcgatca tttccttggc tgtttcagtt tgctgatcga ctagattttg
      541 atcaataggt gcatagccca taaagttata aaattgctga tcgattacgt ttgctacata
      601 tactttccca ttattacggc gagccacttc taccgctttt ttgaaagcag caagtgcttg
      661 ttcactaccg tcgataccta ctaaaatatt cttatattct tgattcatct tgacccctcc
      721 taacagatgt cagccttttg ttacactttc taggaacgat tcgatttcct gttttgtttt
      781 acgatcttta ttcactagac gacctaattc ttttccgtct tggatcacga caaaacttgg
      841 gataccaaaa atgttccatt cagcggctac atctatgtac ttgtcacggt ctacttcaat
      901 aaattgccaa tcagaaaagt cattttcaat ttcaggcatt tgcggtttga taaaacggca
      961 gtctccgcac cagccggcag taaagaaaaa tacactcttt ccagtttcta cgtagcctgc
     1021 taattcttct aaactatttg ggataatcat tctttgtcct ctactttctg tttatgtatt
     1081 tttcaattaa attatacacc tttctttcga actaacaaac attgatcctc tttttataaa
     1141 aaaaatctgg caaaaagcaa tcttttgcca gattttatag tttcactatc gcattatttt
     1201 ccgtatacga tcgtatttac tgttgattta tccaaacctt tcagtgtttg aatcaacatt
     1261 tctcgtgcag cttcaaaatc gcgaatactg aacatcgttt gatgcgtatg gatataacgt
     1321 cccactacgc caatcactgt acttgggatt ccttcgtttt gtgtatgagc agcacctgca
     1381 tctgtaccgc cttttgaaac aaagtattga taagggatat tgtttgtttc agcgatatcc
     1441 agcaagtact cgcgcaaacg aggaagcatg atcaaacctg gatcttggat acgcatcaat
     1501 gtaccttctc ctaaatgtcc gaatgtgcca tttttcgtca ctgtatcatc tgctgcagag
     1561 cagtctactg caaagaacag atctggcttg aatttattga cagaagcttt agaaccacgc
     1621 aagcctactt cttcctggac attcgcgcct gcaatcaatg tatgacctaa tgtttcattt
     1681 tgcaacgctt ctaaagcttc taataccatt gtacagccat agcggttgtc ccatgattta
     1741 ctgataatat tctttccgtt ggctgttttg atcgtttcag cgtaaggaac gattgtgtct
     1801 cctggaagga caccgtaact cattgcctct tctcttgatt caaacccagc atcgaacaaa
     1861 atatcggtta cttctactga tttttgtccg cttgttcctc gcaataaatg tgggggaacg
     1921 gaagaagaaa tacatggata attcttacca gtagaggttt taagtgtaaa acgctgagca
     1981 gaaacaacgt aaggattcca gccgcctaga ggtacgactt taaaaagccc gttttcttgg
     2041 atttgtgtca gcatgaatcc gacttcatcc atatgtgctg cgaccattac acggggtgca
     2101 tccgcttctt catgatggcg cagaccaaaa atgccgccca aaccatctaa ctgtaactca
     2161 tctaccagcg gttccatatg actttccata taagcgcgaa catcttgttc aaaaccgctt
     2221 gttccttgta attctgttaa ctctttgatt cgttgaaatg ttttttcttc catatgctat
     2281 tcgtctaaat ttcagactaa actcctctca gacttatatt gatctgcgga taaaatatga
     2341 ttttttctgc agaccgatcg tatttattat agcttatttt ttctggtagc ggttatttat
     2401 ttcaaagaaa atatgagagt gtggtaaaat aagcacaagg agtaacaagt gagaagaagg
     2461 aggtatgtcc acatgtatga agaaagcgaa ctaagctatt ttaaaggcgg gttagcagtt
     2521 ggaatcggtc taggattatt gagcggggta gcttcaacga tttggtatca tcgcaaaaaa
     2581 gtattgtcag cagaccaagt acttgaaaat atcaagtcat cttttctaaa agaaggtgca
     2641 atcgaaggtt cttggatctc ttttgaaaag gaacctatta ggaaattcgc cgttcggtcg
     2701 agtgcttatc ggggaggtct ttctcgaata gaagatggcg aaactgttta ttatgaattt
     2761 ttagcagatg ctcatacagg aaccgtatta gaaatttcaa gaaaaaaagg tgcaacagat
     2821 taatacgtca aaaaagtgag agaacgaata cgcacccact attcaaaaga gaggtatcat
     2881 gtccttcttt tgtagtgggt ggttttttag atagagcttt ccaaacatat attccagtat
     2941 tttcttttta aataaatgat atttagcggg aaaaactagc atttcctttg attatgaggt
     3001 atttttaatt tagcttttgt tttctatagt taaggagagt gaaaaatgga acaacaagaa
     3061 aaaattgctg ttctgattcc ttgttacaat gaggaagcaa caatttcaac agtcattgca
     3121 gactttaaac gagaattacc agaagcagat atttatgtct atgataataa ttcgaccgat
     3181 cgaacatacg aattggccgt tcaaggtgga gcaatcgtaa aaaaagaacc tcgtcaagga
     3241 aaaggaaatg tgatccgcca aatgttcttt gatatcgatg ccgactatta tttaatggta
     3301 gatggcgatg atacttatcc tgcagaagct gtacatggtt tgctcgagaa attacgttct
     3361 ggtgaagcag atatggtcat tggtgatcgc ctatcaaatg gaacctactt tgatgagaat
     3421 aagagacctt tccacgattt tggaaataac cttgttagaa atacaattac tagaatgtat
     3481 aaaacaaaaa ttcttgatgt catgaccggc tatcgaggat tcaatcgtat ctttgtcaaa
     3541 agttttccta ttatgagttc tggttttcaa atcgaaacgg aattgacgat ccatgcttta
     3601 gataaaaaat tcaagttcgt tgaaatccca atcgattatc gtgatcgtcc tgaaggcagc
     3661 gaatcaaaat tgaatacatt ctctgacgga ttcaaagtga tcatgatgat tattaaaatg
     3721 tttaaagatt ataagccttt gcttttcttt gggatttgga ccatcttctt ctttttattt
     3781 ggattggtca cggggattcc tgtgattcgc gaatatatgc tgacaagctt tattacacgc
     3841 atcccttctg cgattttaag tactggattg atgactttag cacttctttc attagtaaca
     3901 gggttgattt tggatacagt cgtcacgaac gctaagaaag aatatgaatt gaatctatat
     3961 catgtttatc atgaatacca cagtagaaag taaaaaaagg atcaagactg caaaaataat
     4021 ttgcaattct tgatcctctt tttaattaat tatttcgcca aacgatagat ggcatctgca
     4081 tagattgctg ttgctctgaa caagtcatca agactcataa attcgtttgc ttgatgcatt
     4141 gtatcagtat atcctgggaa catcgctcca taagcaacgc cacgtttcaa caaacgtccg
     4201 taagttccgc caccgatgat ttgttcgtag cctttttctc cagtgtggtc ttcatagact
     4261 tgcaataatg tagccaccaa tggatcatcc attggtacgt aatgtggttc cattacgcga
     4321 gcacctcgag taactgttgc gccttcttgc cccactgttt gttcgatgtc actttgcaat
     4381 ccgtctactg ttacaccttt tggaaaacgg aaattcatat tgatgaagtt cgcttcctct
     4441 gtaccatttt cttcaaaagc aaatagtcca gcattcattg tcaatttgcc cattttttca
     4501 tcttcataag cgactcctag tttttctcca taaaaatctt catggacata agcagctgct
     4561 acatggataa attgtttagc agatcctagg aattcatagt tatctaagaa caatgccaag
     4621 aaagaacctg cattgatacc agattgtggg cttgcaccat gtgcgccttt accaactaat
     4681 tcgattttta catacgtatt gtccgcttca atcgttccgc ttactggatt tgcttcgatg
     4741 aattggtaaa atgcttcttc catcgcgata gctgcatctg cacttggtac ttgaagtgct
     4801 gcagttgctg ttcctggcac catattttcg cgaagtccgg aaacaaaaga tttcaagaca
     4861 taatctcctg cattgtcgcc tttgaagcgt aaagctaaag aaacatttcc tttttcacca
     4921 ttgatgattg ggaattcagc atctggtgag aaaccaaaat ctggttcttc ttcatgttcg
     4981 aaataataag ccatatcgcc ccagccgctt tcttcatcgc tgccgactac gaagcgaact
     5041 ttttttgata gtttcaagtc aagttcttta atgatcttca tcgcatagta agctgccata
     5101 cttggacctt tgtcatcgct tgatccgcgt gcaaagatct ttccatcctt gattactggt
     5161 tcataaggat ctgtgtccca gccatctcct gcaggaacga catccatgtg tccaaatatc
     5221 cctagcgttt cgtctccttc gccaagatca atatgccctg catagttatc gacatttttt
     5281 actttaaatc catcacgttc gccataagct aacatatgtt tcaatgcgtc gcgaggtcca
     5341 ggtccaaatg gtgcatctgg tgttactttt gagtcatcgc gctcgctgtt gacacgtaaa
     5401 agatttttca agtcttcaag caagtcttct ttacgtgctt ctacttcttt ttgccaatca
     5461 attgtcataa agttaatcct ccacttattt aagtcttcgt gttcatgata ccacaaatta
     5521 cagaaaaaaa tagttcaaaa aatctgacaa ttccttttct tatctgtttt tctctaaaaa
     5581 aaatatacgc tataatgagt aaaaggaggt ttttagatgc tgataaacga acaactagtg
     5641 aaaagagtca tcacacctcg tccaaaaatt tcacataaag gaacatttgg acgtatcgtt
     5701 ttgattggcg gcaatgaaca atatggcgga gcaatcatta tgagtgcttt agctgccgta
     5761 cacagcggag cgggtctcac gactgtagta actgatgaaa aaaatcggag tgctcttcac
     5821 agtcatctgc cagaagcaat gattgtagtt tggacggata ctgaccagtt tctttccgta
     5881 ataaagcaag cagatgtact cttgattggt cccggattgg gtacttcttc taagagtttg
     5941 gaacgtttca aacaagtact agaaaaccaa tcaaaagaac aatggctggt gattgatggc
     6001 tctgctttaa gtttacttgc tgctaatcat cttttgctac cctatcccga acaaactgta
     6061 cttacacctc atcaaatgga gtggcaacgg ttgagttctc taccgataca agaacaacgg
     6121 gataaagaaa acaaaaagaa gcaacaggaa atcggtgctg tgctcgtttt gaaaagtcat
     6181 gagacaaaaa tttatggtca ccagcacttc tacaccaatc ctttaggttc tgctgctatg
     6241 gcaacgggcg gcatgggtga cactttagct gggatgatca caggattttt agcccagttt
     6301 cctcaaaatg accaaacgat tgcagcagct atttatcttc atagtttcat tggagaccag
     6361 ctggcaaaag aacaatatat tgttttgccg acacaaatca gcgaagcact tccgaaatgg
     6421 atgaattatt tttgtaaaaa atcaatggaa aacgaggcat gagtcatgga gaaatttaca
     6481 ggttatgtgc gagaaccttt ttattatgaa acagatcaaa tggggattat tcatcacagc
     6541 aattatatcc gctggtttga agaggctcgg gtagccttat tggtacatct agggtttccc
     6601 tataaaaaaa tcgaagaatc tgggatcatc atccccgttc tggaagtaaa ttgcagctat
     6661 aaagaaatga tccattacgg agaaaaagtg agcatccatc caactatcca aaagtatacg
     6721 gggacacggt tggattttag ctacgaaatt gtgggaactg aagacaaaaa attaaaaact
     6781 actggcagta gtaaacactg ttttttactt tctgattcgc aacgattagt gaagctgagc
     6841 aaagtcaatc cggagttaga tcagttattc caagcgtacg cttctttgga tgatgtaaat
     6901 tcttaataaa gaccgtctaa gcatttttct tgtattgtgt cgagtagttc gtataatgaa
     6961 aagaaaaaag caggtgatcc ccatgtatgt cgttaaagta atgcacggtt acatcgataa
     7021 aactggctgt cgcactcggg aaaaaaactt agacaatctg ctcattttca aagacaaaaa
     7081 agaatccgaa gcttttgcta aaagaatcgg cggtcgtgtc aaaccgatcc aagaggtacg
     7141 accagattga ttcaatattt ttcttttcga ggctctaata ggcatgccta tcagggcttt
     7201 ttttgcagac tgtgttttta tgcccacacg atttgtaagc gatttatgtt ataatagatt
     7261 atatctgcat agaaaggaag gttaaatggt tatcaataat ttgcaacagc aagcttatga
     7321 atctatacgt aaacaaatca tttattccga gttagcacct ggaagtaaaa tctccgataa
     7381 agtgttagaa gaacaactag ctatcgggcg tacaccgatt cgagaagcac tgatccaact
     7441 gcgcaatcaa gagcttgtaa aaaccattcc acagtccggc acttatgttt caaaaatcga
     7501 tatccgatct gcttcattag cccgttatac gcgggaaaag ttggaaaaac cgatcctgca
     7561 agaatgcagt gcgaaaatga ccaagcaaga tcaagctaaa ctagaaaaaa tactagaaca
     7621 aaccgatcag gcagtaatcg ctcaaaataa aaaagctttt tttgatttgg atactgattt
     7681 tcaccgaact tgttatgaaa ttgctggaaa acgagaaatt tgggattggc tagaaagtta
     7741 tagtacgcgt ttcagatggt tacgtttgac gatttcagaa ttagactggg gtcgagtatt
     7801 agatgaacat cagacaatgc ttcaatcaat gattgatcat aactttgatg aagtcggatt
     7861 tctttgcacg atgcatttac atatgattat cgaggagcaa gaatacgtga ttcataatta
     7921 ccccgattat tttgaagata ttcaggacag acccatcaaa taagaggttt tggaatcagc
     7981 gttttgacct gagtattaga gaaagaaacg gcaaaatagt tcctcatatt ttgccgtttt
     8041 ttttgagcta ataccgaggg tcagctgatt gcacaccgtt tattgagagg ttgtgaaaaa
     8101 gctgccctgc atcaagtaat aagaacagcc aagtaaaaat agcttcttat gtttttaact
     8161 tggctggact tattaccgca gatgcaagct tttgaacacc gttttccaag aggtcgtgag
     8221 cctgccgttc atctccgagt cacaaggaac aatttcaaaa aacagcttct catgtttgtt
     8281 gaatattttg acttgtgacc gaggagttga caggagaaca tcgtttattc ggaaaaaaag
     8341 gactgtgaca cgacttttgt cacagtctct ttatttgtaa tctaaatcat actccgtaca
     8401 tcttttttct atttttttta tttcttctaa gatcccttgg ctacgaattt cattatatgg
     8461 ccaaagtaag actgcctcta atacataagg cgaaaaatcg ctttgattca tctcttttga
     8521 aaaactcatc gctgctatct cgctcaatgc acgaatgttt gattgatgtg tataaaaagg
     8581 caaccgccac agcacaattt tttcgctttg cgtataaatt cccttaacag aagcttcgat
     8641 gtggtgaaat agttcatgtc caataatcaa agcttgcgct gtttctttag agatcgaagc
     8701 tagtcctgaa cattttaatt tttctaacgg ctccgtcatc aatcgaatcc cttcatcttc
     8761 tgcataagtt gcaaaagtga ttcgttcgtt tatttgctct gattcacagg aaacgattgg
     8821 aacagccatt tgttcacaaa tttctcctac atcggcaaaa gggtactttt ttttgatgct
     8881 acatgccgtt tcgataccac aatcgattga ttgttgtata agaattttct gcttggacaa
     8941 aggaatcttt ttccaaaata aatctcgccg aaactggtag aatccccaaa tttcttcggg
     9001 gatctgttgt aattcgttta gtaactcttc taacttatgt ttgtttgata tttccggcaa
     9061 cgacgatcac ttcttcctcc ggttccatag tagatacttc cagatccatc aaaagctgta
     9121 gttgttccag atccgtcgct gtaaaatcag agactcttgc tcctaagcag agataaaatt
     9181 ctggtcgggc aatcaattca gtttgataaa ctgccatatc ttcccaaagt tgttcgacag
     9241 ctgtcatata attggctgca gttgttttca tacatgaagc atgtccacgt tggaccttga
     9301 taaatccttt ttgatcgatg atccgaagac ttccagcatt ttttgaacga ttctgttcgc
     9361 cgcatacata aaagaaaggt gtattttcca ataagcaaac ttcattttta tttaatcgca
     9421 tatcctctgc agcaagctct agtgcttctt ctgttgtgat ctccttggtt agatcggttg
     9481 ctttcacttc cgtagaacca gtagcgatag ccgttacttt tgaagtctgt ggatcgattt
     9541 ctacgtggac ttcgatcgat tctggtgtag cgcctgattc aatcgcttta ttcatcgctt
     9601 catttttcaa cgatcgtata tcttctttac ttggcgaagg gatgatacgt tctacaacat
     9661 ctcggaccat tgcaagtgct acaccaatag aagaaatcac ttcggcgttt tcaggaatcg
     9721 aatatttcac acccatttta ttactaaagt aagtaatcaa tgaggcagcg ccgcccccta
     9781 cacctacaag agaaatctga tctttctcca agtgatactt gtctgccaat tctaaaatca
     9841 ccggttcaat cttagcatag gatttttcca tgatctgttc tgcgatgtct tcaaccgtcg
     9901 tatgacaata atcagctaat gcttggatgg cttttcgtgc agatgggaca tttccataag
     9961 aaaaatgttc ttcttgcact aatccaagga cattggctgc acatgtattt gtaatagtca
    10021 cttcttctcc gtcttccatc actaccttga cgtaatcagc agggtctcct tctttaggag
    10081 agaaaaattc aaccttagga cctttgattt tttctgtctc cgtaaatact gcataatcta
    10141 gaccggcaat atgtgcagaa cgtggaccga catcgatgat tcctgactga ttagcccgta
    10201 ccatcgaacc gcctgccaca cctagaaccc gaacatctaa tgaagagata tatgttgggt
    10261 ggccacctac aattgaataa tcgattgctg gacgtccatt tttaatgacc ccgatattgg
    10321 ttgttgttcc gcctacttca aaataaacac cattagacgc tctcaagtac atcaaagagc
    10381 ccatgactga tgctgctgga ccggaaagca tggttaaaac aggtcgtttt ttcatttcat
    10441 tgatttccat tactccgccg tctccgcgca taatcatcaa agaaacattg acccctgctt
    10501 ctcgtacgga atcttctgta gaggttgccg tatctagcat ttttggtaaa atagatgcat
    10561 tgattgctgc tgtccgagtt cttcttgtca atccatataa ttttgtgatg tcagaagcca
    10621 tcgttgtagg gatcgatttt accgatgctg cttcataaac aactcgttct ggttccccat
    10681 tatctactcc aaatgccata gaagaaacca agacctccgc tctttctctt tctaaagaag
    10741 aaatcgtttc tgaaacacgg tctacattta agtgtttgac aggtaagaat gcattgacaa
    10801 tctctatttt tttcttattc cctaaatcga tatcgttcaa tctagtttgt cgttttgcta
    10861 aaaaaccttc taatccacct tttgccatcc cgattacgcc gacttttgct acgtctcctt
    10921 caatcagtgc attagtcgct tgtgtggtag aatgtgcaac aaacacaaca tcttctggac
    10981 tgatattatt ttccagcaaa caattttgaa aagactgaac gacacctgcg gctactccac
    11041 ggacatcatc gtgggttgtt ttcactgaag attttccgat gatttcgtgc gtcgcattat
    11101 cgattgcgac tgctttcgta tgtgtaccgc caacatcaat tcccattcgc acaaaacgtt
    11161 tcattttctt ttcctccatt catctaatcg tttttatcga cgttttgttt actaggcgtt
    11221 cccgtacaat aagaacgtga tcaggcataa gatcgctccg atgatccaac cagttgggat
    11281 ggatttcttc atatattctc gagaagttac ttttgtataa cctaatcccc aagcaaccca
    11341 agattgtgta atatctaaat gctgaggagc aatcgttgtg attgcaaata acgggaacaa
    11401 aaaggctggc gacatcgttg gattaacagc taatacgaca gctaaaatag ctgagcctga
    11461 accgactaga ttcattggac cgcggaaaaa tcctagtggt gtcaatatag caaatacgat
    11521 tgccaagact aatggtgatt gcggtatcca atctccaaaa atagctgaaa aataaggaga
    11581 agcatacgca gctgaattat tgaacatcgc taaggtcatc aagaaaccaa ccattggcgc
    11641 aacatctact gcgccatctg taaataattt cgcaaactga cgacagattt ctttataacc
    11701 tccgcgcaat tttccagtaa acagcaatgc ccagatacct gctagaataa aacctaagat
    11761 gattggaaga tctaaaagaa cgacccctaa aactggtaat aatacggcta accatgagat
    11821 cattggtgcg tcgccacctt cagctggtac gtttgctgcc attgcatagc gtttcttttt
    11881 gttcattgat atattagcga ccgttagtac cacaactaag cttacaatca tcccaatcat
    11941 accaatttgg aaatagtcat tataagtata gctttcagcc gctggattga aaccagcata
    12001 aatcgtttga tattgtttga aattgacgat attagcaaag attccagcca taatcgagcc
    12061 cataaatgag aacagtgcaa ccggtactga aatacctaat gacatcaaga ttggcaacac
    12121 aataactgca atagaaatca ctggtccgat tcctgtcatc gacatgaata taacagcggt
    12181 tacaatacat agtaagctca tcgtgattct tggcttgtcc cctccaagtt caactacctt
    12241 tcgaatcagg gtagctgcga ttccgctatc tactagaaca cgcccgaaaa aggcaccaaa
    12301 gaagacattt accaagatcg atttggcgta ctcagctggc cccgtcgtat agatatgcgt
    12361 caacacatca attactcctt gcccttccat cgccgggttt ggtgaaaacg tgtttccgac
    12421 tagcgctaat cccatccata cagtagccat gatggcaaag ccgaccatca agttgtagcc
    12481 ttttacacag taccagacca tgaaaaagaa tgagataact aacaaaatac caataataat
    12541 atcactcatg ttattcctcc gtccattttg tttttctgat aagcaaacta atatatcagt
    12601 caaactcatt ctaacttatg tagttagcgc tttcattaaa gggtgaccat aaatgttcag
    12661 ttttcaatta aaaaacctta attatgctat tttagactta tacgttattg tcctgtttca
    12721 tttgatggag gattgtaaat aaaaaaagag gaaagaacat aacttttcgt tatcttcttt
    12781 cctctttata attgtttagc ttatttagcc aaagcttctt ttgcttggtc agccaatgca
    12841 gtaaatgctg ctgcatcgtt aacagccaag tcagctaaca ttttacggtt gatgtcgatt
    12901 tcagcaactt tcaaaccgtg cattaatttt gagtagctca agccattcat acgagctgct
    12961 gcgttgatac gagcaatcca caatttacgg aagtcgcgtt tcttttgacg acgatcgcga
    13021 tatgcgtagt tgtatgaatt cattacttgt tcttttgctg ttttaaataa agtgtgtttt
    13081 gaaccgtagt aaccttttgc taattttagc actcttttac gacgtttacg agttactgtt
    13141 ccacctttaa cacgtgccat gtataattcc tcctaataaa aataaatctt cagattctgt
    13201 tatttgtact tcttatttca tttttgctag ttgttggcga atacgtttga agtcgccact
    13261 agaaaccatg cttgctttac gcaattgacg gcgttgtttt tttgttttgc cgtggaaacg
    13321 gtgacttgta aacgcgcgga agcgtttcaa tccgccttta ccagtacgtt tgaaacgttt
    13381 tgctgatccg cggtgtgttt tttgttttgg catgactata tttcctcctc aaaatctttc
    13441 gttatccgac tatcggctgt ccaacagcca gttagtcatt caaattactt actgtcgttt
    13501 ttcggtgcca gcgtcaagaa catgctgcgt ccgtccattt tcgctttttg ttccactgtt
    13561 gcaatatccg cagtttcttc agctaagcga ttcaagactt tttgaccaat ttctttatgg
    13621 gtaatggcac ggcctttgaa acggatagaa gctttcactt tatcgccctt ttccaagaac
    13681 ttacgtgcat tacgaagttt tgtattgaag tcattcaagt cgatcgtagg acttaagcga
    13741 acttctttta cattgatcac tttttgtttt ttacgcgctt cgcggtcttt cttttgttgt
    13801 tcgaaacggt atttaccgta gtccatgatt cgcgcaactg gtggtttcgc accaggggca
    13861 actaacacaa gatccaagtt tgcttgttct gcaatattca atgcttctgc ttttgtctta
    13921 actcctaatt gctcaccatc tgaaccgatc aatcgtaact ctcgtgcacg aatgccgtcg
    13981 ttaaccatca tatcctttgc tatggtcatt cacctccaaa tattatgaga gaaagaaaag
    14041 cttaccgaat aaacggcaat aaaaaaacga gttctcttac agaacccgcg cgtacttcac
    14101 ctaatagaac cagtgaaaac tatctagccc agtgacatta tcaactaagg cgagaagcgg
    14161 gtgcttctgc ttttatttct caaccatcat agtatagcaa aaactaatct ttttgtcaat
    14221 gtttttcata cagtttgtct tccttttctg aaaatgatta gattagcaga ctttctagca
    14281 gtgattcccg cttctttgct atactaaaga aaaacgaggt gaacccacat gaaaaaaatc
    14341 gaacctattc caccttctct tcctcttctt acaaagggag agttttattt agaagatgag
    14401 gagatcttct ctggtcttct gatcaacggg ggtgaccaaa gctatctcga tgccaaaaat
    14461 atggtattaa gagagagtca tatccaaaaa cttacgatgc aaaaaacagt tttacgtcat
    14521 tttgaatgca gtaatgtcat ttttgaaaaa tgtgattttt ccaatctgga gtggattggt
    14581 ggcagtttcc accaagtcgt gtttcatcaa tgtaaattaa caggtacgaa ttttgccgaa
    14641 agttatcttc gagactgtac tttcactgat tgtattgctt cgatggcttc ctttagtagt
    14701 acaaacttga aagctgtctc cttcgatcat tgtcaattag aagacagcga attttatgag
    14761 gtcacttgga aaaacctttt tttgtctgac aatcagttga ccggttcgaa ctggtttcga
    14821 acttctctga agggattaga ctttacgact aatttcttca cagcaatcgc tttatctcaa
    14881 gattctttgg cgggactaat cgtcaaccaa gagcaagcac ttgtgatcgc ccaagccctt
    14941 ggtttgcaga tcaaagacta gatcaacgaa tccgccgcca cagtgcaata agcatccaaa
    15001 tagataagac caaactgatg atcaaggcga ttccccatcc gaaaacggaa tgggtaaagg
    15061 gtaactggag attcattccg aagaatcctg tcacaatagt tggaacggtc aagatcagcg
    15121 accagaccgt caaaaatttc atcgtgtcat tcaagttgtt attcagcaaa ttattataag
    15181 tgccagagag ctggtctaaa atctgcgaag ctaagttcgt catttcaact gcttgtcgtg
    15241 cttcgatcag cgcatcgtcc aactcttctt tttccttttc tgacaacttg cgataaatag
    15301 ccaatgcctt gatttgttct aaaagtacta cattttgttt tgttcctgta actaagtaaa
    15361 ccaaaccgat ctctaaatct gaaagttgca gcagattctt gttcgttgtt ttttctctta
    15421 atttcagatt aagccgctga cgttcactat tcacttcctc gattaaagga aaaaaggaat
    15481 cagaaatcaa aaacaatgta cgaaacaata aactgtatac actcatgtct ggcattcgtt
    15541 ccaaaagcga tcgaattagt cgaatcacgt actcggtatt cggcgtggta aatgtaaaca
    15601 aaccgtcttc ttttaaaata aaagcgatag gactagtttc ataatgatta tcgacttttt
    15661 gctggtgcgg aacatttgat acaagcagta acgcttcatc aaaagaatcg tactctacgc
    15721 gcgcccgttc atttttatct agagaataag tcagcatctc gtcactaatg ccatattctt
    15781 cttttaagtt tttaacagct agcacatcgt tttgctgtac attgatccaa aaattacggt
    15841 cttgattaaa atagtgtttt tcccgcatac tctatcctcc tgacatttgt ttccagtata
    15901 aagaaaaaag tcgctcaaat aaaggtttac cctttatttg agcaactgta aatcaaatgg
    15961 ctactttggt ttggcgaatc tctgctaatt tttcttcgat cattttcaag acttcttctt
    16021 ttgcttgagg atcttccaca aaattatagc ggtctccatc gatttggatt tttggacttt
    16081 ctttgtattc ttcataccat tgatcgtaac gtctgttcaa ttctttgtaa taatcgtata
    16141 gacttggatc aaaggacaat tgttcatacg aacgaccacg tttttcgata cgctccaaca
    16201 tcgtatcaaa agatacacga atatgaacta ataaatccgg atgtttttta tgggcagcat
    16261 agggaagttc ttccatcatg ttttccagca gttcatcata cacacgaact tctgtttctg
    16321 ttgctcttcc tagatctgca tttagatgga aaagcagtga atcttcataa atcgaacggt
    16381 ccaatacatt attgtcatct ttcattgctt gtttgatgct tgcaaaacgt ttattcaaaa
    16441 aataaatttg cagcaaaaaa gcatactgtt cagggtttgc ataaaataag ggcaagactt
    16501 cattatcatc aatcgattca taaaatgcct gactatcaaa gtgttcagcc atcatttctg
    16561 ttaaacttga ttttccggca ccaattgtac ctgctaaaac gatcacgctc atttacctcc
    16621 agctcacttc atcactaaat attgtgttta actccaacct ttttaaatat acccccaata
    16681 tctagtagtg tcaattgtat ttttttctag tcaaagaaga aaaaaagtca aaaaattctt
    16741 aagaaaaaag tgttttttct ttagaaaacg tattcttagt tttacttctg agatggtttt
    16801 agtaaaataa aggaggaatg ttttttgaga cccttagtgg acaaaaaaat tcgtgaagca
    16861 gcgcaactcg ttttgggcgc tttatttttt gcttaaaaat cacttttacg tgagaaggag
    16921 ttagattatg gcaaactatg gccaaggaga atcaagcgga aagatcatat tgatgggcga
    16981 gcacgcggtt gtttatggag aaccagcgat tgcctttcct ttctatgcaa caaaagtcac
    17041 cgcattcctt gaagagctgg atgcaatgga cgatcaactg gtttcttcct actattcagg
    17101 aaatttagcc gaagctcctc atgcattaaa aaatatcaaa aaattattca ttcacttaaa
    17161 aaaacagcat gacatccaaa aaaacttgca actgaccatt gaaagcacga ttcctgctga
    17221 acgtggaatg ggatcaagcg ctgcagtcgc cacagcagtc actcgtgctt tttatgatta
    17281 cttagcattt cctttgtctc gtgaaatact attagaaaat gtccagcttt cggaaaaaat
    17341 cgcccatggt aatcctagtg gaatcgatgc agccgctact agcagcttgc agccgattta
    17401 ttttacaaaa gggcatcctt tcgactactt ttctttgaac atcgatgctt ttttgattgt
    17461 cgctgataca ggaatcaaag gacaaacaag agaagccgtc aaagatgtcg ctcacctctt
    17521 tgaaacccag cctcatgaaa ctggacaaat gatccaaaaa ttaggatact tgacgaagca
    17581 agcaaaacaa gcaatcattg aaaattcacc agaaacgttg gcacagacaa tggatgaatc
    17641 acaatcactt ctggaaaagc tgacaatcag caatgatttt cttaatctat tgatccaaac
    17701 agcaaaagat accggggcat tgggtgccaa attaactggc ggtggacgcg gtggctgtat
    17761 gattgcatta gcacaaacaa aaacaaaagc ccaagaaatc agtcaagcac ttgaagatgc
    17821 gggtgctgct gaaacttgga tacaaggatt aggagtacat acctatgttt aaaggcaaag
    17881 cacgcgcata taccaacatt gctctaatca aatattgggg taagaaaaat gaagaactca
    17941 tccttccaat gaacaacagc ctttcgttaa cattggatgc attttataca gagacagaag
    18001 tcatcttttc tgatagctat atggtagatg aattttatct agatggcacc ttgcaagacg
    18061 aaaaagcaac aaaaaaagtc agtcagtttc ttgacctttt tcgtaaagaa gccggcctct
    18121 cactaaaagc ttcagtaatc agtcagaatt tcgttcctac cgcagctgga ttagcctcct
    18181 ctgccagcgg gctagctgct ttagcaggcg cttgcaatac tgctcttaag cttggattag
    18241 atgatctctc tctttcaaga tttgctcgac gcgggtctgg ttcagcttgc cgaagtattt
    18301 tcggtggttt cgtcgaatgg gaaaaaggcc atgacgactt aagttcttac gctaagccag
    18361 tcccttccga ttctttcgaa gacgatttag caatggtttt cgttttgatc aacgaccaga
    18421 aaaaagaagt gtccagcaga aatgggatgc gtcggacagt cgaaacatcc agtttttatc
    18481 aaggctggtt agattccgtt gaaggggatc tatatcaatt gaaacaagca atcaaaacaa
    18541 aagatttcca acttctcgga gaaacgatgg aaagaaacgg actaaaaatg catggaacga
    18601 ctttagctgc ccagcctcca ttcacttact ggtctcctga cagcttaaaa gcgatggatg
    18661 cggtgcgaca attgagaaag caaggcattc catgctactt tacgatggat gctggcccta
    18721 atgtcaaagt tttagtggaa aacagccatt tatctgaggt acaagaaaca tttaccaaat
    18781 tatttagcaa agaacaagta attactgcac atgctggtcc aggaattgcg attattgaat
    18841 aaagggagat ttttatgatt gaagtatctg caccaggcaa actctatatt gccggagaat
    18901 atgcagttgt tgaaacaggc catccagcag ttatcgctgc agtcgatcaa ttcgtgacag
    18961 tcactgtaga atctgcacga aaagtcggaa gtatccaatc tgcacaatat agtgggatgc
    19021 ctgtacgttg gacaagacgc aacggagaat tagttttaga tattcgggaa aatccttttc
    19081 attatatcct tgctgctatt cgcttgactg aaaagtatgc acaagaaaaa aacattcttt
    19141 tatcctttta tgatctgaaa gtaacaagtg agttagacag ttcaaatggc cggaaatatg
    19201 gattgggttc tagcggtgcc gtgaccgttg caacggtcaa agccttgaat gttttttacg
    19261 cgttgaattt atctcagttg gagattttca agattgcagc actagccaat ttagcagttc
    19321 aagataatgg ttcctgcggc gacatcgctg ctagctgtta tggtggctgg atcgctttct
    19381 caaccttcga ccatccttgg ctccaagaac aagaaactca gcattctatc agtgagttac
    19441 ttgccctgga ttggccaggt ctatccattg agccattgat tgctcctgaa gatttacgtt
    19501 tattgattgg ttggacgggt agccctgcct ctacttctga tttggtcgat caagttcacc
    19561 gttcgagaga agataaaatg gtggcttatc agcttttctt aaaaaatagt acagaatgtg
    19621 tcaacgaaat gatcaaaggg tttaaagaaa ataatgtaac gttgatccaa cagatgattc
    19681 gaaaaaaccg acaattactg catgatttat ctgcaatcac tggggtcgtc atcgaaacgc
    19741 ctgctttgaa caaattgtgt aatttagctg aacagtatga aggagccgca aaatcttctg
    19801 gtgcaggtgg gggcgattgc ggaatcgtaa ttgttgacca gaaatctggc attcttcctt
    19861 taatgagtgc atgggaaaaa gcagaaatca ctccactgcc gttacatgtc tatagcgatc
    19921 aaagaaagga aaaccgatga atcgaaaaga cgaacatgtt tcactagcta aagcctttca
    19981 tgataaacaa aaaaacgaat ttgacttcgt acggatcatc cataaccctt tgccgcaaat
    20041 agcagtttct gatgtcgatc taagtacaca ggcagttggg tttacactaa gcagcccatt
    20101 ttatatcaat gcgatgactg gcggaagcga aaaaacaaaa aaaatcaacc aagatcttgc
    20161 aatcgtcgca agagaagcag atttgatgat tgccactggt tcagtcagcg ctgccttgaa
    20221 agtcccttct ttagccgata cttatacgat tatgcgacaa gaatatcctc acgggaaaat
    20281 cattgccaac atcggtgcag ggacttctgt cgaaagagcc aaagaagcta tccgattgtt
    20341 tcacgcagat gccttacaga ttcatttgaa tgcacctcaa gagttggtta tgcctgaggg
    20401 agaccgtgat tttaccaatt ggaaagtact tattcaagaa actcaaacag ccattgacgt
    20461 ccccctcatc gtaaaagaag tcggttttgg catgacaaga gaaacgctca atgatctagc
    20521 tgctttagga gttcatacag ttgatatcag cggtcgaagc ggaacaagct tcacccagat
    20581 cgaaaacgcc cgtcgctcca agcgggaact gagttattta gctgactggg ggcaatcgac
    20641 agtctcttca ttgcttgaag caaatgaagc agacacttct atggaaatcc tagcctccgg
    20701 aggtatccgc aatgcctatg acatatttaa agccctttgt ctcggcgcaa atgccgtggg
    20761 tacttcagga accgtactga cgcatctgat gaatcacggc gtagaagaaa ctattatact
    20821 gatgaagcaa tggcaagaag agcttcgtct gctttatact atggtcggcg caacgaatac
    20881 cgcggcccta caccaacaat ctctgatctt ttccggacca gtgaaggatt ggtgcgaagc
    20941 aagagggatc gacttagtga agtatggaag acgcacagaa aagagcgtgg gacaaaagta
    21001 aagaacactt ttgtctcacg ctctaaacac gtacaaacgg cggaagtaaa agcaactcct
    21061 tcggaaataa gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat tccttcttat
    21121 ttcttggagt taaatgcttc tgtcccagcc tcttttttcg aataaatgat gtttaatcag
    21181 ctgtccttcg gtattcgttc aatccgctga tttcacaacc tctccactaa acagtgtact
    21241 aaagctcttt taaggttgtt ttccgatata ggcaagtatg cctccgtcca catacaagac
    21301 atggccgtta acgaaatcag atgcgctaga agccaagaag acagatggtc cagccaaatc
    21361 gattggctcg ccccagcgtg ctgctggcgt acgtccaacg ataaattgat cgaatggatg
    21421 acgttcaccg ttttcttgtg tttcgcgtaa tggagcagtt tgcggtgtag caatataacc
    21481 tggtccaatt ccattacatt ggatattgta ttgaccgtat tcagaagcga tgtttttcgt
    21541 cagcattttt aatccgcctt ttgccgcagc ataagcactg accgtttcgc gtcctaattc
    21601 actcatcatg gagcagatat tgatgatttt accgccgcct ttttcgatca tatccggaat
    21661 aactgctttt gaaacgatga atggggcatt taaatccacg tcgattactt ggcggaagtc
    21721 tgccgcatcc atttcgatca tcggtgtccg tttgatgatc cctgcattgt tgactagaat
    21781 atcaactgaa cctacatctt ctttgatctg ttgaaccatc gcttgaaccg cttcttcatc
    21841 ggtcacatcg cagacataac cttttgcatc gatgcctgct tctttataat gcgctatacc
    21901 ttcatcaact gattcttgat tcaagttatt aaatacgatt tttgctcctg ctgtagctaa
    21961 agagcgtgca atctcaaatc caataccata gacagcaccg gtgactaatg ctacttttcc
    22021 atctaaacga aacatatcca tactaaattc catcattttc tctcccttat gcttatttta
    22081 attgatccat ttgcaccata tccatgtctg tataggtgat attttctccg cacattgccc
    22141 agatgaatga gtaattgctt gtacctacac ctgaatggat cgaccagctt ggcgaaataa
    22201 tggcttgttc attgtctaca actaaatgtt ttgtttcatc tggtttgccc atcatgtgga
    22261 acacacgtgt atcttcattg gcataatcaa agtagacata agcttccata cgacgttcat
    22321 gtgtatgaca aggcatcgta ttccaagcgc ttcctggttc taaaatcgta taacccattt
    22381 gtaattgaca gctttcgcat acatttggat ggatgtattg gtagatttta cgttcattca
    22441 gtgtcaggcc ttcaccagtc tccattggtt ttacttggtc gatactgatt tttacatttg
    22501 gatatttatg atgagctgga acagaactaa tatagaattt agctgggttt tcagcatctt
    22561 gagaagaaaa tacaacatgt cgtgtttctt ttccgatata gtatccgtct tgttttttca
    22621 tttcttcttt ttgcccatcg atctcgatga atcctggtcc accgatattg atcacaccta
    22681 gttcacgacg ctctaagaag taatcaacac ctagttcttt gtctaatgtg atttctaatt
    22741 ctttttcagt aggtgtcact ccaccaaaga tcattcgatc gttgtgcgta taagtcaaac
    22801 tgattttccc tggttcaaat accttttcta ctaaaaattc ttttctcaat tgttccgttg
    22861 aataatgacg gatatcttct ggactgtgtg tataacgtgt ttccatttct tgcattttct
    22921 tctactcctt ctatcgaatg atttttccag agccgcatgc taaaaattgt gcgacttctt
    22981 cttgactaaa ttggttgcag tccccatgga tcgtatgctt caaggcagaa gctgccgtag
    23041 caaaatcaat gatttcttgc ggagacatat tggataaaat cccatggagc acgccacctg
    23101 caaaagcatc tccgccacct actcgatcca cgattggggt gattctatgg acttgggatt
    23161 ccacatattc atggttcatc cacaatgtcc ccttcaattc attttcactt gctgaatgaa
    23221 cggtacgctt ggtcgaataa aacacctgaa tattcgggaa cttttcctgc attttttgat
    23281 aataataaat tagaggttgt tcttctgctt ctggcgcttt ctcgatacct aacaaataaa
    23341 gagcatccat ttttccagct gagcagatat ctactaaagg taaaagctga tggattactt
    23401 cgctggcttc ttgctgtgtc cataattttc cacgatagtt gatatcgaag ctgatcaggc
    23461 agccagcttt ttttgcagct tctatcacct gtttcgtcat tttttgccat tttttagaca
    23521 aagctggggt gattcctgaa acatgaaata tatctattcc ttggaataac tcctctagcg
    23581 accattccaa atgatccatt tcagcaaaac ttgatccggc acgatcatag atcactgagg
    23641 cggcgcgttc gccactacca gtttccatat aataagtacc tagtcttgat ccaccagata
    23701 atacctgttt cgtatctact ccataacatt gcaagtgctt tttgactgct tttcccaatg
    23761 cgttatcagg tacttttgta gcaaaaatcg cttcatgtcc gtaattagct aaagaaattg
    23821 ctacgtttgc ttcccctccg ccataatggg cagcgaatcg ttcacttgaa tcgatacggg
    23881 ttccctgctc tgtggacaat cgcaacatga tttctccgag tgtcactact tttcccataa
    23941 gcagctacct cttgatttct ttcatttttg ctgcatactg ttgcgcgact tccgttactt
    24001 tgtcaaaatc tcctgtagct gcgggtgcta aaaggttccc acctactccg actgttacga
    24061 caccagcatc gaaccactct ttcatattgt ccagactcac accgccagtt ggcatgatat
    24121 tgacttgagg catcggcgcc ttgaaggcag aaatgatact tggtccataa gcgcttccag
    24181 gaaatagttt gacgatatct accccgcttt tcagcgctgt tttgatctcg gtaatagtca
    24241 tacatcctgg taagtaagga atttgataca gattgcacat ctctgccgtt tcttgatcaa
    24301 aggaagggct aacaatatac tctgcgccag ctaagatagc caagcgagct gtgacagcgt
    24361 ctaatactgt gcctgcgcca atcactattt ctggttggtc tttgtagaat gacaaaagtt
    24421 ctttgattac ttgatctgct tgagggactg taaaagtcaa ctcaatacca gttagaccac
    24481 ctttgatgat tgcgtggcaa gcattcaaag cttcttcttt gctttttccg cgtaccaccg
    24541 caatcactcc ggcgtttttc aatcgagata aaatatcaat ttttttcatc ttctccacct
    24601 atttcctatt tagaaatttt attttataac ttggaaatct atacccatat tatacggcag
    24661 aaaagaaaaa ttgcaaacgc ttttttcatt atttttgaat tctttgctcg atttcgcttt
    24721 ttgtttgctt gagggcactg attatttgtt cttttgtctc atctgttaaa cgatatttcg
    24781 gcatacttac actaaatgca ccaatgattt gttcgttttt cacgattgag gctcctatac
    24841 aaaaaatatc acgttcgatt tcttcatcgt caaatgcgat gtgggtttct tttaccgttt
    24901 tgatttcctt tttcaaccgt aatgcattgg tgatcgtata ttctgtgtaa gggatcaacg
    24961 gatgcttttc aagataatca gtgtactgct cttcactgaa ttctgctaat acggctttgc
    25021 ccatcgcaga attgtataat ggtcgggtga ttccgatttt tgaagacatg cggatcgttt
    25081 gatgttttgg atctagtttg ttcacgtaca agatctcatt gttgtccaat acccctaagt
    25141 ggatagtctc atcgatcttt tgctgcagct gttctaaaaa cggtaaagtc aactctacca
    25201 aatcgatttg ttcaatgttt ttattcgcgt agcgaataag ctttgcacct aaacgatagt
    25261 ttttctctga atttttattt acgtagccga tcatcaacaa agtatctagt attttcaaga
    25321 ctgtagaaga ggtcattccc acaccctttg cgatcgtctg caaagagaca tcttggtttt
    25381 ccgctaaata gtctagtatt ttagaggctt tgatcaatac agttccataa ggctttttat
    25441 tttccatata atattctcct atttctttat aagaaaaatt atagcggaaa taccatcaat
    25501 ttaaaagaga tatccagata taaactacca tttctcttta caggcaattt aatgttgaag
    25561 atccgcttcg tttttacatc aaactttgat ataaagcaat gatttcttct actgtcgttt
    25621 ctcttggatt tcctggtgtg catacatctc gcaaagcatc ttctgcaatt gctggaatat
    25681 ctgcttcttt tacacctaat tcagaaatgg tttctgggat tccaaccgct ttgctcaacc
    25741 gatcgatctc accacaagcc gcttctctta catcttctaa agacatttca gctgctcctt
    25801 taatccctag aacaagagcg atctcacggt acttttctcc agtatattct ttgttatatt
    25861 tcatgacagt tggcaaaagt gctgcacacg ctacgccatg aggaatgttg taccatgcac
    25921 ttaacgggtg agccatcccg tgtaccagtc ctaaaccgac atttgagaag cccattcccg
    25981 caatatactg tcctaatgcc attttttctc gcccattttg atcgccatct acagaagctt
    26041 ccaaagaatg gccgatgatt tcgattgctt ttaaatgcag catatcagtc atttcccaag
    26101 cgccttttgt gataaaccct tcaatagcat gcgtcatagc atccatacct gttgatgcag
    26161 ccaatttttt cggcattccc atcatcatat cgctgtcgat gaacgcgacg attgggatat
    26221 catgaggatc aacacaaaca aattttcggt gatttacttc atctgtgatg acgtagttga
    26281 tcgttacttc tgctgctgtt ccagaagtcg ttggtatagc taatataggt aaacatggat
    26341 ttttcgtatc agcaacacct tctaaactaa tgacgtctga aaactctgga ttcgtcaaaa
    26401 taatcccaat ggcttttgcc gtatcgattg gcgaacctcc accgattgcg atcaaacagt
    26461 ctgcctctgc ctctttaaca aaagccactc catcttttac attttggatc gttggattag
    26521 gtacgatccc gtcgtataaa gcataagcga ttgctgcttt atctagaagt tctgttactt
    26581 ttgttgctat accgtgctcg atcaatcctt tgtcagtaat gacagctgct ttgccgaatc
    26641 ctcgctgctg aaattcaggg acgatcgact caatcgctcc ttttccaaaa tacgatgttt
    26701 catttaaaat cattcgatta ctcattttct attcctccta atttgtatta tttttcacaa
    26761 taaaaacgaa agaaccccaa gcaaccggtt gcccagttgc ttgttgctac agttcaaaga
    26821 ctggcatcaa ttcccaactg actggagagg catctggatt tgtctccatg atatcttcca
    26881 tgtacttcca ccatttttga ttgatagatg tatttgccat tttttcccat aacttttcat
    26941 cttcgatcac taagtaacca aataacaaac ttgtactcgg atcaagatag atcgaatagt
    27001 cgatgacccc gtgttcacga agtgctgtac gcatttctgg ccaaagttca tcatgtcttt
    27061 ttttgtattc ttcttgtttt tctgggtaaa ctttcatgca aaaagctttt ttcaccatgt
    27121 cagacacctg ctttcgtatg aacttcctcc aaataacctg cttttggagt gacaccaaac
    27181 gcatctgcta aatgccacag gttttcgtcc gtgattgttt gcaagattgg tccttgcgct
    27241 ttgacgtacg tatagacttc tgctgccttt tctgctgtct cgatcaaacc aaagacttca
    27301 tccatgtctt ttcctgaccc gtagattcca tgttgtggcc ataaaaccaa tcgagtttct
    27361 ttcatttttt cagctgttgc ttccccaatc tcatttgttc ccggaaccat ccacggaatg
    27421 atggaaattc cttctggaaa aacaactaag cattccgtac acatttgcca tagcgtacga
    27481 ctaaaggaac gttcgtctaa ttcatgcgta aaactcatcg ctaatagatg actagcatgg
    27541 caatgcataa cgatccgatt atctgggtct acttctaaac gggcgatatg actcatgaaa
    27601 tgacttggca actcgcttgt aggaaggcat tcgttttcca gcccccacaa aagttccagt
    27661 gttttgccat cttcagcaac tcgaacgatt ccaagattct cggcaggttc gctcgctaca
    27721 tttttaaaat atcttcctga accagttaca ataaaatagc atcctgctaa acggctggca
    27781 tcaaaaatca tcgagatgcg gcggatcact ttttcaggat ccaagaacgg tgtgatctct
    27841 tcttctttta gtaaataaga aatattcccg ccatttcttt catcccatcc caagcgataa
    27901 agattcgacg tcgtttcgat catttctttc acataaggcg cttgtaaaat atctattttt
    27961 ttcaatatag ccacactcct attttcttaa ttccaacacg tctttttgat attcctggac
    28021 ttcttccagc caatccaaac caactggaac ttgatttttg taacagaaat aattccatac
    28081 atcggcatac gggaaatctt tcaattcttc cgtataagcc attcttgaag taaagtcaaa
    28141 agccagctcc atttctttca atcgctcaac tggttccagc atagctttca gcagtgcttt
    28201 ttgtgtattt ctcgtaccga tgacccaagc agcgatacgg ttgatcgttg catcaaagaa
    28261 atccagaccg atatttgttt tttccaacaa ttcgttacgg actaattctt tagcgatttc
    28321 ctgcaattca tcatccatca aaaccacatg gtctgaatcc caacgcactg gacgggaaac
    28381 atgcaacatg attcctttgc tgaataaagc taatgaagat aatttattgg aaatcacttc
    28441 tgttggatga aaatgtccag catctagaca aacaagtttg tcacgagtca acccgtaacc
    28501 catataaaat tcatgggaac cgactgtata agcttcagcg cctaaaccaa atagtttgct
    28561 ttctactgca tcttgtacat accgttcatc taactcttct gtaaaaattt catcgagtga
    28621 ttccattaaa cgttcccgtg gggtaaaacg atcaatcgga ttatctttca tcccatcagg
    28681 tacccaaaag ttattgatac ttgtttgccc agtttctttc ccaaagtact ccgcgatttt
    28741 gcggcttctt ttcccgtgtt cgatccagta ttcacgaact tctttatctg gatgagccaa
    28801 tgtaaagccg tctttcatca ttggatgcga aaagaaagtc ggattgaagt caagaccgat
    28861 ttcttctttt tttgcccact ctacccattt ttcaaaatgt ttcggctcaa tttcatttag
    28921 atcgacagat tcttctgtat ccaaatagat agcatgaagg ttcaatttgt gtttgcccgg
    28981 tatcaacgaa taagccttct ccagatcttg tctaagctct tcaggtgttc gtgcggctcc
    29041 tggaaaattc cctgtcgcca tgattccacc ggtcaattcg ccatccggtg tcaagaaacc
    29101 tttgacatca tctccttgcc agcaatgcat agaaattttg atgtcctgta tcttttctag
    29161 tacagcatct gtatctacac cgatagttgc atatttttct tttgcttgtt cgtaatttct
    29221 ttcaatcgtg ttcatacgat tactcctttg attttattca cgtaccattc catcgtgttt
    29281 tgcttatttt catctgggta aaaagtttca catggaaacg actgtttgat tacatttctt
    29341 gcttgttcta tattcgaaaa ctgacctgta ctgagcattt gcatggcaac attcccgatt
    29401 gctgtggctt cactaggtcc tgcttctaca atgattccgg cataatctgc tgtcaattga
    29461 ttcagtagac gattattcga tccgccccct acgatgtgca gcttttccaa tttcgttcca
    29521 gttaagtgtt ctactttgat cagctcttgt gcgtaacaaa gagcaagatt atcatacaca
    29581 caacgagcga tagctcccga tgagacaggg actggctgct ctgtttcaaa acagtattgc
    29641 tgaatctctt ctatcatatt tgggggattc aaaaatcgag ggtcattgat ttccatcact
    29701 tgctgcagcg gtttttcttt tgcagcaagc tctgccaatt ccgcataact gtactcgtac
    29761 tcttgcattc gggcaacttc ctggatcaac cacatcccca tgatgttttt caaaaaacgc
    29821 accgtgttat gggcacccca ttcattcgta taattttcag aaaaagcatt gcgagaaaca
    29881 ttggcgatct ttgtttcaat ccctaaaagc gaccatgtcc cactgctgat ataaccccaa
    29941 cgttctcctt gacctggcgt tcctaataca gctgacgccg tatcatgact tgctactgtg
    30001 ataaaggtca catctggcaa atcatatttt gaaaattgtt ctttttgcag atctcctagt
    30061 atcgttcccg gctctgtcaa tggtggaaat aattccttcg agacaccgat tttttcaaga
    30121 agttctattt cccattcttt tgtccctgca ttcagcagct gcatagtaga tgcattagtt
    30181 ttctccgtca ccatgttacc agtaaagaca taccctaaat aatcaggtat cagtaacaat
    30241 ttatgtgctt ttgccaaatt ttctttttct tcagcaaaca attggaacaa ggtattgaaa
    30301 ggctggatct gaatccctgt ctgctcatac aacttatcta gagaatagat ttcagaaaac
    30361 tgttctactg ctccattggt acgcttgtcc cgataagcaa tcggatcatt tatccgatcc
    30421 ccttgttcat caatcagaca gtaatcgact gcccatgtat cgatccccgc aaaaaggcga
    30481 tcaatccctg tctgctttaa tttttcaaat ccaatcaaaa tctctttgat aagataatcg
    30541 atcttccagc gatcgtgacc gtctttgttc cgaaagccgt ttttgaaccg gtgtacttct
    30601 tccaagatca aagaaccttt tgcatccctc gtacttttca ttagtcgtcc gcttgatgca
    30661 ccgatatcga tggcaacaaa tgttggattc atttctccac ctcttttact ttattgttga
    30721 ttagcacttt attaataaag cgttatcatt tattgacaat gctatcataa tacagaatct
    30781 tatattttgc ttcacactat tttggtatat aattgcatta tcttgacaag ttgggagtgt
    30841 ttacatggat tactgggaaa aagccaacca ctcatggtcg gaagactcaa aaagagtgat
    30901 cttgacgcct acacaaagaa gcaggaattt atttttttat atccaagaaa tcggttactt
    30961 caaagcacca atcccttact atactgaacg agcacattta ccttcttact tgataaagtt
    31021 tactttgtct ggcaaaggtt cgcttacata taatgataat cagcaacagc taaaagctgg
    31081 agacttattt tttattgact gccaagaata tcagcgttat caaacgatca gcgaagaacc
    31141 atgggaaatg gattggatcc atttgaatgg tcagaacgtc caatcatttt atcaggagtt
    31201 cacaaaagac ggccataaca ccttccattc aacaggagat ccatcagaaa acaagatcca
    31261 ccatttgatc acagaattga tccacatgca acaaggcacg aatgcccgta ccgatttcca
    31321 gtcctctgta gctatccacg agttgctgaa tgaactgatt ttgcaaaagt atcagctaga
    31381 tttcgaagaa gaggatattc ccgcctacgt ttacaaactg aagcaatact tagacgaaca
    31441 tttcaaagaa acgattacac ttgatcaatt agaacaacaa ttcttattga ataaatatca
    31501 gctgagcaaa gatttttcca aatttatcgg ttctccacca atcgattatt tgatcagcaa
    31561 aaaactttct tacgctaaag accttcttcg gtatacagaa tttacggttc gaatgatttc
    31621 cgaagaaata gggattgaga attttgctta ctttagccgc ctgttcaaag caaaaacagg
    31681 actatcgccg agagactttc gtaaattcag ctgattcata taatatgtac gtcatttttt
    31741 caaaatattt tgaaatatat agataaaaat aaaataaccg cagtttctgc ttctatgtaa
    31801 acaacagcag ctactgcggt tattttttag tgatcattct cattgttcat cttcaaaatg
    31861 ttcataatga accaactgtt tctgtgtatc acgtttcaaa aattctttag gcgttatgcc
    31921 gaactctctc ttgaatgctt tcagaaaatg cggataagaa gaaaaaccac ttttactata
    31981 tacagcacta gagctgcggt attctcgcaa caagtgcttg gcatagatca gctttttctt
    32041 cattacatac tgatgaaacg taaatccagt gtacttttta aattctcgtg tgatatggta
    32101 tttgctgaca aaaaactgct tttccatttc ctctaaagaa agcggatgag ataaattttt
    32161 tgagatatat tgtaacattt gttccacacg ctcattagga actacagcat tctgttcttg
    32221 cgcactctct tctttttgta caacttgatt gagaaaaatc aagtattcta ccagagcttg
    32281 ttcatatttt atgtcttcac cgtaaatttt tttatcagga ggatggtcga taaatgataa
    32341 tttttgcttc aatacttcct gttctatttg caatacacga ctcctcttct ctcccattgg
    32401 ttgaaaacaa gccgatagat tagaccatgg cgtggaacga ctttctagaa aagaaggggt
    32461 gacaaagata tagacacgct cgaatacatc tgaagattgg cggacgatac gatgcaaatc
    32521 attggaatgg atgagcagca cacttcctgc tttgatcgta aattgtcgtc cgttcaaata
    32581 aaaagtcgct tctcccttta atgtagcatg gatctcatag aaatcatgat gatgatagat
    32641 cgttttattt tggctgacga catctttgac atgatagatt tcatactgat cagaaaccat
    32701 cgtattgact tgttcaccgc tgattttctt ttggagcatg tgccgcacct ccttttgttc
    32761 acttatgcac aattttatta taccacgttt tttgtaatca aaaagagctg cttttatata
    32821 ctcttataaa aaagaagaga cgtggcatct tctagccccg ccccctccat tctaaatatt
    32881 agttaaccaa cgtcttcttt acattattca agaagacttc ttccataacg aatcccatca
    32941 tcttttgttt cttcaagaac cacatacagg tacggacgat tcttcatgat gatttctttg
    33001 atttttgtgt actcgatcac accgtctccc aaatttaccg gcacgatttt ttcctgttcg
    33061 acacgaaaat ctttcaaatg aaccgcacat atcttttcac caaaacgttc aaaagcttct
    33121 tctaccaatt ggacttgttc ttgataatca ctacttgtga tcaaattggt cggatctaaa
    33181 atgattccta gatagtccga atctactgct tggatcagct gctctaccct tgctaaagaa
    33241 tacaccggat gattcaaacc tggttctatc cccaccatca tttggtattt ttctccagct
    33301 tttaccaagc gacggataac ggacacagct tcagcaaatg cttcatctgt gaaattttct
    33361 tccgtatatt ggatttccgg caaaacacat ccagtttccg aagcaaccat cgacgcacca
    33421 aaggaagaag catagcgaag atactgctcg aactttgtca gcaactcttg tcgtatcgtt
    33481 aaatctggat gaatcatatt gatatagcaa cttaaaattc ctacggtcac ttcttgcttt
    33541 tctaaaactc gtttgacata atttcccatc ccagaattga tctcatttgc gccagaaggt
    33601 atttcaggaa acgaaagacc taaggcgagc tgcagtgtat gaatcccttg ttcttttgtt
    33661 ttttctgcaa gatcttctat cgtttggact tcggaaagat catgtcctct aattgtaatg
    33721 ttcaacataa ctattctcct aactcagcat attgggtagc cacatgacga tttgcgggaa
    33781 gtaagtaatc aaaaacaaga cgactaagat aaccccataa aaaggaagaa gcggtttcag
    33841 cattgcctct gcttttacgc ctcctacact tgcaccgaca tatagtcctg tacctactgg
    33901 cggcgtgatg gagcctacac acagattcat gattgaaaac aacccgtaat gtacaggatc
    33961 aacccctaca cttgtgacga ttggtaaaaa tattggtgta aaaatcaaga tagcaggcgc
    34021 cacatccata aacataccca ccagtaataa cacaagattg actaataaca gaataataaa
    34081 tttattatcc gttacgccca taatcaacga actaattgcc tgaggaatac cggtaaacgc
    34141 catggcgaaa gacatcatgg aagaagtagc caataagaac atgatcgtcc ctgacattgc
    34201 tactgattga aacaacatat taggtatatc ttttagtttt accgttttat agtaaaacat
    34261 agcaatcaac agggagtaaa tgacagctat cgctgaagct tctactgctg taaatatccc
    34321 cgtcaagata ccaccgataa tgatgacaat caatagaagg ctaggaatcg cctcttttat
    34381 tatttttcca gcatgagcca tctgtccttt ttcgacaaca gggtatttat tctttttagc
    34441 aacgatgaat gctactagca tgattcctag cgcccacaaa gcgcctacga gataacctcc
    34501 cataaacaaa gcagagatcg aagcaccacc agcaacaagt gaatacatga taaaagcagt
    34561 acttggagga atgaccatac ctgtcggagc tgacgcgata ttgaccgctg tcgcaaactt
    34621 ccggtcatat ccttcttcca cttgctgagg gatcaacact ccgccaatcg cggtagaagc
    34681 ggcaatggcc gagctagaga tggaaccaaa taaagcattc cctaacacat tcgtatgagc
    34741 caaagccccc ggcacgcgcc cgacgaacaa catcgcaaaa tccactagtt tcttagctat
    34801 ccctccatta ttcatgataa tgcccgagag aacgaaaaac ggaatagcga tcagcgaaaa
    34861 actattgata cttcccacca ttttttgagc tgaactaaaa gcagaaacat caaacggtat
    34921 aactaacaat aaagtcatca tcgatgagaa tgcaatactt atagcaatcg gcatccctaa
    34981 tacaagcaac acaacaaata caaaaaataa cactaatccg gcttctattg ccattttatt
    35041 cctccatttt tatatttttt cttgaattgc tggcttgttg cttaatgtat cgattagatt
    35101 gatcaggcta tagataatga tgagtacccc cgatacaggt actgacagat aaacatatcc
    35161 cataggaata cttaaagaag gcgagatctg ccccattgtc aatgtgacag cattccatcc
    35221 gccatacacc atgatcatcg cagcaaatac cagaaataaa ctttgaacaa caacttctaa
    35281 aattttactt tttttgccag ttaatttttc acttaaaacc gttacggcta aatgtgcttt
    35341 ttgtcccaca acatacgcgg aagacaacat ggcaaaccag acaagaccga atcgaacaag
    35401 ctcttccgtg accgtatttg gatttcctaa aaccgttctg gaaaatactt gccataaaac
    35461 aacagcgacc atcccaacaa gcaaaacagc tcccaggatc tctaatacct tgtttaaaat
    35521 cattttcatc acagctacgc tccttgctct tggatctttt gataaaggtc tttgtaggta
    35581 ggatcgtttt tgaatatatc atgaagtggg gcaactgcct ctcgaaacgg tgtattatct
    35641 acatcattga attggactcc atgttcttct tgtgctaaag ctttttcttc ttcaattgct
    35701 tttgcaaaag cttcaatttc aaaaaccgtt gattctttcg ctgcttcttc aatggctttt
    35761 tcctgctcat cagttagctg ttctttgatg gcatcattca tgatgatgat atctggcaca
    35821 cgtgtatgct catcatagga atagtattta gccacaccac catgtccagc tgtatacaag
    35881 acaaattcat tgttttctga tccgttgatc aaattggatt gaagagacgt gtacacttca
    35941 tcacttccca taggtacggg cgaaccgcct aaaagctcta ccattttgat agcggtttcg
    36001 ctttgcatca cacggatctt ctttcccttc aaatcttccg gcgtatggat cggaccgtct
    36061 accatataaa agctgcgctg accagaatca taataggtca atccggtaaa tcctaaattt
    36121 ttggtcgatt ggtagattgg ctccattatt tcttcattat ccatcacctt aaagaaatgt
    36181 tcttcatcat tgaatagata aggaactgaa aaaatcgaat aatctttaga gaaactttcc
    36241 aacgctgagg cacttacttt tgtgaaatct actgctcctg actgtgtcaa ttcgatcagt
    36301 tcacgttctc cacccagttg tccatctggg aaatactgga tctgtacgga accatctgtt
    36361 ttttctttta ctaaacgccc aaattcattc attgcatcaa ttactggctg gctgttgctt
    36421 gcataagcaa agcgcaaggt aactatctca tttacatctg catctgcgac agttgccaca
    36481 ctagaattat ttccgcagcc gcttagacct agcagaccta ggctaagcga acttgctgca
    36541 aacagcagtg atgttttttt catatgggtt tcctttcttt taacaataag agacgagcaa
    36601 ttctgtcaaa caaagcaccg ttaacgactg tccataaggc attgctgtga ttccgatatt
    36661 ccgataaaaa tctaaactgt cccccattcc tgtcccgatt gaaacgtttt gaacttctcc
    36721 tttttcatcg atttgttcaa gcaatccttg gatagcacga taagcgactt ctttatattc
    36781 ttgtggtaaa taacgtttat ggaccgcttt caaaataccg taagcaaatc ctgcagttgc
    36841 agaagattct acgtaagaag aaggatcatc caacaacgta tgccataaac cgctttcaga
    36901 ctgataagtt tttaatgcac gcacttgtgc ttcaagtgtt tcgatcaata atttgcgcaa
    36961 tgcatcttct ttcgataatt ctaagatttc aatgatctct ggaatagcaa tcgtcaacca
    37021 gcagtttcca cgagcccaaa atgcttcggc atagttatga tttccttcaa acgtccagcc
    37081 gtgataccac aatcctgttc gtttatccat caagtatttg atatggatca taaactggta
    37141 acgagcttct tctaaatatt ctgggcgatt caacagtttc ccgatttttg ccaaaggaag
    37201 cactgtcatc atcaatgtat cgtcccacaa ctgattctta ttttccggtc catatgtggc
    37261 atgctgtaac ccgtcttcat ttgtccgagg catgtcattc atgacccatt ctgcccattg
    37321 ttctaaataa ggcaaatagc gtgaatcttt cgtgtcttca tacaagtaag ccatagtcaa
    37381 tagcggtgcc attgtattga cgtttttggg cggagcgcct tcttccatac gatcctcaaa
    37441 ccattcattg accacttgat aagcgcgagg attttttgtc atctggtaat ttttataaat
    37501 accatataga ccgacacctt gtggccaatt ccacactgtc cagcttttgt catctacttt
    37561 cagtccatca aagtccaaca aaaattcacc attatcgtct ttgatcgttg tcaggttttc
    37621 aacgagcagg tcaatttttt ctttcactaa ttctttaggt acaaaaatct cttctttaat
    37681 aatcatcttt acgccacctt tttaaacgct ttcattttat atccttaata tagcagtaat
    37741 accgtccact ataaatatcg ctttttgaac aaaaactgtc taaaattgac ctaaatgtta
    37801 aataacaaaa gtaactttca gttacttgga aattaaaaaa agaacttgga gaaacaacgt
    37861 tttccaagtt ctttttcatc tattttctta tcttttttct acgctttctt ttgcttatcc
    37921 gttgtaagca tcaatgatga tctgtttcaa ttcagagatc aatggttctt tcggattagc
    37981 tgtcgtacat tggtcttcgt aagctaattc agccatacgg tctacggttg tatctagtgt
    38041 ttcttgtgtg actccttgag cttttagact catgttgatg ccgacagatt ttcctaattc
    38101 ataaacagcc gttgctaaag cttcgactaa ttcctctgtt gtttcgcctt tcagacctaa
    38161 gaattttgcg atatctgcgt aatctgtatc tgcacggaaa tagtcatatt tagggaacat
    38221 cgcatgtttt tgtggatctt ttgcattata gcggataata tgcggtaaaa gaatcgcatt
    38281 tgtccgtcca tgagggatcc cgtattcccc gccgatttta tgtgcgactg agtgacaaat
    38341 acctaggaat gcgttagcaa acgccatacc agccattgta gaagcgttgt gcattttttc
    38401 acgtgattcc atatcaggtg tttttactga tttttctaaa tagtcaaaga ctaacttgat
    38461 tgcttgtagg ctcaatccac gtgtataatc tgaagccatg actgaaacat aggattcgat
    38521 tgcatgtgtt aacacatcca tcccggtatc tgctgtgaca gatgctggaa ctgacatgac
    38581 gaattgagga tcgacgattg cgacatctgg cgtcaatgca taatctgcta acggatattt
    38641 cacatgtgtt tcactgtcag tgatgaccgc aaatggcgtt acttcagaac cagtccctga
    38701 tgttgtcggg atacatacga attgtgtttt ttctggtttg tcgatcttat atgtccgttt
    38761 acggatatcc aagaattttt gttttgcacc aaagaaagat gtgtctgggt gttcatagaa
    38821 catccacatt cccttagctg cgtccattgc agaaccgcct ccaagagcga ttactgtatc
    38881 tggcttgaag tctgccatca gtttcgttcc tgcgtatacg gtatttgtcg atgggttcgg
    38941 ttcaacatct gagaagactt cgatcttcac atcattttta cgtcgtgcca atacttcacg
    39001 aactgtatcg cagtaaccga attggaccat accagggtca caaacgatca tgacacgttc
    39061 aacgttttcc attttctcta agtacaatag agagttcttt tcaaagaaga tttttggcgg
    39121 taatttgaac cattgcatgt tatttctccg tttcgctaca gttttgacat tgattaagtt
    39181 tacagcagag acgttacgag aaacagagtt cttaccataa gaaccgcatc ccaaagtcaa
    39241 tgacggaatc atttcgttat agatatcacc gatgccgcct tctgcagatg gtgtattcac
    39301 taaaatacga caagctttca ttcgaagacc gaatttgaca tgcaactctt cgttttctga
    39361 atggataact gctgtatgtc ctaatcctcc aagattcaac ataccttcac acaaatcaaa
    39421 cgcatggtcc gtgttgttag ctttgatcat ggcaagaact ggagaaagtt tttctcttga
    39481 tagcggataa tctgggccta cgccttccaa ttcagcaatc agcattttcg ttccttttgg
    39541 tacactgatt cctgccaatt ttgcgatttc catcgcagaa tgtccaacga ttgatggatt
    39601 gaccgcatat tttccttcgt tcatcactgc atcttctaat ttttgcaatt catctggttt
    39661 tacgatataa acttggtgtg cttggaattc tgcttttact gctgcataga tttctttatc
    39721 cacgatcaca gcttgttcag aagcacaaat cattccatta tcaaatgttt tcgaaacgat
    39781 caaatcgttc actgcacgtt taatttttgc tgttttttca atataagctg gtacgttacc
    39841 tggacctaca cctaaagctg gttttcctgt agagtaagca gacttgacca ttccagctcc
    39901 acctgtcgct aagacgatcg cgatacctgg atggttcatt agcatagaag tcgcttcgat
    39961 cgaaggatgt tcgatccatt ggatacaatt ttcaggagct ccggcagcga tagcagcatc
    40021 acgtaccact cgtgctgctt ctgcagaaga tttttgggca cttggatgga aagcaaaaac
    40081 gattggattt cttgttttca acgcgatcat tgatttgaaa atcgttgtgg aagtcggatt
    40141 cgttgttgga gttactccgc aaaccacacc gactggttca gcaatttcaa tcaacccttt
    40201 ttggacatct tcattgatca caccaactgt tttatcatgt ttgatattat gccaaatata
    40261 ttcggacgca tacatatttt tgattgcttt atcttcgtaa acaccgcggc ctgtttcctc
    40321 tacagccatc ttcgctaatg gcatatgttg atccaaagct gccattgcca tttcatgcac
    40381 gatatggtct actttttctt gatcaaagct ttccatttct ttcaatgctg catttgcttt
    40441 ttctgccaaa tcatcaatca ttgcttgtac gtcaattgtc ttcgtttttt ctttttctat
    40501 tactttagcc atcattatcc tcctaatggg tcatggttat ttgttaaata attcacatgt
    40561 atatcataca atatttattt ttctatgtaa acactttttt gtgatttttt tcacagttat
    40621 ttttaaatat aaaattgctt tatttacagg tgtttgtata gaaaaatata taaagttatt
    40681 tattattatt tatatgacac acccgattat tcaatattga gcaatatatc ccatgctctt
    40741 atctctttct tttttgaata aaaaatgagg taggacatct ttctgcccta cctcgtcttt
    40801 aaataagctt tgatacttat ttttcttcct tctcttctgt ctcttccagc gtttctgttg
    40861 tttcagtttt tacttcaact gtctcagctg gttcttctgt tgtttcaaca gtagtcgttg
    40921 catcatttgt tacgacagtc cctggtttga ccgttttgat tgctgcacga tcgtactcaa
    40981 ggaagatccc ttcgcagtct aaaacaactg tccgtttgtc attgtcgatt tctgaaacaa
    41041 ctccatgtaa tccgccgatc gttacgactg aatcacctgg tttcatgcta tctaacaagt
    41101 tttgacgttc ttgctgttgt ttcttttgcg aacgtgacat aaaaaaccac attgctaata
    41161 gcgcgataaa catcacaagc attggtaatg ttcccatttt tttcacctca ctaattctgt
    41221 atctacaaaa aacactttag cagaaaaatg ctgataacac tagtttttta cttaattttt
    41281 aaaagatttt cctttagaag ctttttgcgt tttctttatt gaacccgtat tcttcaaaaa
    41341 aggcttctct aaattcaagc aaattatcat ccatgattgc ttgacgtact tgtttcatta
    41401 gattcaacaa gaagtataaa ttgtggtaag aagtcaaacg aatcccaaat gtttcatcac
    41461 atttgatcaa atggcggata taggcacgtg tatagttttt acatgtataa caatcacatt
    41521 tctcatcaat tggacggaaa tcatgggcat atttcgcatt tttcactact agacggcctt
    41581 gagaagtcat acatgtgcca tttcgagcga ttcgagtagg caagacacag tcaaacatgt
    41641 ctactccacg gataacacca tcgatcaatg aatcagcagc accgacaccc atcaagtaac
    41701 gtggtttgtt ttcggggatc aacggtgtag tgaattctaa tacacgattc atttctgatt
    41761 taggttcccc gacagataac ccgccgattg agtaaccagg gaaatccatc ccgactagat
    41821 ctttcgcgct ttgacgacga agatcttcaa accctgctcc ttggatgatt ccaaataatc
    41881 cttgacggtc tggattagca tgagctttca atcctcgttc tgcccatcga gacgtacgtt
    41941 ctactgattt tttcacgtag tcgtaacttt catcgaatgg tggacattcg tcaaaactca
    42001 tcatgatatc agagcccaat ttattttgga tgttgattgc tttttctggt gataaaaaca
    42061 tacgcgaacc gttcaagtga tttttgaaat gcacgccttc ttcttcgata ttccgcatat
    42121 cacttaatga aaaaacttga aagccgcctg aatctgttaa aatcggttga tcccagttca
    42181 taaatttatg cagtccgcca gcttcttcta ctaagtcttc accagggcgt agccataaat
    42241 gatatgtatt acttaaaata acgccagcac ccatttcttt caactcttct ggggacattg
    42301 tttttactgt agctaatgtt cctactggca tgaacattgg tgtggggaaa gttccgtgtg
    42361 gcgtgatcaa ttcccctaaa cgcgcgccag tatgtttttc tttcttgatt aaacgatagc
    42421 gaatggcagg ttgcgtcatt catttcccta ctttctatat aaaatatctt gacaactccc
    42481 accatcataa tcgtttcaag tgctttttgc aagttccctc ggcttccttc tactttattt
    42541 aatattcttt tttttatcct ttttttatga ataacaaaaa aaagaaaaac attatgacag
    42601 aaatattttt tgatacatgg tatattggtg ttattaaaga aaaggaggga aaaatcatgc
    42661 aatcttctgc agaattaaaa cgccaagcaa aagagagtct aaaaggacgt tggggacaag
    42721 ctgttttact aaatctaatc cctacattga ttggtattgc tactattctt cttattatga
    42781 ttcctattat cttgtttgcc accaccatat atgatggatc agcgagcgtc tcagaagcga
    42841 caacttcagg aggcggtagt tcaggaggcg gtggcggaat tatttccagc atcattagcg
    42901 ctttgttcat gagcggtatt tcttggactt atcttgatat tttacgtgga caaaaagatc
    42961 agatcgaacc attcaaagat gcatttcgtg gattcaaagg tttgtttatc ggcggagtga
    43021 tcagcttagc tgtgctgatc tcgatcttta caacattatg gggtttgcta ttagttattc
    43081 ctggaatcat taaaagctat tcttattctc aaagctattt tatttactac gatatcgtcc
    43141 aagaaacagg acaaacacct aaagtactgg atacgatcac tgcaagtcga aaattgatgg
    43201 atggttataa aggacaactt ttctggttag atctttcatt tatcggctgg catatcttag
    43261 cattagcaac tgctggtatt ggttatctat ggctcagccc atacatttct gcaacaaaag
    43321 cagcatttta tgaacaattg ccaaaagata tttaaaagag agtgtgactt gtgaccgagg
    43381 gggtggcagg agaacaccgt ttatcgagag gcagtaaaag aaacattcag cccattagca
    43441 aaaaggaggt gtgacaacat tcatgtcaca cctccttttt gtatagttcc agtaaaaaga
    43501 aaatcaactt agaaacagtt aatcattcct cttcttctgc ttccggtaat cgatggaact
    43561 tgatcagttc attcaccgcg attggtacga tagataaaat ccctaccaag aaccagtgat
    43621 tcaaactgat gtgtactagg ccgaatagtt cttgcgtaaa tggcagcaaa gcaacagccg
    43681 ttgtaatagc taatgccagt aacgccattt ctaccaaagc tttattggtc gctaaattga
    43741 ctttgaagat cgattggctg ctgcgtacat tgaacacatg cagaatcgat gaataagcta
    43801 agatcaagaa tgcaacagtt tgaccgacat gctgacttgc gtctacccat gggctgatag
    43861 tatcgacata actacctaaa taataaccaa acaaggttac gatggtgaag acccctgcat
    43921 ttatggcaat tttttgcaat aaacctcgag caaagatccc ttcatttttc ggaatgggtg
    43981 gctgatccat gatgccgtgt tccgctggct ctcttcctaa agcaaatcct ggaagtccat
    44041 cagcaactac attgacaaac agtagttgca cagctgtaaa tggtgctccc catcctaaca
    44101 gcatcgcaat caaaacaata aagatctccg aaatattaca gcttagcaaa aagttgatag
    44161 ctttacgaat attctgataa accgaacgtc cttgactgac agcgtctacg atcgtcgcaa
    44221 agttgtcatc cgtcaaaatc atatctgcgg cactttgcgc cacatctgtt cctgtgatcc
    44281 ccatggcaca cccaacgtta cttgctttca acgctggtgc atcattcaca ccatccccag
    44341 tcatcgctac gactgcaccc gtacgttgcc aagatttgac gatccggatc ttgtcttctg
    44401 gcgttacccg agcatagaca gagagagctt tgacacgcgc atctaattct tcgtctgata
    44461 attgatgcag ttctgatcct gaaagtgctt ctgacggatc attcaagata cctaattctt
    44521 tcgctatggc actggcagtc accacatgat ctccagtgat catgactgtt ttgatgccag
    44581 cctttttcgc tcgcttgatt gctcctttac tttctggacg tggtggatcg atcattccga
    44641 tcagaccaat caaacgtaag tctttttcca gtgcttcaga agaaatatct tgcggttctt
    44701 cgtcataagt agcataacca acagcaatca ctctcagtgc ccgtttacca aagcgatcat
    44761 taacgatcgc cgcttgttct acatcgcctg aactaaagcg cggagcaaga acatcgaatg
    44821 ctcctttggt gattgagatg tatttttcgc ccatttggtg aactgttgtc atcatttttc
    44881 gttcagaatc aaaaggaagc tcgtttactc gtggatattt ttcttctaat tctgcctttg
    44941 tatgataatt ctcttcaaca gcccttacga tggctacttc tgttggatta cctttgataa
    45001 caaggtcgtc atcttcttgc tcgaccgtca catctgtaca tagtgcagcc attttcaata
    45061 tttccatcgc gctgttcgtc attgaatctt cgatattcgt tacttcatct tctttgctcc
    45121 atacccggcg gacgcgcatt tcattttgtg tcagcgttcc tgttttgtct gagcagataa
    45181 cattagcggt tcctagcgtt tcaactgctg gcaactgtcg gatgatcgca tgtttcctcg
    45241 ccatcttctg cacaccgtat gcaagtgtca acgtaacaat aacagtcaag gtttccggta
    45301 cagctgcaac agccaaggaa atcgaagtca tgaacatctc aaggagtggt tctccttgca
    45361 gttcaccaat cacaaatact aaagccgcag ccgctaaagc gatcatactg attcgtttgc
    45421 ctagctgatt caatcggacc tgtaaaggtg ttttttgcat agtattttcg ttcaaaagat
    45481 ccgcgatctt acccatttct gtagccatgc caatggcagt gacgatcgct ttcccacgac
    45541 ctgcagcaac cgtacatcct ttaaatacca tattaagttg gtcacctaat gactcatctt
    45601 cttcagcaat aaatgctgca tctttttcaa ctgcttcact ttctccagtc aacgccgatt
    45661 cttctacacg taattgtgat gcttcgatca aacgggcatc ggcagaaata gcatcaccgg
    45721 actctaaaac aagaatatca cccactacca gttgctctga ctcaacagtg gtcactttgc
    45781 cgtctcgtat gacagttgcc gtttgtttat tcatatcttg caaggattcc agtgcttttt
    45841 ctgcgtttcc ttcttggaca atcgccaata ccgagttgat cacaacgata gcgatgatca
    45901 gcagtccttc aaataaatcc ccatgttctg tagcaaatgc ggtataaaag gaaatcaccg
    45961 ctgctacaag aaggatgatc gttgtaaaat cggacaagct tcgaaagaat tttttgatca
    46021 tcgattcttt cggcgcctca tcgaatttat tcaatccctg cttttttcgc cgttcatcca
    46081 cttcttgtga agacaaccca gtatctggat ctgcttctgt taccttcttt acttcttcta
    46141 ttgtctgctt gtattcttcc atcctattcc tcctttaaaa tcttcgtaca aaaaaaggta
    46201 cttattttac tataacatcc tttttttatt tacttcaaat aaagggctta tcgattattt
    46261 gttaagaaag cgtaaaattt aaagtgctta tatttgcaaa cgctaccaaa ggatgctatt
    46321 atatagatgt aaggaaggag gataccatca aatagacaga agaatttctc gatagaacag
    46381 tgtaagcaaa caaagttgtt agaagtacag gtttcaccca gacatgcgtg tagagtacaa
    46441 acctataaat agtgaatgcg tatggatgtt tggatcacga agtatccgaa acaagaagta
    46501 atgcgatacg taacaattga ataacgtaaa cgtctgaaaa ttgaatagga acaagagatg
    46561 tttcaaatgt tgaagatgta acgaaaacaa aatttttgtt taacatgaag aaattcaaca
    46621 ccgtgctttg catgtatgat ggaaagttac aatcatttct gtttatttga atccttccga
    46681 ggtacaagaa agccgagctt atcgagagct cggctttttc tttgtcataa aatctttgta
    46741 aagctttttt gttattcaaa actagcggct tttcataacc ttatttcacg aacatcgcat
    46801 ctccaaaact aaagaaacga tagcgctctt caatcgcatg ctggtaagca gataaagtca
    46861 attctcttcc tgcaaaggca ctaactaaca tgactaaagt cgattttggc aaatggaaat
    46921 tagttgagaa agcttctacc actttgaatt catagccagg cgtaatgaaa atatcagtcc
    46981 atccgctgtc tgctttgatt tctccattaa atttcgttcc aatcgtttct aatgttcgaa
    47041 ttgaagttgt tccgacagcc acgattttcc cgccattttt acgtacttgg ttcaatcgct
    47101 cagccgcttc ttccgtcaaa cggtagaatt cactatgcat atggtgttct tcaattttat
    47161 ctacgctgac aggtcggaat gtacctaacc ctacatgtag tgtcagatag actaattcaa
    47221 caccctttgc ttcgatctca tcaagtaatt ctttcgtaaa atgcaatcca gctgttggcg
    47281 ctgcagcaga accattttct ttcgcataga cagtttgata gcgatctggg tcttccagac
    47341 gttctttgat atatggaggc aatggcattt ctcccaatga ttcaagaatc tctagaaaaa
    47401 ttccttcata ctcaaagtca atgatccgtc cgccgtgttc caattcttct ttcactactg
    47461 cttgcaatct gccatcacca aaagagattc ttgtcccaac tttggcacgt ttcgcaggtt
    47521 tgatcaatgt ctcccacgta tctccttgtg tattcgttag aagaaggact tctaaatgcg
    47581 caccagtatc tggtttttct ccatataaac gagcaggcag aactcgtgta ttattcataa
    47641 ctagcgcatc accaggctgt aactcttcaa tgatttcatg gaaatgttta tcttccatct
    47701 ctccagtttt ccgatccaaa acaagtaaac gagaatgatc gcggtctttt aatggtgttt
    47761 gtgcgattaa ttcttccggc aagtcaaaat caaaatcttc tgttgttaac atatcgtcac
    47821 tcactttcta tcatgtgctt catcattcta tcatgttttt cgttctgttg gcaaaatcag
    47881 cactttttca cttctatttt ttgttttcct aaataaaaaa actaccctat ttgtattttt
    47941 tcattgtttt aggcatacta gtaatagata gttcttcatt gaaaatagaa aaagaggtgg
    48001 caccatgatt gaatttcaaa atgtgtcaaa aatttataaa ggtggaaaag tcgctgtaga
    48061 ggacgtcaat ctttcatttg aaaagggtga gttcatttgt tttatcggta cgagcggaag
    48121 cggaaaaacg acgacgatgc ggatgatcaa ccgaatgact gatccaacac aagggaaaat
    48181 tttgattgat ggaaaatcca tccaagaaat tgatccagtg gaattgcgac gtcagatcgg
    48241 ctatgttatc caaagtattg gattgatgcc tcacatgacg atccgtgaaa atatcactct
    48301 tgtccaaaaa ttgttgaaag tcagtcaaga agaacggaat aaaacagctg aaaaaatgat
    48361 tgatcttgtg gaattgcccc gtgagatgtt agatcgctac ccacatgaat tatctggtgg
    48421 tcagcagcag cgtattggag tcgttcgtgc ccttgcagcg aatcaagata tcatcttgat
    48481 ggacgagcca ttcggtgcgc ttgatccaat cactcgtgat tccttgcaag accttgtcaa
    48541 agatttacaa gagcgtttgg gaaaaacgat cgtatttgta acccatgaca tggatgaagc
    48601 gattaaacta gcaagccgta tcgccatcat gagtgaaggc cgtgtgatcc aatttgatac
    48661 accagaaaat attttacgtc atcctgcaaa cgatttcgta gaagagttga ttggagaaga
    48721 tcgcctacta caagccaagc caaatgcgac aagagtcggc gaagttatgc taaatacagc
    48781 aatcacgatt acaccggaaa aatcattaca agaagcaatc aaactgatga gggaaaaacg
    48841 tgtagatacg ttgttagtta ccgataattc gaatgtatta aaaggattta tcgatgtaga
    48901 aacgttgaat aaaaaacgag gaaaagtatc cagtgtcggc gacattttga ataaacatgt
    48961 tttttacgta aaagaatccg cctatcttcg tgataccttg caacgcattt taaaacgcgg
    49021 gctgaaatac gtgccggtcg ttgatgaaca gaacaaagtc gtaggtatcc tgactcgtgc
    49081 atcattagtg gatatcgtct acgatgtgat ttggggagaa gatcccgcaa ctactgatgt
    49141 tgcagagtca gctactcctg aagaatctaa ggaggtctga cctatgcagc agttttttca
    49201 tcagcacggt tcagaaattc tctcaaaagg ttttgaacat ctttatattt caggacttgc
    49261 tttgatcatt ggtatcatca ttgctgtacc gcttggtgtc ttactgacac gttttccaaa
    49321 agctgccacg attgtgattg gcttaaccag tgccttgcag acaatccctt ctcttgcttt
    49381 attggcattg atgatcccgc tatttggcgt aggtaaatta cctgcgatta tcgcactctt
    49441 tatttattca ttattgccga ttttacgtaa tacgtacatt gggatgaaaa atgtcgattg
    49501 gaattatcgg gatgtggcaa aaggcatggg gatgactgag ttccaatcca ttttttccgt
    49561 tgaattgccc attgctatgc caacgatcat ggctggtatt cgtttagctg ccgtttacgt
    49621 gattgcatgg gctacacttg cctcttatat cggcgctggt ggtttaggcg atttgatttt
    49681 tagtggactg aataattacc aaccagatct cattttggca ggtacgatcc ctgtaacaat
    49741 tttagcacta ttggctgatt ggcttctagg tctcttggaa caccggctga caccgatcgc
    49801 acttagagag gagaatgaag aatgaaacgt atactaaaaa tgaccatggt tcttttctct
    49861 cttcttatac ttgcgagttg ttccttccct ggtcttgcca gcaatacaga tgaagacacc
    49921 atttcgatca caggtggaat cacttcagaa gcacagatct tagcaagtct agttgccgga
    49981 atggttgaac attatacaga taaaaatacc gcaatcatca acaatctggc tactacaact
    50041 atcaaccatc aagcgatgat gaacggagat gcttcaattt cagcggctcg ctacacagga
    50101 acagatttaa cgactacatt gaaccttcct cctgaaaaag atccgaaaaa agcgtttgct
    50161 accgtgaaag atgaatttga gaaaagatac ggtcaaacgt ggttcccgtc ctatagtttt
    50221 gaaaatacgt atgtctttct tgttcgaaaa gacaccgcac aaaaatacca tctatctaaa
    50281 gtcagcgatc tgaaaaatgt agcggatgaa ttagtagctg gtgtagatac ttcttggatc
    50341 aatcgtaaag gagacggtta tgacggcttc caagaaactt atggcttctc cttcaattcg
    50401 atattaccta tgcagattgg acttgtttat gacgcagtcg aagcaggaaa aatggatatt
    50461 gttcttggct actctacgga tggacggatc gccagttatg atctagtcat gttggaagat
    50521 gatcgtcaat tcttcccacc atatgatgct gctccagttg tagacaacaa gatattagct
    50581 gatacgcctc atttaaaaga agccttaaat aagttaggtc ataccatcag tacggaaaaa
    50641 atgcaggaat tgaactacga agcagataat aatctagtgg aaccatcagt agtagcacaa
    50701 cgtttcttac aagaaaacca ctattttgaa gggaagtgaa gcaattggat aaaatgaatg
    50761 tctttcaaca atttttctat tatttccagg aaaatggctc ctatatcttt gcacaattta
    50821 tccgtcactt cctgatttct atctatggtg tcctctttgc agcagttgtc gggattccgg
    50881 ttgggatcat gatttctagg agacgtaaat tagcaaactg ggtgattcgt ttggcgaata
    50941 tcatccagac gatcccttct ctagccatga tctccatttt aatcattgga ttaggcctgg
    51001 gagtcaatgt cgtgattgtt actgtatttt tgtattccct cttaccgatc atcaagaata
    51061 cgtataccgg gatgatccaa gtagacaaaa acatccttga tgtcggcaaa ggcatgggga
    51121 tgactgctag acaacgacta ttcatggtag agttaccact ctctgtttct gttatcatgg
    51181 caggcataag aaacgcgtta gttgttgcca tcgggataac cgcgatcggt gcattcgtcg
    51241 gtgctggtgg tcttggagat atcattatcc gaggaaccaa tgcaacagag ggcacatcga
    51301 ttattttagc aggtgcattg ccaactgcat taatggcgat catcacggac tggcttttag
    51361 gtattttgga aagacggcta gatccagcca gccgtacatc acgctgatgt tattgtaaaa
    51421 aacaaaagct tctgcgacca tttgttggtc gcaaaggctt ttttagttct gtcattttta
    51481 aggcaataat ccactctgat tcttccctcc ttatgggcaa agagttgctt ttcttagcta
    51541 tttatccatt ccgtatactc caacttcata ctgccaacgg gttcatatct gcatccaccg
    51601 actaagtttt tttcttatcc gctaaggcat tttgccaatc cattttccca tcactcgtca
    51661 tggaattcat accacatgat ctctaaatac tcgtctgctt gttctttgaa ttgggcatca
    51721 attcttacat cctttggcgt ggctttcatt taagcctttt ccatcagtcc tcgattgttc
    51781 gatgccttca gctgcatcat caaaactggt gactgccgta tcggtaactt cgatcatctt
    51841 ttatacaatc gggaacttgc catcctcatc cttggctaaa aacatatcta gccattccag
    51901 cttctcgcca tgggaggttt gcggttccta aaaccggtac acgattctta tggactgcat
    51961 ccgtcgcaac tagacttggc gatacgatga tccttcacca gaagagcacc cccgtaaacc
    52021 aattgatcga tatattgcca ataagaaaag acattggcgt aaaagatatc gatccctcgt
    52081 gatgcattgc cgttgatact gctattcatg gccgaaagcg ccacgacttt aacttcttcc
    52141 gtttgagtga cattcatgtt cggcaatgtc gctttggata cccgctctgc taaaggaacg
    52201 acactggtat tgtatttcgt atctgtatct tttccaaaag accatgccaa cgaatcctct
    52261 gggaaccaat aagacgactc cggttgattg tccattgctt ttttcaacat acttttggct
    52321 gtttctcgat aaacgacatt tccaattgtc ttcgcctcac tttggcgata atcgatggtc
    52381 gttgccactg ccaacactaa caacgatgct ccaattttac tgattttcct tgtcacactt
    52441 cttcctcctt gttttacata aacccgtcaa cattccattc ctaaactcaa acaatgaccc
    52501 ttcaaaggtg gagatatagg aacaaattaa agaaatcatg caataaatcc aagaaggttg
    52561 gttttagaac aaaaaaagag tctccttttt ggggagactc tttgttaact atctaaaaag
    52621 gttggctctt ctcacttcac tcataatgtg tccaggcaga ataaatttct acaactttat
    52681 tttcctcatc aactttgtaa accactcgat gctgtctatt cagcctgcgt gagtatctgc
    52741 cttcatgtgt aggtctcagc ttttcaaaag actgcgtggg catatatgga tcttccttca
    52801 atgtctgaat cacttcttca aattgtttct ttaaattcgt ttgcttgatt tttcttaaat
    52861 ccactttcgc agagtttttg attgcgactg tatagttact catcaaagag cttcccaatc
    52921 aatatcatcg atattcgtaa agctactgtc gtctttttcg cggtctcgta ctttatctaa
    52981 agtacctgtt tgctcaagaa aaagggtttc ttgaatcgct ctccagtctt ccagcccaat
    53041 caatacagca ttgtttccac tacgatcact aataatctcg atttcagtat gattttcatt
    53101 tacctctttc aataactgat aaaaattttt acgagcagtg ctaggattca tcgttgtatt
    53161 agccattgtc tctcctcctt tttctgatat aattatagcg tacttgatta agtacgtcaa
    53221 aaaaatacaa taaagcactt aaattcagca aacttttcct cttttttaca tagagaaaaa
    53281 gacccctttt tagggaggat ctttgtccac gctcacttct tactccttta cgactagcgg
    53341 tagccaaacg taaagtaatt ggtaacaacg tatcatcttt agcaaaggtc gaatccaaag
    53401 cctgtgagtc tatgcaacaa caccaataca cgaaggttcc tcgttgcagt gtgacttgat
    53461 tgatatcttg aataacctga ggatacgcac gaaagatttg taacggttat tcaaaactga
    53521 ttttggccgt caagtcttct actgcctcaa aaatgattgc ctctttcgtc tcctgtcatt
    53581 catgttcact atcgatttga tacttgctta gaccgttggg tttgtgaatc accaattaaa
    53641 aatggcactg agttatggta acaaaaaatg gtcacttgac gaggctgaga ttcctactta
    53701 tgaagacaca tggcacttaa gagtcgaggt aaaggaagaa gctgaaaata taggaggctg
    53761 tacattattt ggcaaaggat tcggaaatta tgatcaagac atcaaaatca aaatgtttta
    53821 cagctaaata ggaagaataa taacatttca tacgctgttc ccatctttaa tggcttatag
    53881 agggcacctt tagctgagaa taagacaaaa cagaccctct agcttcaatt aagagctaga
    53941 gggtctgttt ttgattttaa aacttggttt atttcttcaa atggtagcta taggtgctga
    54001 caacgatatt ttcacgccaa gacaatcgca atcttaaccg caaacttgtt tggttatgga
    54061 gaatattctg ccagcgtctg tttggtacaa attgaggaat caacacagta gttgtatagt
    54121 tttgtttcgc tgcattttta cttacgatat ctacataacg gataattgga ttttcaatcg
    54181 agcgataaga agagtggacg attgaaaaac ggacatctgg gaaatgcttt ttaaattctg
    54241 cttcgatttc tttttctttt tcgacatctt cgtctagcga aacatgcatc gcaacgacat
    54301 aatcaccgat cgaacgtgcg taattcaacg caccgatatt tacccgtgtc acattcccga
    54361 ctaatacaag aacggtattc ccgtcataat catgtagttt tgcatcattt tctaaacgaa
    54421 gctgttctgc tactttttta taatgatcat ggatcttata aaaaatgaac ataacgattg
    54481 gcataatgat gaagaaaggc caaatgtccc ctaaccgata gacaaacaaa atcgcaatga
    54541 ttgcatatga gatgaacgca cccgtaatat tggcaatcga tttgcttaac catctttttc
    54601 cttctttttt ccatttgacg accatccctg tttgagataa agcaaatgga atgaacacgc
    54661 cgatagagta taacggaatc aagcgttctg ttgagccatg gaaaataaac agcaatacga
    54721 tcgaacctag cgctagtgtg ataatcccat tggaatagcc tagtcgatcc ccacgatctt
    54781 gatacatgtg aggcatgaat ttatcttttg ccagattgta tgcaagaact ggaaaagcag
    54841 aaaaaccggt gttagcagca actgctaaaa tcagcgctgt agcaaattga aggacgtaat
    54901 acaaaatacc atgtccaaag acagctttac caatttgaga caaaacagtg acttcttttt
    54961 caggaacgat cccataccaa tagttgataa atgtgatccc cacgaagaag aaacctaaga
    55021 tcaatgccat catcgtcaat gtagcagcgg cattttttgc tcttggcttc ttaaagaatg
    55081 gtacagcatt actaatcgcc tccaccccag ttaaagagga agaaccagaa gaaaatgctc
    55141 gtaaaatcaa agcgatagaa acacccggca cagccgctcc tggaagtgca gtagcttgca
    55201 atggcacagc acctgtcacg atattatata aaccaacaac gatcagtaac gagatcacaa
    55261 ggataaatgt gtacaccgga aataatagga acgatgcaga ttccctcagc ccacgaagat
    55321 tcagcatcat cagtagcaaa acgattgtca cagaaatagc gacttgatga ccgtagagtg
    55381 ctggcaccgc tgatgtgatc gcttcagcac ctgctgagac agatactgct actgtcaaca
    55441 tgtagtcgat caataaagag ccaccggaaa tcaagccagc attctttcca agattctcac
    55501 tgctgacgac atatgctccc ccgccatgag gataagcatg gatgatttga cgatatgata
    55561 gcgttaatga aatcaataaa ataataacaa aagcggcaat gggtagcgaa taccagatgg
    55621 ctgcagcaga caaagcgact aaaacgacaa cgatttgttc cgtaccatat gcaatagatg
    55681 ataacgcatc agacgacaat aatgccaaag cagcaaatcg ggttaatttg tgctcatcat
    55741 tttcagcaga ttttaaaggc ttacctacta acaacctttt taagtaatcc aatttctaaa
    55801 ctcctttaca cacaatttta cttcaagttt tatagtcgaa aatttatagt aaacaagatg
    55861 ttatagtacg ctcactgacc ttaaaagtca ataaacttta agaaaataat tggaaaaaaa
    55921 cagaaaaata tcaagcgctt tttcaaacgc tttaatacag caaaaatcta acattttttt
    55981 atgggctttt tctttgaatt ctataataaa aggatagaac ttgacttaga aaatcaagtt
    56041 ctatcctttt tgatatctta acttttggaa gagagatgta aggctgcttt ctacccatca
    56101 ttcttactac tcgaagcata gcgcagttgt cacaacctct tgataaacgg tgtttaaaag
    56161 cttgcatctg cggtaataag cccaaccaaa ttaaaaacat aagaagctgt ttttatttgg
    56221 tcgttcttat tacttgatgc agagcagctt ttttacaacc tcttggtaca cggtgttcaa
    56281 tcagctgacc ctcggtatta gctcaaaaaa acggcaaaat atgaggaact atttttccat
    56341 ttttttctct aatactcagg tcaaaacact gatttcacaa cctctttttt taatgaaaaa
    56401 tatggctctc atgcgccgct tctttgaatt tcgtcatttt ttcttcgatg aacggataga
    56461 ttgccgttcc tacgattcca aagacaacaa acaaaccgat catgatccag attgctttcg
    56521 tagcatttgg ccaataaatt cctcctgcag attcccgtaa caagtttacc gcatgagtaa
    56581 atggcaagaa cggattgatc atttggaaga atttccctga gacttggatc ggatagttcc
    56641 cgcctccgcc agagatcgac agtactaaga tgataatagc gatcccttta ccgacattat
    56701 cgaataatgc agccaagaca tagacgatca tcatgaacgc taaggcgatc aagacagcaa
    56761 atgacacgct gtagaccgga ttttggacat ctactcctag taagaaaata ttccctaatg
    56821 taacgatcaa gctttgcgca atcgccattg tcaaaaatgt cagcatacga gcaacgaatt
    56881 gttctcgttt cgtaaaattg tttcggtctt tctttcctaa atagtattct gtcgtagcaa
    56941 cacttgaaag aagaacagcg ccgacccaca gacatagtgc agtataaaac ggggtgctag
    57001 ctgaaccgtt atttgcgatt ggataaagcg cattggtttg tagctcaaca ggttgtgtaa
    57061 agaagtcact ttcttttgtt gcgtctagtt tcaataattt gatgacttcg cctagatcga
    57121 cttcttgttc gccttttcgg atcgcgtctg ctgctttttg gataccagct ttgatatttg
    57181 gccagtcatt gttgatcaag tccgcagcag cgttcacagc tgtttcgact tctggcattt
    57241 tttcatttac tgttgtcaat gtaccggtga tttcattttt tagtgctggc caatcatttt
    57301 ggataaaatc agcggccaat cctaattttt gctgaatgat cggtaattca ttgttgtata
    57361 ggtctgcccc ttcattgatg ccattgacga tggtatccat atttccattc agcattgtat
    57421 tggcatcatg gatttcttgt ccaattgcag gcatttcttt ttgatatttt tctaaaattg
    57481 ccactgcatt cgttacagtt gctttcgttg agctgagaag cgaatcaaag tcgatctggt
    57541 ccgctttgct cagtgcgcct tgtgcagtcc caatcgtatc gatgacttgg tctagtagag
    57601 aagtgacagt ggaactgatt tgacctgtat tgataccagc aatgatgcca ttgatattat
    57661 taacaacggc atcaatttga tctagcaatt catcaatagc cttcgtgtct tcattttgaa
    57721 cagctgtgtt caaagcagat aggcggtttt gcagattgct tagcaagggt tttaattgat
    57781 ttagctgatc aataattggc tgtaatttcg tatttccagc acttgtttgc aatttagtca
    57841 ggaactcgac cagtttatcg attgcatttt gttgttgaga tattccgtca ataaagccgt
    57901 tcaatacatt gctgatgttt ttcttttcat catcagtcag cttaccatct tcaatagctg
    57961 ttcttacagt atctattaac gaacctgtcg ttgttgccac ttgtccaatt gacttcaatg
    58021 taacatctac actgtttgtg atgcttggta tcgcatcttt cagctgagag gcacctgatt
    58081 ttgtttggtt tgctagatca cttgcctgat tttctaaatt tttcacatct ggcaagatat
    58141 cttgtacttg ttggatgatc gtcaagcctt gttttgcttc atcgattcct tggttcattg
    58201 tctcttggat cgaagcaaaa tcgccgtcga tctctgctag ttgcttaccg gcattttgga
    58261 tctctgggat tttttcttgc aaatcaagga tgatttttgc ttgatctttc aactcaggca
    58321 ttttgtcatt caatgcaacg actttttcac ccatctcatc tactttaggg atgtaatcca
    58381 cgaattcatt tgctttattc agtttttcct tgatttcagg tagttgactt tgtaattcga
    58441 ggacttgttt tgtgtagccg tcgatcgtgt ccaaattttc atctgttgat aaaatcatat
    58501 ctttaacttt attgatactt actaggttcg tatcgatgtc gtaacctatc tcattgaata
    58561 ctttcaataa agtcgaactg gctgttttga taaattcatt tgtgatttgc gattggatcg
    58621 aacttgctcc tttatcggtg attttcggtg caatcgcatt gattttttca tttaccgtat
    58681 attcgatttt tggtttcttg atatcaccac tagtaaaact cagcagatct tctgagaaat
    58741 cctttggcaa gtaaatacct gcgtaatact ttccggaacg gactccgtct tctaattgtt
    58801 cttttgaatc aacgaattgc catcctaatt gtttattttt atgaagcgat tcgatgactt
    58861 gctccccaat ggccacttct ttaccttgaa actctgctgg cttgtctgca ctgtaaacag
    58921 caattggcag ctctccagta tttccatatg gatcccataa tgctttgatg ttaaaccacg
    58981 catatagcga agggatgatc atgatcgcga tgatcagaag tgttgcaatc gggtttttga
    59041 aaatccgttt ccagtcaagc aaatataatc gaagcgtatt tttgattgac tgcatagttc
    59101 tcccccttct tcttttttca gctgaattac tttaccatgt atttcatact tttttcaatc
    59161 ggcttttttc aaaaaagtcg aatttttgga catatcacgg caattgtctc attgtaatct
    59221 cttacatatt gagaaataat taaggattac agcctttact ttatcatgaa ataaaaggga
    59281 aagataattt tatgccaaag tttttatcta ttatacgtat acgcaaaaaa gctaaaacat
    59341 tttttgtctt tgcccctaca aaaatgtttc agcttttttc gttttttatt cctgtatttc
    59401 ttatttttcg aatgacagga tgattttccc agcaggagga tgtccttcaa ctagctgatg
    59461 tgcttggatg acatgcttaa gtgaagcaga cagattcatt gaaataaaaa catgaaaggc
    59521 tcctttttgg taggctttga ttatgccagc aaaggcttct gcatctagat attcctttct
    59581 tggaacaaac gattcataaa agccttcctt tttttgccgc aaatctagat ctgggaggtc
    59641 atttaatgca acatacctgc cgcctggttt catgatctgg atgccggttt ctcctttgat
    59701 acttcctttc gtcgcatcga ttacaaggtc tgcctgatca gcaaattgca gacctggatt
    59761 tgttttatca taagcagcaa atgctgaagc tcctaatttt tttacctttt cctcattttt
    59821 actggatgca ctggttaaga ttcggattcc cttttcatgg agaagctgga tcagacttga
    59881 cccgaccgca cctgatgctc ctagtatcat tacagtatct gtcggctgga tttccgtcaa
    59941 atggttgatt agattataag ccgtaattcc tggcgtgacc attccggctg cttcttccca
    60001 actcatttta tctggaattt ttgctacttt tgctgatggc aacacgactt cttctccgta
    60061 agtcccgccg actgcatgga cagctactcg atcacctaca tgaacagttg tgacatctga
    60121 accaatctct gtcacaatac cagcgccatc attacctggt acataaggga atttcaatgt
    60181 tcgtatctct ttcatttctc ctaaacgcaa ggcaacatca taaggattca cactgaatgc
    60241 ttttatttct acacgaacat gtccagaacc gacttctctg ggatgagcat cgatttcttc
    60301 aaaaacatct tgtgcttctc cgtaaccgtt aattgcaaat cttcgcatgg tcaccatctc
    60361 cctttttctt taagtttacg tttatgcctt tattttgaca aaaaaaatgt cttttcgttt
    60421 tggcgcatga ttcaaaacaa aatagttgtc ttttttcgcg taacgtgtta aattatttat
    60481 ctaaaagcgt aaagattacg atttacgcta ataaaaaata attggaggaa tttgttgatg
    60541 gctaaaaaat caaagattgc caaagcaaaa aaacagcaag aaacgattga acgctatgct
    60601 gctttacgcc aggaattaaa agcgcaaaaa gattacgaag gcttgcgtaa acttccttta
    60661 gatgctcgtc cagaacgatt gaaaaatcgt gatttaatcg atggacgccc tcgcggatac
    60721 atgcgtaaat tcgggatgtc ccgtataaaa ttccgtgaat tagcacataa aggtttgatt
    60781 ccaggagtaa aaaaagccag ctggtaatcc aagtctggct gtaatgtaaa ggaggagggc
    60841 gcatggacca ctccttggat catcaaaaaa gatacgttcg cttcttctag cagaaatgct
    60901 ggtactagaa gcagacgtat ctttttttac gcacagctgg tcctttttta tatgtaaagg
    60961 ctgcatggtt acttcgctat atttatttag taacaggagt cagtgcttcg atacccacac
    61021 taattttcaa tgctcggtca acttctgcca taatgggtcg atccaaatgg cagacctttt
    61081 ctttcaatct tgatttatcg atcgttctga tctgctccaa caggataacg gagtctcttt
    61141 ctattcctgt tccagtagct ttgatcccaa tgtgagtcgg aagcttaggt ttagccattt
    61201 ttgccgttat ggccgcaaca atgatcgtcg ggctaaaatg gttacctaga ttattttgaa
    61261 taaccaaaac tgggcgtgtt ccgccttgct ccgatcccac gactggagaa agatcagcaa
    61321 aataaatatc tcctcttttt accataggat cctccttatt cttgatattc tcttggtatc
    61381 cgctgtccta atccgcaagc cacttcatag tggatcgtac ctaattgatc tgctatatcc
    61441 tgcatagtga tttctttgtc tgcatttttg ccgataagcg tcacttttgt tccgacagga
    61501 aattcttgag gcaatcggat catcagttga tccatacata cacgcccaat cgtttcacag
    61561 tagttccctt ctaccaatag agaaaaaccc tgcatctttc gtggccagcc atctgcataa
    61621 ccgatcggta tcgttccgat ccactctgct tcaggagtga tatatgtttc tccatagccg
    61681 attccttcac ctgctgggag ttttttgact tgaatcaatt cagaaaccag ctcaagtgct
    61741 ggctgcaatg gataaacttc cggtagtgcg tgcccagagg gattaagtcc gtacattgct
    61801 actccataac gaatcatatt gccgattgtt tcatcatgcc ataaagccgt tgcactattg
    61861 ctgacatgta catatcgagg aagttcggga agttttttca gcacttctat aaagcgttct
    61921 ttttgcagat tccaatatgt atcatctgcc tgatctgctg tagaaaaatg ggtaaataaa
    61981 ccttcccatt ctaatacacg actttctttg atgaatgcag ctgcctcttt tacttcttca
    62041 ggtgtacaaa atccgatacg acccatccca gtgtctgctt ttagatgaat cgaaagaggc
    62101 gtctctagct tacttttctc taaaacagca gctgctgctt gcaaccattc ccgtgtacct
    62161 gcagttactg ataaatcatg agcaacagct acagtcagtg cgtcgtaagg aaccatattc
    62221 aagataagga tgggctgagt aaatccagct tctctcaact cgactccttc atctaaattt
    62281 gaaacacaaa agcccgaagc tccacctgca actgctgcct cagctgtttc aatagctcca
    62341 tgaccgtatc cgttcgcttt tactactgca aacaattctt ttccttgcgg aagtcttgca
    62401 acttcatttg ctacattttc agttatagct tttttatgta tcactgcttt cgttgggcgg
    62461 tgccaagcga caaccatcgt ttttccttct ttctagtctt ccaaaataat ttgtgcaaaa
    62521 gctgtttcat ttgtatgagt aatactgacc catacattgc cttcatgagg tgaacgcgtc
    62581 acaacaggct gaccattttc attttttaaa atctcgacat cttgaaaggt aacttttccg
    62641 atcccagttc cccaagcttt agagaaagcc tctttgcaag cgtaacgccc gcctaaaaat
    62701 tctacttggc gatgaaaagg caaggactgg aatagtttca tttcatcaga ggtcaagatt
    62761 cgtgcaatga attttggttt ttcttcgatc agccgagtga tcctaggaag ttcgactgca
    62821 tcgatcccaa ttccttttat catatgcttt tctcttttca ataaatttag aacactctca
    62881 ttctaccaaa ttataaccat tttgccacaa ataagtccac aaataacaaa aatgaaagtt
    62941 tctcttaaaa aagagaaact ttcattttat gtttaatcgt tatttgaacg gattacaaat
    63001 ccgcgttttt tatcattgtg acgtttaccg ccatcttttt ggctgttatt atttttgcta
    63061 taaccgcctt ttgatttgtt tccacgataa ttaccgccgt cacgacgatt acggttgttt
    63121 ccgccaccac gtttgccatt tttattgtat ccttttttct gcattggcaa tgggcgttct
    63181 ggtgtgatct tcactggcac tgcatcagct ggatcttttg ctgtcgtttt tagcaaaagt
    63241 gcaactaaat cttgtgcaga atattcttct aataatttat ctgctgtttg caggtattta
    63301 tctagaccat tttctgcaag ttttgtttcg atttgttcaa ctgcagcacc taattgacct
    63361 ttgaatgctt ctttttcggt tggtggacgt aaagtcgtca tccgtttttt cgtcaagttt
    63421 tcaatcacat gcaagtagtc catttcattt ggtgtaacga aagtcacaga cataccgcct
    63481 tttccggcac ggcctgtacg tccgatacgg tgaacgtagc tttctggatc ttgagggata
    63541 tcatagttgt acacatgagt gacacctgaa atatctaatc cacgtgcagc aacgtctgtc
    63601 gctacaagga tatctaaatg accgctctta aatgaacgca atacgctcat tcgtttttgt
    63661 tgagacaaat cgccatggat tccttctgca cggtaaccgc gtgcttctaa tccgcgtgcc
    63721 aattcgtcta cacggcgttt tgtacgtccg aagacgattg ttaattcagg tgtttgaaca
    63781 tcaaacaagc gagtcatgat atcgaatttt tcgtattctt ttgcgcggac atagtattga
    63841 tcgatcaagt cagctgtcat ttctttcgct ttgatcttca catgatgtgg atttttcatg
    63901 aatttaacgc caatattctt gatagctggc ggcatcgttg ctgagaaaag taatgtttgt
    63961 ctttgatcag gaacttgtga aatgattttt tcgatatctt ccaagaagcc catattcaac
    64021 atttcatctg cttcatccaa aactaatgtt tgaacggttc caagtttcaa tgtgtggcgg
    64081 ttaatgtggt caagcatacg tcctggtgta cccacaacga tatgtggacg atctttcaag
    64141 ccacggatct gacggccaat atctgctccg ccgtaaacgg cttgtacacg tacttttttg
    64201 tcgcgcccta aacgatataa ttcttcttgt gtttggatag ctaattcacg tgttggtgcg
    64261 ataactaaac cttgtaattc gtgacgatct ggatcgattt tttctaacat tggtaatcca
    64321 aatgcagctg ttttccctgt acctgtctgt gcttgtccaa taacgtcttt tccagctaat
    64381 gctagtggaa tcgtttctgc ttggataggc gttgcttctt caaaaccagc gcgttcgact
    64441 gatttcaaca attctggtga taattctagt tctttaaatt tcaaatgaat cctcctatat
    64501 ggttgttaac tgaggatgta gcttttttgc taccccgtcg atttgttcgg tcaaagtgta
    64561 ttgtttcttt ttgacagtgg ccacgcacgt ttttatccat tcttagcccc tgtggcacca
    64621 ccgaaaaatc actttgcgaa gtttaggcat tagaaaagcc aaacgggtcg cgttcagctt
    64681 tatcattatt atgacatctg gcttcaacaa gttgtttcta tggcaaaacc agtccaattt
    64741 ctcttcatct ttcggcaata ggttattcta acatagtttt tcgttttctg caagtttaca
    64801 gatttttatt tcatttgctg aagttgttct accacttcaa ataagcccat gctgttgctg
    64861 ccttttagca taatactatc tgttgcttca agattttgtt tgatagcatc aatcaattta
    64921 ttcttttctt tttcaaaata gaacacaggt agttgggggt atttttggtt caattcttct
    64981 tttagtgcat gcatttgttc cccataaagg aaaatcatgg cgaatttctc aggatcgata
    65041 tgttcactca tttgcgcatg catatttaaa gactctttcc ctaattccag catatctgct
    65101 aacacagcga ttctgcgtcc ttttgttggc agatttttaa aagtatctaa taccagtccc
    65161 atggctgttg gatttgcatt gtagacatcg ctcaaaatag ctgcaccatt tcctgccgtt
    65221 agccattcgg ttctgttttg agtgatagaa acatgggcga gcccttggcg tatctcaggt
    65281 atggacagtc caaagaagcg cccgatcgta tacgcaatca aagcattcgt tacattataa
    65341 cttccaggca gcgggatcgt aaatgtttct ccttctacta caaaatcggt ttgtgctttt
    65401 ccttttgctg tcacttccgc atgaacatcg ccatttccaa taccgaatgt tgtgactgtt
    65461 tgtactaatg ttgccgttaa aggtgtcagc aacggttcat ctgcgggcac aacgagtaat
    65521 ccgtctgata caagtccgtc agtgatttcc attttggctt tagcgattcc ttctcgcgac
    65581 ccaagatttt ctatgtgtgc ttcaccgatc attgtgattg ctgcagcttt tggttgagcc
    65641 ataagtgaaa gttccgtgat ttcattggcg tgatccatgc ccatttccaa aacgatcttt
    65701 tctgtatctt ggggcatgtg caaaatcgtg taaggaagac caatattatt gttgtaattt
    65761 ccttgcgtct tatatgtttt gtatttttca gacaagacag acgcggttag atctttcgtg
    65821 gtggttttac cattgcttcc tgtaattgca acgacttctg cgcctacttt ttccaagtaa
    65881 taggttgcca attgctgcat ggctttcaaa ggatctgcta caggaataac tggaaaattt
    65941 tttggagctt gttcaacagg caagctccaa aatgaagcag atgctccgtt tgtgatcgct
    66001 tgctggataa attcatgtcc atctcgcgta ccagcaagag gaacgaataa acttccttcg
    66061 gttatcttcc ggctgtcaaa ttcgacattg gtaatctttg tcagtgcaga gcattcgctg
    66121 cccacggctt gtgcaatttc ttgtattgtt agattcattg agatctctcc taaaaaaggt
    66181 tgtgaaaaaa gcgtttggcc taaacggcgg gttcgcatga ctctcacttc caagtaaatt
    66241 tctctattcg tatttagaag ctagaatgaa cgcggttacg caatcactcc agcctcttct
    66301 ttatttctct ttattcattt ttttcaaaaa aagattgacg ctgatggtat cgattcattc
    66361 ctaactggat cagttcttca atcaaatcac cgtatttcaa gcccatattt tcccataaga
    66421 gtgggtacat actgaactcc gtaaatcctg gcatagagtt taattcattc aggaataatt
    66481 catttttatt tgtcaaaaag aaatcgcacc ggctcaatcc gcttccacct aacatcgtgt
    66541 aagctaactt cgcgtactct tgcgcttttt gataaacttc ttctggcact tcggctggaa
    66601 tctgcatttc gattttatta ttgatatatt ttgcttcata atcatagaat gctacgtctt
    66661 ttacgacttc accaggcaaa gtcgtccgaa cgtcttcatt tcctaataca gcaacttcga
    66721 tttcgcgcgc ttcaattcct tgttcaacga ttgctcgaga atcatactga taggctgttg
    66781 ctaaagcatt ttgcagctct tctcggtttt ctgcttttgt aatgccgaca ctagaaccca
    66841 tattcgccgg tttgacaaac atcggataaa gcaaagaacc ttcacattga tcaaatactt
    66901 ttttaggatt ttctttccat tgattcttaa gtactggtac ataaggaact tgcggcacac
    66961 cagcagcttg taaaatatac ttggtcatga ttttatccat ggcacatgca ctggtcaata
    67021 cgcctgcgcc gacataaggc atattcaatg tctctaagaa gccttggatc gttccatctt
    67081 ccccgtttgg cccatgtaaa actggaaaaa cgatggctcc ttcttctttg atttcgcccg
    67141 gattgatcac ttttcctgta aagccttcct ctgtctgtcc acttgggtcc catgaaagat
    67201 gcaagacatc tttgctggca ggtttttctg ttagtaatgg acctttgacc cattgtcctt
    67261 cttttgtaat aaatacgagt tgaacttggt aataattata ataaatggca tttaaaactg
    67321 aaaatgcgga aagaatggac acttcatgct ctgcgctgcg tccgccatat agtaaagtaa
    67381 tcttcaaaag attgtcctcc tgtattctaa atcgttcagt gatttactct catattttag
    67441 cacaaaacaa aaataaacga ataacttatt tataaaaaaa cgagccagct tctaaaagaa
    67501 cgagcgtcat ttattttttg tcagctagat tatttgtccc gttttttata aaaagttatg
    67561 ataaagaaaa ggagggatga tgatggcgca aacaaatcca cgcagccgct tggcagaaat
    67621 cattcgagtg ttcatcaatt acaatgtagt gccaaacttt gtacagcaaa aaaatcccga
    67681 acaggtaaaa aaagcctttg aagaactagg ccccaccttc atcaagatag gacagatgct
    67741 ttctgttcga gaagatttgc tttcttctgc cttcactcaa acattcaaaa cattacaaga
    67801 tagtgtacct agcgacacat tttcaacggt caaaaagacg atcgaaacag aactttctct
    67861 ttcattatca gatatattcg atgatttttc aaaatcgcct tttgcctctg cttctatggg
    67921 gcaggctcat cgtgccaagc tgaagaacgg tgacgcggta gtcgttaaga tccaacaccc
    67981 taacatcgcc gaagagatcc gacttgatct tcaactattt gaacgagcga tccctttgat
    68041 caaatacatt cctgaaacta gcgtagttga tctaaaaggg gtactccaag aagtaaaacg
    68101 ttccttgatc aatgaaatgg acttcttaaa agaaagtcaa aatggcgaac aattctatca
    68161 aaagaacaat ggctggaaag agatccgcag ccccaagatt tatgacgctt tttgttcgaa
    68221 aaaagtgatc gtgatggaag aaatgtctgg taaaaacttg aatcatttaa tgaacgccga
    68281 aaacaaaact gaaactttta tcactggaat tcaaaacaag cagctgaaac aagaagttgc
    68341 aaagctttta gttgagaact ttatgaaaca ggtgtttgat gatggttttt tccatgctga
    68401 tcctcatcca gggaatctgc tattccatgt actaacaaaa gaagaacaga cacaagctag
    68461 ccgaaaaact gaaacagtcc atgaaaaaga gttcggttcc tttgcttttc gagcctccac
    68521 ttctgcagaa gaccctgttg cgccatatac catcaactac atcgattttg gtatgatggg
    68581 gcatctttct gcaggactta ggcaaaaact cacacaagcc gttttagcgc tgtatacgaa
    68641 agatgcttat cgaatcgaaa aagcggtcct tcgactttgt cagcaagaag gctcgtttga
    68701 tgaaagtcgg ttccaccaag aactgacaag ttttcttgaa cagtattatg attctcctat
    68761 tgatgaaatc aacttgcaag aagtattcac acatgtcgtg acgatttgtc atcaaaataa
    68821 tctgcagttc gatcgtgata tcacgctttt gctgaaagca tttgggacat tagaaggggt
    68881 gatccgcgtc ctcgatcctg aagtttccct catggaagtc gcttcgcctt ttgctcaaca
    68941 ttattttctc actcatctgg atgtagaaga tacattgaaa caaagcggat tagacttatt
    69001 ggaagggatg aaggctgcgc ctaagatccc tcaacagctc caccatctat tagaaatgtg
    69061 gacttcggga caaggaaaag tcaatttgga attgaaaaag caagacaaat tattgagcag
    69121 gatcgaaagt atgatcaatc ggcttgtttt cggtatgatt ttagctgcat tgatcgtagg
    69181 gtcctccctg cttgtccaag cagcacctgt agaaaacgca gaggtcgttt ccttattagg
    69241 gatatttacg tatgctattg ccgcattcgt cattattttt ttggcaatcg atgcattgat
    69301 ccaaatgtat aagaagagga aaaagtagaa aaaggttgtg acagaaagaa tcagcttcaa
    69361 gaaataagaa ggggttttac ataaattgtt tctcaaattt ttgtgaaaat tcggcttatt
    69421 tttcgaagag gctacttctg aaacaccgag aataaaaaat gtgaaaaagc tgttctgcac
    69481 ccagtaataa gaacaatcaa aaagggaaca tggaacacat ttatcctgtt tccctgttcc
    69541 ctttttgatg tattcgagca taaataaaat accttcgtta cctactatct tctgtacttg
    69601 gtaaacctta gtcaattgcc ttttttaacg cttgacgaaa agacatatga tctttctccg
    69661 taaagggttt tggacccttt gtccttatgc cagcttttct taactttcca ctatgataac
    69721 gttgttctag aagcgtgccg atattcgctt cgtcaaattc ttttccagag tgatggaaca
    69781 ctcgcacacc cttcggcaat acaagtgaag ctaaaccata atcttgcgtg atcaaaaagt
    69841 cattcttctt aaccataccg acgattttat aatccgcact atcagctccg cggtctacgt
    69901 agacgatttg gacatgatta gcgtattctt tggtcgtata atggtccaca ctggtcacga
    69961 taaccacgtc aagaccatag gattctccta attttatgac atcttctttt actggagaac
    70021 catctccatc aatgaatagc ctcattcttt ttcgccttct tccataaatg ataaacagtt
    70081 actaatccgc tcagtaaaag accaacattg atccattttg ccaagataag cagttgtaca
    70141 ctttctatcg gcactgattc atggttcagc gtgatcaata atagatggat tggctctccc
    70201 atttcttttg ctaaaacaaa caaaagcgtc atcaataaaa actggtggat cacactccct
    70261 ttattttgag tagtatactt gacaacgatc cggcgatcca ttggaatagc tgtatcagtt
    70321 tgataatatt ccttatttag ccagctgcct gttactacgt gccagaaact aagcagaaag
    70381 acacctatcg caaaaccatt tggaatcaag aggaccaata aagaagaact cagtccaagc
    70441 aattgcatag ccaatggaga ccatgttaaa cgtttcaaaa tccatggtcc gactattttt
    70501 gctgcaatca agcctgctgc ataaggcaaa tacataaaaa tcgaaagttt ttctaatccg
    70561 tacagtatgc caacataaaa actgctaaat aaaaaaagga aattccctag cattccattt
    70621 agaaaagtaa acagatttag ccagcttggc aacttccatt ccttcttctg gtgtcctaaa
    70681 acaaacacga acaagatgaa cagcagcaag aaaccataaa tagcaagatc aaaaagcctt
    70741 tcatcgaata acaatcgggc atttctcaaa agaaacaata agccaaagaa tatcaaaaat
    70801 aaaacaagct ctcgcgtagc taccagattt cttttgatgt ctttgaaatc cagttcgtaa
    70861 cgcggataat gactaaccgt atggtaggcc atgacgtaaa aaagtgtata aatagtaaag
    70921 cttgctgcaa tctgagtcgg tgcaggcaac tcaatcgctt gatacaggag aaatagccag
    70981 atagctgcaa ataagtactt tttcccatcc atattgataa aaccttgcgt cttttcgtga
    71041 aaattgaccg tggtattagc aggtacaagc catgctgcac tcagccctag caaaacactt
    71101 gaaaaataaa ataaaggaaa ataaaatacg cctaatattc caagcaatga accagcacca
    71161 ccaatcagca gagcgatcat cagcaacgtg taactatcta gaccaaatcg tagactgttg
    71221 actaaaaata gtccagtcat ccgaaaggca taaaacagcg taaatggcaa aatcgtcagc
    71281 caattatgcg agtctgttag tcccaaaaat aaaagataag gaataaaaat aaccgtgtta
    71341 cttaagataa agggcgttgt ttgtgtaaaa ttacgcccaa atcgtttgag tttttcgaac
    71401 atgacaatgg ctccttaaac agtcttataa ctaatctgct cttcgatttt agcattaaag
    71461 gggaaataaa ccaattttac agaatatatt cttgtaaaaa aaaatacaga aagaagcata
    71521 agcttctttc tgcattttta cggtacttga ttactcaagc agacaagccc ttctccacaa
    71581 aagtcttgcc cgacacccct gcatccggca ggtgataaag atagaaatca attatcctgt
    71641 gcctccaaaa tcaattagga gctctgtaaa ccagagtcct tctcgacccg tcgcataaat
    71701 ttactttaac acagttccta tgtttatgcg agagcttttt tcattttata atcgaccatt
    71761 tgaaatcctt gaccgatatc tgaaataagt tcttctgtaa tctcaaatcc ttcatgctta
    71821 taaacctcga ttgcttgatg attcccctga ttcactcgca aaaagatctc tctttccttt
    71881 gtttgcgcag caagttcttc ataccagcga aaaactgaag aagtcaatcc ttgaccacgt
    71941 actttattta gcaaatataa tttacttaaa taaatttttc catttatctc ttcataagca
    72001 gtgtaaccga cagtcttttc ttcgcttttt aataaaaagt aggacacacc ttctgtcagt
    72061 tctttttgaa tctgtttttt tgactgataa gttttcagca tgtaatccac ttgtttttga
    72121 ccaatgatcg gcacaaaaac ttccggccat acttcttgta tgactgccat cagctcatcc
    72181 agttcatttt ctgttacttt tattttttcc atacacccac gtcctttttt acattataaa
    72241 tgaccttgcg cttgatggaa taaaaagagc atgatcatgc tatacacacc caccgaccac
    72301 ggtttcaaga aaatcacaat ctgcataaat tccctaaaag ataatttcgt caaaccagct
    72361 actagacaga tcaagtcgtc tggcgcaaag ggaagcagca aggtaacaac tagtactttt
    72421 ttaatatctt tcgtttttct tgtcagcaat tcatcaaatt tctgatactt ttttggcgat
    72481 aaaataagct ggacaaaggc tacgccatag taacggacaa gcaaaaatcc gattgcttcc
    72541 ccaatcacta ggccaataca actatataaa agcccaaatc cattgccaaa catcagcatg
    72601 cccgctactg aggagatccc tcccggcaaa ataggaatga tcacttggat cacttgcaac
    72661 agaacaaata tcatcactgc atacttgcca aattgctgga taaacgcttg caaagacgtg
    72721 ctcgatcgaa aaatcccatg atgataagca taaagaatca acacaaagaa aaaaaacaga
    72781 ccaataatgg gcatgatctg aagacatttt tgtaaaactg atcctttttt agacatctat
    72841 attccccaca tcttttttca tttattaaaa ctgcctcct
//
LOCUS       DAFLWZ010000004        65647 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000004 DAFLWZ010000000
VERSION     DAFLWZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.004"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            476..1339
                     /locus_tag="L1V38_000261"
     CDS             476..1339
                     /locus_tag="L1V38_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1314843.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="L1V38_000262"
     CDS             complement(1468..3090)
                     /locus_tag="L1V38_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1314844.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="L1V38_000263"
     CDS             3339..3860
                     /locus_tag="L1V38_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1314845.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V38_000264"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V38_000264"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBN1314846.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="L1V38_000265"
     CDS             5941..6759
                     /locus_tag="L1V38_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBN1314847.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="L1V38_000266"
     CDS             complement(6862..7059)
                     /locus_tag="L1V38_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314848.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="L1V38_000267"
     CDS             7228..7806
                     /locus_tag="L1V38_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1314849.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="L1V38_000268"
     CDS             7901..8038
                     /locus_tag="L1V38_000268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314850.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="L1V38_000269"
     CDS             complement(8851..9354)
                     /locus_tag="L1V38_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1314851.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="L1V38_000270"
     CDS             9713..10738
                     /locus_tag="L1V38_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1314852.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="L1V38_000271"
                     /pseudo
     CDS             11061..11939
                     /locus_tag="L1V38_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            12415..12531
                     /locus_tag="L1V38_000272"
     CDS             12415..12531
                     /locus_tag="L1V38_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1314853.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="L1V38_000273"
     CDS             13459..13797
                     /locus_tag="L1V38_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314854.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="L1V38_000274"
     CDS             13891..14121
                     /locus_tag="L1V38_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314855.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="L1V38_000275"
     CDS             14521..14892
                     /locus_tag="L1V38_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1314856.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="L1V38_000276"
     CDS             complement(15166..15858)
                     /locus_tag="L1V38_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1314857.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="L1V38_000277"
     CDS             complement(15861..16646)
                     /locus_tag="L1V38_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1314858.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="L1V38_000278"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="L1V38_000278"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1314859.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="L1V38_000279"
     CDS             18308..18625
                     /locus_tag="L1V38_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1314860.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="L1V38_000280"
     CDS             18638..20311
                     /locus_tag="L1V38_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1314861.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="L1V38_000281"
     CDS             20325..21956
                     /locus_tag="L1V38_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBN1314862.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="L1V38_000282"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="L1V38_000282"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1314863.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /locus_tag="L1V38_000283"
     CDS             complement(24071..24994)
                     /locus_tag="L1V38_000283"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBN1314864.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="L1V38_000284"
     CDS             25190..25795
                     /locus_tag="L1V38_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1314865.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="L1V38_000285"
     CDS             26103..27119
                     /locus_tag="L1V38_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1314866.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="L1V38_000286"
     CDS             27260..28561
                     /locus_tag="L1V38_000286"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBN1314867.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="L1V38_000287"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="L1V38_000287"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBN1314868.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="L1V38_000288"
     CDS             29290..29688
                     /locus_tag="L1V38_000288"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBN1314869.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="L1V38_000289"
     CDS             29754..30836
                     /locus_tag="L1V38_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1314870.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="L1V38_000290"
     CDS             31048..32610
                     /locus_tag="L1V38_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314871.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="L1V38_000291"
     CDS             32603..33736
                     /locus_tag="L1V38_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314872.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="L1V38_000292"
     CDS             33736..34692
                     /locus_tag="L1V38_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314873.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="L1V38_000293"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="L1V38_000293"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBN1314874.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="L1V38_000294"
     CDS             35981..36799
                     /locus_tag="L1V38_000294"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1314875.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="L1V38_000295"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="L1V38_000295"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1314876.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="L1V38_000296"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="L1V38_000296"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1314877.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="L1V38_000297"
     CDS             complement(38679..39260)
                     /locus_tag="L1V38_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1314878.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="L1V38_000298"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="L1V38_000298"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBN1314879.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="L1V38_000299"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="L1V38_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBN1314880.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="L1V38_000300"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="L1V38_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBN1314881.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="L1V38_000301"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="L1V38_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBN1314882.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="L1V38_000302"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="L1V38_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1314883.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="L1V38_000303"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="L1V38_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBN1314884.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="L1V38_000304"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="L1V38_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBN1314885.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="L1V38_000305"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="L1V38_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBN1314886.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="L1V38_000306"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="L1V38_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBN1314887.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="L1V38_000307"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="L1V38_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBN1314888.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="L1V38_000308"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="L1V38_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBN1314889.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="L1V38_000309"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="L1V38_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBN1314890.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="L1V38_000310"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="L1V38_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBN1314891.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="L1V38_000311"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="L1V38_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBN1314892.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="L1V38_000312"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="L1V38_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBN1314893.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="L1V38_000313"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="L1V38_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBN1314894.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="L1V38_000314"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="L1V38_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBN1314895.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="L1V38_000315"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="L1V38_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBN1314896.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="L1V38_000316"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="L1V38_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBN1314897.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="L1V38_000317"
     CDS             51714..51899
                     /locus_tag="L1V38_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBN1314898.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="L1V38_000318"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="L1V38_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBN1314899.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="L1V38_000319"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="L1V38_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBN1314900.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="L1V38_000320"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="L1V38_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBN1314901.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="L1V38_000321"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="L1V38_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBN1314902.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="L1V38_000322"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="L1V38_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBN1314903.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="L1V38_000323"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="L1V38_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBN1314904.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="L1V38_000324"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="L1V38_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBN1314905.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="L1V38_000325"
     CDS             55974..56621
                     /locus_tag="L1V38_000325"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBN1314906.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="L1V38_000326"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="L1V38_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBN1314907.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="L1V38_000327"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="L1V38_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBN1314908.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="L1V38_000328"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="L1V38_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBN1314909.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="L1V38_000329"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="L1V38_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBN1314910.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="L1V38_000330"
     CDS             58059..58997
                     /locus_tag="L1V38_000330"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBN1314911.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEFKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="L1V38_000331"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="L1V38_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBN1314912.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="L1V38_000332"
     CDS             59677..60516
                     /locus_tag="L1V38_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1314913.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="L1V38_000333"
     CDS             60492..61361
                     /locus_tag="L1V38_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1314914.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="L1V38_000334"
     CDS             61351..62148
                     /locus_tag="L1V38_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1314915.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="L1V38_000335"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="L1V38_000335"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1314916.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63762..63999
                     /locus_tag="L1V38_000336"
                     /pseudo
     CDS             63762..63999
                     /locus_tag="L1V38_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="L1V38_000337"
     CDS             complement(64143..64919)
                     /locus_tag="L1V38_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1314917.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..65449
                     /locus_tag="L1V38_000338"
     CDS             65042..65449
                     /locus_tag="L1V38_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBN1314918.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20860 a        11703 c        13838 g        19246 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatagttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgggatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttcttg aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaattta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
    65401 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
    65461 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
    65521 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
    65581 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
    65641 gtatcct
//
LOCUS       DAFLWZ010000005        64393 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000005 DAFLWZ010000000
VERSION     DAFLWZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.005"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..561)
                     /locus_tag="L1V38_000339"
     CDS             complement(<1..561)
                     /locus_tag="L1V38_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1314919.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLK"
     gene            complement(638..1168)
                     /locus_tag="L1V38_000340"
     CDS             complement(638..1168)
                     /locus_tag="L1V38_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBN1314920.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1172..2032)
                     /gene="rlmB"
                     /locus_tag="L1V38_000341"
     CDS             complement(1172..2032)
                     /gene="rlmB"
                     /locus_tag="L1V38_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBN1314921.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2025..2420)
                     /locus_tag="L1V38_000342"
     CDS             complement(2025..2420)
                     /locus_tag="L1V38_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBN1314922.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2417..3829)
                     /locus_tag="L1V38_000343"
     CDS             complement(2417..3829)
                     /locus_tag="L1V38_000343"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBN1314923.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3826..4362)
                     /gene="cysE"
                     /locus_tag="L1V38_000344"
     CDS             complement(3826..4362)
                     /gene="cysE"
                     /locus_tag="L1V38_000344"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBN1314924.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4448..4687)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4684..6144)
                     /locus_tag="L1V38_000345"
     CDS             complement(4684..6144)
                     /locus_tag="L1V38_000345"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBN1314925.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6314..7471)
                     /locus_tag="L1V38_000346"
     CDS             complement(6314..7471)
                     /locus_tag="L1V38_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBN1314926.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7505..8875)
                     /gene="radA"
                     /locus_tag="L1V38_000347"
     CDS             complement(7505..8875)
                     /gene="radA"
                     /locus_tag="L1V38_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBN1314927.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(8938..9465)
                     /locus_tag="L1V38_000348"
     CDS             complement(8938..9465)
                     /locus_tag="L1V38_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBN1314928.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9695..10501
                     /gene="proB"
                     /locus_tag="L1V38_000349"
     CDS             9695..10501
                     /gene="proB"
                     /locus_tag="L1V38_000349"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBN1314929.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10498..11745
                     /locus_tag="L1V38_000350"
     CDS             10498..11745
                     /locus_tag="L1V38_000350"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBN1314930.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11821..12165
                     /locus_tag="L1V38_000351"
     CDS             11821..12165
                     /locus_tag="L1V38_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314931.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12282..12608)
                     /locus_tag="L1V38_000352"
     CDS             complement(12282..12608)
                     /locus_tag="L1V38_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314932.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13223..14425)
                     /locus_tag="L1V38_000353"
     CDS             complement(13223..14425)
                     /locus_tag="L1V38_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1314933.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14542..15057
                     /locus_tag="L1V38_000354"
     CDS             14542..15057
                     /locus_tag="L1V38_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1314934.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15256..15702)
                     /locus_tag="L1V38_000355"
     CDS             complement(15256..15702)
                     /locus_tag="L1V38_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1314935.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15749..17227)
                     /gene="msr(C)"
                     /locus_tag="L1V38_000356"
     CDS             complement(15749..17227)
                     /gene="msr(C)"
                     /locus_tag="L1V38_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1314936.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17581..18210)
                     /locus_tag="L1V38_000357"
     CDS             complement(17581..18210)
                     /locus_tag="L1V38_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1314937.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18194..18658)
                     /locus_tag="L1V38_000358"
     CDS             complement(18194..18658)
                     /locus_tag="L1V38_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1314938.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19145..20413)
                     /locus_tag="L1V38_000359"
     CDS             complement(19145..20413)
                     /locus_tag="L1V38_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1314939.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20644..21381)
                     /locus_tag="L1V38_000360"
     CDS             complement(20644..21381)
                     /locus_tag="L1V38_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1314940.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21448..22017)
                     /locus_tag="L1V38_000361"
     CDS             complement(21448..22017)
                     /locus_tag="L1V38_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1314941.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22145..23017
                     /locus_tag="L1V38_000362"
     CDS             22145..23017
                     /locus_tag="L1V38_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1314942.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23359..24231
                     /locus_tag="L1V38_000363"
     CDS             23359..24231
                     /locus_tag="L1V38_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1314943.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24228..26186
                     /locus_tag="L1V38_000364"
     CDS             24228..26186
                     /locus_tag="L1V38_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1314944.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26518..27369)
                     /locus_tag="L1V38_000365"
     CDS             complement(26518..27369)
                     /locus_tag="L1V38_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1314945.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27492..27959
                     /locus_tag="L1V38_000366"
     CDS             27492..27959
                     /locus_tag="L1V38_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBN1314946.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28222..28704)
                     /locus_tag="L1V38_000367"
     CDS             complement(28222..28704)
                     /locus_tag="L1V38_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBN1314947.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28804..29667)
                     /locus_tag="L1V38_000368"
     CDS             complement(28804..29667)
                     /locus_tag="L1V38_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1314948.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            30265..31140
                     /locus_tag="L1V38_000369"
     CDS             30265..31140
                     /locus_tag="L1V38_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314949.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(31285..31437)
                     /locus_tag="L1V38_000370"
                     /pseudo
     CDS             complement(31285..31437)
                     /locus_tag="L1V38_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(31705..33036)
                     /locus_tag="L1V38_000371"
     CDS             complement(31705..33036)
                     /locus_tag="L1V38_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1314950.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(33185..33898)
                     /locus_tag="L1V38_000372"
     CDS             complement(33185..33898)
                     /locus_tag="L1V38_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1314951.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            34073..35497
                     /locus_tag="L1V38_000373"
     CDS             34073..35497
                     /locus_tag="L1V38_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1314952.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            35796..36503
                     /locus_tag="L1V38_000374"
     CDS             35796..36503
                     /locus_tag="L1V38_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1314953.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            36490..36813
                     /locus_tag="L1V38_000375"
     CDS             36490..36813
                     /locus_tag="L1V38_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1314954.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(36902..37939)
                     /locus_tag="L1V38_000376"
     CDS             complement(36902..37939)
                     /locus_tag="L1V38_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1314955.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(38260..39243)
                     /locus_tag="L1V38_000377"
     CDS             complement(38260..39243)
                     /locus_tag="L1V38_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBN1314956.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(39658..40428)
                     /locus_tag="L1V38_000378"
     CDS             complement(39658..40428)
                     /locus_tag="L1V38_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314957.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(40421..41356)
                     /locus_tag="L1V38_000379"
     CDS             complement(40421..41356)
                     /locus_tag="L1V38_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1314958.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(41672..43321)
                     /locus_tag="L1V38_000380"
     CDS             complement(41672..43321)
                     /locus_tag="L1V38_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1314959.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(43438..46041)
                     /locus_tag="L1V38_000381"
     CDS             complement(43438..46041)
                     /locus_tag="L1V38_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1314960.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(46053..47102)
                     /locus_tag="L1V38_000382"
     CDS             complement(46053..47102)
                     /locus_tag="L1V38_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBN1314961.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(47128..47442)
                     /locus_tag="L1V38_000383"
     CDS             complement(47128..47442)
                     /locus_tag="L1V38_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBN1314962.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(47458..47904)
                     /locus_tag="L1V38_000384"
     CDS             complement(47458..47904)
                     /locus_tag="L1V38_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1314963.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(47905..49827)
                     /locus_tag="L1V38_000385"
     CDS             complement(47905..49827)
                     /locus_tag="L1V38_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBN1314964.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(50039..50935)
                     /locus_tag="L1V38_000386"
     CDS             complement(50039..50935)
                     /locus_tag="L1V38_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1314965.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(50928..51608)
                     /locus_tag="L1V38_000387"
     CDS             complement(50928..51608)
                     /locus_tag="L1V38_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1314966.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(51609..52391)
                     /locus_tag="L1V38_000388"
     CDS             complement(51609..52391)
                     /locus_tag="L1V38_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1314967.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(52384..53301)
                     /locus_tag="L1V38_000389"
     CDS             complement(52384..53301)
                     /locus_tag="L1V38_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1314968.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(53465..53788)
                     /locus_tag="L1V38_000390"
     CDS             complement(53465..53788)
                     /locus_tag="L1V38_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314969.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            54576..57803
                     /gene="fss3"
                     /locus_tag="L1V38_000391"
     CDS             54576..57803
                     /gene="fss3"
                     /locus_tag="L1V38_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1314970.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            57916..58230
                     /locus_tag="L1V38_000392"
     CDS             57916..58230
                     /locus_tag="L1V38_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1314971.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            58243..58617
                     /locus_tag="L1V38_000393"
     CDS             58243..58617
                     /locus_tag="L1V38_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1314972.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            58627..58962
                     /locus_tag="L1V38_000394"
     CDS             58627..58962
                     /locus_tag="L1V38_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBN1314973.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            59045..60385
                     /locus_tag="L1V38_000395"
     CDS             59045..60385
                     /locus_tag="L1V38_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1314974.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            60463..61137
                     /locus_tag="L1V38_000396"
     CDS             60463..61137
                     /locus_tag="L1V38_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1314975.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            61130..61294
                     /locus_tag="L1V38_000397"
     CDS             61130..61294
                     /locus_tag="L1V38_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314976.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            61370..62512
                     /gene="dcm"
                     /locus_tag="L1V38_000398"
                     /pseudo
     CDS             61370..62512
                     /gene="dcm"
                     /locus_tag="L1V38_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            62502..62792
                     /locus_tag="L1V38_000399"
     CDS             62502..62792
                     /locus_tag="L1V38_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314977.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            63051..64235
                     /locus_tag="L1V38_000400"
     CDS             63051..64235
                     /locus_tag="L1V38_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1314978.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            64232..64369
                     /locus_tag="L1V38_000401"
     CDS             64232..64369
                     /locus_tag="L1V38_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1314979.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        19269 a        12976 c        11706 g        20442 t
ORIGIN      
        1 tttcaagtgt ttttttattt tgagttttac tctcccgtaa gcgctcatta cttgcttgtg
       61 atccattgct aaacattcag ccatgtctac aaaatcaacg ccttgcatat aataatgaaa
      121 aattttagct tctatttttg aaaactggat ttcgcaattt tcgattgctt cttttaataa
      181 aagatgctga attgctaaag gttcttgcaa tgtgatctct gctaaaaagt ctggtccttc
      241 tgtctctatt ttttggtcga ttgagacttc atctttttga tcacgacgct tcagcgcgtt
      301 ctgcttcctc aacagagaat agatttgatt gcttataacg cttttataat aacttccaaa
      361 gctaacacct ttgctttttt cgtaagttct caatgcctga tataaagcga tccttgcttc
      421 ttgttcccaa tcctcagaaa cataatttct taaataatag gtgtttttca aacgtagtaa
      481 aagtggaaaa tatttttgat acagggcagc aaatgcttct tcgtcaccat tacgtgcagc
      541 gcgcaataac tcctcagaca taaaataatt cctccataaa ttcgtttatg gaggaatctt
      601 atcatcaatg attcatcgaa ctgattagaa cgatatgtta tttatttttt ctcattaaat
      661 cgtccaattt ttgggacaat ttttttaact gctcttcatt ccatggagaa ttacgtcgga
      721 aatcaataaa atgcatatct ttattttctt gggctattgt tttttccgtt ttttttatcg
      781 tcttatataa ttcataagca gaagttcgta atgctccttg ggaaaagatc atccactgtt
      841 ctgctaaatc gcttgtcgcc actgtcactt gtgtcaaacg gtcattcagc tgaccagcga
      901 ttctctcgat ataactgtca gccgtttcgt cttctttcgt aaaaacaaca tccaactggt
      961 atttcttata attttgttgg atgcccggaa ctagttgggc atcgaagaca acgatgactt
     1021 ccattccttc atatttcgca taatttgata aacgatgtaa aagagcttct cttgcatccg
     1081 ccattttgtc ctgcttttta agctggacaa gttccggcca cgaaccaatc atgttgtagc
     1141 cgtctacaat caacagctgt tttttcatgg tctactcccc ctgacgttgg gaaaaagcct
     1201 gatacataag caaaccagca gcaacactgg catttaagct ctggacgtgc ccggtcatcg
     1261 ggatcgtcag caattcatcc atttcttttt tcaatcctgg actcattcct ttgccttcat
     1321 taccaatgac taaagcaatt gatcctttgg cattccattt ttggaagttt gtgccggtca
     1381 tatctgtgcc aaatacccaa aatcctgttt ctttgagctg ttgcacagct tgtaccaaat
     1441 tcgtcacgcg tgcaacaggg acatgttcga ctgccccagt ggaagtcttt gttacgatag
     1501 gtgtgattcc aactgctcgg tgttttggta tgatcacacc atcgacgcca cttgcgtctg
     1561 ctgtccgtaa aatcgaccca aaattgtgtg gatcttcgat gctatccaaa atcaaaaaga
     1621 aggggtcttc ttttttctct tttgttcgtt caatcagttg gtcaagggat aaatattcat
     1681 aaggtgtaat cgcaagaacg actccttgat gcacgccgtg atcgctcaaa gtttctaatt
     1741 tttgtttagg aacccatttg actggcacag cttgttcacg tgcgatttct ttcagttctt
     1801 ctactttttc tcctcgtgaa tcttcttgaa gaaagagttt attccctcgc ccttgttgta
     1861 gcgcttctac tgcggcatgg tgcccaaaga cgaaattatc ttctaatgct tcttcatttt
     1921 gatcagaaac tgactgattt cgtccagttt gctttttatt tgaatatcta ttttgttttt
     1981 tgtcttcaaa tccacgtttc gattgatgtt tgtttgttct ttctttaccc atttttttca
     2041 ccaactttct gaatacacca gcggatcaat tcttccatcc gctcggtttg ttttgtcaaa
     2101 tgcagatagc ccatgagcgc ttcgaaccct gttgcgaccc gatacgtcgt aacatcagca
     2161 ttttttgcgc tcgtatggct tttagcattt cttcctctgc gataataaag ttcttcttct
     2221 tctgtcaaaa gatgttcttc cagcatttgc tgaatcaaaa aggcttgtgc attcgcagaa
     2281 acataattcg ttgccgcacg atgcagctta ttgggttttg tttctccttg atcaatcagg
     2341 tggtcacgaa catagatttc gtaaatcgca tctccaacat aagccaaggc taaaccgttc
     2401 aattgtgtgt aatctctcat gcttctcttc tccatcgggt tccttgcggt gtatcttcta
     2461 ataagatccc tttttctttc aacaaatcac gaatttcgtc gcttcggaca aaatcacgat
     2521 tgcttcttgc ttgatttcgt tcttcgatca attgttcaat ctcttcatct aataactctt
     2581 ctgctgtaaa taaaataccg aagatcgaaa gccattgcga gaataaagct tctccttgtg
     2641 ccaagacagc ggcagaaact ttcggctggt ctagataagt gttcagccac ttagcaagct
     2701 catagaccac tgtgatccca tttgctgcat taaaatcatc gtccatttct tcgatgaatc
     2761 gctgttctaa attttctaac aaagcgattt tatccgcatc atctgccaaa ttctctgagg
     2821 cagtttcttg gcggaatttc aaattgtcaa acgtattctt cagtcgttgt aaattggtgg
     2881 ctgcttcttt catcgtcgtt tcactgtagc ggatcggacg acggtattgt gtggtcgcca
     2941 tgaagaaacg caagacttgt ggatcaacgt ttttgatcat ttcatgtaca gtgatgaaat
     3001 tccctagaga tttactcatt ttttcatcgt cttcgccaat cgttacatag ccattgtgca
     3061 tccagtaatt agcgaatttt ttccctgttt tcgcttcact ttgtgcgatt tcattttcat
     3121 gatgaggaaa ttctaaatct tgcccgccac catggatatc gatcgtttct cctaaatgtt
     3181 ttgttgccat aacggaacat tcaatatgcc aaccgggacg tcctttgccc catggtgaat
     3241 cccaagaaat ctcgccaggt tttgcttgtt tccataaagc gaaatctaat gggtcttctt
     3301 tttgctgctg ttcttcccct gtacgctgac ttgctccgac ttccagttca tcgatggatt
     3361 ggtcacttaa tttcccataa ttttcaaatt tacgggtacg gtaatacaca tcacctgaag
     3421 attcataagc atagcctttt tcaaccaaca cttgaataaa tgctaaaata tctggcatat
     3481 gatccatgac tcttggatgc agtgtagcag gttcgacatt caacgctttc gtatcttctt
     3541 caaatgctcg gatgaaacga tcagcaactt ctggtgctgt aatacctaat tcgtttgctg
     3601 tacggatgat tttatcgtct acatccgtga aattcgatac gaaatcgact ttatagcctc
     3661 gatattcaaa atagcgtcga attgtatcga aagcaatggt gctacgagca tttccgatat
     3721 ggatataatt atacacagtc ggtccgcaga catacatacc gacatgtccc ttttgtatag
     3781 ggatgaattc ttcttttttt ctggtcaatg tattgtagat ttttatcatt ctgatctcct
     3841 cactttttct cctttgattc gaacgacttt tgctggtact cctaccgctg tagcgtcgtc
     3901 tggaacatct ttcaacacaa cggcacctgc accgattttg gcgttttttc cgatcgttac
     3961 cggtcctaat atctgcgcat tcgcagagag catggctcct tgtttaacag ttgggtgtct
     4021 tttacccgtt tcttttcctg tgccgcctaa tgttacgcca tggaataaaa tcacatcgtc
     4081 ctcgatttct gcggtttcgc caatgacgat tcccattcca tggtcgatga acacgccagt
     4141 tccaatcgtt gctcctggat ggatctcaac accagttagg aaacgccaga attgagcatt
     4201 gatcttcgcc aataaaaaga gccggtgctg atataaaaaa tgagagaaac gatgccaaaa
     4261 caaggcatga aaaccagggt atgtcaaaac gatctcagct gtcgaacgtg cagccggatc
     4321 gtttctcttt gctgcatcaa tcgctcgggt aaaccaactc atgactttcc actcctttcg
     4381 taagaatttt atgtaggaaa tcatcttctt ataaagaaaa gaagcgcctt ttaaataagt
     4441 ttccttatca aaagacgctt tccgcgtggt tccacttttc ttcataatca atgattatct
     4501 ctgacagcta acgcctgtta tacgttcttg gctactttgt ttcctataaa acagtttttc
     4561 ctgttttctg tgtttcgcca agaccactcc cagaggcatt tcggcaacca ttcattgata
     4621 ccttgcacca cccggtatct ctcttgtaat gatcagctgc ttactttttt ctgttcatcg
     4681 tgtttagttc agtacttgat ttaaatgtgc taatgatttt tcacgaccaa gcaattcgat
     4741 cgtttcaggc aattctggac catgcatttg tcctgataca gctacacgga ttggcatgaa
     4801 aagatttttt ccttttacgc cagtttcttt ttgaacagct ttgatggcag ctttgacagt
     4861 tggagcatct actacttcca tttgttctag ctgtgctttg aatgcgtgga gaacagtagg
     4921 aactgtttca ccagcaagta cttcttttgc tgcttcattc aatacaggat gttcattgaa
     4981 aaatagcgta gacagatcaa cgatttctgc agcatagctc atttgaggtt gatacaggct
     5041 aacgatcttc ttcacccatt cgattgtctt ttcatctggg ttttctgcta cacgtccatc
     5101 agcgattaga taaggcagac acatgtcagt aaatgcatct agatccattg ctttgatgta
     5161 atggttgttt acccattgca gttttttcgc atcgaaagct gcgggtgatt tacttaggcg
     5221 ttttggatcg aacattttga tcaattcttg gtgttcgaag atttcgtctt cgcccacagg
     5281 tgaccagccc aataatgcaa taaagttgaa cattgcatct ggtagatagc ctaattcgcg
     5341 atattgttcg ataaattgca agattgattc gtcacgtttg cttagttttt tacctgtttc
     5401 actgttgatg atcaatgtca tatgtccgaa ggttggtggt gtccagccaa atgcttcata
     5461 gatcatcagt tgttttggtg tattggcaat atggtcatct ccacgtaaaa cgtgagtgat
     5521 tttcatcaaa tgatcatcga ccgcaacagc aaaattataa gttggcatac catcgcgttt
     5581 ttggatgaca aagtcgccac cgatattatc ggattcgaac gaaatagcgc ctttcaccat
     5641 atctgtaaat gcgtattctg tattgcgagg cacacggaaa cgtacaacag attctagacc
     5701 ttgtgcttct ttttctgctt gttcttcagg tgtcaagttc gcacatgttc ctgcgtaatg
     5761 aggcatttct cctcttgcgc gttgtgcttc ccgttctgct tctaattctt cttctgtgca
     5821 atagcatttg tatgctcgat tgctagcaag cagctgatca atcagcggtt gatagatttc
     5881 tttacgttca gattgacggt aagggccgta ttctccagga ttttcaggag attcatccca
     5941 attcattccc aaccaagcaa ggttttccaa ctggcttttt tcgccatctt cgatattacg
     6001 tttttggtca gtatcctcaa tacgaataat aaagtctcca tcattgtggc gggcaaacaa
     6061 ataattgaat aatgcagttc ttgcatttcc aatatgcagg tgcccagttg gacttggtgc
     6121 atagcgtacg cgtactttcg tcattttctt cctcttcttt caaactagac tttgactaac
     6181 agcaaaaatt ccgtcagtta cggcttctca aatatcattt atttaaagcc actcagcaca
     6241 aattttacct tttctaaggt aaatagtaaa gccaactggt tgaatttcct taccagttgg
     6301 ctgaatttct tttttatttt gattgtttag tctttttctc tgtctctttt ttattgtcga
     6361 ttcctcgtcc tgcatgtgca ggtttagcaa agatcatgcg tccagcagct gtttgaaggg
     6421 cacttgttac aacgacttcg atacgttcat tcatgtaatg ctgtccatct tctacgacaa
     6481 ccatcgtgcc gtcatcaagg taggctactc cttgttggcg ttctgtcccg gcttttacta
     6541 ctagaacatt catcgtttca ccagggatga cgactggttt tacggcattt gccaacgcat
     6601 tgatattaag aacaggtaca ttttggaatt cagagacttt attcaagtta tagtcattgg
     6661 ttacaatgac accatctaaa agcttagcca atttgatcaa tttgctgtct acttcactga
     6721 tatcttcaaa gtctccatcg tacatttcga cagatatacc ctcttctttt tgcaaggcat
     6781 ttaggatatc taatccgcga cgaccacgca cacgtttcaa actatcccct gagtccgcga
     6841 tgtattgtag ttcgtaaaga acaaaattag ggatcatcaa ggttccttct aagaatccag
     6901 tctttgtaat atcataaatc cgaccgtcaa tgatcacgct tgtatccaag attttatatt
     6961 tatggaaatt ttctcctgat tttcgttcta acagttgact ctcaacttga ctagctgttt
     7021 cttgctcgat ttttttgctt cgtgaaccaa aaactttctt ccattcttcg attcgtgtcg
     7081 ttcccattct caatcccaga tagcctaaga tgatcatcag taaaatcggc aatacactat
     7141 tgacgaatgg aatttccata ttgtaaagag gggtcgagat cacaacacct aaagtcaatc
     7201 cgatgatcgc accgatcgca ccgaagagaa gataagtcaa gctgacctca cttagttttt
     7261 gttctacttg tttgataata gctgagatat gtttggccaa cagcaaagat aataaaaaga
     7321 aaataagtgc gcctaacagg ctgttggtaa atgtattatt cagccatccg tttgactgtt
     7381 gaccgattgc ctgccaagct gagggtaaaa atgaaatacc caagcttgcg ccgacaatga
     7441 tcatcagcaa agtaatgaca cgtttttgca tcgtttttcc tccgtttcga caatcattta
     7501 ttagttagcg gaacacacgc ttcaacgttt cagccaaagt tgctactcca actatctcga
     7561 ttccttttgg cgcttcccag ttacctaagt tgtttttagg taggtatact tttgtgaagc
     7621 cgagtttttg gacttctttg actcgttgtt caatatgact gacacgtctg atttctccag
     7681 tcagtccaat ttcaccgatg aaacattccg ttggctgtgt tcctttttct ttatagcttg
     7741 aagcaatact gacagcgata gctaaatcaa tcgctggttc atttaatttt accccacctg
     7801 cagcttttaa gtaagcatct tgattctgaa gaagcaaccc agctcttttt tccagcactg
     7861 ccatgatcag agatacccga ttgaaatcaa gacctgttgt tgttcgtttg gcatttccga
     7921 acatagtagg tgtgactaat gcttggatct ctaccaaaat tggacgtgtc ccttccattg
     7981 ccacaacgat agcagagcca gttgcaccgt ctaggcgttc ttctaagaaa atctgtgaag
     8041 gattagcgac ttcttccaat ccatgctcat gcatttcaaa aatcccaatc tcattcgttg
     8101 agccaaatcg gttttttact gctcgcaaaa tccgaaaact atgatgttgt tcaccttcaa
     8161 aatataacac cgtatccacc atatgttcta acattcttgg gccggcgatc gagccttctt
     8221 tggtaacatg accgacgata aaaatggcta tcccatttgt tttagcggtt ttgagtagtt
     8281 ctgcagtggt ttctcttact tggctgacac ttcctgccac acttgtgatg tctggctgcg
     8341 tcatcgtttg gatggaatca atgataacat aatcagggga gatatgttcg atggcacgac
     8401 tgatttcgtt catatctgtt tcagcgtata gataaaattc tgtgttgata cttccgaggc
     8461 gttccgcgcg taattttatc tgctctgcgc tttcttcgcc ggatacatat aagacttttc
     8521 cgcctatggc tgctaattgc tgagaaactt gtaacagcaa agtggatttc ccgatacctg
     8581 gatcgccacc aatcaagacc atagaccctg gcaccacacc tccgcctaac acacggttca
     8641 gttcttctaa ttttgttttg atccgaggtt cttttttagg gacgacgtct gcgatttttg
     8701 ttggttttgc tttttctcct gtcaaacttg tccgagttct gcggtccgtt gtatcttgtt
     8761 cgatttcttc gaccatcgta ttccattttc cgcaatttgg gcagcgtccc aagaacttag
     8821 gcgacacata cccgcaattt tggcaaacaa attgtacttt tgattttttt gccattgtac
     8881 cgcctccttt tatcctaatc atgagacatt aaatcaagct taagtatctt taacgtttta
     8941 tttactggaa gaaccaaatc cgccttgacg ttgagcagtc gtttgatctt gatctgcttt
     9001 taaaaacggc aaaaagatcc cttggccgat acgctcgcct tttttgatca ctacatcctt
     9061 gaaaccaaag ttggtgaatt ggaacatgat atggccttca tttgcctcat tattgtaata
     9121 atcactgtca atcacaccta ctccgtttgt caacactaaa aaccgcttca acggattgct
     9181 tgaacggtta gcaagctgca aaaattcatc ttctcccatg taagctttga ttccagtagg
     9241 cacgagggtt ggtttcaatt gtttttcatt ttctgataca tcttttttca atccatctgc
     9301 gactgtttcc aacccctttt tccagcctgc tttccagata cttggaatca cgacctcttc
     9361 tgctgcttca aaatcatagc cagcagcatg atgtgtagcg cgctgcggta gattgatatt
     9421 ttgatcttta tatttagaaa taacttcaaa tcctcttttt ctcaccggtt ttcctcccta
     9481 aataaactac tcctattcta acatatccga ggctgtaaaa gactttcttt acaaattctt
     9541 caagaaattc tgctatctta aagtaaacca ttaattcgtt ctttttccaa acgactgcaa
     9601 gttgtacaaa aaaactattt tttacatgac tttactcgtc aaaacaagta gaatagaacg
     9661 aaattaatga gtggatattt gattgaggtg tcacatgcgt aaagaaatta aaaatgcaaa
     9721 acgaattatt gtcaaagtag gaacaagtac attgatttat cccaatggaa atatcaatct
     9781 tgcggcaatc gatcagttag cttttgtcct ttctgatctt agaaatcggg gaaaggaagt
     9841 gatcttagtc tcatcaggag ctgtaggcgt tggtatgcat aaattacatt tgtcagaacg
     9901 tccgactttg attcctgaac agcaagctgc ggcggctgtt ggtcaagccg aactgatgaa
     9961 tatctataat caaagattca gtgtatataa tcaacagacg gcacagatcc tcgtgacaag
    10021 agacgtggta gattatcctg aaagtcgtaa aaatgtgagg aatacattgg aacagctttt
    10081 gattatggac acgatcccta tcgtgaacga aaacgatact gtagcagtgg atgaattaga
    10141 tcatctgaca aaatttggcg ataatgatca gctgtcagcc atcatggcaa aacttgtcgc
    10201 ggcagacctt ttgatcgtcc tttctgatat cgacgggttt tattcagata atccgactac
    10261 aaatcccgag gctcagatgt atcgctatat cgataaaatc gatgaaaaga ttctggcaca
    10321 agcaggtggt gctggtagca catttggaac aggcggtatg cagagtaaat taaaagccgc
    10381 ttctaggata tttgaagcaa acagcgcaat gattttagca aatggaaaaa atccggcaat
    10441 tatttttgat attcttgcag gaaaagaagt aggtacttta tttaaggagg acttgaaatg
    10501 actgacttga tgcaattagg acaacaggca aaagatagcg cgcaacaact agcacttatg
    10561 cctacaaacc gcaaaaatga gctacttgtt caaatggcac aaaccatcaa aaagaatcaa
    10621 caagcgatca ttgaagcaaa tcataaagac ttagaaaaag cagtcgaaaa caatatcagt
    10681 gaaacgatgc aagaccgctt gcagctgaca cctgagcgaa tcaatgccat ggctacagag
    10741 atcgaaaaaa ttgcttcgtt agacgatcct attggaaaag tagatgagat gtggacgaac
    10801 accgacggat tgagaatcgg caaaaagcgc gtgccactag gcgtgatcgg catcatttac
    10861 gaatctcgtc caaatgtcac gacagatgca gctagtctag cattcaaatc agggaatgcc
    10921 gttatccttc gcggtggcaa agaagcattc ttctcgaatc aattattagt ccaattattg
    10981 cagcaagtac tggtcagtgc tggcgaatct ccttatgcca tccagtttgt cgatgatact
    11041 tctcatgaaa ctgcaggaca gttgatgcga ttgacagaat acttagatgt gctgattcct
    11101 cgaggcggag caaaattaat ccaacgagtc aaagaacagg caacggtacc tatcattgaa
    11161 acaggtacag gaaataatca cgtatatatc gataaagaag cacagttatc tatggcagtg
    11221 aacatcatcg tcaatgcaaa agcttcccgt ccatctgtct gtaacgcggc agaaacattg
    11281 ctgatccatt ctgagatcgc accttttttc ttgccagcta ttgaaaaaga actggtagaa
    11341 cacggggtct ctttacgtgc ggatgctcgt gcgttagaat atctagagac ggctgcttta
    11401 gcagaagaca cagattggga tactgaatat ctagattata tccttgctgt caaagtggtc
    11461 gattctttgg atgaagcaat tgcacatatc aatcggcata atactaaaca ttcagaaacg
    11521 atcgtgacag atagttatgc ggctagtcaa cgtttcttaa atgaagtgga cgcggcggct
    11581 gtctatgtca atgcctccac tcgttttaca gacggatcgg tatttggttt tggtgcagag
    11641 attggtatct ctactcaaaa gttgcatgcc cgtggtccaa tggggttaaa tgaattaact
    11701 tccacaaaat atatcattta tggcgatgga caaatccgcg aataatgttt cgtgtgaaac
    11761 attattcccg ccttttgcct tttttctgta aaggttctat ccaactagaa aggtgtcaat
    11821 atgtttgaaa ttttaatgat tttttttatt taccttattt ctctgaatat cgctgctttt
    11881 ctgggagtcg gtattttatc ccttttcttt caattcaaaa aacgaagcat agggagtcaa
    11941 cgggaaaaat ggtcgcagta ttttgacaaa atcgggcaaa aagggctggt tacacgcttg
    12001 cacattagtt acatggttgc attatgctta ttagcgacaa tcaattacta ttcttttttc
    12061 gatcattcaa tcgcttatac gattacgcta ctgattgctg ggatttttca cttatcttat
    12121 aaatatcagc tgaataaaaa ccacttgaat cggactttcc gctaaaaaat atccgtacga
    12181 taagtagagt gccttgaaga tcggcaaaaa actgccggac tttttagagg ctgtgacaaa
    12241 gattttgtca cagcctcttt ttccatataa acggcgttcg cctaccagct gcctggtaaa
    12301 tctgtttcct cttcgttaag aagcgaaaat ccgtcaaatg tttcgccatc ataataacga
    12361 agcagctcat ccatggacaa gttcatcgtt ttttcttttt cttcttccgc tgattcagcc
    12421 agtagctgtt cccgatacac ctgatacata ccagctattt tttgctgcat cgcttttcta
    12481 gtttcacctt ccgcattgat tattggcaat tctttgatat agccacgata aatcaaccga
    12541 tcatctgaaa attcaatggg taattcaacg agtgtcaacc cgacttcctg aaaatattct
    12601 tccagcatct attatccccc cattcttttt cttaaatgaa ttttagctta cctactgaaa
    12661 attttccagt ttcattattt tgagaaaaaa agggaatgtg acaaaaatcg tgtcacatcc
    12721 cctttttccg aataaatggt gttcttctgc caactcctca atcataagtc acaatattca
    12781 acaaacatga gaaactgttt tttgaaattg ttccttgtga ttcagagtta aacgacagtc
    12841 tcacaacctc ttggtaaacg gcgttcaatc agctgaccct cggtattagc tcaaaaaacg
    12901 gtaaaatatg agaagctatt tttccgtttt gtttctctaa tacttaggat aaaacgctga
    12961 ttttacaacc tctgttaaac ggtgttcaat cagctgtcct tcggtattag ctcaaaaaac
    13021 ggcaaaatat gaggaactat ttttccgttt gtttctctaa tactcaggac aaaacgctga
    13081 ttttacaacc tcctgataaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    13141 aaacgaaaaa tatgagaagc tatttttgtt tggctgttct tatgacttga tgcaggacag
    13201 ctttttcaca acctctgatt tcttattctt cttcatttgt agcaaaataa ttacggtgat
    13261 aaatgataca acatacactg ataagaacaa tggcacctgc aaaataaaac gcatagcttt
    13321 caccaatatg ttcaccaatc acacctgcaa taaatggtgc taaagctcca ccgaaaaagc
    13381 ggacaaaact atagctggac gaagcaacgt ttcgttgcag acctggtatt tccatagcaa
    13441 tcgtcgtcaa cagtgtattg ataattcctt ggaaaaatcc tgctaacaca atgctgatcg
    13501 gtacaaggac tggcatagaa gttccagctc ctaataacag caaacaaata atgaataaga
    13561 caaatgctgc taaaattgtc cgataagtcg taaacttccg ctcaagagcc ggtgcaacga
    13621 aaatcgaagc aatagccaga agcacacccc agccaaaaaa tacaaaaccg acttctaatt
    13681 cagaatagcc aatcaataaa aatggcgcat acgcaagtaa agtaaagaat ccgaaattat
    13741 ataacaatgc gattagtcca actgaacgaa gtttatgatt gcttaacgct ttgacacctt
    13801 cccaaaggcc tacttttctc tttggtttct cagtttcagg taaaagtacc gctagggcta
    13861 taaaaccgca aaacatcaaa aatgctaccc caaaaaatgg ataacgccat gaaccactgc
    13921 ccaagacccc accgactaga gggccaacag ccattccgca gccaagtgct gcttcataca
    13981 tcatgattgc tttttctgtg ttaccaacta aaatactgac gatcgttgct aaagcagtag
    14041 agacaaataa agcattcccg acaccccagc cggcacgtaa cccaatcagc attccgatat
    14101 tcccagataa tccgccaaga ccagcgaata caacgatgat aaacaatcct gtcatcaatg
    14161 tttttttcaa accgatccga ctagataaga aacctgtaaa tagcatcacc acaccagtga
    14221 ctaacatgta actagtaaat aacagggtcg tttcagctgg cgtagcgttt aactgtgcag
    14281 caatcgtttt taagattggg tctactagac ccactcccat aaaagcgatc atacaggtag
    14341 ctgctacaac tagcgctgaa cttttcccct ttgtttcttc atttgtttgt tcttgtatat
    14401 ctatttgatt ctccaatatt tccatccctt tctctctatt agcatcatac atgatttatt
    14461 ttacatgtca atatgcacat gtaaaacgtg gaaactttac tgtgatataa taaagaaaat
    14521 aagacgagag gtaggatttt tatgaatact ttagcctata tattattatg cgtgctttta
    14581 tccaaaccac gttctgggta tgaattgaag cagctgatca caattttttg ggaagcccat
    14641 cacagtcaga tctatacaac gcttgccaag ttagaccagc agggttatgt gaccgttttg
    14701 gacaaagacg agcactctca aaaaaagatc taccacttga ctgatgaagg acgtgctctt
    14761 gtagaggaat ggatcaaaga ggaaactccc gctcctacgc aaaaagatga atttctagca
    14821 aaaatctatg ctttttcgac gctcgataaa acaacagcta ctggactgct attcactaga
    14881 gaacaacagc tgaacaaaat catgcaaaaa aatcaaaaaa aattgaatga cctctcgcta
    14941 gacaagaaac aagaatttgg acgttatgtt gtgatccagc gcagaattat gctttgtcag
    15001 caggaactcc aatggtgtca gcaagtaaga gaacaaatgc agcagttttt tgagtaaggg
    15061 ataaacagaa cctttctaga aatatctatt gaagagcaaa ttatcttcaa taaaagagca
    15121 atacagttgg aaaagaaaaa gcgatccgaa cgacaggcca aaacctatcg ttcggatcac
    15181 tatttttcta gaactgcatt caagagacta tgacaaaaag catgccaagg ccttttttca
    15241 aataacagtg ttccatcatt cattactttg aattgctttt agcacacttc ttgaaagcgg
    15301 gccaacgatg atcaactgca acggtaaagc ggcaatcaca ttcattttcc aagcattcat
    15361 ataagcagag aataattgat caggtattcc ttgttccatg atcacaccga ataaagacat
    15421 acatgtcacc attcctaaaa ccatcaagca tgaaatagtt aagatcattt ggaccttgct
    15481 ttctggattt actggtagtt taaaggcaat ttttttcgcc agcacaccga tgatgaagac
    15541 atccaaaatg aaagccacca cgaatccagg cactagacca atcaacaaac ttgataaatg
    15601 aagatcttga tgcagccata aattatacgc gctcatcccc aagaccatca aaaaacacat
    15661 cattgttgta aaaattattc cttctttttt atttgtaggc aatctgtacc actcctttaa
    15721 atttgtcacg aaaatcatcg tagcacattt aaaaatttct cgtaagtact ttttttattt
    15781 tctgcccttt tatttcataa acttcatcag ccgtacgctc gacaaagtaa gaatcatgag
    15841 aagtaaacaa aatcgttccc ggatatattt gcattagctt ctctaaagct tcgatcgttg
    15901 ccatatcaat aaaattagtc ggttcatcta acagcaacac attacttggc ttagtaaaaa
    15961 gcaaagcaat cgtcagacgg gtcgcttctc ccccacttaa tgtacataac ggtttcgtca
    16021 aagtttcctg agcaaaccct aagtgattca gcaaactacg gacaagcgat tctgaaaact
    16081 ctgtttgtct catgacaaaa cgaatgatgg attcttcaga tgtcatttga taaccctttt
    16141 gctgatatac ttgaaagctt actttcggag agagaaggat tccttctcct tgtttgcgga
    16201 tatgttctaa taaggttgtc ttacctgaac cattttcacc gacaatcgcg atttttttac
    16261 ctaaagaaaa ctgaaaatca ccatttacca gtaatgttct cccacttctt tccaattgga
    16321 cattttgtcc catgatggga tagcggctgt ggagttcaag agattttggt actggaaaac
    16381 ggatttgttt catctgctgc ggcttggttg tttctcctat tttttggagt cttctctcta
    16441 atgttttcgc attcttttgg atggcttttt gtacactgtc tttttgttta gaggaagaca
    16501 accgatccag tctgatttgt tgctttttct ttttactgga cactttttcc aacttttccg
    16561 cttgtttttt cttttcttgg atcgattttt ccaatcgttt tttctctttc atgatcgact
    16621 ctgcttctcg tagctgagtc tttttctcca attccttttg agtgagatag gcactataat
    16681 tccccgaaaa ctctcggatt tctccgtctt ttacttccca gattttcgat gctagctcat
    16741 ctagaaaata gcgatcatga ctaacaaaaa ccagcgtacc ataataataa cgaagctctt
    16801 caatcagtcg atcaatactt tttctatcta gatgggttgt tggctcgtct agaagcatcc
    16861 cttgttcata agaagaaaga agacgtatca actcgatctt tcgttcttcc cctccgctcc
    16921 atttccgctc tgaagtttct tccagtctta actggaaatg actggctaat tccaaattta
    16981 ggtcctttgc ttcagcgaga taggttaatt gaggcaggta gttgaaggtg atctctgttt
    17041 ggattttccc atgatcggga aaaagttcac cggctattag tttgagcaaa gtcgatttac
    17101 cgacaccatt ttctcctatg atccctatac gatcttgctg atagacacga agagaatcaa
    17161 tagatagttc tagctggttg ccaaagctga cttgtagatt tgttatattt actgctaaat
    17221 tttccatatg ttttacactc ctatttcatg taaaacaaca attatcgata ctaaaaaaga
    17281 gcagaaaaat ctgtttgcaa aaaaactgca tcacatcttt tcctactctg aacgaaataa
    17341 ctatgactaa atcaccaaat ctgtcatagc tttcacctat tctactgtcg ttcgaaaaaa
    17401 tggacatact ccatccatga aattgttgtt tatacatgtc ttttgaattt atttagttgt
    17461 tattcaaaag ttcgaaacgt aatttcatcg atgcagtcat ttttccgacc tcctttttta
    17521 ttaggttacc acacacgatt caaaaaaagc aatagctact gaatagtaac tgaaaacctt
    17581 ttattcgaac atagtgatct tttctggtgc taaacgaaca gactcgtaac cttcttctac
    17641 cgcttttcct attgataaaa taataactgg aacataacgg tctttatcca aaccaaatgc
    17701 ctctgccaac tgatctgctt cgaatccacc aattggattt gtttcatagc catgatcacg
    17761 cgcaactaac atgaattgca tagccgctaa gctagaatcg actttgacta catcgttcat
    17821 ttcttctctt gaaaaactct tgtaataagg aatgatcgca gctaattgtt gatctctgac
    17881 ttcttttggc atcttccctg attcgtaagc ttggttgtag atttcttcgc catattcgta
    17941 acattgcata tcgccaaaaa tcatgaccat tgcagaagaa gtatcatttt gtctcgtatt
    18001 gaaacggatc aaaggacgca agatttcttt tgcttcctcg ctttcagcga ccacaaagcg
    18061 ccatggtttc atattgacag aagaaggtgc agtcgtcgct tctttgatca tttccagcat
    18121 ttcttcgtgt gggattttgt atgtttcatc atatacgcga acggatcttc taccagtcat
    18181 aattgttgaa aaatcatttt tttgttccat tattattaac ctctttcgtt tctgttgtta
    18241 tattgcaaag ttgggtattc aatttatcta aaagtgttag aaattgtttc atttctacat
    18301 cgctgaaagc cggggatagc acggaacctg tatctttatg gtccatttca caatgcttga
    18361 ttttcttctg ggctttttct gttagcgcta catacacttc ccggttgttc tgaggatttc
    18421 tctgacgcga aacatagcca tttgcttcca ataccttcag atgacgagta actgctcctt
    18481 gatcaatctg caacttttct tgcaaactgc tttgtagcaa tggattttct tctttcagtc
    18541 tcatcatgat ctcgtatcta gtaagactta taccgatatt ttcttcaaag atctggacga
    18601 ttttttgatc ggctaatttg atttgatata aaaggtgact aatctcttct aaagacataa
    18661 tttcctcctt tctaataatt gactcgtcaa cgattgactt gtcaataata gaataaaaaa
    18721 agaaaaaagt caaagaatca gctgtgtaat aaaaaaaacg ctctcaatag aaaagtatag
    18781 agaaaagaaa ttttttgtag aatgaacgga aaaaatgata aagaaagcac aacgctaaaa
    18841 ccaagattat tgattcttat caaactatag aagatagctc ttctgcagta gataatttta
    18901 caccgccaaa aatttccgaa atcgcctttt gcaagaatcc cgtcgaatat tagaaattgg
    18961 atcagtatgc ttaaacagta ataaaaaagt tatgacaaga tgttgtcaca accttttttg
    19021 agtaaacggt gttcaaaaac ttgcatctgc ggtaataagt tcaaccaaac aaaaaacatg
    19081 aaaatctgtt tttgtttggc tgttcttact acttgatgca gggcagcttt ttcactacct
    19141 ctttttaata accataaaat cctattcctt catatctcca gcccatcggt gttagccaat
    19201 ctctttcctt agcactcaag gtatagtgat gggtaccagt tttttcattt ggattaaata
    19261 gtcgataaat tggcttggaa ccaccagaat aaaaacttag accttcataa cgccaaccga
    19321 tttttgttaa agagttgatc tcagattgtg ccattgtgta atgatggtct ccactgtaag
    19381 gattgtataa acggtagaca ggttgtccgc tgtttggtgc ttgccaagca atcccttcat
    19441 attcccagcc tacagttggc agataatttt tttctccggc attcaatgta tataaatgtt
    19501 ctcctgtatg acggttatac agacgataca tcggagaagt tgaagttggt gctgtatcat
    19561 actgtgtcag attataggtt tcgattacat tgttcaatgt agaaccataa ttaggcgcag
    19621 tggcataacg acctgttagc caagccgtag catctttgta agagttcgta ttgcttttcc
    19681 atgcaccgga atagtagtaa acgcctggct gaaaagaagt cgtcttcaat accgttacgt
    19741 tatcttgcaa tgattctttg tacgaaggat attttctaaa agcggcattc accgtaatcc
    19801 attgcccatt cacatattcc gaagtaggca tcgtaacaga ttggccatta tagcttcctt
    19861 taatcccaaa tagattgtaa ttaggggcag aagccaaagt actgttcccc cagccacttt
    19921 caacgatggc ttgagcaatc atgactgatg catataagtc attggcactt gccaaacttt
    19981 gtgcagttga ggcaatacta tcaatgaacg cttgttgaga attagcagat gagcgagcat
    20041 aaaaagcata gccagtatag ttttcgaatt cagacaaatc tgcttgatgg gtatgtgtca
    20101 atgtttgccc atctgtcaat tggttcgtga tttcttctgc attctctgga ttgttctgag
    20161 cttctgctga tgtactgtct tcggtttgtg tttgttctgt tgtttcagtt gttggttctt
    20221 cggttgaaat tgtattttct gagacagtag ctgactgcaa agtactttct gtatcgtttt
    20281 caattcctgt ttctgaagaa ctcgatgtct gagttgcgac agtttctgtc gattcttcag
    20341 ctagcactgt tgtgttggca actgctagat ttcctaaaag aataacgcta aataataaat
    20401 tctttgcttt catctttttt ctcctttgaa ttatgaaact tttcctaaat aacagtgtaa
    20461 ctaaaaaagt aaaagcaagt caatgtccat atttaaataa catttgtttc tttttaataa
    20521 atttgctttt tctgcataaa aagacgtaaa tgaagaatat tcttctccat tcacgcctta
    20581 aattgatggt cgtttgaata actatttaac aagtaattct ctctggatat tatccgttat
    20641 ggattatact tcctgtgtcg tcggacggat aatcatgttg ctgacagaca tccggtctgg
    20701 cgtttctatc gcaaatgcta cagcagaagc tatatcttca gatgttaatc cccattcttt
    20761 ttgcgcttca tgaagttcaa gagcagcctt tttgtcgctg atggtttgat ataattcagt
    20821 ttgaacagct cctggagaga tgatcgtaga tttgatgtta ttttgccgtt gctcttgacg
    20881 taatccttcc atgattgcac ggacagcaaa ttttgttccg caataaacgg cggaatcagg
    20941 ataaacaaca tgtcccgcca cagaatcagt tgaaatgata tgcccagatt tttgtttttc
    21001 catgattgga agtacggcgg aaattccatt taacacaccc atgatgttga tatcaagcat
    21061 attttgccat tcatcacggt gaccttcaac taatggagcg gttggcatga ttcctgcatt
    21121 attgtacaat acatcgattc gaccgaactt ttccatcgct aaatcgataa ctgcttggac
    21181 ttgtgcaaaa tctcttacat ctgctgtttg aatatatagc tcagcttctg gtaaagattc
    21241 ttttattgct tttaggcgat cttctcggcg tgcagctata actagtttag cccctttttc
    21301 tgctaatagc ttcgttgttg cttcaccgat tccgcttgaa gcgcccatga tgacaatcac
    21361 tttttctgat aaatcattca ttctattctc ctcctgtttt gaaaaatctc ttgcttatac
    21421 tcactatctc ttatttcatc ttactgttca aataatccgt tcgacaggtt tgacgatttt
    21481 ggcagggatt cctgcaacga tggtattgtc tgggacatct ttcgtaacag ttgcattcgc
    21541 tgcaacaatg gcattctcgc caatcgttac gcctggcaga atagttgctc ctgctccgat
    21601 ccaagcattt ttcttgatgt ggattggctt tactgacaag cctcttcgtt cttttggatc
    21661 ggttagatgg ttcaccgtga tgaggttgac acgaggacca atcaatactg aatcttctaa
    21721 acagatgcca cctaagtcaa cgaacatcac ttgacgattg ataaagacat ttttccctat
    21781 actaatatgt ttgccgaaat ctgtataaaa aggcagcaga acagtcaccg tatcatctac
    21841 tttgtcacta atgatatttt ctagccgttt gcggatatct gctggttcat ggtacccagt
    21901 attcagcgct gctaaaggct cttcgttttc cgcttggatc tgatggatca cttcaaagag
    21961 cggatccgtt actcgaatct ctttattgac gatttgtttt tcgatgaggc ttgtcatttt
    22021 gctccctcct tttatcctta ctttataacg gacggcttat gatgtctaat acttataaaa
    22081 catacttaac tattcctttt aactatactt agtggtatgc ttttttaaaa acaggaggga
    22141 aaaaatggat attcgtatac tgacgtattt tttagcagta gctagagaaa aaaatatcag
    22201 ccgagcagca aaatctctgc atatcacgca acctactctc tcaaaacaac tgaaagattt
    22261 agaagaagaa cttggtgtga cacttttcac tcgaggctcc cgagagatac agttgacgga
    22321 ttctggtcga tatctttatt caaaaggaaa agaaatcttg tcgttggtag aaaaaacggc
    22381 gaacaattta acaaatgacg caatcatctc tggagaaatc tacattggcg gaggcgaaac
    22441 taaagcaatc tctttcattt ctgatagcct tcattcgttg atcaaggcgc atcctgatat
    22501 ccagtttcat ttatatagcg ggaatgcaga tgatatcata gacaaactgg atagcggatt
    22561 acttgatttt ggactcgtaa tcgaaccgac aaacaaacaa aaataccagt catttcgact
    22621 gccagcccaa gatcgttggg gacttttgat acatcggaat catcctttag caaagcaaac
    22681 agtcatccat ccgcaggaac tgaaaactgt tcctttgatc atttcccggc aaacgtcagt
    22741 ggacagtcaa ctagctgaat ggctaggttt cagcatagat cagttatcga tcgtcggaac
    22801 atataactta ttgtacaatg cttctttgat ggtcgataac gggacttttg gtgcattagc
    22861 tctagatggg atcatcaata cttatgggac ggaaaaagta ttcatcccac tcgatccgcc
    22921 attacaagct tcactgaatc tcatttggaa aaaagaccag cctctttctc ctgctgctcg
    22981 taaattttta gatgtcctaa cggagaaata cagttaagta gagttttttt ccttcgcttt
    23041 cagcttttta acaacgaata agttaagcaa aagatccaat gattaaataa cataagtttc
    23101 ttaatttgtt ccttcctttt atttctgata attccagtaa attactataa ttataaaaaa
    23161 agaattgaca aaacataact gtctatataa aattgattac gttaacaata attcgtttca
    23221 tgtgactaga tcatactagg catgaaaaat ctctgaggaa catggtttcc ctaggaggtt
    23281 tttcgtgtct atttttgttt ggccgcaatc aactggtcta gcaaacgtga aaaccaaatc
    23341 ttcaaaaagg gtgcgcgcat gaaaatcaaa aagatcttta atcaaaatgc agtattggta
    23401 gatgacggtg gacaggaaaa agtagctatt ggaaaaggga ttggatttga cagaaaaaga
    23461 aatgatttga tttttgatcg tgatgtcgaa cggatatttg tcatggaacc agaaggtcaa
    23521 atcaagttgc aaaatttact taatcagatt gatgaacgct ttttatttgc agcagaaacg
    23581 atcattgatc atgcggaaac tgttttgatg gaaaagttga atgaacatgt attgatcgct
    23641 ttgaccgacc acattgcttt ttctgcggag aacattaata acggtatcgt catccgcaac
    23701 aaacttttaa gagaaatcga agtgctttac agtgatgaat tcagtattgc tcaatgggca
    23761 gtagagtatc tgacaaaaga gcttgggatt ccatatactt atgacgaagc aggatatatc
    23821 gcaatccata ttcacagcgg acgaagcggt cggaacaata accatcgcag tatccgtgaa
    23881 gtgacgattg tatctgacat catccattta gtggaatcag aattggaaac agatatccat
    23941 tcagaaccat tttcactgaa ttattcaaga ctggtgaatc atttacgact gcttctacaa
    24001 cgaacccatg cgcaacaata tgctgtttta gacacggaaa tcgtagaaat ggtcaaacga
    24061 aaatacccag aaagctataa gatttctaaa aaaatccgtg tgttgctgac caaagaatac
    24121 cagctcgcga tcacgaaaga agaactgggt tacttggcca tccatatcga gcgtttaaga
    24181 agcgcaatcg tacaaacaaa tgttaacaat catgaggagg aaaaaaattg aaagcatatc
    24241 tacaacgaat gggacgttcc cttcaacttc cagttgcggt cttacctgct gctgctttac
    24301 tagtagggat cggaaactgg tgggcatctt atagtaacga cattgtcgct cattttttac
    24361 aagctggcgg taacgcagtt ttaggtcaat tacctttgct gtttgccgtt gggttagcac
    24421 tagggatgtc agtggacaaa tcaggtgctg ctgccttggc aggtttggtc gcatttgaag
    24481 ttccagtaaa tgttttaaaa actgattcag tagctacttt attgaatatc aaaccagaat
    24541 cagttgatcc atcttttgct cagatcagta acgtatttat tggtattatt gccggattga
    24601 ttgcggcagc tctttataat cgtttccacg aagcaaaatt accgatggct ttatctttct
    24661 ttagcggcaa gcgtctagtg ccaatcttgg ctgcctttgt catgttgctg atcagtgcag
    24721 tgctactgct cgtatggcct ccggtttact ctgctttagt ttcttttgct aaattcattt
    24781 tgagtttagg ctggggtggt gcaggtcttt atggcttctt caaccgttta ctgatcccta
    24841 caggattgca tcaagcaatg aactccgtgt tctggtttga cgtagcagga atcaatgata
    24901 ttggtaaatt tttggcttct gaaggaacaa aaggcgtaac aggaatgtat caagctggat
    24961 ttttcccaat catgatgttc gggcttccag caggagcata tgctatttac agaaatgcac
    25021 gtccagaaaa caaagcaaaa acagcttcct tgatgttagc agcagctttt gcttcattct
    25081 ttactggtgt aacagaacca cttgaattct catttatgtt cgttgcttgg ccattatatg
    25141 tcttgcatgc aattttcact gggatttctt tagcagtgag tgcattcttc cattggacag
    25201 caggatttgc ctttagtgcc ggatttgtcg attacttcct atctttgaaa aatccgattg
    25261 cgaatcagcc attgatgttg atcgtccaag gattagtaac agcagtgatt tactactttg
    25321 gctttaactt tgctatcaaa aaattccatc tgatgactcc tggccgcgag gaagcagatc
    25381 tttcagatga cgatactgca acgactaatt cagacaataa atatgcggca caagcaagca
    25441 aaatctacgc tgcattaggc ggagccgaca atgtaacttc gatcgataac tgtactacac
    25501 gccttcgttt gcaagtcaaa gatacaggcc tgatcgatca aaataaaatc aaagccactg
    25561 gcgtacctgg tatgaagatc atcgacggaa aaaatgcgca agtcatcgta ggtacagaag
    25621 tacaattcgt tgcagatgag atggcaaaac tacatggtgg tgctgcaaca cgacctgcac
    25681 aaacaaacac cgtggttaaa acagaaacat ttgccggtgg aacgatcgaa caagatattt
    25741 acgctatcgc aaatgggaaa ctgattccaa tcactgaagt ttcagatgat gtattcgcgg
    25801 aaaaaatgat gggtgacggc tatgctgtat taccagaaaa tggagaaatc ttctctccaa
    25861 tcgctggtac gatcacaaac attttcccaa cgaaacatgc tgtcggaatc caaacagatg
    25921 ctggtatcga agtcttgctt catatgggca tcaacactgt tgacttaaaa ggcgaaccat
    25981 tcactttata tgtaaaagaa ggtcaaaaag tcgcaagagg tcaattgatt gctttagttg
    26041 atcttgccgc tattcaatct gcaggcaaaa acacggatat ggtcgttgta ttcacaaatg
    26101 gcgacaaagt ccaaagctta gaaatcgaac ccgcacgtga tgtaaaagca aatgataaaa
    26161 tcggctctgt ttccaacaaa gcctgagcca tcgtcttccc cagacttttt tatcgataaa
    26221 caaacaggag ctgagacaaa aatcttgtct cagctccttt ttccgaataa aaacggcgtt
    26281 ctcctgccaa ctccgcggta ataagtccag ccaaacgtaa catatgaaga gctatttttt
    26341 atttgactct tcttattact tgatgcagaa cagctttttt acaacctctg ataaacggtg
    26401 ttcaaaaacc agtttatcgg tatgaagtca aatttatgca aaaatgtgga aagccatttt
    26461 cacaaaattt ttcttcatac tcaaaactaa tcggcttttt cacaacctct ttatacatta
    26521 ttcctgatcc aatatttctt ttaatgctgc ttcaagagaa gttaatggtt ttcccaatac
    26581 tttttctaaa tcatcagagg aaatagctaa ctgatccttt ttaatatcat gttggatcgc
    26641 taaaaacatg tcagctgctt cttgagggaa tccggcttct tttagatttt cgacaaacgc
    26701 tgcatcactt gcttcaataa tttctaactt tttacctgtc gcacgctcta atgccttggc
    26761 taattcttca tagtcagtta gattgccgga taattctaag atttctggag agtcactttc
    26821 tactagtact tttgctgcag cttctgcata ttcacgtttc aatgcccaac ctgtttttcc
    26881 atttcctgca gcataaacga attgaccagt ttttaaagcc tgcccaatga taggtaattc
    26941 attctctaca taccaattat tccgtaaaaa tgtatgggaa atacctgaat ccttaatcat
    27001 tttttcagtg aattggtgat ctggcgctaa tacactgatc gagtgatcgg catctgcaaa
    27061 acttgtataa gcgatataag ataccccagc tgcttgtgct gccttcacta cattcttatg
    27121 ttcggcttga cgatttcctg gaacgccaga gacaaaaagc aatcgatcta ttcctttcaa
    27181 cgcttctttc attgagtcta aatcatcata atcaccaata cgtatattaa atccagcttc
    27241 tttcagtgct tctccttttt cttcactacg tactagtaca tagatttcat tttgtggaac
    27301 catctttttt aagaattcca gcgcataacc accaaaacct ccagttgctc ctgttactaa
    27361 ataatgcata tttgccactc cctattcttt ttatttgtta agatttacag ctgtacattt
    27421 ataaattaca cctttatcat aaagagtgtg gtaagataag tcaagcaaaa aaaatgaaag
    27481 gatgacaact gatgaagtat tctctgcaat ttagtgatgc aatccatgta cttgcctata
    27541 ttgaaatgtt tcaagatacc cgatcacttt ctagtgagat gattgccagt agtatcgaaa
    27601 caaatgcagc aaatgtacgt aaaatcatga gtcagctcaa aaaatccggt ttgatcttta
    27661 caaaaaccgg aaaaccgcag ccttcccttg ccaaaagtcc agatcagatt tctttactag
    27721 atgtctatcg cagcatcgaa ggtaatacac agcttatcca agtcgatcca aaaacaaatc
    27781 caaattgcgt cgttggtgcg aatatccaag aagctttaga agaaagctac gctcggctgc
    27841 agaaaaaggc agaagaagaa atggctaaga tcacacttga tagtctgata cataaaatag
    27901 ccgttttgga aaaagaaaaa agaccagaaa acacaggcct cgtagagaga tttttataat
    27961 tctctctact gtgcctgcat ttttctgatc ggaatcgtct acataaattc ttttattctc
    28021 cgggggacaa aagccttgtc atgccccttt ttcctctcta atgctcaggt caaagcgctg
    28081 aagtcatgac gtcttgataa acggtgttca agtagctgac cctcggcatt agttctgaaa
    28141 aatgcaaaat atggaaagct atttcccatt tttcctctct aatgctcagg tcaaagcgct
    28201 actttcacga cctctatatt atcatggttt attgactacc ggtatccaga tttctcccat
    28261 atatttcccg ttggtaactc ccatttcgac tacagcattt ggacccccaa cataggcgta
    28321 atcttctact tctcttaaaa catgcccaaa ggccgtattc gtcaaatcat ttcttaattc
    28381 ttcaggcgat tctgctaaag cgattacaac aagatacgtt ccttttggga atgggatgat
    28441 tcgggtagtg tttggaacat cctgactcgt ttgaacaccg acatagtaca tcattttccc
    28501 gttatagggt tcgttgactg taaagaaata atgattttca gcagcttgtt tcaatgcatc
    28561 tattgttcca ttaccgataa ctttttgctc aaatgcttgt ttctctgcag ccaaaccgac
    28621 aaaatccgta ttgctactct tcaattccac accaataccc gtcaccgtaa aatctggttt
    28681 ttcttcgatc ctatactttg ccatttctcc caccctttct attatattaa gttcatctta
    28741 cataaaatta aagggaaatg acacgattac gctctttttt ctagggatat ttttattttt
    28801 taactatttt tttgctttca ctgcaatcca aatctcactg taaacattac tgaaatcctc
    28861 tccccatttt gtaaaagaga tctcgggagc ttcgactaac tcataatctg aagaaggaag
    28921 ccattctgca tagattttcc cccaagtatc ttgtaaagtt tggggaaatg gccctttatt
    28981 aggaaaaatg gcccaagtgt gttcttctat agcaagcatt tctaaatcag cgtacggatt
    29041 ttcttttgtc gtagcaaagc caatcatgtg catcaaactg cccttttctt ccaagcgggc
    29101 tccatcaaat ccataagaaa cgttgattac ttgatttgga tataaatctc ctaacttatg
    29161 catctcttcc ctttgagtct ccgtgatcgt ctgcgctaac ttttgtattt cttgattgac
    29221 tccttcaaat ttgacaggaa cttttttcgc cacacctgcc acataaaact gttctttctt
    29281 ttcgatacga aattccatcg attttcctcc tctgacatca ataaaaaatg tcaagcgtgg
    29341 aaaagatttt tgtatgccgt atctgctgat ttctgaaggc agatatcctg accaatcacg
    29401 aaaagctctt gaaaaacctt cgactgtttc atatccatat ctaaacgccg tttctgtcac
    29461 tcttgatcca tctaggagat cgcgattagc caaagccaat ctacggtttt tgatatagtc
    29521 cattagcgac atccctgcaa taaacgtaaa gatgcgtttt aattgatatt cagagattcc
    29581 tgtattttcg gctattattt tataggaaag tccttctgtc aaatgttctt cgatgtaatc
    29641 gatcaattgg ttcagatctt taagcatatt tatcttcctc cttgcttgcc tttttatcat
    29701 attatcaaag aaagtcaatt acttgatgaa tcaggaacca atttagtcag atgtagaaaa
    29761 tgttgtatgg atctaaagaa aattctcaag cagcgtttcg taacggataa ttggtattat
    29821 ctgcctatct atgttttacc tttagaaaaa taaattttgg ggaagacaca ttctaagtaa
    29881 acaaagcggt aaaaatatct tttattccct tagttaatcc gcttactacc tactgtacaa
    29941 agcaaattgt tgttcaaact gctgatcaga acgctgcttg gatttttctt tgcgatacat
    30001 catacctctt ttatcaattg gaacaattat ttatttctaa caaaatcact tcatttttgt
    30061 cagataaata aaaaacaaaa aaagttccat ctttaaaaca cgctattctt ttactttttc
    30121 tcacattctc taagaaaaga aaaggagaat gaatttttga caattcgagc aaaagtgatt
    30181 atcaaatatg taaaatcagc tacttttttc ttaaacgttt ctttatacta aatataaata
    30241 agtgtttcat gaaaggagaa ctagatgaat aattggcttg agtattttcc tgaaaacgtt
    30301 ttggaacgcg gttacagcta tcatctgcac ggttttgtcc gtcatttgaa ctatacaagc
    30361 aagtacttgt ccgcaacagt ttctggcacg gaagattata aggtagtgat cacttgggat
    30421 gaaaagacca acatgacttg tgattgtcta tatgccatag aaggaaaaaa atgcaaacac
    30481 atggctgctg tcttattcgc ttacgaagaa cgtccaataa aaaaatccaa ctactcactt
    30541 tccgaactct cgtcccttgt ttcctccgct agttcctctc ttgtacggga gcttttaaca
    30601 gagattctta tagaacatcc gcaatttatc gaacgcttca aagttaagat gccatttcat
    30661 gcaataaatt attcagataa attaacaact atcatccata aatacgatca tattatcaag
    30721 aaaaacaaaa acaggaaaac agcgaagttc atcatggaga tgcgaaagtt catccaagaa
    30781 gcagttgaat cgctcattca gcaaaatgcc tatcttcccg cattcgaatt gatcaatgaa
    30841 gtgattgcta ctctcgaaac attctattgg gagcctgagg atgaacgaac ccttcttctg
    30901 atagaggact gttattattt atggaaagaa ttattagcag aagcacctca tgcagaaaaa
    30961 aggcaaatgt tctcttggtt cgtctgccaa gtcgatcata ctgacgcctc ttattcaaaa
    31021 cgctactcca taaaaatcct gaaagaagac tttcgggaaa aagaattttc taaccaaaag
    31081 aaaaaaatag ataaaaaaac taaagaaacg gtaaagaaag acgatttcaa tgaaaaatag
    31141 caagtaaacg ataacaacca tcctaaatcc acaagaaata cagcagacct tgctttaaaa
    31201 acacgaatca tgcaaaggat gaagtaaaga agacttaacg cgtacccaat attagtcatt
    31261 tgactattag gtacgcgttt tgttttataa gtcatgacaa atttccttcg ttgctgggta
    31321 gattttccgg cattgttgat agattttatg atacttttct acattttgta agagaggttc
    31381 cactgcatct gtatattgga taaaattctg acaacaactt tcaggtgtgt cgaaccactc
    31441 taatctttaa agataaatat taaaataacg attaataata ttaacagtct ttatttttca
    31501 ccaccaaaaa cctatctttg catatactaa atagacgtat atacacagat aggtttgtct
    31561 tgtgaaaaat aatgattatc cttaccaaaa aatgtttgtt tttctacatg ttcgtactta
    31621 tcaaaaaata tgatccttat tgaaattact ggctatttat attccaacga cttcttgtgt
    31681 taatttttgt tatctcatag taaattatgt ttcattttca cttaatttag ttgtcacgtg
    31741 ttcgtcaatt cgtaaaaacg gtaaatatat aaacacactt gcggctataa ttaatatttg
    31801 taaaacagct gctcgccagt ctccggctgt tgctaaaaat cccgatataa ctggtggcgt
    31861 agtccaagga atttgcacta ctacatgatt aattaatccc acagcagttg caaaatatgc
    31921 tactgtcaaa gaaaaaatcg gtgcaagcac aaagggaata atcagactga tattaaatac
    31981 aataggcaat ccaaaaataa taggttcgct tatattgaat atagcgggag ttaccgataa
    32041 tttagcaaag tccttataat cttttctacg actgaagata aatattgcaa tcaataaagc
    32101 aatcgtattt cccgatccac ccattaccgc aaaggtatct ttaaaggcca tattgataat
    32161 atgtggaatt tgctctttgt ttgcataagc tgccatattt tcttgcatat tctgaatcaa
    32221 aaacggatct aacaatgaac ctgatattac tgcttgatgg ataccaaatc caaaaaatag
    32281 attagcaata gatgtaatta acaaaaatcc tggtaaacca gttgtaattt tacttaatgg
    32341 ctctgtaact atcgtggtaa ttagcttatt tatatccata ttaaacaatt gaatgattat
    32401 aaatgacaat aaagcaaacg aggtaatcgt aataatgatt gggattaata cattaaaaga
    32461 ctttaaaaca gcgggaggaa tatttccgga tagctgaatc tgtagtttct tattattaga
    32521 aagtttaata aataattctg tagccgctaa tccaacaaat atacctacaa acattcctga
    32581 agctcctgta taggatatag gtatcacacc cgtcacttca acagctttat ccgcattttc
    32641 aggagtaaac atcatctgca taggtgttaa tacaacaaat gtcgaaatag caactaatac
    32701 cgctgcaata tgatttgtat aatttctgct tgcacacata tgataagata ctgctgctac
    32761 aactaataat gtagttatgc ttaatgtacc attggcaatt gaagtaccaa tttgttgtaa
    32821 cgtggtcaat gtactagtat cgacaatttc ccccatgaat cctgttggtt ctaagatcac
    32881 tgaattaata agtgtcacaa atcctgctaa catcataaat ggcataaatg tagcaaacgc
    32941 atctcgcaaa gttcttaaat ggatctgatt ccccaactta gtcgcaacta taccaaattt
    33001 ttcaaataca atgtccttcc tgctactttt gcccatattt tttctccttt atgcttattg
    33061 taatcgatta ctttttccac ccaaataata catcacttat caaaaaaagt aaatactttt
    33121 aattaaatat atatatcttt tttagtataa aaaaataagc tctgaaaaaa taattttccc
    33181 gagcttattt ttcaacaaaa acagcttcaa aaacaaagtc ttgatataaa tgtctcgata
    33241 ccgaatactc gaaaggttta ccagacgata gagcaacaac tttgtctatc tcaatcataa
    33301 attcacctgg atctattttt aatatttttg cgtcaaattc attcgcagta tctcctttga
    33361 tacgtatgtg cgaagtcttt atttccagac ccagttcatt tgtgatataa gcatatacag
    33421 atttctttaa atgttttggt tccaagcctg gtatgactgc taatggcatg aatgtttgct
    33481 caatcgagta tggttgacaa tcaataaaac ggcttcgtac aatattatat acatagtctt
    33541 ttacactgat acttaattta tcagctactt ttttcgatgg aagttcaatt gagaaagtat
    33601 ggatttctga atctacgtgt tcttcaccaa ccacgctaaa caaaccttcg tttggaccaa
    33661 gaactcgtga gttatcaatt ggtgttctga cgacttcagt cccataccca cttctacttc
    33721 gcaaaactcc ttcggaaaca agtaagtcta cgcctttctt tactgttaac ttgcttgtat
    33781 gataaataac tgccaattca tctcctgtag gaagtttctc accaatttta tactctccat
    33841 ttacaatttt tttctttata tctaagtaaa tttccatata cttcgcaatt tttttcaatg
    33901 gtgaccctcc aatcaaaaac atatcttcat ctatacttta acataaataa accgataaaa
    33961 tccacatcaa aattatacac acaataaaaa agatatatat atttaaacaa aactatttac
    34021 tttaagttgt aagcggtgtt atcattaagt ggaaacagga ggtaaaaaaa ttatgacaac
    34081 tatgaaaaag ctaacttttc cagatgattt ttggtggggt tccgcttggt cagctgagca
    34141 agcagaagga aaaggagaaa caggaaaagc agagactatc tgggatcgct ggtttaaaga
    34201 acaaccttac cggttttatc aacgaatcga ttcctctatt acaaccgatc acatccatca
    34261 atataaagaa gatatagaac taatgaaaaa aactgggcat aactcctttc gcgtttctat
    34321 ttcttgggca cgaatgtttc caaatggcgg taccggaaaa gtaaatccca aagccatttc
    34381 tttctatcga aaattatttt ccgaaatgaa taataacgga atcaaagtat ttgccaactt
    34441 atatcatttt gacatgcctg ctactcttca agataaagga ggatgggaat cacgtgaagt
    34501 agttgatgct tatgttcatt acgctgaaac ttgttttaaa gaatttggtg acttagtttg
    34561 tcattggttt accttcaatg aaccacttgg gcctatttta ggtacttatc ttgaagattt
    34621 tcattatcca aacctcattg actttaaacg cggagcgcaa gcagcattct tcactatact
    34681 tgcacacgca aaagcaatac aagtatttaa agaactagct cttcctagta aaataggcgt
    34741 tattctaaat ttgagtccta cttttcctcg tagtcaaaat cctgctgatg tgaaagcagc
    34801 agaaatcgct gatttatttt atacgcggag ctttttagat cctatggtta aagggaattt
    34861 ttctaaaaag cttatcctgt tattacaaga atataatcag cttcctgaag attatacgaa
    34921 agaagatctt gtatgtatct acgaaaatac cgctcaaatt cttggactaa actattacga
    34981 gccacgtcgc gtcaaatctc gttcttctat ggtggataca tctagtccat ttttaccaga
    35041 gtggtttttc gaaccacata tcatgcctgg acgacgaatg aacgaatacc ggggatggga
    35101 aatttacgaa aaaggaattt atgatttgtg catggatatc aagaaccatt atggaaacat
    35161 cgaagcattt atctcggaga acggaatggg cgttgcggat gaagaacgtt tcatggatga
    35221 tacagggcaa ataattgatg attatcggat tgagtatatc aaagatcatc ttgcttactt
    35281 atggaaggca ataaatgaag gatgtaacat taaggggtat catctttgga catttattga
    35341 ttgctggtca tggatcaacg cctataaaaa ccgatatggg ctggtttcac tcgaccttac
    35401 tactcaaaaa agaacaatta aaaaaagtgg cgaattttac aagcaattaa gtgatacaaa
    35461 tggatttaga tacgatgtag acttgttagt tgaataatat tctaaaattc cacttgaagt
    35521 gaacacatta gaaaacaaga ataatgagaa ataccaataa caaatacttt ttcttcatac
    35581 ttcatttata cttgtcagta taagagactg tgacaaatgt agtgatcctc agaagttagg
    35641 tctggaaatc taacttgaga agattttttt aaactacgtc cagtcttttt tatttgttta
    35701 aaattgaagt tgacaagtct tcattaaaaa tttagaatat tcacaagttt gacgacaatt
    35761 atgaaaattt atgtcgtgct aaaggagttt tgttattgga tgaaaagtta gatataaaaa
    35821 ctgcgatcaa agacacgtta cctaccgttt ttggttatat cggtattgga cttgcatttg
    35881 gtatcgttgg gaaagctgcc gggtttcatc cgctggtcgt cacgttgatg tccctgctga
    35941 tctatgctgg ttctgcccaa tttatcacgg tcagcatgct tgctagccat agtccactgc
    36001 tctccatcgt tctctcgacc tttctagtca attcccgaat gattctgatg agtatgacga
    36061 ttgctcctta tttcaagaaa aatcggctgc ttcaaaatct gctgattggc acattgctga
    36121 cagatgaaag tttcgcactg ggaatgaata aattgaacta tactggacaa aagttaaact
    36181 ttcgttggat gaatacagct aattggattt cttatttgac gtgggtgggt tcttctcttg
    36241 ttggcgcact tttagggaat tttattactg atccgaaaaa gtttggtttg gatttcgcca
    36301 tcgtcgctat gtttatcggg ttactttatc ttcaagtcat ttctgataga aacacctcta
    36361 aacgattaca gttgatcctg attggtctca ctttgattct ggtatatgtc ggactgattt
    36421 ttatcccaag taacttagtg attttagttg taacactgat tgggtgcgga ttgggggtgt
    36481 ggatcaaaca tgccttcttt tgagtttaca ttgctgacta ttttaggttg tactttagca
    36541 acttggcttt ctaggatcct accatttgtc ttactgaaaa aattcgattt gccgcaaccg
    36601 ttgcttgagt atttaagttt tgtcccgatc gtcattatgt ctgctttatg gttcagcagt
    36661 ctatttaccc aaaatatcgg acatctgccg cagatcaatc tcgaaaatgc tttggcttca
    36721 gttcctacac ttttagctgc tattctttca aaaagcttat tggtgatcgt cttggtagga
    36781 attctttccc tttcgttgat tcgcttatta taaataaaaa aacaagagct tatggcaaat
    36841 tactgtcatg cgctcttgtt tttatcaaag tcaaataaga aaaaaatcgg cgtattcttg
    36901 cttatccgtt gaacggacca ctaacaacga cttttcctaa tatatgtcct gtttctacgt
    36961 ctttggttgc ttgtttcaag ttcttcgcat tcatcccatc tgaatagacc ttgctcaatg
    37021 tactgcggat aatcccttca tttgctaaag cagcaatgtg cgctaaagct tctccttgcg
    37081 tttcgatttc atagttatag tctgttttag cgaacatata ctcccagtcg aagctgatag
    37141 attggttttt ccaaacacct atatctaacg gctctttgat ccctacgatc gttcccacat
    37201 gtccaaatgg tcggacaagg tgtttgattt gatcaaagta gcgggtaata tcgaataata
    37261 cagcgacata ctctacttga tcgattccta attcacgaaa acttttactt aagtcgtgat
    37321 gataatcgat tggatagtct acacctgttt ttttcagcca ttcaaaattc ttcggacttg
    37381 cagtcgcgta gacttctagg ccagcccaat gcgctagttg attcaaaatc gaaccgacgc
    37441 ccccagctcc gttgatcact aagatttttt tcccgcggtt ggcattttct tctggagtca
    37501 gaccaaattt ttcaaataac aattcataag cggtcaatga ggtcaacggc aaggctgcgg
    37561 cttcttcatc tgaaagattt tttggtgcaa gagcgacaat acgttcgtca accagttggt
    37621 attcttgatt gcttcctgct cttgtcgttg tacctgcgta aaaaacgcga tcgccgacag
    37681 aaaatttttg cacttcatca cctacagcaa caactttccc gactccatca aaccctaaga
    37741 tacgtaaagc atttcttatc ccgttatctt ggcgaagttt cgtatcgaca ggattaacag
    37801 atactgcgtt gacttttacc agaagatccc gtgaactggg tacaggtatc tgttcttttt
    37861 catcaataaa gctttttgga tcatcgatcg acaacccttc ataaaaaccg actaccttca
    37921 ttaattcctt ttctgacata cgaattcctc cttagcttca tcaagttgga gcatccatac
    37981 agttttcatt tcaatatata tagtatgcta tttgttccac ttttattcat cataattatt
    38041 ctcttactta aagtaaacta tttgcacttt tttggttaaa aaagaggttg cgacaagact
    38101 tttgtcacaa cctcttttaa acggtgttca atcaactgac cctcggtatt cgctcaaaaa
    38161 acgacaaaat atgaggagct atttttgttt ggctgttctt attacttgat gcaggacagc
    38221 tttttcacga cctctaattc acggtgttca agcaagaaat cattgttcac tgaaaagcgt
    38281 tggatgttct ttttcaaagg tgtctaagat ctctcgtact tcatcagtag atttcgtatt
    38341 catcaactga actcgcaagt catttgctcc tggaaatcct ttgatataga ttttaaagaa
    38401 acgatgtagt cctgtgatgg aacgcgggat gatttctgaa taatgatctt gcagatctag
    38461 ttgcagacga agtagtccga tcagttcttt ttctgtatgt tccctcggtt ctttttcaaa
    38521 tgcataagga ttcttgaaaa tcccccggcc aatcatgatg ccatctacgc catatttttc
    38581 ggccaattct tctcctgtct ggcgatctgg gatatctccg ttgatcgtga tcagtgtttg
    38641 cggagcgatt tggtcacgta aagcaatgat tttagggatg acttcccaat gtgcatctac
    38701 tttactcatc tctttacgcg tacgcaaatg gacagaaaga ttggctatat cttgatgaag
    38761 taggtgactg atccattctt ccatctcaga catttccgta tagccgatac gcgtcttgac
    38821 gctgacaggc aaaccgccag ctttagccgc ttcaatcaat tgtgccgcta cttctgggcg
    38881 aaggatcaag ccactgcctt ttccacgttc tgctacatta gggactgggc agcccatgtt
    38941 gatatcgatt ccttggaagc ccatttctgc catagcaatg ctcatttctc taaaaaattc
    39001 tggcttgtct ccccaaatat gggcaaccat cggctgttca tcttctgtaa aggtcaatct
    39061 tcctcgtaca ctgtcttttc catctggatg acagaaactg tctgagtttg taaactcagt
    39121 aaagaagaca tccggtgctg ctgcatgctt tacgacatgg cgaaatacaa catctgttac
    39181 atcttccatt ggtgctaaaa caaaaaaagg ctttggcagc tctttccaaa aattagtagt
    39241 catttatttg ttactctcca ttctatcaag cagtgaagtc gcaatctttc tcaaaaacat
    39301 tgtcattata ctaggaaaca aaaaaagaag caaagtgaac agcttaaaag atgtttctga
    39361 ttgagcaaaa aaagactgtg acaaaaatct tatcacaatt ccttttccgg aataaatggt
    39421 gttcaaaagc ttgcatctgc ggtaataagt ccaaccaaac gaaaaatagg aggagctatt
    39481 tttgtttggc tgttcttatt acttgatgca gaacagcttt ttcacaacct ctccactaaa
    39541 cggtgttcaa tcagctgacc ctcggtatta gctcaacaaa cgacaaaata tgaggaacta
    39601 ttttcccgtt tgtttctcta atactcaggt caaaacgctg atttcacaac ctcttttcta
    39661 acttctcaat cctcttcctt tattgatcaa ataccaagta acggcgtaca aaacaacgat
    39721 gaatagcaca agtacgatca tcgatgttgc tactggcaca tcgattgttc caaggaatcc
    39781 gtaacggaaa ccggagatca tataaacgat cggattgact ttcgaaacag cttgccaaaa
    39841 tggcggcaac atagagatgg catagaaaac gccacctaga taagttaacg gctgcaagac
    39901 aaatgtaggc acgatcgata catcgtcata agactgagca aaaatcccgt tgagcagtcc
    39961 tgctaacgaa aacaagattg ccgtcatcaa taatgtaatg atgaccatga accatgaata
    40021 cacatgaagt ggtacaaaga acaaggaaat gatcgttacg agagagccga cgagaatact
    40081 gcgacccact ccgccaatca caaagcccca aatgatcaca tgcgtaggaa caggcgctac
    40141 caagatttct tcgatgtttt tctggaattt ttgagagaag aaggacgaag aaacgttggc
    40201 atacgaacta gtgatagcag acatcataat caaaccaggc acgatgaatt ccatatatga
    40261 aaaaccaccc atgtcaccga tccgaccacc gatcattttt ccgaaaataa caaagtacaa
    40321 ggatgtcgtg atcacaggcg gaaccagtgt ttggacccag atacgcaaat agcggttcgt
    40381 ttccttgata gctaaacttt ttaatgcagt aaaataaaga ttaaacattt ttctcctccg
    40441 tatgattatt ttcttctgtg attttcaaaa acagttcttc taaacgattc gacttattcc
    40501 tcatagaaag aactttgatt ccttgtcttg tcagctgatc gaagattccg ttcacccctt
    40561 gatttcgttc aacttcgaca gcgattgtct gttcatcttc aaatgtacaa gcgtatcctt
    40621 caatcacagg tttggtctca tatggcgcta aatcaaagat aaatgtttca aattgcagtt
    40681 tggatagaag ctctttcata ctagtattct cgatcagttc acctgattgg atgatcccga
    40741 tgttgcgaca aagcatttca gcttcttcta aataatgcgt cgtcaaaatg atcgttgtac
    40801 cattttcgtt caattctcgg agaaactccc acatctcgcg tctcaattca atatcgactc
    40861 ctgctgttgg ttcatccaag atcagcaaac gtggttcatg catcaatgcc ctagcaatca
    40921 tcagtcttcg cttcattccc ccggaaagca tacgtgcacg gacatttctc ttttcccaaa
    40981 gattggactg cttcaaatat ttttcgctgc gtttcatcgc ttctttgcga gagacaccgt
    41041 agtagcctgc ttgattcacg acgatttgct ggaccgtttc aaagggattg aaattgaact
    41101 cttgcgggac taatccaatc tgttgctttg ctcggactag atccgtatcc agatcataac
    41161 cgaagacatt cacttttcca gatgttttat tgactaaaga agtaatgatt ccgatcgttg
    41221 tagacttccc agctccattt ggtcctaata gcgcatagaa atctccttct ttcacggaaa
    41281 gatcgattcc tcgcaatgct tcgaccccac ttccataaac ctttttcaaa ttatttattt
    41341 caagcgcatt tgccatttat ttcctatctc cttatagaca tgattcttta ttgtatcatg
    41401 gaatacagca gatgaaaaaa caacttggtt ccagcgaaaa atcaggttgc tgggctcagg
    41461 aaaatctcct aatgaaagac atcaatcgga cgaagtcaga caaccttttc agaaaaaaca
    41521 aatcgaagat aaaggattac tattcatatg tgcaacaaaa ggagcgtgag acaaaagtaa
    41581 agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcaaaa gccaagattt
    41641 ttgatccaat aaatactttc gatcacttcg cctatcccaa tacatgccac tgccgctttt
    41701 catcaaataa cgcggcttcc gtttttgcgg tttctactaa agtctctggg taatccaaaa
    41761 ctttcagcaa ggcaatcgca tttcgggtcc ttgaaggtcc ttcttttaat ttgaaatcaa
    41821 aactgattcc ttttccttct gttacttgtt cttcaaagtg gacattctca caataattct
    41881 ttaaaatctc tgtcaattcg atatcatgtg tggcgacaaa tgctaaagat ggatactccg
    41941 caagccaccg aacgactgaa gcggaagaag caatccgttc gatcgtattt gtccctttta
    42001 aaatctcatc tacgaagcag tagcagcgtt ctttggaagc cacttggtcc aacaaacgtt
    42061 tgatcgattt gatttctgaa acaaaataac tgtcgccttc aaataaatca tcttcgattg
    42121 ccatggaagt caacacatgt ccaggttgca gggtaaactg ttctgcaatc gctgtttgga
    42181 tcgtctgtgc tagaatacag ctgatggcta tacttttgac atacgtagat tttcctgatg
    42241 cattggaacc cgtgactaat gtattcttct gccagttgac cggattcact accgcttctt
    42301 ttaacaatgg atgatagata tctttcgctg tcacaccgcc ctcagtaaac tctggtcggc
    42361 aagtgatggg catataagta cggtaattca atattgcagc ggctacttct aattctccca
    42421 gcaattccca cagcttgatg gcttcagttg aatgcttttc taatttagtg agaacgaaat
    42481 gataggagat aaatggcagc atgaacatga tgttgacata ttcaaaaatc aactctgctt
    42541 cactcccact cttcatacga aatgaaaaac ctaatttagg gatgtctctt aatggtttag
    42601 tttgctgttt cagctcttct tgaagtggtg tcggcagttt tgctagctga ttggcggctg
    42661 aaatcgttga aaccaaataa ctcatgctat tcagctctgt ttctagtgtt tgtttcttca
    42721 ctagataata gaccgtattg aatactaacc caccgattgc caaatagatt cctagtactt
    42781 gtcctaaaag aagcaaaccc aaacccacca gcggaagcaa gccaagaaaa ataaataaac
    42841 ctacgcgtcc aatcttttta ctttttccat ccgctagata ttgttttgca aaattatgat
    42901 ctttttttcc taaacgagcg aattgatatt ggattttttc tctcagttga ggattttcct
    42961 gataaaaagc aatcagtttt tctaactgct gatcttcacc aaaatcaaag ctgcgtaaac
    43021 gttgatacaa cgcttctgaa cctacactag aataggtact gttgattcct tcgaatactt
    43081 cgaacatatc caggtcatac caagtaagat catcgatttc gctatcccat gaacggaact
    43141 tcttctccgt gagccatgct tccttcaagc tttcttcttt atcaaatctc ggttgataag
    43201 gaattttttc ccatttgcta cgaactgttt cctttaattt caaacgtgaa aaaatgtcta
    43261 aagcaactaa taaaataaca gctgcaataa taattaaaac gataaattct ctttgaccca
    43321 tatccctctc cgttccttta tttgttagct ttagtatagc actgttgcgc tatttgaaaa
    43381 gagggtaaaa aaacaccttt caaaataaaa ggtgtttttt tcttgtatat tacatattta
    43441 tctctcattt atcaaaattg acaaataatc atagggagga attgttgtta attcttgttt
    43501 attctccagt gcattgacaa ctgtcccaag ggaaaggata gcctcaggta ctattttttc
    43561 ttgttctgtt ggattagcta agcgaagaac aaatccttgt tcatgaaaat aagaaggata
    43621 aatcgatgat acaattaagt cttcaggtaa ttcaatcaat gaaaatttac gaggaacatc
    43681 aagttcattt tgtaatggcc aaatcttgtt atctaacctg tgaataaata cattcagttt
    43741 ctgcttttga taagaaatag attgttctaa ccgtttttct gcctgttttg ccactttgaa
    43801 ctcattaaat cttccttctt ctacattaaa tccaaaagtg actttatact cacctatctc
    43861 ttgagctagc ggtgtttcca tcatgacatg cccttcattt gtcgtatctc ctgaagctcg
    43921 cccaggtcgc caagcaagat taggttttcc aagttcccct gttgttgaaa ataaggttat
    43981 gattaattga ttttctatac gttcatactc ttttaaacca tctgcataaa acgtaaaata
    44041 atgatcattt tctgccacag agacactctt atcgaatatt tctaaattaa caggtttctc
    44101 taccatagtt tctgaccaat tcggaggaat gacatcaggg gtattttcaa taaatccgtt
    44161 ttgaatttgt gcaattgatt tttcagattt atctaaaaca ttaattgcta agcgcatacg
    44221 atgcgagtaa acagtattat gaattttgag tgtgccttca acgatttgac tttctcccag
    44281 actgaacgat atttcataag atatttcttc catttcgggt ttttcagata aacgatcttt
    44341 taaatcttta ggaagttgag cttttccgta aacaactaat gtttcttgta aagaatcttt
    44401 atatacttta gctgtttcta attttagaga tagttctgta tctccttcta atggtgaata
    44461 atcatacgta tcgccatcat ttgctgaatc gatcaaatga acgaaatcaa gatattgtct
    44521 atctccaact atcaaattca attgcccatc tttaaaagaa agtttatatt tattgttact
    44581 tatctcagtt ttgtctatct cgattgctgt ttctaatttt tcattatttt tctcaaattc
    44641 aacaacagtg tatcctagtg ctggcacatt tacatttatt tttatgtcaa gttcataata
    44701 agctggttca tcaaaatatt cgaaacctgt agcaatcatc cgataagcat ttttccgttc
    44761 tggaaaataa acttcttttt caatgatatt atagggacta cctttgaagt gtattttctt
    44821 tgaatcagct actacatgca cgattttcga tccactataa ttctcagtcg ttgtgttgaa
    44881 aacaaggact tcattcgatt ttagctttaa tgcatcagcc atccgtttta caataaggtt
    44941 ttcgattccg tcagctatct cattagcttc tttgattcga tggaaaatat cttccgcaac
    45001 attatctgaa acacagccac caatactatc atgagcctgg ttttgcaaaa tctttttcca
    45061 taaccgacga agtaggcctt tactgatatg gataccattt ctttctgcaa tcagcatgag
    45121 cggctcaact cgttttagaa ttttttgttc caatttaaaa ttttctattt tcatttttgt
    45181 tcttactgag ccaatagaac gatgaacacg agagtaaacc ggctgacgaa gttcaccttt
    45241 atattcaggt aattcttttt tgtttctgat aacttctaca taagaaggat aatctgaaat
    45301 aatattgtgg aatttactgt atttattcaa cttctctacg acttgatcaa aatttaaaat
    45361 cattgacttt tgatctacac ccgaaggtac taaaatatct ttgttttttc cttgcatatg
    45421 aagcatttca actgcttcat ccaacttttc ttttgcaaat tcaggaatat ctttaattgc
    45481 gtctaaggtc atcattccag tcatataacc aaatggaaaa ttcatggcat aaacaaattt
    45541 atctcccaat cctttccaga taaaataagg agatggaacc atcgtttcaa agtttaatcc
    45601 tcgccaacac atgaaattat cgatttctac ttgatgcaaa agtgtaggca aattcgcatt
    45661 gaacccaaac gtgtcaggca aataccctac catcattgga tctccatatt taaggatcgt
    45721 atcactgatt ccaatcatta agtttcttaa aattgattca gcatccacta ataaggcatc
    45781 tgtttgtgca taccacggtc ccacgaatag ttgtcctgtt ttcatcagtc gttggataac
    45841 cttaagcttt tgcggattga tctccaaata ctcatcgacg attgaagttt gtccatctaa
    45901 acaaaagttt actttagggt tcctttccaa ttcatctaga acttcagtaa agacctgatc
    45961 agacaatacg atggcatctt catttgtaaa ataccattct ctgtcccagt gcgtgtgttg
    46021 aattatatgt gcatttacca tatcagattc tcctactttc cttcttctac tgaatttact
    46081 tgttgttctt ttttatactt gatggatttt agtgcattga ccattaacgc tgtaaccact
    46141 cccccaataa caattgatac taaatataaa ggtatattcg taacaaaagg aattgccata
    46201 aaggttgaaa gcattgtttc ttgagtaaca ccaaaaaatc catttagacc acatgctact
    46261 gcagtgccca ccacgatgct tggtattact cgtaaaggat ctttcacggc aaacgggatc
    46321 gtcccttcag taatccccac aaggcccata atcatagctg tctttgcatt atctcgttcc
    46381 gattcatcat aaagtttttt gtttaaaatt gttgctaaaa acattccaaa tggcggaata
    46441 gcaattccta ataacatggc tgtactaggt ccaaagcttc cgcttgaaaa agaagcaacc
    46501 ccaaaagcat atgcgatttt attgataggt cctcccatat caaacgccat cattcctcct
    46561 aaaatagccg acatcaaagc agcatttgct cctgacatgc cttctagcca attagtcagt
    46621 cctgttgtca ttgcttgaat aggcgtagct agtacatacc ataatatgat tccaacaact
    46681 aatgtagtaa caaaaggaat cagcataatt gattttagac taataacttg catcggtact
    46741 tttacttttt tcaatgcatt agctaaatag ccacaagcta atccagcaac cattcctcca
    46801 ataaatccca taccaagatt ttgacacatc atcccagtga taaaagctgg tgctagaccg
    46861 ggacggtcag caattgaata tgcgatatag gctgaaatca tcggtacgat aaactgtaat
    46921 cccgtctgac caatcattcg caggactccc cagaatgtat ccgtctggtc ccaaacacct
    46981 gtgccaccaa aaatgactgc aatagaagtt agtaaccctg ctgctacgac aagcgggatc
    47041 atataggaaa ccccactttg gaaatgattt agaatttctc ttccttgttt cttgaattcc
    47101 attagtaact cccccacgat atatttttta tttgttaatt aatgcaattg cttcatcaat
    47161 cgtctcttca ccatctttta ctacctctga ggtccctact gttaaaatcg gtttaccgtc
    47221 aaagcgacct cgttctgaaa catttgtatc tactgcaaat atgacaacat ctgcctcgga
    47281 aacatccgaa attgaaagtt tgttttctat ccccatagcc ccctgtgttt ctactttaat
    47341 atctaaccct ttcttcttcg caaacttttc taaattagct tttgccatat aagtatgggc
    47401 aatccctgcg atacatgctg ttactgctac tatttttgtc atatgaaatt cctcctttta
    47461 aaatgataga gcttttacca attctttttt atttctcgaa tcttttattc ttttaacaaa
    47521 ctcgtcatcc atcaatcttc cagataattc tgctaaaata cgtaaatgat tagtaccttt
    47581 atcagtgtct tttattgcta acaaaaagac gagatcaact ggttgatcat ctaatgcgcc
    47641 ccattcaaca gaccgcttta acttggctac agccactgtt gattcaatta ctgctaggct
    47701 tttgccatga ggaatggcga tatttttccc aattcctgtg gtcatatggt tttctctgtc
    47761 aaatacgtct ttttgaaatt gtttgtggtc agacacaaac ccattagtct ctaacaattt
    47821 cgataatttt tcgactacac tttttttatc agatgcattt aaatctatca ctatattatt
    47881 tatattgatt ttttcactga tcatttataa gccttctttc aatatataaa ctaatttttc
    47941 aaacgacgaa ctcgttttta aatttgctaa taactcatga ttcgaagcga tttcattgaa
    48001 tgtttcataa attttattca attcaggttt tactttttca ttaagtgcaa aaaagaaaac
    48061 agaatgaaca agtgtcccat cccaatcaat tccttctgga ttaacgtaga cacagattac
    48121 tggctttttt ataaaatcta cttcgatatg cggcatagca aaatcattca tcgctgttga
    48181 agatagtttt tctcttttga ttgctccctc tagtatccct tctttcgcgt aattttcttt
    48241 taccaatttt ttggtaatta tatttaaaac gttcacttga ttatccttta tttggtgggt
    48301 aaaaaagcaa aatcgtttat ctaataaatt tagaaaagca tcttctgttt gttcatttaa
    48361 ctgtagatac tgttttactt ttctgacatc tgcccctaac atcaaaggac taacaacaat
    48421 aacaggaaaa tttgtatttt caatcggaat cgtgcttata acaagttcat cagtgacttt
    48481 tctatcttgt agttcattga tgcttagtac atcttctatc tcaaccatat ctgcaaaacc
    48541 gttatttatt ctttgctcta ataattttga tgttccatat ccgctactac aaactaatat
    48601 cactttcgtt ttgtcaggtt tgtaacgatc caaaagtgat tgaatatgga gtgttacgta
    48661 agcgatttca tcttcattaa aatgtataca gaatctctct tcgatttcct ctaataaatc
    48721 tacacttatc ataaatgacc ttttaaaaga atatttgatt ttgtccgtat aagggttata
    48781 gatatttact cccaatttga gtcttttaac tgctgcattg agatgtaata ctagattatt
    48841 gatcaattct tcatcaggat aaaattcatt taatttaatt cttactaact cttgtagctc
    48901 aacacccata tctaaatagg aaagcttcgt ttgatctaag tcgtgattca tagcattttt
    48961 ttcaatcgaa gtaatgtgaa tgtcaacata agcttgttca tctattggca caataattga
    49021 aaatgctttt tcaatcattt tgattaaaat aagtgtattc tttgagattt cttcttcaga
    49081 attattacta cgtgataaga aattgcttgt ttcaatcctt tctatcgcaa tagcaaggtg
    49141 gatagctaaa gtttgaaatt cataatctgt aaatttcaat tgtgtcttat tcatgtatcg
    49201 attaagcaat tcggctactt ttttcaatat gtccttattt aagaaattat tcgcttcacc
    49261 aatgaaattg atattcaagt ctaagagatc tgttttactg ttagatgctg taaagccacc
    49321 ccaataatag ttcacaactt ctgacatcaa ccttctttta cttttttcat cagctttgat
    49381 gcgcacgcca tttcgatctg aaactaagga catcccatgc ttgtttagtc tttttctaac
    49441 atctttcatt gtgctttcta ccgtcgacct gctcacgtat aattcgtcag caagattttg
    49501 aatctttaga gaatcattag tattcaataa tttagcaaac acataagtta gacggtcctc
    49561 cggagagtct gcgatattga ttttatgact ggataataaa tttcgaagtg tttctttttt
    49621 tccaataagc gaaacgcctt ttttaggttg aaccaacatt tgtacatctg gcattttttg
    49681 gattatttct ttcaaaatta aaatatcttt gctaattgtt ttcgtagata catataattg
    49741 ttctgataat tctttgtaag ttgtgtgctc attttcaatc aaaaagtata gtattttcat
    49801 ttgccgttcg ctaaattcga tgcccattat cttcacctcc tgaatacagc ttaagtgtac
    49861 aattattatc tctattttca tacagaagaa agttcttgat taatgtagaa gtttctaata
    49921 ttcttgatta tttcaaatca ataaaaaagc ctgcaatatt tatatcacag gcttttttct
    49981 ctattaaata tatataagat aatacatttt tctactagtt ctcactaatc ttgtataatt
    50041 aaaccctccg caacttgacg gagatggaga agatgccccc gtctaatcta gcggtcatct
    50101 ctcctcccat tccttccacc aatttttttg acaggtaaag cccgattccg ctagattccg
    50161 tatttgtgcg gctggtattt tcggtataaa aacgctggaa gactttttca acagaggttt
    50221 gcgttcctgg tttgatagga ttggccactg ttaatcgaat gaatggatcc tcttttgaaa
    50281 atgtcacctt tgcttgtcca tctgcataac gcaataaatt ctgtatgata ttttgcagca
    50341 ctcgcagcaa catgagcgga tctgctaata cagttgtatt tatcgagtgt tcagcgaacg
    50401 ctacctcgat atttttctca gaaaattgtt cataaaaaga gaaaaatact tcttccacct
    50461 ctttagaaaa agaaagcgta tggagatcca tttctttttg cttcgtctct attcgagcaa
    50521 gatcataaaa ctgatccgtc atactgagta atcttgcaac agattgtttg atgatcgtta
    50581 aatacttctc ccgtttctcc gtatcctcta cctgttccag taattgtaca taaccgttaa
    50641 tagcagtcaa aggagttctg agatcatgag aaaggccgac gatcgatagt ctgatgtttt
    50701 cttccatttc ttgaaatgct tgtccttttt gttcattttc atccaaccat gtattcagtg
    50761 catctactag gtccattaga ttcttttctc gaaattcgac tgaaagacga ccaccatatt
    50821 cttgtcgttc agaaagagtg gcgattttct tagttaatct cttgatttcc ctttgcagga
    50881 agaaaataaa acttcccata aagataacaa cgagaagcaa cagccattta atcaaatcta
    50941 aaccccactc cccacaccgt atgaatatac acagcatgtg cctttgctag cttccctcga
    51001 agattggaaa tatgcatatt cactgttttc tcactatcaa aatatggttc ttgccaaact
    51061 gtttcataaa gatttgctcg cgaaaatact tttttcggat gttctaaaaa aagcttcagc
    51121 agatcgaatt ctcttcctgt caaatggaca gccacaccat tcacatttac atccctcgac
    51181 tctttgtcca gtaagatttc cttgtaatag atgcgttgcg acagatcttt tacttggaca
    51241 gaagtctgat gacgaagttg gatgccgatt cgtaacaaaa gttcttcgat atcaaatggt
    51301 ttcgtcacat agtcatccgc tcctgctgcc aacaaggaaa ctttatctct ttgatcgctt
    51361 tttgctgaaa gaacgatgat cggaacattc gatgtctgtc ggatttctgc taacaatgct
    51421 tcacctgaaa gccctggaag catgagatct agaaggatca aatcgacagg atatgtgctt
    51481 aacaataatt ttccttccgt acctgaataa gcatcaagaa gtttgtatct ctgttcaaga
    51541 acctcctcca gtaaggaatg aacagcttca tcgtcttcga taatcaaaat agtttccagc
    51601 aggaccacct acttaatgtc agatttttgg aaaataaaca ttcctagagc tgatgatacc
    51661 acgattgtta ctagactgac cagaatcatt ttcggtgctt gcgaataagt tgcttgttgc
    51721 gcaaagtccg tatacatgag ccacgtttcc gtaaaccact ccgttagaaa ttccaagcct
    51781 ttgatttttg cgaaaacacc gggaatgaag gccgttccca tgatataaag aaaagaaaga
    51841 agcaaactga cactggtact tctagtgatg aatgtcaaag ccactggaac agataatgtc
    51901 cctaatgtca gcagaagcaa tacaggaaat acttttagaa cataatttcc atagtttttg
    51961 attccctcaa cttcaccaaa tccgaaagca agtgtgtaag caagcatggc tagtcccgtg
    52021 atcaaaacca cgccaagtgt tgtgatcaaa agcgtaacga gaagtttcga cacataataa
    52081 gtcattcgat tccgtcctaa agataacgta ttgcgaatcg taccgttttg aaattcttcc
    52141 ccaatataaa agcacgcaaa tgctgcgaaa gccagaagaa tccatgcagc cattttttct
    52201 accattaaaa tccctgttgc accgttgatg actgtatccg ttgcttggtt taattcattg
    52261 ccgtattttg tatgcatata ccattcgttc caagaataaa aaagcggaag tacgaccatc
    52321 agtcctagtg agacccacat tttacggctc ttccatactt ttattttttc agcagttaat
    52381 agattaaaca tgtggattgc ctccagttaa ttgtaagaaa taatcttcca gtttttgccc
    52441 aactaggtga ataccatcca caggaacttt tgcttctacc aatgcttgat tgatggctgc
    52501 tacttggtca attccttcaa aaagctggat aacacggcta gattgtacaa aataatccct
    52561 ataaccaaga gagtcgagaa ccgttactgc ttgttccgtc gccgaagtgt caatttttat
    52621 aaattgacga gattcttgtg ccaattcttc tttcgataat tctttgatca agtgtccttc
    52681 atgcaaaata ccatagtgag tggcgatctg tgacaattca tctagcaagt ggctagaaag
    52741 caagacggtg atgccccgtt cttttaccaa acgttggatg atttctcgca tttctgccat
    52801 ccctgctgga tccatcccat tcgtcggttc atccaaaatc aaaaattctg gattcgtgat
    52861 cagtgcattt gcaatagcta aacgctggcg catacctaaa gagaaattct ttgctttctt
    52921 tttccctgta ttttccaatc gcatcatttt cagcaggtct tcgatttctc tatccgacac
    52981 accgccgttc gctgcttgga tacgtaggtt atctcttgca gttaattctg gataaagagc
    53041 aggggtttca atcgattgac ccatacgtcg tcttgctgcc tgcaaatccg tcgttccaaa
    53101 taattcgatc gaaccttcat caatcgagat caaacccata atagttctca taaaggtaga
    53161 cttacccgct ccattttccc caatcaatcc atagatcatt ccacgtttga tttcgattga
    53221 tactttatct aatgctttgg cagcaccgta ttttttggtt ataccagttg ctttcaagac
    53281 cgtttcattt ccaaaatcca tacttatcct tctttcttat tgatgagtga agtatagttg
    53341 acgggtataa agaaagcagc cagaaatgta taaagaaagt gtaaattttc caattgaatg
    53401 tcaaaaaaaa caatcggaca atacgtgtct ttcctattat caggcagttt gttatacgct
    53461 tgtatcagtt tcctgattct ttcttttcga ccaaagtcgt ttctctgtat tcctcttcac
    53521 tgaaaatttt tgcttctttc agatcaagct tgagtaattt taccagaccg gttataagga
    53581 taactatagc aagactccct cccagaaaaa ttagactgtc tcgcagacgt ggttgcgttg
    53641 tcttccaatc aaagagcgca ccaaacagtg ctaatccaag tggactggcc accatggtaa
    53701 tcgttgttat cgttgacata agtcgtcctt gtatatgcgt tggaacttct cgctgaagcc
    53761 agaccatata aaaagcaaaa gaaaacatta atccttaaaa acggacttat gaaaaataat
    53821 acatgccgtt tgggatttac aattagctac caaataagag gttatgacaa aagacttttc
    53881 acaatccctt cttccgaata aacggtgttc tcctgccaac tcctcggtca caagtcacaa
    53941 tatttatcaa acatgagaag caatttttgt aaattccttc ttatttcttg aagctgacca
    54001 cttctgtcac aacctcagaa gcggataaat aatattgttt gatgatactt tatctttttc
    54061 ccgtttgttt atagatcgaa tgatattata gaccaagaat cctacctatt aacatagcta
    54121 aaaacacaaa aaaggcactt tccaaattgt ggaaagtgcc agaaaagtta ggattaaggt
    54181 aactgcgctc agcattgctt cgcccagtac gattctcgta actcgtgaac tcgaacgata
    54241 atcgcaatta acgttttgag aactgtgaag ctttacgggc tttcttaaga cctggttttt
    54301 tcttcgtatc attgaataag tttgaaaaac cttgatttat aaaggttttc ccgtaaatat
    54361 attttattat atttgattaa atttgaaatg tttgtgttct aaaatgtgtt ctaatttaaa
    54421 ggcagtatat ttcgtatttt agattaaatt tttaggctca ttcattctca aatccattct
    54481 attcagtcaa taaaaatttt aaaaagactt tataaacaaa gatgttcaag cgagcatctt
    54541 atttttttgt gcttaatttg aaaggagaac atttcatgta taaaaaacaa aaaaagaaat
    54601 tatgtgtatt aactattttg agtttggctg ttcaagcaat tgttggagca attgctccta
    54661 cgattacttt tgctgatgaa attacccatc cacaaacggt aaccgtagaa ctagatttag
    54721 cacatcaata tgctgttgaa ggaactttta gtgatggtcg tccaatgtca gaagtcactg
    54781 ttccgcatta tgcagtgtac aacggcttta aacaagatat tttctgtatt gaaccaggag
    54841 tcccgattta caatgagttc actcctggct atgagaaaaa cccgttacca gatatgtccg
    54901 ataaagccaa attagtttcc gttttatgga aaaaagtagg tacagatgca gatactcata
    54961 ttgtggcaca gaagatgatc tggcaagaag ttaatgggta tacccttcac tcaataaaac
    55021 gatcagatgg tagtgccgta aatatcgcag ccattgaggc aaaaataaat caagccattg
    55081 acgattatca gaagaaacca accttccata atagtacggc taaaacagta ttagggcaat
    55141 cgactactgt gacggatacg aataatctga atttgtcaga gttcgatgag gttgtggaaa
    55201 atgccgcaaa cattgattat cgtgtgaatg gtaatcagtt gataatcacc ccaaatgcca
    55261 attcaaaaga aagtggtgtg ctgacgctta agaaatctgc tggtaccgga acacctgtcg
    55321 cctataaaaa ggctggccaa cagactttaa tggccggggc gattgataaa cctaatacct
    55381 acacaatcaa aattgatgtg gaaacggagg gttctttaaa gatcaaaaaa gtcgataaag
    55441 aatcgggtga tgttgtacca ggaacggttt tccatttaga ctttggaaaa actttacctg
    55501 caaaagacgt gactactgac aaagaaggca ttgctacatt ggatgagatt cctcatggta
    55561 caaaagtaac cattaccgaa aaatcagtac cggcgcctta tacgattgat accaccccca
    55621 tgactaccac cattaaagca ggcgaaacca tttacgtgac ttcaaaaaac gcacgggaaa
    55681 aagggcaaat cattctggat aaaagcggag ttgaaacagg gagtgatctt tggaatgaca
    55741 attattcctt agctggtaat acgtttgcca ttcgcaaaga cagtccaacc ggtgaaatcg
    55801 ttcaagaaat gaccacggat gaaaacggtc atgcggaaac accaaaagag attgctaatg
    55861 cgttggaatt gggaacctat tatgtgaccg aaactaaagc tagtcatggg ttcgtgaata
    55921 cgttcaaacc tgtaaaagtc gaattgaagt atgccaatca aaccgtagcc cctgttacca
    55981 gtaacgtaaa agggcaaaat caagaagtca ctggcgaaac cactttgacg aaagaagaca
    56041 aagatactgg ggataaagca caaggtaagg cagtctttga gggtgctgaa tacaccttgt
    56101 ttactgctaa ggatggaaaa gctgttaaat ggagtgaggc ttttaaacca gagttagcga
    56161 agggaacgaa aggttctgat gaaacggtca ctttgacttt agacgaaaag aaccaagttg
    56221 ccgttaaaca tttagctatc aacgagtatt attggcaaga aacaaaagcg cccgaaggat
    56281 atagccttga tgaaacaaag tatcctgtat ccatcaaaaa ggtggatgat agcgaaaaaa
    56341 atgccgtgat tacccgaaat gttacggcaa aagaacaagt gattcgcttt ggctttgatt
    56401 tctttaaatt tgctggatca gctgcgggca ctaccgaaac tggcttcaat gatctgacct
    56461 ttaaagtgtc gccattggaa gggaccaatg aaatcacagg tgccgaagat gaagcgacca
    56521 cagcttataa cgagcaatta gggtttgatg gttatggcaa gtttgaaaat cttccttatg
    56581 gggattattt acttgaagaa gtagaagccc cagaaggttt tcaaaagatt acgccattag
    56641 aaatccgttc tacttttaag gaaaacaaag aagactttgt gaagagtgag tatgtcttta
    56701 ccattaccga acaagaccaa aaacaaccaa ttaaaacggt gaccgttcct tacgagaagc
    56761 tgacgaacaa agcattttct gttagtttga accgtttaat gctctatgat ttgcctgagg
    56821 aagaagatag tttaacttct cttgcgactt ggaaagacgg aaacaaagaa ttaacttctc
    56881 tggattctac cgagctagtt gataaattga gttacaatct acatgaaatc aaagaagact
    56941 ggtatgtggt agcgcaagcc attgatgtgg atgcgacaaa agctgcccaa gaaaaagatg
    57001 aaaaagccaa accagtggtg attgcagaaa caagcgcaac gttggcgaac aaagagaaaa
    57061 caggaacttg gaaaattcag cataaattaa ccgccgaaca agttttaaat aaaactattg
    57121 tcttattcaa ctatgtgtat gaaaataagg aagcttttga agcaggcgat aagccagtag
    57181 cgaaggatgt tagcttgaat aaccaagccc aaactgtcag ttgtacagtg gaacaccatg
    57241 tttctatcca aacaaaggcc cacctagaaa acggttctca gacctttact catggtgatg
    57301 tggtggatat gtttgatgat gtgtcgatta ctcatgatgt actggatggc tcaaaagaag
    57361 ctttcgaaac aattctgtat gctttattac cggatggtac aaacaaagaa atttggaaat
    57421 ctggcaagat tgattatgaa gtaaatgata aagaattcac caaaactgtg cttgcgaaaa
    57481 aagtagatac cggaaaatat ccagaaggaa ccaagtttac ttttgcggaa atcaattacg
    57541 ataaagatgg gaatatcaat ggaaaacaca atgaagattt gaaagaaaaa tctcaaacct
    57601 taacaccaaa agaagttcca accatactaa gtacgccgaa acaaccggaa acaccaactg
    57661 ttccaagtgg ctctcaagaa tctagtccca cagtgaagac cttccctcaa accggggaga
    57721 aaaattccaa tgttttactg ttcattggtt ttactttgat ttttgcgacg gcgggctatt
    57781 atttctggaa tcgccggaac taaggtgatg agatgataca agtaaatcct aagaaccaac
    57841 gtgcgcgacc gcctcctaaa aaagtagtcg cgctattttt gtatccaaaa ctaacaatga
    57901 aaagaggaaa agaagatgga attgaaattt gtcgtgccag atatggctga aacctttgga
    57961 aagttaagtt atgccggtga aggagaaatt ataacagaag gatatggacg gaatactacg
    58021 gtgattggtc gcagttatca tttgtattcc agtaagcaac gggccgatga tattgaggtg
    58081 gtagtagctg cggaagccgg tgaaaaggat tttgatcaag accaaccgct aaaagccgtg
    58141 aatccccatt tggttgccaa aggctatgag attgagaatc gtgggtttac tgattacgtg
    58201 ttgtatgttg atgatttagt gaaagcatag gaggaaaaga agatgagatt aacagaaggt
    58261 attgtcgtag attcaggttt aacatttggg aagttgcgtt tttccgcatt acgccgagaa
    58321 gtacggaagc aaaatgagga tggaacaatt ggtaatgagg taaaagaacg aacctataat
    58381 ttaaaatcct ctgcacaagg gcgaatgatt caagttagta tcccagctaa tgtaccctta
    58441 cgcgagtttg cttatgatgc agaggtagag ttggtcaatc caatcgtgga taccgttgcc
    58501 aattatgttt ttcgagaagg aactaccgtt aattggttca ttaaggcgga tgatttagtc
    58561 ttgaagcggc agccgaatca aggaaatcct acgaaccaaa atgaaagaaa gaaataggtg
    58621 aagattatgg aaattaatgt tgaacatatt ttagattgtc tcgatcaata tggaaaaggc
    58681 gagctgactg aggaacaact cgttaaagca ttaacctctg atgaaaaaat gtttctgatt
    58741 atacatcaag gtttacttgg agaaaatagc gacagtgaag aagactctga tgtactagac
    58801 tggttaggag aagaagagtc tttctttata gttgtcgaag taaatgaaaa cttatgtcgg
    58861 caggcagaat ccattttgga agaaattggt gtggagatgc cggatgctat tgaaggcttt
    58921 ttaaatcaat tggttgaaac gaaacaactc ccctcctcgt agcagtaaat gactagcata
    58981 actttttgaa attgcctaat gaaatcctat tgggcttttt cgattggagg tggaaaccat
    59041 caaaatgtac aaaggacatc gcatacgcgc aggagatcag cacttggttt atcactttgt
    59101 tcttggctgg ctactcgctc tgttcatcgg ttggatgagc gtcttttatt ttcaagagtt
    59161 tagacaattt gatatttcta agctatcact ttctactatt gaaatcgttt ggtctataaa
    59221 agatttagta tgtctgcttg gaagtctcgc tttttcagga gctatgatat tgctttatat
    59281 tcactttttt cttgatcatt ggcgaagctt gtggcatcga caaaagctag ctcggatgat
    59341 tctagagaac cattggtatg aagtgaaaca aactcaaagt gaaggctttt tcaaagattt
    59401 gaatagtagc cgaaccagag agactatcag ttacttcccc aaaatctgtt atcgaatgaa
    59461 agatggatta ctgtctattc gcgttcaaat ttcacttggg aaataccaag atcagctttt
    59521 aaaattggaa aagaagttag aaagcggact gtattgtgag ttagtagaaa aggaactcaa
    59581 agactcctat gtggagtata ctttactgta tgatatgatc gccaatcgaa ttgggataga
    59641 cgaagtagtg gcagaaaatg ggactctgcg attgatgaaa aatcaagtat gggcttatga
    59701 ttctttaccc catatgttaa tcgctggtgg cacgggtgga gggaagacct atttcctcct
    59761 caccattatc gaagcactat tgaagtcaga tgcagaattg tttatcctcg atcccaaaaa
    59821 tgcagattta gctgatttag gtacggtgat gcctcatgtt tattcacaaa aggaagaaat
    59881 ttctgcttgt gtggaagatt tctatgaacg tatgatggct cgtagcaagg caatgaaaga
    59941 aatgtctaac tacaaaacag gagagaatta tgcctatctt ggacttccac ccaacttttt
    60001 aatctttgat gaatacgtgg cttatatgga gatgttaacg acgaaagaaa gtgcggtgat
    60061 tttgaataag ctcaaacaaa tcgtgatgtt gggtcgtcaa tctggtttct ttctgatttt
    60121 ggcttgccaa aggccggatg cgaaatattt aggagacgga atccgcgatc aattcaactt
    60181 tcgcgtggct ttgggtcgta tgagtgaact cggatattcc atgatgtttg gggaggtcga
    60241 aaaaaacttc tttatgaagc acatcaaagg tcgaggttat gtggatacag gtggcagtgt
    60301 gattagtgag ttttatacgc cacttgtacc aaaagggtat gatttcttag attcaattag
    60361 taaattagaa aagatgaatg attgagtgat cttcaatact gactttatac ttcaagtaac
    60421 gtataatact tttatatagt aggaagaaag gggataatta atatggaaag taatgattct
    60481 tatttagagt atgcaaaagc aaataaggat aagtttattt cttatattat caaagggaaa
    60541 tcccccgaag ttggacgaga cgcagttttt atggcaggga gtcctggggc tggaaaatca
    60601 gaggttgcca ttggattagc tgagaattat gataaccatg tgattattga tgcggattac
    60661 tttcgcaccc agtttcctga ttataatgga aaaaactcta gtctctttca aaaagcatct
    60721 tcttggttgg tagagcaggc atttagatat gtcttagatc atggctattc ttttattctg
    60781 gatgcaactt ttgcaatatt aagtgctgaa aaaaatatct cgcgggcgtt gaaaaaacat
    60841 tttcgagtga cgattttcta tgtttatcaa gaccctaaaa tcgcttggaa atttacacaa
    60901 gaacgtgaaa ttgcagaggg acgtcatgtg ccgaaaaagg catttattaa cgcttttttc
    60961 aaatcaagag agaacattgc aaaagtaaag agtaaacatc cagatgtatt gcttcatatc
    61021 ataataaaag attatacgaa taatatttcc gaagttcatt atgctacgga taatctagaa
    61081 ttatttttac cactagggta tagtaggaaa gatttggagg ttcaattaca tgactgagaa
    61141 agaacaagta acgaaaattg taaagaaata caataagagc attgcggatt tatcggaaaa
    61201 tgctactgca aaagagttca aaacggtgat taaatatgta gccgatcagg ccaatgaaaa
    61261 acaacggaaa ttagttggat taaataaaaa atagtaggac aaattaataa tgtatgagcc
    61321 aagagcaaaa tgttcttggc ttttttcttt gcaatgaatg aggtaatgta tgagattttt
    61381 agatttattc gccggtattg gtggctttcg tttaggtatg gaacaggcga gccatcattg
    61441 tatcggtttt tgtgaaattg ataaatttgc tagacgtagt tataaagcaa ttcatgatac
    61501 aagtaaggag gtggaaatgc atgacatcac aagtgtatca gatgagttta ttcaatccct
    61561 cggaccagtg gacatccttt gcggcggatt tccgtgccaa gctttttcaa ttgcgggaaa
    61621 gcggcaaaga ttttccgata ctcgaggtac tttattcttt gaaatcgctc ggttcaccac
    61681 tcttctccga cctaagcttt tattccttga gaacgtccga ggattgctca atcacgaagg
    61741 aggggctacg ttcgagacga tcctccgaac gctggatgga ttggggtatg acgtggagtg
    61801 gtaggtgctt aactcaaagg cctacattcc ccaaagccgg gagcggatat tccttatcgg
    61861 acattctcga gacgcatgta ccgaacaagt atttcctatc attggaccgt cttcaacatc
    61921 tgatcaaaac atcagaaatt tggtaaatat caatccttcc aatcgaggaa tgggtggaca
    61981 agtctatggt tcagatggcg tagcgccaac cttaacaggt gatgaaggaa tcaaaatcgc
    62041 actgccagca agggatggaa tctctgtagc aggactatta ccgggaaagt ttgaacaagg
    62101 taatcgagtt tatgaagtta ctggaaccgc ccccaccttg tcaacgaaac aaggtggtac
    62161 aaaaatcatg attcgaaaaa atgaaacaga atatcaagag gtgaagccag aagacagtgt
    62221 gaatctggct tttcctaatt ccacaagtcg ccgaggtcgt ctgggaaaac agagtgttca
    62281 taccttacta acaggagacc aacaagcgat cgtcacggat cagtatcaaa ttcggaagct
    62341 aacacctaga gagtgttggc gacttcaggg ctttcccgat tgggcttttg atcgagattc
    62401 tcaagtcaat tcagatagtc agttgtataa gcaagccgga aactctgtaa cagttccggt
    62461 catttttgat attgccagaa gattaaaaga gttggatgta catggtttat gatgagttga
    62521 ttggagaaat ttattgggtg attggaaaga ttcagtcaga cccagaatta gaagaacaat
    62581 tgcgacggtt aaaatttgat attcgcaaga atggtgtcaa agtcgctggc gatccatatt
    62641 taatgaatga ggagacggat gctcgaattg aaataaatca agtaattgca gaatttgagc
    62701 ggattgcgga ccaagcaaaa gaaccagata ttcgtcaata cttgttagaa atgaaagcag
    62761 agttggaagt aaatggtatt acagatgagt aacctaaacc aacacaactg actgttaggc
    62821 gctgaccgcg gaggattcgc gaagcagaaa tcctccgtgg tgctgtgcct gttcatggac
    62881 ggcgttagcc gaccatgatg tctcaccccc gtatctaaca ggggggtaca aaaacacaaa
    62941 aaataagtaa gcaaccatta agaatgcttg ttgtatcaaa gatagtaagt aatttgtata
    63001 ggtgttaact catttgaaaa agttaacacc ttgaatttgg aggtgagaac ttggcacaac
    63061 ggaatttaga ttatcggcta ttaaaagacc gacgcaacga atacggcgtt tcacaaaata
    63121 aattggctac ggcttgtgga cttagtcggc cgtacttaaa tcagatagaa aatggtggcg
    63181 taaccgcatc tataaaaacc atgaggaaaa tttttgacca actggaaagc tttaatcccg
    63241 atttgccttt gacgttactg tttgactatg taaggattcg ctttcccaca acggatgcac
    63301 gaaaaattat tcaagaaatt ctccatttga aatttgagta tatgctccat gaagattatg
    63361 ccttttactc ctatcaagaa cagtatgtca tgggtgatat tgtggtgatg ttgtctcatg
    63421 aagaagataa aggtgtgctt ttagaattaa aggggcgagg ttgccgacaa tttgaaactt
    63481 ttttactcgc tcaaaagcgt agctggtacg actttttcga ggattgtcta aaggccggtg
    63541 gcgtgatgaa acgcttggac ttggcaatca atgatcgagt ggggctattg gatatacctg
    63601 agctaacgaa aaaatgtcag aaggaagaat gtatctcctt gtttcgtacc tttaaaagtt
    63661 atcgttccgg ggaactttta aaggctgatg aaaaggacgg catgggcaat accttatata
    63721 tcggcagtct caagagtgag gtttatttct gtttgtatga aaaagactat gaacaatata
    63781 tcaagttagg gattccatta gaccaaactg agacgaaaaa tcgttttgag attcgactga
    63841 aaaatgaccg tgcttttcat gcgattcaag atttgttaaa aggtcgtagc attgagagca
    63901 ccacgttttc cattatcaat cgttacttgc gatttgcgga taaagtagaa ggtaaaaggc
    63961 gaaccaactg gcccttgaat gaacaatggg ggcgttttat tggacggaat cggaaagaga
    64021 ttcaattaac ttccgagcca aaaccgtata ccattgaacg aaccttgaat tggctaggcc
    64081 gacaagtcgc ccctacgtgg aaaatggcta aggagttgga tcgattgaat cggacaacct
    64141 atatccagga tatggtacag aatgcacgct tatcagaccg acataaaaag attttggagc
    64201 aacaaagtat ggcaattgaa aatttgatta tatgaaaaga ggaatcgtca tgggaattgt
    64261 aaaagatatt tttttggtat ttggtggcag tatgcttggt gttactgtga tgtgcttgat
    64321 gaatgcaagt gcagcagcgg atcgagcaat ggaaaagaaa ggaaagtgac aagatgaatt
    64381 tcggacaaaa ttt
//
LOCUS       DAFLWZ010000006        62316 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000006 DAFLWZ010000000
VERSION     DAFLWZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.006"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..616
                     /locus_tag="L1V38_000402"
     CDS             <1..616
                     /locus_tag="L1V38_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1314980.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="L1V38_000403"
     CDS             613..1386
                     /locus_tag="L1V38_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1314981.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="L1V38_000404"
     CDS             1383..1781
                     /locus_tag="L1V38_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBN1314982.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="L1V38_000405"
     CDS             1966..2637
                     /locus_tag="L1V38_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314983.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="L1V38_000406"
     CDS             2696..3136
                     /locus_tag="L1V38_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1314984.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="L1V38_000407"
     CDS             3148..3816
                     /locus_tag="L1V38_000407"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1314985.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="L1V38_000408"
     CDS             3880..4503
                     /locus_tag="L1V38_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1314986.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="L1V38_000409"
     CDS             4559..4945
                     /locus_tag="L1V38_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBN1314987.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="L1V38_000410"
     CDS             5158..6549
                     /locus_tag="L1V38_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBN1314988.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="L1V38_000411"
     CDS             7160..7528
                     /locus_tag="L1V38_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBN1314989.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="L1V38_000412"
     CDS             7708..8649
                     /locus_tag="L1V38_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBN1314990.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="L1V38_000413"
     CDS             8718..9449
                     /locus_tag="L1V38_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBN1314991.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="L1V38_000414"
     CDS             9593..11773
                     /locus_tag="L1V38_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBN1314992.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="L1V38_000415"
     CDS             11793..12275
                     /locus_tag="L1V38_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBN1314993.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="L1V38_000416"
     CDS             12291..13052
                     /locus_tag="L1V38_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1314994.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="L1V38_000417"
     CDS             13183..14517
                     /locus_tag="L1V38_000417"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBN1314995.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="L1V38_000418"
     CDS             14824..15309
                     /locus_tag="L1V38_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBN1314996.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="L1V38_000419"
     CDS             15302..15985
                     /locus_tag="L1V38_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBN1314997.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="L1V38_000420"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="L1V38_000420"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBN1314998.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="L1V38_000421"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="L1V38_000421"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBN1314999.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="L1V38_000422"
     CDS             19601..20230
                     /locus_tag="L1V38_000422"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBN1315000.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="L1V38_000423"
     CDS             20282..20614
                     /locus_tag="L1V38_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1315001.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="L1V38_000424"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="L1V38_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBN1315002.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="L1V38_000425"
     CDS             21440..22813
                     /locus_tag="L1V38_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1315003.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="L1V38_000426"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="L1V38_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBN1315004.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="L1V38_000427"
     CDS             23868..24308
                     /locus_tag="L1V38_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1315005.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="L1V38_000428"
     CDS             24452..25153
                     /locus_tag="L1V38_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBN1315006.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="L1V38_000429"
     CDS             25150..26271
                     /locus_tag="L1V38_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBN1315007.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="L1V38_000430"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="L1V38_000430"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBN1315008.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="L1V38_000431"
     CDS             27650..28558
                     /locus_tag="L1V38_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBN1315009.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="L1V38_000432"
     CDS             28593..28865
                     /locus_tag="L1V38_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBN1315010.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="L1V38_000433"
     CDS             28876..29922
                     /locus_tag="L1V38_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBN1315011.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30173..32782
                     /gene="clpB"
                     /locus_tag="L1V38_000434"
     CDS             30173..32782
                     /gene="clpB"
                     /locus_tag="L1V38_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBN1315012.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32933..33619)
                     /locus_tag="L1V38_000435"
     CDS             complement(32933..33619)
                     /locus_tag="L1V38_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315013.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33597..34091)
                     /locus_tag="L1V38_000436"
     CDS             complement(33597..34091)
                     /locus_tag="L1V38_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1315014.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34111..35331)
                     /locus_tag="L1V38_000437"
     CDS             complement(34111..35331)
                     /locus_tag="L1V38_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315015.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35478..37313
                     /gene="lepA"
                     /locus_tag="L1V38_000438"
     CDS             35478..37313
                     /gene="lepA"
                     /locus_tag="L1V38_000438"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBN1315016.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            37509..38420
                     /locus_tag="L1V38_000439"
     CDS             37509..38420
                     /locus_tag="L1V38_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315017.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            39416..39667
                     /locus_tag="L1V38_000440"
     CDS             39416..39667
                     /locus_tag="L1V38_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315018.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            39750..40022
                     /locus_tag="L1V38_000441"
     CDS             39750..40022
                     /locus_tag="L1V38_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315019.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            40112..40351
                     /locus_tag="L1V38_000442"
     CDS             40112..40351
                     /locus_tag="L1V38_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315020.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            40498..44781
                     /locus_tag="L1V38_000443"
     CDS             40498..44781
                     /locus_tag="L1V38_000443"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBN1315021.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            44880..45245
                     /locus_tag="L1V38_000444"
     CDS             44880..45245
                     /locus_tag="L1V38_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315022.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            45247..45699
                     /locus_tag="L1V38_000445"
     CDS             45247..45699
                     /locus_tag="L1V38_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315023.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            46313..47623
                     /locus_tag="L1V38_000446"
     CDS             46313..47623
                     /locus_tag="L1V38_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1315024.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            47646..47957
                     /locus_tag="L1V38_000447"
     CDS             47646..47957
                     /locus_tag="L1V38_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315025.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            48317..49573
                     /locus_tag="L1V38_000448"
     CDS             48317..49573
                     /locus_tag="L1V38_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1315026.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            49570..50115
                     /locus_tag="L1V38_000449"
     CDS             49570..50115
                     /locus_tag="L1V38_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315027.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            50116..50616
                     /locus_tag="L1V38_000450"
     CDS             50116..50616
                     /locus_tag="L1V38_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315028.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            50697..51253
                     /locus_tag="L1V38_000451"
                     /pseudo
     CDS             50697..51253
                     /locus_tag="L1V38_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            51273..51617
                     /locus_tag="L1V38_000452"
     CDS             51273..51617
                     /locus_tag="L1V38_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315029.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            51636..52547
                     /locus_tag="L1V38_000453"
     CDS             51636..52547
                     /locus_tag="L1V38_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1315030.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            52626..53618
                     /locus_tag="L1V38_000454"
     CDS             52626..53618
                     /locus_tag="L1V38_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1315031.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            53615..53833
                     /locus_tag="L1V38_000455"
     CDS             53615..53833
                     /locus_tag="L1V38_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315032.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            53846..54256
                     /locus_tag="L1V38_000456"
     CDS             53846..54256
                     /locus_tag="L1V38_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315033.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            54308..56836
                     /locus_tag="L1V38_000457"
     CDS             54308..56836
                     /locus_tag="L1V38_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1315034.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            56852..59062
                     /locus_tag="L1V38_000458"
     CDS             56852..59062
                     /locus_tag="L1V38_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315035.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            59070..60161
                     /locus_tag="L1V38_000459"
     CDS             59070..60161
                     /locus_tag="L1V38_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1315036.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            60182..60724
                     /locus_tag="L1V38_000460"
     CDS             60182..60724
                     /locus_tag="L1V38_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315037.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            60919..61176
                     /locus_tag="L1V38_000461"
     CDS             60919..61176
                     /locus_tag="L1V38_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315038.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            61190..61522
                     /locus_tag="L1V38_000462"
     CDS             61190..61522
                     /locus_tag="L1V38_000462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315039.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            61567..62115
                     /locus_tag="L1V38_000463"
     CDS             61567..62115
                     /locus_tag="L1V38_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1315040.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            62122..>62316
                     /locus_tag="L1V38_000464"
     CDS             62122..>62316
                     /locus_tag="L1V38_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315041.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELV"
BASE COUNT        21022 a        10147 c        13458 g        17689 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
    30001 tttttttata tacatacaat caattttgtt tttttaagat ttatataagt cgagaaaaaa
    30061 agtcaaaaaa ctatgtgtat attttgacca aaattgacca aagcgatata atagtttttg
    30121 taaagatcaa agaaataagt gatcttacct ttaattagga gggtatacct gtatgaatat
    30181 tgagaaaatg actacgacgc ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac
    30241 tcgaaaacat caagatatcg acattgccca tgtatggaaa atctttttac aatctaatca
    30301 ttttggtcga aatttctata cggatgccgg attggatgtc gaatcttttg aacatgaaat
    30361 tgatcgtcta ctggatgagt atccagttgt ttctggtgga aacgtccaat atggacaaaa
    30421 cctcagccag aatttctttc gattattgaa tgaagcagac caaatacgtg aaagcttcgg
    30481 cgacgagttt ctttcaacgg aagtcgttat tttagcgttg atgaaattaa aaaattatcc
    30541 gttaactgtt tatttgaata aaaacggatt atctgaaaaa gaattgcgta aaaacatcga
    30601 agagatgaga ggaggagaaa gagtgacctc acaaaaccaa gaagaacaat acaaagcatt
    30661 agaaaaatac ggcgttgatt tagtacagca agtcaaaagc ggaaaaatgg atccaatcat
    30721 cggtcgtgat gaagaaatcc gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa
    30781 tcctgttctg ataggagaac ccggtgtagg gaaaacggca atcgttgaag ggcttgctca
    30841 acgtatcgta cgcaaagatg tgcctgaaaa tttaaaagat aaaacgattt tttcattaga
    30901 tatgggtgca ttgatcgctg gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc
    30961 agtcttgaaa gaagtcaaaa aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca
    31021 caatatcgta ggggcaggaa aaacagaagg aagtatggat gccggaaatc tgttgaaacc
    31081 aatgcttgct cgcggtgaat tacatttgat cggtgccaca actttagatg agtaccgtca
    31141 atatatggaa aaagacaaag cgttggaacg tcgctttcaa aaggtattag tcaaagaacc
    31201 aacagtggaa gatacgatca gtattctgcg tggattaaaa gaacgttttg agatccacca
    31261 tggtgttaac atccatgaca acgcattagt agcagcagct actttatctg accgttatat
    31321 tactgatcgg ttcttaccgg acaaagcaat cgatttgatc gatgaagcca gtgcaacgat
    31381 tcgggtagaa atgaactcta tgccaacgga attagatcaa gttactagac gtttgatgca
    31441 gttggaaatc gaagaagctg cactgaaaaa agaatcagat gatgcaagta aaaaacgctt
    31501 gaaaaatttg caagaagaat tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca
    31561 gtgggaaaca gaaaaagaag aagtcaattc tgtttcagca aaacgtgctg aaatcgataa
    31621 agcaaaacac gaattagaag atgcagaaaa taactatgat ttagaacgcg ctgctgtatt
    31681 gcgtcatggt acgatacctc aattagaaaa agaattgaag gaattagaag ctaaagcaaa
    31741 agacagcgag attaagatgg ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt
    31801 tggcagatta acgggtatcc ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat
    31861 taaattgaat gaaacacttc ataaacgagt gattggtcaa gatgaagcag ttgatgcggt
    31921 cagtgacgcg gtaattcgtt cacgggctgg attgcaagac ccaaatcgtc ctctaggttc
    31981 tttccttttc ctaggaccaa ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga
    32041 gaacttgttt gactcagaag atcatatggt acggatcgat atgagtgaat atatggaaaa
    32101 acatgctgtg tctcgtctag tcggagctcc tccaggctat gtaggttacg aagaaggtgg
    32161 tcaattaacg gaagctgtca gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga
    32221 aaaagcgcat cccgatgtct tcaatatctt gttacaagtc ctagatgacg gacgcttgac
    32281 tgattcaaaa gggcgagtag tagatttcaa aaatacggtt ctgatcatga ccagcaatat
    32341 cggttcacag ttactgctgg aaggcgtgac tgctgatgga acgattccag aagcagtggc
    32401 tgaacaagtc aacacgctat tacgtggaaa cttcaaacca gaattcttga accgaatcga
    32461 cgacacgatt ttatttacac cattgagcct agacaacgtg aaaggaatcg ttgacaaaat
    32521 ggtggcgcaa ttggcacaac gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga
    32581 agccaaaacg tggattgctg aaaatgctta tgaaccagca tatggtgcaa gaccattgaa
    32641 acgatttatc actaaggaag tagaaacacc actagctaaa gaaatcgttg caggacatgt
    32701 tatgcctaaa tcaaaagtaa cgattacttt acttgatgga caacttcatt tcaaaacaga
    32761 agagctagaa gaaatcgtct aatcttccat tgagactata aaagaaaaaa ggggtctgac
    32821 acaactagtg tcagacctcc ttttttcaaa taaacagtgt tccagaagta gtttcttcga
    32881 aaaataagcc gaaatttctt gaagctgccc gcttctgtca caacctcttt tattaggtat
    32941 ttttcacttt ttctaattta taactttcaa agtaacgctc atctttttta ctttgagacc
    33001 atgcaaacaa tcccattaag gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat
    33061 ccatcaatgc tgctcgtccg acaaacagtg tgccatcaga agcagcaaaa cgttgaagat
    33121 tcatgcctaa gaactggtcg cataagaatt cccagaactc ccaaaacacg ccgcaaagtc
    33181 cagcaaacgc aaagccgaat aagaggaaca accaaggact ggtttttgat atctcagcat
    33241 ctttcatcaa gtaaccaatc aatccatagc caagagctgt caggaccatt ggactcaccg
    33301 catgtaagat tttgtcccaa aaagagatga tactgatcaa atgcatccct gtgcctaaaa
    33361 agacagagat gaacaagaaa aaccagtaaa acaaaacgat tgctgctggt attttaagtt
    33421 tgaaaacttt caaaatgact tgtggcatga aaatcaatgc aatccctaat aaagattcca
    33481 cgataaatgt gattccttga gaagtcgaat atttttgtgt gataaattca taaaaattat
    33541 agcagacaac gaatacacca aaagcaagta aagctatttg cacctttttg atttctttaa
    33601 tcactgaaag tccctccatc taaaaatctt tttacttctg aaagcaactc aatttctgaa
    33661 gaaaccactt ttccgttcaa tttgatcaaa cctattgtat ataagttcag gtagtgaaat
    33721 tgattttcag ctgtttcttg tagtgcagcg atttttttcg ggtgggttcc gccttgctgt
    33781 cgagtatcag tatataagcc gatcactggg atgcctttcg cataagccac accgatttcc
    33841 gatgctaccc cggcatcgat cgtcagccca tctagtaaag caatcattaa atcactagcc
    33901 aacacttttt ctgtgtcagc aagagcaatc attcgactgt ctgcataagc agttttgtca
    33961 ttgattgctt cattttcttg aggaagatag atcgaaagct cagaagagag ctctctgatt
    34021 tctttaacta actgttggtt atataacaaa tcacttttag caaacattgg tgcggcaaaa
    34081 taaattttca tctaaacatc atccttttta tcaaaaataa tcgctaaagt aagcttccat
    34141 gtttggaatg atacgctcta gtgacttcag tgtttcttca tctgtttcta accgttcgat
    34201 tcttgccaaa taagaagcac ggcgataatt catcatcaag caagtcaatg tttggatatc
    34261 cagtcgaacg gattttccta taggttcatt taagacacgg acttgtccct gttcatccca
    34321 tgttaaagcg aagacaccat tattccaagg agcgacagga tcttcaatga tgaaatgaaa
    34381 agcatcagct gttccaacaa acggaaaccg ttgaaggaat tcttttacat caacgatccg
    34441 agccataaaa tatggttcga tctgctcttt gatctgacta tcttcaatca aaaatgctaa
    34501 aggctcattt ttataaatat ctccatgtac ccagtagatc atggaaaaat gtgcggaaat
    34561 aaagttccat aagccatttc gagcttcttg atcaagatag aacatttctt ttacgtgaaa
    34621 tatttcttca gctacccagt agaacagaac acctcttggt tcatggttgc tatcgtagta
    34681 gacagcggct gtgcgctcat cttcattttc gaaacgccaa tactcttccc aatgaaaatc
    34741 actgcggaat aaagcaccat ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc
    34801 tggatgatca actggtaatc gctcaaccat accacttact gggatttgtt taggtagctg
    34861 tgtatctctg attttaaagg aaagtttatc agacatgatt tcccatcctt tacgccgata
    34921 gtaggggata ctgtaaggat acaaataaga gatccattgc ttattcttgc gcatattatc
    34981 caatgcaacg ataattagat cttgcatcaa tccatggtta gcatattctg gataagttcc
    35041 aactccagtc acaccaccca ttttataacg tgcaccgtga atattgactt cacaaggata
    35101 gatagcgatt tgagagatca gtttattttc gtggaaccat ccgaacactt tcgatacttc
    35161 caaaatcggt tttttggaac ggataaaagc tcgtttattc tcaaacccgc tttcctcgat
    35221 gtctgcttca gtcacttgga acacatagga aagcaattca ttgaattgat cgatatgttc
    35281 ttgagtgacc ggttttaatt caagattttc tctaaaatct ttttgatcca ttttttcatc
    35341 tccatttatt agcttgataa cagtatagca aaattctaca aaaaaaactt ctatagctga
    35401 ctaattaaaa actctttaaa ttactgcttt tcgttggtat aatggaaagt gctgattata
    35461 tgaaaagagg agacgctatg gatataaaga aaatgaaaga acgccaagag cagattcgta
    35521 atttttcgat catcgctcat atcgaccatg ggaaatctac attggccgat cgtattttag
    35581 aaatgacgca cactgtgacg tctcgcgaaa tgcaagatca gctgttagac tcgatggatt
    35641 tggaacgtga acgtggaatc acgattaaat taaatgctgt agaactcaat tacacagcga
    35701 aaaatggaga aacatatatc tttcacttga ttgacacccc agggcacgtc gacttcacct
    35761 atgaagtctc tcgaagcctt gctgcctgtg agggtgccgt tttagtggtc gatgcagcac
    35821 aaggaatcga agcacaaaca ttggccaatg tttatttagc gttagacaat gatttggaga
    35881 tcctgccagt catcaataaa atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag
    35941 aaatcgaaga cgtaatcgga atcgatgcta gtgaagctgt attagccagt gccaaatcag
    36001 ggattgggat tgaagatatt ctcgagcaga tcgtggaata tgttcctgca ccaagtggag
    36061 acttagatgc accgctaaaa gctttgatct ttgactctat ttatgatagt taccgcggtg
    36121 ttgttctaaa tgtccggatc acggacggta tggtcaaacc cggagacaaa atcaaactga
    36181 tgagtaatgg caaaacattt gatgttacag aggtcggggt cttctcgcca aaagcagttg
    36241 ctagagactt tttgatggtc ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc
    36301 aagatacacg agtaggggat acagtaacgt tagcagacaa tcctgccgct gaagctttac
    36361 caggttaccg aaaaatgaat ccgatggttt attgtggtct ttatccaatt gatacttctc
    36421 gttacaacga tttgcgggaa gctttagaaa aactgcaatt gaatgatgct gctttacaat
    36481 tcgaaccaga aacctctcaa gcattaggtt ttgggttccg ctgtggattc ctcggacttc
    36541 ttcatatgga tgtcgtccaa gaacgcttgg aacgggaatt caatctagaa ttgatcacga
    36601 ctgcaccatc cgttatttac catgttaata aaacggatgg tacgactgct acagtagata
    36661 acccggcaga ttttcctgaa cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag
    36721 cacagatcat ggtcccaaat gattttgtcg gtgcagtaat ggaactttct caacgaaaac
    36781 ggggagaatt cattacgatg gattatttag atgattaccg agtaaatgtc gtctataata
    36841 ttccgctttc tgaaattgtc tttgactttt tcgacaaatt gaaatcaagc acgaaaggct
    36901 atgcctcatt ggattatgaa atgtctggtt atcaaaaaag caagttagtg aagatggaca
    36961 tcttgctgaa tggagaaaaa gtcgatgcat taagctttat cgttcaccga gactttgcct
    37021 atgaacgtgg aaaagcaatc gttgaaaaac tgaaaaaact aatcccacgc caacaatttg
    37081 aggtgccaat ccaagcagct attggacaaa aaatcgttgc ccgttcagac atcaaagcct
    37141 tgcgtaaaaa cgtcttggct aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct
    37201 tagagaaaca aaaagaaggg aagaagcgga tgaaacaaat cggctccgtc gaagttccgc
    37261 aagaagcctt catggccgtt ctgaaaatgg atgagcaaga tagtgtgaaa taacttataa
    37321 tcaatcgaaa aacctattaa ataaaccttt ttgagtagat gcaacactga ggattatctg
    37381 tataaaagat tttaaactgt catttggtta tcacggcgat actaaaatta acaaaattgg
    37441 aatatttttc ttgaagattt ttagctgtca gtatatgatg aaagcatctc ataggaggtg
    37501 cttttttcat ggttgataat tcaagtggaa gggttcttaa atctctaaga aaagagaaaa
    37561 aactatctca aaaaaagtta gctgatttag caggtatttc acaaagtact ttagttaaat
    37621 atgaaaaagg gtcaagaaaa atccctaaag acgtagataa tactctaagc aagattctga
    37681 atatagaaac tctaataaaa gatgaggaag ataagattga gattctcatc ggtaaactaa
    37741 ttgcatacag agatatgaat aagttactta acaaagagtt agctgataat ataggaatta
    37801 gtgaagtatt actcagttat gtgttaaata gaaagagaaa tccgtcaaaa gaaatgcaaa
    37861 aaaaaatcga tatttttcta ttaagtaatg aaaaagaaat tttgaaggag attaatcgtg
    37921 atagtgagat atttagttta tcaaaagacg ataaaattgt tatgggaaaa agaatacgag
    37981 aagtccgaaa gaaccgggaa gagacgcttg aaaaatttgg taaaaacttt accatctata
    38041 caggcaaaaa tgttataagt agatgggaaa aaggtattaa tattccagat attgaaaaac
    38101 taatgaatat tgcctatctt ggtaaggtca ctgttcctta ccttatgtac ggagaagatt
    38161 ataagaatat acttccaaaa gatgaaagag ttagcgattt taaaaagata aattctttta
    38221 gtatgggatt aaggatgagg aaaattagga aagattatta tctagaaagg gaggagtttg
    38281 gaaagctttt ttctccttca atttcaaaat ggtccataga taggtatgag aatggtagag
    38341 atatacccaa tactaatcga attatccaat atgcttatat aggaaatctt tctttagaat
    38401 ttttgattta cgggatataa aaatagttta cgtcgatact tattaagtta tcgacgtttt
    38461 ttattataga aaaaatttat aaaaggaggt ttcttgatat gataagaaac aaaaagggtt
    38521 tgttgaaagt tgctttactg gcagcttttt tctaagtaac tttttgacaa gctcaatggc
    38581 aacacaagcg gaagaagtaa tacaagaact aactgttatg aataacagct agataaaatg
    38641 ggctatgtat gttatccaac aatttagtaa tcactagaag cctagcgaaa gttcgcttga
    38701 taagttatag atgagtattg atttgtagtg tttccaaatc aaaagggtac agagccacat
    38761 gaaatatgtt gtcctctgca gcgtcaggat gggaatccat accatggaga ttcggagatc
    38821 tgtgagggaa tacttacgtg gttaatatgt cagttgtgtt ggacgtagta atggtcatag
    38881 tgggtagatt gactgaattc ttatatgaga aaatgaaacc aacaagaaga tagggttatt
    38941 tatacagaat tggggatctt ttctggaaaa gtaatcggat aatgcgagat tcgtacggtc
    39001 ttttttaaat ttctctaaaa aaaacggcat cgaatgggtt gggtgattga taagcaatga
    39061 atcatagact gatatagaat aaaaaatgat tctatttatc tttttacatc tatcgttttt
    39121 tcaagtagcc gcaaattata tcagcattca acaatttttg tatacaagtt ctagtaaaag
    39181 gatctgaaga aaaagttggt tgttgtgaag ataaaaaaag aatcaggttt tactgagttt
    39241 ttcttcaaaa tttgtgttat taggttagga caaagataag aagaagtatg aagatttaaa
    39301 aaaggaatga ggaaaagata gtaatttccg attattggag tttttttatt tataaagaag
    39361 aagcgaataa gttgtgattc ctagatttcg cgcgtgatta attaatgagc aaaaaatgcg
    39421 gaaagtttta gtgtttaata cacgaggaca aagtttctta ggtattgaag gcacacgtgt
    39481 aacggttgat gggtggtgtg attgtttcga ggttggaaaa catgttgaac ttatggcatt
    39541 tactgagcta aaagataaga acaacgtgga atttttcgag agtgatattg gttgggacga
    39601 tcatgaagaa gtttatggaa aatttatttt gcggaaggga aattcttata cgaatgggga
    39661 agcataagta gcgatttgtt agagatcatt gataggattg aaattgtcgg gaatatttat
    39721 gagaatctag agttatttga ggtgatagaa tgagtgatgg ttttgaacaa gtatcaataa
    39781 ttaaaaatca agttcgggag attcttagaa aaaaaggcta tttggtagat agttattttg
    39841 aaggagatta cgaaacatgg gtaggtgtct atgctcgtcc agagaataaa cctacctatt
    39901 tagatcctac gacgtcagaa gatgcctatt tacaaaatag gtatcgagta gatggtttta
    39961 agcaagactt tgcggagtgg tttgaatggg aaattgaaaa cggagaagta aaagaagaat
    40021 aagagtactt gttgtatcaa aataagccag tagaacaacc aaaccagtag ctagtaatga
    40081 caataatact gaggaatcgg atcattatgg tatgattgat atttctcttc cagaagatct
    40141 taagccagat cctgtaacaa ttggcaatag tgtcatgatt tttgattcat tagatgaagc
    40201 tatgtcatat ggttggaaag aaattaagga tgaaggtagt aattggtatg gcatgagatt
    40261 tggtgatggt gaagttgcca aaaaagctgg tattccaatt gggaaatgga cagttgattt
    40321 ccacgaagca ggttcttttt ttgttctgta attatagtgg gagggtaaaa tcattgatga
    40381 aatgtgttca gataagagcg ccagataaaa atagaagaga cagttcacgt cgttatcact
    40441 tttggtaacg gcgttttgtt ttattatata aaattctcag gaaaaggagg aattcttgtg
    40501 tatgcaaaaa cgaaaatgaa ttggttgaaa gcactcgcat tggtggcttt ttctcaattc
    40561 tgtttcttgg tgggaactgc tcaagcacat gcagaagaaa cgacggctat acaacctacg
    40621 atggaagcca ttgcccaagt cgcttctgaa gtgacagaag tccaaccagc agaagccggg
    40681 gtcccagctg gtgaagccac tgttgaacag gcccctgtga cagaagcgcc aacggtcaat
    40741 tccaaaacga ctctcgatca gacgattggg gaaacacaac acccagggaa tagtcctggt
    40801 acttcacaac cagttgaaga aactgcctca attacaaccc ctgcttcaga aacgtccact
    40861 ctagaaggag aaaaagctgc cgaagcaacg ccttctgtgc agccagagtc ttctgagaaa
    40921 caagcggaag aaaagaaacg aatagaagaa acagtggaac aaccagcggc tactgctgac
    40981 aaagaaggaa aaaatgagga aaacgttgaa aaaacaatct cttcaaccgc agctagtcaa
    41041 aatcaaccaa cgaaaccaaa caaagaatct acggctagta ttgaaaatca aaagaaaaaa
    41101 gagcagaaca ttccaaaaac aggtacacct acactgttag taacagtacc aaccaatcgt
    41161 tcggttcgtg ttcgccgtgc aaccaatgca gctgttttag gtggtcggaa aattgattgg
    41221 ggcgaaaata ttggtgttac ttctagtccg aacaatctaa acttcacttt aaattatatg
    41281 gttcgttttg agattaatgg acaagtggcg ttttgtattg agcctggtgt ctcagccgca
    41341 gaaggtcaag tttatacagc tactgctttg aaaaactatt tgaaaaattc aaatgtacgg
    41401 aaaaaaacaa gcttgatctc ttatttagga tatgtcacaa ataaagacaa atccgatgaa
    41461 caatacattg cggcacaatt tatgatttgg gaagctttgg gcacaaaaat cccaatcaaa
    41521 aatatccgtg ttgattatga tcgtcgaaaa gcagaaattc aacgtttgat taataacttt
    41581 ggtgaaaaag caacttttaa taatcaaaca catacggtaa aaattggcga aacgttgaaa
    41641 gtaaagaata aaaatgattt tttgaaatat gtgaaagaca ttcaaaaacc aaaaggtgtc
    41701 aatgtatcta ttcacggcaa tgaagtatgg attacagtca caaaagaggc accggataaa
    41761 gcaaaaattc aattgaataa aattaaagtt caaggtgcgc cattagccta tcgtcgtcca
    41821 ggagctcaaa caattggtgt gttacatcca acagaaccta atgcgtctgt tattaattta
    41881 caaattctaa aacaaggaaa cattcgtgtg tttaaagaag atgcggaaac tggtgtgaaa
    41941 gcacaaggtg cagcttcttt agaaaatgcg gtctatggtt tgtatcaagc agatgggaaa
    42001 aagattaaag aaattacctt gaaaaaaatt aacggcaaag tacaggcaga aattaaagat
    42061 cttgatcctg gcaaatatgt tttaaaagaa atcaaagcgc caaaaggtta tgtgctttct
    42121 gatgaagcaa ttgaaattgt tgttgaacct ggaaaaactg tcaatgcgac cgcaaaagat
    42181 caagtgatca aaggaaccat tgatttagtg aaagttgcta ataaagattt agtcgattca
    42241 acgaatccag ataacaaacc aaaattagct ggcattgaaa tcactttgac gtcaaaaaca
    42301 actggcaaag tggtgaaaac cgttgtgaca gacaatgatg gttatgctac ttttggtaaa
    42361 aataccgttg tctttgatac gtacattctt tctgaaacca aaggaaaaga agggtataaa
    42421 ctatttgaac cacttgaagt cacaatttct gaaaatgggc aaactttcca ttatgtttta
    42481 gaagataaag taattgaaca acgtcttaaa gtggtgaaag tggatcaaga aacaggaaaa
    42541 gtgattccac ttgctaatac agaattcaag atttttgata ctttagccaa tcgttatgtc
    42601 acaatggaga ttccaaatga tacagaaaca acggatatct ttaaaaccaa tgaaaaaggc
    42661 tttttcctaa ctaacggtac acttacttat ggaaaagatc gctatcgttt ggaagaaatc
    42721 aaagcccccg taaattacgt tttgaatcaa aacccattag tgttctcgat taccaatgat
    42781 acagaaccga tcaaagtgat ccattttgcg aaccgtcaag cacggaaaag tgtaaaatta
    42841 ttcaagtatg aagaatggaa caagaagaaa acgccgctcg caggtgtgaa ctttaccttg
    42901 tataacggta aaaatcaagc aattggtgaa tataccactg atcaaaacgg ggaaatttta
    42961 gtgaaaggtc tagttgccga tgactattac ttcttggaaa atgccccatt agaaagtttc
    43021 caaccaaata cagataaaca agcattcacg gttgcattca aacaaaatgc gccagatgat
    43081 ggggaaacgt tagtggtttc tgtacgtaat tacttgattc caccaaaact agaaacacaa
    43141 gcgtcaaata aagccgatgg tgaaaaagtg gttgatccat tagaaacgat cgtcattaaa
    43201 gacagtgttt cttataccaa cttgtttgtc ggaaaagaat acaccatttc aggagtattg
    43261 atgaacaagg caacgaatgc gccaatttta caagatggca aagaaatcac aagtaccttg
    43321 gcctttattg cagacaaagt caatggcaca aaagaccttg aatttgtggt taatgctagt
    43381 gttctgaaag gtcaaacgat cgttgttttt gaaaaacttt tccgtgatgg cattgaagtt
    43441 gcagcacatg cggatatcaa cgatgaagcc caaagtgtga aagtgaataa tccaaccgtt
    43501 cataccacgg ctgtctttga agacggattg acagtcgcag acccaacagg attgtttacc
    43561 ttaaacgata ccgttgaaat taccgagatt cttccaggaa aagcatactt ggtcaaaggg
    43621 atcttaatgg ataaagcaac cggtgaaccc ttgcttgtgc atggaaatac ggtagaaacg
    43681 agtgttggct ttattgccaa agcagaaaat gaaacggtga tcgtaccatt tacctttgat
    43741 ttgacaggta taaatggtcg tgaaatcgtc gtgtttgaaa gtctttttag aaatgatgaa
    43801 gaactagcaa accataaaga catcaacgac aaagggcaaa cggtacgagt aactaaccca
    43861 agtgtacgta caacggctac acataaaccc actggcttga aagaggttaa tccattaacg
    43921 aaagtcacca ttacagacgc tgtgaaatac cacgatttgg tcgttggaaa aacatacaca
    43981 gtcaacggtg ttctaatgga caaagtaacg gaaaaaccag tgctagtaga tggaaaagaa
    44041 gtcacaagta ccttaacgtt tgtggcagaa acaacggatg gtacagtcaa tctagacttt
    44101 attctagacg cacgtgcgtt gcgaggcaaa gaagtcgtgg tctttgaaga tctgtttaga
    44161 gaaggcgtat tattggcttc tcacgcagat attaccgaca atgaccaaac catcaaaatc
    44221 agtaatccaa ccattacgac gaaagcgacg aataaaaatg gcggaaaaga gatcttggcc
    44281 ttgccaaatc aaactgtgct tgaatgggtc aaagtagacg gtcttgcgat tggtcaaatc
    44341 tatcgcttaa ttgttcaagg ctacttaaca ccagacggca caccatttga aggcactcat
    44401 gcggaaaaag tctttgcggc cgataaagaa atgatggaat tcttatttga attcttagtg
    44461 gacggtcgca atcttgcagg aaaaggcttg agttttgcgg aatggctcca agcgaaaacg
    44521 gaagatgaga aagaaacgtt tgaagaagtg gcgaaacaca atgtagatct aacaaacaaa
    44581 gatcaaacgg ttcaaattgt ggaagcgcca aaaccaccgc aaccagtgaa accagaacaa
    44641 cgggttaaac cagctactgt tgtaccaatg ttgccaaaaa caggtgaaca aacaagtagt
    44701 atacttatgg ttcttggatt agtagtatta gtcattgctt taggtataac actttataaa
    44761 gtacgtaaag ccaaagatta gtcatgagga acaagcggtt aggattttta accgcttgtt
    44821 tgattgtaat gtagaaatat ttagaattta ttttggtttt taagaggagg aaaaacttta
    44881 tggcagaaaa agcattgcgt atgaagaaag agtttttagg tcaagtattt ttattgggtt
    44941 cacgggaacc taatccacca aaggaaatta atggtgtgtc tgggcgatat gttcaattac
    45001 aagcagagtg ttcgcgagaa gaacagcctg ctttttttgt ttatctcaca gctgaagagg
    45061 ataaaagatt acgattacca gaaaaagagg tgcgtatttc atttgaagaa gcttattttg
    45121 tttttcgtaa agaacgagtg aatagtcgtg aaacaaatga tatgggacaa acagagcgtc
    45181 gaacaactgg ctatcaagat gttggtgtct ttttaactgg tgtaaaaatt ggggaggttt
    45241 tgtaagatgg gattaaaatt tccaaataat tatgacatta cagaagcatt agatgaaact
    45301 tgtttaggag ccgtacgctt tggcgcatta gaagagtctg atcgtgtatt tgataatgaa
    45361 acaggcgatt atacgggaga aattcgatca cagcgagcac aattagtttt tggaaatcca
    45421 gatgaaccaa agattgcacg acgagttaaa tttccagcag atgtagattt gactggtttt
    45481 aaacgacgtg atcctgtgaa attaattgat ccagaatatc atgtggtata tattccagca
    45541 caagatggca atcgtgaata ttcagattta gtgatttatg cgaaaggatt agagaaagta
    45601 gaagctccaa caaataatcc taatatgaaa caatcacaag aaaaaggttt agatcaaaaa
    45661 caaccaagtg ttgattctaa ggaaaaagag aaaaaataag gtttttttga aagaatagga
    45721 aggagtcttc ctattctttt tatctaagat agaaggaagg ggagattttg aattcagata
    45781 aaaccaatca aatactttga gagattgtgc ttgttatcaa aatatccaac aattgattga
    45841 gtattttgga gacaatccaa cgatttttgt acaaacaaat gcatatattt gtgcggttat
    45901 tgggcagtgt atgtttttac gtgatcttgt tcgtttttca ttaccgtacc agtggaaaca
    45961 agatcatcag gaagtgattt ggattcgtat agtacgaata tgtaatatgt gtgcacaccc
    46021 ttataaaaat cgattaaatc tttttcgatt atgttttttt actaaatgtg atattcctgt
    46081 attagttgct ttttgtcaaa agtttttagc acaggaaaag taaaaacaga aaggaggaat
    46141 gtgacaattg aaagctcatt ttttcaagta tcgtggtcgg cgaattcgct atttcaatcg
    46201 ttatttatgg ttttgctatt atggtttctt tttgtttcca tttttgattc tgttaggttg
    46261 gtttagttgg aaagtatttt atccacgttt aagtacgttt tcgaattggc aaatgtatct
    46321 tattcctgga ataagtattg tgttgtattt gttgctggtt agtgggttaa ttttagggtt
    46381 gatgcattgg tcgcgactaa aagaaggata ttttgcctct gtttattggc gtcagttact
    46441 tgttcgaatg ttaattgaca atcggtttgt ttatacaaag aaacaagtta gtgagaaaca
    46501 aacaagggaa aaaatgagat taccaaaagt ttatttttat caaaagaaac aagaattagt
    46561 ggtttctttt cctttagatg gtgggcgttt tcacgaacga tttttaaaaa tgggtcattt
    46621 gttatctgaa gtatttttgc gtgatttaat tcgtgaagaa cgagaaaaag cccgaatcaa
    46681 ttatgtattc ctttcagatt ctggtcggat tcctattgat caatgtatag cagaaaatgg
    46741 acgtattcat ttaatgaaaa ctttggattg ggtatatgat caatcaccaa atatgttgat
    46801 tgctggtgca atcggtggtg ggaaaaccta tttattgtat tctttaattc aagcttgttt
    46861 aagtgttggg acagtagata tttgcgatgg aaaagcggca gatttagcag cattaggtga
    46921 cgtcgatgta ttcaaaggac atgtgtttta caaaataaat gaagaaatga ttatttgttt
    46981 acgaaatgca ttaaaagaaa tgaatcaacg gtatgcctat atgaaaacca tgaaagatcc
    47041 taaatatgaa ccagggaaaa attatgctta ttatgggtta ccaccgcatt ttatcttttt
    47101 tgatgaatgg gcagcttttt atggttcgtt ggatatggaa gcgagaaata gagtcgataa
    47161 attgattcag ccattagtat taaagggtcg tcaagcaggg atgtacatta ttttagcaat
    47221 gcaacgacca gatgcagaat attttccaag tggtgttcgg gataatttaa cattccgtat
    47281 ttctgttggt cgattgtctc ccattggtta tttaatgact tttggagaag attttaaaaa
    47341 taagccattt tacaacaaag atcaacctgg tcgtggatat gcttttccag gatttgatgt
    47401 acctgtagag ttttttgcgc catttgttta caaagattat cactttatca aagaatttga
    47461 gaaatttact gaaatgattg tctatgattt tacagtaaaa gaggatagtc aagatcaaac
    47521 gatgggagat gataatcagt tgttacaaga acaactagag cgccaaatgt atttagcaaa
    47581 agatccaaaa ggaacaagtt tttctgatgc gcatattttg taatcaacta aggaggtgaa
    47641 gttaaatggc agagagttgt tattatagag tagctacagc aatacgaatg attaatcctt
    47701 ctctttcttc cagaacgttt tatgattggt tgaatcgtat tgaacaagta actgattacc
    47761 gctttttgcg caaagaacgt gtttttacag gaaaagttat taatcaagta ttgctaacga
    47821 aaaaagatat agaacgattg actcgattgt atcattatcg agtagattta gaagaggatt
    47881 taactttgtc aatttatcgc gttttttctc ctgaaaaata tagtgaaata acaaaattag
    47941 atcatttaat tttgtagtta ttatctatcg ggagggctct agacgtagtc tggtagccgc
    48001 actctgcctg gcggtgcgca ttaaggctgc gaagcatggg cctataatgc gcactcgcta
    48061 gcagcgtgtg cagctcacaa agaggtcgtg cgcttgcgca cggcctcttt gtgtaaagcc
    48121 ccccgatata taatatgggg ggcagaaata acataacaca tagaaaaaag ttttataaac
    48181 ccttttgtat caagtgatta tctaaggtca gcagttgtac tacttttccc aaaaaacgag
    48241 ggggactagt tgatatatcg gtgtttctaa agggttaaaa aaatcgattt tgttatttta
    48301 taaaaggagc gagaaaatga caccgattga gctaaaaagc tacagaaaga agttaagtgc
    48361 aattcataat ataagtggag ataaaaagcc gctatcacaa gcaagatttg cgcaattgat
    48421 gggctgctca aaagattaca ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga
    48481 ttttgaacaa cgaatcaagg aacgctttcg attgtatatg aaaagcggaa tagatcttcg
    48541 agcaatgatt gattatttgc gtctttcctt ttttgggaca gactacaaaa cagtgattca
    48601 acgtgtatta cgaatggatc tgacagaatt tgaaacacgt ccaacgggct tgtatctttt
    48661 tgactgtctt tctgttcgtg ggaatatctg ggtgttctgg cattcaaaac gaactgtaac
    48721 agaaaatgta cttgtgcaat tttcaggaca aggttgccgg gaatatgagg aagtcatgcg
    48781 tgaacaacaa acagattggc gaacatggct atattccatt tggaaaaatc aaggaaagtt
    48841 ggaagctggt tatacacgtg tgcaatgtag ccgattcgat attgcgttag atgaactttg
    48901 gggattggaa acggaagaac atttcgatct ctttgaatta ctagaaaaac aaaaagcagg
    48961 tttattagaa atggacttta agagattcca gaatattggc ggttgttttt tagatgatgg
    49021 ctattttcga agtgaaggat tatctttgta ttttggatcg cgaaagagtc ctctcttttt
    49081 taatttttat gagaaacgtt ttgaaattgc gaaccgagaa aaaatttcag aattagaagc
    49141 attaacgaaa tatggtattt ataatcgata tgagttacgg ttagccaatg agaaagcaac
    49201 acaagcagta gaagcattta ttttaggtga ttcaccgaaa cgtttaggag agattggcgt
    49261 tggtttaatt aatgcaaaac ttattgtttg ggatagactg gaaagtgatg cacggattgt
    49321 tgataaacga tgggcaaaat tatttcgttc gatggaagaa ttggatttta cagtaaagcc
    49381 agaaaaattc tcattagatc gttcagaacg ctggtttttg aaacaagtag ctccgacatt
    49441 aaagttgtta caagaagcag atcgtatttt aggaagagac tttgtacaag aagggattga
    49501 taatgccgaa ctaaatgacg agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg
    49561 gaaaattgca tgaatgcata tacgacaaca gaatggctgc gcctgttgga tttaaaggct
    49621 gcaatcgaag cattaaatga aaagatggtt gatttgtctt attttcgttt tcgagttcct
    49681 tatattgaac aagcggtaaa agctggacgt tatcaggaaa aagagaactg gcaagaaatt
    49741 gcacgcttat tagaagttcg taagggatac gaacaagaac tcgaagagtt ggaatttagc
    49801 cgaaggaaag gaaggctaga attcattcgc ttttatcgat tttcattgcc aatacctgcg
    49861 attttagcgg ttaaaaaagg ctgcgataaa atgaagatat atgaaaactg tgtggcagca
    49921 cttagcagcg aaaaacctct tatggaagaa atttcattgg tgactgtcac ttgggaaatg
    49981 agtcgccagc caacagaaga acagacatat ctttctttag aagagattga gatagaatta
    50041 gaggaaattg gtcgctatgc cacttgttct acctattgtg gatcggtcat tagtattgct
    50101 ggtgtgattg tctaaatgaa aaaaattatg atttatgttg gtgcgtattg gtcacgtgat
    50161 ccaacagtat tagaaaatcc agaggcggta cactattgct tgcgccaatt attctatctg
    50221 tataaagaac gattagaatc gttgattcgt cagttaccat atactgacag acgtttagat
    50281 gaacttcttc taaggtatcc agcaatgtat aaacgacgaa aaaatagatt gttaccagaa
    50341 gagtatccca ttgaaaaaca tgaacttgaa gggcgatttg tggcttattt ctatgatgat
    50401 gttcgtatgc gcttagtaga acaacgaatg gaaatagaaa atgatcgcta ctattttatc
    50461 aattattgta agaagcgtaa gtatcaagta actgatgatt tttatgattg tattttacaa
    50521 gatggggaag tgattctatc caaaattgct ccaagttttc gtgaacttgt gccgattgat
    50581 tttttgaaaa aatgtcattt gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa
    50641 agtagaagcc aaatcggttt ctgctttttt atttttttta ggaaggagaa gatggtatgt
    50701 cactggaatt tttaggagag ccaattgaaa aggaagagtt cgtttcgcat tatatggatt
    50761 tgtttattca ggtgataaaa aactttgtgc gattgatgaa ttttatccac gcgaacaaga
    50821 ctatctagcc gctgaacgaa taaaaatcag tttattatgg gaaaaattca cagatgaaaa
    50881 taaccgaccg ccagattatc gctatttatc agattgttta acgaataatg tgctttctaa
    50941 agaataccta tttcacaaac gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg
    51001 ttatattgca ttattgcgta gtcaacagtt attaacagta gaacgatatg gtgcagagtt
    51061 tggttatgtc ttgcaagctg agcgtcatag agctacaaga tgctatgaaa aagaagatca
    51121 agtgattgat ggctatgaag aattatgtat tcgaaacaat cgctatttgc aacaacgttt
    51181 atatgaacaa ttgatgatgg atttttcaaa tctctataga gggtatgaat gttcgatgat
    51241 tcaagaaagg tagaagaaaa gggggaattt ttatgtggcg attattattt ttggtggtat
    51301 gtggtatggc attgttctat gtgtatcgtg tctatctcta tccacgaatg gaacgatgga
    51361 caagttggta tagagatcct ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat
    51421 tacttgttga attttcggat gggcgacaag cacagtatta tttttttgca aactatccaa
    51481 aatacaacac cagtgaacta ttgattcaat tattcaaaaa taatccatat gttgggttag
    51541 aagaaaacgg acgggagttc ttttatcgtt cagataatat tagtgcggcg tctatgaaca
    51601 aaacacgaat tgcataaaaa attggaggaa taatcatgaa aaaaacaaca ttagcagtcg
    51661 taacaacact aggaatttca ttattttcgt ttcaattagg gagttcattg gtttatgcag
    51721 atgaaactgt agaaacacct aagtcagaaa ttgtagaaac attgccaggg gaaggattac
    51781 cagatgttga gacagagcta aatggaggaa caacggaaaa accagcagaa cctgaacaat
    51841 tgcagtcaga gaaacctgaa aaagagccag tgacaccaga accagagttt cctgaatcaa
    51901 ctttaccgac tgattcgatc gaagaagaag gtgtgcatag ttcaacaaca acggattcaa
    51961 gtatagtcac aactccggaa caatcaggaa caaccagttc ttctgaaaag aatactgatt
    52021 cgtcaagtac ggaacagcca acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga
    52081 aacaacctgt tgaaaaatca gaagcaattc caaaagaaaa taaacctatt gttccagcaa
    52141 aagaagtcac agtatcggta accccaagcg gtgaaattac gacgaatact tctcaaggaa
    52201 tgagtgtacc gattgtcact agtaatgtag aggaattgac ccatattcca acaccaacca
    52261 ccccattaaa agtagcaggt gatcaaacaa ttgttggtgt aaaagatggt attccattaa
    52321 tccaagatag tgaagggaat ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa
    52381 gtggcaatat tgaaatcaaa acagcagatg gaaaaacaaa agtcttacca aagactggtg
    52441 aagaaataca tgttgcactt tctgttctag gaggagtgtt gacaagtatt gctggatttg
    52501 ttggatataa aagaaagaga aaaggaatag aaaatgaggg taattgaatg gactattttt
    52561 cagaaaaaca agcttatcgt tgtcaatcgt acgtactagt aaaaacatac tagaaggagt
    52621 agcttatgaa aaaacgacaa ctacggcgga aagaaaaagt ttatacagag aaagtaccga
    52681 agcaaaagaa aatccattca aaaaaagcag tgaaatggat ttggtgtttg gttttatttc
    52741 tttgtttttc agggggcttg gcattttttc aatccatgaa aacgaaggtt caagtgtcgt
    52801 ttttgaaaga tgaaatccaa caattacaaa agaaagaagt acaaagtcgg tcagaattaa
    52861 cgtacacacc tgaaattgaa tcctttatga atcgttttgt tgctttgtat atgaatacat
    52921 tcgataatca tgaacaagaa caacaacgtc aagaaacatt aaaaaaagag ttttatgcac
    52981 aaaactttat tcaagaacca ggaagtgttt caggtgttcg aaaattaact gctgcttcgt
    53041 ttattggatt aaaagaaatt gaaaccattc caactgctag ttataaagta acttatgata
    53101 ttcgctcgat gaatccagag agtaagaaag aaacaagtgt gacaatcaca caagtactca
    53161 atcttccctt ttctatttca aacaagggct gtcgtattat tgcttatcct tattttacgg
    53221 cactaccaaa gaatacagaa aaacaacgaa tgattactta tgatgacaca ttatacgaaa
    53281 cggttgatgc gtcggaagcg aaagatgttg aaggatttgt ggaagatttc ttagataagt
    53341 atgcgaaaaa caatgcaaaa gatatgtcat acatgatgaa agaacctgaa ggactcaatc
    53401 aaacagctaa agttgatcaa gtagagatga aagtattgcg ttataaagaa acgaaaaaac
    53461 cttttattgt aaaagcaacg gtcgtctttc gagatggtga tacgtcactt ttacaaaaag
    53521 aacaaatgac gattgtcatt acgaaaaaaa caaatcagta ttatgttgaa aaattaacac
    53581 ataattggtt ggataggaaa ggagaagaac ggaaatgaca ctgaagggaa ttgtagattt
    53641 tatattaacg caaggtggct attttttaat aatggtggtt gtttatctgg gattgcgaaa
    53701 ttttatgaaa tcaaaagtag gaaatgcatt aatatctatc gcagcaggtg ccgcagttta
    53761 tttcttctta aatgatccaa cacgtgtatt tgatgcgttt ggtaaaatca ttgaaaaatt
    53821 atttatggat taggaggata gtgaagtgga ttgggaacct tatgattatt cgattgttta
    53881 tgcggaacct tatcgcgtac aacagattac aagcaattgg cgtcttccat ttccagttgc
    53941 attagtcaat gcagcaactt ttttgttggt cgtaatcttt gaatatttat ttttacgttc
    54001 atttattggt tgggtcattt ctttttttcc accagcagga gttgtttttt atataggact
    54061 cccctattta tgtgtgttag cactggcaaa actaaaacct gatggaaaaa aagtgcattt
    54121 ttatttatgg gattggtttt gttatatgat tcgtatgatg aatggtgatt gtgtgtatta
    54181 taactgggac aaggtatcaa acaatgcatt ggaagaatta ctttttgtga ataagtatgt
    54241 ttatttagag gattagaaaa agggacaatc aactggttgt tcctttttta ttgggaggtg
    54301 aaattcattg gtgcttgtaa aagaaccagt aaaagcattc aagaaaaatt gtttgttaaa
    54361 tggagaggat tgtatctggg cctactatca tgtttttcca cgaacaattt caaaaaacac
    54421 accaaaaaag acacaggaaa taaaagaaat gatggctcgt ttactgttgc ttttagcaga
    54481 ttatgaagat gtggagttgg tgatgtatcc acgaacaatg aatttacgga cgaagtttga
    54541 cacattagga aagggatttt ctcccgatag tcaagcaatt ggtgcgtatt atgcaaaaga
    54601 aacagtgaca ttgttggaac gagaaggtca agtctatcgt ccttcattta ttttaggaat
    54661 caaagtcaaa gaaaaagcaa cggtggagag ttttcatgat gtaataaatc taatctggtt
    54721 agatttagca ggaagtttag cacgcttatt tggattagaa gtagatgatt tggaaacttt
    54781 gttttctgaa agtgatcctt atgtaaaaga agtgacacaa ttactttata gcttttctat
    54841 tcgtccctta gtaaaaaaag agctgttgta tctcaatcgt ctgcaatata ttcgaggaat
    54901 ggctcacaaa gtagaagaac aaaataattg ggaagtactg aaagacaatc aaggaacgta
    54961 tgtacgtata ccgaaggaac ataaaggcct tcttcaatta gaagatgagt tagggagtag
    55021 ttatttagca ttgttgccta ttggggaaac acctgaaaat atgagaaatt gtgatctatt
    55081 tcaatttgct caggatcttt ctttcccagc agaattgcga atgaaaattc actatccacg
    55141 cttgaaagga cagggaggta ttggtttaaa actgaattgg ctatcggaac ggttcaaaac
    55201 agagcataag gaattggttc aaaatgatga agaacctagt gaacgcttat taactgttcg
    55261 aggattagta aaacatttaa agcaacgagt agataatggg caacctgtcg tcgattggat
    55321 cgcatgtttt attgtatacg gtcaaacggt tgaagaagtt cgtcaaaata gtgcaacggt
    55381 tattcaacaa cttcatacga ttatccatat ccaccgtgca aaaaatgatc aacgagaatt
    55441 gttctataaa tgtttattag ggcaaccatt gggacggcag ttacattgga agcaccgaac
    55501 aactgtagaa gcagttggcg aatggttgtt ttcagcagta tcagaattag gtatggaatc
    55561 cggctggtat attggtcggc aagatacatt aggggatggt ggttctcgag gagaaaaaac
    55621 accattagaa gaattaattt atgcgtcaaa tcgttttgtc tttttgaatc ttctagccat
    55681 tgcggaagga atcaaaggtg cgttgtttga tgcgcctcat gtagcagtaa ctggaaaaac
    55741 cggtaaaggg aagacctttt tagttggctt gctctttttg tatagttcgt ttatgaatgt
    55801 acaaagttta tttgtggatc ccaaaggaga aaagcgcaaa tggtttacga aactcattca
    55861 agacccgtat tatcagaaac attacccttt gtttgtagaa catttgcaaa aaatgagtta
    55921 tgtcacgtta gatgctacaa atccccgtaa ttatggtgta ttagatccaa ttgtttgttt
    55981 atcccgagta gatgcgaaac aagtagccca ggatatgatt gatgagttaa gtccgttagg
    56041 taccaatcac cttttaaaag gggcggtatt aaagggaatc caagaagttt tagttcaaaa
    56101 agaagccgga caacaagttg gcttgatgca tgtggtcgac tatttagaac aaatggaaca
    56161 aaaagaggtt cgagaatatg gtgagttttt acgcttgacg gtagaagatt cgattttacg
    56221 tttaggattt tcttatggag aaaacccggg attagacttt aatgccaaaa caacgatttt
    56281 agagatccaa gatttgaaat taccaaatga caatgtccga ccagaactat atacagatgc
    56341 ggatcgaaag tctttgtgtt tgatgattag tttaggtcgt ttttgtgaaa tgtttggaaa
    56401 acgagatagt agtaagaaaa cagcgattta ttttacagaa gcatgggtat ttaataattc
    56461 gaacgcagga cgtagtatta ttgcagcaat ggcacgtgtg gggcgttccc agatgaatca
    56521 attagtgtta gatacacaat ttattggtga cttaggttca gataaagaaa aagggaattt
    56581 tggtgtcgtc tttgcttttg atgaagacag tgagcgagaa aagattttga atcatttacg
    56641 tttggaagta aatgaagcga acttagctga aatgagccac atgattaaag gacagtgttg
    56701 gatgttagat ccctatggac gtgtaggaaa actcaatgta cacagtttgt ttgaagaaat
    56761 gaccgctgca ttacaaacaa cggaaaaaac aagtcactct caagtagaag aacaggatac
    56821 gttaatcatg caatagaaat gaggtgaaac aatggcttat ataaagcata aggaaaagaa
    56881 atggtgcgtt ttgttttttt taacgattgg attcggactg ctttttgttg gtggattggt
    56941 gtatgcggca gaaaagcagg tggatcaatc gatctatgag attgggaaat ttcatattga
    57001 taccttttct tcttatttat ctgatagtga attttcatta ggcaaaatgt tatttggggc
    57061 aaatggcaca gattttctaa aaatgatgac gaatatgttc tttagtttaa gtaaattgat
    57121 ttggcaaggc cttgattttg tcattgagaa gctctatgaa ggagctgcaa tgaacgagtt
    57181 aattcaccag tttttcactt tttcggatac tatttattca aaaatatacg atcctattgg
    57241 tgcggggatt gtcgtcttgt atgtgttata tctatttact cttcgtatat ttagagggaa
    57301 acattacgca aaaatggtgt ttattcgatt tctcttcgtt gtcatttttt caatggtttg
    57361 gtttggctat ggtagtaacg tacctagtaa aggagaagct tttaccaaag ggttaaatga
    57421 tttgtccgtg gaggtagaag gctttatttt ttctgctaca aatagtctag atgaattggc
    57481 gacaaaagat gtcaatggtg ttttagtgcc aacgacacaa aaggaagcca ttcaaaaagt
    57541 gcgccaactt tattataaag cggctgttgt tgatccgtat atattgttaa attatgggac
    57601 aacaaattta gaagaattgt atcaagcaga gattgaacca caagaatttc tagccaagga
    57661 agcgtcaagt gaagaattat ctgatattga gacaaaagtg accactgctg caggagaaga
    57721 tagagggaaa aagaaggctt atcgtgtcta tattcaacca actaaagctg tttataaagc
    57781 agtcgttggt tctatggtgc cattgcttaa tctaagtatt ggattaccac ttgtagtgat
    57841 tggcatgatt cgttttatct ttcaaatgtt ggtgttgtgt ttattacttg tgattccttt
    57901 ttcattactc gcttcttttg ttccagtatt tgattatatg ctcatgaata ccttaaagtc
    57961 ctttttgggc ttgatgtttc aaaaatcttt ttacagtgtg attattttgg tggcattttt
    58021 gatctataac atagtagacg atttaattcc aatgaatact gtttttggtt ttttaggaaa
    58081 tatgtttgtc aaagcactcc tatcaatttt actcattgta aaacggaaag atttattaaa
    58141 gaaactaggg ttaggagctg cagatcaaac tataaacaac acgaaaaaca tagcaagtca
    58201 ttctttgtct caaatgaaac aactgcctgg tcaactatca actgctggac aaaatttggc
    58261 aatcaaaggt gcaggattag cagggaatgt gtatcgagca acgaatccac tcgcttctgc
    58321 agcgatacat ggatttcaaa agtttcaaca aaaacgtaca ccacaagaat cggtaaaagg
    58381 gaggcaagtg gttaatccct ttgaactagg tgggcgttca aatcaagcct tgccttatag
    58441 tggtcgtcat gttcgttatc atggggtaga gcctgaaatg tcttctacca aatcgaaaac
    58501 agagtggaat tctggtcttt caaatggttt gattccaaat tcgtccatga attcagtaag
    58561 accaaaacaa caggtacaat cattggcaca attgagtaag caacaaggga ataatcaaag
    58621 aaaaccattg ttaaataaag gtatcgcttt tgttggtcaa tcgattccgt tgccttctgg
    58681 aaaagtaccc gtgccacaat taacagctgc tggttctctt tcacaacaga ttcgccaagt
    58741 gaaaaatcag gcgaaaaatg ggagttatcc agcaatgcag cagttattga accaatactc
    58801 tgttcctaat tcgtcggtag ccactctatc aggaaatcgt tctgtgcaac aaccggggca
    58861 acgttcgtct gaaagtaaac cgtcgatttc cgcaccaaaa tcgttacaac ctgcattttc
    58921 ttctttagat aagccaacag agcaatcgga aaaaatagaa aaggatccta aaacactgcc
    58981 gattttggac gcaaaaccag gaactgattt tactttacca aaaggacgaa cagtccaaaa
    59041 accattatcg aagaaaggat gaggaagaaa tgaagaaagg gtgtctaggt tgtcttcttt
    59101 tctttattct tccctttttt ctattgccat tctttttttc aggagaactt tctgagcatg
    59161 gaggagaagc tacaggtcta gctgtcgctt ttaatgggga atataccgaa ggattaccga
    59221 ttttttcaga gattaaagga cgtggtccaa tcacagatga acatgcgcaa gcagcagttg
    59281 gtgcagctgt aaagtatcag ttattaccga gtgtgattct ttctcaatta ggctatgaat
    59341 cagcttatgg acagtcacaa tctggaagaa acgatacgaa cttttttggg attacctggt
    59401 ttcctggttg tccctaccca caaggttctg cacgtggaat tggtggttct gaaggtggtt
    59461 tctatatgaa gtttccgaac ttaaaagctt gttatgacta ttatggcttt atggtggcga
    59521 gccaaagcaa ctttaatcaa tgtgtgggca ataaagatcc tggaagttgt ttattgattc
    59581 taggtcgtgg aggctatgcg gcagcaggta ttaccgaagg gagtccgtat tatcgaggag
    59641 caatgagtat cataacgtcc tataacttaa cggaatatga tacttttgcg atcaagcatt
    59701 ggaatagcct accaacaaaa aaaacttcgc ttattgcagg aaaaagtaaa ggcaatgcga
    59761 aggttttgga tcggatcatt ggacgatccg taaataatgg ggaatgttat ggtggtacgg
    59821 catggtatgt atctcaatta ggtggcccac agttaatggg ttctggacac atgtttgcga
    59881 tgttaatagg ggaagattat aactggacaa cctatggttg gcaagtaatc atgaacccaa
    59941 aaccaagtga tttacaagca ggagatgtgg tgaattggca agcaggtggt gcattgtctc
    60001 ctggaatcta tggtcacacc ggaattataa cagatgtttc atatggcgga caacatttct
    60061 ctagtgtgga acagaatgcc gagcaaggac ggattatggc tcggtatcaa cgcacgtaca
    60121 atcaaacaaa aattcgtagt ctggttcgta aggtgaaata agaaaggcag tgactagaaa
    60181 cgtgaaaaaa gggataattt tagtatttag ttggttatgt ttgataggtc ttactggttg
    60241 tcattggttt tcttctgaaa aacaaaaaac acaattgaga acgacagaag aaacaatcga
    60301 agcagtaaaa gaaacaagtg gaactcttca aagtactgaa agtaacagtc aaattggttc
    60361 attagaagac gagacagcgc aacaaatgca aatagatgaa atgacaaaaa atttcttaaa
    60421 agattttgct agaaaatgga gtaatttcac agatgtttat aaacgcaatc aagctgtgag
    60481 ggactatatg acagatcgtt gtattaaaga caatagtatt gatgtagacc cgcatgtaca
    60541 aatgaaaaca actgggaaac tttaccaggt gacacaagat atagagaatc cggatcaata
    60601 tttgttattt ggagaagaaa caatgaataa ggttactcaa tttgtattac ttcaattgaa
    60661 agtaggtcaa gaagctcaaa agattgatgc gatcaagatt tattatgtac ggagtgcgta
    60721 ttaaaataaa aaatgaacac tcatatttat tatacaccga agaaatagaa aaaaacagac
    60781 tgttttttta agaaaaacta tgtcattctt tacttgaaaa aagttgttat aggacagaaa
    60841 ggataaaaca aaaacggaaa aaatatgtct tatgaataac tataagaact attctatttt
    60901 ttaggagatg gatacgagat gaaaaaacta attggctata gtgtgatgtg tattggattt
    60961 gttggtgtgg gattgtttgt atcgactgaa tctgcttctg cggctgaatg gtataatcct
    61021 atctggtata atccgaacat tgaatgtcaa aaaggctatc cgtatggacc gacaaatctg
    61081 aaaaatggaa aatgtagagt aaattggaat ggcgttgtag atagtgtaat tactggttca
    61141 atggactctg ctctacatgg ctttacgggt cactagaagg aggaagaaaa tgtctgaaga
    61201 gaaaaaagaa atcgttgaat cattagtagc tttaaaagat tctctttcta agattgaata
    61261 tgttgatagg caagaaattc aaaaactaat tgatgatact attattgaaa tccaagatgc
    61321 gcgttgtgaa ggtataaaaa tttctgtagc tttatctaaa gtaatagaaa aaatgaaccg
    61381 ttcattagcg tttaatggat tgaagctaga tagacaaact agtctgatat gggatcattt
    61441 aaaagacttg tatgacaagt ctaaaagaag tgaacggact gctgtatcaa tcttaaaagg
    61501 cctttgggga atgaattcat aaacaagata tttaaaaagt aacttatttt ttatggagga
    61561 gaaattatga aaagaataat taaaatattt ggtgttttag gtgttttctt attaggttta
    61621 agtacttttg ttagtactgg aacaagtgtg tatgccacag aaaaagtgaa tacagttgat
    61681 ttagaaataa agaataaatt agtagatgaa ttaacttttt attttgatac agttggtttt
    61741 ttagacgaac atggtgtata ccatataaag gattttggtg ctattcgtga acgaatcagt
    61801 caagataacg aacaaggaag agcagcaaga gtcttttatg aacatattat tgttcctaga
    61861 atggagaaag ttgattggaa acgatatgct ggatgtgtag ccattaattc tcttcctgga
    61921 ggaggagtgg cttgggctat aggtacgcag ggagatttta ttgaagcatt aaaagctttt
    61981 aattttgaaa aagctgcgga tttattatta aaaattgcag aaaaacaatt aggaaaagct
    62041 gcagctaaag agttagctaa ggtaaatatt gtagcaggaa ttgcagcagc tgctgctagc
    62101 tgtgcattag agtaaaagtt tatgaaaagt ttagaacaag agcatatggc ttttaaacaa
    62161 gcaatgttta aagaaaatat ctatttaaac cataactata ttcgtgtttc taaggcatgt
    62221 tcaccagtat tgaatatgct tggaggtgga aatggattat atcatttact gtttgtcgat
    62281 gtttgttggt taattttttt accagatgaa ctagtt
//
LOCUS       DAFLWZ010000007        60720 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000007 DAFLWZ010000000
VERSION     DAFLWZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.007"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(90..2162)
                     /locus_tag="L1V38_000465"
     CDS             complement(90..2162)
                     /locus_tag="L1V38_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1315042.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(2095..2472)
                     /locus_tag="L1V38_000466"
     CDS             complement(2095..2472)
                     /locus_tag="L1V38_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBN1315043.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(2601..3179)
                     /locus_tag="L1V38_000467"
     CDS             complement(2601..3179)
                     /locus_tag="L1V38_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1315044.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            3311..4603
                     /locus_tag="L1V38_000468"
     CDS             3311..4603
                     /locus_tag="L1V38_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1315045.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(4663..5781)
                     /locus_tag="L1V38_000469"
     CDS             complement(4663..5781)
                     /locus_tag="L1V38_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBN1315046.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(5795..7216)
                     /gene="arcD"
                     /locus_tag="L1V38_000470"
     CDS             complement(5795..7216)
                     /gene="arcD"
                     /locus_tag="L1V38_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBN1315047.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(7462..8583)
                     /gene="mnmA"
                     /locus_tag="L1V38_000471"
     CDS             complement(7462..8583)
                     /gene="mnmA"
                     /locus_tag="L1V38_000471"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBN1315048.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            8987..9586
                     /locus_tag="L1V38_000472"
     CDS             8987..9586
                     /locus_tag="L1V38_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBN1315049.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(9724..11010)
                     /gene="efmA"
                     /locus_tag="L1V38_000473"
     CDS             complement(9724..11010)
                     /gene="efmA"
                     /locus_tag="L1V38_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBN1315050.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11281..11625)
                     /locus_tag="L1V38_000474"
     CDS             complement(11281..11625)
                     /locus_tag="L1V38_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBN1315051.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(11762..12907)
                     /locus_tag="L1V38_000475"
     CDS             complement(11762..12907)
                     /locus_tag="L1V38_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1315052.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(13087..14061)
                     /locus_tag="L1V38_000476"
     CDS             complement(13087..14061)
                     /locus_tag="L1V38_000476"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1315053.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(14141..15016)
                     /locus_tag="L1V38_000477"
     CDS             complement(14141..15016)
                     /locus_tag="L1V38_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBN1315054.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            15146..17053
                     /locus_tag="L1V38_000478"
     CDS             15146..17053
                     /locus_tag="L1V38_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBN1315055.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(17594..20872)
                     /locus_tag="L1V38_000479"
     CDS             complement(17594..20872)
                     /locus_tag="L1V38_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBN1315056.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(21143..21688)
                     /locus_tag="L1V38_000480"
     CDS             complement(21143..21688)
                     /locus_tag="L1V38_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1315057.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(21700..22392)
                     /locus_tag="L1V38_000481"
     CDS             complement(21700..22392)
                     /locus_tag="L1V38_000481"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBN1315058.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(22411..22695)
                     /locus_tag="L1V38_000482"
     CDS             complement(22411..22695)
                     /locus_tag="L1V38_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315059.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(22708..23271)
                     /locus_tag="L1V38_000483"
     CDS             complement(22708..23271)
                     /locus_tag="L1V38_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1315060.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            23499..24161
                     /locus_tag="L1V38_000484"
     CDS             23499..24161
                     /locus_tag="L1V38_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBN1315061.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            24285..25481
                     /locus_tag="L1V38_000485"
     CDS             24285..25481
                     /locus_tag="L1V38_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBN1315062.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(25582..26958)
                     /locus_tag="L1V38_000486"
     CDS             complement(25582..26958)
                     /locus_tag="L1V38_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1315063.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(26995..27862)
                     /locus_tag="L1V38_000487"
                     /pseudo
     CDS             complement(26995..27862)
                     /locus_tag="L1V38_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(27951..28976)
                     /locus_tag="L1V38_000488"
     CDS             complement(27951..28976)
                     /locus_tag="L1V38_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1315064.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(28994..29668)
                     /locus_tag="L1V38_000489"
     CDS             complement(28994..29668)
                     /locus_tag="L1V38_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315065.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(29852..30745)
                     /locus_tag="L1V38_000490"
     CDS             complement(29852..30745)
                     /locus_tag="L1V38_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1315066.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(30819..32516)
                     /locus_tag="L1V38_000491"
     CDS             complement(30819..32516)
                     /locus_tag="L1V38_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1315067.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(32509..33822)
                     /locus_tag="L1V38_000492"
     CDS             complement(32509..33822)
                     /locus_tag="L1V38_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1315068.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(33822..37859)
                     /locus_tag="L1V38_000493"
     CDS             complement(33822..37859)
                     /locus_tag="L1V38_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1315069.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(37872..38330)
                     /locus_tag="L1V38_000494"
     CDS             complement(37872..38330)
                     /locus_tag="L1V38_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1315070.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(38628..39146)
                     /locus_tag="L1V38_000495"
     CDS             complement(38628..39146)
                     /locus_tag="L1V38_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1315071.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(39148..39765)
                     /locus_tag="L1V38_000496"
     CDS             complement(39148..39765)
                     /locus_tag="L1V38_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1315072.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(39762..40616)
                     /locus_tag="L1V38_000497"
     CDS             complement(39762..40616)
                     /locus_tag="L1V38_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1315073.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(40613..41524)
                     /locus_tag="L1V38_000498"
     CDS             complement(40613..41524)
                     /locus_tag="L1V38_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315074.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(41565..42899)
                     /locus_tag="L1V38_000499"
     CDS             complement(41565..42899)
                     /locus_tag="L1V38_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1315075.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            43107..43937
                     /locus_tag="L1V38_000500"
     CDS             43107..43937
                     /locus_tag="L1V38_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBN1315076.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(44181..44463)
                     /locus_tag="L1V38_000501"
                     /pseudo
     CDS             complement(44181..44463)
                     /locus_tag="L1V38_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(44621..44815)
                     /locus_tag="L1V38_000502"
     CDS             complement(44621..44815)
                     /locus_tag="L1V38_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315077.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(45320..45505)
                     /locus_tag="L1V38_000503"
     CDS             complement(45320..45505)
                     /locus_tag="L1V38_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315078.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(46355..46696)
                     /locus_tag="L1V38_000504"
     CDS             complement(46355..46696)
                     /locus_tag="L1V38_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1315079.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(46696..46926)
                     /locus_tag="L1V38_000505"
     CDS             complement(46696..46926)
                     /locus_tag="L1V38_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1315080.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            47213..47551
                     /locus_tag="L1V38_000506"
     CDS             47213..47551
                     /locus_tag="L1V38_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315081.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(47756..47995)
                     /locus_tag="L1V38_000507"
     CDS             complement(47756..47995)
                     /locus_tag="L1V38_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1315082.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(47971..48318)
                     /locus_tag="L1V38_000508"
     CDS             complement(47971..48318)
                     /locus_tag="L1V38_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1315083.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(49050..49631)
                     /locus_tag="L1V38_000509"
     CDS             complement(49050..49631)
                     /locus_tag="L1V38_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1315084.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(49814..50440)
                     /locus_tag="L1V38_000510"
     CDS             complement(49814..50440)
                     /locus_tag="L1V38_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1315085.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(50462..51793)
                     /locus_tag="L1V38_000511"
     CDS             complement(50462..51793)
                     /locus_tag="L1V38_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBN1315086.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(51948..52349)
                     /locus_tag="L1V38_000512"
     CDS             complement(51948..52349)
                     /locus_tag="L1V38_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1315087.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(52435..52641)
                     /locus_tag="L1V38_000513"
     CDS             complement(52435..52641)
                     /locus_tag="L1V38_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315088.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(52736..54238)
                     /locus_tag="L1V38_000514"
     CDS             complement(52736..54238)
                     /locus_tag="L1V38_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBN1315089.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(54256..54711)
                     /gene="argR"
                     /locus_tag="L1V38_000515"
     CDS             complement(54256..54711)
                     /gene="argR"
                     /locus_tag="L1V38_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1315090.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(54809..55426)
                     /locus_tag="L1V38_000516"
     CDS             complement(54809..55426)
                     /locus_tag="L1V38_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBN1315091.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            55647..57020
                     /locus_tag="L1V38_000517"
     CDS             55647..57020
                     /locus_tag="L1V38_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315092.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            57095..58207
                     /locus_tag="L1V38_000518"
     CDS             57095..58207
                     /locus_tag="L1V38_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBN1315093.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(58279..59916)
                     /locus_tag="L1V38_000519"
     CDS             complement(58279..59916)
                     /locus_tag="L1V38_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBN1315094.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(60084..60692)
                     /locus_tag="L1V38_000520"
     CDS             complement(60084..60692)
                     /locus_tag="L1V38_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1315095.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        17322 a        12920 c        10701 g        19777 t
ORIGIN      
        1 atttcacaaa aatttgagaa gcaattttcg taaattcctt cttatttctt gaagctgacc
       61 acttctatca caacctcttt catatcttat tacttcttca ttgctgcttt tagtgctgct
      121 gctaatgggc tttcttctgg ttcttctgct tgtgcatatt ttttcagcaa gcgtcgttct
      181 tcatgtttgg tcattttctt cttctgctct tttttatcaa gcaatttttc tgtcgttcca
      241 tcgtatttac aacggaaata agcaccgttt ttaccttcga tgatttccat tttccggtga
      301 cattgcgggc atcgatgatt agagactttt ggatcttttc ttctgcggta gttgcaatct
      361 gaattggtgc agacatagat tttgccgtca cgtgtgtttt tctcgcgcag attggcccca
      421 cattctgggc atttcttttg ggtaatcgag aaatcttgat attcttgttt gcttgatttg
      481 atctcattca ccaagcgttt tgtttctttt tcgattccat tcaagaaggt tcctgcttgt
      541 ttctttcctg cagcaatagc ttcaaggtct ttttcccagc tttctgtcaa atctggtgtt
      601 actaaagagg gatttaccaa tactaataat tgcttacctt taggagatac ttgcagtcct
      661 tgaggggtac gttccatcag ttcagatttg attagtttct cgataatctc tgcacgcgta
      721 gctggggttc ccagactgta tttttccatt tgaccaagca agcttgcttc tgacaatggt
      781 ttaggcggtg cagatagttc ttttttgatg gcgaaatcgg gattgattct cattcctttt
      841 tcccatttga ctgtttccgt ctcagtttca gtttcgcctt tccatcctgc ttggacgaca
      901 cgattttgcc gaaaaatgaa tcgttcttta ccaaattcaa ccgtaacttt tgtttggctg
      961 actttatggg gttgagcaaa cagtcctaaa aaacgagaga caatcatttg atagattttt
     1021 cgctcttcat tacttaattt ttcataacgt gctctgtttt cagttggcaa aagtgcatgg
     1081 tgatcggtca ctttactgtc ttggaatact tttgtctgtt ggacgatggc tccgtttttc
     1141 aaatactgct tgacctcagg agcaaagtcg ctgactgctt gcaatcgttc tttcatcgta
     1201 cttttcatgt catttgtcag atatttgctg tctgtacgcg gataagtaac gatcttatgg
     1261 gtctcataca aactttgtac aagacttaat gttttctttg cagaatagcc atagcgttga
     1321 ttggcttctc tttggatctc tgttaaatca taaggcaatg gcgcagattc cgtttttaat
     1381 ttttcttgga cttctgtgac agttcctttg cttgtactga tcaattgaac aagtttttgt
     1441 gcttcttctt gtgtttttaa agcaaattga tttttttgaa gcattttggc ttgttctttt
     1501 ccagcttgca acgtgatcgt gaaatacgtt tgtggacgga actgctcgat tttcttttct
     1561 tggtctctca ctaatgctag tgtcggtgtc tgcacacggc ctgctgataa attatccgcg
     1621 tacttcacag ttaaggctct ggtcacattc aatcctacca gccagtccgc ttttgcccgg
     1681 gcaagagcag attcatacaa tgcatcatat tctttcgcag gtcttagttg cttgaatcca
     1741 gttttgattg ctttatctgt ttgagaagag atccataacc gcttcactgg tttattgaaa
     1801 tgcacatact ctaagatcca gcgagcaaca agttcccctt ctcttccggc atctgtcgca
     1861 atgactgctt ctgagacatc ttttcgctga gccagctgct tgattgcttt taattgatgt
     1921 cctgttttag gaagtggttt gattcctagt tttttaggga tcattggcaa cgtgtccatt
     1981 tgccagctct gccattcctt attcagatct tccggcattt tcaatcctaa taaatgacca
     2041 agggcccaag taacgatcac cttgggtcct tcataataat ttttgtgctt ttgattagca
     2101 ccaagcacct tgcttaggtc tttcgcaacg cttggttttt ccgctagaat tagttgtttc
     2161 ataaaattcc tttctgcttt ctactgtgat gggctgatga tttttcaaca acgcaagtcc
     2221 cttgtattgc tgtaaatcat cgtcacactc ttcacaccag cgctcatctc cgtcattcca
     2281 aaaggcgctg agaaagttac tttttgcatt gatatattca taattttgat ggatttcgtt
     2341 ccattgtttt tcgtacgctt gtcgtgcttc ttcgaaagac tcgaatgttt cttcttcttc
     2401 aatatcttct tcccagtctt caaaaaacca ccaaggctca ttgtccccga acatggtaat
     2461 tacttgatac atactcgtgc tccttctttc agcttttcta gactcatctt agtcactttt
     2521 caagaaagtt gcaagaattt tctcttataa aagggtcatt taatgaacat cttaaaattg
     2581 ttacaaatga atctgattgt ttaaggcaaa gtagcgataa agttattgat catccaaaaa
     2641 tagctgtctt ctggatcgat tgttggttct tttgtaaagt atcctaaaaa acgtaaggaa
     2701 agataaccgt ggatcatact acgaagttcc ctgcttcgat gaactttttc ttctttcgtt
     2761 aattgaaaag cctcaaatat ctgcaaaatg atctgattcg tttcatggat tccatctaat
     2821 aaaacagctt cattggtatg cggtacactg atcagtaact catacactgc ttgatttgaa
     2881 aaagcaaagg atcgataagt ttctgcatag atctgcagtg cttcctgacc actttttccc
     2941 acaagagccc gtcgcagctg gtcattaagt tcctgcagaa gtttcgctgt tagcgctgtt
     3001 ttgacatcac gaatattttt gaaatggtta tacagcgagg gagccttgat atccaagcgt
     3061 ttggctaaat gctgaaaggt tatttgctga acatccatct cttctgctag ttctcgaaag
     3121 cagtcgatga ttttctcttg agacagattt ctttttttca tttccatgtt tcctctcata
     3181 aaataaatcc ttcactcttt cagtttacca cgaaaaagaa agagaaaaaa gagactttca
     3241 ttgataaact acatattgta gtttataata aagagctgta gatgaaaatt ttcagaaaga
     3301 aggagtctaa ttggctgcaa gaataaagga aaaattattt aggaaaagag aaacttggga
     3361 acaaaacttg tttgtcttat ggtttggaac atttatggct ggtatcggat ttagtttagt
     3421 catgcctttt atgtcacttt acatagatac gttaggtaat tatagtacgt cacaattgaa
     3481 cttttggagc ggattgactt tttcatctac tttcttggtg actacgctta tctctccttg
     3541 gtggggaaaa ttagccgacc aaaaaggaag aaaattgatg ctgttgcgtg cttcattagg
     3601 aatggcaatc gtcatttctt tgatgggttg cgtgactagt gtgtatcaat tagtcgcatt
     3661 gcgtctgctt caagggattt tttctggtta tatcagtaat gccactgccc ttgtcgcaac
     3721 tgggacgcca aaagaaaaaa gtggtcaagt tcttggaacc ttagcaactg gttctgttac
     3781 aggaacatta cttggaccgc ttcttggcgg gatctctgct tcagcgtttg gctatcgccc
     3841 tacctttttc attacaggga tcatcttatt tttcgtcttc ttgttgagtc tgtttttcgt
     3901 ccatgaaaaa tttgtcccag tgaaaaaaga aaacatggtt tctgccaaac agattttcaa
     3961 agacttgaaa tatccacacg tcgtcatcgg tatgttcgtc acaacgatga tcatccaagc
     4021 atccaacaat tccattagtc caatcatcag tctgtacatt cgccaattgc tgcatggaca
     4081 tgggaatgtt acgttgatca gcggaatcat tgcttcgata cctgggattg ccactttgat
     4141 agccgctcca agatttggtc gcttaggtga caagattggg agtgaaagaa tacttgcgat
     4201 tggtttgggt tttgcgattc tggtttatat cccaatggca ttcgtcacga atgtttggca
     4261 attagctgcc ttacgttttt tgattggtat ctctgatgct tgtctgctcc ctgctgtcca
     4321 agcattgatc acaaaatatt cgcctcatca agctgctgga cggatcttca gttataacca
     4381 atctttccaa gcaactggta acgtagtagg gcctatgatc ggctccagtg tttccagtgc
     4441 atttggttat cgcggcgtct ttctttcgac ttctcttctt gttttggtca acttcttgct
     4501 tgtacgacac aatacacaag agatccatca gcaagaaact gcagaagaaa aagcttcagg
     4561 agtctccata gcttcagggc actctccttc tcatagacaa taagcgtaaa tgaaaaacac
     4621 tgcttgaaca gttgtcacag actgtccttg cagtgttttt gtttaggcct gttttttcaa
     4681 gaactcagat aagaggaata atcccttttc caaggtttct tttttacaac agtaacctag
     4741 tcgggcatgc ttcggtaaat caaaggcact tcctggtact aatagtactc ctgtttcttc
     4801 taataaattg atacaaaatg tctggtcatc ttcttcgatg gctaatttaa tgaaagaagt
     4861 agagacgtaa ttgggagcga caagttcaac tttcggttca ttggctaccc attgttttaa
     4921 aatcacaagg ttctctgtaa tgatcttttt gtttcgcgcc aatatttttt ctttattctt
     4981 caatgcatgt acagcaagat catctgacag gactccgccg caaatcatcg tgtagtctcg
     5041 atactttcga aaaacttctg ccaactcagg tccagtagct gtccagccaa tacgaatacc
     5101 tggaatggag taggttttgg atagggaatt ggttgctata cctttttcat agacatctac
     5161 gatcgacaag aattcacctt tatccgttaa aggcgcatat acttcatcta tcaatacata
     5221 tgcatctact gtacgagcaa tttctgcgat tttttctaaa gttttccgat ctagcaatgt
     5281 gcctgtagga ttgtttgcac tattcaaaca gatgattttt gtttcaggtt tgactaaggc
     5341 ttctagctgt tctaaatcaa actgccaatc ttcttcttcc ttcaaatgaa caaagtcaac
     5401 agcggcacct aaagatttgg ggatgtcata taattgctga taagtaggaa gcatcgaaac
     5461 aacatggtct cctgcttcca ctaacgcgta tagagctaaa agattagcac cagtcgctcc
     5521 attcgtttgt aagatgtttt ccggatcgac ggtttgataa agagaagcga cttcttgttt
     5581 gaaaacatct gatccttcga tccagccata gtccaatggt tcgtttttgc gtttttcgaa
     5641 aaatttactt acgctagtcc catctaagcc aacgagttcg tctaatgtca atgcttcgat
     5701 cgagctttgt gcaatatcat ataccgcttt cttttcccat ttatttagcc attcttctac
     5761 accgaaattt gcgattttca tgtttctttc ccccttatat cttgatccag cctacagcaa
     5821 gcaacccgat tgaaagcagt gcggccacac aaatcagccc aatcattact ttttcttttc
     5881 ccgtaatttg atgtttggtt tcacgacaag cgatccagta gaagcaaaaa ccaggaagat
     5941 aggcaatact acataaaagg acataagaaa atcctgctaa aatgatgccc atcaattcaa
     6001 aaactacagc aatcccaccg atcactactt gttttttgat tccttctttt aaagaaaact
     6061 ggacttgata gatcccgaca agtagataac aaatcaaaat tgccgctgta cataaagaat
     6121 aggcaaattg ataggcataa tcagtaacta agaaagtcaa taagaataga ttagtcaaga
     6181 ttgcagtaac aactaacgaa taagttgggg catttttttt attcgttttt ccccaacctt
     6241 tcggcaacag accgtctcga gccatcaaca tcgttgtttc tgctgggagc atcgtccaag
     6301 acaaccaaga accaatgatc gaaataatca agccgatatt gatcagcgct gctccccaat
     6361 ttcccacgat tccttttaaa atatttgcca tagcaggttg tgaaatagtt gctaactctt
     6421 cttgagataa gacgccgtat ggcaagatcg aagcaaggat atagataaac aataaacaaa
     6481 gcagaccaat gatcgatgct tgctgggctt ctgaacgttt cttcgcgcgg ttggctaaaa
     6541 cacttgcgcc ttcgatccct acaaagaccc acatcataac catcaaacaa cctttaatct
     6601 gcaaccagat cgttccttgc tgccctgttc cattcactag attatcagat acgttacccc
     6661 aaaaatcagc agtgaatata ttcactttaa atgcgataaa tacaaatatt aaaaatagga
     6721 ataatggcac taatttacag atcgtcacga ttgtattgat gacgctcgct ccttcaactc
     6781 cattgtttac taataaagtc agaccccaaa taaaaatact tgcaaataaa atagaaggaa
     6841 cattttgtcc acctttgaat atcgggaaaa attctcccat ggcgctcatc agcatcgttg
     6901 caaaagcaac atttcccagc cacgcagaca accagtaacc ccaaccactg atgaagccac
     6961 ctaatttacc aaatgaagct tccgcgtaac cgaaaatacc accatctaga tctggacgct
     7021 tttctcctaa atgattcagc gataatacca aagctaaaat accaatccca acgattatcc
     7081 atgaaaggat cgctggccct ggagctgcag aactagccag atcacttgtg atcccaaaca
     7141 caccgcttcc gattgacgaa ctgacaacca gagcaaccag tccccatttg ctaatacccg
     7201 tcgatttctt ttccatttcc atcaccctca cttataaaat tgaacaaatc acttgcaaaa
     7261 gattcccttc tattttgcaa ctgctcttgc ttaacaaaaa gcaactttat tcatattatt
     7321 ggatattatg aactttttac acaagtattt caagtataaa atgaataaaa attaatttta
     7381 ttgcaaaaaa acagctatgc tatccaaaag aaaaggtgtt tcttttgtta gccatagctg
     7441 ttttgattca tttaatatcg cttaaacgta ttgtaaaact tttgtttctt gatatgcgtg
     7501 gtcgatcaaa ccaccaccca gacattccat tccatcataa aatacaactg cttgtccagg
     7561 agtgattgca cgtacaggtt cgtcgaatac gacttctgca cgattatcat ccaataagcg
     7621 aactgtcaca ggaacgtctt gctgacgata acggaatttc gctgtacact tgaattcttt
     7681 tggcattggt tcattcgtcg taaagtggat ttcacttgca tccaagcttg tggcatacaa
     7741 tgcaggatga tggaaccctt gccccacata taatgtgttt gtcgctagat cttttcctac
     7801 aacaaaccag ggttcttgcg aatctcctcc gccaccgatc cctagtcctt gacgttgacc
     7861 aatcgtataa tacatcaagc cagcatgttg tcctttgact tcaccatcaa gagtgaccat
     7921 atttcctttt tttgctggca gatagttgct caaaaattgt ttgaagttct tttcaccaat
     7981 aaagcagatt cccgttgaat cttttttctt agcagtcgca aggcctgcgc gttcagcaat
     8041 tgcccgtact tctgattttt ccatgccgcc tagagggaac atcgtttttg aaagctgttc
     8101 ttgtgataat tggctaagga agtaagtttg atctttatta ttgtctactc cacgaagcat
     8161 gtggaccacg ccgttttcat cgcgagtgac ttgcgcataa tgtccagtag ctacataatc
     8221 ggcgccaaga tccattgcat aatccaagaa tgctttgaat ttgatttctt tgttgcacat
     8281 cacgtctggg ttaggtgtac gtcctgcgcg gtattcggct aggaaatatt caaatacacg
     8341 atcccaatat tctttttcaa aattcacaga gtaataagga atcccgattt gagcagctac
     8401 tttcgctaca tccttataat cttccgtggc cgtgcataca ccgttttcgt ccgtgtcatc
     8461 ccaatttttc atgaatattc cgatcacgtc gtatccttgt tcctttaaca aaagtgctgt
     8521 tacagatgag tcgacaccgc cgctcatccc tacgacaacg cgtgttttgc tgttgtctgt
     8581 catgatatca ccatcatttc aattagattc tgaaacatct acgagttgaa ggtcgcaact
     8641 tttcagtatt ttacattata cgtcatattt ctgaaaattt catcccttaa ttatcaagtc
     8701 gtaaaaatac tgttctactg gacctattca gtacacaaac atgatagtca accaaaaaat
     8761 cactcatctt ttgagcattc gatataaaaa attggcatac tcataaaaag ggccagcctt
     8821 tcggcaataa ggaataattt tataaattgt gaaaaactat ttttcaaaat tgcttcttat
     8881 cgcttaaagc tgcacgtctc atttacaacc ttttcttttt agatgttatg agttgctcag
     8941 ataagtgatt ttgtttactc taagaaaaaa gggaggcaaa agatacatga attactttat
     9001 cagtgatatg cactttttcc atgaacgctt attaggaaaa aacgactttg ctccgcggct
     9061 ctttgcaaat gtggatgaaa tgaaccaaca gttgatcact agctggaatg cagtaataaa
     9121 agaaaccgac catgtttatc atctaggcga ccttgctatg catccgcaat atgaaaaagc
     9181 aaatgcagaa attttggaac tggtcactca actgcaagga acaatccact tgatcaaagg
     9241 gaaccatgac agtcgcgctt ttttccgtta tttagaaaaa aatgatccta ggcttactga
     9301 cggaagtccc aaattttatt tttatgatgt aggtgccatc gttaaattcg accatcaaca
     9361 atattacttg actcattatc cgatgttgct cgggcctaac gacactatcc gcaatcttca
     9421 tggacatatc catcattaca gcgtacctat cgagaacgat gtcaatgtag gcgtagacgc
     9481 accggaaaga gaactcttaa aggaaaaact accatttggc actccgttat ctgagcaaca
     9541 aatcaaagaa atctatgaag caaagaggaa gtacgatagg tcgtgaaaaa actgccctat
     9601 atcaagtatt aaacaaataa agataattac tcatattttt catttgagta ggcttattgc
     9661 cacaggaaca ttaggatcag aaatggagtt gtaacaagac ttctgtcaca actccattcc
     9721 atactattcg tctttttgct catggtgttc ttttaccagt tttttctgta attctttatc
     9781 ataatttcgg gcagctgacg ttaaaaataa aacgattccg cataataaaa tcccgattcc
     9841 ggaaaacaag aacatttttt ctacccctaa acgatcagct aatggtcctg caaataataa
     9901 tccaattgga cctgccaggt tcatcaaaga gttgaagttc cctaagacac gacctaaaac
     9961 attcgattca taactctgct ggatcattgc catcagcagt gtattgaaat atggcgttgc
    10021 acaacctgct cctgcattca agataagaaa gtacaagaac ccttgactat cgtttggaac
    10081 caatccgctt gcaccgatcg tcaggcccat aatgatgtag gctataataa taggtttcat
    10141 tcggtctttc catgttccta taaaactgat cagtgcaccg cctaagagca ttccgactgc
    10201 gtagactact tccactgctc ccgcctgtcc aacggaacca ccaaagtaat ctagcgtcat
    10261 caatggatac agactgattg ctggcatgaa caacagcatc acaaatgcac cattgatcgt
    10321 tatgtaccat aaccctttat tatccatcaa ttgctgcagc ccaaattttg catctttaaa
    10381 aatagtaagc ggaacttcca atatttcagg agaaactttt gggatcttca caaaaatcaa
    10441 taagccgaca ccaaaaactg cccccaatac atctaataaa ataaggtaat tgacaggaac
    10501 gactgaaaac aaagccgcac ctagagctgg cgcaatgatg aaattcgctg attggaccat
    10561 tcctaactgt ccattcgtcc ttgttatgtg agaagatgga acgattgtcg gcataatcga
    10621 ctggatcgtt ggcatttgga atgtttgtgc gaccgaacgc ataaacaaag acacaaaaac
    10681 tagccaaatc gggaaggatt ctgaaatcgt tccgactact gctaaaataa gcgcgaaaat
    10741 cgctacaata atatccgtga caatcaaaag agctttttta tcccagcgat ccactagcgg
    10801 tcctacaaat gggcttagta aaaccatggg aatcattcct agtaaagtag caaaactcaa
    10861 aattgtcgcc gaaccggttt ctcttgtcaa ataccagatg atcgcatatt ggacgaccat
    10921 actagtgatt cctgacaaaa actgtcccga taaaaagaac aaataatttc tcttccaatt
    10981 cgttaaaacg accgactgtt cattttccat aaacatccct cttttctttt tcattttgta
    11041 tagcgtttgc acaacaatca ttatacggga ttcttttttc aaaaaatacc tttttcccta
    11101 aataacaatc gtttcaattt aaatttcttt acttagaaac aataaatcag caaaatatta
    11161 aaaataacaa catgtgttaa atttaaaaat aaaaaagaca actaatttgc gtcgtcctta
    11221 caaagttagt catctaacaa taggccgttt caaaactagt tgtcttttta tatccacaga
    11281 tcattcgact ttttcgaata acccacggct aatcatccca tccatcagaa aataaaattt
    11341 atcttggctc attttctgtt ttggatcttt gaaaatattg actgctttca atccatttgc
    11401 tgtagtgatc gacattttca atgtttgaat atcttttgat acagtgattt ttaatttgaa
    11461 tccttctttg ctttgcggcg tggcatctaa tggtcggatc aattgataat tgcctccgtt
    11521 tgtttctgta aatccattat cgcgcaatgt atatcttttt gcatcaggat gcaaacgata
    11581 gctaattggt gcgcccagta ccgttgctgt tgtttcaaat gccatgattt tcacctcgat
    11641 aaaattagtt tctctttatt ataaaagttt atcctgattt ttactaggtt tttcagttaa
    11701 gttccctaaa aaatgaaggc gttctctcag acatctgttc atataagaat gacttcacta
    11761 gttatttttt gacagcacga actaattgat caaggaaata ctggatgtcg tcttcggtat
    11821 ttcccaaacc aaagctgata cggatggatt cttttagtat cggtgtatct tctccataca
    11881 ttgcttctaa tacgtgtgaa ggctcgatat ttcctgctgt acaagctgaa ccagtagaaa
    11941 tagcgacccc attaagatca agcttcatca gtagcaaatc atttgcttcg ccaattaagc
    12001 gaagattcaa cacatgaggg agtttattcg ttaaatcacc atttacttga taagggattt
    12061 cgtttgcttc taatgtatca agaatcaatt gctggaatcc tttatatttg ttgttacgtg
    12121 cttcacgttc ttcaggtgac agcagttcaa ctgcttttgc cataccccag atccctgcta
    12181 aattttctgt acctgcacgc cgcttttctt cctgctcccc gcctaaaagc aatgcaggga
    12241 tatttactcc gtctcgttta tataagaaac cgacgccttt tggcccattg attttatgag
    12301 cagagatact taataaatcg attcctaatt cttctggatg gatcgtttgg tttccgtacg
    12361 cttgtaccgc atctgtatgg aaataagctg gatgatccgc taaaagttca ccgatttctt
    12421 tgattggcat caaatttccg atttcattgt tcccgtacat cacagagacc aagatcgtat
    12481 cttctcgtaa cgcttttttg acctcttcga tcgacagatt ccctttttca tctacaggca
    12541 gatatgtaac gtcaaacccc tttgtctcta aatatttcat ggtattaaga acagcaggat
    12601 gttcgatagc tgtagtgatt agatgtctgc cttctttttg acgcgagaac gctgtttcta
    12661 agatagctgt attatcccct tctgttcccc cactgttaaa gatgatctcg tgaggttttg
    12721 cttgcagact gtctgcaatg atttgtcttg ctgtttccaa tttttcatgc gcgtggcgac
    12781 caaatccatg tatgcttgaa ggatttccaa acgtgtcttg catgattgcc gtcatcgctt
    12841 caattacttg tggatgcatg ggggtagttg ccgcatgatc cagataaata gttttcactt
    12901 cattcatccc ttccaaatta ttgctaggca cattctagca taaaatagcg aacaaaccaa
    12961 agaagagctc atttttgtct agaggacgtt tcatgggcat agaaaaaagg agctgtgaca
    13021 aaagtcttgt cgcagctcct tgaagctgct cacttctgtc acaacttctt tccctctttt
    13081 ttttgtttat tcgaattctt tttcttccag acggaataac ggactcatcg gtgtattttc
    13141 atggatgcgt ttgaccgctt cacccattaa ttctgaacat gtaacgattg ttaagttttc
    13201 tggatgacga ttttcttctg tgaaaacaga atcagtgata caaatatctt tgattggtgc
    13261 attgtctaaa atacttttcg catgatcgga caataatcca tgtgacgcac aggcatatac
    13321 ttcttttgcg ccgttttctt ttaatacatt tgctgctcgt gcaagcgttg ctcctgtgtt
    13381 caagatatca tctaccatga tacatgtctt tccttgaaca tcaccgatca cataaccacc
    13441 ctcagttgaa gcatcatctg catgatctac gatggctaat gtgctgttca aatattctga
    13501 aagactacgt gcacgctgaa caccgctgtt ttttggcgaa acaactacga tgtcatctcc
    13561 cgtcagacct aattgacggt aataatgagc aaacaacggc atcgtaaata aattatctac
    13621 aggaatatca aagaatcctt gtacttgaac cgtgtgcaga tctaaagtca gtactcgagt
    13681 tgcccctgct tcttcgatca agttagcgat caatttcgca gtgatcggtt catgaggttt
    13741 cgccgtgcgg tcttgcctag catacccata gtaaggcaat acgacattga tcgttttcgc
    13801 acttgctcgc ttcattgcat cgatcatgat cagtagttcc atatagtaat cattgacagg
    13861 tgcattcgtt gattgaacga tatacacatg atcccctcga atactttctt cgatattgat
    13921 ggaaatctcg ccatcactaa attgcttcac gacgctttta cctaattctg ttccgaacac
    13981 tttcgcgatt ttttcagcta atggacggtt gccattcaaa ctaaaaatct tcaacgtgtc
    14041 atcctgatac ttattactca tgtagtcctc cccaaaactt ctctattctt cgatagttta
    14101 acatattttt ccaagatttt ctgttaattt cagcaaattc ttaaggaagt gaaactgttc
    14161 cgttactcca actggcagga atgactttat gataatcgcc ccagttgtcg tgtactttgt
    14221 aataacgttc tcctgtttca gtttcaaaat aagcgtacgc tgtcacccaa tgattgccat
    14281 atgtactgcc aagtactttc aaaataccaa tcatcacagg tttgccttca cgtatacgtt
    14341 ttgtagctcg ctgccatgaa cctagaagag ttgctcgtgc acgctcatga ttgccattct
    14401 tctttaaaaa actagaaatc cctgtactaa cctgaaaagg aatcgtagga agtcctagtg
    14461 gttggatctg gctacgcaat gccttcgtca aaaccaacga atcagccgta tttttcttgc
    14521 gaatctcatt tggaagcatc caccccttac gatagtcttg ataataggca aggagaactg
    14581 ctgccgcgta agtaccacaa agatagcctg agggggtagc ccatttctta tacctcaaaa
    14641 aacgttcttc tggcaatccc acccagcaat ttgcgagttc ctttcctgac cttttttctt
    14701 cgatcaaaac gggaatatct tcttttctgt tgatccatct agataactcg attggctctt
    14761 cattgatcag cttccatttt ttacaagaaa gaccctcttg ataagtatat tttgctggag
    14821 aatattctac cggatgtcct gattgatcga taatcacata actttgatct tcaaaaacca
    14881 gagctaaaaa aagcaattta ctttttcttg actgcagctg ctgagtgctg gctaattttt
    14941 taattttttt atctactttg aaatataaag gtttatccac tacttgattc agttgggatc
    15001 gcctcctttt tttcattata agtgaaggat tgaaaaaaac aaatcagttt gattgttcga
    15061 attttcaatt ttttatgttc tatttgttaa ttccttcatt ttgtaagata atgggcacac
    15121 gaaacaaaaa aggagcgatc gatgaatgaa caaagaacga ttgaaacaag atttctatga
    15181 agcagtcaat gaagaatggc aaaaaacagc aaaaatccct gcagataaac cagctacagg
    15241 cggtttccaa gatttagttg acgggatcga ccaacttttg atgggagaaa cagacgatct
    15301 gcttgcccat ccagaaaaag tgtcttcaga aaaaatgaaa catttccttg catattatca
    15361 actggcaaac gattatgacc gaagaaatga gttgcatgct caaccgcttc aacctataat
    15421 cgaaaaagtt gaatcattgc agtctttcga cgaattgaat aagcaatttc cagaatggct
    15481 gttggataca ttaccattgc catttaatct ggatgtagat gcagatatga agaatgcgca
    15541 aacgaacgcc ttctttgctt atccgccttc tttattcctt ccagataaga cgtattatgc
    15601 atcagaccat cccaacggtg cacaactaat aggcgttttc tttgatatgg ctgttcagtt
    15661 attagagctt gccggcaaag aaaaaagtca ggcagaagca atcacggaac aagcagtgca
    15721 atttgataaa ttgattgctc ctcatgtaaa aagtgcagaa gaaaacgcag attacagcaa
    15781 aatgtataat ccgcaatctt ttgatacatt tattaaatac acagataaac tggacttgaa
    15841 aaaacttgtc acgggtttga ttgggacaac tccagataaa gtgatcgtaa ctgatccagt
    15901 gtacttcgat catttgaatg acatcctgac agaagctcat tttccgttat tcaaaagctg
    15961 gatgatcatt aaaacagtac gttctcttag tggttatcta tcagaagaat tccgccaagt
    16021 cagcggaatc tattctcgcg tattgtctgg aacagacgaa gcaatgcctc agaaaaaagc
    16081 agcgtattac cttgcctctg gacaattcga tcaagtagtt ggcgattact acggaaaaaa
    16141 atattttggc gaagctgcta aaaaagacgt agaacaaatg gtgaaaaaaa tgatcgccgt
    16201 ttataaaaaa cgtctagaag aaaatgactg gcttggggat gcaacaaaag aaaaagccgt
    16261 cataaaatta aataacttag gtatccaagt aggctacccc gataagatcc cagcattatt
    16321 cgaccagttc aaaacagtac ctgcagatca gggtggtact ttgctttcaa atactcttgt
    16381 tttcagcaaa ctcacattaa aagatcgttt cagcaaatgg aacaaaccag tggatcgttc
    16441 agaatgggaa atgagtgctg acacggtcaa tgcttattat catccatttc ggaatgtgat
    16501 cgtctttccg gcagcgatcc ttcaagcacc attttacagt ctagaacaat caagctctgc
    16561 taattatggt ggaatcggag ctgttatcgc tcatgagatt tcccatgcat ttgataataa
    16621 cggcgcttta tttgacgaat atggcaactt gaacaactgg tggacagaag aagatcttac
    16681 acaatttcaa aacaaagcac aagcaatgat cgaagaattc gatggtctgc cttttgctga
    16741 cggaaaagta aacggaaaat taaccgtttc ggaaaatatt gctgatgcag gcggtctaag
    16801 ctgtgcattg gaagcagcaa aaacggaatc agatctttct atcgaggaat tctttgtcaa
    16861 ttgggcaacg atttggcgta caaaagcaaa aaaagaatac caacaacttt tactgcaaat
    16921 cgatgtccat gcccctgcta aactccgagc aaacgtgcaa ccaaaaaacc ttgacgaatt
    16981 ctatgaaaca tttggtatca cggaacaaga cgctatgtat ctagcgccag aaaaaagagt
    17041 gcgaatctgg taagaggttg tgccagaagt ggtcagcttc aagaaataag aaggaatttg
    17101 ggaaaatcgc ttctcaaatt tttgtgacat ttcggcttat ttttcgaaga agttacttct
    17161 ggaataccat gtattagagg ttgtgaaaaa gctgcttagt ttcaagtagt aagaaaaatt
    17221 ttgtgaaaat ggctttccac atttttgcat aaatttgact tactaccgag aaactggctt
    17281 ttgaacaccg tttatcgaga ggttgtgaaa tcagcgtcct gacctgagta ttagagaaaa
    17341 aaacggaaaa atagttcctc atattttgcc gtttgttgag ctaataccga gggtcagctg
    17401 attgaacacc gtttagtgga gagattgtga aaaagctgtc ctgcatcaag taataagaac
    17461 agccaatcaa aagcagcaag gagaacctca tctataaaaa gatagaagga agtgagacat
    17521 ctattggtct catttccttc tatttttact ttcctcagtc aattgtttta catcataaaa
    17581 ggagaaattc cacttatttt tttcgctgtt tcatgacata aacaactaca ccgattaaca
    17641 aaattcctcc agctaatgct agcaacgggt tattaaattc tcccgttttt gggagtcctt
    17701 gagtgccatt tttttcactt tcttttgctg tcctatccgg atgagaaggt tttccatttg
    17761 gttttccatt tggtgattca tttcctggat tttctctttc tggtttgtca tttcccgggg
    17821 gcacatcggc agtttctcgc acagtgatcg ctttttgctg ggtaacagat tctgtatgag
    17881 cagaccattt ttccccatca aatatttccg aacgataagt gacttctagc gtatattctc
    17941 cttttgaagg tgctgaaaaa atagcggtat gattagaaaa ttgagcactt gactgtgttt
    18001 caacgatttg gatcttttct gggaaataac gcatatcttc aaagacaggc gttccttgat
    18061 ttggtgtgaa agttgacaca aaaactgtaa aaggcttcag ttcaatgata tttccttctg
    18121 cattctccgc cacaccattt gcttcttgta taataatcgg attattttgt tcatttggtt
    18181 ttgtctgatt tggttcttgt acgattgcat actctggata ttccgaagac ggtgaggttt
    18241 ctccgtcaaa aatagcacct acagataatg gaagaccatc cactctttcc ttttctgttt
    18301 gacgattccc cggtttaatc tgcatcagtc catgaacatg gatacttcca ttttcatagc
    18361 gcgtaacagg ctgctgacct tctttcgaac atgtatttag agactcgatc caatcttttg
    18421 atatggtatg tccaagagta ttttctgatt gtttctctcg ttcattccaa tagtagttca
    18481 acgagtggta gatttgatct tcgttttgat tcaatgggcg gatctgctct ctcatctcaa
    18541 gattctctgt tcggaaagat aagataccag aagcatggta gtctgtgttt cctgctgaag
    18601 aggtataaag agccacatta tatgaaccgt tattaaaact tgtactgcta ttgacgataa
    18661 tatctgttcc gctattggaa tcgattcctt tcgcaagatt ttcgaaagac aaactattga
    18721 tcaattcatg agggcccgtt aaagaagaac cgcccatttt gaatccatta ccgttacctt
    18781 ctccctcaat tcctggtacc cagccgtttc gataagcaac tgagtttttg atgattactt
    18841 ttccgatcga acctgtttca tttttagcaa aaaggtccca accgtcatct gcattatgat
    18901 acgcgataca accgtcaaat acatttcctt ctcctattgt cagtttggcc gcaaatccat
    18961 cggcatcttc aaatcctgga tcggcatttt caaaagatgt acagttcttg actaagttat
    19021 gcgcgggcca tgcttcgaaa ggatcatttg agctaccgct gatttggatt cctgtatttc
    19081 cattccgata agcatgaatc tcttcgatca aattatgatt tccagaaatc tgtaatcctt
    19141 tttgcatagc tgcactattt gtaatgtcaa accctcgtaa accccagtag tgactgaaca
    19201 gtgtcatccc atttccagtt cctttaaaat caagtacagg acgcttgttt tctggatttt
    19261 tctctgcaat caactgaatc gggttttctc ttgtcccgtt aacgcctttt ggaatcgtca
    19321 atcctctttc gaaggaataa gttccaggcg ccatgacgat tgtctgccca gcatatgcgt
    19381 atctcaatgc ttgtgtcaga gataatggat tttgtctgct tccgtttcct gcatctgacc
    19441 cttctggtgt tacataaact gtcgaatatt taggtttacg gtagtccact gtatgaagaa
    19501 tctcttttgt ttcataacta gtcatctcta cgtattcttc tggcggatag tttttatctg
    19561 gcgtaaaact gaaagtaaat tcgttcgttc cttccatcag ttttgtctga taatcaaatt
    19621 cccgattcgc agtgatagcc aagttttttg cgttcttaag cacctctcct gttgctttat
    19681 ttttaattgt caataatccg tcagcatttg ctctaaagga catagtatga tcttggtttc
    19741 ctgaatgatt actagaggtc acagtgtaaa tcggatcaat caagcgagta ggtctttctt
    19801 gcccaggagg atctgtcgca ggatctgagt aagcaacttc gattccttct accttgatcg
    19861 tcatattcct tgctgcagca aatcctgcat aaataaccga ttcatctgaa gcgtataatt
    19921 tttcccagtc atacatgatg tcagaagcca tttcttctcc tgtttcagga tcgtaataat
    19981 atgcctctaa accagtattc gtttttttca tctctacgtc cagtttagta atcgagttcg
    20041 tggccggaaa cagattccca tgaccgtttc cgaatatatt ataagaacct gtttcttttt
    20101 ccaagaaccc tgctgaagtc tctaaaggtg ttgtttccac tgagacactc ccaggagctg
    20161 gcgcagcttg cggatcttca gatgatattc ctgtgattgc ccgtgtcccc aatccaagtc
    20221 gcatcgtata tttgctgccg ctcgtgttga ccacttcttg tctatccgag tcccagacat
    20281 attcgatccg actgcctagt atggcaaatg aatttgaata aaatgcctgc ccaaacaaat
    20341 gattttttgg tactgcgtct cttaccatta aagcaaatcc ttcttgggca ttcgtatagg
    20401 tccaagattc tatttcgatc gtcgcccgca tcctaaagtt gatgtctttg gggattgctt
    20461 gataataata ggtcattcca tctgatccgc ttgactggaa ttttccgccg ttattcgtgg
    20521 aagagagccg cacgccgtct tctaatggtt caatggcata cctactagca cttgtgcttt
    20581 ctccgaaaac aacccctttc cactcttcat ttgcttcttc agattgcttt tttgtctttt
    20641 cattttctga ttctttcatc ataggatcat ttccttcttc cgtatccata tcttcactag
    20701 ttcttggtat ttcctccatt gttgacatcc cttcaatgtt cacgtgtgca ttttcttcgt
    20761 tcacagactg ttgttcgtta gcagcaactt caacgacaga aattaaaacc ggggtactga
    20821 gcataaggag attcatcatt agcgcactgt attttatacg tttttttaac aagtgtattc
    20881 ctcccgtaac aaattagaaa gcgtttactt aaagtattac ctaatttatt tttactgtca
    20941 ataaaaaaca aaattataat aagtgtattt tataaaaaga aaaaatataa cttaagttgt
    21001 tgataataaa gagatttatt aacgtaaaaa gaataagttt ttttaaaata acgtataaaa
    21061 aagagcataa aacaaagtcg tttgttttat gctcttcttt tattattttg tgctttttat
    21121 tttatcaaat cactttgttt ttttataaaa tttctgcgcc tagtgtggac tcaaaatgtc
    21181 tcaatgccca ttcatgtcca acgggatcga aacttgccac ggaatctttg aaaatatgga
    21241 gtttgtatcc tagattatac gcatcgactg ctgtatgcaa cacacagata tctgtacata
    21301 cgccggtcaa ataaatatct gtgatctggc gttctcgcaa acggatgtct agatctgttc
    21361 cactaaaagc ggaataatgc cgtttgtcta tccaataaac attttcctct tgctcatagt
    21421 cttggtataa actttttaaa gagccgtaca attcccgtcc acccgttcct atcacattat
    21481 gcggaggaaa taagcggttc tccggatgaa aggaatcttt tggatcatgc gcatcaatgg
    21541 caaaaacgac aaaatccttt tgatcaataa acttctttgt atgagcagtc agcttttttt
    21601 caattacttg tcctgctgtc ccagtagtca gctttccatc ctctgcaaca aaatcatatg
    21661 tgtagtcaat cgagatcaat gcgttcatct tagtcctcct tatacgagat gtttgacaaa
    21721 ttcgatcacc atttctgctg atcgtttgcc tgcgtcttcg ataaattcgt caaagctttg
    21781 tgtcgccgag tgatctgctg tgtcgctcat tgcacgtacg atcaaaaatg ggatattgaa
    21841 ctgacgagct gtttgtccaa cagcggctcc ttccatttcg caagctaatg cttcagggaa
    21901 attcgttaag atttctttga ttttatctgg cgagtcgaca aatgtatcac ctgtaacgat
    21961 caatccttct tttgcgttca aattcgttgc ttttgctgct ttaaccattt cactgcgcaa
    22021 atatgtgctt gcttcataat atagaggcat tcctggtaat tgtcctgggt tgtagccaaa
    22081 tcctgttgca tctgcatcaa aataagctac tttgtctgat ataacgatgt cacctacttg
    22141 taagccttca ccgattccgc cagctgaacc tgtattgatc accatgttca cgccgtattg
    22201 ttggatcaac agacttgtgg taatagatgc taagactttt cctataccgg aacgtacgac
    22261 gatcacttcg tggttaccta atgaacctga aataaataaa gcgcctgcgc gttcccatga
    22321 taatggttcg cttaggttct ctctcaaaat ttttacttct tcttccattg cgccgataat
    22381 accgattttc atctttttaa ttccttcttt ctatataaat gcgattgcta aaaaaaccac
    22441 acataacatt aggataacaa taataagaga tttcatcaaa aaagagttcc atttggtcgt
    22501 cttttcccgt tcgctgatcc ttgttttcgt gattggttta ttctttttgc tttctttacg
    22561 ataaaagctg gcaatctttt tttcttcttg ctgataagct gtttctgctt ttcgctgttt
    22621 ttttaatgac tcgcttgctt gtgcttgttg tcgcttgcga agttcgcttc gcgtaataag
    22681 cggtcctttg gccataagcc gatccctcta ctttcctttg gtcaatagtt cccagtattg
    22741 aatcgcataa atcgtctttg catcacaaat caactgatct ttcatcgctt gttgcgcctc
    22801 ttcaagagtt agatgataca actccagtac ttcgtcttca tcttgtgcta aaggattctc
    22861 gaccttctct accccttgtg catgataaat atgaaggact tcatttgcaa aacctggtga
    22921 aagatacatc gaagtaagat ggctcagcga cttcgcacga tagccagttt cttcttctaa
    22981 ttctctagct gctgtcattt cgggattttg tccttctcct ggatcgattt ttccagctgg
    23041 aatctccaaa atcacttttt ctaaaggttt tcgaaattgt ttgacaagaa gcagacgatc
    23101 ttgttcgtca aaagcaatga tcccgacacc gccaggatga aataccagtt ctctcttcga
    23161 agttcctcca tctggcaaac gaacttcgtc tacagcaaca tcaataattt ttccgctata
    23221 gatttctttg cgactgattg ttttttcttc aaattgctca ttgttcagca tatcttctcc
    23281 tgctttcttt gtaatcataa ctgctttttt ttcatttttc aatttttctc aaaaactcct
    23341 tattagttta ccatagataa accttagatt ttctctaaat atagaaaatc cttctttagt
    23401 ccgatactct ttctagtagt ccgtatgcta aaataagtat gtaatcgaat aacgaaaaga
    23461 attcaatact caacgataaa tgacatggag ggtttattat gataaaacga aattggccgt
    23521 ggcttctagc attggtcttg ctatttctct ttgtccgaaa caatagtttt tcttttgttc
    23581 taggactttt attgataggt gtagttttag ttttgtgggg actctttggt tcgcgcagga
    23641 aaaagggaaa acaagaagaa attcctgcac tgactgacga acttgaaact cactatgaaa
    23701 aaagcggtat gacagcgaat gaaatttcat tttttcgaca aacaatgaat caaacaaaaa
    23761 atgagatcaa tcaattgcaa atgaatatgc agcagacagc caaacttaaa gcaatcgatc
    23821 tccgccatga tccagtcaaa gcagcgaaag ctttattcaa agaattggtg aaagaaccaa
    23881 accgactgca tgaagcaagt cagtttcttt atacgcatct gccgaatcta gttgatttga
    23941 caaataagta taatgagatc aatgaccatg agatcaaaaa caaacagacc tatgaaaaac
    24001 tagaagaaag cgcgcagatc atcgaccagc tgtcagcttt aatcgcacaa gattatcaaa
    24061 aattcgttgc tgaggatcta gatgatatcg acgtagagat atctgttgcg aaacagagct
    24121 taaagcgtga taataaatat gaaccagaac aaaaggatta actcttttgt tcataaaaga
    24181 agactcggaa cattcagatg atgtctggct gtttcgagta ctttttctaa agtagagaca
    24241 ttcatgtaag aatcgagaac agattcaaca aggaggaatt ttttatggat cataaaccga
    24301 ctgaaacaaa agatgttaca ccagttaacg atacacttga agatttattg aacaacccgt
    24361 tttcaactcc aacagatacg ctgaccactt cacaacaagc ggagattgat cagctccaag
    24421 agcaacagac agctgctcgt ttaattgaca aactaccggc ggaacgccaa gaacaagcta
    24481 aacagctagc agcaaaaatc gatgctaatg atgcacagtc tgtcatcagc tacggatcgg
    24541 ctgcccaagc aaaattaagt gaattctcac aatcgatgtt gaatcatgtg caagcacaag
    24601 atattggtcc tgtaggagat tccttaactg aactgatgta tcgtctccaa gaagccaatc
    24661 ctgacgaact gcgtgccgga gaagggaaca tcttccagcg tgtcttcggg aaggtcaaac
    24721 aatcgatcta tgaagtgaca gcaaaatatc aaaagattgg tgcacaaatt gacaagattt
    24781 cagtgaaatt agataaagaa aaagacggtc tgctaaaaga taatctgatg ttagaacagc
    24841 tttaccagaa aaacaaagac tactttgatg cactgaatat ttatatcgct gctggagaat
    24901 tgaaaatgga agaacttcaa acaacgatca ttccagaagc gatgaaaaga gcagaagaaa
    24961 ctggcgatca gatggatgtt cagattgcca atgattacac gcaattccta gatcgtctgg
    25021 ataaacgtac gcatgatctt cgcttagcta gacagatcac gatccagcaa gcaccacaaa
    25081 tccgtttgat ccaaaacaca aatcaggcct tggctgaaaa gatccaagca tctatcgcta
    25141 cagccattcc gctgtggaaa aaccaagtcg tgatcgcatt gaccttgctt cgtcaaaaag
    25201 atgcagtaac tgctcaacgc caagtctctg aaacaacaaa cgacttattg aagaaaaatt
    25261 cagaaatgct gaaaatctca gccatcgaaa cagcgaaaga aaatgaacgt ggaatcgtgg
    25321 atatcgagac ccttcaaacc actcaaaatg atttgatcga aacaatccaa gagacattgc
    25381 gtatccaaaa agaaggaaaa gaaaaacgtc gtcatgcaga agtagagctt ggacacatgg
    25441 aagaagatct gaaacaaaaa ctgttggatt taacccaata gatcaccttt cgcttgttac
    25501 taaaacaaac gcccaacaac agtttattac aactgttgat gggcgttttt cttatctttc
    25561 ttctaacttc tccattggag tctatttctc attcatcttg ctgtgtccat agccatagcc
    25621 aaaataaatg atcagtccaa taaccattac gataccgaac acgatccatg tcacagtttg
    25681 cagacgaagc atcaatacaa tacaagtcaa aatggagacg attggcaata gcggaacgaa
    25741 tggcactttg aattctccag cttttggttt gccaaacatt tttctcaact tcagtaagcc
    25801 tagactaaca agcatcaaat aggcgagcgc catgatattc gttagttccg ctaatacatt
    25861 caatgggaaa aatccggcaa agaatacagc tgccacacca gcggcataag tcgctttttt
    25921 cggtgtacga tgcttttgat cgatttctgt cataaactta ggaagtaagc catccttgct
    25981 gacagcaaac agtaaacgag caagtgaata catcatcgag atcgttaccg tcagtagcgt
    26041 taaaattgcc cctacagcga tcaccgcgcc cactgttcca tgtcctacat acctcattgc
    26101 aaaagccact gggtcattga ctcctagttc agtatacgga acgattcctg tcaagatcag
    26161 cgtcacgatg atgtaaagga cagtagcaat cagtatcgaa ccaatgattc ctcttggcac
    26221 atctttttgc gggtttttga cttcctcggc tgccattgca acggcatcaa atcccaagaa
    26281 agcaaaaaac acaagagctg caccatctag cacaccggaa aaaccaaaag gcatgaatgg
    26341 ctgccagtta tcaggtttaa cgaaaaatat tcctacaatg ataaacaacg cgatgatacc
    26401 aaatttgaca tataccatgg cattattcaa acgtaatgct ttcttggctt caagcgacac
    26461 gatgtaagtg acgaatatca ctacgagcac cgcaatcaag tcaatgtatg taccattttc
    26521 cggattgtac ccgccagtta atgcttgtgg aagttcggcc cctaaacttt tcaaaaaacc
    26581 ttgcatatag ccagaccatc cggaagcaac agaggaaacc gctagtaaaa attccccgat
    26641 caacaaccac cctgtcagcc aggcagcaaa ttcaccaaat acaacataca gataggcata
    26701 tggcccacca atcactggca ctcgcgaagc aaattctgcg aaacttagtc cagacaaaat
    26761 gacaacgatt gcagctaaga caaatgaaag tgacagtgct ggaccagcat tttgattggc
    26821 cgcaacccct gtcaccacaa atattcccgt accgatgatc gcaccaattc caagcatgat
    26881 caaatcagac gtttttagtt cttttttcat ctcactcgta tgattgagat tgatctcttt
    26941 cttacgaaac aaatccattg aagttcctcc ccattttagg ttggaaaaca gcgattaaac
    27001 tgttttcata taccctaaaa gggataccac ctaaaatgac taaaaggcaa ccaacaataa
    27061 cataaatgag ctcttttttc gtttttcttt cgccaaggat gaaaatccca cctaaagtag
    27121 agataatgat ccccatttgt gaaagtgaga agccaacagc taaaccaagt gatttgactg
    27181 ttagaagcat gcagatgttt cctaagcccc ataataatcc acagatcatg tttttccaca
    27241 caaactgatc gactttaact ttacggaaag caaagaagct tgcgcctaag atcattccga
    27301 tactttgagg taagataatt gacatcgcat ccaaattcgc ccagttgacg atgatggtat
    27361 atacaccata accaatcgta gagaagatca atgctctaaa acccttacca aaatcaagca
    27421 ttttattatc tgtatctatt tttccttcgt catcttgtcg ggcagtcaaa tacgcaccgc
    27481 ttacaagaag agctaaagca ataataccgt atacataatc tttcgtttgt gtccattcat
    27541 ggaagaaaac ggctcccgca atcgtattca aaattaattg aaaaccagta gacaatggta
    27601 gccctacaga aacacccatg tacttcattc catggaactg tccattttgt ccaacactcc
    27661 aagctaagcc ggataaaaat ccgatcaaga aaatccaagg ggtgattaca ggactaacaa
    27721 cgaaaaagac aactaaagaa aacagaaatg caccgatcgt cattcctagt gtttgttgat
    27781 tggcatcgcc accaatttta ccacttacta aaccaatact accccatgcc aacataggga
    27841 ctaatgctat taaaatttcc ataaccaatc tccttttatt tcacatgata agaaacttat
    27901 cagcgaaaac gttaacaaca caagcacttt ttttcgtttc taacgatttt ctaacgtttt
    27961 tcattataaa aatttaagat tgggaaaaat aaagtcattg ttgtcccttt tccttcagtt
    28021 gattcagccg tcaaatggat acctaatttt tcggccagat tttttgctaa ataaagtcct
    28081 aatcctgttg aatgtgtttt gctaagtcga ccatttctcc cagtaaatcc cttatcaaag
    28141 atccgtttca agtcttccgc tgggataccg atccctgaat ctttaactga aaggctgact
    28201 ccttgcgctt ccttttctat gctcacaatg atgtttccgt gatccggcgt atatttgatg
    28261 gcattactaa gcaattggtt gaagataaaa gcgatccatt tagcatcggt caaaacagta
    28321 tgatcctcac caacgatctc gtagcgaata tttttttgga taaaataatt tgcctgactg
    28381 cgtatcacag gctgaatgat tccttttagt ccatattctt ggatgaggta gtcccgcgag
    28441 aaactgtcga gtcttgcata atacaaaact tgttctacgt attcatcgat ttttgataat
    28501 tcattttcta gtaatgtata cttttgatcg tcaatatcga actcgatcga acgaactagc
    28561 aatttagaag cggaaagtgg cactttgatt tcatggaccc atgagtcaat ataatctttt
    28621 tggtcttgtt gattactgat tgctgattgc attacttctt ggtgttcacg gatcagctga
    28681 ttgatatatt cttctaccag tttttcttct tctgtcctcc caccactcaa ataattttgc
    28741 aaaggggaag ttttttgtat gtcggctaat tttccccacc atcttctctt gctcaagtaa
    28801 ccacccagca gataaaaaat cagaaagacg ccctcaatca aagctaaata agcaattgtg
    28861 ctcaaatcaa ctttgatgtt tggcgccagc cacatcacaa agatcgtcaa tgcaataaaa
    28921 aacagccatc ccaagatcaa tgtccactga tctttcaaat atttaaaaaa attcatctta
    28981 accgctcatc ctttcaggga acgatatatc cctgtcctac ttttgtttcg atatatcctt
    29041 ggatacctgc ctgttcgatt tttcggcgta accgattgat gttgactgtc aatgtattgt
    29101 catctacaaa tcgttcgtca tcccacagtg ctcgcagcaa tttttcccga cttaagatct
    29161 ttccattgtg cttcatcaaa ataaataata gacgatattc atttttgctc aaatcaatga
    29221 tctctccgtt gatttccata cttccgttgt caacattcaa cgtaatgcca ttgtggctca
    29281 tcatttcact agataattct gtgtagttgt aagaacggcg aagtaatgca ttgatttttg
    29341 caatcagtac atcgatttgg aaatgttttg tcacaaaatc atctgccccc atgttcatag
    29401 ccatgatcat atccatattc gtattcctgc tggagataaa aatgatcggt actttcgata
    29461 cttcacgtat tttttgacac caataatagc catccaaaac gggaagatta atatctagta
    29521 atacaagctg tggttcttct ctttcaaagt ctgagaacac ttgattgaaa tcggtcgttc
    29581 caaaggtttc aaattgccat ttctcaagtt cctccatgat caattgtcga atgatctctt
    29641 cgtcttcgac taccatgatt tttgccataa aaaatccctc catctttctt cttgctacta
    29701 caatatcaaa gaagcccttg tgaaacaagt tggcttacct ggaaaatgtc attttagcaa
    29761 acgttaaaaa aaactggaaa tatgcgattt aatcgcgttt gtctcttcca agcagcttaa
    29821 atttattatg ttattcttaa taattggtct attatctgtt atttttcttt cgttgttttt
    29881 gtcttttaaa ttttcgataa caccaataac cgaaaagcgt tagcactagc aatataccta
    29941 gaaggagtat aagtaatcga taaagatggt atttttttgt ctgttctatc tttgaagaga
    30001 cttcttctgt aaagggaact cgtcttcctg tcactagtaa tcggtgagtg ttcacggtgt
    30061 aaggtgtaca agtgataagt gtgactagat cctgcttttc tctaattgct aatgtatttg
    30121 tttttgttgg aaggacaaca attttctcaa cgacttcata agcgagcatc cgaccataca
    30181 cttcaagata gaatcggtca tcttgctcca tttcttcaag atccgtaaag agttttttct
    30241 cagcaatacc gctatgggcg gtaatcacgg aatgtgtact ctctcctcca gttggaaaag
    30301 aggtgccttg caggactgtc gctcctctat ctaacaaaag atcattcgtt tcatcaaata
    30361 aaggcaagct aacattgatt ttcggaatat agatggctcc gatcatatgt tgttcgtaat
    30421 attcttttcc tggattttgg acatttctaa ccgcttgctc aaaaggatct ttgacttgtc
    30481 ccattcctgg gattactgat gtatgagcaa gcgtctgatt tttcttttca tgcactgcta
    30541 attgttgctc atgtttttct tctttatcgc gttcaagctg cttttgataa ttctcgatcc
    30601 ttctttgatc caaataattg ctgagagcat ctgctaaaaa tggatatgta aaaactgcag
    30661 ctccggcaag aaacatcact gccataaata attgtaataa aagactgatt tgggtttgag
    30721 gtctattacc tattttcttt ttcattttct tcaccttctt atttaaaaaa actgcagcaa
    30781 cctttataaa accgattgct gcagcttatt tttgttgctt atacttcaga cttcatttta
    30841 gatttacggt accagctgta cgctccaatc atcaaactta ttccgattag taagaatgcc
    30901 aagagcccgt tcccaccagt agcaggaagt gacccgcgtt tcatattcgg tactctttct
    30961 ggccctggat tttctactcc tacgatctga atttcttcat tatagcttcc ataagagatg
    31021 ataaattcag taaaggctgc ctcacctgtt ggaagtacat aaccttctgg cgccatggtc
    31081 tctttcattt gataggttcc ataatctaac ccttgaacct caaagtatcc atttccatct
    31141 gcgacaaatt ctgttgcttg tccgcttgtt gcccactcaa ttctatctgc tcctgattca
    31201 taaacagcta aaggcgactc ccctttataa aatattgcgt attcagaacg gtcttcattc
    31261 cacaattcga atcttgcatc tttaagcaat tcactgcttg atgcatcata tttttcaaac
    31321 tttcttccac ctgttgtgac tttctctggc ggctctactc cttcttcata atcaaattca
    31381 tcatttcgtc cgatttcaat aaccgctgtg ttgttatgga aatcatccgc ttctagttct
    31441 gtggaaacct tcaaattata cgtgatcgtt aaatctcctc cacgtgcatc tgctaatcta
    31501 cctaaagtat ctactttggc tactccattt tcttctgtca aaatcgtcac gacaaacccg
    31561 ttgcttacta cttctactat ataatcttgt ccttttgtta aaatcgtctc gccggctcgc
    31621 acttctattt cctgatcata ataagttaga ccaactgtag gcgtatctgt gattttgtaa
    31681 tttttgataa cagcgcttcc gttttcaagg acagaatcga tgaaataagg aataggtgct
    31741 gtgatcgtgt aagaagccgt ttttcctctt tctagatcaa tataagaaat cgtttcttgt
    31801 tctccagctt cattaataat cgttacttgt ctaaggtcgc tttcctctac attcatctgt
    31861 ttatctgctt ctctgatttc gtttttcgga tacaaatgca catctgtatt gtatgtgtct
    31921 ttccatgtag aaccatccca cacgccatcc accatatcag gcatcatcac tggcatcata
    31981 acaaccattg gagacgcgat tctggaaata tgagctggcg aataagtttc taagaaaaga
    32041 tagactttat ctctagaaga aggtgcttct tccgtcactt ggacggtaga gaataccgct
    32101 tctccagctt cattcgttgt ttgtttgtca atacttgtca gtcgatattt taaaaaccaa
    32161 ctttctgtgt gccgtttttg aatccattca atcgcttcgg cagaattaag accgtcttct
    32221 cgttccggtg ttaaaggatt atctcgaatc aaatcgtaat atacttccgt tacgtcaaac
    32281 aaatcaaaat cgactcctgg aatattttct tcaccaaaat ccgtagaaac caatccgcta
    32341 ttcggtcgtt cttccggaac agatgagaaa ccttttttgt gtaatgtaat cgtcacttca
    32401 cttggttttt gtgcgacttc ttcggctttg actagttttc cgttcccgaa aatccctatt
    32461 cccgcagtaa cgagtaacag tacactcatt cccgtgacaa tcattttttt attcattttt
    32521 ttctccccgt tcttttttta ttaataaaac agcacctaac aataaaagaa ttcctagtaa
    32581 agaaatcaac gttcttgctt cattcgtttg cgggaatacg gaccattttc ctgattgacc
    32641 tggattgctt ggaccactcg gctctttcgg tttgtccgtt gtttctttta cggtctcgtt
    32701 ataaacacgt ggtgttgcgg attcataggc agagactgga actttcccgg attctaattc
    32761 agccatctcc tgtccgttaa ctactacata ttgtggttgg ccttttgcat ccacccaaaa
    32821 ttcagggatg atgacctcga ttctcttact tgcttcatcc atctcgtaac cttccacacc
    32881 ttttaattct tcaaaataat aggtgccaga aggcaagaaa cgttgtcctg tcgtaacaag
    32941 gccctcttta tccgaaatga atttgcttac atttttgtca ttcaaaggat cattgtctgc
    33001 tggtttgatc cattgatttt tcaagtcatt agcaggagcc atatctaaat aatatttccc
    33061 cccttctatc atctgatata gagcaaaaac agcaccttct aatggttttc ctttttcagt
    33121 tgttcctctt tgacgtccat acttgaagaa gtatggatct cttagataac cgacattttt
    33181 aggatagata tgaatctctt gcagttcctc ggttgattct gtcgggtgat aaattggcaa
    33241 aatagcagca attgggatag ctgtctgatc gatatcaaca tccaatccaa cttctggatc
    33301 aatcgattct tcgaaaatca aataaactgc atcccgatct tggtttttct taggtgcttt
    33361 gatacgtgca atcccgtctc ctaatccgcc aaccgtatct ttcccagttg ttaccgaagt
    33421 ccctatttgg acaagccttt cttctgtgat tagctgacgg atattgtttc tgttcgtttc
    33481 agcgatttgc tggacgaatt ctttaggagt catgttttca gcagcttttt tttcatgata
    33541 ataatcggtc atgtcgtaaa tggcaaatgt cgctccattt agtggcaccg tctgtgaaat
    33601 gatatctgct gtttcccctg cttcctcaga gatagccaag ccatcatttt catggtattc
    33661 aaattgatcg ttataatcga tatctcgaat catccgttta tgcaacacga attccacgac
    33721 atcttcccct gattcttctg ccgacatcgc atgtggaaga aggactgctg caagcggtag
    33781 taaaacaagt aattgaagca tcaaacacaa cagctttttc attaccttgc tccctccttt
    33841 ttagattgtc tgacaaacaa accataggct gctcctgcaa gcgccatgaa gaatgcagca
    33901 agcaggatat agaataatcg tccggatcct cctgtagcag gcaacggatt ttcaggatcg
    33961 ttcccgacac taagctgtaa tctgattcga tttgtctcca aaagttcata ttctaactct
    34021 tgctgtagat caggcgtctc tgcttcttcg tttggataat acgaaatctc aacttttagt
    34081 gtacccgctt cttttcctgg aactacccga tcattttcta tgtcaggttc ttctcgataa
    34141 ctaatttcta aaataaagta acctggaagt tttctatagc tgtcaggtga cttcacttcc
    34201 ttgatccgat agaccccttc caacaagtct gaagcattga atagggaaga atcgtttgga
    34261 tctggtgcca agcctccctc gatgatttca tactctcctg cactattttg tttctcaatt
    34321 gaaaattctg cgccttcaag acgtcggcta ttcatactgt caattttcaa aagttccaaa
    34381 tcgattggcg ctagttcatc ttctaaggtt acttgtagta caccatcgat gatttcatag
    34441 ccttccggca agggagcagt ttcgtcttcg atgaccgtat cttcaatgat aaacttacct
    34501 tcttcattca gtgcaaactg gaacacttga tcagatagcc gatacccatt tggtgcgaca
    34561 gattccgaga cctcatattc accaatagac agatgcagag gttggtcgta atttaaatcg
    34621 acatactttt ctactcctac ggcacgagaa tagaagtatc cgatcccagg caaacgtttc
    34681 gattcttctg gttctaacgg attaccagtg tatgctcgat acagcgggaa ggaagaatcc
    34741 cccactttcc tgatatcgaa acctgcacca tctaatgtat ggccttcatg gtctaatttt
    34801 ctaactcgga tctcccgata atcaaacgta ttgtaagcag tgaatgctac ccataaacga
    34861 tcctcttcat ctgttgtata cgtgagatat tgccaatttt cttcacctgt ttgcttgagt
    34921 tggatagtcc ctatagcatt atcgtaaagt cgcaagatcc atgtgtcatt ttcatcaggt
    34981 tctttgaaac cttctgggtt ctggctctca atgattttgt attctgcata gttggtagtt
    35041 tcttcactat ccttataaac aaatgaatct ggctctccga ttggatgaat aactttctca
    35101 ccatccacga ttacatattt cccgtcttca tctactgaat agaacgtgag tctccctttc
    35161 tcttcctcta cttcgttcac accagaaagc cctttcgcta ctggatatcc gatttccagt
    35221 ccgttaccat ctgtttcata aagttcaaac tctgcgccat tgattggcat attactgcct
    35281 tcaattagtt tattgatatt catgtggatt ggcttgaatt catttcgcat ttccagtttg
    35341 acatacaact catcatactc tgtgccttct atgttaggct cttgtacaac agaaagcttg
    35401 tgatattctc cttcataata ggaattcgga tctttacctt ccggtccgcc gactctcgaa
    35461 ccagatgtat attcatctac aagctcgtag tgacctaaca tctcatcttc gttggctgca
    35521 tattttttga tttggaattg atacgtctca tctactaact gataacgtgg tggtccagcg
    35581 atctctctga tccaaaatat gtcgctgact gctccagttt catctcctaa aatcggcatc
    35641 ttcgtttcaa agatcgctat tccgtccgtg gtagttttac ttgtttcgat tggttcggct
    35701 tccccactct ctggattttg gtcatataat gcaaattcga ctccagccaa cggctcgcca
    35761 ttttgaccct tcttgctgac ttggaaatta cggcctttat gttcgtaacg aatggaagaa
    35821 gatgggaaat acatccgtcc agtagtgata tcattctcat aatcctccag gttctgaata
    35881 taggccatat tgttcactgt gcaaaaattt ccgtcttgag ctcccgcatc aagttttact
    35941 tggtacttga tcctgaccat ttccccttca cctaaagaaa tcggagaaaa tttataagct
    36001 tggttttccc gtccgacata cgttgtcgga gtcgccacta cttctggtgg ggcttgtcca
    36061 tgacgttctt catcccatat ttctggctct tggtacttca tgccgttttc tcctggatct
    36121 agatggtaaa actgaatatc tgccgatctg ccagctccaa atggtgagac attaaaacca
    36181 gtttcatcat aaagtgtggc ttgctggatc gttctcttga aggtagaaga gatatcctcc
    36241 aaggctgtaa caatgtcatt cttgttgttc gcattgtaat atcgcggtgt tacgccatct
    36301 tcttctaaat cagcaatatt tttcaataca tttcgtccaa tagcatctag tcgttgtctc
    36361 ccgctaacgt ttccatcgat tcctaaacca atggagaaga tacttggcgg gttctcttga
    36421 tacttgtttt tcagccaatg atgataagca actgtgttga tcgcagatga cttttcttgc
    36481 gaagtaggac tgccattcgt attgttatta gaagaaccat caccaaccca gtgagtcgct
    36541 ttattatctc cttcttttac ctctccataa cgatagtgta catttacttc atcttctgga
    36601 cggttaaagt cagatgcata ggtaactgga tgagtaaacc ctgcattaga agtattccca
    36661 gaaaactcct caaaatttct gaacaaaacg tcattatctt cagcaatctt atcttccatc
    36721 acagtccagt tgctccaagc tccattagtg ctcgtacgat aacttgactg aatcggtgca
    36781 taactgaagg tcggtgtccc atctcccaca acgattagga ttttttctgg atttctattt
    36841 tctccgccat tgtctttata caatgtttca tagccatttt taagccctag tgtaagcgga
    36901 gttcctccga ttggtgtacg atttaatgct gtattctcac ttcccgtcaa acgattgata
    36961 tcatttgtca atggaaagat gtccgaactg atttgctcat ggttattgat agctgtacta
    37021 ttatggtaaa aattcaccat accgattcga atatccagac tcgggtcaga gagcagatct
    37081 ttactcattt cgtttactgc ctcaatcaac gcagcatttt tagtttgact attggtccca
    37141 gcggttaatt cactcatact cgctgactta tctagaacaa aaacgatatc gattggactg
    37201 atttcctttt tctcgccccc gatgacatct agatagacat tgtaaagggt tgttgcatct
    37261 tcaggatgta gatcagatgc tgtgctgctt ggcagaacag gttctaccca ttttttgatg
    37321 tacgccccgt tataatccaa gtaactgttt tcaaaattcc gttcatttcc ccaaagctga
    37381 acggtttgag ctggaacgtt tctatcttct tcgcctgcag ttgatccatt attagtagca
    37441 tagtcgtaat ttcgccagtt cgctcccccg tttgtataat cactatcatc gatcaagttc
    37501 tctccgtcat atggcgagcc tttgtctcct tgatagcgtt cattgctttg tgtccaattt
    37561 cctaacactt ttgtatagtc attcgttgta aacttcgggt agcgatgctg ttcgttttca
    37621 acttctccgc taggatagat atattcatag gggtcttgcg tagctgttgg cccaagacgc
    37681 tccaaaatac cgttgaataa ctggcgttga atgcgctgga gtgcttgacc gctgggtacg
    37741 attggttcgt ccagcttttc catctcattt tcttcgctac gttgaatttc agcggaatct
    37801 tctgtatcag tttcattttc ttgtaattct tggttatcta ttctttcatc aaccaccact
    37861 tgaagaggta gttacccttc gttcacatcg gggatctttt ctgtttcaaa aatcaatgtg
    37921 ccggtttctg cttcttttga ataaactttt ccgacatacc attcttgacc atcgatcgtc
    37981 tcgactttta ggtcttctcc atcttcatca taggaggata gacctgttcc acgaacgttt
    38041 tttacggtac caatcccggc ggctgccgca tcgattgcta aacgtattct accttcattg
    38101 gcactttcct ttttttcaaa agccagatgc cattcaaggg tttcttcttt ttcaatatac
    38161 ttcccttcaa tttttgcata gtcctcatct aagaatacct catcctcctt tgtttctgtt
    38221 gactcagcag ctacatccag ggtcgtcata tgatagactg actggaaata tggtccaaat
    38281 agcaaactga cagttactaa ctgcaaaagc ttcaatttta accctttcac atccttatac
    38341 tcctttcaaa aatatttgtc ttctttcaca acaatcaaca aaacaatgcc catctaatta
    38401 taatttaatt taattttaat tttaaatcaa atgatatcct ttttagttaa aaaacaccaa
    38461 ttatacaaca tttattatta aaattaaatt ataaaatttt ataacgttct catttaacaa
    38521 aacttaagtt attaagacaa atgaataaac aactacgctt tcctcgaaac aaaaaaataa
    38581 agcacaaatg cgcatttacg cactcatgct ttattcgtac aattaattca gataacggca
    38641 gcgcatagga tgccaataac acttcctaaa atagctcctc ctaaaatgtc agtaggataa
    38701 tgtaaaagta aaaaaatcct cgaataagcg atcaaacaag caaataaaaa ggctaatatt
    38761 cctgcaactg gacttaattc gaacaacgca gctactgata aaaaggctag cgctgtatgt
    38821 cctgaaggaa aagaagaagt cttcggttta cttgtgtaaa ggacaagccg acgatttttt
    38881 tcataaggtc ttttccgtct tgtcgttttt ttgataaaaa gcaaaccaac aaaaaaatag
    38941 atcaaactgc cgataagaat ggctagacca tattctctag tatcaggtat caagactaaa
    39001 acagcagcaa ggagcaacca aataaaacca ccattagaga tattactgat aaatttcaaa
    39061 aaattgattt ttcgactatc cgttttccgt tgcttggcga acttgttgat aatactatca
    39121 tcgattttag caatcaaacg caacatgtta ttcctccttt ttaagaacct tttcttgcgt
    39181 acgatggata aaaagcagga cttgaaaata aaacaagaaa ctgaaaccta ataaagcaaa
    39241 atagattggt cctgcaaacc agaatgcgac aagaaggatc aacgtgcctg ccaaatagaa
    39301 aagcgcgctt ttgaaatcat taaaaaacaa gaaaaatgca gtaatccaag aagcttcttt
    39361 ttgttccagt tgaagcaaga ttttgtaact aaagagaagc gcgcttaata gaagcaaaaa
    39421 caacgtagta tacatcaatg tatagccaat tcccccaccc caatagcgga aaatctgata
    39481 atcgatcaat agaagaagaa aataaacact tgctaaacta tcttgctttc cataaagaga
    39541 gaagttctca cgaaactttt tccagaatag tgaaccgagc tttttctctt catttttttt
    39601 gtaatgataa atcatataca gaactgttcg acttgcagtt cctaatgtga aaacaggcaa
    39661 gacgcacagg aaccatagta gctgtaaatg gataagacgt ggaatccatt caatgatttc
    39721 taagaaataa tcattggctt ttttaccaat cgatcgattc atcatccttt tgaacctcct
    39781 gtcaaatcca tcccttcaat gaaataacgt tgtgcaaaaa agaacagcaa aatcgtcggg
    39841 atcaagacaa gtgttgctcc tgccatcaga taattccatt gtgtcgttgc ttggttctga
    39901 aaaacttgca agccaatctg taacgtgtat ttttcttgat cttggatata taacagagga
    39961 cctaagaaat cattccaagc tgcgttgaag gaattgatcg caatggtaat caaggcaggt
    40021 ttcgtcaatg gaagcatcaa atgactccaa atatacaaat gattcgctcc gtcgatttca
    40081 gcagcttcga tcaattcatt attgatcgat aagtaaaatt gacgcatcag aaatatattg
    40141 aacgcattgc cgaagaacga tggaacgatc aggggcaaat aagtacctac ccagccgatc
    40201 ttggagaata atacatattg agggatcatc gttacaaacc ccgggatcat catcgtagaa
    40261 agaaccaaag caaacatcag ctttttccca ggaaaatcaa gcttcgcaaa tccataagca
    40321 ataaaagaat ttgaaaggac attaccgatc actactagca cagtgatgaa taatgtattt
    40381 cttgcatagc gccaaaaagg aaaggcggca atcgtatcca gatagttttc ccatacgatt
    40441 ttttctggga aaaaggtcgg aggataacga acgatttctt ccattggttt caatgaagta
    40501 aacaccatcc aaagcaatgg aatgatcaaa atgattccta ttactgtcat gaggacataa
    40561 cttagtattt tttttgtttg ccgattcaca ctggtctttt tgaaataatc catcatttgc
    40621 cgtcacctcc agaataatag acccacttag gtgcaagctt caaattgaca aacgtcagaa
    40681 ccaacacgat cagaaacagg atcattgaca tagccatcgc ataacccata tcaaaagcta
    40741 cgaacgcctt gttccacata tgcagattat aaaaaagcaa agaatttgca ggtccgcctg
    40801 ttccattttt cgtcatgaca taagcttctt gaaaaatttg gaaagaaccg atcgtagagg
    40861 tgatcacatc gtaaaaaata ataggagtga ttaatggcaa agtaatactt ttgaactttc
    40921 cccaaacgcc tgctccatcg atttctgctg attcatataa agatctagga acattttgta
    40981 atgtagctaa gtaaagtagc attgctcctc cagaactcca tattttcatc aaaatcaacg
    41041 caggtttcgt ccattgtgga tcaaacagcc aagctggtcc agggatatgg aaccagccca
    41101 gaaatgtgtt gatcaatcct gcagatggag aaagcagctg catccataag atgtagactg
    41161 ctactcctga taagactgcc ggtaaataga aagctgtacg gaatacactg attcctttga
    41221 ttttttgatt gagtactgtg gctaaaaaca cactgaaaat cgtcgtcagc ggtacattga
    41281 agatgacgaa ataaacggtg ttgtataacg atttccaaaa taaatcatcg tgaacgaaca
    41341 ttcttttgaa atttgctaga ccaatgaaat tcatcttgga tgtcaaatta taatcggtga
    41401 aactaccaat aactgaaaaa agcataggcc ctagcataaa taccaagaac ccgataataa
    41461 aaggcgagat aaataaatag gcccatcttg cttctttttt ctttcggata gataaacgct
    41521 tcaaattttc ttgcctcctc tgtacctaga cagtcaaaaa tggattattg attttgcttg
    41581 actaagtttt ctactgcttt ttgtgcatct gccaatcctt cttttggtga ttttgttcct
    41641 aaaagaatct ggtcaatctg ttcattcact aatgtcgtgt aatccggagc atctaaagga
    41701 actggtgtga tcaccgtatt tttaaagttt tcgtccgcca tttgatagat catttttcct
    41761 ttatccgtta ggttgtcatt attcactaaa ttctcattgg ctgtcttgct cgccatgata
    41821 tcaaaacttt tttcgccgaa tttttcttgt acttctggag aagaaagata tttgatgaat
    41881 tcataagagg cctcaggatc ttttgctccg tatggtactt ccaagacgaa tccgccaccc
    41941 cacgaccaat ggcctgaacc ttcttctttt tctgggagct gcatcacgcc aaaatcaaaa
    42001 tcatccggtg cattttccat caaactagag taataattga tattttgggc acgcatggct
    42061 actaatccgg aaataaatgg atcagataca ccagacccaa attcggcttc taatttattg
    42121 atcgtatttt tcccataata atcttgccag tcttggatcc actccaaggc ttccacttta
    42181 tttttagtat caatcttgac tttttcatct ttgtcaaacc aactagtccc gttatctgcg
    42241 tttagcgccc atacatcagc ccctaaattc cataatggat aaaaaccgat gcgtgtaaat
    42301 tcttttcctt cttttttatc tagtttacgt gctgtttctt ctaattcatc ccaagttgtc
    42361 ggtagatctt gttcactgat tccagcttct ttaaataact ttttattata aaaaatgact
    42421 tgtgtatctg tattgaatgg gatcgcataa ggatcacctt catattctac tgtatcccaa
    42481 agctgcggat aaaaatcctt agaagtgtct ttttctacat atttggagag attagttgct
    42541 tgctgtgctt ctgctctttg ggcaacggaa tttatgtcct gtacaataac atcgggtgca
    42601 tttccagctg ttattgcaga taaagattta gtccagatgt caccccatgg ctgatactta
    42661 taatttacat ggatctcgtt ttgtgattga ttgaaatcct caatgatttc ttcgatagct
    42721 tcttttcgtg caccggatcc ccaaaaggac cagaaatcaa tattttttct tccatcactt
    42781 gttttttcag aagaatttgc tgcacttgaa ctggcatcgc ttgcattact tgatccgcat
    42841 cctcctaata aaaacaatgc tgaacttgcc agcaaccctg taaacaataa ttttttcata
    42901 ttttacctcc aaattttaat gtaaccgatg ccggttttaa tataacgata tcattttgtt
    42961 ctgaaaataa caatttataa ggtatgattc taaaaaaatt attaatgata ccaatacttt
    43021 atataattcg cgagcgcttt ctttgaattt tttaatcttt cgtagcagaa tgagaatgta
    43081 ttaaaaatag attaggagga attttgatgt ttagacacca gaaagaattg cagtttgaag
    43141 caaaaccaga tcgtccgaat ccattaatcg cgaaatatct gcaggagctg atcggcggcc
    43201 aatatggcga gatgagtgta gctatgcagt acctgttcca aggctggagc tgccgaggag
    43261 aagaaaaata taaagatatg ctgatggaca ttgcaacaga agaaatcggc cacgtggaaa
    43321 tgttggcgac aatggttgct cgtttattag agggtgcgcc tgttgaagat caagaagcag
    43381 cgatgcaaaa agatccaaca atcggtgcca ttatctctgg aatgaatcca cagcacgcga
    43441 tcgtagctgg cttaggacct cgtcctgctg acagcgtggg caatccatgg agcggtgcct
    43501 atatcattgc gagtggcaac ttgttagcag actttagagc taatttaaat gccgaatcac
    43561 aaggaagact tcaagtagca cgtatttacg aaatgatcga tgatcgtggc gtaaaagata
    43621 tgctgtctgt tctccttgca agagatagct atcatcaaaa tctatgggaa tgtgcagtga
    43681 aagaattaga agaaaaagaa ggttcaatct tagtcccaag tactttcccg cgtgacaaag
    43741 aacgaaaaga cattgcttat gacttctata acttctcaga gggagaccaa agtagtgaag
    43801 gttcttgggc tagtggcaaa gcactggatg gcgaaggcga atatcaatgg ttgaaagaac
    43861 ctaagatcga aggcgctgca ccaaaattag aaccagtaac accaaaaatg tatgggacac
    43921 ctccattcaa gaaataaata tctacccgta gaaacacccg ttttttgttc cacacgcttt
    43981 gtgagcaaaa ctgactaaag tcattaatca taaccaccct tcaaaagggt ggttttctct
    44041 agagctataa gctcaaatca ccggccagcg cctaaagacg ctggctttca tattttatgt
    44101 tcaagccata ttgcctttgc cagttttgcc cacctcttaa aaggtttatg tactactcct
    44161 tagcccttaa aaggatcgtc ttactctcgt acactcagct tatctaacgc actatcatgt
    44221 ttttcttgtt cttgaatgta ctttttgatg gtcgcttcat tttgtcctac ttttgtcaca
    44281 tagtatcctt ccacccaaaa gtgtcgatac ccaaatttat attttagatt tgcacaatct
    44341 cttgatgatc tcctgaatat tggctcgata ttgattataa attatttttc ttctatactt
    44401 tggtgtgaat acaatgtggt atttacacat ctactttgta cgggctaaac tatttccctt
    44461 tattgctcca cccgcatagc aagtggtttt gtatttcaat cgctcggcgc gctcaattag
    44521 gtctaaagac aataaatcta aaaacccgct gcttcactga cagaaacaac gggttttcag
    44581 aaaaaaatga aatgaaaaag atctcttacg gcaatctatt ttattttttt gattttttat
    44641 aaatggaaaa tgcttcaaga agtccaagaa ataaagccgt ataaaaacaa gaacctatga
    44701 aatctttatt tattagatat tcaacagaaa tcccgataac actagccaac aatatattta
    44761 tcagaagtgt aaaataagga tgctttttat agaatagaac tagtgttgtt ttcatagact
    44821 ctcctttctt catatttcca attaatcaca aattcacggc attactagaa aaattaaagg
    44881 ggcgcagaag tggaaaaata ctcttcgact ttccctacaa accaggccat cttgtgttta
    44941 ataactatac caaatctaag gtacctctaa atctaaattc catttgtggc ggtgacctcc
    45001 aatttttaac tcttctatct cccatccagt atacataacc ttgatacttc gaccacttat
    45061 atatcgaaca cacaaatacc tatccattgc aggagtacta cctaacttag ttgctacttg
    45121 catctaaata acagctgaaa agataggact tactcttagt aaagtatctg aactattaat
    45181 ttttaaacta tcatttttat cctcaactac atgcacatct gttgcaactt cactttctgt
    45241 ctcatccaga taaatgatta aggaatcggg aattgcaata tcttcagctg acgctggaat
    45301 agttgagcta aattagtcat catatcttta ttataaaata accaacagca aaaaatacaa
    45361 tgaaaaacaa acttggaact aatgtatcat taataaatgt tgaaaaattc agcaactcat
    45421 tactgtatga ttttagcagc ccaaccaaca tataccctat aaaagctaat aagatggtta
    45481 ggaatccttt agaattttta ctcattcata gacacttcct taaataactt ttattataga
    45541 aggtattgta aataataata ttgacaaaaa gtgactcaaa ataaaaaaaa ccttacatta
    45601 tactggaatg aactgtattg atagtgtacc taaaagctct actgacataa gatcgtgtaa
    45661 tcggtaaagt aattttatta attatacggg atgtaatcaa ttagagaata aactaatcat
    45721 aaaaggtact tttacattca taattgtcgc tttgagattc tactttggtt cactatctga
    45781 cccaattgca cattttcgat cattacaagt attggtgtcg ttagaacaac taaataaaaa
    45841 ctagcggtag atttttcaga atctatgcta atttctgtat ggatgttcca gtgatggcaa
    45901 atttctcttt tcattgtttt tcttgtcgca tgatatgcct ttttgtgtta ttcagttaaa
    45961 ctatagaaat tctttcctag acagatcttg atcccaaatt ttacgttttt gagcatcgat
    46021 atagtttaaa atgacattac tcatatctaa agagtttaga ttttttagga ctaaaactgt
    46081 cagttgttct ttttcttctt tctgttaaag tattgtcgcg acttttcgta tacgttaaga
    46141 tatgtcgtga aaaaacaagt tttgtgacac aaaaaaacga atgacttgag gaaatcacct
    46201 caatcattcg tttaaaatgc tatatattct ttagtttaag atacggaaat taatgccatc
    46261 gaccacacta gtagaatgaa cgacatttac ttggcctttt tttaatttcg ttatgtttag
    46321 catataaaaa tattatagag tttacttaca atgcttaaaa catatactgt ataatctgat
    46381 caattttagc catgtcttgc aatggtaagt tttctatttt tttgagtttt cgttccttaa
    46441 aatcaagaga ttttaattgt gtaataatta cttgtccttt tatatctagc tcttcaggta
    46501 atgagtaacg tgtcggtaaa ttctttatag tggaagtaat tggacatatg accgaaaaca
    46561 ttgttttacg gttaaattca taacgagaga cgactagtcc tggtcgtctt ttttgaattt
    46621 cttttcctac ggagggatca aaatcaatcc atacaatatc acctttttta ggaatataaa
    46681 ttctttcttc tgacactata aaatttctct cccttcagga gttaaatctt cccattcgtc
    46741 tttctcataa tactcggcct cttccccacc actaaatgga tcttcaattt ttggaactaa
    46801 cgtaattgtt ccatcatcag aatacacaac gatatattct tggttttctg aaggtttctt
    46861 tccgttatca gaaggtaaag ttaccactac agaacttcct tgtaatctag attttgtaac
    46921 aagcattatc atcactccct taataaaagt atactatata acactaagta acgcaaaatt
    46981 cccctttgta aactatctag aaaattgttt tgtttaaagt atatcttatt ggatataaat
    47041 agaaataaat tgtagccagt tcattttttc tttaactaaa aaaataatcc aagaaacatt
    47101 gaacctatgg atccaaaagc tacccaaata ctatagctaa ccccccgcta ccttcaattt
    47161 tgcagataaa acgctttggg agaaaatttc aaagacaaca ggccatccta tcatgcccga
    47221 ttataaacaa aaagctggct attccttttg ctctgacaaa tttcaattgg gaaagttcac
    47281 gaaactagca ggtgaagaag tttcaactgt tcggatcaaa gaatgcccgc ttcaaataga
    47341 aacattggtt caacgaattt caactagaca agactttgct attgtagaac gtgagatcgt
    47401 agctattttt gtagaagaag ggattttaca tgatccaact catatcaatg tggataaatg
    47461 gcaacctctt atctataaat tcagagaata tacaactgcc aaccagtcgt taactttgaa
    47521 ttttagattc caagaattca aagagtcata atgataaaca tcgttaggta taaataaaaa
    47581 agactcgcag cacgagtaaa aaacaaatag aagctataca ttagaaaggt cgactgtgac
    47641 cctatagatg cagtatatgc agcttatgag catttcttct gttctctttg tttttgggat
    47701 ctgtgctgaa gtctttttcg ttttttgccg ctctttcttt gaaaaatcga ttatgttata
    47761 ccttctccat tactaattca ggcatctgct gagtaatgat ttttcgcgca aaagaaatat
    47821 ctgttaccca aggttcgatt tgttcttcag tcaagacaag cggcattcgg tcatggattg
    47881 gtgcgactgt gcggttaggt tcagtagtca ttatgattga ttctgccatt ttttcatcct
    47941 gatggctacg ataaaaaccg ccaatataca ctattttttc cttatttgaa aacataaatt
    48001 tgtctttttc ttcattccac tcattgggaa aacacaacga ttttgcaaaa atggttgatg
    48061 aaaggtcttt ttttcttcta ctgtctctgc acgggcatta atcatcaatt gtcctttttt
    48121 aaatccggta aatccccact tcatgatttc cggagtgagg atgttttctt cctcttttct
    48181 taacgtcaca acaagatttg acggaaaaac ttctccagct gctaattctg ctgcctgctt
    48241 cggttgtttc gtctgggctt ctcgataata attctgaagg agctctgact ctagatcaaa
    48301 aaaataacga ccacacatcc taatccctcc caatcttttt ttctatcata cactgcaaca
    48361 agaagttcgc accaacaaaa cgctttcaat ttttgtagaa ctaaaaaagt tgtgacaagt
    48421 gacaaactct ccagtgaatg gtattctcct gccaactcct cggtcacaag tcacaatatt
    48481 caacaaacat gagaagctgc tttttgaaat tgttccttgt gactcggagt gaaacggcag
    48541 gcttacgacc tctgggtaaa cggtgttcaa aagccagttt ctcggtatta agccaaattt
    48601 atgcaaaaat gtagaaagct attttcacaa aatttttctt aatactcgaa actaagcgac
    48661 tttttcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca
    48721 accaaacgaa aaatatgagc agctattttt atttggctgt tcttattact tgatgcaggg
    48781 cagctttttc acaacctctc cactaaacgg tgttcaatca gctaaccttc ggtattagct
    48841 caaaaaacgg caaaatatga ggaactattt tgccgtttgt ttctctaata ctcaggtcaa
    48901 agcgctgatt tcacaacctc taatacacgg tgttccagaa gtagcttctt cgaaaaataa
    48961 gccgaaattt cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag
    49021 ctgaccactt ctgtcacaac ctctaattat taaagaacct tttgcgaagt taacaatctt
    49081 tctttgatca attgaaaatt ctgcctaagt agtgatagat cctgtgtgac tttcaacaat
    49141 aagatacttc cctggatttc agcaatcaac gctttggctt gacggtctgc ttcttcatcg
    49201 gacagttttt cttcagaaag tgccaggata ttttgtttcg tatacttgac ccattgattg
    49261 actaattcta gtagcaacag acggtattct tcatccactg tactcaactc aataatcaaa
    49321 ttacctacag gacagccatg ataagtgatc tgtgtctcat gatcagcgaa aatccagtcc
    49381 aacatttctt ctaatgcttc ttctggctgt tttccagcat ttaagatgtc ttcgaacaat
    49441 tctgtctgcc atacgtccat atgcgcatgg atcaccgcta gacaaacttc tttttttgaa
    49501 gaaaagtaat aataaaattg accttttcct gtatcagaag ctgctagaat atctcggatt
    49561 gacgtttcat gatagccttt tttataaata agatctttgg tcgcttccaa gatcttttcc
    49621 tttgttttca atgatattct cctttttcat ttctcatagt cctatattat acagtaaatt
    49681 catcattttt tcttcttaat cgtttaaaaa agactgtgcc aaattatctg acacagccct
    49741 cactataaaa ctgttctcat atagctagat gttcattgat tcaagaactg cgaggacaaa
    49801 agcaattcct atcttatgat agttgctcta atacttcctc tgttgtcatc acttgatctg
    49861 caataaagcc aaagttcgtc aacgctgcat ccattgcttc ttggccagga gcaccaattg
    49921 catctgtcgc taccacaaca ttgaatccac tctctaccaa ttcacgcata tgggaatcgc
    49981 tacacaagtt tccgttcatt ccaccaagaa ttactgtgtc gattccattt tttctcaatt
    50041 ggagcgccaa atcattgctt tctggtccaa agattttatg aggagagctg atgatcgtat
    50101 tttcatccaa ataaggtttc aattcttcga taaaatcggc tcctgaacct tcttccactg
    50161 attcatattg actttttcta gcaaacatct gctgctcaag catcatatgt tctcctgcac
    50221 cgccaaattg ccatttatgg tcatgtgggt aaaaataatg aggagaaata aagagtttgt
    50281 atcctttttc ttttgcttgt tttaccattt caatcatatt ttcgatcgta ttgtattttt
    50341 ctaagatatc ttttgtcaaa ccaaagccac cgcctgctgg tttcaagaac tcgacttgcg
    50401 ggtcagtgag aactactgct gtatttttat tattgaacat ggtggattct ccattcgtta
    50461 tttattttaa tacatcattt agagcttcac tcattgtcgg atgagaatag atttgatctc
    50521 tcaataacgt ataaggaagt tttccattca tagctagcga aatcaagttg atgacttcat
    50581 gagaatcttc cgcatagata cttgccccta gaatcaagtc agtttcaggg tcgactaaaa
    50641 ctttgaatac acctttagga tcttctaata cttgtgcttt agggacaccg cttgtcatat
    50701 acttgaataa tttgtaattg acgccttgtg ctttggcttg tttttctgtt aaacctacat
    50761 tggataaagt cggagtgata aatacactgt aaggcacagc tttccggtta ttcgttgttc
    50821 gtttattctc gcccttcaac tgatccataa tgattcgata atcatctaga gagatataag
    50881 tgaactgcaa tccgcctttg acgtctccaa tcgcccaaat gttgtctgca tctgtacgaa
    50941 ggtattcatc cacagcgatt gctccgcgat ctgttagttt aacatctgta ttttctaatc
    51001 caagtgatgc tgtacttggt tttcttccag ttgcagccaa aacttttgac gcttggattg
    51061 ttacttcttg gccatcttct gtaaaggtga cggcagctgt tgattcttgg tctgctactt
    51121 gatctacaga tacacctaga tggaattcga ttcccgcatt tgtcatgtct tctaaaatca
    51181 tttgcgcgat atcttcatct tcacgtggaa gaaattcaga atgggcatca agaacgacaa
    51241 ctttagatcc gtattcattg aacattgatg caaattccaa gccaatatat ccagccccga
    51301 tgatcactaa tttttccggt aattgttcct gatccatcgc ttgcgtagaa tcaatcaagt
    51361 agcgacttgt attcaatcct ttgattggta aaatgattgg ttcagaacca gtattgatga
    51421 aaatccgttc gccttcaaca atcacttttt caccattatt cgtcacttcg atttgatggt
    51481 tagaaagaaa acgtgctgta ccgtccatca ctgtcccagt tgcctcatcg ctgatcatat
    51541 gataattttt ggcgcgaagc atgcccgtca atttttcttt ccgagcaaca gcctctgtaa
    51601 agtcgattcc tctttctcca ttgaaaatca atgatttaga aggaatacag ccgatgttga
    51661 tacatgttcc gccatacata cgtgttgact tttcaacgac taaaaccgat tcaccttttg
    51721 aagctaacgc cttcgctaaa gtcttaccgc cctttccaaa accgatcaca atattttgat
    51781 atttttccat catttttccc tcgcttcttt tttacctacc gattggtaca aaaatatgat
    51841 aaccgataat tgtctattct ccaaatcatc tgctttattt gtcaaaaaaa accagacaaa
    51901 aagcggtcct ttcacgtttt tagtctggtt cgatttcctt tattcttcta aacaatcgtt
    51961 acttctacat cgatatttcc tctagttgct ttggagtaag ggcagaattc atgcgcatct
    52021 tctgcaattt tttgggcttc ttcttcgctg atgccatcga tatgcacttc taatactaca
    52081 ccgatctgat agccgccatc atctaaatta taaagagaga cacgtgcttt tactgtggac
    52141 tctgctgtca ttcctgcttc tttgatcata tgttgtaccg ccccattgaa acaagaagca
    52201 taacctgctg caaataattg ttctggattt gttccttctg catggattcc tggaggagtg
    52261 attttcatat gcatcgagcc atttggtgcc tcgacttctc cattgcgccc gccatggttg
    52321 atcattgctg tttcgtatgc ttttttcatt gtactgctcc tttcgattga ccatttgcta
    52381 cttggctata attatagtgt atgacaagta aggcgctttc tacaaaaatt ctgcttattc
    52441 gaataccaga atgccgtctt ctactatttt tccaaaaaac aaaaaaatac tactcgtgaa
    52501 caacagcgtc atatttgttc caaaataaat agcaatcttt tctacataat cttttatatg
    52561 attgatttta agatacatat ataccagaaa gttgacccca taaaccaata ctgttaaaaa
    52621 aataaccata ttcgttacca ttttttcctc cttttgctgg tctccctacc agcactcgat
    52681 ttaaccatac cacttttttt gccgtccaag caactagcct ttcaaaaaga ctggtttatt
    52741 ctgctgttaa tgattcaaga tcagaaaaat gtccgaataa ttttgctaat tttactaacg
    52801 ccaacttgtt ctttccgaat tcatcatttt ctatctgtaa tactagtaac ggctcatgta
    52861 agcttaaacg gatcaaaaac cagccgtttc cgtatggctc ttctagatca tatcgaatac
    52921 cttcttcatt ttccgggtcg aagttcatcc ctttttcttc ttccaacagt cgcttcattt
    52981 cttctaatat cttgtttcct tgttcgcgtg gttcatcgct gaacaatttt aatcggattt
    53041 cttgtacttc tacgggctgt ttcaactctt tgatttgttc atctaatgtg ataccttttc
    53101 tttttaattc tggcaaaagc atcaggatct ttgcgatgac atatgcacca tcatccagaa
    53161 aatagttttc cttgaatgca gcgtgtccgc ttgtttcgat ggctagctgt gtatctttcc
    53221 caagacggtt aagttctaat gctttattga ttacatttcg atagccggaa atataacgaa
    53281 cttggatgcc tcctttttct tcaatgaatc tttgtagatg agaagaagta ggggaattcg
    53341 tcacgattct tgttcctgga tgctctttta atacgattgt acttaatact gcgatcaaat
    53401 tatttcgatt gatcactgtt ccagaagcac tgacaactgc agaacgatcc acatctgtat
    53461 cgaaaatgat cccaagatct gcttcatttg ctaaaacagc ctgcttgata ctttccatcg
    53521 cttctttatt atcaggattt gggatatgat taggaaatcg gccatctggt tccaaaaatt
    53581 gggaacctgt tgaatccgca cctaagctat tcaatacttt ttcagcaaag aatccaccag
    53641 caccatttcc ggcatcaaca atgattttcc aaccatttag tggtttgctt tctagtgttc
    53701 caatcccctt tttaattttt gtgactaaat cttgcgcata aggtgtcaaa aggtctgctt
    53761 tttctacgct tccagtttgt tcgcttttta ttttttgctg ctgtgatagg ataaaagcaa
    53821 tatcttcttt ttctgctcct ccttctgagg taaagaattt tattccatta taataatagg
    53881 gaagatggct agcagtcagc ataaccgcag catcgcacga gaactgttca aattgagtgg
    53941 acataaacat agcaggcgta gtagctaatt cgaaatcgat gacatgtatc ccttgttctt
    54001 tcagactttg gatcaacgcc tctttcagtg ctggtccgct tatcctactg tcatgaccaa
    54061 tcccaatcgt ccatttttta tttggatcgg ttgatttctt ctttttcttt atccagtttg
    54121 ctagtcccca gccgatcttt tttaccatgt ctgtcgtcaa gtttacttca tatccttcaa
    54181 ctggtaatgc gattcctcga atatccgatc cattttgcag cgctttcata tctttcatat
    54241 aaaagtcctc ctcatttatt ccctcatttt ttccagcttt tctgcaaatc gctgtgcttc
    54301 ttcttctgag cggcaaataa taatgaatgt atctacaccg gccatcgttc cgacaacttc
    54361 agggtaagcc acttcatcta gccaattcgt taccacatcg gcaccatttc gttcagtcaa
    54421 tacgataacc atgaactgaa cagactggat acgcaaaacc tcgcgtctaa ttgctgtacg
    54481 caaacgttct tcatttaaag aaacagatgg ctggttaaat aatgtatagc gtactatttt
    54541 gttttcattt tgacttttta ctaacttcat ttctcgaatg tctcgagaaa tcgttgcttg
    54601 agtcacatcg gcgcctgctt catgcagccg cgcaagcagc tcttcctgtg tcccaatagg
    54661 ttgttctgta atgatctggc ggatcagtgc ttgtcgctgt ttctttttca tattagacac
    54721 ctctcaatgt tgattatagc aaaagataag taatatttct tcatattttg gtatttttta
    54781 cttttatttt ttgttttcat tcaggttgct aacctttttc tattttaaca cgcaaaatcg
    54841 tcttcatttt ttcaggtgct gattttcttg gatcgctgat gtaaatctct ttgtgttctt
    54901 tagaagctct ttcatagcct tcttttgcga tgaatgcttc taatttctca aacgttgctg
    54961 gttcttcggc atagggcccg acgtgtaaga tttgggcaca aagaccttct tccatctttt
    55021 tgaatactac ttgttctttc aagtcttccg gaagtttgct agaacgctga atggcttctt
    55081 gtgctatcgc ttctgtaaca aagtcaggct gtcggatcat caattgataa gaaaaatgtt
    55141 cttttttcat cactggttca tgcaaatact tttcttgcag tccccattgt ccttccagtg
    55201 gatagacagt atacatctga taatcaggaa tcagccaatt ttttttaggc gacatgcgta
    55261 ttgcatagct gactgcatat agacaggcta ctcttcgttt aaagtcttcc tgattcgggt
    55321 cgccgatccc tctgatgcta aagaatgatt ttttaggaac ctctagtatt tgcgggcttt
    55381 ttttcatact atagctcttg tctttacgcc attcaatttt ttccattttt cttcctccgc
    55441 gaaattccat ttagttattt attatcatac ctctttttga gtgacttggc taatcgtgtt
    55501 gacactattt ttcagtttgt gctagaataa gtgaagtaaa taaatcgtac agataacacg
    55561 tttcggcgtg tcgagagaga ggcggtttct atttttataa tagaaatcac tctctttttt
    55621 tacgaaattt tttagaggtg atgtaaatga caaaacaaaa acagctgctt ttagtacctg
    55681 cagtaattgc aacagggatg atgtcttttg cgggcgtatt gatcgagacg gccatgaatg
    55741 taactttccc aactcttatc agacagtttg atttaacgac tgcacaagtc caatgggtaa
    55801 caacgattta tcttttgatg atttcgatca ttgttccgct gtctacttat ttgaatcgca
    55861 attttagtct caaaaaactc tttttagctt caaatctgct tttcttggca ggtataatga
    55921 tcgatttctt ctctcctacc ttcatggtcc tattgtttgg tcgattgctc caaggtgcag
    55981 cgacaggtat cgctcttccg ttgatgttcc atattatctt gacatttgcc cccctcaatc
    56041 gacgaggcgc gatgatgggt gtcggtactt tgacaacggc cattgctcca gcaattggcc
    56101 ccacttatgg aggcattatg acttcacatt ttacatggaa tcatatcttc ctgtttcttg
    56161 tgcccgtttt gtttctttct ttgattatcg gctggtttgc tattcccgag atggcagtac
    56221 aaaaaagtgg ttatttggat tggataagcg ttttaggaat ttgtcttttg tttagtggaa
    56281 gtctaacatt tttgagtacg ttgggaacag tttccagctg gattgcttta atcatcggcg
    56341 gtattggctg gttccttttt tactatcgaa gtaaaaaagt ggagcatcca ctgatccgac
    56401 tgtctattct ttcaaataaa acattccgct tgtttttgat tggcttctta gtttatcagt
    56461 ttttattact tggtgtatct tttgtcttgc cgaatttcct tcagatcgtt caaggaagta
    56521 gtccttttgt cgctggatta gcgatgcttc ccggcgcagc ggttggtgct ttgctttctc
    56581 ctttttccgg gaaaatgctg gatcaatatg gtccgaagaa gccaattttt gctgggctga
    56641 ttctttcttt gattggttgg ctagcattat tcctactcat aggacacgct tcagtgggtg
    56701 tattgattgc ttgtcatgtg ttttatatga tcggtatcgg attatcttac agcaatatga
    56761 tgaccaccgg aatgaatgca ctgaatgaag aactacaagg agacgggaac gcaatgttca
    56821 ataccttgca gcagttttct ggcgctgtgg ctacttcatt agtagcggtc attatcaatt
    56881 acgtccagca tcatacttcc cataactatg aagtgtctac tacattagga tcaaaagcag
    56941 cattaggcgt cttgttgctg ttgcttctcg taagctttgc tcgattcgcc tattatctgt
    57001 tctttgctaa aaaagcgtag attccatata cggcaggtgt tgcatctgcc gtttttttgt
    57061 gtgaaaatgg ttgtttgtaa aaggaggctt ttttatggaa aaaattgcca ttatcggtgg
    57121 cgggatcatt ggtatgaccc tagccagtta cttagataca tcaaaattca atgttgcttt
    57181 atttgatgaa gggacaggac aggcaactaa agctagcgct gggattatct ccccttggtt
    57241 gtcgaaacgc agaaacaaac aatggtatcg tctggctaaa gacggcgctg cttttttccc
    57301 taaacttata aaagatttcc aacttgatca aacgatttac gcacaatcag ggacactttt
    57361 gcttcgacct gaaaaagatt tagctgaatt ggctgttctt gccgagaaac gaaaagaaga
    57421 agcgccagaa attggaaaca tcgaatggct ttcacctgaa cagacatctc aagcacttcc
    57481 gttattgaaa ccagcagttt cactgcgtat cagtggtggt ggtcgtctgg atggaaaagc
    57541 atatttagaa catcttggtc agcgtttagc acaaaaacaa atggagcaga tccaggcaaa
    57601 agtcactttg cataagaaga gcgattcttg gctcatcaag ggaccgtttg gagaatacac
    57661 agctgatcgt gtaattttga cacctggccc ggcacttaag cctttattac aagaattagg
    57721 ctatgctgca gatatacgtc cgcaaaaagg gcagctctta gcatttcaga catcttataa
    57781 gatgagtcaa gactggcctg ttgctatgct tgacggagaa gctgatttca ttcctttcat
    57841 ggatggaaag atccttttag gtgctaccca tgaaaacgat caaggctggg atttggctcc
    57901 tactagcgaa gcttataagg gattgactaa gagtacagaa cagttcttga ctgatccaga
    57961 tcagataaaa aactggccat acgagttccg tgtaggtacc cgtgcttata cgtcagattt
    58021 ttccccattt ttcggcgtac tgccagatga tccaagctta ctggctgcta gcggtctagg
    58081 ctcttctggc ttgaccacag gtccttatat cggctatcta ttagccaact tcttaaatac
    58141 tggtcattgg cctacggaag attatcaaaa ggacatctcc acctatatta cgaaaaatcc
    58201 atcatagaaa aacagctttt tcaagtaagg atcccgagcg atattgcgca tggattactt
    58261 cttgaaaaag ctgttatttt agttcaattt ctgaatcaaa ttctccaaac tttcttttgc
    58321 ttcatctggc aagagatctt ttcctatctg agcttcaatg aatcgtaaac gaatatcaag
    58381 tcgttgtttc accagatttt tataggacgt atcctcaaaa gaaacaggaa aatctggtat
    58441 aggtaaatag tggatgtctt caaatggacc aaacgacttg aattctgccg tttgttgcac
    58501 gattctttca acgattgaca atgtcgtttc aggtttgatt tttttatcat cgaaatatcc
    58561 agtattcagg acatagcagg ctgtttgctg tttcaaaaac aactctcgaa aagcttgata
    58621 gtcttcccta agaggataga cacggaaagg attagcaaat ggttcaatga ctagctcatc
    58681 tagctgtctt tttgtagtga tattttccgc gtctgatcgt tttgttgcta atgttgcacc
    58741 aaaagacgct gctaaaactg ggtcattgat cttgataatt ggcggaagcg aatcatcttt
    58801 catgatccaa aaaacagcat cgatcttttc gctaagatga tcgactcggt cgggtgtcgc
    58861 ataacgtgat ttgactgtcc gcccatttcc gtttcgtata tctcctgtta ctaggacttt
    58921 ttctccttta cttgtacatg tcacgcccac attctgacaa gtaaggaaag aagaaatggc
    58981 cggatcatca gacggatagt cttgtgtttt atcaaagtaa gaaggttcca aggcagtagc
    59041 aaaaccattt tttcgagaaa taacgaaagc atcgtcatgc aagatcgaaa cagagtgacc
    59101 ttccgtatgt tttgctaagg taatcgttga ttttccagaa ccggacaacc caaatacagc
    59161 catcgtatag gtctggtcat tactagcata ttgtttcatc ccaccgtggc aggcaataaa
    59221 gccattgcga tttcccaatg cccaagcaag cgtcaaagtc gcttttttta attctccaaa
    59281 gtaacgtaat cctagcacag ccgctgtatt atggagagca tcaaacaaaa tgagtccatt
    59341 tggaaatgtt tcatgtgtcc attcgggatc acaaaagata taaagatctc cctcatcaaa
    59401 ggaaacagac ttttgataag tctctaagat cttcgaattc gctggctgaa aattcagcaa
    59461 ataagaatac aaattgttct caaatccttc tggaatcagc aaatgacttt gcacagaaaa
    59521 ttcttcagat aggccaacga ttacttttgt atggtaaaac tggcgcttgc gactttgata
    59581 cacagcttct cttaaaattt tctcgtattt gctttgttcc ttgtctaagt cctcaaagat
    59641 ccgccgagca cttgctgttc ttcccacaat gcttccatca ttgaatacta gtgtcctaac
    59701 atcagctggt aaatctagtt cttcagcatg tgagattgtt aaatctgtga tgatcgttcc
    59761 tggactccct tttgctagtt gataagctgt cttcctatca aaaacttcat gaacattatt
    59821 accgtaaaat gtcgtttcta caatcgatcg aatactggat aacagtggat ttccacttgt
    59881 gatttcgttt aattcgagac tctcttttgt actcatggct cctcctcatt ccctaaacaa
    59941 aaaaacgttt tctttattat acattattcg agtttttatt tgtactgctg cgctgtggga
    60001 agcaaacgag ttatttttca cacaaaaaaa ccgagaactt gaataaacaa gtttctcggt
    60061 ttcatcattt tccttttatc ggcttagtac cagccgtttg ctaaccagaa tgttttagca
    60121 gcatcccatg aaccataacg agatgttaca tattgttctg ctacacgttc ttgattggca
    60181 gctgaatagt cgccgtttaa gtatgaagca tctaattgat aacggccgat gtaacgtccg
    60241 ttagtagctg tgtatgaacc gcctgattct ttttgtgcga tccattcttt tgcagagctt
    60301 gaagttggcg ctgttgcagc agctggggca gcaggagcta cttcaactgt ttcaacaggt
    60361 gcaacgtatg tatgttcttg cgttgctgtt tcagttgtag atgctgtatt ttctgttgtt
    60421 ttgttttctg ttgttgctga agaatcattt gaagttggga ttgttaattg ttcaccaaca
    60481 taaatgcggt tgatgtttgc gatcgaattt ttttcagcaa ttgcatcgat cattgagttg
    60541 tctcctgcaa atttttgtga gatcttagat aatgaatcac ctgattttac tgtataaact
    60601 tcatcagcgt gagcatttgt agttcctaca aacattgcag tagcaccagc agcaaaagtt
    60661 gtacctaaaa caattttctt aaatgaattc atattaaact cctttttttc tccgtttttt
//
LOCUS       DAFLWZ010000008        59114 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000008 DAFLWZ010000000
VERSION     DAFLWZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.008"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            24..542
                     /locus_tag="L1V38_000521"
     CDS             24..542
                     /locus_tag="L1V38_000521"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1315096.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            670..1353
                     /locus_tag="L1V38_000522"
     CDS             670..1353
                     /locus_tag="L1V38_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBN1315097.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1662..1735
                     /locus_tag="L1V38_000523"
     tRNA            1662..1735
                     /locus_tag="L1V38_000523"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1696..1698,aa:Arg,seq:tct)
     gene            1894..2253
                     /locus_tag="L1V38_000524"
     CDS             1894..2253
                     /locus_tag="L1V38_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBN1315098.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2376..4007
                     /locus_tag="L1V38_000525"
     CDS             2376..4007
                     /locus_tag="L1V38_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBN1315099.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4069..4710)
                     /locus_tag="L1V38_000526"
     CDS             complement(4069..4710)
                     /locus_tag="L1V38_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1315100.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4896..4972
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4992..5300
                     /gene="rplU"
                     /locus_tag="L1V38_000527"
     CDS             4992..5300
                     /gene="rplU"
                     /locus_tag="L1V38_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBN1315101.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5327..5671
                     /locus_tag="L1V38_000528"
     CDS             5327..5671
                     /locus_tag="L1V38_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBN1315102.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5684..5977
                     /gene="rpmA"
                     /locus_tag="L1V38_000529"
     CDS             5684..5977
                     /gene="rpmA"
                     /locus_tag="L1V38_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBN1315103.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6411..9218
                     /locus_tag="L1V38_000530"
     CDS             6411..9218
                     /locus_tag="L1V38_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1315104.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9409..9900
                     /locus_tag="L1V38_000531"
     CDS             9409..9900
                     /locus_tag="L1V38_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1315105.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10003..10992
                     /gene="manX"
                     /locus_tag="L1V38_000532"
     CDS             10003..10992
                     /gene="manX"
                     /locus_tag="L1V38_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBN1315106.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11025..11828
                     /locus_tag="L1V38_000533"
     CDS             11025..11828
                     /locus_tag="L1V38_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBN1315107.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11849..12763
                     /locus_tag="L1V38_000534"
     CDS             11849..12763
                     /locus_tag="L1V38_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBN1315108.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12846..13220
                     /locus_tag="L1V38_000535"
     CDS             12846..13220
                     /locus_tag="L1V38_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBN1315109.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13359..13604
                     /locus_tag="L1V38_000536"
     CDS             13359..13604
                     /locus_tag="L1V38_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1315110.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13776..14840
                     /locus_tag="L1V38_000537"
     CDS             13776..14840
                     /locus_tag="L1V38_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1315111.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15086..15511
                     /locus_tag="L1V38_000538"
     CDS             15086..15511
                     /locus_tag="L1V38_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1315112.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15504..15953
                     /gene="nusB"
                     /locus_tag="L1V38_000539"
     CDS             15504..15953
                     /gene="nusB"
                     /locus_tag="L1V38_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBN1315113.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16050..16904
                     /locus_tag="L1V38_000540"
     CDS             16050..16904
                     /locus_tag="L1V38_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBN1315114.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16905..18242
                     /locus_tag="L1V38_000541"
     CDS             16905..18242
                     /locus_tag="L1V38_000541"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBN1315115.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18247..18471
                     /locus_tag="L1V38_000542"
     CDS             18247..18471
                     /locus_tag="L1V38_000542"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBN1315116.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18473..19363
                     /locus_tag="L1V38_000543"
     CDS             18473..19363
                     /locus_tag="L1V38_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1315117.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19372..20190
                     /locus_tag="L1V38_000544"
     CDS             19372..20190
                     /locus_tag="L1V38_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBN1315118.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20297..20746
                     /locus_tag="L1V38_000545"
     CDS             20297..20746
                     /locus_tag="L1V38_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1315119.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20764..22446
                     /gene="recN"
                     /locus_tag="L1V38_000546"
     CDS             20764..22446
                     /gene="recN"
                     /locus_tag="L1V38_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBN1315120.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22501..22617)
                     /locus_tag="L1V38_000547"
     CDS             complement(22501..22617)
                     /locus_tag="L1V38_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBN1315121.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22690..23646)
                     /locus_tag="L1V38_000548"
     CDS             complement(22690..23646)
                     /locus_tag="L1V38_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1315122.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23817..24185
                     /locus_tag="L1V38_000549"
     CDS             23817..24185
                     /locus_tag="L1V38_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBN1315123.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24355..24786
                     /gene="mraZ"
                     /locus_tag="L1V38_000550"
     CDS             24355..24786
                     /gene="mraZ"
                     /locus_tag="L1V38_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBN1315124.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24807..25766
                     /gene="rsmH"
                     /locus_tag="L1V38_000551"
     CDS             24807..25766
                     /gene="rsmH"
                     /locus_tag="L1V38_000551"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBN1315125.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25771..26172
                     /gene="ftsL"
                     /locus_tag="L1V38_000552"
     CDS             25771..26172
                     /gene="ftsL"
                     /locus_tag="L1V38_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBN1315126.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26173..28365
                     /locus_tag="L1V38_000553"
     CDS             26173..28365
                     /locus_tag="L1V38_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1315127.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28391..29353
                     /locus_tag="L1V38_000554"
     CDS             28391..29353
                     /locus_tag="L1V38_000554"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBN1315128.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29367..30728
                     /locus_tag="L1V38_000555"
     CDS             29367..30728
                     /locus_tag="L1V38_000555"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBN1315129.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30754..31842
                     /gene="murG"
                     /locus_tag="L1V38_000556"
     CDS             30754..31842
                     /gene="murG"
                     /locus_tag="L1V38_000556"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBN1315130.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31857..33077
                     /locus_tag="L1V38_000557"
     CDS             31857..33077
                     /locus_tag="L1V38_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBN1315131.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33233..34558
                     /gene="ftsA"
                     /locus_tag="L1V38_000558"
     CDS             33233..34558
                     /gene="ftsA"
                     /locus_tag="L1V38_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBN1315132.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34581..35822
                     /gene="ftsZ"
                     /locus_tag="L1V38_000559"
     CDS             34581..35822
                     /gene="ftsZ"
                     /locus_tag="L1V38_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBN1315133.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35839..36516
                     /locus_tag="L1V38_000560"
     CDS             35839..36516
                     /locus_tag="L1V38_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBN1315134.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36530..37129
                     /locus_tag="L1V38_000561"
     CDS             36530..37129
                     /locus_tag="L1V38_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBN1315135.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37144..37431
                     /locus_tag="L1V38_000562"
     CDS             37144..37431
                     /locus_tag="L1V38_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBN1315136.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37480..38262
                     /locus_tag="L1V38_000563"
     CDS             37480..38262
                     /locus_tag="L1V38_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBN1315137.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38283..38990
                     /locus_tag="L1V38_000564"
     CDS             38283..38990
                     /locus_tag="L1V38_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBN1315138.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39252..42050
                     /gene="ileS"
                     /locus_tag="L1V38_000565"
     CDS             39252..42050
                     /gene="ileS"
                     /locus_tag="L1V38_000565"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBN1315139.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42099..43625)
                     /locus_tag="L1V38_000566"
     CDS             complement(42099..43625)
                     /locus_tag="L1V38_000566"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBN1315140.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43640..44287)
                     /locus_tag="L1V38_000567"
     CDS             complement(43640..44287)
                     /locus_tag="L1V38_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBN1315141.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44471..44800)
                     /locus_tag="L1V38_000568"
     CDS             complement(44471..44800)
                     /locus_tag="L1V38_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBN1315142.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44977..45705
                     /gene="sfsA"
                     /locus_tag="L1V38_000569"
     CDS             44977..45705
                     /gene="sfsA"
                     /locus_tag="L1V38_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBN1315143.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45721..46734
                     /locus_tag="L1V38_000570"
     CDS             45721..46734
                     /locus_tag="L1V38_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1315144.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46734..48011
                     /locus_tag="L1V38_000571"
     CDS             46734..48011
                     /locus_tag="L1V38_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1315145.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48074..50776
                     /locus_tag="L1V38_000572"
     CDS             48074..50776
                     /locus_tag="L1V38_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1315146.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50928..51245
                     /locus_tag="L1V38_000573"
     CDS             50928..51245
                     /locus_tag="L1V38_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1315147.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51275..51595
                     /locus_tag="L1V38_000574"
     CDS             51275..51595
                     /locus_tag="L1V38_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1315148.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51703..53163
                     /locus_tag="L1V38_000575"
     CDS             51703..53163
                     /locus_tag="L1V38_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1315149.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53231..53452
                     /locus_tag="L1V38_000576"
     CDS             53231..53452
                     /locus_tag="L1V38_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315150.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53483..53665
                     /locus_tag="L1V38_000577"
     CDS             53483..53665
                     /locus_tag="L1V38_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBN1315151.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53665..54078
                     /locus_tag="L1V38_000578"
     CDS             53665..54078
                     /locus_tag="L1V38_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBN1315152.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54201..55382
                     /locus_tag="L1V38_000579"
     CDS             54201..55382
                     /locus_tag="L1V38_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315153.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55453..55617)
                     /locus_tag="L1V38_000580"
     CDS             complement(55453..55617)
                     /locus_tag="L1V38_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315154.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55771..55844
                     /locus_tag="L1V38_000581"
     tRNA            55771..55844
                     /locus_tag="L1V38_000581"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55805..55807,aa:Arg,seq:cct)
     gene            complement(55913..57052)
                     /locus_tag="L1V38_000582"
     CDS             complement(55913..57052)
                     /locus_tag="L1V38_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1315155.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57351..57986)
                     /locus_tag="L1V38_000583"
     CDS             complement(57351..57986)
                     /locus_tag="L1V38_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315156.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58099..58734)
                     /locus_tag="L1V38_000584"
     CDS             complement(58099..58734)
                     /locus_tag="L1V38_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBN1315157.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58768..>59114)
                     /locus_tag="L1V38_000585"
     CDS             complement(58768..>59114)
                     /locus_tag="L1V38_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBN1315158.1"
                     /translation="EKTIPFKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKD
                     ENTVMFTKKYWNEMENLKKYIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQE
                     EFDFKKKELLGL"
BASE COUNT        19391 a         9987 c        12527 g        17209 t
ORIGIN      
        1 aataaagaaa gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta
       61 taacgttgat tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg
      121 gtttgactcc ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc
      181 tgatatatgt acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt
      241 atgaaaattc aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg
      301 aagattttta tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga
      361 gaaatattat cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa
      421 cggcatttgc atggattcag gggttattct ttacgattgc tttttgccta acaggaatca
      481 cagcatggaa tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt
      541 aagaatgtta aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca
      601 cgagaaaaca ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg
      661 aggagtagta tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat
      721 tttatgcgta cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct
      781 catgtagcag aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt
      841 ggacagcttc agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt
      901 gtcatggcca cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc
      961 atgatcgaga aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg
     1021 cttgaaggtc aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt
     1081 atggatagtg caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga
     1141 aaaggtggcg ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat
     1201 gaagagattc cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt
     1261 gtgatggatc atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta
     1321 atgacaaagg aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa
     1381 tcgattgaat cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa
     1441 ttaaaggata caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt
     1501 ttcaattgat aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag
     1561 tagttgggcc aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag
     1621 caatttaatt atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg
     1681 atagagcatc cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa
     1741 aaaccgttag aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt
     1801 gttttcaaag gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa
     1861 aaaataaaac tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg
     1921 actctagttg caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct
     1981 gacacgacaa gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa
     2041 acattgttta agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga
     2101 gcttatcttt cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt
     2161 gttgcattat atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta
     2221 gctctgttgg cattgctttc tattttctta taaatataga aaaaataaga atttatctaa
     2281 caggaaactt tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt
     2341 attttagaaa atttcatgaa aaaggagtta gataggtgtt caaaaattat gtttcctcac
     2401 taaaaaaaga attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga
     2461 tcacagtagc tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg
     2521 atgcggccgc aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag
     2581 gcggttttta tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg
     2641 cggcaacaaa gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac
     2701 ttgcagcagg acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta
     2761 cggggtttac ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg
     2821 gtgttcactc ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat
     2881 ttccgataaa cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct
     2941 atccaaaaaa atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag
     3001 cagttatgct attgttccat ttaccagtag caactgtggg taagattcca caaacattga
     3061 tcagtagtaa tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag
     3121 ttccagctat tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg
     3181 ctggccgaat ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg
     3241 gaaatctgtt gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa
     3301 gcgtggccat caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct
     3361 tactgctctc catgcttgtt tttgcgccag tgatgtcaca gtttccaatg ccagcacttg
     3421 caggtgtttt gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat
     3481 ttactaataa atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta
     3541 tctttgattt aagtattgct atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg
     3601 tcaaaagcgc tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc
     3661 cagaaacgga aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta
     3721 tgtcttcaga aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt
     3781 tctccatgcg aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc
     3841 aagaaaaagc agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag
     3901 aaaaacaact ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc
     3961 atgcgttgac agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag
     4021 aacagacaag actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg
     4081 taaaagtgaa gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta
     4141 gaaaatagct gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta
     4201 ggcatccttt tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt
     4261 ggtaaccgta tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat
     4321 taattttggc tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc
     4381 ggaacgagta ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat
     4441 ccgatgagtc acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg
     4501 tgttaagcca gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg
     4561 aacatgcgta tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg
     4621 aagaggtcct tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc
     4681 ttcttgtatc agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag
     4741 aataaaagaa acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga
     4801 agtattgctt gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct
     4861 gttctggtaa gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa
     4921 gtaataagca cagcatatgc tgtcacttcg gatggcgagt ctaagtatat cagaaggagg
     4981 tgctttatag catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg
     5041 gacaagcaat ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg
     5101 aagttatctt agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa
     5161 ctgttgaagg tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca
     5221 aacctaaaaa acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta
     5281 tcgacgcgat caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac
     5341 atttaagcga aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc
     5401 tggtccttat ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt
     5461 caacgggatt gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg
     5521 cggttatctt tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga
     5581 gattctatta gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata
     5641 tatccaaatt aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa
     5701 tctacaatta tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga
     5761 atcaaaacgt ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct
     5821 ttaccgtcaa cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga
     5881 cactttattt gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa
     5941 acaagtgtct gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt
     6001 tgtgacaaga cttttgtcac agcctttttt gtttataaaa ataaaagttg tagtggaggc
     6061 tacgaagttt actttgtctt tttacactta atattttttt gccaatttgg aatcaggatg
     6121 ttttgataac tatcgttttc aattgatgga agctatattg tttgctatca gtgaaataat
     6181 tatatggtaa acagtgttct ttttcttgtt tccattataa aaatcgtatc gggatttttc
     6241 gttcttttaa attgaacatt tctatctatc cgcgtgttat caacaaaaca aaatcaggta
     6301 aatagttgac gaaacagaaa taaatacata gtattatgtt ttgaagccta agtacaatag
     6361 tctatagaaa aggagcgata ccattggcaa aacgcattga ccgaatttat atgtatgtca
     6421 aagaaaaaac cgctcattta acaaaggcag aatatgatca aggagtaaca acacaggaaa
     6481 ttgctgaagt gttagggatt cagcgaacaa atagcagtaa agatctgaat cagctagtgc
     6541 gcgaaggaaa actgataaag acagacggac gaccagtacg ttacatatat caaacactcg
     6601 ttacgcacgt aaagccagtt acaaaacatg tagtcagtta caaagaaacg ccggtctctg
     6661 aagaaaaaaa tacactccaa atagatacta aggatatctt tgcaaaaatc attggagcta
     6721 acggcagcat gaaaaattca gtggaacagg caaaagctgc gattttgtat ccgccaagag
     6781 gattaaattg tttgattaca ggacctaccg gatcaggaaa gacttatttt gcacacgcga
     6841 tgtatcattt tgcaaaagcg catcatgtaa tagatgagga aacggaactg attgttttca
     6901 attgtgctga ttatgccaat aaccctgagc ttttgatgag tcatttattt gggtacgcaa
     6961 aaggtgcttt tacaggcgca gatgaagaaa aaatggggat tatcgatcaa gcggatggcg
     7021 gtatgctgtt tttggatgag attcaccggt tgccgcctga aggtcaagaa atgatctttt
     7081 actttatgga tcatggaact tacagtcgtc ttggggaaac aacgaaatcc catgaagcaa
     7141 atgtacggat cgtaggtgcg accacagaag acccaggttc ttctctatta gaaacttttg
     7201 ttcggcgtat cccaatcaat atcaaacttc cggcttttga aaaacgtcct gcaaatgaga
     7261 aagtcgattt agtaaaaatc atgattgccc acgaagcaaa ccgcacgcag cgaaagattt
     7321 ctttgacaga agatgtagca aaagcattga tcggcagtgt gacctatgga aatataggac
     7381 aattgaagtc aaatatccag ttagtatgtg cacgaggatt tctaaatcat atgcaatcac
     7441 ccgaaatctc gatcacaatc gatgatttga cagaagggat tcgtagcgga ttgattcaat
     7501 tagcaagcaa ccgcagtgca atggcagagc tttctaaaat attggagcca aagataactg
     7561 tagcaccaaa tgatacgatc atgaaaatcc aatcggactc ctatgagtta ccttataatc
     7621 tatatgatat catcggagat aaagcagctt tactgaagtc ggatggtttg gatcaagaag
     7681 caatcaatca tttcatttct acagatatca acatccatct gaagtctttc tataaagacc
     7741 atggtttttc ttttaatgca gacagcaaat tagcagaatt tgtagatccg aaaatcatag
     7801 aagtgaccaa tcagatttat gtaatggtca aaagatcttt accatatgag tttcagcaaa
     7861 actttattta tgctatgagc ttgcatatca gttctttttt gaaaaaaatc aacttaggag
     7921 aagaacggca tacgaatgat aacatccgtg agatggcttt tgattttcca gatgaatatg
     7981 ctgttgcgaa agaagtgcgt agttatatcg aaacgtattt tcaagtggag attccagaaa
     8041 gtgaagacta ttacttgacc gttctactcg tctcgttacg ggcaaatcaa gcaagcggca
     8101 gaatcggtgt agtcgttgca gctcacggaa acagcacagc aagcagtatg gtccaagttg
     8161 tccaacagtt gttagatgca gagaacgtac gagcagtaga catgcctttg gatatggatc
     8221 cgaaaacagc attggaccga attgaacgca atgtacaaga agtagatgaa ggaagcgggg
     8281 tcatactctt agtagatatg gggtcccttg cgtcgtttaa ttcgcaaatt caaagagaca
     8341 ctggaattcc agtacgtact gttgatatgg taacaacttc tctagttttg gaaactgtac
     8401 gaaaggtctc agtattaggg acagatctag atatgttgca tgaatcattg aaaaattttc
     8461 gaggttacgc agaaatatct tctgtagaat ctgttcagga agcaaaacct attcataaga
     8521 aaaaagctgt tttggctatc tgcgcatctg gcgaaggtac agcacaaaga atcaaagaat
     8581 tgatcgaacg agcggtaaac aagcgtcaag aaacagaatt agaagttcta gctttgtcga
     8641 ttgtggaagt gaaagaagaa ctgccagtta tccaaaaaga atatcagatc atagctacta
     8701 ctgggattac tgatttgaat atccaagccc catttattcc tttagaacgt tttattgatc
     8761 aaaatatcga agtcattttg gatcagttgc tgatggaatc agaattggag gaaactgaat
     8821 tcatctccct agatgaagag tcagctaaaa atacgtgtgt tgagtttatc tctgataact
     8881 tcatctttat taatggtagt aagttaatcg atccaatgtg gcaattttct acacaaatct
     8941 ctcagacgac gggaatcggc gatgaagaat atggattcaa aatcaaccta gtgatgcaca
     9001 cagcaggaat gatcgaacgt attattcgga atgaaccatt gactgtggaa gaaaacgaat
     9061 tgacaaatac aacgaatgat cctctttata gccaattggc agcctcagtt gttctgttgg
     9121 aagatcagat aaaagtaaaa gtgccgatag aagaaatgta ttatctgcta cgtctagtcc
     9181 ataatcagtt agataaaaaa gaatacactg tgccatgaat acacaaaaac gatacacttt
     9241 tatagtgtat cgtttttgtg tattggttaa gaatccttta aattcaatta gtgtatcgta
     9301 aaaaagttgg cacgcttttt gcttatagta gtgtgtgcta ggaggtggtt gttcacacag
     9361 aaatgatagg ggtttctgtg aagtagtgag gaagaaggag ttttgcagat ggatattcga
     9421 ttggcacgta tagatgatcg tttaatccac gggcaagtcg caacagtttg gtcgaagcaa
     9481 acaggtgttg aacgtatcat tgtgatcagc gatgtagtcg ctcaagataa attgagaaag
     9541 tttctactaa aagaagctgc accgccgggg atcacagcaa atgtaataac cgtgcagaaa
     9601 atgattcaaa tctatcatag tggattatta tcacgagcaa aagtgatgct tttattcacc
     9661 aatccccaag atgttgaagc ggttgtccgc tgcggtgtac agttgaagtc gttgaatatc
     9721 ggcggtatga gttttactga aggcaaatca atgattacca attttgtttc agtaaatcaa
     9781 caagatattg attcctttcg ttacttgaac agtcaagaag tggagttaga gattcgaaaa
     9841 gtacctgctg acaggaaaat ccttttgatg gaactactag cgaaaatcaa aaaggtgtag
     9901 caagaatggt tgttggaaaa ggtcaaataa ttctgttgta atggttagca attattaata
     9961 tttttgaatt tgttacaaca aaagtaaata ggaggtataa atatggtagg gattatccta
    10021 gcaagtcatg gacaatttgc tgaaggaatc ttacaatccg gttcaatgat ctttggcgaa
    10081 caagaaaacg tcaaagccgt gattttgaaa ccaagtgaag gtccagatga cttgagagcc
    10141 aaattggaag aagcggttgc ttcttttgat aatcaagacg aagtgttatt cttagttgat
    10201 ttatggggcg gaacaccgtt caatcaatca aacacattat tcgaagagca caaagataaa
    10261 tgggcaatcg tcagcggttt gaatttacca atgttgattg aagcctacgc atcacgcttt
    10321 tcaatggaat ctgctcatga aattgcagca cacatcattg aaacagcaaa agacggtgta
    10381 aaagtaaaac cggaagaatt agaaccggca gaagcaccga aagcagcagt tgaagacgca
    10441 caacctaaag gagcacttcc agaaggaact gtggtcggag acggaaaaat caaatatgta
    10501 ttagcacgtg ttgactcacg tctgttacat ggacaagttg cgacagcttg gacaaaagca
    10561 gtgcaaccaa accgtattat cgttgtttca gatgcagtat caaaggatga tctgcgtaag
    10621 agactaatcg aacaagctgc tcctccaggt gtaaaagcaa atgttattcc tattagcaaa
    10681 atgatcgaag tagcaaaaga ccctcgtttt ggaaatacca aagcattgct tttatttgaa
    10741 aatcctgaag acgtattgac agctgttgaa ggtggcgtag acatcaaaga attaaatgtt
    10801 gggtcaatgg cgcattcggt cggtaaagtc gttgtaagta aagtattgtc tatgggacaa
    10861 gaagacgttg aagcgtttga gaagcttgaa caaaaaggtg tgaaattcga tgtacgtaaa
    10921 gtacctaatg attcacgcga taacatggat gatattttga aaaaagcaaa agctgaatta
    10981 gcaaaagcgt aataaataat attaaaattt ataggaggct tatcatgtct attatttcaa
    11041 taattttagt cgtattagtt gcctttctag ctggtatgga aggtattctt gatgaatttc
    11101 aatttcatca accactagtg gcatgtacat tgatcggttt agttaccggt aacctcgaag
    11161 ctggtatcgt acttggcggt acgcttcaga tgatcgcttt aggttgggca aatatcggtg
    11221 ccgctgtagc accagatgct gcattagcat cagtagcatc agcaattatt ttagttttag
    11281 gtggacaagg tgttaaaggt gttccttctg cgatcgcgat tgccgttcct ttggctgttg
    11341 cagggttgtt cttaacaatg atcgtacgta caatcgctgt tccaatcgtt catttgatgg
    11401 atgcggctgc tgaagaagga aacatccgta aggttgaaat gtggcacatc attgctgtat
    11461 gtttacaagg ggttcgtatc gcggtcccag cagcagcgtt gctatttatc ccagcacaaa
    11521 ctgtgcaatc attccttgaa tcaatgccag catggttaac agatggtatg gctatcggtg
    11581 ggggaatggt cgtagctgta ggttacgctt tggtaatcaa catgatggct acaaaagaag
    11641 tatggccatt cttcgttatt ggtttcgttg tagctgcaat ttctcaatta acattgattg
    11701 ctctaggtgc tttaggtgtt gcattagctc ttatttactt gaacctttct aaaatgggtg
    11761 gttcatcaaa taatggaggc ggaagcaact ctggtgaccc tttaggcgac attttgaatg
    11821 actattaatc ttgaaggagg aaaataaaat ggcagaagaa aaaatcaaat tatcaaaaaa
    11881 agatcgttta gctgttgcgt ggcgctctac cttcattcaa ggttcatgga actacgaacg
    11941 tatgcaaaac ggtggctggg cattttctat gattccagca atcaaaaaat tatacaaaac
    12001 aaaagaagaa cgttctgcag cattaaaacg tcacttggaa ttctttaata cacacccata
    12061 cattgcttct ccaattttag gggttacatt ggctctggaa gaagaacgtg cgaatggcgc
    12121 gcctgttgat gatgtagcga ttcaaggggt taaagtaggt atgatgggtc ctttagctgg
    12181 tgttggtgac ccagtgttct ggtttacagt acgtccaatg ctaggtgcac taggtgcttc
    12241 attagctatg ggaggaaata tccttggacc aatcatcttc ttcttaggtt ggaacattat
    12301 tcgttgggca ttcatgtggt atacacaaga atttggctac aaagctggtt ctaaaattac
    12361 tgatgacctt tctggcggat tgttacaaga cgtaacaaaa ggtgcttcaa ttttagggat
    12421 gttcgtatta gctgcccttg tacaaagatg ggtatcaatc aaattcttac cagttgtatc
    12481 aactgtaaaa ttagataaag gtgcttacat cgaatgggat aaattgcctt caggtggtga
    12541 aggaatcaag agtgcatttg aacaagttaa taatggctta gccctttctc ctgaaaaggt
    12601 aacaacatta caagacaact tagaccaatt gattcctggt ttagctgcat taggattaac
    12661 attgttatgt atgtggttgc ttaagaaaaa ggtttctcca atcgttatca tccttggttt
    12721 attcgtagtc ggtgttgttg gacacgtcat cggactttta taatccataa aaatatagct
    12781 cgggcgttgt cccgagcttt ttttatatag tatactgttc ataaacaaat atctggaggg
    12841 agaaaatggt tcaatcaatc aatacaaaag tagacttggt aattgatgct acttcgttta
    12901 cgggtctgac agattacggg caaatcatga taggtaataa tggttttgag ttttaccatg
    12961 cgcgagatag acgcaaatat atccaaattc catgggaaga agtggattat gtactagcat
    13021 cagtcatgct aaagggaaaa tggattcctc gatatgccat tcaaacgaaa aaaaatggta
    13081 catacacatt ttcttccaaa gaacctaaaa aagtgcttcg tgcgatcaga gaatatgtag
    13141 atgaagatag aatggtacaa tcattgagtt tctttgatgt agtgaaacgt ggtattcgta
    13201 gtatgtttaa acgcaagtaa aaaataaaga aaacttctaa gaggaggttt tctttatttt
    13261 tttactttgc agaagaaaat atgaaatagc aaaaccaatt atttgtcccc tttaaatccc
    13321 atatgctaaa attgattagc aaagaaggag gttatattat gagttggtta tggacattga
    13381 ttgttggagc cgtgatcgga gcaattgcag gtgcgatcac cagtaaagga aattcgatgg
    13441 gctgtgtaac gaatatcatt gctggactag tcggttcaag tattggacaa gcgattttcg
    13501 gcgaatgggg accaaaagct gcaggtatgg cacttattcc atctatttta ggcgcagtga
    13561 ttttggtagc agttgtctca tttttctttg gaaaacgatc ataagttttt acaaaatagt
    13621 aaactaaaag gagttgcagc gagactgtga ctcctttttg gctttattta tttaaaataa
    13681 aaagaagttt tccggaaatt tttatttaac tgtcgtgtac gaagaaaagt ttgctataat
    13741 ggaaaaaagc gtgcaaagaa agagggagtt tcattatgat gctacgtgta gaaaaattgc
    13801 gcaaaaaaat gcaagaagaa aatttggatt catttttggt taccagtccg tacaatcttc
    13861 gttacttaac gaactttaca ggtacgacag gattagctgt tattactttg gaaaaagcat
    13921 tttttattac tgattttcgt tataccgagc aggcggcagc gcaggctcaa gggtttgaaa
    13981 ttattaaaaa tgtcggacct atttttgatg aggtagcaaa cttagtacgc aaagaagaac
    14041 tgcactcatt agcttttgag gaaacaacag tctcattttt agaatattcg gttttagaag
    14101 aaatcatcga tgcggaatta gtacctgttt cacagatgat cgaagaactc agagaagtga
    14161 aagatgaaga agaaatcgct attatcgaaa aagcatgtca tattgcggat atggcatatg
    14221 atcacatcct gaaaatgatc caaccgggca tgactgagat tgaagtcgca aatcaactag
    14281 acttttatat gcgttctctt ggcgcttcag gtgtttcttt tgatacgatc gttgctagcg
    14341 gattgcgttc ggctatgccg catggtgtag caagcaaaaa aatcatcgaa caaggtgact
    14401 tgatcacatt ggactttggt tgctattacg aagggtacgt ttccgatatg acacgtacat
    14461 tcgctattgg tgatcctggg gaaaaattaa aagaaattta tcaaatagtc ttagatgctc
    14521 aattagcagt tattgatgct gcaaaaccag gaatgactgg tgtccaatta gatgcagttg
    14581 ctagagatta tatttcaaaa catggttacg gggaagcatt tggacattct acaggacatg
    14641 ggatcggttt agagatccac gaaggaccaa acgtttcttc tcgtgcagaa aagcaatttg
    14701 taccaggaaa tgtgatcact gatgaaccag ggatctactt accaggaatc ggtggagtac
    14761 gtattgagga tgacttgttg atcacagaag atggaaatcg tgtgttgact cgttcaccaa
    14821 aagaattgat catcttatag tttcatcaat agaagaagta agcgtaaaaa tcagtgttca
    14881 cagactttgt tatagaaaat cactcgattt aatgatacac tatagaagaa cttttaagct
    14941 gtaagagata ataaagttgg gtgttttctc caattcatag cagtttgcag ctgatcggcg
    15001 gcagttttct taccacgtga tcactatgcc gcatcataga gaattcggat gtatctcgtg
    15061 cttaggcaaa gggaggaata aataaatggc agatgaaaaa aatttgattt taaacgcaaa
    15121 ccaagattta ggagagatcg tgatcgctcc tgaagtcatc gaagtaatta tcgggattgc
    15181 agcttctaaa gtagaaggcg tatacggaat gcgcggaact tttgccagca atgtcactga
    15241 attattagga cgtgcagctc acggaaaagg tgtttactta gcaaacgagg aagatggctt
    15301 gaaagtagat ctttactgtt atctagaata tggtgtttca gttcctaaag tagcaatgga
    15361 aatgcaggaa cgggtcagcc agcaagtcct tttcatgacg gatatcgatt tatctgaagt
    15421 caatatccat gtagtagctg ttgttcctga aaaattagaa caaccaacaa tcgaagaact
    15481 ttttgaagac gaagaggaag agaatgaata aagaattatc aagacacgag attcgggaaa
    15541 tggcattgca ggctttattt ccattagact tcaatgcaga cctaacaaaa gaagatgcga
    15601 ttttcaacgc aatcgaatta gaccaccgcg acatgatcaa cgaagatgaa tcagagtttg
    15661 ttcctgttta tcttgatacg ctagttggcg gtgtctgtgc aaaaaaagat gaattggata
    15721 aagtgattga aaaacattta aaaaacaatt ggcacatcaa tcggatctca aaaatggatt
    15781 tggtgatctt gcgtatcgcg atttttgaaa tgacttatgt gacagatgta ccagcggctg
    15841 ttgctttaaa tgaagcaatc gagttggcaa aaacatttag tgatgaccgt tcacgtaaat
    15901 tcgtcaacgg tgttttatcc aatgtattga aagaattaga agctggggcg taagtcctag
    15961 cttttttcta tgaatcatca taaacctgtt ataaatcggg aaaattctat ggtagaatga
    16021 aaacacaaaa aatatctggg agtggttaga tggcagaatt gattaacgga aaagaattag
    16081 ctgaaaaaat gcaggcagag attgctgaaa aaatccaaaa attgaaagat aatggtatcc
    16141 atcccggatt agtcgtttta ttggtagggg aaaatccagc cagccaaatc tatgtaagaa
    16201 ataaagaacg tgtagcaaaa gaaatcggaa tccattcatt ggtagagcgt tatcctgaga
    16261 cgatttctga agacgaacta cttgcagaaa ttgaaaaata caatcaagat cctagttttc
    16321 atggtatatt ggtccaatta ccattgccaa agcatataga tgaagaaaag atcctgttag
    16381 ctatccgccc tgaaaaagac gtagacggtt ttcatccgat gaatttaggc agactccttg
    16441 cgggtaaacc ggacaagatt ccttgtactc catacggcat catgaaaatg tttgaagctt
    16501 attctatcga tccggcgggt aaacgagcag tagttatcgg acgaagcaat atcgtcggta
    16561 aaccgatggc tcagctactc ttgatggcag atgcaactgt tactgttgct cattctaaaa
    16621 ccgaaaatct ggctgaactg gcacaagaag cagatatttt agtcgtagca ataggacgtg
    16681 gacattttgt cacaaaagaa ttcgtaaaac caggtgctgt agtgatagat gtagggatga
    16741 atcgtgatgc taacggtaag ctgatcggtg atgtgaaatt tgatgaagtg gagcctattg
    16801 caggctggat cactcctgtg ccaaagggtg tagggccaat gactatcacg atgctgatgt
    16861 atcaaaccgt aaaatctgcc gaagcttttg gagcaggtga atagatggca caagaatatt
    16921 taactgtcac tacattaacg aagtatttga aaagaaaatt tgatgccgat ccttatttag
    16981 aacgcgtata tttaacaggc gaaatatcga atttccgttt acgtgccaat gcccatcaat
    17041 atttcagctt aaaagatgac catgcaaaaa tatctgctat tatgttcaaa ggagcattcc
    17101 aaaaattacg attccagcca aaagaaggaa tgaaagtcct tgtcgttggg cgtatttcat
    17161 tatatgaagc gggaggttct tatcaaatct atgtagagca catggagcct gatggaatag
    17221 gtgctttata tcaagaattg gaagaacgaa aagaaaagct gatgaaggaa ggcctttttc
    17281 aagggcctaa aaaaatgctg ccacgtttcc caaagcgaat cgcggtcctt accagtccaa
    17341 gcggagcggt tatccgcgat atcatcacga cggtgaaaag aagatatcca attgtccaat
    17401 tggttttgtt cccaacagtt gtacaaggaa accaagcagc ggacaatgtt gtcaggaata
    17461 tccagagagt agaagagatg ggcaatttcg atacaatgat catcggtcgt gggggtggtt
    17521 cgattgagga tttatggccg tttaatgaag agcgggttgc tcgggcgatt tatcaagcta
    17581 atacgccggt gatttcatct gtaggacatg aaacagatac cacgatcgct gatttagtag
    17641 cagatgttcg ggctgccact ccaacagcag ctgcagaatt agctgttcct gttttgtcag
    17701 aagagttgat gcgcattcaa gaacggcaag ctagattgca gcaggcgttt gtacgccaga
    17761 tccagcgcaa acaagaacgg ttcgagcgtg ctcgacgttc ctatgtattt cggcagcctg
    17821 aaagattgta tgaaggtcag accatcaaat tagaccagtt gaaacagcga ttatatcaag
    17881 ctacacagca aatttatcat gcgaaagaaa aacaaacgat cgcattaagc caccaattgg
    17941 aacaagtggc tccgctttat cgagttaaag cagctcgcca agaaactgct tatctagaaa
    18001 aacgcttaga agagaaaatc caacaatata tgaaacaaca gcagcagcgt tttgctcaag
    18061 ctgttcaatc tcttgatttg ttgagtccat tgaaaatcat gggaagaggc tacagctata
    18121 cgacgttaaa tgatcaagta gtaaaaagtg tcaccgagat tcatcaaggg gatttgctga
    18181 cgatccatta tcaagatgga atcgttaaag gacaagtaca agagatagac aaaggagaat
    18241 aaaaatatgg aaaatccaac ttttgaagag tcactgcaag aattagaaaa aattgtcatg
    18301 cagttagaac aaggagacgt tccattagaa tcagctctag attcgtttaa acgaggaatg
    18361 gaattaagca aacattgcca agatacatta gctaaagcag aagagacctt gacgaaaatg
    18421 atgacagaat caaatgaaga agttgatttt gacggaaacg aggaaagctg agatgagatt
    18481 aactgacttt tcagctattc atctacctgc tgtagaaaaa gaaatcttgt cttttttaga
    18541 tgagcataca acggatagag gactctatga tgcgatgagt tattcagtga aagcaggcgg
    18601 gaaaagaata cgtcccttat tacttttaac ggccgttgct tcctttgatg agcctattga
    18661 tgttcccgtc tatcaagtag cagctgcttt agaaatggtg catacgtatt ccttgatcca
    18721 cgatgatttg cctgcgatgg acaatgatga tcttcgtaga ggaaaaccta ccaatcataa
    18781 agtattcggc gaagcattag ctatattggc cggagatggt ttgcttacag gagcattcca
    18841 gctaatcagt atggcacact taggtaattc tcctaagctt ctgctgcttc agcaattagc
    18901 tgtttgtgcg ggatcacaag gtatggttgc tgggcaagct gcagatatcg agggcgaatc
    18961 gaaaaagctt tctttagaag aattagcatt tattcatgaa agaaagacag ggcatttgat
    19021 tcgttatgcc ttgctggctg gtggcatatt agcgaagcaa cctgaagaaa tcttattgct
    19081 acttcaacga ttagccgaac atttaggttt agcttttcag ataagagatg atctactcga
    19141 tgtgattggt acaacgaaaa cattagggaa aacagctggt aaagatgaac gtatggaaaa
    19201 aaatacttac ccgcgtttat taggcctaga aaagacacgt gaggcgttgg agattgagct
    19261 gttatccgcc aacaagatca tagacaaatt agaagaggac gttttttctt ttgatggcgg
    19321 gctgatgcgc cagatgatca agcaatttga tgtggagaaa tgagggaaag aatggaaaaa
    19381 gaacgcgtag atgtattagc ggtcaaacaa ggattatttg aaacaagaga acaagccaaa
    19441 cgttcagtga tggctggttt gatttacaac gaaaaaaacg agcggtttga taaaccggga
    19501 gaaaaaattc cagtgagtag tgaattaaga gtcaaaggta aaaaacttcc ttatgtttct
    19561 cgagggggat taaaattaga aaaagcactc aaagcatttg atctatctgt tgaaggaaaa
    19621 acattgttag atattggtgc atccactggc ggatttactg atgcagcttt gcaaaatggc
    19681 gcaaaaatga gttatgcttt agacgttggc tacaatcagc tagcttggaa aataagacaa
    19741 gatcctagag tcgtcgtaat ggaaagagtg aattttcgtt atgcaaaacc cgaagacttt
    19801 accttaggaa ttccagaagt tgctgttatc gatgtttctt ttatttcact aaaactgatg
    19861 ctgcctccat tacatgctat tttaaaagaa gagggagaag tgattgcttt aatcaaaccc
    19921 caattcgaag caggcagaga agctgtaggg aaaaacggaa ttgttcgtga ccctcagacc
    19981 catcaaaaag ttttagaaga cattttgtca tttgcggcac aaggtggata tgatgtgctg
    20041 gaattaagtt attctccgat cacgggggga gaaggaaata tcgagttctt ggctcacttg
    20101 aggaaagtac ccgaaagcgg aacaatcaat tcagctatta atatggcaga agtggtttca
    20161 aatgcacacg aacagtttga ccataaataa attgtaactg tgaaaatcaa gtgagaagta
    20221 tgcggattct tctttattat accaaggaaa taagctatca ttgattaaga agaatatgct
    20281 aaggagcgaa gacgtaatga gaaaaaaaga tcggcatcgt ttgattactc gattgttgag
    20341 tgagcaagat atccgaaagc aggaagaatt tgttgaaatc ctgaaaagca aaggaatatc
    20401 tgttactcaa gctacgattt ccagagatat aaaggaactg aaactgatca aggtaccggc
    20461 ttcagatggc ggctaccgtt atagcatacc agctgaaaca aacgaagatg taaatactaa
    20521 attggaaaaa ctattaaaag acgctttcgt ggcagttgac caaatggaaa aatttgttat
    20581 tttgaaaaca ttgccgggaa atgcttcggc agcagcaaat ttgattgata aacgttacaa
    20641 gaaagaatta ttttcgatta tcaatgatga cgataatgtt ttgatgatta cacgaactga
    20701 agaccaggca gttttattga agaaagactt cctgcattac ctttaagttg aggagcgaat
    20761 gtgatgctac aagaaatcag tattactaac tttgcgatta ttccggaatt gcggctttct
    20821 tttcacgaag gaatgaccgc gctgaccgga gagactggtg cgggtaaatc cattattatc
    20881 gatgctttag gtctgttagc aggaggaaga ggttcaagcg attatatacg tcaaggagca
    20941 gaaaaatgtg tgcttgaagg gttgtttgaa ctaccaaaac aagaaggatt ctctgaactg
    21001 atggttgaat tagggatcga aacagatgag gacaatctga ttgttcgacg ggatatgtcc
    21061 ttaactggaa aaaatgtttg tcgagtgaat ggtcatatta tcacattagc taatctgaga
    21121 agaatcggca gttatttagt agatatccaa ggacaaaacg aacatcagga actgctccag
    21181 cctgaatcac atcttgcttt attggatcgt tttggagatg tagctttcca acagaagaaa
    21241 aagagttatc agcaagaata tatctcttat cgtgagctgg aaaaaagggt acgaaaagtg
    21301 cagcaaaatg aaaaatccta tgttcagaga atagatatgc tccatttcca gcaagaagaa
    21361 atagctgctg ctgatttgca agtcggagaa gaagagaaat taaaagaaga aagagaaaaa
    21421 cttagcaatt atcaaaaaat tgctgatgga ttagctgcag gttacggagc actgacgaat
    21481 aatgaacaaa acagtgtaga tggtgttggc ttggccgttt cagaactgca agggatcgcc
    21541 catctagatg tggagtatga agcaatttat gaaaatatcc aaagtgctta ctatttgctg
    21601 caagatgcaa tcggcgatat gagtcgtcag attgatttat tggagttaga tgagagtcgt
    21661 ttagaagaag ttacgcaacg tttagaatta atccgacagt tgaaacgtaa atacggcgaa
    21721 tccattgagt caatattggc ttactatgac gaaatcaccg aagagctagc ttcttctgat
    21781 ttttcagaag gtcaattgga caaaatgaaa gaggaactag agcaaaaaga gcttctactt
    21841 cagcaacaag ccgcagatct tcatgaagcg cgtaaaaaaa tcgcaaaaga attggaaaaa
    21901 tccattctgc atgaattgaa aagtctgtat atggaaaaca ctgagtttga ggtacgtttc
    21961 ttaaaagaag aaaatagaca attgaatcat gatggatttg accaaatcga attttacatt
    22021 acgaccaatc caggagagcc actgaagcct ttggtgaaag tcgcttctgg tggcgaactg
    22081 tctcggatgt tgcttgcttt gaaaactatt ttttcttctg agcaaggtgt gacaagtatt
    22141 atttttgatg aagtggatac aggtgtgagc ggaagagttg cacaggccat cgcagataaa
    22201 atttctcaaa tatcgaaata ctctcaagtt ttgtgcatca ctcatctgcc tcaagttgct
    22261 gcagtcgccg actatcaata ttatattgtg aaagcagtga ttgatggacg tacgcaaact
    22321 tctgtttcag agttgaaaac aaaagaaaga gaagaagaaa ttgcacgtat gctggctgga
    22381 agtgagatta caaaactcac actcgaacat gcaaaagaac tattgaaact cgcaaaaagg
    22441 acctgagcca cctcgcagtg gttcaggtcc ttttcagcag ctgatagcta tattttattt
    22501 ttacatgaca ctcattacag cagtcaatac aacagatcca atcgttaaaa tcagcattgt
    22561 ccaaatgaca aattttgtta ctttagcaaa agtacttgtt tgtttttttt cacgcattgt
    22621 tttcaacctc gtcattaatt agttgattca agtgtacaat cttttttcca tttccacaag
    22681 agggcttttt tataaaaact tccctttttt taaataatag gtagttacga tacaaataaa
    22741 taatgttaat agaactagcc atataaaggc atcatccctt tcagcaatag gtaacttaat
    22801 gttcattcca tagatactgc cgacgattgt cggtatagtt aaaataatcg ttaaagaagt
    22861 taaaattttc ataatattat tcagattatt cgatacgatt gctgaaaaag tctgattcat
    22921 ttgttctact agttttaatt gaatgcgaga agtagtcatt gcctgctctg tttccaccaa
    22981 tacatcacgt aaatgatttt tcaaagcatg attttcttgg aaaagtttat tttgcgctag
    23041 ttctttcaat gcatctaaat tagcagaagt cgcttctctg aaataaacga ggcttttttg
    23101 gatatccatg atttgataaa gttgtttgtt ttcagtggat acttgaagtt tggcttccaa
    23161 agtatcgcat tgagattgaa gcgtagctaa ataactgttg taagagagtg tgacctgcca
    23221 aatgaattga aagaagatat tgagattagg cgaaatatca ctttttggaa aggtctggct
    23281 aaagactttc tttaaaaaca gtggttcatg attcgtaatt gtgataagct tctttttggg
    23341 cgtcaaaata atagagagcg ggtatgtatc cacttgaaaa taaccgctag gacttgtttt
    23401 agcaaaagga tattgtaaca ataataacgc tggctttgtc aactttgatt gattgaattc
    23461 ttctgtacgg gaattttctg catcgtccaa tatggaagtg atgtaatctg acggaatttc
    23521 aaattgatgt gtcagctgat gaatctcttc ttgattagga cgttctacac aataccagat
    23581 cgtttggtca gtttcctttc cggtattacg cagtttctca ttatctaatg taaaatattt
    23641 gatcatgatt ttcctcctgt tgcctgtttc ttttattata acggataggg aattggaata
    23701 catggaatgt gtttgtaaga tatagaatat aactgcataa atttaaataa aatgaaacag
    23761 ttgtgtaaag tatatacagt atacttgaag caacgataaa aaaggagttt acgttcatgg
    23821 gcacattcac accacttatc ttgttttggt atatttaccc ggtaatcgtt ttgtttggtt
    23881 gccaatttct tgtaaaatta ttttcgttaa atcgtcgttt taaaataaaa gcccctgatt
    23941 tggcgattcc ttttttgtgg ggcggtatgc atgcattgtc tagaaataca gggacaattt
    24001 ctatcttacc gtttttcttt atttctgttt tgctaatggg aatttgtatt gctgttttcc
    24061 aagcatatta ttatgaagaa attatttatc cgcgttattt caagatgact tggcgtttgg
    24121 tttttctgtt gacaatcgtc ttgtacgctg tcttgatcat tgtgaacata ctttcttacc
    24181 tatgaaaaaa atagaaaagc tgtaaaaagt cttttaaaag gctttttgca gcttgatttt
    24241 taaaaaaatg tttatgaata aaaaaagttg ttcccggatt tcccagaaaa ggtggtagaa
    24301 agtgggggat tgtggtagac taattttagt tagtggagga atggggggct ttcaatgttg
    24361 atgggtgaat tccaacataa tattgatgca aaaggacgtt taatcgtgcc ctcaaaactt
    24421 cgtgaagaac ttggcgaaaa gtttgttctg acacgcggat tggatggctg tcttttcggc
    24481 tatccgatga gcgaatggga aaatctggaa gctaaactga acgaaatgcc gttggctaaa
    24541 aaagacgcac gtacttttgt gcgattcttc tattcggctg ccactgaatg cgaacttgat
    24601 aaacaaggac gaatcaatat acccagcacg ttaagaaatt atgcagcttt gacaaaaggt
    24661 tgcgtagtca tcggtgtatc taaccgaatt gaaatttggg atgagacacg atggcaagat
    24721 ttttctgcag cagcagaaga gaactttgac gaaattgctg aaagtatgat tgatttcgga
    24781 ctataagaat aggaagaggc tgactaatga ctgaaacatt tcaacactat acagtcatgt
    24841 tgaaagaaac ggtagatgga ttgaacatca aaccggatgg cgtttatgta gactgtacac
    24901 tcggcggtgc cggacatagt gaatatttat taagccaact aagttctaaa gggcatctgt
    24961 atgcgtttga ccaagatcaa aaagcaatcg atcacgccaa gctgcgttta gcttcttatg
    25021 tcgaacaagg tatggtcaca tttatcaaag cgaacttcag agaattagaa gaacgcttga
    25081 gtgagcatgt agataaggta gacggcattt tgtatgatct aggggtttcc tctcctcagc
    25141 tagatgaagc agaacgtgga tttagttatc atcaagatgc accgttggat atgcgcatgg
    25201 atcagtcagc tcctttatcc gcttatcacg taattaatga atattcctac catgaattag
    25261 taaagatttt cttccgctat ggcgaggaga aattttccaa acaaattgct cgtgaaatcg
    25321 aacgagtacg aaaaacaaaa ccaatccaaa caactggtga gcttgtcgaa atcattaaac
    25381 aagtcatccc agctcccgca agaagaaaag gcgggcatcc tgcaaaaaga atttttcaag
    25441 ctgtgcggat tgcagtaaat gacgaactcg gtgccgaaga ggcctcttta gaacaggcaa
    25501 tccggttatt gaaagtcaat ggaagaatca gcgtaatcac attccattca ttggaagaca
    25561 gaattgtcaa aagtatgttt aaagaatata gtacggtaca agatctacca ccgggacttc
    25621 ctgtcatacc tgacgaattc caaccagaac tgaaagtcat tactcgtaaa ccaatccttc
    25681 cttcagagga agagctaaca gaaaacaatc gatcacgcag tgcaaagtta cgtattgcag
    25741 aaaaaataag aatgaaagag gagtagaatg atggcagaat taaagaaaat gcaagattac
    25801 gaatatgatt tacctgaatt ggtggatcag ccggaacaac aaatgcctga ttcttcttcg
    25861 aatcaagaaa tcattcttcc acaatcaccg gcaaaacgat taaagcagat ttctgctttg
    25921 gaaaaaattg ctgtggcaag cgtggcgatt gctattgttg ctttatgtgt tttaacagtt
    25981 atgctgcgca caaatatcag cggagctgaa aaagaaatca cgtcaataca aacagaaatc
    26041 aatgataaaa agcaagaaaa aacgagttta gaacaagaaa aaaacgaact ttctcgtact
    26101 gaacggatta aacaaatcgc agaagaaaaa ggattgtcta ttaatgacga caatttaagg
    26161 aaagtgaagt aaatgagtct taaaaataaa attcggcggt ttatggaaaa gaaaaatcta
    26221 aatccgatga acaatcgcaa aaaagtaggt atcattttat ttgctacgag tattggattg
    26281 ttctttttat ttgccgtccg tttctcgtat atcgttattg gaggtcatgt tgctggtacc
    26341 tcattagctg aaaaaacaaa acagttgtac caaggaagtg aagtagtaaa agcaaaaaga
    26401 ggaacgattt atgatcgtaa cggtgtggcg ctcgcagaag atgcctcctc ttattcaatt
    26461 aaagcgatac tctcaaaaac atatacctct ggggataaaa aactgtatgt tgaagaaaag
    26521 aattttgata aaatagcaga aatcctgcat aagaatcttt ctatagacaa aaaagatgca
    26581 ctgaatattt tagaggacgg cgcaaaaaaa gagctgtatc aagttgaatt tggtagctat
    26641 gggaaaaata tctcccaaga aaccaagcaa aacatcgaag cggacatgaa aaaagaaggt
    26701 gtcgctggtc tttattttgt cgaccatcag gctcggatgt atccaaatgg cgtcttttct
    26761 tctcatttta ttggatacgc agttccagac aaagatgaga atggcttagt tggtaaacta
    26821 ggtttggagt ctgcttacaa tgatatcttg agcggtaaag atggtaagat tatttatcaa
    26881 aaagataatt ttcaaaatcc tctgccaggt acagtggcag aagaagaaaa agctgtcgac
    26941 ggacaagata tctacacgac tttagacagc agactacaaa gttatttaga aacactgatg
    27001 gatcaagtaa atgaagaata tcagccagaa gaattgacag cagtcctgat gaaagcaaaa
    27061 accggagaaa tcttggcaat gggacaacga cctactttca atcctgaaac aatggaagga
    27121 ttgactggaa aagatgctat ctggcgtaat ttcttggtac aagatagtta tgaaccagga
    27181 tcaaccatga aagttttcac tactgcagct gctatcgaag aaggagaatt caacgagaat
    27241 gaaaccttcc aatctggaaa aatccaagta gaagatgcta cgatcaatga ccatgacttt
    27301 ggtgaaaaag gtgtgctgac catgcgtcaa gctctttcat ggtcaagtaa cgtcgggatg
    27361 gtcatactgg aacagcgatt aggcggacga tggtataact atttacaaaa actgggattt
    27421 ggacaaagta ctcattctgg attagatgat gaagtaaacg gtgctttacc tacattaaat
    27481 attgtcgacc gagcaatgag tgcttatgga caagcggtag gtgtgacgaa tttccaaatg
    27541 atgaaagctt tcacttctat tgcgaataac ggtacaatga ttcaacctcg atatatcagc
    27601 aaagtggtgg atccccaaac tggagaagag cgaacaactc aaacagaagt tctagggcaa
    27661 cctttttcaa aagaaacaac agaaaaagtc cgtgaatata tgagagatgt tgtcgaaagc
    27721 gaaaactacg gtagtgctta tggtgtatat agtgtacctg gatacaatgt atcggcaaaa
    27781 aacggaacag cccaaatcgc ttctgataca gggggatatc aaacaggaga tacagcctac
    27841 ctgtattcga ttgtggagat ggttccttct gaagatccag actatgtctt gtatctaaca
    27901 atgaaacacc ctaagacata tgatcgaatg gcattggcta aaatcgcaaa tccattgatg
    27961 aaacgggcaa tggattttaa agaaactgaa gaagattcag atacagaaac aaaaacagaa
    28021 aaagtatccg tagccgatta tcgtaatctt gaagcggacg ttgcagcagc tgatgctcaa
    28081 aaaagtggac tgcaacctgt agtgatcggt aatggtaaaa aagtacaaaa acaatctact
    28141 gccaacggtg atcagttgat ctctggagaa aaactgatcc tatatactgg tggtgataag
    28201 ctgatgcctg acgtaacagg atggtcaaaa gcagatatca tgaagctggg gaaaatcctc
    28261 ggtattgaag ttagttttga tggagatggt tattgtgtca aacaagaact tgctccatat
    28321 gaaaaaatca ctgaagacaa acttagtttt actttagaag aataagaaga gaaataggag
    28381 agaaaagagc atggaatgga cacaagcatt gattcccatt gtcagcagtt gtgcaatgac
    28441 aattgccgca atgccgctat ttattggtta ttttcaaatg aaaaagcaag gtcaggcgat
    28501 tcgtgaggag ggaccaaagt ggcacaatag caaagccgga actcctacaa tgggcggctt
    28561 agtgtttctg atcggctcta ttttgacagg aatttgggtt ggagcttggc aaaaacagct
    28621 aactcctact cttttcatct tgctttttgt attagcgtta tacggagtaa tcggctttct
    28681 tgatgatttt ataaaaatat tcaagaaaag aaacatggga ctgaactcga agcagaaatt
    28741 gattggacag attctagggg gaatcatctt ttatcttgtt taccgttctg aaggttatcc
    28801 aggtgtattg aatttcttcg gactagatct acctttagga atcatttatg gtattttcgc
    28861 tctcttctgg cttgttggat tttcaaatgc agtaaatctg acagatggca tcgatggatt
    28921 agttgctggc ttaggaagta tctcttttgc agcttacggt ctaattgctt ggcatcagca
    28981 tcagtatgat gtattaatca tttgcttaag tgttttagga ggtttactgg gtttcttcgt
    29041 ctacaacaga aaacctgcca agatttttat gggagatgtc ggttcattag cgttgggcgg
    29101 acttttagcg gcaatttcta taatgctaaa ccaagaatgg acattgcttt tgattggttt
    29161 gatctatgtt atggaaacag caagtgtgat gcttcaagtt acttccttta agcttacagg
    29221 aaaacgaatt tttaaaatgt ctccaattca tcatcacttt gaaatgtgcg gatggtcgga
    29281 gtggaagatt gatacagttt tttggttgat cagcattgtg acttcgttga tcacattatg
    29341 gatcgtttgg taggagatga cgggaaatga aaaaaatatc aacatatgaa aataagaaag
    29401 tgcttgtctt aggactcgca aaaagcggag taagtgcggc caaattatta catgaattgg
    29461 gcgcacttgt caccgttaat gatggaaaac cttttgacga aaatccggaa gcacaagagc
    29521 tgctttcttt agggataaaa gtaataacag gtagtcatcc aatcgaattg ttggatgaag
    29581 aattttcatt gatggtcaaa aatccaggga ttccctacag tcatccttta gtagcaaaag
    29641 cccaagaaat gggtattccg gtaattacgg aagttgagct agcttacgaa gtagcggaat
    29701 gcccaattat tgggattaca ggaacgaacg gaaaaacaac gacaacaacg atgacaggac
    29761 tactactgaa tgcaggagca gatcaaggaa ttgcacgttt agcgggtaat attgggtatc
    29821 cagcaagtgg tgtagcgcaa gaagcaaaat cagaagataa aattgtgatg gaattgtcta
    29881 gcttccaact catgggaatc acagatttcc gccctcatat agcggtgatt accaatatct
    29941 atgaagcaca tattgattat catggtacaa gaaaagaata tgtcaaagct aaatggaacc
    30001 ttcaaaaaaa catgacagaa aaagattatc tgatccttaa ctggaatcag tcagaactac
    30061 aagaattagc gcaaagaaca aaagcacgcg tactgccttt ctcgacaaaa gaagtgttgg
    30121 aagacggtgt gtatgctgac gattactcaa tatactataa aaaagaaaaa ataatggaaa
    30181 tatctgaact tggcgtacca ggtaagcata atgtagaaaa tgcactagct gctatttctg
    30241 tagcaaaatt gtatggtata tcaaatgaag ctatacgaga aacgttgcat tttttccatg
    30301 gcgtaccaca tcgtacgcaa tatgtaggag aaatccaagg cagaaaattt tataatgatt
    30361 caaaagcaac caatatttta gcgactaaaa tggctctaag tggatttgaa acgtctaagg
    30421 tcgtgttatt ggctggcgga ttagacagag gaaatacatt tgatgaatta attccttcat
    30481 taaaaggaat caaagcaatg gtcgtatttg gccaaacaaa agaaaagttg atggatgctg
    30541 gaaaaaaagc aggcatcgag acaatagtaa cagccgattc tgtagaacaa gcagttcctt
    30601 tagcattaga aaacagtaca gatggtgatg tagttttatt atcaccagcg aatgccagct
    30661 gggatcaata cccaaatttt gaaactagag gaaacagatt catggaagct gtgaaccgat
    30721 taaaatagaa aaagtagaag cgagcgataa aaaatgaaaa ttttggttac aggcggagga
    30781 acagggggac atatttatcc agctcttgcc tttgtcaatt atgtaaagac tcaagaaccg
    30841 aatgctgaat tcatgtatgt gggagcaaaa cgaggtctag aaaacaaaat cgtccctgat
    30901 acaggaatgc ctttccatac cttggagatt caaggattta aacgaaaaat ttccatgcat
    30961 aacatcaaga cggtccgatt gtttcttaag agtatccgtc aagcaaaaaa aatcctcagt
    31021 gattttcaac cagatatcgt tatcggtact ggaggatatg tttccggagc ggtagtgtac
    31081 gctgcagcca aaatgggtat tccaacagtt atccatgaac aaaacagtgt accaggtgtt
    31141 accaataaat ttttaagccg atatgtggat cggatcgctc tttcatttaa agatgcggct
    31201 tccttttttc ctgaaaacaa agcagttctt gtaggtaatc ctcgagcaca agaagtagca
    31261 gatactaaaa aatcagatat tttgaaaaca tttgatttgg atccagaaaa gaaaacagtc
    31321 ttgatttttg gcggtagtca aggagcactt aaaatcaatc aagcagtatc agttttttta
    31381 agtgaatata ttccttcttc ttaccaagtt ttgtatgctt caggagatag atattatgaa
    31441 gagatcctaa ataaaataaa tcctgaaata caaaatatta gtgtccagcc ttatatcaaa
    31501 aatatggcag aggtcatggc ttccagtgat ctgctggtgg ggcgtgctgg tgcaacttcg
    31561 atcgcagaat tcacagctct ggggttaccg gcagtgttgg ttcccagccc atatgttacg
    31621 aatgatcatc agactaaaaa tgcaatgagt cttgttcacg caggagcagc aaaaatgatt
    31681 gcagataatg aactaacagg tgaatcacta agtcagacag tcaacgaaat catgggtgat
    31741 gaagaattgc aaaagcaaat gtgccgagct tctaaagaac aaggaatccc tgatgcttca
    31801 aaacgtcttt atgacttagt aaaacaaata atcaaaaaat aaaggcggtg gtcttagtga
    31861 gtaagaaaaa agaaccaaaa aaattgtctc atccgtcttc tgatgaaaac aatttgactc
    31921 cttggcaaaa ggctaaccga aaatatctgg cagaacaaga gatgaaaaac caagagccaa
    31981 aaaaagaaga cataacatta gatacacccc tttcagattc tgaagaagaa aaaacggttc
    32041 aagaggaaca gcaagaagaa agccagtccg agaaaaaaat cgaatttttt gaagagatca
    32101 agcaaaagaa aaacggtgga ccatataacg gttctttttt gaaccggctg cccaatttaa
    32161 aaagtcaacg gcacaaagta ctatttcgtc ggttagcttt gatcatcact gtattgggta
    32221 taccgctgat ttttttgatc tattatgttt ctccttatag caaattacaa gcagttgcag
    32281 tatcaggcaa taagacagtc aacagccaag aaatcatctc tgatacaaaa ttgtcattag
    32341 gagaaaatgt ttggggacag tattttcatc gatctactta tatcgatcgc cttaaaaaag
    32401 cacagccaag aatcgaaaca gcaaatatac atttcaaagg gatgaatgaa ttcgatttgg
    32461 atgtaacaga atataaagag attgctttga tcgcaaaaaa caatcaatac tacccagtga
    32521 ttgaaaatgg aacagtatta gatgaaaaag tagcaaatcc tacaaaaaat ctccctatct
    32581 tggaagagtt caaagactct gcaaaaatca aagaattaac aaagcaatac aatcagttat
    32641 catcagaatt acaaaaagca atttctgaaa tcaagtacac gccaagagca agcaataaaa
    32701 atctgatcca attgaatatg aatgacggca atcaagttat tgtaaatatc aataatcttg
    32761 cgaaccaaat gaaatattat tcgcaagtag ccaaagatat ggatgaaaaa ggtgtgatcg
    32821 acatggaagt tggtatcttc tcgcatcctt acggtagcac tcaagaaacg gaagaatcgg
    32881 gccaatcgga agaaacaact gaaagtgaag aaaatgcgga tcaaacaaac gaatcaagtg
    32941 aagaggcaga aacgcaaaaa gcacaaacac ctggatcgtc tagcacaaac ggatcatctg
    33001 attcaaatga ttcaagtgaa acaagtcaaa tagaagataa tccaagtaca actccgtcaa
    33061 gtttaaatga aaattgataa aacaacttta aaaagtaaga atgtactttc taaaaaccag
    33121 taatttatgg tagaattgga agcagtgaat atatctatta ataagtatat tttaaaacgg
    33181 acgctagttg ttcgcttgta tatggaatag taagtaggag ggaatcccat tcatggcaaa
    33241 aacaggaatg tatgtaggcc ttgatattgg aacgacatct gttaaagttg tcgtggctga
    33301 atatatcgac agccaaatga atattattgg agtaggaaac gcaaaatcag aagggattaa
    33361 ccgaggcatt atcgttgata tcgataaaac ggtccaagcg atacaacgag cagtacgaca
    33421 agcagaagaa aaagcaggta tccagatcaa aggcgtaagt gtcggtttgc cagcaaacat
    33481 gcttgaagta gaaaattgcc agggaatgat tgcagttaac ggagattcaa aggaaatcac
    33541 cgatgaagat gtcagaaatg tggcttcagc tgcccttgtt cgttcaatac ctcctgaacg
    33601 tcaaatcgtg tcaatattgc cacaagattt tactgtcgat gggttcgagg gaatcaaaga
    33661 tcctcgtgga atgatcggcg taagattaga aatgtacggt ctgttgttta caggacctaa
    33721 aacgatcatc cataacatac gtaaatgcgt ggaaaatgcc ggattaatcg tcaacgaaat
    33781 ggtgattact cctttagcgc tgactgaatc aattctttct gacggagaaa aagattttgg
    33841 tacgatcgtc attgatatgg gtggcggcca aacaacaacg gctgttatgc atgataagca
    33901 attgaagttt accaatcttg accaagaagg tggcgaattt gtcactaaag atatctctat
    33961 tgtattaaat acgtcattta acaatgcaga agcgttgaaa ataaactacg gggatgcata
    34021 cccagaacgg acatcaccag atgaagaatt tccagtagat gtgattggtc agtcagaacc
    34081 agtgaaagtc gatgaacgct acttgtcaga aattatttca gctcgaatgg aacagatttt
    34141 caacaaagca aaagatgcat tggaccaaat cgaagcatta gagttgccag gtggcgtcgt
    34201 attgacaggc ggagctgcta gtcttcctgg tgttgtggac ttggcacaag aaatcttcgg
    34261 cgtaaatgta aaattgtatg ttccaaatca catggggctg agaaacccgg tatttacaaa
    34321 tgtaataagt atcgtggatt attcagcaaa cttgagtgaa gtgtatcaat tggcaaaaat
    34381 tgctgttacg ggtgaaacct cagcagctcg tcaaatggta gttgaacaag aaacaacaaa
    34441 cacatatgag agctatgaag cacctgaaga aacaatctac gatgagccgg aaccaaaaga
    34501 gtccggagaa aatgtaaaaa ataaaatcaa gggtttcttt acaaatattt ttgattaatt
    34561 catcctggga ggaataagat atggaattct caattgataa taatatcaat gacggcgcag
    34621 taatcaaagt catcggagtc ggtggtggcg gtggaaatgc tgtaaaccga atgattgaag
    34681 aaaacgttaa aggtgttgaa ttcattacag ccaacacaga cgtgcaagca ttaaaaaatt
    34741 caaaagctga aacagttatc caattaggcc ccaaatatac tcgtggttta ggtgctggtt
    34801 ctcagccaga agttggacaa aaagcggcag aagaaagtga acaatcctta cgcgaagctt
    34861 tagacggtgc agatatgatt ttcatcactg caggaatggg tggaggaacc ggtacaggtg
    34921 ctgcaccaat cgttgcaggt atcgcgaaag aattgggcgc attgactgtt ggtgtcgtga
    34981 cacgtccatt cacttttgaa ggaccgaaac gtggccgttt tgctgcagaa ggtatcgctc
    35041 gtttgaaaga aaatgtggat acattattaa ttatctcaaa taaccgttta ttagaagttg
    35101 tagataaaaa gacaccgatg cttgaagctt tccgtgaagc agataatgtt ttacgacaag
    35161 gtgtacaagg tatctctgat ttgatcacag cgccaggtta cgttaacctt gactttgctg
    35221 acgtgaaaac agtgatggaa aaccaaggta cagcattgat ggggatcggt gtggctagtg
    35281 gagaagatcg cgtagtagaa gcaacgaaaa aagcaatctc ctctccattg cttgaaacat
    35341 ctattgatgg agctgaacaa gtacttctta acatcacagg cggtttggat atgacattgt
    35401 tcgaagcaca agatgcttca gatatcgtag caaatgcagc aactggcgat gtaaatatca
    35461 ttctaggtac atctatcaat gaagaaatgg gcgatgaaat ccgtgtgacg gtcatcgcaa
    35521 caggtatcga tgaatcaaaa aaggaacgca agtctagccg accagctaga caagcacaaa
    35581 tgcaatcacc tgctcaaaag actgtattag atatggatca agctaaacca acttcttcag
    35641 aagaagaaaa cagttttggc gattgggata tcagacgtga acaaaatgtt cgtcctagag
    35701 ttgatgattc caattttgac aatatcgaaa aaaaagaatt tgatacattc aaccgcgaag
    35761 aaacaaaatc tcatggcgat gatgaattaa atacgccacc gtttttccgt cgtaaaaaat
    35821 aaaggagagg aagagcacat gattgctgac aacttgcaga aaatcaagca agaaattcag
    35881 gattcgtgtg ctcttgttca tcgtgatccg aaagaagtta cattagtagc tgtaacaaaa
    35941 tctgttgaat ccgctcaagc tgaagaattg gttagagctg gcgttatgaa ttgtgcagaa
    36001 aaccgagtag ataaattatt agaaaagaaa caagatttat ttgattttcc tgaaataaag
    36061 tggcatttaa ttggtaattt acagcgcaga aaggtaaaat tgattgtaaa tgaaattgat
    36121 tactttcatg cgttggacag tttaagatta gcagaagaaa tccagaagcg gttagagaaa
    36181 gaattatcct gttttattga agtaaatgtt tctggtgagg aatcaaaaca tggaatttca
    36241 ccagatgagc ttttaccgtt tgtggaatct ttagctgcct gcacaaaaat caaggttgtt
    36301 gggttgatga ctatggcgcc taaagaagct tctgatgagc aaatccataa agtgtttggt
    36361 acgctgaaag aattgcgtga tcttgttcaa gcaaaaggtt atgcccatgc accatgtagt
    36421 gaattaagta tggggatgag tcaagacttt caaattgcga ttgaagaagg tgcaacattt
    36481 atccgtgtag gaacagcgct attcaaagac gaataaagga ggaacaaaaa tgccgctttt
    36541 aaacagagga gcaattgcta attttttcgg attagctgat gaggaagagt acgaatacca
    36601 agattatcct gaaacaacaa aaaaggctgt acagccaact aaaaaaaata caacacagaa
    36661 tcaatcaact cattctgtat ctgctgcgaa tactcatgaa aaacaaaaaa cggcgacttc
    36721 acgtcctgta acgcatgaaa gtattcagcc ggctgaaaag aaaaaagtaa ttgaactaca
    36781 tcaatcacct acaaaaactg tagcgaaaga aagaacagct tcaagaacct ctacacaacc
    36841 taaagcaaat cttgctggaa aaatcactgt aatggaacca agagcttatt ctgaagctat
    36901 ggcgattgct aaacgaatca ttgctggaga agcaacctta gtgaattttc atttagtaga
    36961 agaaaaacaa gcgagaagaa tcgttgattt tctaacagga acagtttatg cactagatgg
    37021 agatatcaaa cgtgttggag atgagatttt tctttgtaca ccgactggga tggagattga
    37081 cagttcaacc gctcaatctt ttgcagatgc gaatttgttt gatctgtaag aggaggaact
    37141 acgatttata ctattgcact attacttcat ttacttcaac gggcagccta tttctatagc
    37201 attatcttga tggtatatgc attgctctct tggtttccag gcgggtatca atcagggcta
    37261 ggacgattat tagctaagat ctgcgaaccg tatatcagtt tgttcgatcg tctgcctttg
    37321 aggattggac ccttggattt cacaatttta ggggcaatcc tgatcttgaa cttagccgta
    37381 caaggtttag cacagatcgt tatatggata actgtccatt tagtttattg attgaagcaa
    37441 caaaatcttt attctcagaa tagataggag gggaaaattt tggatgcaaa tgtataccag
    37501 cactttcggg cagatgaacg tacatttatc gattcggtag gcgattggat tgaacaggtt
    37561 caaggacaat atgcacccta tctgaccgaa tttcttgacc caagacaatc ctatatttta
    37621 gaaacactga ttcgacaaag cagtgatttg cgtttcatgt tttatggcgg atatgaacag
    37681 gcagaaagaa aaagatgttt gattttcccc gattattacg aacctgtaga ggaagatttt
    37741 gaaacagcat tgtatgaaat ccattatcct agcaaatttg ccagcctaag tcatgggaaa
    37801 atccttggaa ctttagtggg aacggggatc aaacgctctt actttggcga tatcatctcg
    37861 gacggtgatc gctggcaagt atttattgca aatgaggtgg atcattttgt tgctgcacaa
    37921 gtaacaaaga ttggaaaggt tgctgtacgc ttggaaccaa tcaaatacac agaaatgatt
    37981 atgccgaaag atagctggac acaagaaaga ggaacagtta gttccatgcg actagacagt
    38041 gtgatctctg agatttataa tatttccaga cagcggtcca agcagctgat cgaagctggt
    38101 aaagtaaaag tgaactggac agaaaataca agacctgatt ttgtacttga actattagat
    38161 attatttcag tcagaggtta tggcagagtc cagatccaag aacttgaggg gaagacgaaa
    38221 aaagaaaagt acagggtact gttcggtgta ttacgtaaat aaaataaaaa ggtggtttac
    38281 tcatggcttt aactccatta gatatccaaa ataagacatt cccgacaaaa atgcggggat
    38341 ataatcaaga cgaagtagat gatttcttag atttagttgt tcgtgactat gaggaattga
    38401 ctcaaagaaa tcgagaatta gaaaaagcag tcaaacattc tgaagaaaaa cttgagtact
    38461 tcaatgaatt aaaagatgct ttgaaccaat caatcatcgt agctcaagat acggctgata
    38521 aagtaaaaac aagtgcaagc aaggaatccg aagtgatcgt tacttctgca caaaacaaag
    38581 cagatgagtt agttgcgaac gctgaaaaac gtgcacatca attaacaact gatgcagaag
    38641 aaaaagcaag aaaaatcttg acagatgcaa cagaaaaagc aagacagctt gcgacagaaa
    38701 ctgaagatct taagaaaaaa acacgagtat tccatcaacg tatcagcttg atgcttgagt
    38761 ctcaattaga acaagtgaaa agtccggaat gggatgaaat tttacaacca ttctccagct
    38821 acgtgactga cagccatgaa gtgatcaaag aagttttagc aaaacagctt gacaatgaaa
    38881 atgatactga tgtaaactca gacacaggag tcatagaagc acctatgacg gcatttgata
    38941 cacaggctat tgatatctcg atcgtgcctg gtgaaaatga aaacgagtag aacagaaaag
    39001 cactttgtta ttcttaaagc gagccgatga gagtggaagt tcggtaagac actgcatggt
    39061 gaaagatcct ctacttgaga cctgcttttc cgaaattaga gtaagaagca gcggctgacc
    39121 tcgttattgg tcacagagag tttgcactag atagatgcaa ctaaatttgg gtggtaccac
    39181 ggcatgttcg tcccttgcgg ctgaacatgc ttttttgtgt ccggaaaaca aataaaggag
    39241 tgtatggttg aatgaaaatg aaagaaacct tgcaattagg aaaaacaaaa ttccctatgc
    39301 gtggtaattt gccaaaccga gaaggcgagt ggcaaaaaga atgggaagaa aatcgaatct
    39361 accaaaaaag acaagagttg aacgaaggaa aacctagctt tgttcttcat gatggacctc
    39421 catatgccaa tggtaatatc catttaggac attcattgaa taaaatcagt aaagacatta
    39481 tcattcgttc aaaatcaatg tctggctatc gtgcaccata tgttccagga tgggatacac
    39541 atggattgcc gattgaacaa gtattggcta ataaaggcgt gaaacgtaaa gaaatgtcca
    39601 tggcagaata cttggaaaaa tgtcgtgaat atgcactttc ccaagtagat aagcaacgag
    39661 cagatttcaa acgcctagga gttgcaggag attgggaaca tccttatgtt acattagatc
    39721 cttcttatga agctgcacaa gtacgcgtat ttggtaaaat ggctgaaaaa ggctatattt
    39781 acaaaggatt gaaaccaatt tactggtctc cgtcaagtga gtcttcttta gcggaagctg
    39841 aaattgaata taaagatgta aaatctccat ctatttttgt agctttcaat gtcaaagacg
    39901 gcaaagatat tcttgatgaa gatacagctt ttgtcatttg gacgacaaca ccatggacat
    39961 tgccagcaaa ccaaggtatt gctgtaaatc caaaatttac gtatgtattg gtggaagccg
    40021 atggccgtaa gtttgtcgta gcgaaagatt tgctagaaac agtccaatca gaaatcggtt
    40081 gggaaaatgt aacagttcta aaagaatttg ctggacaaga aatggaatat atgactgcaa
    40141 gtcatccatt ctatgaacgt gaatcacttg tgattttagg cgatcatgtt actttagacg
    40201 ctggtactgg attagtccat actgctccag gacatgggga agatgactat atcgctggta
    40261 gcaaatataa actatctgta gtgtcacctg tagactcaaa aggattgttt acagaagaag
    40321 cacctggatt tgaaggtatc ttttatgaca aagcaaatcc tatgatcact gatctattaa
    40381 aagaaaaagg agctttgctg aagctagatt tctttactca tagttatcct cacgattggc
    40441 ggacgaaaaa gcctgtgatc tatcgggcaa ctccacaatg gtttgcatct atcgataaat
    40501 tccgtcagaa tattttggat gaagtagaaa aagtagagtg ggttatccca tggggtaaaa
    40561 cacgtttgta taatatgatc cgtgaccgcg gcgattgggt aatttcccgt cagcgtgcat
    40621 ggggagtacc acttccgatt ttctatgctg aaaatggaga agcaatcatc acaccagaaa
    40681 caatcgaaca tgtggcaaaa ttatttgctg aacatggatc aattatctgg tttgaaaaag
    40741 aagcgaaaga acttcttcct gaaggattta cccacccagg ttctcctaat ggcgaattta
    40801 caaaagaaaa agatatcatg gatgtctggt ttgattctgg ttcttctcat gaagctgttt
    40861 tacgtcagcg accagaatta tcattcccag cagatatgta tttagaagga tcagaccaat
    40921 atcgtggctg gttcaactca agtatcacga ctagtgtggc tatcaatggt gtagcaccat
    40981 acaaatcagt tatttctcaa ggatttgctt tagatggtga aggccgtaag atgagtaaat
    41041 ctttaggaaa catcattgca ccagaaaaag tgatcaaaca atttggtgca gatatccttc
    41101 gcttatgggt atctagtgta gattatgaag cagatgttcg tgtttctatg gatatcttaa
    41161 gtcaagtggc agaagtatat cgtaaaatca gaaatacgat gcgtttctta ttagcgaata
    41221 cagaagattt cgatcctaaa aaagatactg tttcgtacaa tgatttacgt tctgtagaca
    41281 aatatatgac cgttcgattg aaccaagtaa tcaaagaaat ccgagaagaa gggtacgaca
    41341 aatataactt catgcatatt taccgtacag ttatgaactt cttgacggtt gatctatcgt
    41401 cattctacct ggattttgct aaagatgtag tttatattga agcagaagat gattatcaac
    41461 gtcgttgcat gcaaactgtt ttctatcaaa cagctgtagc tttgacaaaa ttattgactc
    41521 ctatcattcc gcatacagca gaagaaatct ggtcattcct gaaagaagaa gaggagtacg
    41581 ttcagttaag cgagtttcct ggttatgaag agtttgcaaa ccaagaagaa ttgatggata
    41641 cctggactgc tttcatggac ttccgtgata atgtcttaaa agcattggaa gaagcaagaa
    41701 acagcaaatt gattggtaaa tctttggaag caaaactaac tgtttatcca aaacaacaag
    41761 ttcgtgaaat gttaaaagct ttggatgcag atattgcaca attattgatc gtttcaccag
    41821 actactttga agttatggca gcagatgaac aagtgccaga taacgctatg gtatttgatg
    41881 atgttgctat tacagtggaa aaagcagacg gggaaacttg cgatcgctgt cgccaagttc
    41941 gtaaagatgt aggagtagat gaaaaacttc ctcatctatg cggtcgttgt gcaaaaatcg
    42001 ttgaagactt ctatcctgaa gctgtagctg aaggattcga agaaaagtaa aagggaaaag
    42061 ggggtgtgac atgttctttg tcacaccccc ttttgttatc aatcgtttaa ttttccacgt
    42121 tcacgatacc agttatctgg ttgccagatc cattcgaatc cgtctttttc aagtagttcg
    42181 aaagctgctt taggtcccat tgatccagct ttgtagttgg gaaaatccgg ttgtgtttgg
    42241 tcccaagctt ttcgaatgac atccacgata tgccaagatt gagcgacttc ttcccaatga
    42301 gagaagttcg ttccatcacc attcaacgca tctaatagta atttttcgta agcttctggg
    42361 ctattttcaa ccatttctgc actatttcta aattccaatt tgattggttc cgtttcaaat
    42421 ccttgcccta cttctttccc attcaaggat aaagaaaatc cttcagttgg ctgaatatag
    42481 atcgttagaa cattaggtgg aagtgtcgta tcgtcacatg gttcatcgac agatgttttg
    42541 aatacattaa caggaacttg tttgaatacg atgttgatcc gagtcccttt ttcagtcaaa
    42601 cgtttgcctg tacgtacata gaaaggaaca cctgaccaac ggaagttatc gatagtgaat
    42661 ttgcctgcga cgaatgtttc agtctctgat tgagcatcca ctttgtcttc ttcgcgatag
    42721 cccttgaatt gtacaccatc caattcacct tgagcatatt gcccgcgaac gaagttttct
    42781 aacacttctt cttcgttata aatgcggata gctttcaatg ctttgatctt ttctgtacgg
    42841 atttcttttt cggaaaatgc tactggcggt tccattgcaa gtaatgctac aacctgtaaa
    42901 atatgatttt gcaccatgtc tttaagtgcg ccactatgat cgtagtagcc cccgcgatct
    42961 tctacaccga ggttttcgcc aaaagtaatt tggatattgt cgatatagcg attgttccat
    43021 tgagcctcaa aaatattatt ggcaaaacgg atagctgaga tgttttggat catttctttt
    43081 cctaaataat gatcaatcct gaaaatatct tgttctggga atacttctct gatttgctgg
    43141 ttcaattcaa aagcagactg gtaatcagaa ccgaacggtt tttctatgat caaacgattg
    43201 aagccatttt ttgtcataat attttgtgat ttcaaatgag aaacgatcgt tccaaaaaat
    43261 tgaggtgcca tagccaaata atagacacgg ttaccgttta attgatagtg tccatctaat
    43321 cggtcagaca attcttttaa tgtctgataa tgcgttgaat catttacatc atgggattga
    43381 tagtaaaaat ggcttgcaaa ggtagttgct tcttcatctg aaggattcaa tgcacggatt
    43441 gtttctttga caacttcacg gtagtgctca tcgctccagg gacggcgagc ggttccgatt
    43501 acagcaaaat gctcgcctaa atttcctttt ctgtaaaggc ggaacaaaga cgggtacaat
    43561 ttacgctggg ctaggtcacc tgtaccgccg aatatcgtaa acaatacatt tttttcatta
    43621 gacatgtgga tacactcctt tatattttat cgacaaaaat cgtgctggcc gccttaaagc
    43681 tgacggggat tttctttcta tcattttgga tagtgatcgg tccttcataa gctgcgatgt
    43741 caacgatctc atattcttcg ttgatattca ggtcaatagt gactaagtaa tccaacaatt
    43801 ctttttcatc aagcactcgt gcgatacgca cttttgtacc gacaggatag gactccaatg
    43861 tttgtcggcg ttcttcatgg acaacttcct cttttttagg aatcgatcct ccatgaggac
    43921 aatgttcagg atgattcaaa tagttttcta aatgatctgc aagatgttcc gaagtcacat
    43981 gttccaatac ttcagcatca tcatggactt cattccagct atagtctaaa tgttcaacta
    44041 aaaaaacttc ccataagcga tgtttgcgaa tcagactgct agctttttgc agtccgcttg
    44101 cagtcaattg tacaccttga taaggggaat gttctacaag ctcttctttc acaagtttag
    44161 aaatcatttc actgacagat gcagctgaga catctagact agatacgatt tgtttattgt
    44221 tgactttcgt tgtatctcca cctagttcta aaatgatttt caaataatct tctcgatttg
    44281 gtgtcatatt cgatcatcct ttcatggtaa aaaaccatca ttagtaagtg taacaaaaaa
    44341 aacgttaatt gactattttt ctaaataaaa aacaaaggat ttttagacgt ttttacaaca
    44401 aaaaacgaaa gatgatagag aagactcatt ctttcgttta taaaggatat atatatacat
    44461 tgggagggat ctatttttca gataacaact tatatgaagt gtctgcagat tcgtcataaa
    44521 gagtttgttc gggataagaa aagataagat aaaaaccata ctgatcacgt acgactaaac
    44581 gatattcatc tatttctacc acagatgtgc caagagactg accgttgatc aaaaacgtgt
    44641 aatcagatgt aatctgtaat tgttgttttt gctggctatc actaaagaac catgtacctt
    44701 gatactttga gagtccttct gacttttccg cttgtttttt ctttttcaag taaataaaac
    44761 ttgagagaac ggtaatgagt gaaccaagaa aatagatcat tttttttatc accaaatcac
    44821 tcctttatga gaaaataatc gcatagacat attctttctt ctttatttca ttgtaccgaa
    44881 taaaagctaa aatttctcta agactttcga ctggtttttt tactgttttt ctacaaatta
    44941 tgataggata catagtagga agaaaggtga cataatttga agtatcagca agtggaaata
    45001 gcttttttta ttgaccgccc gaatcggttt atagcacatt gtatgaaaaa agacggagaa
    45061 ataattattg cgcatgtcaa aaatacaggt agaggaaaag aggtcctgat accaggcgct
    45121 gaagtggcta ttgtatttgc tcctggacct aaacggaaaa ccgcctatga tctgattgct
    45181 gtaaaaaaga agggtgactg gtttaatatc gatagtcaat tgcctaatcg gctggcaatt
    45241 gatggtattt tagacggcac gatcctttta ccaggattaa ctggtccatt tacggtatac
    45301 aagcgtgaag taacttatct tcactccaaa tttgatattt atttagagac ggtggtcgga
    45361 caaaaagcat ttgttgaagt caaaggtatg acacttgaaa ataaagcgat tggtgctttt
    45421 cctgatgcgc ccacactcag aggattgaaa catataggag aattaacgta tgccgcacaa
    45481 gatggttatg ccgcttatgt cttgtttatt gctcagttcg aacatcttca tctggcaacg
    45541 atccatgaag aaatgcaacc agcactagct gatatggttc gacatgcgca gcaaagcgga
    45601 gttcaaatcc tcgcctataa ttgtcaagta tcggcagatg aggtaactgt caagcaggcc
    45661 attccatttg atgtagatat cccttttgaa gatcctatac aatagaaaga aggtaaaata
    45721 atgatcaact taggtattat cggaacaaat tggattactc atcaatttgt ccaagcagct
    45781 ttaagcacaa aaaaatatga attgacagcg gtatattcta gacatttgga aaaagcacag
    45841 gaatttggtt ctcattatga aggggatatc gaattcgcaa cagatttgaa gacttttttc
    45901 aatattactc atatggacac catttatatt gcttctccga atagtcttca ctttagtcaa
    45961 gctaagcaag caattttggc aggaaaaaat gtgatagttg aaaagccagc tttttcgacg
    46021 ccaaaagaaa tggatgaaat catccatttg gcaaatgaac acaatgtgta tttttttgaa
    46081 gcagcaagaa atatccatga atcaggtttt aaaaagattg ccgattactt accattaaaa
    46141 gacgagataa tcggtgcaaa tttcagctat atgaaatatt cttcgcgcta tgaccaagta
    46201 ttagatggag aagaaccgaa tatcttctcg actcatttct caggtggtgc attgatggat
    46261 ttaggtgttt accttgtata tgcagctgtt gcttggtttg gaatgccaaa agaagtccat
    46321 tatttcccaa gaaagatttc tactggtgta gatggtcttg gatgggggat cttacgttat
    46381 gagaattttg atgtatcgat ccagccaggt aaaatcggtg attcttattt accgtcagag
    46441 atttattttg actcaggaac gctagtgatg aatggagtca atgcaattga acaagcacaa
    46501 tttcatgatc gcgcgcataa agaaatcatt gatttggcgg taacagctgc agaaaatcca
    46561 atggcagatg aagcagagga ttttgccaat gtcatggctc atccgaaaga tccagcttgg
    46621 ggattgttgt atgaagagtg gatcgagcta gctagaaatg tgaaccaagt gatttatgat
    46681 ttaagaaaaa atggcggcat caaattcgat gcagataatg aggaagattt ttaatgaacg
    46741 aatttgtaca agtatttccc gaaaattggc agaaaaaata tgaggataaa gggtttatct
    46801 caccttctct tattcaacga gcagtttttc agccactaag taataaacaa agtatagtag
    46861 cggtttctcc tacaggttca ggtaaaacac tggcttatct ttggcctcta ctactaaacg
    46921 tggaaccagg tgaagcaagt gcgttggtca tttttgcttc ttctcaagaa ctagctattc
    46981 aagtagcaga tgttgcacgt gaatggggaa aagacaaaga gttgaaagtc caatctttgg
    47041 tgggcggagc caacgtcaaa cgtcagattg agggtttgaa ggaaaaacca gaaatcttga
    47101 ttggtacacc aggaagaata ttggaattga tgaaagcaaa aaaaataaaa gcacatcaag
    47161 tgaaaacaat ggtatttgat gaagcagacc agctatttga cgctgggaac agccaaatca
    47221 ttgatcaaat tcttcatcaa gctccaacag agtatcagct agcttttttt tcagcgacag
    47281 cagatcgttc ccttgaaagc attgaaaaaa tcactgggaa aacgtttgag acaattgacg
    47341 tgacagcaga ggacgattct cgaaaaggac tgagacatta ctttttacgt gtaccgatac
    47401 gaaagaaaga tgactacttg agacgtctca cgcatataga agattttcat ggtctgattt
    47461 tctttaatca actgactgaa ttaggcgtaa tggaagaaaa attgctgtat agaggtgtac
    47521 cggtaggaag tctggcctct gatcagaaca agctactccg aaaagcagcg ctagaacaat
    47581 tcaaaaagaa aatggtcaga gcacttttga ccacagatgt ggcggctaga ggtttagata
    47641 ttacaggtct tccttatgta gtgaatgcag aagttccgtt aagtgaagaa gcttatttgc
    47701 atcgttcggg aagaactggt cgaatgggta atgaaggaat agtaattaca ctcgtacaag
    47761 ataataatct aagagattta aaacggcttt tacgtccatc aaatataaca cttgaagaga
    47821 tttttttata cggaggtaag ctgcaaactg agcagccaac caaagaagat gcagctcctg
    47881 cagtaaataa aaagtatgcg aaaacttttt ctggaaagga gcagaaccca gaatataaca
    47941 aagaaaaaat aagaaaaaaa gttaaaaata aatcaaaaaa agagagaaat aaaggagcaa
    48001 ggcgcaaata agcgcctttt tatgctatga ttatgaaaac gggaacaaaa ttggttgcca
    48061 gaggaggggt tatgtgaaag aacgtcaaga agagatcttg cagctattga cagaaaacca
    48121 acaaggattg acagcaagtg atgtagctga gcgcttaact atcgatcgaa gcaatgcaag
    48181 ccgatattta agtgaactat acaaggccca tcatattgta aaaaccgctg gccgaccagt
    48241 cgtttactct ttgccaacgg aaaagtcaaa atctgatgaa gtgcatgtcg actcttctac
    48301 gcaagtgact tttgaaacac tcgttggaga aaatgattct ttaaaagtca gcatacagca
    48361 ggcaaaagct gcgattcttt atccaccgcg ggggttgcat acgattattt ttggagaaac
    48421 tggtacaggg aagtcgatgt ttgctgaatg tatgtatcat tttgcaatcg attcagagat
    48481 gctttctgca gatgcgccat ttgtttcttt caattgtgcg gattatgctc aaaatccgca
    48541 actgctcttt ggacacatct ttgggatcaa aaaaggggct tacacaggag cagctcaaga
    48601 tagtcccggt ctaatagcca aagcagacgg cggtatattg tttttagatg agatccaccg
    48661 tttaccgccg gaagggcagg aaatgctgtt tactttcatt gataaaggta tttaccgtcc
    48721 gcttggagaa agtgcacaag tacatgaagc atctgttcag atcattgggg cgacgactga
    48781 atcttcagaa agtttcttat ctacgttcaa tcgacggatt cctatggcaa tcaccttgcc
    48841 gaatcttgct tcacgttcac tggatgagcg ttatgaaatc atctctcttt ttatcaaaca
    48901 agaagcgaat cgtttgaatc aacgtatcga tatcgaaaaa gaagcgattc ttgccttcat
    48961 gctttatgat gcggaaggaa atatcggtca agtgaaacga gacttgaaac tagtctgtgc
    49021 aaaatctttt ttacattacc gtactcatca tgagaaaaag ctaatcattc gaaaagaaga
    49081 actttccctt caagtacaaa aaggattact gaaaatcaag gaaataccgg aacgtctcga
    49141 ccgattcatg gacagcaaaa gtcagtattt gacatttgaa ccaggatttg ctgatgttgt
    49201 ctggtcacaa gatccagaac gaaacatgca ggtctataac gatattgagg aaaaagtcac
    49261 ttctctttcc gaaaccggtg tggagaacat tgatctagag accctcattt caaaagatgt
    49321 ggatgcttat ttccagacat atgtcaaaga attgactaaa agttcgattc ccaaagatct
    49381 tttgccagat gaaatctggc ggttaaccaa tcaattgtat gatgtggctg aaaaacggtt
    49441 agaccgtatt tataatgaaa aagctcgttt tgcttttgct ttgcatctgc aaagtacatt
    49501 ggatcgtgtg agagaaggtc atatgatcgt ccacccagat ttgaataacg tacggaaaaa
    49561 ttttaagagg gaattccagg tagcaatcga tctttcaacg atcattgaag aagaagaaca
    49621 agttgagatt ccttttgatg aaatcggctt tattagtatg tttctttcta tcaatctagg
    49681 agaaagtgag cctgttaaag aaaacaaagt agatgttctc atattgatgc acggcagaca
    49741 gactgcttca agcatgttgg agatggcaca agaactatta ggaacaaaag tagggaaagc
    49801 ttttaatatg ccactggtta tggaagttca aacaatgtat gaagaagtgt tacaatatgt
    49861 caaaaactat caagagcatt tgacgaatgg cctactcttg ttaacagata tgggatcatt
    49921 aaacaccttc agtgatttga tttatgaaga gactggcatt cggacgaaag ctatcacgat
    49981 gacaagtacc atgattgtga tagaagcgat acggatggca agtgttggaa gaagcttaga
    50041 agatatttat caaaatatcc agctttcctt tgaatcgatc gtacgtgatc agttcaaagc
    50101 ggaaaagtct gaaactttac agcgtaaaaa agccgtaatc gtgacatgct ttactggtga
    50161 aggagtagct gccaaattat atcagcgtat tatgccagtg attaatcaaa ataaggtaga
    50221 actgatccag atgcagtttt tagaacgtga atcattcaaa aaacacatcg atgccttatt
    50281 ggaagaatat gagatcaaag caattgcggg aacagttgat gttgattatc aaaatatccc
    50341 atttttttca gcctatgacg tttttgatga tgaaaaacta aatattttaa agcgtatagc
    50401 tgatgatgag atcccgacag ctaaaattgt cgattcactt gctggatcat taagcgatgt
    50461 cttttctatt gatgaactga tccgttcatt gcaaaagaca gttcagcaga tccagaccga
    50521 tttgtcgatt atcgtggaac ctggagtaga tactggaatc gttatccatt tagccttcat
    50581 gttagacgga ttgatcaaac aagaaagcca tcggcaattt gagaaactgt ctattttctc
    50641 aaaaatttat cgtttggaaa tggatatcgt tcgggcaaac ttgatggcac tagaacgaaa
    50701 atatcaggta aaaattccag aagatgatat cgcatttctt acacaaatgt ttcttgaaaa
    50761 taaaataaaa aaatgaacac actaatcata ctgtttacac actaaacatc tgtgtgcgca
    50821 ctataaaaaa gagctaaaaa gcatgaaaac gctatttcag ctcttttttt tattggcatg
    50881 cttcttgcgt tatataaaag tgtaaaaaaa taaaaggagt gttaaaaatg gcaaaaaaaa
    50941 caatcatgtt agtttgttca gcagggatga gtacgagttt attggtcaca aaaatgcaaa
    51001 aagcagcaga agaaaaaggg atggaagccg atatttttgc ggtctctgcc tcagatgcag
    51061 ataataattt agaatctaag aatgtcgatg tattattatt aggtcctcaa gtacgtttca
    51121 tgaaagctca atttgaacaa aaacttgcgc ctaaaggtat tccattagat gtcatcaata
    51181 tgcaagacta tggcatgatg aacggagaaa aagttcttgc acaagcagaa aatctaatga
    51241 aataaatcaa gtatgcagtt gggggtataa caacgtggaa gatcaacaaa atctagaagc
    51301 catcatgggg ttaatcatgt ttggcggtaa tgcaaagagc gatgcaatgg aagcgattgc
    51361 ggctgctaaa atcggtgatt ttgagttagc ggataggaaa atcgctgatg cagaagaatc
    51421 acttatacaa gcgcatcatg cacaaacaga catgttgaca caagaagcac aaggaaatca
    51481 tatgcaagtg acattattga ctgttcacag tcaagatcac ttaatgacat ctattgcgtt
    51541 tactgattta gcaaaagaaa tcatcgaact ttatcgtcgc gtatacagcg aataaataca
    51601 acttcttttt tgaacggaag aagaaaaatt tttgaacgga ttttttattt tgttataagg
    51661 agaactctct ttatataaaa aacttatagg aggaagtaaa aaatgaacgg actatcaagt
    51721 tggatggaga aatacatcct gccggttgcc gcaaaaatcg gagcgcaaaa acatttagtt
    51781 gctttgcgtg atgcttttat cggcatactg cccgcaacaa tggcgggatc agtcgctgta
    51841 atgatcaatg caattattcg tgatttaccg caacagttta acagtaccta tgctgacagt
    51901 ttagcagcag acaaaggaat ctttgccgta ttgaatgtca tcatcggaat caatggtttt
    51961 gtctggaacg gtacactagc aatcgccgga ttgatctttg ccttttcttg ggggtataat
    52021 cttgcccgag cttatggagt aaatgatcta gctgggggga tcgttggttt agctaccttg
    52081 attcaaggta tttcctttgg tccagcatta tcagcagcat tagatgtgaa tgttccttca
    52141 aatgtcgcag atgcaatcaa tagttctgag attggtgcaa cgattgcaga tggcacactg
    52201 tcagttggat tatggggttg gctaaaacta gatcatttga atggaaacgc ttattttaca
    52261 gttatgatca tgggagctat ttcagtcatt attttttgta aattgatgct tgccaacatt
    52321 acgatcaaaa tgcctgattc agtaccacca gcagtatcta aagcatttgc agccatttta
    52381 ccagcgacga tcgctttata cgtcattgct attatcaatt atatcgtagg tcgtgtagct
    52441 gatgggcaac tgatcattga tttggtgcaa aaatatattg cagaaccatt cctaggatta
    52501 tctcaagggt tgggagcagt attgatcgtc acagtatttg ttcaagtatt ctggttcttt
    52561 ggtattcatg gatcaaatgt attggcacca gtgctagagg gaatctgggg acaagcacaa
    52621 ctaatcaata ttgatatttt ccaaaaaggt tataacggaa aaactggtac accagccgtg
    52681 ttagatgcaa tcgaagatgg aaaagcttat atgtgggtcc gcggatcgtt cgatgctttt
    52741 gcatggtttg gcggatcagg cggaacgatc gtcttactga tagctatctt gattttctct
    52801 aaacgtgcag attatctaac agtagctaaa ttatccattg ggcctggtat cttcaatatc
    52861 aacgaaccag tgatgtttgg tctgccaatc gtattgaatg caatcatgtt tatcccattc
    52921 ttgattgctc cagtagtagc aacagcaatt ggatggacag ctacttatct tggcctagtc
    52981 gctccggtat cgcagcaagt cacatgggta gtaccgccgt tcttattgtc attcttagca
    53041 acaggagcgg attggcgggc accgatcgta acattagtat gtatggtcgt gactttcttg
    53101 atttgggcac catttgtcat ctctgcaaac aaaatggacc ctgccgcagg cgaacaacaa
    53161 taagatgaac gtgaggagcg ggacgcttta agtttcgttc ctcataatga attttcgagg
    53221 aggaactgaa atgattacaa ttgccagtgc aatgcaacaa gatgaaatca aagaattgtt
    53281 agaaggatac aatgaagaag gaatgacttt tacatttaaa gaaaaacaag gaatcaagct
    53341 gttctttgaa acaagtgcag aagatccgga agttgcggct aaaaaagcaa aggaactaat
    53401 caaagcacag ccttggggaa cagtccttta ttttcaatca acagctgttt agaaaatggt
    53461 ttaaaaagat aggatggttg agatgataaa aaacggttta tttttatgta gtattggttc
    53521 tttgatcgtg ttgtatagtt tgaatccaca ttcgcaaagg tatgatttgt atagtatggt
    53581 cacaggtctt tttctaacag gattaggaat ctatttcttc atgaagggga aaaaaagaga
    53641 agaagcaaag gagaaaaata actaatggaa atcacgaaaa aattaaatat tccagcatcg
    53701 tttttttacg ataaagttat ggactctgtc cttttcgatg tacgtaaagc gaccggcaaa
    53761 tcagtaacta gaaaacagct gaaaaatttg gagtacgtca aacaattctc gcaaaataac
    53821 cgggctcgca taaaaatcga agaagtcatt gaaaaccagt cttataagtt tcgtacatcg
    53881 acaacgaaga atgaattcgt cgttcattat caaatcaaac cattggacga ttcgacctgt
    53941 gaggttcatt acacagaaaa aatggagtct tatggcatgc ttcaaaagtt gaatgatatg
    54001 cttttaggaa caatcttgat gtattttaaa cggagacgtt tcaaaaaaat gctagatatg
    54061 atcgaagcaa cgtattaaat caatgaaaca tggtactatt tagttattga aaaatgaagt
    54121 aagctagaag gaatttttca taggaagata gatctttcct gcgaatcctc actagctttt
    54181 ttgtaggaag gggcagcaaa atgacaaaca aagtaagaga gctaggtgta tcttcgattg
    54241 aggaaatgtt tgatttagcc acttatgcat ttaatggggc agatacacct gaaaggcgag
    54301 aacgttttcg tacacttgcg gagaattctt ggaattacgg attttttgat gaggaggatc
    54361 ggctaacaag tcaagtcatg gcgacccctt ttccagtgaa tttttacgga caagagtacc
    54421 taatggccgg cattggctat gttgcttctt atccagaagc aaggggacaa ggcgggatca
    54481 atcagatcat ggaaaagatc cttgaagatt gccgtgatcg taaagtaagc ttatcttatc
    54541 tggcgccatt ctcctatccc ttctatcggc gctatggcta tgaacaatca tttgataaaa
    54601 tcagttatca actaaacagt cgtgatgtgc cgtttatcaa aaaaaaatct ggaaaaataa
    54661 agcgtatgga ttttgaagat gcaaaagctg caatcagaag aatttatgaa cagatgccgg
    54721 aaaaccaacg agctggtctg aagcgcgaag actggtggta tacgtataaa ttcaagcaaa
    54781 aaggcaatta ccagtttgct ttgcattttg atgataatga ggaagcaacg ggatatatcg
    54841 tttatcagct tgcaacgtct tcctttatta ttgcggagtg gggatttttg gatcatgatg
    54901 ctttttgcag ccttgttcgc ttcgtaagtt ctcacaatgg tgcttttgaa acatttgaat
    54961 attcatgcgg ctacggcggt aatgatcaaa attatctatt agaaaatcca tttgcttctg
    55021 taatgatcac accttatatg atggcgagga tcgtagatat ttctttgttt ttggaaaatt
    55081 atccatttaa aaagagacaa gctgcatttg ccctacaaat agaagaagat cattatgcga
    55141 aatggaatga aggaatcgtg gaagtaacaa tcgaaaatgg aaaaaatcat ctctcaaaag
    55201 tagaacaaac aaaactccca atcgttcgag gaagtatcca acatatcacg cagctattat
    55261 tagggtatcg taaagtggaa gagttggtat tccaagaaag aatacaggtg acaaaagaat
    55321 atgaagaaac gttaagctca atcttgccac agcaacagcc aattcttaat gactattttt
    55381 gataaaaaac gggtgatgac aatatttttg tcaccaccct tttgtttttc atttggcatt
    55441 tgaaggaaaa tgttaaagta aatcctcttt tttcgtaaat ttgaattttt tgttttcttt
    55501 tgttttaggg ttttcttttt tgtggtcttg gattgcttct ttcgtaatct tttcccgatt
    55561 ttttttagat gaatctaagc gttctgcgta tactttttct tttggcttat cattcattgg
    55621 aaaggacctc cctacattat ttcattctac ctctagttta tcatctgtta aggactagtg
    55681 gaaacgtttt gcctaactta taagctgatt tttttagcag ataagcttgc aagtaaaaaa
    55741 caaacaagct acaattgatt tattgaaatt gttcctgtag ctcagtagga tagagcaatc
    55801 gcctcctaag cgataggtcg ctggttcaat tccagtcagg aacgtataaa taacccctgt
    55861 atcctttgcg gtacaggggt ttgttttgta tttgtgccaa aaatgtgcca aactagttat
    55921 catttttata taaactatcg aacacagtat tgattttttc tttatcctga tcttcaagct
    55981 ctcgaacaat atgaagataa gtagacattg tagtttctaa actgctatgt cctaaacgtt
    56041 tcgatacgct aagtatattt actccttgat aaagtaaaat agatgcatgt gtatgcctta
    56101 gtccatgcaa agtaaattgc ttttcaatcc ctaattcttt taattttttg cgcaaatatt
    56161 tgctgacggc gtttgatgaa actaatccat tttttaagtt gaaaaaaaca aaattatgag
    56221 ggtttttgat ttcaaaattc tcgaataatt ctttttgatt gattttaaac ttttttaaga
    56281 gatcaatcgt atgtttatca atggaaattt tcctatttga agtttcgttt tttgtttttc
    56341 cccattcatt taatttataa ttccatgttt tattaatagt gatgatttga tcttcgaaat
    56401 cgatatcttc ccatgttaat cctagaagtt cagcaaatcg cattccagtg gcaccagcaa
    56461 ctaacacgag cataggagaa gagtactgcg cagaaaggtt ttcttctacg agtttcatta
    56521 aagatttaaa ttgatcataa tctaaatatt tatcttcttt tggcttcaat gaatcttttc
    56581 ctttgattac tgcttttcta gttggatcaa acggaattaa tccttcttct acggcatctt
    56641 tcaacgacgc tctaatatgg ttattaaact taataacggt agattttaca tggtctttag
    56701 catacttatt taaaaagcgt tgatatccca ctctatctaa atcagaaatc aataccgctg
    56761 gcatatattt ctttatgttc attaacgtat cttcgtattt tctataagtg ataggagata
    56821 ctgttccttc tttataaagt tgcatccaat cctcaaagta atctgataat aatagatttt
    56881 tgcgatcccc tttaaggcct ttgttcaagt tatattctaa ttcgttggcg gcatcttttg
    56941 cttctccttt tgtcttaaat cctgattttc ttatcttcgt gtattttccg tcatcttttt
    57001 tgtatgaaat ttcgtattgc caactatttc cacgtttgac taatcttgcc ataattgaat
    57061 cagctctctt tctctgatac aataggaact ataaagaagc ccattgtttg ggttttatta
    57121 ttttttgcac atcctttttg cttgccggcg caaggatgtg ctatttgtcg ttttaatggt
    57181 ataattggat gtgtattaga tcatccaatc agaggtgttt attatgatta aagtgatttt
    57241 taaaagaata actgaacttc cagagtttag attatttgtt gattattggt atgtctggtt
    57301 ttttattgtt gcattgctga taggtctaga tgtcatatta gaaagaaaac ttaagtaaga
    57361 gttgagttaa taaattgaat tcctaaatga gatattttgt agcccatatt ttgtttgccg
    57421 acatcaccta atactatgga gctaatcgtt ttttctaaca gaccaaaatc agataatcta
    57481 tttaagctac catctattag ctcttgtgaa tagccagaca tgctgatatt tccagtgaaa
    57541 ttttcgtttc cacgactcat taagcatgct aacaattgaa tctcaatcga tgttaattga
    57601 ttcagtacaa gaagataata ctcctcgtta tcccatgaag cgttgttaat tcgaagtaaa
    57661 caattcttat aaagattttt atacatatct attttatttt gtgcctttga tttttctacc
    57721 tcgtcattta tcccttcgaa tattccaatg agttggtcct tgttctctaa gttgaaaaca
    57781 tcttctggaa tttgatcgcg aatgttttct aatgattcgt ttaaattttt gtagaatttc
    57841 tcgatgcgtt tgaaacgctt ctcgttttta gacccaaaat aaagtgactg cacaacgcca
    57901 ccaatataag gaattgctcc aataccgcct tcaactatta attcaagata ttcttttttg
    57961 gttagttttt cattgctatt atccatagtt acctcctatt ttgtcatttc ctttacaagc
    58021 attgtgactc ctgatggcac tcttttgtat aggttttatt attgtgcaca atctaactct
    58081 tagtggggcg tggttcattt attttttact tactttacta ttaatcatat cccattgagc
    58141 ataggatttt tctatgttcg atcctcttga actaatttct cctgtaaaag ttactttatc
    58201 gccctttgta aaggtatcag cattgtttaa gtccttcgca aaaattacat atgaaacttt
    58261 aggtgttgca gaaatatcat tccaactttt atcatcgtac tctttgtctg ctataatggc
    58321 tattctagta gtcattgatt cgataacagt tccttcaaaa gtatatgttt taccactaat
    58381 atatttagta aaagctgtat tttgctcagt agctggagta atagaataat aactatctaa
    58441 gaaagcaccc cagtcatgat tatttgtctc taaaaattct tcaaattgag ttaggctttt
    58501 attgctgctg ttagatgtag tagtttgagt atcagatgat gagctttcct gtttgttatt
    58561 gtcatttgcc tcgtttgatg aggaaagcga gaaacctacg gtagtaaaaa taatcccgat
    58621 aataaggaga atcataggtg ttttcttatt tgtttttttg ataaatctta caattaacat
    58681 gattaaacct ataataaata aaacaatacc agtaaaacca aatataccgt ccattaatag
    58741 atcctctttc tcttttgata ttgaatatta taaaccaagc aattcttttt tcttaaaatc
    58801 gaattcttct tgattaataa tcccttcatc taacaactct ttatactttt taatttcatc
    58861 tgcacttgaa atttgtgttt ctttggaatt attatctaat atagattgtt gcttctctat
    58921 atattttttt aaattttcca tttcattcca atattttttt gtaaacataa cggtgttttc
    58981 atctttcgtg gccgctaata tacctccgcg actttcgttt ccgcctagca aggtaaattg
    59041 tatataacca ttactcatac ctggtttttt taattgtacg gctgatatat ttttaaaggg
    59101 gatagttttt tctc
//
LOCUS       DAFLWZ010000009        58774 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000009 DAFLWZ010000000
VERSION     DAFLWZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.009"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..237
                     /locus_tag="L1V38_000586"
     CDS             <1..237
                     /locus_tag="L1V38_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1315159.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(661..831)
                     /locus_tag="L1V38_000587"
     CDS             complement(661..831)
                     /locus_tag="L1V38_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1315160.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1025..1204)
                     /locus_tag="L1V38_000588"
     CDS             complement(1025..1204)
                     /locus_tag="L1V38_000588"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315161.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            1591..2703
                     /locus_tag="L1V38_000589"
     CDS             1591..2703
                     /locus_tag="L1V38_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1315162.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2781..3074)
                     /locus_tag="L1V38_000590"
     CDS             complement(2781..3074)
                     /locus_tag="L1V38_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBN1315163.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3242..3556
                     /locus_tag="L1V38_000591"
     CDS             3242..3556
                     /locus_tag="L1V38_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBN1315164.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3577..5556
                     /locus_tag="L1V38_000592"
     CDS             3577..5556
                     /locus_tag="L1V38_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1315165.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5569..5895
                     /locus_tag="L1V38_000593"
     CDS             5569..5895
                     /locus_tag="L1V38_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBN1315166.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5911..6429
                     /locus_tag="L1V38_000594"
     CDS             5911..6429
                     /locus_tag="L1V38_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315167.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6429..7781
                     /gene="celB"
                     /locus_tag="L1V38_000595"
     CDS             6429..7781
                     /gene="celB"
                     /locus_tag="L1V38_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1315168.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7865..9370)
                     /locus_tag="L1V38_000596"
     CDS             complement(7865..9370)
                     /locus_tag="L1V38_000596"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBN1315169.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9462..10052)
                     /locus_tag="L1V38_000597"
     CDS             complement(9462..10052)
                     /locus_tag="L1V38_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1315170.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10231..11877
                     /locus_tag="L1V38_000598"
     CDS             10231..11877
                     /locus_tag="L1V38_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1315171.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11926..12645
                     /locus_tag="L1V38_000599"
     CDS             11926..12645
                     /locus_tag="L1V38_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1315172.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13124..14071
                     /locus_tag="L1V38_000600"
     CDS             13124..14071
                     /locus_tag="L1V38_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315173.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14083..15003
                     /locus_tag="L1V38_000601"
     CDS             14083..15003
                     /locus_tag="L1V38_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1315174.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15044..16501
                     /locus_tag="L1V38_000602"
     CDS             15044..16501
                     /locus_tag="L1V38_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1315175.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16846..17460
                     /locus_tag="L1V38_000603"
     CDS             16846..17460
                     /locus_tag="L1V38_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1315176.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17453..19177
                     /locus_tag="L1V38_000604"
     CDS             17453..19177
                     /locus_tag="L1V38_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1315177.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19174..20625
                     /locus_tag="L1V38_000605"
     CDS             19174..20625
                     /locus_tag="L1V38_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315178.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21098..23251)
                     /locus_tag="L1V38_000606"
     CDS             complement(21098..23251)
                     /locus_tag="L1V38_000606"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBN1315179.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23253..24299)
                     /locus_tag="L1V38_000607"
     CDS             complement(23253..24299)
                     /locus_tag="L1V38_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315180.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24449..25738
                     /locus_tag="L1V38_000608"
     CDS             24449..25738
                     /locus_tag="L1V38_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBN1315181.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25751..28453
                     /locus_tag="L1V38_000609"
     CDS             25751..28453
                     /locus_tag="L1V38_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1315182.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28438..29295
                     /locus_tag="L1V38_000610"
     CDS             28438..29295
                     /locus_tag="L1V38_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1315183.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29366..30265)
                     /locus_tag="L1V38_000611"
     CDS             complement(29366..30265)
                     /locus_tag="L1V38_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1315184.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            30434..32605
                     /locus_tag="L1V38_000612"
     CDS             30434..32605
                     /locus_tag="L1V38_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1315185.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32673..33014
                     /locus_tag="L1V38_000613"
     CDS             32673..33014
                     /locus_tag="L1V38_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1315186.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33290..35044)
                     /locus_tag="L1V38_000614"
     CDS             complement(33290..35044)
                     /locus_tag="L1V38_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315187.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35055..35891)
                     /locus_tag="L1V38_000615"
     CDS             complement(35055..35891)
                     /locus_tag="L1V38_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1315188.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35893..36576)
                     /locus_tag="L1V38_000616"
     CDS             complement(35893..36576)
                     /locus_tag="L1V38_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBN1315189.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(36735..38129)
                     /gene="uxaC"
                     /locus_tag="L1V38_000617"
     CDS             complement(36735..38129)
                     /gene="uxaC"
                     /locus_tag="L1V38_000617"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1315190.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(38168..39667)
                     /locus_tag="L1V38_000618"
     CDS             complement(38168..39667)
                     /locus_tag="L1V38_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBN1315191.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(39660..41081)
                     /locus_tag="L1V38_000619"
     CDS             complement(39660..41081)
                     /locus_tag="L1V38_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBN1315192.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(41141..42133)
                     /locus_tag="L1V38_000620"
     CDS             complement(41141..42133)
                     /locus_tag="L1V38_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315193.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            42365..44563
                     /locus_tag="L1V38_000621"
     CDS             42365..44563
                     /locus_tag="L1V38_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315194.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(45021..45893)
                     /locus_tag="L1V38_000622"
     CDS             complement(45021..45893)
                     /locus_tag="L1V38_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1315195.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            46193..47167
                     /locus_tag="L1V38_000623"
     CDS             46193..47167
                     /locus_tag="L1V38_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315196.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            47189..47881
                     /locus_tag="L1V38_000624"
     CDS             47189..47881
                     /locus_tag="L1V38_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1315197.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            47847..49355
                     /locus_tag="L1V38_000625"
     CDS             47847..49355
                     /locus_tag="L1V38_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1315198.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            49429..50532
                     /locus_tag="L1V38_000626"
     CDS             49429..50532
                     /locus_tag="L1V38_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1315199.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            50535..51872
                     /locus_tag="L1V38_000627"
     CDS             50535..51872
                     /locus_tag="L1V38_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1315200.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            51859..52737
                     /locus_tag="L1V38_000628"
     CDS             51859..52737
                     /locus_tag="L1V38_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBN1315201.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            52734..53657
                     /locus_tag="L1V38_000629"
     CDS             52734..53657
                     /locus_tag="L1V38_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBN1315202.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            53654..54064
                     /locus_tag="L1V38_000630"
     CDS             53654..54064
                     /locus_tag="L1V38_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBN1315203.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            54068..55636
                     /locus_tag="L1V38_000631"
     CDS             54068..55636
                     /locus_tag="L1V38_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1315204.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            55876..57294
                     /locus_tag="L1V38_000632"
     CDS             55876..57294
                     /locus_tag="L1V38_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315205.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            57306..58616
                     /locus_tag="L1V38_000633"
     CDS             57306..58616
                     /locus_tag="L1V38_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1315206.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        18891 a        10271 c        11969 g        17643 t
ORIGIN      
        1 gatgcgacac cagtaacttt caagatcgaa aaagaacaag aagtggcgat ctttttaaca
       61 aaagagaata gaaaagttgc tgatagctca gatataagag gaaacaatcc aacaagcagt
      121 ggaaataagc atcttccaaa aactggagaa accatcatta gccagtttat attgtcaata
      181 ttgggtgtgc tacttgtttt catcagtata aaatttagaa agaaacgaaa tatatgagct
      241 aaaataaaaa attgaataag catagttttt aaaatcaact agtacccatc aattgaatgg
      301 aaactaccga ttttagaagg ggtatacaaa caaatattag tatcggagta gagaaggttg
      361 aacccaacca gtaaataagt aaagacaatt ttgtgctgcg ttgagaagtg aaaaataaac
      421 ctttgtagta atactagtta ataaaaaata tacaaaaaca ctgcgaaaat cattcttgag
      481 tttcgcagtg ttttttgcct aatgactcaa gtttattggg taatactttg attttctttc
      541 tacaaataat cagcgatcag ttgtaatttt ttctctagtt ttaatggctc tttgtcaata
      601 aggagaaaaa caagtcgggt cttttgtctc ggaaagcttc aaccaactcg tgaataaagg
      661 ttacgcctcc ttgaaaggcg tggaaaaacc aagtaatcga tcaatcacca atttcgcatt
      721 tggtagaaca tgtttggtga gctgaaagta ggtggcgttc atgtctgtaa ctaagaattc
      781 tatttcttta ggattagtgc agctaaggaa atagtttgtt aatcgaggaa ttttttgtgt
      841 aggtaaattt tctcgattaa tttttctgtc tcgccatccg cggaaataaa actcagttta
      901 tcctcaacgg aaacgtgaga acgaaattca caaccctcaa cactcaagac agaattcttt
      961 tggaagactt tggtaaatag cttctcaact ctttcaatgt gcgaataacg gttgtcaaag
     1021 atacctaaca acttttcgaa ataaaaaata acgacacttt ttcagtcagt aaagaagtga
     1081 ttttatgtct gacatgattt gaaatcgagt gccttggacg gataaaataa ctttgagcgt
     1141 tccaatggct tcgacagttt ttacaggtat agcgctgctt ttttaggcgt ataaccattg
     1201 gcatatgatt atattattca aagtggacaa tggtttcctt cttcttgttt ttcaccacca
     1261 ttaatttcct atttccatct accacagcag aaccacaatt tctacagaca catggagcag
     1321 ggaagagaac tgcagcaacg atcaatgttt ttttcttctg taaggtttcg taagagacct
     1381 ctgtaatcat caaatttttg tctattgatc tcagaatttt tttgatagaa ccattcataa
     1441 agcatatcgt tctctcagtt gtttattttg tggtgattta atcatacaag aaaacgatat
     1501 gtttttttat aaaaacatga ataggaaaaa tagttgacaa gaaaatgaca acgccatatg
     1561 atgttccata gtatttacaa cctgtcatag atgactgtaa aaaataaaag taaaaagaaa
     1621 ggacgacaac aggtggattt ttatcagtct ctacaactag atccgtttat tttaaaacaa
     1681 aaaatacgag aagcagcttc taaaaaagaa aagtgcatgt atatttgttc attgttttta
     1741 cgatcattat tcatcgtatt gtttgccatt tgttttatca ttataattac aacattattt
     1801 gaatcgaagc ataaaccata cgctgtggtt ttattctgta tgttgatgag tattcgtttt
     1861 gttgactttg gttataagat ttcccattcg atcataggtt tagcaatcgt catgttctca
     1921 ctattagtag caccgtatgt ccagctgatc aaatggtcag ttatgggcat gttgattcat
     1981 tttattttac taagcagcat attaatggca accgctagtg atcccaaaat ggggaatgct
     2041 tctttgtacg gcttttcata tctctttatt gtttattcgt tacctaaaga ttcgttgaac
     2101 aagaatttct ttacacaaac aagtagctta ttatttttgt ttttttgttg gttttcagtt
     2161 ctcctttaca gaaaacatcg agaaaagaac aaagacaaaa gcttgtttaa agagattttt
     2221 ttgaaaggca tgtattcgca ggaaaaaatt tggatgctca tctatgcatt tggcattagt
     2281 cttttgatcg ttgcaggaga gtatgtccct tttcagcgat tgatgtgggc agggtttgca
     2341 ttttcttcta ttgtatctag ctatggattg atgtcgattg gtttcaaaga acgagcagta
     2401 gaccgaatca ttggctcatt gattggatgt gttttattta ttggtatcag ccaatttatt
     2461 ccttttaact gggtcggtat attaggtggt ctagctttag gtgtttgttc tacctataga
     2521 tataaaacag tttttaattc ttttggtgct ttggcaatca ctgccagttt attcggggtt
     2581 ccaggagcag taacgatccg catttttgag aatatccttg gggtatgttt aggaatcatg
     2641 tatattgggg tgactgaaat acttatccga aaaataagag aaaaacacgg tttgaatcat
     2701 tagatgagat cgaataaaaa ataaggaaaa agtgaagata cacatggatg ataaattgct
     2761 atcattccat gtgtatcttt ttacggtaaa tcagtgaaac gttcgacttt catttttaat
     2821 ttatactttt tacggagttc gtttatttga gccatcattt cggatttgtg atgcttttcg
     2881 attgcttctt catctttcca acggtcgatc agtaaaagag attctggatc ttctagtgga
     2941 aagtaatagt catatttctc gtttccttct tctgcacgaa tcgctttgac aatgtttctt
     3001 tcgaccattt cttctgcaaa ttttctggct tgtccatttg tacttgtata caaaatattc
     3061 actgtgatac tcactaaatc ccctcctgaa aaaattctat cactagtata tcacggtgcc
     3121 agaaattatt attcaagata tgatacacat tttttccgca atgctacgga aatatatatt
     3181 ttgaatagaa aacgcttaca agatatgctt ggtttataaa aataaaagga gtgattgatt
     3241 tatgaaaaaa gcattgatta tttgtgcggc aggaatgtca tcctcgatga tggcctcaaa
     3301 gacaacggat ttctttaagc aaaaaagaga agaggtactc gtagatgcag tttcagctac
     3361 agaaggcgat aatatgatta agaatagtga ttttgattta tttctgatca gcccgcaaac
     3421 gacgatgttt ttggataaat tcaaaaaatt aggagaatct gttggaaagc ctgttgttag
     3481 tatccctttc caagcgtatg tcccaatccc tacaggcatc cagaagttag cagaggtgat
     3541 cgaagagaac atatgatgga ataggagtgg atgataatga aacagaagga aaaattgctg
     3601 ttgagatatt tgattgatca caagaaggag tatgtcacca gtcaacgttt agcttctgaa
     3661 ttgttattat ctgatcggac aatccgtaat tacttgcagc ggatcaaaga gttagtagaa
     3721 aaaaacggag gtaagatcat tgctaaacca ggttatggct accaactgca tattttacaa
     3781 agactgacat ttgacttgtt tttgagtcgg caagaaatag tacctggata tgctagagaa
     3841 ccgcaaggat tttatgagtc cgaagatcga caaaagtata tattgaacca attgcttttg
     3901 gaagatgcca ttctttttat ggatgatttg gcagaagagc tttatatcag tcgttccagt
     3961 ttgacaaagg acatgcaaga aatcaaggag cgattgattc catattcact aaaaatcgtt
     4021 tctaagcatg gtcaagggac atggatcgaa ggggaagaaa gaaatcgacg gcattttatc
     4081 atggatactt tttttggaaa ccattatgga aattcattga aagaatattt agggcaaagc
     4141 cgttttttcc cagacatcag ttttgaagag ctagtcatta tcattctcga tgaaacaaga
     4201 gaagctaagt taaaagtttc ggattttatc atacagaatc tgactttaca cttggctttg
     4261 gggatcaaac ggctccgaga agggtttgaa atcaaggaat taggcatcga acaagaagtt
     4321 tctaagcgag tagagtatca agtggcgcag cggatcgttc aacgtattga ggtaatcgca
     4381 ggtgtatcgt ttcccgaaga agaaattgct tatttgacat tacatctcat ggctaagtcg
     4441 aatcacaaag aaaatcaaaa tgatcaggaa ctatcaaagg aattagcgaa agttctgaaa
     4501 agattgtctc aggaatttca tttttcatta gtagaggatc tccagctttt caatggacta
     4561 ctcgatcatt tgtcaccgat gatgattcga ttgagccgag gtattcgcat tgagaaccca
     4621 ttgactgagg agataaagaa agaaaatccc aaagtctttg acgcagtaaa aaggcatttc
     4681 agcaacatgc cggctttgaa aaactatacc atcaatgaag atgaatgggc ctatttggct
     4741 ttgcatctca tggcggcatt ggaaaaagaa agagctgcgc ataaactaca tgcattgatt
     4801 atctgtgcaa cgggttacgg cagtgcccaa ctattaaaga atcgcgtagt cagtgaattc
     4861 ggtaaaaata ttacagtggt aagtgtaaaa ggctattatg agatcaatga aacaacttta
     4921 aaaggaatcg acctgattat ttcttctatt gatctttcga caatgttttt caaaattcca
     4981 gttttacatg tcagtatttt tttgaatgaa gatgatgttc gtaaaatacg aaaggtagtt
     5041 ggagaatcta taccctatca ttcctcagat agaccgatac cagcattttc tctacagcaa
     5101 aaaaagcaga tttacaccga acagttgtct gaaaaatttt tcaagactta tacgtacgaa
     5161 ccgaaaaagg aagaaattct tcatgatttg ctgcaaaagc tgagcataaa tgaagaagaa
     5221 ggatatataa gagaaatgcg aaagcagatc cagcaacgtg aaaatatggg acaaatcata
     5281 ttcagtgata cagtggcagt cccacatccc gctgttccag ttggaatcga aacaaaggta
     5341 gccgttgcat tgattccttc tgggatgcag tgggatcaat atcaagaaat tcattttgtt
     5401 tttttagttt cgccttctta tgtcgaaaat gaaggaatta cggtcgtgac taaagcaatc
     5461 gttaggttag ttgaccagct aaaagtacag caggaaatct tagctgaacc tatttttgag
     5521 aatttcagca gtaaatttat caaactgatc gaataaggag gaaaacagat ggctgaaaaa
     5581 ataaacagtg aaacactaca agtgacttct tttgatatca ttttccatag cggaaatgca
     5641 cggacactga tacatgaagc atttcgctcg atgcgtaaag agatgtttga agaagtagaa
     5701 gagaagttgc gacaagcaaa tgaagagatt cttcatgcgc atcagtcaca aactcaactt
     5761 ctgaaagaat atgccagcgg gacaaaaata gaaatggaaa ttatcatggt ccatgcacaa
     5821 gatcatctga tgacgacgat gacattattg gaagttgcac aggaaatgaa ttatttgtat
     5881 caaaaaaata aatagaaagg aaggatcatt gtgcaggata cagtaaaaag gaaaatcgaa
     5941 ttagaaaaaa agcaacttag tttgaaaaac atgtatttca atcgttatct aatcgtacgt
     6001 tacctgactg cctttttctt tttcatgaac atgcaatgga tgattctgct tctatcagct
     6061 aaaagtttag gaagtagttt accgatgatt ctgattttag ctattttgcc tgcagtagga
     6121 gaacaagtaa agctttatcg aaaacaccaa acgaacgttc catggacaaa gtggtatttt
     6181 ttgttccaga gtgtctttaa tttattagtg attccagtgt tgtttacctc aggatttaca
     6241 ttcttgtatc cttttatggc aaataacaat ggaggacagt tatttgtttt cattcttgtt
     6301 gtaagcggta tttttgccag tgcatttata cagtatcgtt taaagaaaat ttcactcaac
     6361 caagaccaac agtatatccg tattaaacaa tatgaaaaag cgttatattt aggaaaggag
     6421 aataactaat gtttgatttt ttgcagaaat acctgatggg acctatgggg aaaattgcgc
     6481 aacttaaaat cgttcgggct gtcatggcag cggggatggc ttctattcct ttcacgattg
     6541 taggctcgat gtttttggtt ttaaatattt tgccattacc gttcccattt ttagaaggat
     6601 tttttaatgc aacttttttc aaagttagtg acttgtacat gatcgtcaat acaatgacga
     6661 tggggatttt atctatttac tttgccattg tgtttgctta tgaattaacg tcaattgaac
     6721 gagatgaaca aaaattaaat gttaatccgc tcacgggggc attactatct gtttttgcat
     6781 tctttatgtg tatccctgaa ttgatcatga ctgatggtaa aatcagcttg attgcttcta
     6841 tcaatgagac agaaactgta gtaaatggta ttaggatggg ctcttttgtc gaacgtttag
     6901 gaacttcagg aatctttaca gctattatta tgtcgattat tgcggtcgaa ttgtattgta
     6961 tgtgtgtcaa gagaaattgg gtcataaaaa tgccagatgt tgttccgcca ggagtttctc
     7021 gttctttcac tgctctgatc ccaacatttg tcattgcgtt tgtggtgatg atcatcaatg
     7081 gattattagt tgcactagga acggatatct tcaaaatgat tgctatccca tttgggtttg
     7141 ttacgcagtt gacgaataca tggcttggtg tcatggtgat ttatttcttg atccatgcat
     7201 tgtggatcgt agggatccat ggagcgaata tcatcacttc tttcttgacc ccgatcgtat
     7261 tagctaatat ggcagctaac gcacaaggcg caaattatcc gttggcagga gaattcaaca
     7321 attcttatgt aaccgttggt ggatcaggtg cgactttagg attgatcatc tttattgcat
     7381 tcctcgcgaa atctgatcag ctgaaagtgt taggaaaagc ctcacttgta ccaggattat
     7441 tcaatatcaa tgaaccaatc attttcggga tgccaatcgt ctacaatccc tatttagcgg
     7501 ttccgttttt cttagctccg atggcttctg ctacactcgc ttattttgcc attcggctgg
     7561 aaatcgtcaa accgatgctt gcacagatgc cgtggccttc accagtcggg atcggagcat
     7621 ttgttggtag tggtggtgat tggaaagctg ctgtgttagc agtcatttgt gcaatcatcg
     7681 cattcattat ctggttccca tttatcaaat tctatgataa taaattatta aatgaagaaa
     7741 gagaaaaggc agcagaatta gctagtgaaa agttaaaatg atttctaaga aaaaaggaac
     7801 tgtgacaaaa aatcacagtc cctttttttc ttagaaatgg gaaaccacta gtatataaat
     7861 accattattc ttcaatcaac cgcttcacga ttgcataatc cccttcataa ggttcatcta
     7921 caccattgat tttttgatag ggatccacgc cttttcccgc aataacgact gaatcttgcg
     7981 gagcgctttc tgctaaagcg cgtcgaatcg cttcaggacg atccatttca taatgaacga
     8041 tcaaatctgg attagtaatt gcttcattga tttcttccgc gatttttttc ggatcttcaa
     8101 atgctgggtc atctgccgtc aaaaaggcga tgtcagctgt ttctgatagc acttttccaa
     8161 aatcatgtcg acgggagatt gctttgtttc ctgggctgcc taatacaaca attacacggc
     8221 catctggatg ttcatttttg gcaaattcca gcaatgtttt caagcttaga taattatgtg
     8281 catagtccac atagacatgc gctccattgg attggatcaa ttgatccatt cggcctggta
     8341 cacgagcttc ttttaatccg tcttgtgcat cttgactgga ggcacctgtt agtgctgcgg
     8401 caatgatcgc actggctgca ttttcttggt tgaatcctcc agccagcaaa atatcataag
     8461 cagtatcgca gatagctaag cgatcttcat gagaagataa agtaaaaccg tgagtacctt
     8521 tatctgaacg gatcacttga taattgcttt cttccgaacg accataagtg atcgttggaa
     8581 tctggaatag atcggctgtt tccctaagta aatcaaaata gtcactttca tgatttaaaa
     8641 caactgtttt tgaattcaag atcaattgtc gcttgcaata gaaatagtca tcaaatgtcg
     8701 gatgttcgat cggactgata tggtcaggcg agatattcaa gaagattccg acatctaaag
     8761 tcaagccgta tacgcgttgt gttttgtaag cttgtgaaga aacttccatc actagatgag
     8821 tcataccatt ttcaactgct tctgacatca tacgatataa atctaatgac tcaggcgttg
     8881 tcaaatggga tttgaaatat gttttgccat ctaacgttgt attcatagta gaaagcaatg
     8941 ctgttttttt atttgttgtg tgatccaaga ttgcttttgt aaagtacgca gcagttgttt
     9001 taccttttgt tccagtgaat ccgatcactt tcaatttatt ttgcggatag tcgtaaaaag
     9061 ccatagcaag aagcgccatt gctttacgga tatccgttac gatgattcct actgctgaat
     9121 tttcgtatgg ttgttctgat acataatatt gaataccctg ttcgattgct gaatccaaat
     9181 attcttcttt gaaattcatt cctttacaga aaaacaaagt agaagcatca gcttttcttg
     9241 aatcataact taactgaaga aattcagctt tttctggtac atcaagatgc cagcctcttg
     9301 ttgaaacaaa ttcttttaat agattttctt ttaatagtaa atgacggatg tcttctaaag
     9361 agaagctcat tgattgatcc ctcgctttat tcaatttctt ggtttattat agcacactct
     9421 ttttaatata tcgtttgttt ccgctatgac aaaatccagc tttattcaaa ttttcttgac
     9481 acaggggaca agcggatgag tattttcata aacaatgaac tgactgtaat agataggaga
     9541 acgaatagtg tctccaacaa tccaaaaaca taataattca aaaagacgat aagactattg
     9601 gtaagtaaaa gtccttgcgg cattggaagc cgaaaaaatt tgtggaaaat aatcggcggt
     9661 atcgttatac cgccatttga ggccccgact gtgtacaatg tgtaaacccc aagactgaac
     9721 aaaagacttc ctgaaatcag tgaaaagaaa tgtgaggaga tcatttccac ttttggaaca
     9781 atctctaaaa caacaggaaa aagcagactt cccgctacag tcttaaaaaa tactgatttt
     9841 cctaatagga cagcggctag aagcagcatc ataagattga tgctccaaac agtaactgag
     9901 cgttggatag aaaaggccgt ttcaactaaa tgtccgatgg cgcccactcc ggcggaagct
     9961 atatcgtgag ggagcaagaa ccaattcaat ccaactgtga taaagaaaag acctaaaaat
    10021 ataacgggta gtttttttat ttcttgtgtc attgatatct cctataaatg ttagccataa
    10081 aaggctgtat atttctttac tttaccaaaa aaacgaaacc gaattcaaaa aaacaattgt
    10141 tcttataaaa gttatataaa atcgattgcc agtttctgtt ttaccaatta aaatgatagt
    10201 aatgttttgt agaaagttgg aatctgaccg atggataatc aaagaaaacc agcattagat
    10261 caattaacac cgcaagaaaa aatggcacga ggctctgctt ggatgaccgc cagtaatatc
    10321 atttcaagat tgctaggcgc tgtctatatc attccctggt atgcttggat gggcgaaaat
    10381 gctaaggctg ccaatggatt attcaatatg ggatacaata tatatgcatt gtttctactg
    10441 atctctacag caggaatacc tgctgcgatt gcaaaacaaa ctgcacgcta taattcattg
    10501 aatgaatatg gcacttcacg acgattattt atccgtgcat tacagatgat gggcgggcta
    10561 ggcctgttgt ttgctttgtt catgtacatc gcctctcctt ggctagctca tgcttctggt
    10621 ggcggagaag aactgattcc aacgatgcgt tctttgagta tcgctgtatt ggtttttcct
    10681 tgtatgagtg tgatacgagg gtattttcaa ggcaatcaag aaatgatgcc ttatgcgctg
    10741 tcgcagattg tagaacaggt ggcacgtatt ttttatatgc tattggctac attcatcatc
    10801 atgaaagtca tggatggtga ctatgtgacg gcggtcacgc aatcaacttt cgcggcattt
    10861 atcggtatgc tagcaagtat tcttgtcctt ttgtattttt tgaagaaaca tcaagcgtat
    10921 acatcggcgt ttattcacta cagcgaaaac aaaataaata ttgcaacgaa ggaattgttg
    10981 ttagataccg ttaaagaagc gattccgttt attattgtgg gttcaggggt aacgatcttc
    11041 aaattagtcg atcagttcac ttttatgaag atcatgtctg catccaccga gtattccaat
    11101 gcacagttac tggatctttt ttcgattttt agtgccaatc cagataagtt gacgatggta
    11161 gttattgcat tggcaacatc gatcgcgtct actgggttac cgttgattac agaagctgtt
    11221 acgttgaaag atcgagtagg tctggcaaaa ttgacaagcg gaaatttaca gttgttttca
    11281 ttttttatgt ttccggcgac atttggtgtt atgttacttg cctatccgct aaatacatta
    11341 ttttatacac cggattctct aggaagtaat gtactgatcc aagcaagttt tgtaggactc
    11401 ttcctaggac tatatatgct agtttccaac atgctgcaag gaatgtttga aaacaaggcg
    11461 gcaattaatt atttggttat tgggtttcta gtgaaactcc ttcttcaata cccagccatt
    11521 cgtttatttg aagtatacgg ccctttattg gcgacaatga tcggatttgc tgtgtcttgt
    11581 accttgatct taaagagaat ccatgaagta gcccgcttta aaccaagttt tgtctggcgc
    11641 aggacattgc tgatctttat tcttaccttg attatgcttt tggcttcgtg gatcacaaag
    11701 atgatttttg gtgctttttt aaacgaagat agcaaattcc agtctctatt gttgattctt
    11761 gtagtagcag gtataggggc tttagtgtat ggttatttag ctttgaaaat ccgcttggca
    11821 gaaagactac taggaccagg aatagcgcgt ttacgacata aattaaaaat aaaataagtg
    11881 aatcagaaga gctagattga tgctcttttg aaatggggga aacgcatgcg tttagataag
    11941 tttttagcag atatgggact tggcagccgc aaagaagtca aaggattgat caaaaaagga
    12001 acgatcgaag tcaatggaca agtggtgaaa agcgataaag cgcaagtaaa tgaattcgaa
    12061 gatgcggtta cttatttagg agaaatcatt acgtatcaaa aagattttta ctacattttg
    12121 cataaacctg caggagtcat ttctgctact caggataatc atgatcaaac cgtaatcgat
    12181 ttattggaag accaggatta tcgggaagat ctttttccag tcggccgatt agataaagac
    12241 acagagggcc tcttgatttt aacgaatgac ggggtgtttg cccatcagtt actatcacct
    12301 aaaaaacatg tggagaaaga atatctagct gaggttagcg gtataatgac agaagaagat
    12361 atccgtttat ttgcagaagg actgattatt gatggcgatg agcagacatt gccggcaaaa
    12421 ctccaaattg atcaagtaga tcaagagaca gaaacttcaa ttatccgtct gattttgcat
    12481 gaaggaaagt ttcaccaagt taagcgaatg gtcaaagcag taggaaaaga agtcttatat
    12541 ttaaaaagaa tccgtatggg aaaattttgg ctgcctaaag atttgaataa agggcaatat
    12601 cgacccatga ccaaagaaga gctagaacaa gtgagagaaa aataattgaa tggatagcta
    12661 aaagaataag cagagtagtt gtagcgccat ctgaaaagca gacttgtccg tctgactttc
    12721 ggatggcttt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    12781 tgttcggaat aagggactgt gacaagactt ttgttacagt ccccattgtt ccttgtgact
    12841 cagagttaga tagtaaggac acgatctccc taatactcag gccaaaacgc tgaattcaca
    12901 acctctgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
    12961 tatgaggaac tattttcccg tttttttctc taatactcag gccaaaacgc tgatttcaca
    13021 acctctccta tactttgttt cattttccct atactttgtt tatttattct cattattgaa
    13081 agcgctataa ttacgttgcg aatgaatcga aaggggtttt tagatgaaaa aacgaaaggg
    13141 gttcaatcat ttttttatga atctatggcg ttataaagca cttgtcctga tggctgtacc
    13201 gggtatgctt tggatgattt ttttctttta catacctgta atggcgaatg tcgtagcatt
    13261 caaaaatttt catatttcag cagatgggtt cttggctagc ttgagggaaa gtccttgggt
    13321 gggttgggaa aatttcaaat ttttattttc ttcggatcaa gcatttctca tcactaaaaa
    13381 tacaatttta tataatgtag catttatcct tttgaatctg ctgatctcag tcgtatttgc
    13441 aatcattatg agcgagttga gaaataaacg actcgttaaa gtttatcaaa cgatgtcctt
    13501 actaccttat tttctatctt gggtcattat cagttacttt gtttacgctt ttttaagtcc
    13561 tgacaaagga atattcaatc agtggatcac tggacatgga ggagaagctg tcaattggta
    13621 taatgaaccg aaatattggc cgtttatctt ggtgttcatt ggtacatgga aagggattgg
    13681 ttataacagc attatttact ttgcatctgt tatgggaatc gatccgactt attatgaagc
    13741 tgctatggtt gatggagcta gcaaatggca gcagatcaaa catgtgacga taccacaact
    13801 tattccacta atgacgattt taacgatttt agccgtagga aacattttcc gagctgattt
    13861 tggcctgttt tataacattc ctaggaattc cggtgcatta tatgatgtga ctcaagtttt
    13921 ggatacgtat atctacaatg gcctgacatc cacaggagat tttggtatga cggctgctgc
    13981 aggactttac caatcagttg tcggctttgt cttgttgatg atcacaaata cgatcgcccg
    14041 acgttttgat agcgattctg cattattcta aggaggaaaa aaatgaaaaa aaagaaagtg
    14101 gagagagtcc aagtccgctc tttcaataag acggctaatt ttttctctaa tataatgatt
    14161 gcactctttg ctatttcctg tattttgcca tttatatttg ttatcgccat ctcttttacc
    14221 gatgagtcca tattgtcgac tcacgggtac agtttttggc cagaaaagtt cagtatattt
    14281 ggttatacgt acttgttcga ccagatgcag gataaaattt tccaagcgct tttcgtcact
    14341 gtacttgtta ctgttttagg tacactgatc aatagcacgg ctacttcttt atatgcttat
    14401 gcgatttcac ggtcaaactt tccattccgt cgttttttta ccgttttttg tttgattacg
    14461 atgttgttct caccagggat ggtggccaat tatcttgtta tgacaaatct tcttcagtta
    14521 aaagatacga tttgggcatt gatcttgcca atggctgtca gtcccttcaa tattattgtg
    14581 atgcgcacat tctttaaacg ttcggtctct gattcgatta ttgaatcggc acggatcgat
    14641 ggagctagcg aactgcgaat atttgttcag atcgttttac cgttagctgt tccaggtatt
    14701 gcgacaatca gtttatttgc cgcattgggt tactggaatg actggttcaa tgctttacta
    14761 tacatccaag atgataagct agttccacta cagtatcttt tgatgaaaat ccaaagtaat
    14821 attcaatatc tgacacaaaa ttcaggagca ggaagccaat tgacaggcgg attagcctca
    14881 gttccaggag aatctgccag aatggcgatc gtagtcatct cgacgttgcc tattgcgatc
    14941 agctatccat ttttccagaa gcattttgtc aaaggtctaa caatcggcgg agtaaaagaa
    15001 taaagaaaca aaaatataaa tcataaaatt aggaggaaga aaaatgaagt tatggaagaa
    15061 actagccttt acaggtgttt cagcgttgtt gttgggaaca ttagcagcat gcggaggttc
    15121 tggttctaaa gaccaggcag aagctagcaa ttcggacact ttgcagatgt atcaaatcgg
    15181 agataaacca gataatttcg atcaattgat ggaagtagca aacaaacgaa tcgaaaaaga
    15241 gatcggtgta aaagtcaata tcaattacat tggctggggc gattacgaaa agaaaatgaa
    15301 cgtcatcatt tcttccgggg aaaattatga tatcgccttt gcgaacaact atgtttccaa
    15361 tgcccaaaaa ggagcctttg ctgatttgac tgaattagcg cctaagtacg ctgaaaaagc
    15421 ttataatgat ttagatgaag catatattaa aggaaatctg gtcaatggaa aattatatgc
    15481 tttcccagtc aatggaaatg tctttgctca acaagtactt acttttaaca aagctttact
    15541 agataaatac gatctttcaa ttgatggaat ccaatcttac gctgatgcag aaaaagtctt
    15601 gaaggaattc catgaaaaag aaccaaacac ggcagctttt gccattggac aaggcttcaa
    15661 agtccaaggg aactttgatt atcctttagg gaatacgtta ccatttgcta ttgatctgga
    15721 tggagatgat tcgaaaatca tcaaccaata cgataatgaa acgtatatcg gactgttacg
    15781 tacaatgcat agctggtaca aacaaggact cattccaagt gacgctgcaa cgagcaataa
    15841 ggattatcca ctagaaggaa atacttggct aatgcgtgga gaaacacaag gaccgtatga
    15901 ttatggcgat acaattttga caaatgcagc aaaacaagaa cttgtctcaa aagcaattac
    15961 tgttccacta aaatctacag ctcaagcaca aatggcaaat tttgtcgtat caaatacttc
    16021 aaaaaataaa gaaaaatcag tagaacttct agggctgctt aacagtgatc cagaattatt
    16081 gaatgggctt gtttggggga tcgagggaga agcatgggaa aaagtcgatg gttcagatga
    16141 taaaatcaaa ttgctagatg gttatcagcc aaatacacat atgtctgctt ggaatacagg
    16201 aaacaacaag attctatata cacaagagtc tattacggat gacatgattg ccaaacgtga
    16261 tcaatcgatt gctgatgcag aaacttcacc gattttagga ttcagcttca acactgacag
    16321 tgtcaaaaca gaattaagta atatttctaa tgtcatgaat caatatttag atggattgaa
    16381 tacagggact gttgatccag atgaaacatt accgaaattg aaagacgctt tggacaaggc
    16441 tggctatgat aaggtattga aagaaatgca aaaacaatat gatgagttcc gacaagaata
    16501 ataatgaata aagacaaagg ggttgtgaca aaagacgtgt cacaacctct tgttccgaat
    16561 aaacggtgtt caaaagccag tttctcggta ttaagctaaa tatatgtaaa aatgtggaaa
    16621 gccatattca caaaattttt cttactactc gaaactaagc ggctatttca caaactcttg
    16681 gtaaacggtg ttcaatcagc taaccctcgg tattcgctca caaaacgaca aaatatgagg
    16741 aactattttt ccgtttgttt ctctaataat caggtcaagg tgctgattgc ccaacctttt
    16801 tttgtataat gagaaagtat aaacttaatg tttggaggag aagatatgtt agggaaggtt
    16861 ttggaagagt tatttatccg gatctgggtc attataaaac taaccttgta tttctggata
    16921 tatacatttg ccggcgggat catctttgga ttaggtgcgg catggaaaac agtcaatgaa
    16981 ctattttatt tgtacggatt cgagtataaa gaaatcacaa taaaaagagg ctggaatata
    17041 tataaaagaa attttttaag aggcaatctg ctatttagtt tatttttatc tggtactgct
    17101 ttattgagtt acaatttata tttatctgtt caaatcaaag ggctcatttt tttagctatt
    17161 gattttattt tactttttgc cttgctctgc ctatttgcta cttatcaata cagtatgatt
    17221 ttagatagtg aatatacgat ctctgttcct aatctgctaa agctaagttt tatttcggtt
    17281 ttttccagct tttcgtcttt tctaaaaata attattggta gcggtataat tttaggcgtg
    17341 acttggcaat tcaaaggatt gatcctgttt ggtgtcattg gtcttttgac ggtttggaat
    17401 ggtacgatga caacacattg gcgtgaagaa ttagataaac agttggaaag ttatgaataa
    17461 gtttcggatt ctattttcaa aaggaacctt actaaatcgt ctgttgcgga aatacgcggt
    17521 tatcatgatc ggtgtaacga tgactgctac cgttattttt agtatccata cttgggaaca
    17581 aaatcaaaaa caggcagaaa acatgacaag tgatgccgtt caaagcacaa gcagaatgct
    17641 gaatgataaa acaaccttga gtaggatcat caaaaaccag cttgtaggga attccgaaaa
    17701 gatcgaaaat gtgacgacct acttaacaaa acccatagat cagtatctga tgtatgtata
    17761 cgaacagcaa aacagtaccg atgaattagt ttctttccca aatcaaatca aagatctcta
    17821 cgcaaattat gaagaactaa gtgcgatata tatcgtgttg aatcaactac cggagtatta
    17881 tgaatcttct agagaaaaca aaggtgggga aataaaaaag gggacaccaa aattactaga
    17941 cgccttttat atcaagttgc ctatcacaca aggaggagct gagtcaggaa gtatttttat
    18001 tggttttcaa aagaaagaac tagatatgat tttagaaaat ctaacgtcat tcaatggact
    18061 ctctttatac atgatttctg gaacgacaaa tcgactatac acattccatg ataataaaat
    18121 agctaaagaa acgtttgaaa gacaagaaat gatcatcaca gagagtctga agaaaaattc
    18181 acaattgccg attgacgatc tggaaaaaaa caattttgtt caacaccaag aactgtctga
    18241 tgattatcgt atattagctg tactagataa aaaaagtgta aaaatcgaaa cgggaaaaaa
    18301 tcttgccccg ctgatcattg gtatcattat tttagacaat atactgctta tctttcttta
    18361 taaaacattc aaacgatatt cacagcaagt atctatcgtc atgcaggcca tggatcaaac
    18421 agcagcaggg aatttagaga cgcggatcga cataacaaac acggaatatg aactgaagga
    18481 actttcaatc ggtatcaacg aaatgttgga tagcatcaat cagtttgtag aagacatcta
    18541 caaattagaa atcaaacagc aagacgcaca tatgcgggcg cttcaagcac agatcaatcc
    18601 acacttttta tataatacat tagaatatat ccgaatgtat gcaatcagcg aaggaagtga
    18661 agaattagca gatgttgtgt atgcgttttc cgctttgctt cgaaacaata cgaatcaaga
    18721 gaaaacgatc actttaaaag aagaactgga cttttgcgaa aaatatgtct atttgtatca
    18781 aatgcgttat cctaatcgag tagcctatca ttttatgatc gatcctgatt tggaaaagat
    18841 cgaagtacct aaatttgtga tccagccatt agttgaaaat tattttaaac acggtattga
    18901 ttttactcga ttcgataatg cgctaagtgt caaagtcttg caggaaggca aacgggtaag
    18961 gatcatcatc aaagataatg gaaaagggat gactgaaaaa cggctaaaac agattgaaga
    19021 aaaactgtct catcctaaag tggaacttca cggttctatc ggtctgcaaa acgtgaatga
    19081 acgtttacgt gccagcttcg gcagcagtta ttatatgtcg cttgagaata atgagacagg
    19141 tggactgacc gtttctatta cattcaagga gggatgagcg tgtatcaagt gttattggta
    19201 gatgatgaat acatgatttt gaatgggtta aaaaagataa ttgattggca aagtttaggc
    19261 tttcaaatag tagcaacagc agagaatgcc aaagaaggac tagctgtact tgaacagcga
    19321 cagattgatt tagtagtaac ggatgtgaca atgccagaaa taaatggact ggaatttatt
    19381 gaagcggctc aaaaagaacg tcataatttt gaatttatga ttttatcagg ataccaagaa
    19441 ttcgattatt tgaaaggagg tatgcaatta ggcgccgtga attatttgat gaaacccgtg
    19501 aataagttcg aattggttga aagcctcaag aaaatcaaaa cacggttaga tcagcaaaat
    19561 gaacaaaaaa atcaacaaga aatctatcaa gaactgttat tcagtcaatg gttgaatgaa
    19621 gaattggatg aaataagtga agaagaaata ataggacaaa taagtgagaa gcagcatagg
    19681 atagtattga ttcaactggc aagaactcat gatactctta tcaatagatg gttgcaagaa
    19741 cggcaacaaa tcttttacta tcaacgaaat tacggagacc gtgtattgat cacgttgttg
    19801 ttggaggcag atgaagttga tggcttctgt tgttttgttc aagaaaactt tcctgatcag
    19861 gaatggctga tcagtatcgg ggaagagaca gattctttgg acaaaatccc tgaaacattc
    19921 caacaagcga aagacaatct acagttgcat caattttatg gagataaaga cgagcatgtt
    19981 ttttacgcag tacaagcaga aacaaaagat caaaccatcg atttttcaag tttcagacgc
    20041 gtgctgcaaa ataaacaatt ggaagtcgct caaaaaatga tcactgattt ttttgaacag
    20101 tttcagttag cagccatgat gccggaagat atacgatatt ccagtttttt actgtttatg
    20161 gagattcaac gggaattgat tgatctggaa gatgaggaat atttacaagg aatcgaaaaa
    20221 atccatcagg caaaaacggt gcaagaactt cagcagctac ttctgtcatt catcaaaaag
    20281 catcagagac agaaaaagta cagtgacaat gtggaaaaag taatcgtaat cctgcaccag
    20341 cattatcaag aaccacttac actcaaagaa gtgtcagaaa acctgcattt aaatgtcatg
    20401 tatctaggac agctgttcaa aaaagaaacg aaaaaaagtt tttcagctta tttgaaccat
    20461 ttacgtatgg aaaaagcgaa acaactgctt ttgcacagta atcaaaacat caatgagata
    20521 gcaagtgaga ttggctacaa caacaccacg tatttctcta aattattcaa gaaaatcgtc
    20581 ggcagatccc ctaaagagta ccgagaaaac agtggagaat cataaaaaaa aaagccaatg
    20641 taatgaaata acttataaaa aattgtctag aaatctaatt ttgggctgtt cttattactt
    20701 gaggcaaggc agctttttca tgacctctcg ataaacggag ttcaaaagcc agtttctcgg
    20761 tattaagcca aatttatgca aaaatgtgga aagccatttt cacaaaattt ttcttaatac
    20821 tcgaaactaa acagcttttt cacgacctct ccactaaatg gtgttcaatc agctgaccct
    20881 cggtattagc tcaaaaaatg gcaaaatatg aggaactatt ttgccatttg tctctctaat
    20941 actcaggtca gaacgctgat ttcacaacct ctcaataaac ggtgttcaaa agcttgcatc
    21001 tgcggtaata agaccaacca aacgaaaaat atgaggatct atttttgctt ggctgttctt
    21061 attacttgat gcaggacagc tttttcacaa cctcttgtta attatagttt gataaggaaa
    21121 aaggcaaatc ttttgcttga tatttcttag ggtgagggat gatccctaat tggtaagaga
    21181 tcgtgccgcc tttcagcaaa tcttgatggg taaaatataa tttcgtatat tctctgtcca
    21241 tccgtttgat tttatggata aattgttgct gcggccgatt aggcgttgct tcaatcgtca
    21301 attcctttcc atttgacaaa agcaaaacag ccttgtcaat taatggcata ccgataacat
    21361 attcaccggt tccaggcgtg acaggataaa atcccagact attgaagata taccaagcgg
    21421 ccatacttcc attgtcctca tctccagggt aacccattgg agaatcgtcg aaggtctgag
    21481 tcatcaactg tttaagcagt ggctgtgcca tttcaggttg tcctatataa ctgaacaagt
    21541 aaggatagtg aaaacttggc tggtttgaaa tagctaattg tccaaattct atcgcggcca
    21601 tctcactcat ttcgtggatc tcaaaaccat atcctcctgg gtcaaacgtt gggggctgat
    21661 tgcacagctc aatgagtttt tctttatatc tctcactgcc accatatttt ccgatcagtc
    21721 ctgaaaaatc gtgataaaca gcaaagctgc tttgccaagc acttccttct gcataatctt
    21781 gtccccaacg attagctgaa aatggttctc tgaacttgcc atctttatct tttgaacgca
    21841 taaatcctga ctcatagtca aagatatttt gatagttcaa tgattgctgc tgatatttct
    21901 tcgtcatttc ctcttcttct agtaccttgg caacttggct aatacaaaaa tcgctataag
    21961 catagtctaa tgtgtgattg actgattcgt ggtagtgatt aggaacatag ccatatgtca
    22021 agtaatcttc tgttccttgg cgtccataat ttggatgttt gctttgaacc gtagcacctt
    22081 tttccattgc cgttagaaat tcaggcatca agtctcgtcg gatatctttt acagcagcat
    22141 ctgcaatgac cgcatcgatc aatgtcccag gcataagtcc acgttcatca ggagacagcc
    22201 attttggcaa atagccactt tctctatagc tgttcaaaaa accttccagc atttcttcgt
    22261 atttttctac agcaatcaaa gaataaagag gataaaccgt tttatacgta tcccaaaacc
    22321 cattatttgt atagagaaca ccaggtttta tagatcgact agtcgtatca tagtggattt
    22381 tttgcccact aggatcaatt tcataaaatg tttgtggaaa taaaaacacc cgatataaat
    22441 tatgataaaa cgtccgcaat tgttgttgat catggtgtgt gagctgtata cgatcaaaat
    22501 aggactgcca ttgttcttga ctgtgagcaa ggtaagtctc tttgctttgg ttttgttcta
    22561 gttccaggtt ataagctgct tgttccgagc tgataaaaga tgtcccaaat cggatagttt
    22621 gtttttttgt ctgttcaaaa tacaacggga tcgagtcgct atttttgttg gaaacagcta
    22681 actcatcaat tgttaaagga tattcaaatc tcaatataaa ataaaaagaa aaatcaggat
    22741 cttctgaacc agcaaaatgt gtgatttttc cttccactgt gtaaggatct ataacaaaga
    22801 gctgatggcg tcccggaaag gataaaagta aaccgctgtc atttttgctg taatcaatag
    22861 ataagattcc gccatacatg ctaggtatca atgtagaaca gatgccataa cgtaattgac
    22921 agatcgacag atgagtcggg caaaatatac tttcttctgg gcggtaagaa ctttgagcat
    22981 ggaaaagggt gttctcctgt agttttccat tgatcggcgt aaacagcata tgactgaaat
    23041 cacccatcca aggacttggt tgatgggtaa gacggtagcc ttgaaaaacg cggtcatcag
    23101 gatgaaacca ccagctgccg ttttgatccg tagtttgcgg tgcaaaataa ttcatcccaa
    23161 aaggaacgcc agtataaggc tggcagttcc cattagagaa atttggctga ttcgctgttg
    23221 catgtctagt atctatttga ccgatattca ttttatttct cctttgttga ttgtcttttg
    23281 atgaatgaaa ctggaaattt actatcggat ggtcgatctt ttgtctctaa ccaagtgacc
    23341 aaagcatctc ccgcaagctt acctaactgt tcaaaatctt gtgcgatggt tgtcagtggc
    23401 gggtcaacaa gagctgctgc ttggatatca tcaaatccga taattgaaaa atcttcaggg
    23461 atatgataac catgctgtct caagagattc atggtctgga tagcgacaac atcgttttca
    23521 caaacaaaag cagttacttc atacttagtg atataagaaa gcaattcatc taatgtcgcg
    23581 cttttgtcat ccagtgaagt gtggaaagtc aaaccagctt tgtccaatgc ttcaaggtaa
    23641 ccaaggtaac gctgtcgaac ggattgtgga tgagtctgcg taccaaacaa ataagcgatt
    23701 tttgaatgtc cctgttcgat caaataagag gcagcaagcg caccgccttg gaaattatcg
    23761 gaaagaacgg taggaaaagg taactcatag atttttttat ctaatatgac gacagggaat
    23821 tctttcaatg aaagctcaaa aagtaagtca agatgttgtt ctgtatcaag agcataataa
    23881 atcaatccgt caaattcatt gattagctct tttgctgttt tattttgtag aaagtcaagc
    23941 gtcgtcatca tgacatcaat ctgtttatct tgcatcacag ggttcaatcc cttgctaaaa
    24001 tcaccaacag acaaatcagc gacatatgga agaagaaaca gaatccgtcg tgtttttgta
    24061 ggagaagcaa gaatctgttc cggagaagcg gatttaacga aactgccttt cccgcgaacg
    24121 cgataaataa gtcctaattg ctctaattca gtcaatgcac gtttggaagt gattctgctt
    24181 actttatagg tacgtgaaag ttctttttca gttggtagtt ggctgtctac aggtaattca
    24241 ccagttaaaa tagccgtttg caaatcatta aatattgtct ggtacaatgg ttgagtcata
    24301 taaacacctc ttaatgatat atcatattca aataatacca taatggatga aaaagtaaat
    24361 aaaaagatat tttttgaaag cgtagacata attggctgta tgaagtataa tctttaaaga
    24421 tatatcaaat agaaagaagg ttttattagt ggtttataaa gatataccaa aatcggtgca
    24481 gaaatttatg gaagatatca cacaaaaatg tggggatatc catgcggact gggcaaagaa
    24541 ttttacagca gcatttgcca atactctgtt gacaacagtc aaaaagcaaa atgacggaac
    24601 caccttttta ttgacgggag acattccagc gatgtggtta agagactcta ctgcacaagt
    24661 tcgtccttat ttagtgattg caaaagaaga tgaggaatta gctgacatga tcagcgggtt
    24721 agtcaaaaag caattttttt atatcaatat cgatccatat gcgaatgcct tcaacgaaga
    24781 agctaacggt gctggccacc aaacagatca tacaaaaatg aacgattgga tctgggaaag
    24841 aaaatatgaa attgattctt tatgctaccc aatacagttg gcctatcttc tttacaaaaa
    24901 tacaggaaaa actgatcaat tcaatcaatc ttttattgaa ggtatcaaaa aaatcttgga
    24961 cgtgttcaaa acagagcaag atcatgaaca ctctccttat acatttgtac gagacacgac
    25021 aagaaaagaa gatacgctga tcaatgacgg gcgaggtgca aaaacagctt ttacaggaat
    25081 gacatggtct ggtttccgtc ctagcgatga tgcttgccgt tatggatatc tggtaccatc
    25141 caatatgttt gcggtggtcg tgttaggtta tgtggaagaa atttttcaaa cgatactcga
    25201 tgataaagaa attgtacagc aaacacagaa attgaagaaa gagatccaag aggggattca
    25261 gaatcacgga cgaacggtta atcaaaaagg gcaaacgatt tatgcatatg aagtagatgg
    25321 aatgggaaac gccacagtca tggatgacag taatgtgccc aatctgatcg ccgcacctta
    25381 cttgggatat tgttctgaac aagaggaaga ttatctgcaa acaagaagaa cattgttgag
    25441 taaagaaaat ccatatttct atgaaggaaa gtacgcaaaa ggaattggat cctcccatac
    25501 gccagaaaaa tacgtttggc cgattgcatt agctatggaa ggaatgacaa cgtcagacaa
    25561 atctgaaaaa gagcggatat tgaatttact tgtagcaact gacgcaggaa cacaccttat
    25621 gcacgaagga ttcgatgtga acaatcctga aaattatacg agagaatggt tttcttgggc
    25681 aaatatgatg ttttgcgaat tagtcatgga ttactttgat attagagtag aaaagtagga
    25741 ggtatcgtaa atgaaaaaga aagtatatat catttctcat agccactggg atcgtgaatg
    25801 gtacatggct tacgaacagc atcacatgcg actgattgaa ttgatagacg atctactaga
    25861 gctatttgaa gttgatccgt ccttcaacag ttttcatttg gatgggcaaa cgattatttt
    25921 agatgactat cttcaagtaa ggccagaaaa aagacaggca atccaacaag caatcaatga
    25981 aggaaaattg agaattggac cattttatat cttgcaagat gattttctta tcagctcgga
    26041 atcgaacgtg agaaatatgc tgattggcat ggaagaaagc cgtaaatggg gaacccctgt
    26101 catgttaggc tattttcccg atacatttgg aaatatggga cagacgcctc aattaatgaa
    26161 acaagctggt atttcagcag cagcgtttgg ccgtggtgta aaaccaattg gctttgataa
    26221 tcaagttttg gaagcagaaa actattcttc ccaatactca gagatgtggt ggaaaggccc
    26281 tgatcaaaca gcaatctttg gtctgctatt tgccaattgg tatagcaacg ggaatgagat
    26341 tccagtagaa aaagaagcag ctcttgcctt ttggaagcaa aaattagcgg atgcagaaca
    26401 atatgcctct acgaaccact tattgatgat gaatggtgtt gatcatcaac cggtacaaaa
    26461 agatatatca aaagcaatcc atctcgcaaa tgaactgttt ccagattacg agtttattca
    26521 ttctaatttt actgactatc tggaagcagt tcaaaaagat gtgccagaag acttaggctc
    26581 agtagaagga gaattgacaa gtcaagaaac ggatggctgg tatactttag ccaatacagc
    26641 atctgctcgg gtttacttaa aacaatggaa taccaaggtc cagcgacagc tagaaaatat
    26701 tacagaacca cttgcgacga tggcttatga agttagtgga aactatcccc atgatcaatt
    26761 agattatgct tggaagacat taatgcaaaa tcatcctcac gacagtattt gcggttgttc
    26821 agtcgattct gtccatcggg aaatgatacc tcgttttgaa aaagcagatg aagttggaaa
    26881 gtatcttgca caagattcct tagaacagct gaccgcagca atcgatacga ccggattccc
    26941 aaaagacagc tttccatttg tcattgtaaa tactgcagga atggataaaa ctggtgaagc
    27001 agaaataacc atcgaattag aaagaaaaag attcgctgaa ggaatacctg aacaactata
    27061 tcaagagtta gaaaatttgc ctaaacgtaa gtatcatgta gaaacaaaaa gtggggccac
    27121 tataccagct attttatctg aagaaactgt ccaatttggt tatgatttgc cgaaagaccg
    27181 tttccgtgtg ccatatatgg caagaatgat caaagtgact ttaccattag aaaacatgcc
    27241 agcattttct tgggaaacat tcgcgcttgt agaaggggaa gcgaaagcag aagaaaagga
    27301 aacaatgatt catcagagtg gacgaatcat cgaaaacggc cctctacatt tgacgattga
    27361 aaaaaatggt accattacaa tggaagatcg caaaaacaaa cgaaagttga ataatctgca
    27421 tatttttgaa gatatcggcg atataggaaa tgagtatatc tttaaacaac ctttctgtga
    27481 tcagccaatc ctatccagta acaaagaaaa ctctgaagta aaagtattag tagatacacc
    27541 ggaaatagca aaaataagta ttctacagga aatggaaatc cctgtttctg cagacgagcg
    27601 tttagaaaaa gaacagcaga tggttgtgga atttcgttat cgaaaagcag aacgatccaa
    27661 agaaaaacga atccttcaaa taaaaacaat catgacaatc agaaaagata gtaaaaaaat
    27721 cgactttgaa acgactctcg acaatcagat gaaagatcat cgcttacgtg tcttgtttcc
    27781 tacaaagtta catgtggaac atcacgaagc agatagtatt tttgaagtgg tgaagcgccc
    27841 aaaccatgtg tctaaaagtt gggaaaaccc cacgaatccg caacatcagc aagcatttgt
    27901 caatattcat gatgaagagt acggtgtaac agtcggaaac tttggtttga atgaatatga
    27961 agtaacagaa gacggacaaa tcgcagtgac gctacttcgc agtgtgggag aactaggcga
    28021 ttggggatat tttccaacac cagaagcaca gtgtctaggt gagcatcggt tcaattacag
    28081 cattgaacta catggaccag aagaaaaatt ctctacttat ttgcatgcat acgcagcaca
    28141 gattcctttt tccactcaac aaatcaaaca tcatgaagga acattgattt caaaacaaca
    28201 atatttaacg ataaaaagtg aaacgtttgc aattacagct ttgaaacgca gcaagtttag
    28261 tgataaagta gtagtaagag gtttcaatat gtctagtcat ttagaaaaat tggaaataac
    28321 taaagacaat ggaaaaactg tcatattgaa tctgcttgaa gaaccaacga agcaagcggt
    28381 tgtcccaata atccaacctt atgagattcg gacaatcgga ttcgaggagg aaaacgaatg
    28441 tatggcggaa tagaagcagg cggaacaaaa tttgtgtgtg cggtttcaga tggtggagaa
    28501 attttagaaa aattaagtat ccctaccaca acaccagaag aaacattgga tcaggtattt
    28561 gaattttttg atcgttatga attgaaggga atcgggattg gctcattcgg cccgattggt
    28621 atcgacaaaa caaaagataa ttacggatac gttttggcaa ctcccaaaaa agggtgggca
    28681 caattcgatt ttcttggcac aatcaaggaa cgctacaata ttcctgctgc ttggacaacg
    28741 gatgtcaatg ctgctgcata tggggaattg aagcaaggag cagcacaagg aaaaaatagt
    28801 tgtatttacc ttaccgtggg aacaggaatc ggtgcaggtg tcgtgatcaa tgaagaaatt
    28861 ttttcaggga tcgcacatcc tgaaatggga catatttggg tgaaacgcca tccagatgac
    28921 cattatgaag gtacttgtcc ttatcataaa gattgtttag aaggattagc agcaggaccg
    28981 tctattgagg cacgcacagg gatcaaaggg caagatctgc cgcaagatca tcctgtttgg
    29041 gctattcagg cttattatat tgctcaagca ctgatcaact atacgttgac gttagcacct
    29101 gaaaagatta ttttaggcgg tggggtaatg aatcaggatc atctccttca aaaaatccgt
    29161 cagcaatttg ttgaattgat gggtggttat atggaaacac ctcaagtaag tgaatatatc
    29221 gttcgttggg gactgccgaa tgaaagtggg attatcggta gtttgctgtt agcagaacac
    29281 gaacatcaaa agtaagcaga caaattacac aaaaagaaca gagtcttatc attatctgct
    29341 gataagactc tgttcttttt tatttctatt cccataatcc aggtaaagct ttaccgacta
    29401 ttttttcttg agtaaatgga tggatcatgt gcagttctaa tgcatggagc atcagtcgtt
    29461 cagctgttct attttggtag agagggtctc caacgatcgg atgtccctta tgagctaaat
    29521 gaactctgat ctggtgtgta cgtccggttt ccaaaacaca atagacttgt gtttgttcag
    29581 aaagtacttt gttgacagtg acatgtgtca aggcgctctg accattttta tcatctacga
    29641 ccctttttct ccgatcatgg cgatctcgtc caattttatt ggtgatggtc atatctttgg
    29701 caatttctcc ccatacgatg gcttgatatc tccgatagat cattttttgt tccaacattc
    29761 ttccaagtat cggcaagaca aatggatttt ttgcaaataa aacggcaccg cttgtttctt
    29821 tgtccaagcg gtggacaacg taaggtcgtt gctgtttagt gtcgagataa gcagctaaat
    29881 gattgagtaa ggtactgttt tctgtcggtt catttggatg agtcttcatt cctgcaggct
    29941 tatccactat aatcaaatgc tcatcttcat ataaaacacg gatgtgcttc gcatctccta
    30001 attgaacttc ttgataatta taatctgttt cttcgaataa caatgtgatc tggtcattgc
    30061 cctttacttc atgatggaac aaagcaggtt gttgattgat ccaaacgttt ttacgtatac
    30121 gcaaaaagtg tcgaaccttt ctaggaacta accattcctt ttcaagcaag tcgcgaattg
    30181 ttgtttcagg atggttcata ggtaaagtga tcgtgatttt cacaagtgta ctcctttcag
    30241 tgcaatcgca gactaattgt accattttta aaacatattt aagaaaaaac ttacattttt
    30301 ctgttcattc ttatgttact ctacttgcac taacgtaaaa aaacatattg aactacaact
    30361 taagcaggaa gaaaacactc tttcactatg gtaaaataag acgattgaat caaatagaca
    30421 ggagaagaag caaatggatt ttcaaagcat tttagaaaag ataaaagctg ctttgatcag
    30481 tttttggcgt tggatcagac catatctcgg acaattccat cgatggcgaa agcgcatctg
    30541 gaaaaaatat catgtgaaca aattgatttt gctgattggt ttgatctgtg tcttagtgac
    30601 aagtatctac ctctttattt tagcaaaaca agcaaatgtc gaaacgttaa aatcaggatt
    30661 aagccaatcg acagtcattt atgataagaa aaacgaagaa gctggcacac tgtacgccca
    30721 aaaaggaaca tatgtagaat taaacgcgat ttctccctat atccaagatg cagtaatctc
    30781 gacagaagat aggaattttt acgagcatca cgggtttgat atcaaaggga ttgcccgtgc
    30841 agcagtccga atggtcttgt ctggcggaac atcagggggc ggaggaagta cgatcactca
    30901 gcagcttgcc aaaaatgcgt atctgacatt agaccaaacg tttgatcgaa aagcgaagga
    30961 attatttttg gcaatcgaga tcgaaaagaa gtacagcaaa gaagaaatct tgaccatgta
    31021 tcttaacaat gcctattttg gcaacggggt atggggtgtc caagacgctt ccagaaagta
    31081 ttttggagta gatgcaacga atgttacgct gtctgaggct gctactttgg caggaatgct
    31141 gaaaggtcct ggtatttata atccgatcga tcacccaaaa aatgcgaatg atcggaaaaa
    31201 cacagtacta agtgtaatgg aagaaaacgg aaaaatcaca aaagaacaag aacaagcaga
    31261 aagccagaca gatatcagcg cgtatcttaa tgacacatac gataattcag attctggtta
    31321 tcgttatcct tattattttg atgcagtgat cgatgaagca gttaacgagt atggtcttga
    31381 tgaagaagat gtcatgaata aaggctataa aatctataca gctttagatc aggattatca
    31441 aaagcaatta gaagctactt atcaaaacag tgcattattc ccagcaaatg cttcagatgg
    31501 tgccatggtc caatctgctt cagtagcttt agatccgaat acaggtggtg tacaagcact
    31561 agtaggacga agaggagatc atgtctttag aggattcagc tttgctacac agatgcgtcg
    31621 ttcaccagga tcaacgatca aaccattaag cgtatataca ccagcactgg aagctggata
    31681 caagccttcc agtatcttga aagacgaacc gcaaagttat tacgatgcgc ataattttga
    31741 cgggacatac caaggagaag taccgatgta tcaagctgtt gcacaaagtt tgaatttgcc
    31801 tactgtatgg cttttgcatg agatcggttt acaaaaagga tatgataaag cagaagaatt
    31861 cggcctgcct ttagcaaaat ctgataagta ttatggctta gcccttggtg gactggaaaa
    31921 aggagtatct ccattgatca tggcgggtgc ttacagtgca tttgccaatg atggtcagat
    31981 gtatacgccg catcttatca cgaaaatcgt tgattcgact ggagcggtga tcgtcgataa
    32041 cacaaacaaa aaaccaaaac aggtcatatc aaaggaaaca gccgatgaaa tgaccagcat
    32101 gcttcttggt acattttcaa atggaacagc ggctgctgcg aatcctgcag gttatacgat
    32161 agcagggaaa acaggaacca cagaaactaa tttcgatgcc acaaaagcaa atgaccaatg
    32221 gatgatcggt tacacgccag acgtagtgat ttcgacatgg atgggttacg aagaatccag
    32281 caagctgcac tatttggaag ggacaagtgg aaatgttgtc gggaaagtct tcaaatcagc
    32341 ggcagaaggc atccttccgt atacttcaaa aacaggattt agtgtagcag atgcctatgc
    32401 cacaggagga caagtggtag ctgcagatca agttggaaac acaggaaatt ctaatggaga
    32461 gtctggaaat tggcaagata acttgaatca atatggtgaa caagcaaaag aagggctgaa
    32521 aaacttcggc gatatggtga aagaaggcgt tcagggaatt ggtgaagcgg ctaaagacct
    32581 ctggcggaaa tatcaaggag agtagcccct ttgaaaacga ataaccccat gttacaatag
    32641 agagtaacta ctaaaagaaa agagggcata acatgtcaaa catctacgat agcgcgaatc
    32701 aaatcgaacg tgagatccgt gaattaccag aattcaaagc gttgaaagaa gcgtacgaga
    32761 aagtacaagc aaacgaagaa gcacacaaac tgttcaaaga cttccaagcg atgcaaatcg
    32821 aattacaaga aaaacaaatg agtggacaag agttcagcga cgaagatgca atgaaagcac
    32881 aagaaatggc tgtgaaaatc caatcagaag aagtaatcaa tgacttgatg caaaaagagc
    32941 aaggcttcag tacaatcatc aatgacttga accgtatcat catgacacca gttcgcgacc
    33001 tttacagcga ataaaactat tttatgaaac aacagagggt gtgaaagaga cgttcggcct
    33061 tgagcgatga caaaattgct tcttattgcc gataggctgt ctcttgaaca ccatttacca
    33121 agaggtcgtg agcctaccgt ttaactctga gttacaagga acaatttcaa aaaacagctt
    33181 ctcatgtttg atgactattg tgacttgtga ccgaggagtt ggcaggagaa caccgtttat
    33241 tcagaaatag gagctacgac aaaagtcttg tcatagctcc tattttttgt cattcatttt
    33301 tcaagcggta gaaatagcct ttttgagcta acagtttttc gtaagtacct atttcaacga
    33361 tttttccttc atcgatcaca acgattttat ctgcctcttt gatcgttgaa agccgatgag
    33421 ccacaataaa agtagtgggt gtttctgtca ggtaattcag ggcttgctgg atttttttct
    33481 ctgactggtt atctaaagct gaggttgctt catctagcaa aatgattttt ggctgacgta
    33541 tcaacgctcg tgcaatggag atacgttgct tttggccacc agacagcttg ttgccatgtt
    33601 cgcctactaa ggtatccaga ccatcaggaa gctggtcaat cagtgaagaa agttgcgcag
    33661 cttcgatgac ttcatctaaa cgttcttttg atacgttttt caagccataa gtgatgttct
    33721 ctttgatcga agcggagaac aacaaagtgg tttgaggaac aacggctaaa taatttcgca
    33781 cacttcgcat atccagttca tccaaaggct gatcatctag aaaaattttt cctgaagtcg
    33841 gctggataaa tccaatcaat aagttaagga gtgtagattt tccagagcca gatggcccaa
    33901 caaaagcaat tgtttctcca gctttcacct ctagagaaaa atgatcgata atcggtttga
    33961 gtgagtccgg ataaagaaaa gaaacatcct caaaacgaaa atttccatcc aaatgttgga
    34021 tttttttctt accgtgataa gtttctacat cgccagcaat caacagttcg ccaatagaag
    34081 tgatagattc catgcctttt gaaatcgtag gaatcagcgt gatcattcca gaaacggaat
    34141 tgacgatcgt cgtgaaatac gtctgataca tcacgacatc gccgggttgg atgcgccctt
    34201 gtaaagctaa tatcccagtg aaaatcaaac aaatcagctg aaatatctga aaactagccc
    34261 agctgactga tccgaaaaca gattgcagga tatctaagtg gaatcctttt tcatagattt
    34321 gagtaaaatg cttatttaag cgagttgttt cgtgtttttc taacccatga gctcgagcaa
    34381 tcggtgctaa ttcgatcact tcgatcactt ttgcagaagt ctcttccatt tcttgcctga
    34441 agtctgagtt ggactgtctg atccttttac ggaaaaagag agtaacgaat gcggcgagag
    34501 gaacagtcaa taagaaaaac atgaaaacaa caggactttt ataaagcgtg atacctaaag
    34561 ctacgaataa attgacagcg atatttaatc cgctgacaaa tacttgagag gacaacgttt
    34621 ggatagcttc tacatcacgg atgatctttg actggattcg tccagattgc aattcttttt
    34681 gataaggaat agatagttct tggattttct tgataagggt cgctcttagt ccagcttcta
    34741 cttgacggat cgaagtgcta tggtatttta catgaaaata attcgtcaat atattttgac
    34801 caatcagaca agccatcaaa aaagcgttga aataaatggc ctgcaactga gaagaatctt
    34861 tcgatgaagc tgcattgatt acattggcaa tagcgatcgg cattaaccaa gatggaagat
    34921 gtttgataat aaaaaagagt cctgacatgg caaaacgcca ataatttccc tgataaagat
    34981 gcagcaatgt ctgaaaagca tttgcatgat atttttgata acttttctgt attcgttcct
    35041 ccataatctt ctccttaaca atcttggtaa ataaactgca agtgttctat tgcttcagga
    35101 acataaatct caggagtagc ttcaagagtg gcgtacatta gaggacgctc atatttgata
    35161 taatgcagta ccgggcggaa atctaaacag cccttgccaa caggtaccat gcggatcttt
    35221 ccattttcca tgatatagtc tttgagatga agcgctgtaa tataaccatg taaattgtcc
    35281 aaggcacctc ggatcacttt ttcctgatca gcatgatttt ctttatgcat caaattcgca
    35341 caatctaaaa tgatttttaa atttggtgaa gctacttcat cgattaaacg tttagctaac
    35401 tgatagttat agattggatg attgatccct gcttcaacag caacagttac gccaaaattt
    35461 tctgcatgag cgactaattc aatgatagaa tttctggcga tctgataagc ttcttcagta
    35521 aaattttctt ttgtgtaacc gacagagaca ctaccggttt ccgtagcaat catcttggct
    35581 tgataggcag agcacagagc aatttgctgt ttgaaagttg ccaatgcttg tgcacgaact
    35641 tcttgatttt tgctggatag gttgatatag catcctaaaa tggaaagttc gatattgttt
    35701 ttttggaagt attcaccaaa ataggcagca ctcccaagtg tcatgtcagt taatttaagt
    35761 tgttcaggaa atgctttttg tggtgcaaat tggatatggg acaagtgaag ctgtgatact
    35821 ttttgaacga tttcttcacg atttcgaaca tctaaatcgt gggcacggat gcctaaattt
    35881 aatggaaaca tctcaaactc ctttttgtaa ataattagca agaggcagac gggattcttt
    35941 tatcaattca acaattattc gggcaacttt atcagcgcct tctggactaa agtgggtatt
    36001 gtcttttagt ccttctgggt aatttttaca agtatcaggt ataagatgca ggtagaattt
    36061 ttttgtctct tcttttgaga aggtctggaa caattcttgt gatcttgaga acacatctaa
    36121 aagaggaata tggtgtttct cagcaaatgc acgcatcgct tttggatagt ctccaagtat
    36181 atctggattc aatgttccgt tttctaagta atctcgtcgc gtcacagatg tcagtaagac
    36241 catttggacg ttcgcttttt ttgcgcattc aaaaaatatc tgcagatttt ttaaatagct
    36301 accgaaggga agcgtacctc tttcttcttg gattttctgg tcgttatgtc caaattgtac
    36361 aaataagaaa tcattcggct gaaactgtga agctagacgg gctaaccttc cttcctggat
    36421 aaatgatttg gtgctgcgtc cattctttgc ttggttattg atctggatct cgggtgaaaa
    36481 ataagcagag attttttctc cccaacctgt ctcgggacgc ttgttttcat ctttttctgc
    36541 cgcagtagaa tcaccggcaa tatggatagt aggcatgtta tctcttcttt cataaaggtt
    36601 tataggcaat gaagcagaac agcaagagaa gaagacggag caaatttggt ccgtcttctt
    36661 ctctaaaacg tggataaacg gattccgtta tttcactatc ctgtttttga ttcgttactg
    36721 ttactattaa tcaattaggc aaaaaagcca aagtaatttt tagcatttgt ataactaatc
    36781 gcttgaacta gacttcctaa aagttgttca tcttcaggtg cttctcctcg catgaccatt
    36841 tcgcctaaaa attcacaaag aacacgacgg aaatattcat gtctagtgta ggacaggaaa
    36901 cttcttgaat ctgtcagcat gccgacaaaa ttccccaaag cactaccatc agcaaattgt
    36961 gtcaattgat cgcgcatacc agctcgagta tcgttgtacc accatccaga acctaactgc
    37021 agttttccat tctgttcttt ttggaaacag cccatcaaag ctaaaatcgc aggatagtca
    37081 ttcggattca atgaataaag gatcgtcttt ggcaactgat ccgtttcttc tgcacggttc
    37141 aataattttt gcagaggaat agtcaaagaa agatcattca ttccatcata gccggtatcg
    37201 ggccctaatt tttccaacat ttgtgtatta cagttacgat aagcatggat gtgcagctgc
    37261 atcgtccaat tatgagaatg atagaagtgg gtcaaatgta tcagtgtttc tgtacgataa
    37321 gcatcgattt catctgaaga taatagtttg ttagctcgtg ctttttgaaa aatctcttct
    37381 aatactgttt catccgcttc tttatagcgt aagatgtcta aagcgtggtc ggaaacacga
    37441 catccatgtt gatggaagta ttctatccgc tgccctaaga cttctatcag ttcttgatag
    37501 gtggtgatcg tttggtcagc tgcttcttcc agtagtgtga cccatgcatt aaatccttct
    37561 ttttcaatat tgagtgcttt atctggacgg aatgaaggta gaaccttcaa atctggttct
    37621 tcatgagcaa gcaactgatg atagtgcaag tcgtctgcgg gatcatctgt tgtacaaatc
    37681 acttctacat tcgatttttt tgcgatttcc cgacggcgaa aatcaggagc tgccaaaatt
    37741 tcatttgctt gtgtccaaat tttctctgca ttttcttcat ttatcaacaa gtcaataccg
    37801 aagaaacgct tcaattcaag atgtgaccaa ctgtaaagcg gatttccgat aatttttggt
    37861 acggtttgac accaagctaa aaatttttca aaatcagaag catttcctgt gattttttct
    37921 tcaggcacgc cgcaagctcg catcaagcgc catttgtaat gatcgcctcc taaccaagct
    37981 tctgtcagat tgctgaaatt gttgttttcg taaatttctt ttggatctaa gtgacagtga
    38041 taatcaataa tgggcatgtt ttttgcgtag gaatggtaaa gctttttcgc ccaatcgtct
    38101 tttaataaaa aatcatcaga taaaaacata aatcttcctt ctttcttttt atactgtttt
    38161 atgaaaatca aagtgttact ccgtttttaa aaatggcaat ttctcgaacg tcattttgtt
    38221 catttttcgt ttcttctcca ctagctacag cgatgatttt ttgaacaaac gattctaaga
    38281 ttacttccat tggttgttct aataagacgc ctgcattaaa atccatccaa tgacctttgc
    38341 gttcaaaaag agttgtattc gtagatacct tgaccgttgg gacatatgag ccaaacggag
    38401 tccctcttcc tgtggtaaac aagaccaact ggcaatcgga tgaagcaaga gcagaggcag
    38461 ctacaagatc attcccggga gcttgcaata aactaagccc tggttttctg attttttcgc
    38521 catattgtag cacatcaacg acaggagagc ttcctgattt ttgcgtgcag cctaaagact
    38581 tatcttctaa tgtagtgatc ccacctgctt tattaccagg agatgggttt tcgtaaactg
    38641 gttccccgta agacaagaaa tactgtttga agtcattgat caagtcaacg attgagtcaa
    38701 aaacttcttc attttccgct cgtgccatca atacttgttc tgcgccaaac atttctggca
    38761 cttctgttaa gatcgtgctg cctccttgag caatcaagta gtcagaaaat gcaccaagta
    38821 aaggattagc agttattccc gatagaccat cagaaccgcc gcatttcaaa ccgacattca
    38881 acttagagag cgggactgat atgcgctggt cattttccgc cgctgttaaa agctcttcta
    38941 atagagccac accttgttcg atctcatcgt aaacatcttg agccactaga aatttcactc
    39001 gttcttcatc atattcacct aaaatttttt tgaattcagg aactgtattg ttctcacaac
    39061 ctaatccaaa tactaaaact cctccggcat tgggatgatt tactgcgtcc gctaaaattt
    39121 ctcgagtatt ttgatgatct tttccaagct gcgaacagcc ataaggatgc tttaaaatcg
    39181 taatatggtc aaactgtccc agatctggat gtttttcctt gaactgtttg acgatcagtt
    39241 cagcaatgcc attcacacac ccaacggtag gtactaaaaa caaatcatta cgaatcccta
    39301 cttttccatt ttttcgcaag taaccttgaa atgttcggtt ctcaaaaagg taatgacttg
    39361 gatggacatc tttttcatat cgataatcca attcaccaga aagattggtt tttacattat
    39421 gagtgtgcag ccattgaccg gcagttacgt ctgtcgtcac atgaccgatt ggatagccat
    39481 atttgatcac gttgtctcca gctttcaaat cacccaatgc aatcttatga ccttgcggga
    39541 tatcttcaag agtggtgatc gtttgctgat caatcgtcag ttgtgtttgt tttggaatag
    39601 gggttaatgc gacgaccaca ctgtctcgtc gatttaattt cattgttggt tgcagggttt
    39661 caagcatgga ccatcgttcc tttcatttct tgtaatactg accggacacc tttttgatcg
    39721 atctttgcag ctatttcttg aactgtatct gtcacattcg gtatttgaga caaatcttct
    39781 ccccaaagcg cagcgttttg caataatcga ggaatagctg ttccattatc agaccaagca
    39841 tcagtaaatt cgcttatcgt cttttcatca tcatgtggct ttacttgatc gcctcgatac
    39901 ataagaagta gcgcagctag tgaaacagtg attaacggtg gtacctgatt ttgttcttcg
    39961 atatacttct tgaacactgg aagcagacgg gtgctgaact ttgaaacact atttaatgaa
    40021 atcgcttcta atttgtgatg ggcaaaagga ttcaagaaac gttctttgat ttggtcagca
    40081 taaatggcta attcatcttt aggtaaagaa agcataggaa tcaattctag attgaataac
    40141 tgatcaacat atgcggagaa taaaggatct ttcattactt cttctacagt ttccaattcc
    40201 gccaacaaag caagagggac catcgctgta tgcggtccat taagcaaatg caccttacgt
    40261 tcacgataag gagtcatatc atctgtgatg atgacattca agccagcctg tttgaatggt
    40321 agttgattct ccaattcttt aggcccttcg atcacccaaa gcatgaatgg ttctgctttg
    40381 accatcaatt gatcttcata gttatgccgt tgattgaaaa cacctgcatc ttcgcgagga
    40441 taacctggga cgatgcgatc aactaaacta caacagaaaa cattttcttt ttctaaccac
    40501 tcaacaaaag caggttctaa atcccatttt tctgcgtagc gtaaaatgat ttcttttaga
    40561 cgttcgccgt ttctgtcaat cagttcgcaa ggaatgatgg taaagccagc tttgtttaat
    40621 ttgaaacgtc ggtataaaaa ggctgtcagt ttgcccggga agctctgtgg gggagtatct
    40681 gttaaattat cagtctccac gaattggatt cctgcctctg ttgtattgga gacgatatag
    40741 gccaagtcgt cattttctgc tagagataga taagcatccc attcatcata aggattgatc
    40801 atttgttcta ctacggtgat aatctcggaa gtatcaacga tttcgccatt gctgagtcct
    40861 tgtaaaatga ccgtatataa attatcttgc tggttcatca tatttccaag accttgttct
    40921 aaaggttgaa tgattgcaac attaccttta aacaattgtt ggttattcag ctgctgaatc
    40981 tgccaatcaa taaatccacg cataaaattg ccttcaccaa actgaagaac ttttacaggt
    41041 gcttcgtttt ttttcactaa ttcttttgtc agttttttca tataaacttc ctttctgtgt
    41101 tatgcacacg ttaacatttt tatataaaat tacttgtagt ttacaagtaa ttgatcgact
    41161 cacgaaggat caacaaggtg gagagctcaa ttttagattg ttcgatcgtc ctgccttcga
    41221 tcaaatctag taaaagcttt gttccttctt gacacatttc tttcaaaggc ttacgtacgg
    41281 tggtaagcgg cggattgaga taggagacga ctggagaatc atcgaacccg atcagagaaa
    41341 tgttctgggg aacacggagg ccagctaaat gtacagctct caatgcacca atcgctatgt
    41401 cgtcgttgcc gcaaaaaacc agagtaggca ggtcagaaag tgataatagg tattccatgt
    41461 tttggaggcc gctttctaag ctgtaatctc ctgttaaaaa ataggctgga ttgacaggga
    41521 tgctcgcttt ttttagactt ttcaataccc ctttttcccg ttcttttgtc gaacgaaaat
    41581 ttttctttcc gccaatataa gcgatcttcg tatgtccgca tccaataccg taatctactg
    41641 cctgcataac accggccgca tcatcggcag tgacgttgat aaccgctgga tcattgatgt
    41701 gacgattgac aacaacgaaa ggaaattctt tttctttgag atagtcgatg aaaggctgat
    41761 catcatcact ttgactcata acgatcagtc catcgtagcg ttgcaggttg atttctgtta
    41821 aatcaacaac atcgatactt tcaacagata aactgtaatt tgtgtctaat actgaatgga
    41881 tgcctgcaat ggaatctgct aggaaatttg atgaagttcc tttatgcaaa cttgagaaaa
    41941 atagtccgat tagatatttt ttttgattca ctaaaccttt tgcactatag tttggcgaat
    42001 aattcatttc cttagctagt tgtcgtattt tttgttttgt ttcatttttt attaaactgc
    42061 tgttattcaa agcacgagaa actgtcgtat gagaaacgcc agctgcttta gcgatatctt
    42121 tgatcgttac cattccatca ttttccttac tttttcactt tttgttaacg cattcatcat
    42181 attacgataa ctacgataag tcaatagatc tttgatatga aaagattgca cacgttaaaa
    42241 attacttgga tttttatttt taattatgct attcttgaaa gcggggaatg ctcatttaat
    42301 tagatgagta tcaattttac agaaaaatga aagcctttta ttttaaaagg aggagaggaa
    42361 gaaaatgaag aaaagtacag tattttataa aatattttta ccgatgtttt tattaggagc
    42421 cgtacttgtc ataggattta gtttattcat ttaccagaat acctatgaat cgatcgaatc
    42481 gagttattta acagacaaaa agaatttgct caggcaagtt aaaactaacg ttgaatggaa
    42541 aattagaacg attgaatatt cgttttctac gtatggttcg accaaaaatt tctcggacat
    42601 attcaagcat ccgctgacat atacagatta ctccacttat tctgaaatca ggaaagaact
    42661 aaattttata gaaacgattg ttatggatga taataattat gatttagtca gtttggctgg
    42721 taaatgggga gtaatcaatg gatcgttgag tcaactgacc gaagaggaag ttgaaaagta
    42781 tcaacagaag tacataaata acaaaaataa tttattttgg caaaagaaaa acaaaggaat
    42841 cgaaatggtg atttctttgc caatgtttga aaaagaaaaa tatgcattgg gaattgctac
    42901 gatagagaaa catacaatag aacaagttgt tggtgaaagt ggagaagaca tactttctat
    42961 tgaaaacgaa gttggcaacc tttttactac tcagacagta aaaaataaag agcaaccaac
    43021 tgtattaacg gacgtggatc tagattacaa tcagctgaaa gtgataagag aaaaagataa
    43081 aacgtatata gtactgaaat cagattataa taattggatt tacagattag aagttgactc
    43141 tagtgcaatt ggcgcaatga tccgcaatct gagaatcggg ctagttgcag tgtctttaac
    43201 actggtagga ctcattggtc ttctttccta cttattttcg gacagatttg cccgtccgat
    43261 ttctcaaata caggaacgtc tgaatcttaa atcaaaagga ttcagtggga aagaactaga
    43321 tttggtcgct caatcagtca gtcggatcat aggagaaaaa gaagcgttaa gtgcacactt
    43381 agttacccaa aagccacagc tggaaacgct atttgtactt agtttattta gaaatcgagt
    43441 agaaaggcga gaactagatc agcggttgca gcaatttggt tatagttctc aaaatgactg
    43501 ctattataca gctttggttc aaatcgatct gttagaagat agtcacggtg gggagcgtga
    43561 tttgctactt ttagcgatca acaacatgat cacggaaatt gtgccaaagg aaaatcgaat
    43621 gctgccgatc gttttgaatg aagaaatgca agccactatt tatcgaatgg ataaagatga
    43681 tgcagaagca agcaaaaaag tcatggagta ttgccgactc attcaaaaac gtgtaaaaga
    43741 atacttgaat ttaactatca gtataggcat cagtaaccgg ttcgaaacgc tgaatgaaag
    43801 caagcaatcg gttgatcggg caaaagaagc cctgtattat cgtgtaaata ctggtccaag
    43861 ttcaattatt ttttatcagg aaatcgttcc tgctgctcat gaaaaaacac ttattagata
    43921 tccgatagaa gaacaaaatc gattgtttga agccattcgt tctggaaatc aggaagtgaa
    43981 gaatttagta catgaattga ttgatgcatt gtttgcacaa aataaaaatc ctttgagtcg
    44041 ggaagtagtt tcggtccgct tgatcaatga actcgttcaa ttaggacagt tattgggagt
    44101 agattcaaaa aactttgata acatgaaaca aatttatgta aaagcactga acaattatca
    44161 tcccaaagaa ctagaaaaac ttgttttaga acaattagtt ctgccaatca cagaatgctc
    44221 tcaagcaatc actgatcatg aatttaaaaa tttgtcggag aatattatgc atatcgtcta
    44281 cacagaatat gatcgtgatc tgtctttaga tgtgatcgct gataggttgc attataaccc
    44341 taactattta agtaatgtat ttaaaaagga aacaggagaa aaatttggtg attttgttca
    44401 aaatcatcgt ttagaggtag caaaaaaatg gttgaaagag actaacctct ccgtaaaaga
    44461 gattgcagaa agattgcaat atcgaaatcc gcaaaatttt attcgtttct ttaaaaagaa
    44521 ggaatcgatt acgccgggag aatatcgaaa aaaatatttg tgaatcaaga ggctgttttt
    44581 cttgtggact gattcaagca ataaaagaag ttagaataac cctagtattt gtatttatgg
    44641 atagttaaat ttcaaggcta agcacgcaaa aagaactgtg acaaaagtct tgtcacagtt
    44701 cttttttacg aataaatggc gttcaagaga caggctatcg acaataaggc ataattttgt
    44761 gaaatatggg aagctatttt tcaaaatcgc ttcttattgc tcctgtgggt tactcgtcgc
    44821 aatgtttgtg agagttttta tcatcgctca aggctgaacg tctctttcac aacctctgat
    44881 acacggtgtt ccaggagtag attcttcgaa aaataagccg aaatttcaca aaaatttaag
    44941 aagcaatttt cgtaaatgcc ttcttatttc ttgaagctga ccacttctga cacaactacc
    45001 attttgcgtt cagtacataa tcaccctttg acagaaccta cgagtgctcc tttgacaaaa
    45061 tatttctgaa caaaaggata aacaatcagc ataggcactg ttgcaataac gataacagcc
    45121 attttaactg tttgtgctgg tggaatcaca tcaacggcac tactttctgc ttgcatccca
    45181 cttgatacaa tgacgatttg gcgtaaaaga atctgtatcg gccatttaga tgaatcgttg
    45241 atatacaaaa tagcagtcat ataagtgttc cagtaagtaa cagcataaaa aagcgagata
    45301 gtagcaatag acggtaacgc taatggcagc ataattttga aaaatacacc aaaatctgtg
    45361 caaccatcca tttttgctga ttcttccaaa ctatccggca aggcttggaa aaagtttctc
    45421 ataatgatca tattcattgc attaacagcc acaggcagga tcatggccca gtaagaattg
    45481 accagcccta gagaacgaac aactaagaac gttggaatca tccccccgct gaacaacata
    45541 gaaaatacaa caagaaagtt gacgaaacct cgaccaaaca aatactttct ggaaagaccg
    45601 taggccatca gtgaagttgc acacatactg acgatcgttc cgacacctgt aacaccaatc
    45661 gaaacagcaa gtgctctaaa aatggtcggc gtagaaagaa tgtagcgata cgcgtctaaa
    45721 gaaaaggtag taggaaaaag gataaacttt ttcgcgacga cttcttgtgt agaagcaaaa
    45781 gatgtagcga tgatatttaa aaaaggaacg atacagatca aagctagcaa aattagaaac
    45841 gtattgttga aaagtgtaaa acttctttct cctatagaga ctttcttttt catatagata
    45901 ggctcctcct caaaataaat taaatgtttc tgtttctata tgttcaattt atcatcggtg
    45961 aaagattacg tatataatca tttcctatgc taagtgtcag atagaaaaaa atagaaggtt
    46021 tgctatgcgt agtttatttg tgaaaaaata cactttatcg ttttgtatag cacaaaaatc
    46081 attgctatgt aagcgttttt acttacggta aaaatgatta tatacgtaat tcagatagtt
    46141 atctatcatg aagtcataag cagcaaacat tcacaaaact aaggaggggc ttatggaaag
    46201 tgtaaagaaa caagaaccat ttcaactgac gctatcgaaa aaagaagaaa agctcagaag
    46261 acgaaaaaaa ataattgcag gaatcaaaac gaataaattt ttatatgtga tgattctgcc
    46321 gggagtcctt tatttcttga tttttaggta tcttcctatg gggggactcg ttattgcttt
    46381 tcaagattat caaccatttt taggaataat gggaagtcct tgggtcggtt tcaaacattt
    46441 cattcgtttg tttacagaac cgacattctt tacattatta agaaatacgt tgatcttgtt
    46501 cggattaaat atcttcgtgt tttttccgat gccaatcatt ttgtctttac tattaaatga
    46561 agtaacgaac aaacgattga aaaacgggat tcaaacgatc atttacatcc ctcacttcat
    46621 gtcttgggta atcattgttt cgattactta tgtatttttg aatgttgacg gaggggtatt
    46681 gaatgaattc cttgcaacaa tgggatttga aaaaatcagt tttctaacat cccctgaatg
    46741 gacacgcaca gtatatatcg gacaagtgat ctggaaagag ttgggctggt ctacgatcat
    46801 ctacctttca gcgataactg cagtcgatac acagttgtat gaagctgcag aaatggatgg
    46861 agcaggacgc ttacgcaaaa catggcatgt tacattgccg gcaattcgtc cagtaatcat
    46921 taccttgctg attctaaaaa tcggtcagac attagactta gggttcgagc atatgtactt
    46981 gttattgaat tcattgaatc gaagcgttgc agaaattttc gacacctata tttatacagc
    47041 tggattgaag aatggacagt taagtttcag tacagcaatg ggattgttta aaggggtcgt
    47101 aggattgttt atggtaattt tagctaataa gattgccaaa aagctaggag aagacggcgt
    47161 ttactaagat agaaagagag ggaaagatat gctgcagtca ttagataaaa taaacggaag
    47221 gctaaatcgt attttacagt tggtttattt gaattttctg tggggcggtt tagtcatcgc
    47281 aggtttggga gtttttactt tcggtcctgc atcgtatgcg atggttgcag tgattagaaa
    47341 atggctgcgc tcaaaagaaa cgtttccttt gacgaaaacg tacttcacat attttaaaga
    47401 aaactatcgt gaaaccttgc tgatgagctg gatatatggc gccatcggga ttgttttact
    47461 tgtggatctt tctttcatac acaattggta tcttaggatc gctttgtata ttgctgcgtt
    47521 catatatgtg ctctcagcac tctatatttt cccaatcatg gctcattatg attggaaagg
    47581 atattttttc aaaatgaaaa tggcattttt attcggattc tcacatcttc attactcatt
    47641 agtgttgata ttaagtatgg tagggattta tctgatgatc atccaaacaa tgccaggtgt
    47701 tttaaccttt atcggtggca gtctcttctt ttccgcagtc acgtggacag caaattctat
    47761 attttgccat ttggaatgga agaactcata tacagaaaaa acagaagaaa acaaaaatat
    47821 tattaaaaca gtgaaggaga aaatttatga aaaaagcaac gctcgtaaaa ttaggtctta
    47881 gttttgcagg aattctagca cttgccgcat gcggcagcag ttcaagtaac agttcttcag
    47941 agacagaaga tggaaaagct aaaatcactt ggttaaatat tttgcatcat gcttcaccgc
    48001 ctacagacac gattgtgaac ttgatcgaag aaaaaaccga tacggaactg acattcaact
    48061 ggattcctga tgcttcaaaa gaagaaagat taacaactgc attggcttct gatgaactag
    48121 gagatatcgt tacacttcaa attgcgatgt tgaaaaactc ttctgtccgc aatgcgttaa
    48181 aatcaggcgt attctgggat gtatcagaat atttaaaaga ctataaaaat ttaagtcaaa
    48241 tttctgaaga tagaatcgaa gctgcgagta tcgacggtgc cttgtacggc gtaccgatac
    48301 aaaaagacta cgctcgtgct ggcttagtca ttcgaaaaga ctggttggat aatctaggac
    48361 tagatgttcc aactaccatg gatgagcttt atgaagtagc taaacaattt acagaaaacg
    48421 atcctgatgg aaatggtgtg gacgacacag ttggttttgg cgatcgtgcg cctagtgata
    48481 ttcgttatac cagctttaaa cttttcactt cttattttgg agcaccaaat ggctgggctg
    48541 tagacgataa tggcaaattc actccagaat ttgatacaga agagtatatg aaagctttga
    48601 atttttcaag agatctattt gagaatggct atttggcaca agactttgca gttacccaaa
    48661 agactgatca gcaagaacaa tttgcacaag gaagaactgg aatctacact ggaatggtgg
    48721 atatcaagaa tctgaagacg atgggtcaag gtattcaaga tgatatggaa ttagtgcctg
    48781 taaacaagat ctcagatggt gaaggcggcg gttatcatgt ttggtcagaa ggaaatggta
    48841 ttggcggctt gctagcattt cccaaatctc aagtaaaaga cgaagcacaa ttgaagaaat
    48901 tacttcaatt tgttgatgat cttttagaag aagatgtgta taaattgatg actggcggta
    48961 tcgaaggaac gcattatgaa ttgaatgatg atggttctat cgaatttatc gatatggatc
    49021 tttggcaaca agaggtgcaa ccgttatcaa gctctcgtcc tagtgaagtg acgttctctt
    49081 tcaaagatac agaccctgaa aaagaattct ctaatcaatt gatcaaagaa aatgaagaat
    49141 ttgctgtaat ggatccttct gtgccattgg attcaccgac gaacaatgaa gtaggatcag
    49201 aaattgaaaa aatcgtcatt gatgctacgg tgcaatacat catgggacag cttgacgaag
    49261 atggattcaa aaaagctgta gaagactgga aagcacaagg aggcgatcga atcacacaag
    49321 agtacgagga agcatacaaa gcagcggcac agtaatatag acgattggga caaatacttc
    49381 ttggtatttg tcccaaatcc tattttaatt tttaaaggag agcaaataat ggaaaactgg
    49441 tcaaagaaat tagcaaaaag tatcatggaa agaacacctc gcttatatga agaaaagtgg
    49501 tataaaggaa aatggtctta tgactatggc gtcgtactta aagggttcca attactttgg
    49561 gaacgaaccc aagaaaaaat ttattttgat ttcataaaag acaatatcga ctatttcgtg
    49621 caagaagatg gaacgatccg tggctacagc gttgaagaat acaatatcga ccatgtaaat
    49681 acaggaaagc ttttcttttt attgtacaaa gaaacaggcg aagaaaaata taaaaaagca
    49741 gcagaactcc tttcccagca gttggcaaac catccacgca catccgaagg agctttttgg
    49801 cataaagaaa tttatcctta tcaaatttgg ttggatggct tatatatggg ttctcctttt
    49861 tatgctgaat ttatccagaa ttttagtgaa gaaaaagatt accaagatgt tttgagacag
    49921 tttgaaatca gttataaaca tctattcgat ccaaaaacaa atttgctgat tcatgcatgg
    49981 gatgaaaaga aggtccaacc atgggctgat ccaaaaacag gtctatccca tcatttttgg
    50041 agccgatcga ttggctggta tttgatggct gcagcagata cctatgaatt acttcatgaa
    50101 gaaacagatt gttctttgct gaaagaaatt ctagaaaaga cactggctgc attacttcca
    50161 tatcaagaag aaaacagcgg gacatggtat caagtaacaa cagaaacaaa acggaaagga
    50221 aattatctgg aagcttccgg cagtagtatg tttgtttacg caatggctaa aggaatacgt
    50281 ttgggactgc tgaacaaaga agaatggctt ccacaagtga agaaatcaca tcaaggatta
    50341 cttgatgaat ttgttctgga aacaaaagaa ggctggctga acttgaataa aaactgtcaa
    50401 gtagcagggt taggcggagc agatcagcga gatggttcat atgcttacta catcagtgaa
    50461 ccaattattt gtaatgatca aaaaggcgtt ggtgcattct tgcaagcatt gattgaagtg
    50521 gaggcattat aaatatgtat gatattttga catttggcgc atcaattgat gaattgaata
    50581 ctgaagcaat acaacaagcc attgatgctg cagcaagtga cggaggcggg accgtagttg
    50641 ttccagcagg tgaatttcta acaggagctt tatttttaaa aagcaatgtc gaacttcatt
    50701 taagcgcagg agcggttctg aaattctctg acgatccaaa agattatcct gttgttcatt
    50761 cacgttggga aggagtccat cgaaaagttt atgcttcctg tatctatgct caaaatgtag
    50821 agaacatctc tgtcactggt ttcggtacat tagatggaaa tggaaaaaaa tggtggcata
    50881 cttttagaaa tgaaccagat aatctcgctt atcctcgtcc taaattgatg agtttccata
    50941 actgtcatcg aattactgtg aaagatatta aattgatcca gtcaccaagt tggacgatca
    51001 acccgattct ttgcagtaat gcaacgtttg ataacttgac gatcttgaac ccagcggatt
    51061 caccaaatac agacggaatt gatccagaat catgcaaaaa tgtgcgtatt agtaattgcc
    51121 atattgacgt gggagatgac tgtattgcaa tcaaggcagg gactgaagat acgtacgaaa
    51181 ggatcgcttg cgaaaatatc acgatcacaa attgcacgat ggtccatgga catggcggtg
    51241 tcgtattagg aagtgaaatg agtggtagta ttcgtaatat taccatttca aattgtatct
    51301 tccaagaaac tgatcgagga atacgattga aatctagacg aggtcgaggc gggatcgttg
    51361 aagatattcg agtatccaat atagtcatgg ataatgtgat gtgtccattt atactgaatc
    51421 tttattattt ctgtggtccg cgagggaaag aaccgtatgt atgggaaaaa aaggcttatc
    51481 cgatagatga acggacacca gcattcagaa ggatccattt ttcgaatatc acggcaagga
    51541 atgtccatgc ttctgcaggt tttatttatg gattagcgga acaattcata caagaaatca
    51601 catttgacaa tatcgatgtc tcgatggccc aagatgcagt tcccggtgtt cctgctatga
    51661 tgacaggaat agaggaaatg agcagacaag gattttatat tggctttgcg ggtaaggttt
    51721 cctttaacca gatgtcgatt gaaaatcacg agggaccagc atttctatta gaaaatacta
    51781 aagaaatcag tattgagaaa ttccaatcaa atcaatcaga aaatatggat gaactggttg
    51841 ttcgtaaaaa ctttgcttat gcagttgaat gattttttag gtgctccatc tagcagacat
    51901 acccctagtg gaaaacgatt ataccgagaa aaacaaaacg gttttatgct tgaatactat
    51961 caattgtact taaatgaatt ggaaacagta ccagccctct atgcttatcc agaaaaagaa
    52021 ggaccgtttc cgccggtcct ttacctgcat tctcacggcg gagatttttc agtcgggaaa
    52081 agtgaattga tccatggtgc tccttactta gcttctccat cttttgcaga agtactgaca
    52141 ggaatgggat atgctgtttg gtcgattgat gcttggggat ttgaagaacg cggaggtatt
    52201 tctgaaagcg agttgttcaa acaattttta ttaacaggaa aaacgttatg gggaatgcgt
    52261 atttatgatg tgatcagctt gatcgattat ttggagacaa gggaagacac agatactcaa
    52321 cggctcgcaa cgattggtct ttctatggga ggcttattaa gctggtgggt gacagcattg
    52381 gattctcgtg tcaaagtttg tattgatcta gcggcacagg tggacatcga aatacttttg
    52441 ctacatcgcc gcctagatca tcatgggttt tattactatg tgccaaatct attgacagct
    52501 tatacaacgt tagcaatcca agaaaaaatc gctccgcgcc ctcgtcttag cttagttgga
    52561 aaaaacgata cgatgtgctt ggacgaaggc gtactgaagc tgagaaaagg gctggacaaa
    52621 aagtatcaat caatgggtag tccagaaaac ttttcttctt tttctttaac aggcggtcat
    52681 atggaaacac aagaaatgag aaatatttgg aaacaattca taagggagca tttatgagga
    52741 tgaaagacaa actgataatt ggaaagaatg ctatagatac cccgacggat tttgaaacta
    52801 tccaagaagg aatcgattat ttggcaggcc tgccggatag ccatccaaag gtcttgatag
    52861 taaaagaagg aagatatgat gaatatatag aaagcagatt atccaatttt aaacttgtgg
    52921 gagcaggaac agtagttatc tccggtaatc gttttgcaaa acaggagtat cttgacggta
    52981 gccagttagg gactttccga agtgctactt ttttcttaga aggatcgaat gtcgtattag
    53041 aaaatcttca catcgaaaat acagcaggtc caggagaaaa ggtaggacag gctgttgctt
    53101 tattcaattc aggagatcgc gtatctttaa aaaactgtcg actatctggt tatcaggata
    53161 ccttatgcac gggtccgttg cctgatttgc aaaaagatgg tactcctttt tgtacaccgg
    53221 cttctgccaa tcctgagtat tgtcgtcaga cctatgaata ttgctggatt gaaggaacgg
    53281 tggatttcat atttggtggg gcagatgccg tttttcatca gtgtcatatc catagcttag
    53341 ccagtaaaaa tcctggatac atcacagcag catctacgcc gaaaaatcaa aaaacagggt
    53401 atcgttttga aagctgtacc ttgactgcag aacctgatac tagaaacgtc tatttaggaa
    53461 gaccgtggcg tccgtatgca aatgtcttat ttgaagcgtg taagataggt gggcatgttc
    53521 acccaactgg ttgggataat tgggatgaca agaaaaatga acagactgtc aaattctctg
    53581 aacgtaataa caattatgaa acatcgatca aaagacctga atggatacat ttagaaaagc
    53641 agggggttca gaaatgaaaa gaaaatggga actattgcta ggaatggtcg gtggcagtct
    53701 atctttgatt ttctttggcg ggttagcagt tactttaagt aatatgtctg cgtcagagtt
    53761 taaaaaaagt tatcagtcgc ttgctgtaga tcattcaact ttgtctttag aaaatacatt
    53821 tggattatta caggacatga ctggtctgtt tgccgttgtg ttgtttattt cacttgcttt
    53881 tttagcagta gcattgtttt tgactgctaa aggaaaatac ttaacaactg ccactggttt
    53941 gtattttata acaggattca tattgttgat tggcactcag tttattgcgt ttccttttgc
    54001 atttttttat ttcgcagctg gggcattcag tttatatcga gtaagaatga gaaaaggagc
    54061 ctgaatcatg cagactatca aagtgaaaaa tcctatttta agaggattca atccagatcc
    54121 taatatatta agagtgaaag agcggtatta cattattgtc tcctcttttg aatggcttcc
    54181 aggaatccga gtatatgagt cgaaaaattt agtcaactgg tcacatacaa cggatatttt
    54241 gaccactcaa gtatctttgc aaggaaatcc tacaaatgga agtatatggg cgccacaaat
    54301 cagttatgct gatggattgt tttatcttgt ttacacagat gtcaaaagtg caggccgtcc
    54361 gtttaaagat gtccacaatt atttgatcac tgcatctgag atcacaggtc cttggtccga
    54421 accaatttat ttaaatagta acggctttga tccttctttg ttccatgatc ttgaaacggg
    54481 aaaaaaatgg cttgtcaatg aactatggga ttatcgtctg gacacaccga ataaatccag
    54541 cggtatcgta ttacaagaat atgatgcaga gaagaagaag cttgatggtc ccatctataa
    54601 aatatttgca ggtacagaat tagcgaaaac ggaggcacca catttgtatt ttcgtaacgg
    54661 gtattattat ttgatgacgg cagaaggcgg tacaggaaga ggacattcag ttacagtttg
    54721 ccgagcaaag aatattactg gtccttacga gcttgatcct ggttttccta tgctgacagc
    54781 tagtgacaaa cctgcttcta cattgcaatg tacaggacat gggagcttag tacaaacccc
    54841 gtcaggaaga tggtacatga catatctttg taccagacca ttaaacggtg cggctatttt
    54901 gggaagagaa accgctattc aagaagtgta ttggacgtcc gacgattggt taagacttaa
    54961 agatagccag acaactccga tggaagaaat aatgattgag acaaatgaag aggtacaaca
    55021 agaaaaagat catcagttta tggatacatt tgaaggagag ctaaagaaga actggaatgc
    55081 cagacgcatt ttgccaaatg ctgattggtg tgatacaaaa tgtagaccag gttttttacg
    55141 tctgatttcc ggtgaatctc ttcaatctac cttcgaacat catttgttag ctattcggca
    55201 aacggatttt acttttgatg cggagacagc atttgaatac atgcctaata attttaatca
    55261 gatggctgga ctggtactgt acttaaatga atccaattat atttattgtt atgttacttg
    55321 gaatgaggac aagggaaaat gcctacgtat gatagaatca gaaaacggag tagcacaaat
    55381 agaagattgg acgattccac tcacagaaaa gaagactttt ttgaaagtca ctgtaaagaa
    55441 agagacagca cagtttcatt tgaaagacgt atcaactgaa gaatggaaga aagtaggtcc
    55501 gcaaaaaaac atgtgtatac tctcaggagg gtttactgga aattttatcg ggatagcagt
    55561 gcatgatcta aataaaaaaa gaggaagtta tgctgatttt gagtttttca agtatgatgg
    55621 aaaagatcat ctgtaattta attctttaat aaatgaggtt cactaactta ttttcactag
    55681 ttagtgaatt tttttgtttg tatatattgt tatgtaaaaa aagttatcaa tcttatgcat
    55741 caatgttttt agattatttt ttgtttttta tctgtcaaga taatgcaata aaaagccaac
    55801 attgtgaata taaaaacaag aaaaaaagag ttataatttt gaaaacgttt actagaagag
    55861 gtaggaggaa ttcaaatgct ttcacaaaat gctgttacag caaatacaat aaaaaaagaa
    55921 aaaaaggaat ttgggatttc cgataagata ggctacatgt tcggtgatct aggtaactgt
    55981 tttattttag gtttagtcaa tagtttcttg atgatttatt atacgaatgt tcttggcgtt
    56041 tcaggggcaa tcgtaggtac gttattcttg atttcgagaa ttttggatgc gtttgctgat
    56101 gtgatggttg gaagattatg tgatgtctca gagttaacag aaactggccg atttattcct
    56161 tggatcagaa aaatgaagta tccattttgc ttagtgactg tcattttgtt tttgccattc
    56221 gtccaacatc ttccaatgac ggtgaagatt gcttatattt ttgtttcata cattgtttat
    56281 gggatttttc tctcaacaat caatatcccg tatggagcaa tggcagcagc aattagctca
    56341 aatcctaatg accgcacctc gttgtccacg ttccgaagca ttggttctgc gattggcgga
    56401 tcaactacag gattcttcat tccgatttta atgtataccc ataacaagag tggacaacaa
    56461 gtcgtttcag ggaatcattt cttttggatt tcaatcggat gtgctgcaat agcatttgtc
    56521 gcatatatgt taacttgtaa attgactact gaaagagtaa gagttgtcaa aaacgaaaaa
    56581 gtatctgctt ctcagttggt aaaaggtttg ttagctaatc gagcactgat tattttagtc
    56641 attgttgaca ttttcattgt gatcaatcag attttagctg ggacgaatat gacttattta
    56701 ttcaatgatt acttccataa taaacaagca atgtctgttg ctcttttatt tacttacgga
    56761 acagtagtag ttttagcacc atttgctaca aagctgacaa aattatttgg taaaaaggaa
    56821 gcaagcgtat ttgcgttact tgcttcttca tgtatgtact tgctgatgta tttccttcat
    56881 ataacaaatg catgggtata tctgattctt ttatttatcg ctactttagg atctggttta
    56941 ttcaatttga tggtctgggc attcattact gacgtgattg attatcatca atataagaca
    57001 ggcttaagag aagatggaac agtatatgga gtaaattctt ttgcgagaaa agtaggacaa
    57061 gcatgtgcag gagcggtagg cggatttatg ctggcactca ttggttacca atcgtctaca
    57121 acaggtggag ccatccaatc agttttagta caagaaagga tttatacgat ggcaaacttg
    57181 ttaccagcat tctgcttatt tgtatccgca atcattttgc tagtaggtta cccactgaat
    57241 cgttcaaaaa ctgtatttat tggtgaagaa ttgaaaaaaa tcaatgaaag atagggagaa
    57301 acgtattgcg gacaaaaaaa gggattatca atgctttgaa ctttaaaaca aacgacactc
    57361 aacaagatga tacaataata ctgcaaaaag caatcgatca aggtgcgaaa gaacacttac
    57421 ctgtatttat tccaaaaggc atttatttag tcggagccct ttttttaaaa gataagagtc
    57481 atcttatctt tgaagaaggt gcagtcctca aggggagaac agatatcgaa gcatttccag
    57541 aaatcgatac acgagtagcc ggcgtagaaa tgaaatggcc agcagcgatt ttgaatgttc
    57601 tctcggcgaa agatattctt atagaaggaa aaggaataat cgacggtcaa ggagaccatt
    57661 ggtgggagct gtattgggga aaagatcaaa aaagcgggac aagagctgaa tacgatcaaa
    57721 agggacttcg ttggattgcg gattatgcta ttaaacgtcc acgcgcttgt ttactgtatc
    57781 atgcagaaca tgttgttgtt cgtgatttga tttttcagaa atcaggtttt tggaacttgc
    57841 aaatcactta ttctaacgat gtattagtag aaaaagtaat catccgcaac aatgatggac
    57901 caagtacaga tgggattgat attgattctt caacaaatgt gcgtgtctat gaatgtgatt
    57961 tggcctgtgg tgatgattgt attgctatta agtctggcag agatggcaat ggtgcaagag
    58021 tcaatcgaaa atcatcaaga atcgaggttg ctagatgtaa aatccgttca ggatacggtg
    58081 taactattgg tagcgaagtt agtgctggag ttagtgacgt atatattcac gatatcgatt
    58141 tttttcagtc agactgtggt attcgaatga aatcttcaaa agaaagaggg ggagtgatcg
    58201 aaaatatcag ggtagaaaat ctgaatatga ttgatgtaca atttcctttt tcttggataa
    58261 tggactggca taatgaatac aatagaaaaa atagcaatga ccttgctcaa atgccagaaa
    58321 gttggcaagc agtggctgaa gaaatacctg aatcaaagca aatgacgaaa gtcaaagaca
    58381 tacacatcaa aaacgtacag gcatgccttt ctccaggtta ctcacttcct tcccgagctt
    58441 ttgatttagt agcatttcct gaaaagccta tagaagatgt ctgcttttct cattgccaaa
    58501 taactgcaaa agaattcggg cgaatcgaag cagtacaaaa cttatgtttc aaaagctgtg
    58561 atttatctat agaaactggc aacacagctg caaacaatac ttttgacaat cgttgaaatt
    58621 ataataaggt caagcttaaa taatatttta gcttgacctt tatttttttt aatgatatat
    58681 taaacaacgt tgtcgcgctt cattgaaaca ttttatgaaa attccaaaaa agagttgaca
    58741 catgttttta gacgtgataa gataactaag tcgt
//
LOCUS       DAFLWZ010000010        58538 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000010 DAFLWZ010000000
VERSION     DAFLWZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.010"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(68..808)
                     /locus_tag="L1V38_000634"
     CDS             complement(68..808)
                     /locus_tag="L1V38_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315207.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(938..1885)
                     /locus_tag="L1V38_000635"
     CDS             complement(938..1885)
                     /locus_tag="L1V38_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315208.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(2014..2778)
                     /locus_tag="L1V38_000636"
     CDS             complement(2014..2778)
                     /locus_tag="L1V38_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1315209.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            complement(2782..3171)
                     /locus_tag="L1V38_000637"
     CDS             complement(2782..3171)
                     /locus_tag="L1V38_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315210.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3306..3848
                     /locus_tag="L1V38_000638"
     CDS             3306..3848
                     /locus_tag="L1V38_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBN1315211.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3996..4628
                     /locus_tag="L1V38_000639"
     CDS             3996..4628
                     /locus_tag="L1V38_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315212.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(4762..4887)
                     /locus_tag="L1V38_000640"
     CDS             complement(4762..4887)
                     /locus_tag="L1V38_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315213.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5021..5914)
                     /locus_tag="L1V38_000641"
     CDS             complement(5021..5914)
                     /locus_tag="L1V38_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBN1315214.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6096..7022)
                     /locus_tag="L1V38_000642"
     CDS             complement(6096..7022)
                     /locus_tag="L1V38_000642"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBN1315215.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(7107..7868)
                     /gene="pflA"
                     /locus_tag="L1V38_000643"
     CDS             complement(7107..7868)
                     /gene="pflA"
                     /locus_tag="L1V38_000643"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBN1315216.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(8112..10343)
                     /gene="pflB"
                     /locus_tag="L1V38_000644"
     CDS             complement(8112..10343)
                     /gene="pflB"
                     /locus_tag="L1V38_000644"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBN1315217.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(10620..13070)
                     /gene="parC"
                     /locus_tag="L1V38_000645"
     CDS             complement(10620..13070)
                     /gene="parC"
                     /locus_tag="L1V38_000645"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBN1315218.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13082..15127)
                     /gene="parE"
                     /locus_tag="L1V38_000646"
     CDS             complement(13082..15127)
                     /gene="parE"
                     /locus_tag="L1V38_000646"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBN1315219.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(15293..15727)
                     /locus_tag="L1V38_000647"
     CDS             complement(15293..15727)
                     /locus_tag="L1V38_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBN1315220.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            15854..16492
                     /gene="plsY"
                     /locus_tag="L1V38_000648"
     CDS             15854..16492
                     /gene="plsY"
                     /locus_tag="L1V38_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBN1315221.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(16624..17499)
                     /locus_tag="L1V38_000649"
     CDS             complement(16624..17499)
                     /locus_tag="L1V38_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBN1315222.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(17581..18372)
                     /gene="codY"
                     /locus_tag="L1V38_000650"
     CDS             complement(17581..18372)
                     /gene="codY"
                     /locus_tag="L1V38_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBN1315223.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(18390..19790)
                     /gene="hslU"
                     /locus_tag="L1V38_000651"
     CDS             complement(18390..19790)
                     /gene="hslU"
                     /locus_tag="L1V38_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBN1315224.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(19804..20352)
                     /gene="hslV"
                     /locus_tag="L1V38_000652"
     CDS             complement(19804..20352)
                     /gene="hslV"
                     /locus_tag="L1V38_000652"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBN1315225.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(20389..21294)
                     /gene="xerC"
                     /locus_tag="L1V38_000653"
     CDS             complement(20389..21294)
                     /gene="xerC"
                     /locus_tag="L1V38_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBN1315226.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(21492..22868)
                     /gene="trmFO"
                     /locus_tag="L1V38_000654"
     CDS             complement(21492..22868)
                     /gene="trmFO"
                     /locus_tag="L1V38_000654"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBN1315227.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(22837..24915)
                     /gene="topA"
                     /locus_tag="L1V38_000655"
     CDS             complement(22837..24915)
                     /gene="topA"
                     /locus_tag="L1V38_000655"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBN1315228.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(25037..25894)
                     /gene="dprA"
                     /locus_tag="L1V38_000656"
     CDS             complement(25037..25894)
                     /gene="dprA"
                     /locus_tag="L1V38_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBN1315229.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25950..26717)
                     /locus_tag="L1V38_000657"
     CDS             complement(25950..26717)
                     /locus_tag="L1V38_000657"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBN1315230.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(26710..27570)
                     /gene="ylqF"
                     /locus_tag="L1V38_000658"
     CDS             complement(26710..27570)
                     /gene="ylqF"
                     /locus_tag="L1V38_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBN1315231.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            27830..28228
                     /locus_tag="L1V38_000659"
     CDS             27830..28228
                     /locus_tag="L1V38_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1315232.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            28507..29007
                     /locus_tag="L1V38_000660"
     CDS             28507..29007
                     /locus_tag="L1V38_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1315233.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(29090..29641)
                     /gene="lepB"
                     /locus_tag="L1V38_000661"
     CDS             complement(29090..29641)
                     /gene="lepB"
                     /locus_tag="L1V38_000661"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1315234.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(29793..30020)
                     /locus_tag="L1V38_000662"
     CDS             complement(29793..30020)
                     /locus_tag="L1V38_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBN1315235.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(30017..30535)
                     /gene="msrA"
                     /locus_tag="L1V38_000663"
     CDS             complement(30017..30535)
                     /gene="msrA"
                     /locus_tag="L1V38_000663"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1315236.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(30555..31268)
                     /locus_tag="L1V38_000664"
     CDS             complement(30555..31268)
                     /locus_tag="L1V38_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBN1315237.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(31271..32167)
                     /locus_tag="L1V38_000665"
     CDS             complement(31271..32167)
                     /locus_tag="L1V38_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1315238.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(32325..33167)
                     /locus_tag="L1V38_000666"
     CDS             complement(32325..33167)
                     /locus_tag="L1V38_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1315239.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            33299..33952
                     /locus_tag="L1V38_000667"
     CDS             33299..33952
                     /locus_tag="L1V38_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBN1315240.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(34015..34542)
                     /locus_tag="L1V38_000668"
     CDS             complement(34015..34542)
                     /locus_tag="L1V38_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1315241.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(34562..35509)
                     /locus_tag="L1V38_000669"
     CDS             complement(34562..35509)
                     /locus_tag="L1V38_000669"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBN1315242.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(35521..37407)
                     /locus_tag="L1V38_000670"
     CDS             complement(35521..37407)
                     /locus_tag="L1V38_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1315243.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(37567..39645)
                     /locus_tag="L1V38_000671"
     CDS             complement(37567..39645)
                     /locus_tag="L1V38_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBN1315244.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(39658..39933)
                     /locus_tag="L1V38_000672"
     CDS             complement(39658..39933)
                     /locus_tag="L1V38_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315245.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(40295..40750)
                     /locus_tag="L1V38_000673"
     CDS             complement(40295..40750)
                     /locus_tag="L1V38_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315246.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(40904..42112)
                     /locus_tag="L1V38_000674"
     CDS             complement(40904..42112)
                     /locus_tag="L1V38_000674"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBN1315247.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(42224..42556)
                     /locus_tag="L1V38_000675"
     CDS             complement(42224..42556)
                     /locus_tag="L1V38_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1315248.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            42704..43579
                     /locus_tag="L1V38_000676"
     CDS             42704..43579
                     /locus_tag="L1V38_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1315249.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(43661..44242)
                     /locus_tag="L1V38_000677"
     CDS             complement(43661..44242)
                     /locus_tag="L1V38_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBN1315250.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44248..45507)
                     /locus_tag="L1V38_000678"
     CDS             complement(44248..45507)
                     /locus_tag="L1V38_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1315251.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(45509..46555)
                     /locus_tag="L1V38_000679"
     CDS             complement(45509..46555)
                     /locus_tag="L1V38_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315252.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(46790..47065)
                     /locus_tag="L1V38_000680"
     CDS             complement(46790..47065)
                     /locus_tag="L1V38_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBN1315253.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(47308..48618)
                     /gene="der"
                     /locus_tag="L1V38_000681"
     CDS             complement(47308..48618)
                     /gene="der"
                     /locus_tag="L1V38_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBN1315254.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(48800..50029)
                     /gene="rpsA"
                     /locus_tag="L1V38_000682"
     CDS             complement(48800..50029)
                     /gene="rpsA"
                     /locus_tag="L1V38_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBN1315255.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(50164..50844)
                     /locus_tag="L1V38_000683"
     CDS             complement(50164..50844)
                     /locus_tag="L1V38_000683"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBN1315256.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(50893..51528)
                     /locus_tag="L1V38_000684"
     CDS             complement(50893..51528)
                     /locus_tag="L1V38_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1315257.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(51594..52997)
                     /locus_tag="L1V38_000685"
     CDS             complement(51594..52997)
                     /locus_tag="L1V38_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBN1315258.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(52984..54015)
                     /locus_tag="L1V38_000686"
     CDS             complement(52984..54015)
                     /locus_tag="L1V38_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315259.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            54046..54267
                     /locus_tag="L1V38_000687"
     CDS             54046..54267
                     /locus_tag="L1V38_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBN1315260.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(54432..55169)
                     /locus_tag="L1V38_000688"
     CDS             complement(54432..55169)
                     /locus_tag="L1V38_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBN1315261.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(55322..56662)
                     /locus_tag="L1V38_000689"
     CDS             complement(55322..56662)
                     /locus_tag="L1V38_000689"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBN1315262.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(56899..58422)
                     /locus_tag="L1V38_000690"
     CDS             complement(56899..58422)
                     /locus_tag="L1V38_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBN1315263.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
BASE COUNT        16041 a        12335 c         9979 g        20183 t
ORIGIN      
        1 gtataaaata aggaaacgcc gcagcgtttc ctttccaact gtagccgaat ataaatttgt
       61 atatcactta tttaaaatag ctattttctc ccaaagagtt tccttgatca tcgatcaatc
      121 cttgtaatga gcgttctaag ataccatggc tttttttcga ttttttttct tctgactgct
      181 ttgtttcctc taacgttttt gttcgattga atgttcgtac agacggctca ccatttcttt
      241 tttcttgata cggcgtcggt tctgtatcga acaacagata agagtcatcc gtttttttca
      301 tcgattcgat taaatgatcc tcagaaattt tgctttctct agggtctggg ataatcgatg
      361 cgggtacata tttaggaaca aaataagaac gctcccgcac cttcgtgtca acagatgcgt
      421 ttcgtgtagt atgcttggac tctgtccttg tttcactttg tctgacagaa cgagaggaat
      481 caccaaaaag tttttttcgt cctgtcgatg tgatttctga ttggtaatgg ccggtataat
      541 ccggtaattt tcctttatgc ttttccaaat tttccttacg cggagctgac ttcaatccat
      601 ttgttgcacg acgcttgcga cggattttct cggtgttcgt gttcgtgaaa tgaaattctt
      661 tcatctgttc aaacggggac tgattctgtt cagtcaaaag atcttcttgt ccgtcaaata
      721 atactcgctt cttgtcgttg gttaatttta cgcctaactc atcatcgtac gcaggaaaac
      781 ggaaatgttt tcgtctgatt tctttcattc aaaccatcct tctcaaaaat ggaacttttc
      841 tcaataatag cacagattca ttgttttcag tagcaatgcg ctgattattt taagaaaata
      901 gcgatgaatt tcataaatat atatatagta ataagactta attcgttgtc tctctgataa
      961 ctagttcagg aaaaaaacga cgataacctt gactcgcccc tttttcttct atttttttta
     1021 acaacatttc tccacatact tcacccatac gtataatatc ttgcttgatc gttgtcaatt
     1081 taggtgaact gatttggtct aaaaataccc catcaaatcc aatcacacca aattcttcgg
     1141 gcaagtgtcc tccagcattt ataatccctc ttactgctcc tagtgctagc cgatctgaac
     1201 tacatacaaa acaagtttta tctgtaaaat ctgcccagtt ttctgtcata tatctttcta
     1261 cttctgtcga atgatttgga aaccgcaaga ttttactagg aagatcaact tccttcatca
     1321 cagataaata accagtttcc cttgaaattt caaaaggctc gtccacttcg ataccgatat
     1381 aaataatcgt ttgataatct ctttctaagg catattgcgt tgcttttgct gtaccatatt
     1441 cattatcgct gtctacataa tcatatcctt cagaattttc cccaaacaag acaactggtt
     1501 tttccaaacg gtcgatccaa tcgaagtctt tttttctgac acctgtgatg atgtatccat
     1561 cacaagaacc gacgtcgaag gcatcatttg taactaattg gagagaataa tgcgctttac
     1621 cgatccgttt agcgattccc atcagcaaat tcatgtaata gggctcagtt gtgtcgattt
     1681 cttccagtat aaataatttg atgatctgcg accgattcgt gacaagtgct tttgcagcaa
     1741 tatttggacg gtaatccagt tcagccattg ctgagaaaac taactctttc aattcgtcag
     1801 tcacctgttc cggatgattg atgactcgag agaccgtcat ttttgaaaca ttggcacgtt
     1861 ttgcaacatc tgctaaagtg ggcatgctct cttcctttct aacatgttgt cattcttact
     1921 atcaattata ccaaattttc ctaacagagt ttattatagc ccaaaataaa aaacggaaaa
     1981 tcctctatcg tcatgagtga ttttccgttt caattattta tactttttta tcaaattttt
     2041 tgctaaaaaa gtggaagctt cttccattag ttgtatttgt accatatgtc gctgtgtttt
     2101 tgaggaacga aaaacaattt cttttccgta agacttatgc cgattttttt ctacaaatcg
     2161 ttccgtttgt atataaggga ttttttcgtc agcttgtcca tgccaaaaga acagaggacg
     2221 tccagctaac ttttccggct gcaatgacaa atcatagctc ttaacccatg aaatcaaatc
     2281 aaaatagtct tttggtacga cataattata ttccgatgcg cgccttacga tttcttttcc
     2341 atattccaaa ggtgcagggg aacccatcaa acacacgccc gctactatat gaggatgttt
     2401 agccaacaag gcgcatgttg tcattccccc catcgaaacc ccgccaactg caagctgatc
     2461 atgtagaaga cctctttttt ctaaatgctt gataagtgtg tcaaattcaa acagatttcc
     2521 gtagatacta tcccaaaatg tataggatgg aatagaagaa accggctgtt tgcgctcccc
     2581 atgattcatc gcatctggca ggatcacacg aatgccctgc tgcgcaattt ttcttccttg
     2641 cgtcaaaact aactccttac ttgtctgcca tccgtgataa tagatgacaa cgggaatacg
     2701 ttcctctctt aattctttca gaacaacttc taacactgga atatgatgga cagaacgttt
     2761 caatataatt ggattcaatt gttactcacc tattttcatt aaatttcctg atcgccatag
     2821 caaccatgct ccaacagttg tctggaacag gttcagtgta ccaaataata taaatgcagg
     2881 actgaatggc tcgggaaata agcacagaga acaaagtccc accactccta atgctagcga
     2941 aaggagtgga taaatagaaa aattcaaaaa actggcaacg ctaccgaaaa tattaccaat
     3001 aaacagtatc aaaaagaaaa aaacgcttaa aattaaacca tctgtcagcg acatctgaaa
     3061 aacaatgttc tctacctcaa ttggctgttg aatcgaatag acacctaagt atatactgag
     3121 aaggagactt agcacgtggc tggcacaaaa cacacgattg accgttttca ttttaatcac
     3181 ctaacctatc tttataattc tattataatc attttatcat ttttttgtat gtataaagtt
     3241 tcaatttttc ttcacttacg attttttttg atattgttgt tatataaatg aaaggagttt
     3301 tacaaatgat tgatccaaaa atgttgggga tgatcttcct cattaatttt gcttatatca
     3361 ctctgaacac gttacgtttc atgttgacaa tgaaaggcta tcgactgatt gctccacttg
     3421 tcagtatggt cgagatcacg atttatatcg tcggcttatc ccttgtttta gatcgtttag
     3481 ataatccact gaatttattt gtctatgcgt taggttacgc agtaggtatc agtgtcggaa
     3541 ttttgattga agacaaattg gcattaggat acatcatggt cacaacgatt ttgccagcaa
     3601 atagcgcaga agataaaagt ttgccgggta tactgagaga acacggttat ggtgtgacac
     3661 agacttctgc aatggggctg gaaggtgagc ggctagttct cgaaatactt tctcctagaa
     3721 aaagcgaacg tgaactgtat cgcctgatca aagaaatcga agagcgtgct tttatcattt
     3781 cttatgagcc aaaatatatt tcaggtggtt tctggactaa aaaagtgaga aaacgacaag
     3841 gaaaataact cacaaactta aaaactgtct aatatctaaa ttaaatttta aatgttagac
     3901 agtttttatt tattattttg attaaaaaac atcgacatat actcatcaat ttgttattat
     3961 actttatata cttatcaatt taatttggag atattatgga aattcaacgt agaaccacta
     4021 attttttaca tttaggctct ttttttgcaa ctttgacgat cttatttttt ctatgttatt
     4081 cataccttaa gacctcacat gcgccttcta gtgcattagg ctggttgctt ttggatcatt
     4141 ctgatatcac agaagccgaa gaaaatccgt tttttttgat tttgtcttct ctttgcggct
     4201 tactgttttc tgtttatttc ggtgcctatt tttttcatcg acatcctggt acgttaaacg
     4261 aagcttcaag cgtattgatt gcatttaaaa cgttttcttt tttagcaatt cttttttatt
     4321 cgtttaatca caatacgctt ttcttcttta tcatgaatgg tttagtcgtg attttatcca
     4381 tttttactta ttttattttt tcactcattt ttagccaatt gaaatgtccg ctcttctttc
     4441 gattagttcc tgtcacctgt tttatttaca gcttgttttc cttttttgtc cttgctttaa
     4501 tgccactgac caacccttcg acgatccaag tcgcaggaaa tctgttggat atgctcttca
     4561 tcgtcagtct aggtgtattt atgtggcaaa gaaaaaacaa acaaaataaa aagcattttg
     4621 aagcctgact attacgactt cataaatgct tttttagttt taaacacttc aatctaaaag
     4681 aataacccaa gattggataa attattaatg actcgccatt cgtttcttag tgattctgga
     4741 ttatcaaatg gacttcctaa tctaatcagc tagttcttcc cataaaatgc catacttgac
     4801 tgaatcataa tattgattat ttaaaaatct aacttttctt atcactactt cctttgtcat
     4861 tccacatttc tcaccatttt tttgcattcc tttgtttcca gaccatgtag tgaatctaat
     4921 aggtggtaga taggcaaaat actcaaataa ttcttttaac cataaaggaa gagaaaggct
     4981 cctcctgcaa gagtcagtat aatttttgct tactgctctc ttaggtttta ctcactaaaa
     5041 ctgttccata ttctttgata taagaaaatg catgcggtat aaatttcttg ctcagctcag
     5101 aaaagatttg tcgtttaaga aaggccattt cctccattgt caatgaagga tccaatgttg
     5161 gtaattcaat ctcaaaattg tttttttcga caataggtaa ttctaatgtg aatgattctt
     5221 cttcctttat agtattcgtc acaagtagag actgatggaa aatactaggc cggcgatttt
     5281 tatatttatt cttacgtatc ctgtcaacga taacttctat ttgatcaaaa aagtacgatt
     5341 catttacgtc tccaataagt tcggctaatt ctttgaatgc cttcgttaca ggaagctgat
     5401 tcttctgtac aaaaaagtaa ttagccaaag taagcgggaa gtgttctata gaggaaagtg
     5461 tgataaaacg gtacttctca tttcctgcag ttgtcctcag caattctgtc tctcggctgt
     5521 ttcttactcc ataaaaatac gcttctttcc gttcatcttc gaaacaatac gcccaaataa
     5581 cttctcccat cgctaatttt tgttcatcaa cagagagtct cttcaattgt tcagctatgg
     5641 tttcagcagc cgaagtggct tgttgcaagt aatctttagg atcaaatatt ggaaagttca
     5701 aatgatatct tcgttcttcc ctcttgatta atcctgcatc gatcaataaa tcaagaaaat
     5761 gggaaaattt attttgcgaa aattcttttt tcaattctct tagaatcgtt tcttgttctc
     5821 gatgttcata tagataatcg gtcaatgaag aaaaaagcgg atcatcggtc agtttttgat
     5881 aaaagttttc cttatttttt gaataatagt tcatatatgt tctcttttct atccgtttta
     5941 ttttacttaa aaggctttta cgtaaaaagg aggaagaaca agagtcataa ttgactgtta
     6001 ttctcctcca tttcttcggc ctttagtatg ttctatgttt ctttttatat caatcgctta
     6061 tccattcatt ttgaatgctt catactacca tttgattagc taaatacagc cgtcaattga
     6121 ggtacgactt gttttttacg tgaaacgaca cctttaagca aagcacggtt gttggtcaaa
     6181 gttgtttgga aagcttcttc tactttttct tttcctttac cagcaacaag taattctgaa
     6241 tcactgtcta agatgtttgt gacaactaat acgaacagat cgtagccatt tgctttcatt
     6301 tcatcttcca ttgctgcttc tagctctgct tgtcgatcca tcacttcatt aaggtccact
     6361 gtattgactt gagcgatacg aacgttggaa ctgcccattg ggaaactttt tgcatccaaa
     6421 tcaagaagaa ccgcagctga tttatcactt agatttgttc ctgctttcaa catttcaagt
     6481 ccataagtgt ttagatcgac ttcagcgatt gctgcaagtt cttttgcagc tgcttcatct
     6541 tcaggcgtac atgttggtga tttgaacaac aatgtatctg aaatgatagc tgagagcatg
     6601 attcctgcga tttctttagg aattgttact tggttttctt tatatagttt taaaataatc
     6661 gtacttgtac atccaactgg ttctgcacga tagtacaatg gattagctgt ttcaaagttt
     6721 gcaatacgat ggtggtctac tacagctaaa atatttactt cgctgatatc tgaaatactt
     6781 tgttggaatt cattatgatc cacaagcatg acatctgcat tttctgcttt agctgactct
     6841 actactcgtg gtgcagatag ctgaaagtgg tctaatgcgt attgtgtttc ttcattaggt
     6901 gtacctagag caactgcttc tgtttcttta cctaattcat tttgcaagtg tgaaaacgca
     6961 atggctgccc cgattgcatc tgtatctgga ttttggtgac caaaaactaa aatttttgac
     7021 atgtcattcg ctcctttgtg atttctccta tttaataata gcaaaaaaac ggaaagaagc
     7081 aatacttatc ttctttccga tgcgacctat cgcgttaaat attttgtata ctcttctgta
     7141 tgaagcaatc gtttagcatt ttcgacacgt tcttttgtag gtggttcgat cccttctaat
     7201 ggatatttca aaccaagtgt ttcccacttg tattttccca tcgtatgata aggaagaatc
     7261 tctactctgt ctacatttga caaggtttga ataaagttgt ctagtcggat caaatattca
     7321 tcataatcac ttcgctcagg aactagtaca tggcgaatcc aaaccggttt gttgattttt
     7381 gacaaatatt gagccatttc taaaatattt tcattgtccc aatgcgttag ttttttatgc
     7441 tcttcattat cgatgtgttt gatgtcaaat aacagtaaat ctgtatactt catcaattct
     7501 tgaaaacgtg aaaagaaagg ttcttcatac gtaaaaggtt ttccgcatgt atccaatgta
     7561 gtatgcatct tccgctcttt tgctttttta aatagttcga tcaaaaaatc gatctgcaat
     7621 agaggttctc caccactaac agtaatacca cctttatctc cccagtaagg tctgaagcgt
     7681 tctgctttat ctaaaagttc atctgctgtg tattctttcc ctccgccaat attccaagta
     7741 tctggattgt gacaaaattg gcaacgcatg cggcatcctt gcataaacac gacaaagcgc
     7801 agtccaggtc cgtctactga accgaaagtt tcgatagaat gaacatagcc gattgttttt
     7861 tcttccattt aagttcacat cttttctttg atttcatttt aagtacaagt tagctgtcga
     7921 agcgaagctt tctgaacaaa atttttcgca attgccgctt cgttatgtgt aaaatttaca
     7981 gggacggaac atacaagtcc tgcccctgta aatcgtttct ttcaaataag catactgatt
     8041 attcgatttt gatgcgatgg ctattcaacg tcctttcgac gctaagtcga aaaacttttt
     8101 tcacgaactt tttacattct gtcgtgtgaa gttctcatca agacatctaa ttgttgttct
     8161 cttgtcaagt cacggaattt aactgcataa ccagataccc ggatcgtcaa gttcggatat
     8221 ttcattggat tttccattgc atcacgcaat aaatcattac tgaatacatt gacattcaaa
     8281 tgataagctc cttttgagaa gtatccatct aagacattac gcaagttttc gattcttgta
     8341 tcttgttctt ttccaagacc tgaaggattg attgtttggg tatttgaaat tccatccaat
     8401 gcacagccgt aattcatttt agctgttgag ttcaggctag ctaataaccc actttgttcc
     8461 gcattgtaac ttggatttgc tcctggcgca agtggttttc cagcttcacg gccatcagga
     8521 gtatttcctg tatttttacc gtaaacaaca tttgaagtaa tcgtcaataa tgaagttgtt
     8581 ggttttgagt tgcggtaagt tttatgacgt ttgatttgtc ccatgaagta ttccaagatc
     8641 catgaaacta attcatctgc acggtcatca tcatttccgt atttagggaa gtcgccatcc
     8701 acttcaaaat caactgctat tcctttttca ttacggattg cttttacttt tgcatatttg
     8761 atcgctgaca agctgtctgc cgcatgagag atcccagcaa tacctgtagc aaatgtgcgt
     8821 tgcaagtcag aatccatcaa agccagctga gctgcttcat aagaatattt atcatgcata
     8881 taatgaatga tgttcaacgt attgacatat agttctgcta accaatccat catattcatg
     8941 aagttatgtt tcacttcttc aaagtctagt atttctgatg tgattggacg atattctggt
     9001 ccaacttggg cgccagtcac ttcatcgact ccgccattga tggcatataa tagtgtttta
     9061 gccaagttag cacgagcgcc aaagaattgc atgtcttttc cgacaactgt tcctgataca
     9121 cagcaagcaa tcgcacaatc atcagaaccc cattgttcac gaagctgatt atcattttcg
     9181 aattgaatcg aagaactttc gatagcgatt ctgctagcat atgttctgaa tccttctgga
     9241 aggtgttcag aatacaaaac agtcaagttt ggttctggtg aaggtcccat atttgttaat
     9301 gtatgaagca gacggaaatc attctttgta actaatgaac gaccatctaa tcccatacct
     9361 gcaatggata aagtagccca gatagggaat cctgagaata attggttata ttcaggtgta
     9421 cgcgcgaatt tgaccatacg taatttcatt actaagtggt cgatcaattc ttgtgcttct
     9481 ttttctgtga ttactccatt atccaaatca cgttggatat agatatcaag gaatgctgag
     9541 atacgtccga ttgacatcgc agcaccattt tgtgatttga ttgctgctaa atatccgaag
     9601 tatagccatt ggacagcttc ttttgcattt gcagctggtt tagaaatatc atagccatat
     9661 ttcgcagcca tttctttcat ttgcgctaat gcacgatatt gttcagtgat ttcttcacgt
     9721 aaacgaatca cttcttcact cattgtatga taaccagtca tatcatgatc ttttttcttt
     9781 tgttccatca aatagtcgat tccatacaat gccacacgac gatagtcacc gatgatacgt
     9841 ccgcgaccgt aagcgtctgg aagccctgta atgattttgt ttttacgagc agcacgcatt
     9901 tcagcagtat aagcgtcaaa tacaccttga ttatgtgttt tgcgccagtc agtgaaaata
     9961 tgtgtcaatt catcgtttgg tgtatagcca ttgcttttta gcgcattgtt agccatattg
    10021 attccgccga acggcatgaa tgcttgtttc aaaggtttgt ctgtctgtag accgacgatt
    10081 ttttccaaat ctttatccaa atagcctgca tcgtgtgaag taatagttga tacgatttct
    10141 gtgtccatat catagacacc gttacgctcg aattggatat catttaactt ttgcaattca
    10201 tcccataatt tttctgttgc ttctgttggg ccttccaaaa agctgtcatc accgcgatat
    10261 tcagtgtagt tattttgaat aaagtctcta gtgtctacgc cttctttcca tttggtacct
    10321 ttaaatccat tccattgctc cattgtatgg acctcctaaa tttctgtttt atgtaacagt
    10381 ttttacgtga ttagtataac acagcaccct atctttgcaa gggttttctt gttttttatt
    10441 taacaatttt tatgttttat ttacatatat ttaaatcaac gttgacatac caacatttaa
    10501 gcattgtgaa cactttcatc tttttttgca aacgtataag gatttattaa aaatgaatga
    10561 aaaagagacg ccacctgtat taatacagat ggcgtctctt cattaaaata ctacaacagt
    10621 tacgactcga tgaaaatctc aggagcatcg ataacttcga tgacttctcc accttttttc
    10681 tcatccatcg caaatgatcc attcgatgtt cgatcaccta tagggaaatc agttgggtca
    10741 atcgttaact gctgcccttt ttgattcatc aaggttattt cttttgatct tccttccgac
    10801 atatagataa tacggtgcgg attttttttc agctcacgca tgaccgtcac tccccgcttc
    10861 gcacgtgaag tttggctgat ttcttgagca agcatgcgtt taacagctcc tcgctgagta
    10921 acgattacga tcggcgtatc accttctgct aacacaagca gcccgttgat aatcctatct
    10981 ccatctttca aattcataga cttcactcca gctgcctttg ctccaacaac gggaacatct
    11041 gttaaaggat agcgcaaacc cattccttga tgcgttacta agaaaacatc taagcctggc
    11101 tgatcttctt tcagatacac agcaatcagt tcatcttctt ccgcctttag cttcatacag
    11161 ctgagcggac ggctcttata ggtgcgccat ggttcgaact ctgtcattcg tgtttgcttg
    11221 atcaatccat tcttgctgat gaatacaaat gttttctctg cttgaatttt ttgatatggg
    11281 aaaacagcta aaatcgattc gtctacagac agattggaga ttgtttgaga aatgtgctca
    11341 ccagcatctt tccatttcaa atcgggtagt tcatggacag ggcggtagat cacatttgct
    11401 ttatttgtga tcagaagaac atggtccaat gtactcaatt cacctgagta tagcaagtag
    11461 tcgccttctc gcatcccgat ttcttctggt ttggaagcac tataagaacg aaggcttgtt
    11521 cgcttcacat agccttctcg cgtcacactg acaattacgt cttcttgtgc cactaagact
    11581 tgcgtatcaa ttttgatttc ttcgatttcg tcttcgattg tcgttagacg agcggaagaa
    11641 taattttttt tcacttctcg caattctttt ttcataacag agaaaagctc tttgtcattt
    11701 gaaaggattt tattcaactc tgtgatttgc gcaatcaagc tttcggattc cttttgaagc
    11761 tctgtgatat ccgtgttcgt caaacggtat aattgcaatg tgacaattgc ttctgcttgt
    11821 tcttctgtaa attgaaagac gtcgactaaa ttctttttgg cgtctttttt gtctttactt
    11881 tcacgaatcg ttgcgattac ttcatccaga atcgataaag ctttcatcaa tccttctacg
    11941 atatgctgtc ttttttgagc tttggctaaa tcgaattgac tacgttttgt tatgacttgc
    12001 tttcgatgct cgatataact tcttaaaatg tctttcagtc caacttgatg cggagtcata
    12061 tggtcgatag cgaccatatt gaaattgtaa ttgatctgta gctcagtgtt tttgaacaaa
    12121 taattcaaaa ttccttgagc attggcgtct tttttcaatt cgacgacaat ttgcagacct
    12181 gttctatcac tttcatctcg tacttcagct attccatcga ttttcttatt caaacggatc
    12241 tcatccattt ttttcaccaa ggtcgcttta tttacttcat atgggatttc tgtgatcacg
    12301 atttgctgtt tattaccctt cattgcctct atctttgttt tcgaacgaag aataactttt
    12361 cctcgtcctg tttcataagc ttttttgatt tcatcttttc cttgcaagat ccctcctgtt
    12421 ggaaagtcag gtccaggaat atattccatc aatttttcaa ggctcgcttg tggatgatcg
    12481 atcatataga ttgtgccatc gatcacttca gctaagttat gagtcgggat ttctgttgca
    12541 tatccagcag atatacctgt cgatccattg acgagaaggt ttgggtatcg agctggaagg
    12601 actgttggtt ctttttctgt atcatcaaaa ttccacacga gatcgactgt ttctttctcg
    12661 atatctgcta gcatctctcc acttaacttg gataatctgg cttcagtata acgcatcgca
    12721 gcaggtggat caccgtccat actcccgtta ttcccgtgca tttcgatcag tacttcccgc
    12781 aacttccagt cttggctcat gcggaccatc gcttcataaa tactgatgtc accatgagga
    12841 tgataattcc ccatgatatt tccgacagat tttgctgatt tacggaatcc tttgtcatac
    12901 gtattgccat ctttgttcat ggcaaataat atccggcgtt gcactggctt caatccatca
    12961 cggatatcag gcagtgcacg ttcttggata atatatttgg aataacgtcc gaagcggtca
    13021 cccatcactt cttctaaagt taattcttgt acttcttgtc gattttccat caggtgacct
    13081 cctattctac ttcaaataac tgattgtttt catttttatc tgctcgttct tcatctaata
    13141 aatcattaga aactgaagga gagatttcag tatcctcttt tttatctaag atactgccat
    13201 cttcttcgag cgtaaattgc acgtgatttt cgatccattt tcttcgaggt tctactttgt
    13261 cacccatcag tgtggttact cgacgttcag cttgcgcagc atcatcgata cggacgcgga
    13321 tcaacgtacg ggaagtcgga tccatcgttg tttcccacaa ttgttccgca ttcatctctc
    13381 caagtccttt atatcgctgc agcatatatc ctttgccgac ttttttaatc attgctgcca
    13441 attcgtcatc tgtccacgca tattcaatga cttgcttctt tccttgtcct ttggatactt
    13501 tatataaagg cggtaacgcg atatatactt tcccagcttc aatcagcggt ttcatataac
    13561 gataaaagaa agtaagcagt aatacttgaa tatgggcgcc gtctgtatcc gcatcggtca
    13621 tgatgattac tttgtcgtaa ttacagtctt cgatagaaaa ctcaggaccg actcctgcac
    13681 caatcgtata gatcatcgta ttgatttctt catttttcaa gatatcttgc attttagctt
    13741 tttcggtatt gatgactttt cctcgtaaag gtagaattgc ttggaacttt ctgtctcttc
    13801 cttgtttagc agatccgcca gcagaatccc cttcgactaa atacaattca tttttcttag
    13861 ggtttcggga ttgtgcgggt gtcaattttc ctgaaagaag agattcgcct tttttacgct
    13921 tcttcccatt tcggctttct tctctggctt tacgtgctgc ttctctcgct tctctggctt
    13981 tgattgcttt acggaccaac atctggctca tttcgctatt ttcctgcaaa taaaagccca
    14041 tttgttcact gatgacgtta tctactacgg tacgagcaac tggcgtacca agtttttctt
    14101 ttgtttgccc ttcaaattgc agaagatttt caggtacacg gatagaaagt acagcagcta
    14161 acccttctct gaaatcacta ccttccagat tcttgtcccg ttctttcagc aaaccaactt
    14221 ttctcgcata ttcattataa gatttcgtca tcgccgcttt cataccagct tcatgggttc
    14281 ccccatcttt tgtccgaacg ttattgacaa aagataaaac attttctgaa taaccgtcat
    14341 tgtattgata agcgacctct acttcgatac cttctttttc tcctgaaaaa taaacaactg
    14401 gtgtcaatgt atctttttct tcattcagat aatcaacaaa ttctttgatt ccttcttcgt
    14461 aatgaaaaat ttccttgact ggttcttctc cacgaagatc agaaagagag attttaacgc
    14521 cttttagaag aaaggcagat tctcttaacc gttcggctaa aatttcatat gaaaatttcg
    14581 ttgtactgaa tattgtatca tctggtaaaa aatggacagt cgtcccgttt gctttttttg
    14641 tttttcctat ctttttcaaa gtaccgtcag gtttaccgcc gtttttaaat ttctgctgat
    14701 actctacgcc atctctaacg atcgttacaa ttagccattt cgataaggca tttaccacac
    14761 tggctcctac accgtgcagt ccaccagaag ttttgtaccc tccttgacca aactttccgc
    14821 cagcatgcag cacagtaaaa atcacttcaa ctgttggtat tccggaagca tgcattccta
    14881 caggcatccc acgtccgcta tctgcaacag ttatactatt gtcttcatgg atggtcacat
    14941 caatctcact gccataacct gataatgctt cgtcaactgc attatcgacg atttcataga
    15001 ctaaatgatg caagcctcgg ctgtcagtgg atccaatgta catccctggt ctttttctaa
    15061 ctgcctctaa tccttccaat acttggatgg acgagtcatt gtattcgttg tttacttttt
    15121 ttgccaaggc aaacgctcct tcaataatac tttgcggcaa aaccgcacca cgattatcat
    15181 actagaaaag gtcgtgaaaa aaaagagggt agacgagaaa tcaattttaa ttatctccta
    15241 accgcttttt cgacattccc ctctatcgat catctcttct ttgtggtcat ttttattttt
    15301 ggttttcttt caacttacca agttcaatct taatacaacg atccattacg atatctgtac
    15361 gtcctgcttt tcttagcatc tcagctgctt ctttgttttc aatccctaat tgtgcccaga
    15421 acactttagc atcagttttc aaaaaatcac ctgctatttc aggtaaaaat tcactccgtc
    15481 taaatacatc tacgatatcg attggatcat cgatttctgt caaattcgca tagactttct
    15541 cgcctagaat ttcttcacca gccaataatg gatttactgg tatgatttta tatccattgt
    15601 cttgcaatac ctgtgcaacc atgtaacttg ttcgttctgg tttattgctc aagcctacga
    15661 cggcaatatt ttttgcttct tccaaatagt tgaaaatcgt ttcttgtgtt ggatttttta
    15721 cagacatttc tgccacccct tgcttttctt tttattccat ctattatact tgtatctttc
    15781 attttttcaa ttgttcctgt tacctattca tgctaaaata aaggatagtt ttcaacttga
    15841 aagagggtaa aaaatgaaat tgatcttatt acttatttta gcatatcttt taggttctat
    15901 tccttccggt gtctggattg gcaaattgtt tttcaaaaaa gatatccgac aacacgggag
    15961 cggtaatact ggaacgacca atacatttcg tgtattaggc aaaacagccg ggattgttgt
    16021 cctgcttatg gatattttaa aaggtacatt ggctacttgt ttgccgatga tcttccacct
    16081 ttctgggatt aaccctcttt ggtttggggt atgcgccatt cttggccata catttccgat
    16141 ttttgctggg ttcaaaggag gaaaagctgt tgcgacaagt gcaggaatgc ttttaggatt
    16201 taatcctgta ttttttgttt attcttgtat catctttatc gttagtttat tttgtacaag
    16261 tatggtgagt ttgagcagta tgatcagtgc agtattgatc actttatcta cgatcgtcct
    16321 tccttatgta gctcctgtga ttttggctaa gcccaattgg ttactgacga tcattgcctt
    16381 tttagtttct tcctttatct tttatcggca taaagacaat atcaagcgta tcagaaacca
    16441 tactgaaagt cgaatcccgt ttggtttgaa tagcagcaag aaaaaatcct gatacttttt
    16501 cattccaaag agataaaacg ggagtgtgac aaatcgatgt cacactccct tattacttac
    16561 aggatagctt ttttacacac cttggtaaac ggtgttccct gctaacttct cggtcacaac
    16621 ctcttacttc actgtgatgg aatattttgt cttgaagatt tcatgggcac ctagttgatt
    16681 gatccctact ttttccatca agtttccact actgttcacc gtgtcagcga ttccgcacca
    16741 cggttcgata caaacgaaag gcgcttcttt tggataagga gaccagatcc ctacataagg
    16801 catatcttta tagcttaaag ttacgctatg ggaagatttt tcacttcgaa tggcgtacgc
    16861 atttagaccc cttgtttcaa aaaccaaggc atcttgctca aaaagttcac gattcaaagc
    16921 cagattcgta tttgtctgac ctaacgtctt ttgatccata tcgatgaatg ggcctttcaa
    16981 tggtaggcgt aatcttgatt tcaatggaga aaatgccaga tagaaatctt caaatgacaa
    17041 tccttcttca agaggtacat tgaaagcagg atgtccaccg atagaaaaga acatttcttt
    17101 ttcaccggta tttgccactt gataatgaac cgtgatgccg tctcctccta attcatagct
    17161 gatcactaat tcaaaatcaa atggatactt ttctaatgtc tccggcgtac tccttaagat
    17221 gaaactagcc atttcttgtc catgttcaat gacttcaaaa tccatatccc gagcaaatcc
    17281 gtgttgcccc atttgatatg ttttcccttg ataaacatac tgatcatctt ttaaacgtcc
    17341 aacaaaaggg aataaaaccg gtgcatgtct gccccaatac gctggatcac cttgccagat
    17401 atactctaaa ccatgttctt ttgatttcag actgatcaat tccgcaccgt gttcagcgat
    17461 ttcggcgatc agctggtcat tttgaataat aacagtcatt gccattcctc caacttcgac
    17521 ttacttttta aaatgggaag gctggaacaa acatttctat ctgccccagt ccccttactt
    17581 ctaataactg tgttttgcta actcgtcttt aaaacgggaa ttcaatactt ttaaataagt
    17641 tcccttcatg cctaacgaac gagattcaat gattccagct gattccaatt ttcgtaaagc
    17701 attgacgatc acagaacgag tgatgccgat actatcggca atattagaag cagtcagacg
    17761 accttcatct ccatccaatg cttcaaagat agcttgtaca gccttcaatt cgctataaga
    17821 taatgtgttg attgccattt ggacagccgt tgcactccgt acatctgctt cgatgcttcg
    17881 agacttctga taaaggatct gcataccgac aaccgtagct ccatattctg ctaagactag
    17941 atcgtcatct gcaaacgatt gttccatacg agataagata atcgtaccca aacgttcgcc
    18001 agctccaaag atcggaacga cagtcgtcag accaaatgga tatttctctc ttgactctac
    18061 cggaaatgca gtaatatcac tagtaattgg gatattagct tcagttttca tcaactgtgc
    18121 cactgtatca gtataagatt caggaaattg tttctcaaca aacattgttt tgattcgttc
    18181 attgttcaca tcgtgacgtt cattataacc tagtaatact ccgtcacttc ctatgatata
    18241 ggtgttgctg tcaagaatac cacctagtgt gacagccatt ttatcgtaag gcaaatctgc
    18301 ttgcatgtca aaagtattct tttgctgcaa aagtgtgttt atcttgcggg ttttcgttag
    18361 caagtctgtc attgtcgtcc tccgattttt tataaaatat agcgacttaa atcttcattt
    18421 gccgcaattg agccaagttt gtcatccaca tatgcttctg tgatcgttat ttctcccatt
    18481 tgcatatctg gtgcttcaaa taatagatct tctagtagtt tttccaaaat ggtatgcagt
    18541 ctgcgtgcgc cgatattatc tgtgtcacgg ttgacatcga aagcgatttg agcgatccgt
    18601 tcaattgctt cttttgtaaa cgtaactgac acattttctg taccgatcaa cgcgacgtat
    18661 tgttttacta aagcattatt tggttcggtc agaatcttca caaaatcttc agctgtcaaa
    18721 tcatctaatt ctacccgtat cgggaagcgt ccttgaagtt ctggaattag atcacttggt
    18781 ttagacaaat ggaaagctcc tgaagcaatg aataggacgt gatctgtttg gatgatcccg
    18841 tattttgtgt ttacttgtga accttcgaca attggcaata tgtctctttg gacgccttct
    18901 ctggatactt ctccagattg ctgtgattta gaagtgatct tatcgatttc atcgataaaa
    18961 ataattccac tttcttccgc taatttgatt gcctcactat ggatatcagc atccttgact
    19021 aattttgctg attcttcctt gatcaataac tctaaagctt ctttgactgt taccgtccgt
    19081 tccacttttt tcttcggtgt caaagcacct agagtttcat ttaggtcgat ccccatttgc
    19141 tccaatccat tgttcatcat tggtgcaggt ttcttttggt cttcaacttc aatggttact
    19201 tcacgactat ccagtaaacc cttttgtagt tgttccaaga ctgtacggcg attgattcga
    19261 atatcttctg tcacttcttc ttgcggttca gcggtatttt gctgactagc attaaaaaga
    19321 ttcatcattt gttcaaattg attagtggat tgtttctgtt cttttttgat accaggtacc
    19381 aagattttta ccaaacgttt ttctgcattt tttttagcac ttgtgtatac acggctgtac
    19441 tgctcttttt ctacgatttg gatcgcattt tctactaaat cccgaaccat tgattctaca
    19501 tctcttccga cataaccgac ttcagtaaat tttgttgctt cgactttgac aaatggtgca
    19561 ttgacgattt ttgccaaacg tcgtgcgatt tctgttttac cgacccctgt aggtccgatc
    19621 atcagcatat tttttggtgt aatatcttgt tgcatttttt catctaactg caaacggcga
    19681 tagcggttac gcaaagcaac ggcaacagat ttttttgctg cgtgctgtcc tacgatatat
    19741 tcatctaatt cacttacgat ttgtcttggt gtttgtttta attcatacat atctactcac
    19801 ctcttacagt tcttctacga taatattatg attagtaaag atacagatat ctgcggcaat
    19861 atttaacgca ttttctgcaa tttctttcgc actcatgtcg ttttgagcat agtttttcat
    19921 tgctcgggct gcagccaacg caaaattccc tcctgatccg atagctaaga taccatcatc
    19981 tggtgtgata acttctcctg tacctgaaac aagaagcatt tctttatcat tcattacgat
    20041 cagcatcgct tcaagttttt gcatagattg ctgtgtccgc cattcttgag ctaattcgac
    20101 agctgcgcgt tgtagattcc cgttatattc gtttagtttg ccttcaaatt tttcttctaa
    20161 agtaaacgca tctgcaacac ttccggcgaa acctacaaca acttctccat tgtagatacg
    20221 tcgtactttc tttgcagtgc ctttcatgac aacagattca cccattgtta cttggccatc
    20281 tccagccata gcaaatttcc cgtctttttc gacggcacag atagtggttg aatgaaatgg
    20341 tgattcgacc atgtttgttt cctcctaaat ttgttctttt ccttattttt acgctcttgg
    20401 atggaaagaa cgatagtttt tttgtaaact ttcttttgtt acatgggcat agatctgggt
    20461 agtcgataaa ttggcatgtc ctagcaattc ttggactgtc cgcaaatctg ccccattatt
    20521 taataaatga gtagcaaatg tatggcgcag catgtgagga tggatatcac tatccaaact
    20581 gctttttttg atcatttgat tcaagacata ttcaattcca gtaggcgtga ttggttttcc
    20641 atgatgattc acaaaaacga tatcatgctc ttcgtgatat tttgtcatca atacctggcg
    20701 gccttccctg aaatattctt gcagagcatc ttgagcaaaa gaacctagag gagcatatct
    20761 ctctttgttc cctttaccat ggatcaacat gacctctgaa tcaaaatcaa tgtctgatac
    20821 cgacaaactg ctacactcac ttaaacggat gcctgacccg taaaggactt ccagtaaagc
    20881 gcggttcctc aaatccaaag gactatctcc tgctacgctg tcaaaaagtg cttgcatttc
    20941 attttcataa aaaaaacgtg gcagtctcaa atttttcttt ttgagatgaa cgtaagaaaa
    21001 tggattttct tttatcactt cttctttgag aagatactga taaaacgaac gtaggctggc
    21061 tatcttgcga ctgatagaat ttctgctata gctaggacga tgatcagcta atgcactcaa
    21121 atagacacga accgtaaaat attccgcctt cagcagatca gcgtctccag attcctccaa
    21181 aaaatgtttg aaatggagaa tgtcttcttc atatgcttct ttcgtttttt ctgaatatcc
    21241 tctttcgaca atcaaataac gcaaaaattt ttgttcccac gtggcttctg tcattttctc
    21301 accttccttt tgtcccagag aataatttag cacagcgttt ataaaaagac aaataaattg
    21361 tcagaattta accaatattt ctaagtttgt tcacaattgg cgcaattcct cacattttgt
    21421 ttgagaaatt cttaagaaaa acgcaagaaa aagagcgaga ctatccgtct caccctcttc
    21481 atggagtttc cttactcatt tgggattgca gttttttcta attctgtttt tattgcctca
    21541 ttagctttta aagctcgttg tgcaattgct tcatatcttg cttttttgtc tcgaatgcgc
    21601 tctggcagtt caggaaacag accatagttg gcattcatcg gttggaaatg ttttccttcc
    21661 gcatgagtaa tgtagtaagc catacttcca atagctgttt cttgtggaaa ctcgactggt
    21721 tccatttctt ttgctaagcg tgcggcgttg attccagcaa gtagtccgct cgctgcactt
    21781 tcaacatagc cttctacacc agtcatctga cctgcaaaga acagatcttc gcgtttcgtt
    21841 gattggtaag tcggtttcag caattctggc gaattcataa agctgtttcg gtgcatcaca
    21901 ccatagcgaa cgaattcagc attttctaac ccaggaatca tccggaaaac acgtttttgc
    21961 tcgccccatt tcaagtgagt ctgaaagccc acgatgttgt ataaagaagc tgcagcattg
    22021 tcttgacgca gctggataac agcataagga cgtttgccag ttttaggatc ttccaatcca
    22081 actggtttca taggtccgaa aagcatcgtt ttgaatcctc gctgtgccat tacttcaatt
    22141 ggcatacatc cttcaaaata tttttctttc tcaaaagatt taagttctgc cacttcggca
    22201 ttgattagtg cctcatggaa agctttgaat tcctcttctg tcatcggaca gttcaagtaa
    22261 gctgcttctc ctttgtcata gcgggacttc aaatatactt tatccatatc gatcgtagct
    22321 ttgtctacga ttggtgcagc tgcatcatag aaataaaaac catctgaacc attgaatgct
    22381 ttgatgcttt ctgctaatgg atgagaagtc aaaggtcctg ttgctactac ggtgattcct
    22441 tccggtattt cagtaatttc ttcgtttatc actgttacta atggatgctc tttgactttt
    22501 cgggtaattg tttcagaaaa agaatcgcgg tcaacagcta aggcaccacc agctggcact
    22561 gctgtttcat ctgccgaagt gattactacc gaattcaatc ggcgcatttc ttctttcaat
    22621 aaccctactg cattagccaa actgtttcct cttaatgaat tggaacatac tagttcagca
    22681 aaattacttg tgtgatgcgc ctcagtcgat ttgactggac gcatttcata taaacggaca
    22741 gggactcctg cttgtgcgat ctgccaagca gcttcacttc cggcaagccc tgctccaaca
    22801 acatttacca ttttcaatga aagaacctct tttctattat ttttggatgt cttcttcgta
    22861 atctccattt acacagacta cttgtttacc gcctttgact ttcttctcga ccagatatcc
    22921 gtcacatttt ggacaatttc tgcccactgg tttatcccaa gaagtgaatt cacattctgg
    22981 gaaacgggaa caaccataga atagtctgtt tttcttagat tttcgttcaa tgacttgtcc
    23041 ttcatgacat actgggcaag tcacaccgat ttcttttacg attggtttcg tattccgaca
    23101 atcaggaaaa ttactgcaag cataaaactt cccatatttc cctaatttta tcaccatcgg
    23161 atgtccacag acatcacaat cgaatcctgc tggttcatct ttgatttgaa ttttttcgat
    23221 tttttcttcc gcattcgtca gttctttttc aaacggttta tagaaacgat caaccacttt
    23281 gacccacgct tccgtgcctt cttcaatttt atccaaatct ccttccattt ctgctgtgaa
    23341 atggatatcg acgatttgag ggaagaattc acagattaat gaattgacaa tttctcctag
    23401 ttcagtcggc tcaaatcttt tttgtgtcaa ttttacatag tagcgtcttt ggatcgtatc
    23461 aagtgttggt gcataagtgg aaggtcgccc taccccgttt tcttctagtg cacgaatcaa
    23521 cgtagcctca ctaaaacgtg ctggtggttg agtaaaatgt tgttttggtt caatatcaac
    23581 agattggact acatcgcctt cttcaagttc tggaagaata ttttctttct cttctttgcc
    23641 gtcatctcta ccttccacat acacttgcat gaatcctttg aatttgattt ttgaaccgtt
    23701 cgcaatgaag atgacaccat tttgttctaa tgtcactttc attgtatcta aaatagctgg
    23761 tgtcatctga ctagccacaa aacgtgacca gatcaatgta taaagtttca attgatcttt
    23821 atctaaatat tgtttgagtt catctggtgt acgaagcaca ctcgttggac gcacagcttc
    23881 atgggcatct tgtgcgcctt gagcattttt gatctttcgg tgatcatgtc tagaaaattc
    23941 ttttccatac gtatcttcaa taaatgctgc ggcctctgct tttgctgtat cggcaatccg
    24001 ggtagaatca gtacgcatgt atgtaatcaa gccgactgtt ccttgtttac ccaaagtgat
    24061 tccttcatat aattgctgtg ctaccatcat ggtttttctt gttcgaaagt ttaacttacg
    24121 ggcagcttct tgttgcaggc tacttgtagt gaaaggattc gcagggtttc ttttgcgctc
    24181 tttcttttct acttttttaa cttcgaagtc tgttccatca attctagcag tgacttcttt
    24241 tacactttgt gcatctggta atttcttttt cttaccgtcg attccccaga aatttgcttt
    24301 gaatttcttg cgagcttttt taaaattacc gtcgatgctc caatattctt ctggaacaaa
    24361 ttctcggatc tctttttcac ggtcaataat aatttttaaa gcgacagatt ggacacgtcc
    24421 tgcacttaac cctttcttga ccttacgcca gagaatagga ctgatcgaat aaccaacgat
    24481 tctgtctaag gtacgacgag cttgctgtgc atctactaaa tctacatcga tcgttcttgg
    24541 ttccttaaaa gctgctttga ctgcgtcttt tgtgatttca ttgaagacca cccgattttt
    24601 ttctttcaga tccaacccaa gtaggtacgc taaatgccaa gcaatcgctt ctccttctct
    24661 atccgggtca cttgccaagt aaactttttg agcttttttt gctgcggctt tcaggctttt
    24721 gatgacatcg ccttttccgc gtatagaaat ataatggggt tcataattgt tttcaaaatc
    24781 gatacccatt ttacttttcg gtaaatctct tatatggcca acactggcca ttactttata
    24841 gtttcgtcca agatatttct caattgtctt ggcttttgca ggtgattcta caatcactaa
    24901 atatttatac gccattactg aatggactcc tttccattgt cgtgttccta ctattaaaag
    24961 aggattcata caaatcgtag ctaatcatat ccattcagaa aacgtttgtc aagaaaagca
    25021 aatgaaaagt atggtgttat tctttaaatt ctgccaagat atcttcaccc gaaaccgtgc
    25081 aaactgcacc gtcttggatc aaatgatgac atccggtaga atgttctgtt aaaatatttc
    25141 ctggaacaga aaaaactgtt cttccaagat ccaatgcttg ctgtgctgtt atcagagagc
    25201 cgcttttttt cttggcttca aagacacatg ttcctttaga caaagctgcg ataatccgat
    25261 ttctcattgg aaaacaatgc tttttcgggc cggattgagg aggatattca ctcaaaagaa
    25321 gatgatcatt tgcaatcacc tcttgcaagt cacgattttc agcaggatag acttgctcta
    25381 tccctgttcc aatgactgcg attgtccgtc caccatgaga gattgctgct tggtgaccgt
    25441 atgtatctat ccctttcgcg cagccactga cgatcacata tccagcttct atcactggtt
    25501 ttagtaaata ataaactgtt tttttggcta aagcagaagt gtgtcttcca ccaacaacgc
    25561 ttaacatgtt acaagaaagt aaagatagat caccattata aaacagtaca attggcggat
    25621 aggtcaagtg aagcagctga gggggatatt tgggatcaaa gcaagtgata aacgactgtt
    25681 tcgattggat tttgccccag ttagcgtgaa tttcctgcca acttttgcga aacagctccc
    25741 ggtgtttggt tattttacct atcttaatga tgtcttcaaa tccgatttct ttataaggat
    25801 actgcatcat ccagttagca agtgcccatt ttccttgact actgattcct tttgtataag
    25861 caagtttcaa taaattttct tctatttgat acatcataaa accgcctttc gtctctcttt
    25921 ctaataagat acgtaaaagc ggctgttttt tattgtaaat atttttttac aggtgcaaaa
    25981 cttttacgat ggattggcgt aattccttgt cgttcaagtc cttctaagtg ttcctttgtt
    26041 ccataacctg cattatgcga gaaaccatat ccaggataaa gcacgtcata ttctttcatc
    26101 aattggtctc gatatacttt agcaatgata cttgcagcag caatcgacac agatcgtgca
    26161 tcccctttga ttattttttc ctgctgaata ggcaaatcca aggtcatcgc atcgatcaac
    26221 aaatagcttg gtacaatgga caatttttct actgcttgga tcatcgctaa tttacttgct
    26281 tcataaatat tcacatcatc gattgtctgc tgatcaacga tcccgatccc gattgccagg
    26341 gctttttctt gaacttgttg ataaagaagt tctcgctttt tctctgataa ttgtttggag
    26401 tcattcagcc ctaatatgat ctcatttttc ggcaagataa ctgcagctgc cacgacaggt
    26461 ccagctaatg gtcctcttcc tacttcatca atgccggcaa tccattggtg accttgtgcg
    26521 tacccttgct tttcaaagca aaacatttct tcatattttt ccttaattaa tgcttccttt
    26581 ttcaatcgtc gttcaaaaga agccagtgct tgctgcacgc ctttgcgtgg atcatttctt
    26641 aatgattcta gtgtaggatc atctattctc tgtatgcttt tcaatcgttc tttgatactt
    26701 tggatggatt cagtcatcac ttttttgctc catttcttcg caacgatcca gtgtgtatcg
    26761 tccaagtttt ccttgacgaa tatcatgcac gactaattcg ctgccacgat catagtcttc
    26821 tttataccca cgttttgctg taatatccat cagtaattcc ggtgccaatt tttcttcttg
    26881 ctcgattgat aaaccataac gatcgctgat tcttcctgaa taatatcggg caaaaaagtc
    26941 taatccgtaa atcgctaaat catctaaatg gacaagctgg tctttgatcg cgcctgtcag
    27001 cgctagtttt ttgccgattt cttcatcttc aaatttgggc cataaaatcc ctggtgtgtc
    27061 taacaattcc aactcattac ctaaacgaag ccactgctga ccttttgtta cgccaggctt
    27121 atttcctgtc tgtgcaattt tcttgcctac tagtcgattc atcaacgtag atttcccaac
    27181 atttggaata cctaagacca ttgcccgaat agcgcgaggc ttgatccccc gagcagcatc
    27241 tcttgcccgt ttttctttca atgcttcttt agccgcaggt actagacctt taattccttt
    27301 actttcttgt gccgtgatag ctaatgcaag atggccttgt ttacgaaaat attcttgcca
    27361 cagctttgtc tgttgtggat ctgccagatc cgctttattc aataaaacaa ggcgaggttt
    27421 ttgctgaatg atctgatcta gcattggatt acgagaagat aaaggtaatc gtgcgtctac
    27481 caattcaaat acgatgtcca catatttcat tttttcagaa acttctcgtc gggcttttgc
    27541 catatgtccc ggaaaccatt ggatggtcat tgttctctcc attcctttca taccggaata
    27601 ttccccggct ttacttgttt ttttcttttt caatataaat tcactttttt attataaaga
    27661 aattccatct attagttaag tgaaagtgaa ccagtcctca ttctatcaca tcttcacttt
    27721 tttgatgatg caaattttta ttttggtttc tatatatgaa tctaaatttt tgacagcgtt
    27781 tcctaaataa gagatgatag acgaacaaaa cagaaaggag acgaaacaaa tgaatagtat
    27841 ggtttttgtt aattttcctg ttgctgatgt caatcgttcc gttgcttttt atgaaaagct
    27901 gggttttaaa aaaaatgaag aattttctac tgaagaagct ggttcaatgg tatgggatga
    27961 cactttttgg ataatgcttc tctctcatga tttttataaa aaatttataa aagataaaga
    28021 aatagctgat aataaaaaaa caagtggtgc tttgatttcg tttagtgttg aaaatgcgga
    28081 tgaagtaaaa aaatttgctc aaattgcaaa agaaaatggt ggtactttcc acgaagtaga
    28141 tatgggaatg cctgaagaag aaatgttttc attagaagtc caagatctag acggaaatac
    28201 attagaaccc gtatggatga agatgtaagc agataactaa tctgacgttt tttataacaa
    28261 aaaaacaaag gcggatgata cgataagtat tctccgcctc tatttttttt attcgtacaa
    28321 tctctttttt acagtttata aaagcagtct tctcaccctt tttttaattg ttagatgcca
    28381 gtgtatgtaa atcaccaatg tgtcatgaca cattggtgat tttatggtat ccttttatta
    28441 ttaactgaca aaggagagaa tattttgaac actttgattg caaaagacgt ttttagattg
    28501 cccgaaatga atgcaagatt gttgtcgacc tctgctcttt tattagccct tgatgtcatc
    28561 ttatacaaga tagcgattgg tcctgcttat tttcaaatca cattcggatt tttaagtatg
    28621 gcgcttatgg gttatctata tggaccgatc tgggctggtt tgcttgaaat gttgtcgaac
    28681 actttaaatt tcacgatatt tggttcagga acgtttcaag ctgcttttct tatcacggct
    28741 ttccttggtg gatttattaa tggcttattt ttatatcata aaaagataaa cctgccttcc
    28801 gtcatcgctg cccaattatt gattatgatc ccagtcagcc tttttatcaa ttcttggctg
    28861 atgtctgttt tgtttggtgc agatttcaaa gtaatttttc taggtagatt catcaggaat
    28921 atgatccaaa tccctattca aataatggtt gtttattcat ttatcaaaac tttagaggct
    28981 agaaaagtgt ttaaacgagc tgtttgattt tacgtactaa ggtagtaaac tgattttgga
    29041 ttaaacaata aagcgtgcag tctcaacaga ctgcacgctt tattgtttct cactggatcc
    29101 attttatttc atcaagtgga taatagacaa atcttgcttt acctagaata tcagttttat
    29161 tgatcgtgcc aaacgaacga ctatcttttg aaactcttcg attatctcca agtacaaaat
    29221 aattatcttc cggaagcttg gattgtcccg ttagctcttg tagtgtaaag tccgtcgtat
    29281 aggatgcatt tgcatgatct gatttcaggt ttttagttag ataaggttcc ttaactactt
    29341 tcccattgat cttcaattga tcattttggt agctgacatt ttctcctgga agaccgatta
    29401 ctcgtttgat ataaatcgtg ccatctgcta attgaaaaac aacaatatca aatcgtctga
    29461 tctccgaaaa tttttccatc acaaccatat caccttgctt caacacgttt tccattgaat
    29521 tgccttccac tggtaccggg atgaataaaa atccccgcaa catgaacgca aggaatacag
    29581 aaacaagtaa gtatttgaat acaagccaga agcgattaat atagcgttgt ttttttgtca
    29641 atctctatca atccatccct ctttttttca ttctttcttt attataagaa aaatatcaaa
    29701 aaaatgcgac tagatagctg aaataaaaat aattctttca attaggctat tggacaaaaa
    29761 acttttttga tcataaagta caaaactatc tcttatatgt catgattatt ttctaaatat
    29821 ttttcccatg cttcgtcaaa gatatccatg gacggcaaat agtcgacatt cagttccaga
    29881 taattagaaa tttcttcgta gctagagctg tgcttaggaa attggatgtc tttaccggct
    29941 tctgtagcga aaacagataa agcatcatgt gtgccaccgc ctcgcagtgt cattaaataa
    30001 tgaaaaaagc ttcgattcac ccttcgttcc tccaattttc ttcgataaag gcagcccggc
    30061 gtgcatggtt tcttttaaaa ttttcaggat gctttttata atactcttga tggtcttctt
    30121 ctgctagata aaatggttgg gctggttcga tttttgtaac gattggctgt tcgaaacgtc
    30181 cactttcagc taactgtttc ttactttttt cagcaatgat ccgctgttct tctgtcaaat
    30241 aaaagatcac cgggcgataa ttgtcaccgc gatcctcgaa ttgtccgaaa gcgtcagttg
    30301 gatcagtttg ctgccagtaa agttctacta attgttcata tgaaatcaat gttggatcat
    30361 agataatctc cactgcttct gtatgtccag tcgtttggct ttttacttgt tcataagtcg
    30421 gatctggtac atgccctcca gtatatcctg acatcactgt atggatacca ggaagcgtgt
    30481 cgaaaggctg gatcatacac cagaagcagc ctcctgcaaa tattgctcgt tccattatga
    30541 ttccccctct aatactactc atccgatgat tttttatttt cttttgtctt gctttcagta
    30601 ctgctggtgc tagttttgtt ggtatttgag ttgtttgaag catcagaggt atcttttggc
    30661 aaatatagac taaaccgaat gtcatcattt actaagtcga ttttatctgc tttaatatac
    30721 atcccgtttt gcattcggaa ttgatccaac ctaagcatga tagtcagatc atctgtattg
    30781 acttcgatcc aatctggtaa tttatagttt ctcttgatca tattcatcac atctttgatt
    30841 ggcaaactca atgttccgat agaaagactt ctagctttta gttggacatt tccgttttcc
    30901 atcacatacg gatcaaaata taaatagaaa tcgataggaa aacctagtac ttcgaaagta
    30961 ccattgagta gtgcttcatt ttccaaataa aatttatatt caatatcact atctttttga
    31021 tactcactaa ggaaaaagct gatgatttga ttgacttttt ctttatttga attgatcgtt
    31081 aagacaggat ctccttgtct ttccgtaaga gctggtattt ctgggagttc tggttcccga
    31141 ttagcaaaaa tacggctgcc taaaaatacg gtcgaaccaa gtactacccc aagaaggata
    31201 aggaaggcga atttccagta atttgttttc tttgttttgt ttgaagatac gtcagatctt
    31261 gttttcatgt ttattgatca tcctccttct ctaaccattg gttttgtgtc tcgatcagct
    31321 gatctctcac tgcatttgcc atcaattgat aacctaaatt atttggatgg aaatgatctt
    31381 cttcatagag cacattattt ttgatgccat ttagattttc tgtcgtgcta gttgtttgat
    31441 ctgttccttc ttctgtgaca cctacttcct gattcaatcc ttgataaagc aaatcattga
    31501 ttgggataaa gtagcagttc ggcatttttt ttgtcaccgt ttctgttcct ttgttccaat
    31561 tgttaacaat tgtctgcatg tcagtgatct caggaaagtt caaataaaat ggattgtaga
    31621 tgcctaaaat gtaaataggt gcggttttat tgagggatcg aaattcttcc aatagttctg
    31681 tgacattttc ctgatagttt ttcagtggct ttttaaagga attgaccgtt aacccgaata
    31741 aattattttg gataactttc atcaaatcat taccgccaac agtcagtgtg ataaaatcag
    31801 ctgttttgat attgtttcga atttcttctt ttgtttttac tcgctttaag atctggtcac
    31861 ttcgttcacc atttacacca tagttttctg tttcaaccgc ggtcaaatta taacggtctt
    31921 ttagatcatt tgcgacaagg ggaacgaatc ctccttgctt ggtttgatct cctactcctt
    31981 cagtcagcga atctccgata gctatgtagt gaagtttttc ttttttattt ggatcttctc
    32041 tcacagtagt tactggtttc attagtgggc cagctttcgg tatagaagca gctaaacctg
    32101 catagatgat gatcgcaatt aataatggga acaaaacgag gatcaaatgt cgtttcgtta
    32161 atttcatttt ttcacctctt gtattcgatt ggttctaatg ttatcaaaaa ttttatcaaa
    32221 aaggtagtct ttatgaaaaa agaaaacaat tattttccta attttataaa gaaaaagaga
    32281 ataagctgca agcctttcag gctgagggct tatcctcttt tcgactaatc tacataatac
    32341 atgattgcaa acgcgtcttt accagtatgc gtagcgataa ccggattcgt atgcagtaca
    32401 gggatatgca tgtccgggaa taattcttgc aaaccctctt tgaattcttg cgccaattct
    32461 tttgcatccg catgtgaaat accgatttgt cgcacatttg gcaattcttt cagttcattt
    32521 ttcaaattat taaaccattt atcgaacgtt ttctttcctc gccccttagt tacagggatt
    32581 aattcagaat gggcgaaatt catcaccacg cgtatgttca aaacactaga cagcaaacca
    32641 gttgttcggc tgattcttcc accttttacc aagttatcta gtgtggatat tccgatgtat
    32701 aattttgtat tgtcttgtac ttttttgact tcttcaagga ttttctctac tgttttacct
    32761 tcttttgcta attcagctgc tcgaattacc tgaaaagata atccttggtc agtggtatca
    32821 ctgtcgataa ccgttacttt cgtttttgtt agattactgg cttgtcttgc tgcttctact
    32881 gttccactca agccttttgt catatggatc gaaatcactt cactgccgtc ttctcctagc
    32941 tcatcataca tcgagatgaa ttctccaatt ggtggttggc ttgttttggg cagatttttt
    33001 gctttcgcca tcatttccat aaatctttcg ccgtctagtt ggtcatcatc gggatatact
    33061 gttccgtcga tcatgatgga tagcggcatg acacgaatgc ctaaagcatc gcgtacattt
    33121 ttttccatcg tacatgaaga atctgttacg atttttacat ttgtcattat tttctctctc
    33181 tctttcttta acaagatgcc ttattcatgt taaactacat gtaagacaat ttctattttt
    33241 agtataacag acaaataatg atttttcatt aattacacct agtaaaggag ccgttttcat
    33301 ggaaaaaacg aaatttaatc gaacgtatga aatattaaat gaagtgttta atgcagtcac
    33361 ccatggaatt gggactggat tgagtatcgc gggactagtg gttcttttag taaaaggtgc
    33421 ccacttgcat tcctccctcc atattgtctc ttatgctatc tatggatcga tgatgattct
    33481 tttattttta acgtctactt tgtttcattc attgattttt acaaaagcaa aaaaggtgtt
    33541 ccaagtattc gatcatagtt cgatttttct tttgattgca ggaagttata ctcctttttg
    33601 tttgctgagt atccgaggat ggctaggttg gactttattt gtattaatct ggttgtttgc
    33661 gattcttggc attatatata aagcgttgac gttgcataaa cgggagagag tatcaaaagt
    33721 atctacgatc atctatattt ttatggggtg gctctgtgtc gtggctgctg ttcctcttta
    33781 tcactctctt ggaatgactg gtgttatttt gatggtagca ggcgggcttt cttacacgat
    33841 aggcgcattc ttttatagct tgaattctat ccgctatatg catgttgttt ggcatttgtt
    33901 tgttatgtta ggtgcaggtt ttatgtactt ctctgtttta ttctttactt aataaaaaaa
    33961 ataaagctat ggatgggaca gctctaaata acagctagtc tatccatagc ttttttatat
    34021 cgtcaattcg cctgtcccgc tttttacagg attctcatta cgctgatacg tttcaaattg
    34081 atgcggataa cgattttttt catccatttc tccttgacta gtattgatca gtgaccaatc
    34141 agaccagtca acaggtggaa aataagcatc tccatcgaat acatgatgga tgactgtacg
    34201 gtataatatc gtacaaaatg gcagaaattc ttgataaaca gctgaccctc cagcgatgaa
    34261 aaagataccg tctgtttctt tttccagagc aagcacgtct tccacactat gcatgacatg
    34321 cacgccttct gctttatagg aagaatctct cgtcaaaaca atcgtctgac gattcggcaa
    34381 cggacggcta cccatccctt cgaatgtttt tcgtcccatc actagtgtat ttgcttctgt
    34441 catttgtttg aagaatttca gatcatttgg caaacgccaa ggaagacggt cttcttttcc
    34501 aatcaatccg ttttcatcct gtgcccaaat tgcagctaac attttctcat cctttctgat
    34561 tctaaacagc gataggagct ttgatcgccg gatgtgggtc atatccttct aattggatat
    34621 cttccatctc aaaatcaaat actgactgct tttcctgatt caaaactaaa gtcggaaatg
    34681 cgcgtatttc tcggctcaat tgttctttca tttgttcgat atgattgata taaagatgag
    34741 catctcctaa tgtgtgaaca aattcgccaa ccgctaaacc tgtttcatgt gcaattaggt
    34801 gagtcagcaa cgcataactt gcaatgttga acggaacgcc tagaaacaca tccccactgc
    34861 gttgatacaa ttggcagctt agccgtccct cttgaacata aaattgaaac atcgtatgac
    34921 aaggaggcaa agccatgcta ggaacatctt ccggattcca tgcagaaacg atcaatcttc
    34981 tagaatcagg agtctttttg attgcttcga tcacttgttt gatttgatcg ataaagccac
    35041 cgtcttttgt ttcccagtga cgccattgat agccgtagat gtgtccaaga tcgccgtatg
    35101 tttcagcaaa ggaatcatcg gttaggatct tctcgcaaaa aagcttgctc tgctttttat
    35161 attcttcatt gaattcagga tctgtcaaac atctatggcc aaaatcagtc atatctggtc
    35221 cattatagtc tggacttttg atgtagcgtt caaatgccca ttcatcccaa atatggtttt
    35281 tattttgtaa tagatagcgg atattcgtat ctccttttaa aaaccaaagc aattcgcttt
    35341 tgatcaatcc aaaaggtact cgtttcgttg ttaacaaagg aaaccctttt tgcagatcaa
    35401 accgcatttg gtatccgaat aagcttaatg tgcctgtgcc tgttctgtct tctttacgat
    35461 gcccttcttc caacaatttt cttcctaagt caagatacgc ttgttccatc ctttttcctc
    35521 ctaatcttct acccattcac tcaagtattc ccaccgtgcc attttttctt caagttgtgc
    35581 ttctgtttca gatacgtcgt tttgcaattc ttgtaatcga gtgaaattat ctccttgatg
    35641 attcatctct tcttggagca atgagatttt ttcttcaagt tctgcaatct catcttcaat
    35701 cgtttcccat tctttttgtt ccatgtaaga taatttcttc ttttcagcag gttccttgct
    35761 ctgtattttt ggtttcgctt tttcagcagg ctgctgggtc tctttttgct tcagtaaata
    35821 actggacatg tttccgtaat aaagttcttg ttttccgttt ccttggaata ctaataactt
    35881 atctgctacc ttgtccaaga aataacggtc atgggaaaca gtgatcacag cacctggaaa
    35941 acttctaaaa taatcttcca aaatcgtcaa tgttgctatg tccaaatcat tggtcggttc
    36001 atccaataat aaaacattag gttgctgaat cagcagtttc aacaaaaata accggcgttt
    36061 ttctccgcct gaaagtttgc ctatcagtgt cccatgcata aatcttggaa ataaaaatcg
    36121 ttcaagtaat tctgctactc cgatttgact gccatctgct gtttttgctt cttcagcagc
    36181 ttcttgtaag taagcaatca tccgtttatc tggtgccatt tcttcatttt cttgtgtata
    36241 atacgcaaga tgaaccgttt caccgataga cattgtaccg ctatccaggg gaattctgcc
    36301 agctagaata ttaagcaatg tcgattttcc cgcaccattt ttaccagtaa tacctagtct
    36361 ttcccgagat tgaatcaata aatctaaatg ttctagcagt gtttggtcat ttatacggta
    36421 actgccatct ttgatttcca gtactttttt ccctaaacgt tgtgtcgcta ggttcagctc
    36481 taaatcatct tcttggttta cttggtacaa gttctccttt agatcttcga aacggttgat
    36541 ccgtgcttgc tgcttggtgc cacgtgcctg tacgccagcc ctcatccaag ctaattcctg
    36601 tttataaagc cgcttgcgct tttcttcttg ttctacttct acacgatcac gttctgcttt
    36661 ttctaagacg taagcttcat aatttccttt atactcgtat aattttccaa atgaaagttc
    36721 gaagattcgg tttgctactc tatctagaaa ataacgatcg tgggtaacca tcaatagtgc
    36781 gccacggtat tgtttcaaat agttttccaa ccactcgatc gcttcataat ctaaatggtt
    36841 tgttggttcg tctagtaata gtaaatcggg ttcatcaatc aacacttgcg ccagactaac
    36901 tcgttttttc tgaccacctg ataaagtact gattttttta tctaattcac tgattcctaa
    36961 tttttgcaaa ataatctttg cgttggtatc tgtagtccaa gcatcttctt tattcatttg
    37021 ttcttctgct ttagcataac gtttttgcac atcagggtct tctccgtttt cccctagttc
    37081 gatcaatgct tcctcatatg ctcgaacagt ttggatcaag gggctgtttc cttgaaagac
    37141 tgcttggaga acagttaatt catcggaaaa ttcagctgct tgagaaagat aaccaatacg
    37201 gtaatcagtt ggataaaaca ctgtttgccg atcaccgtcg ctgctatcga taccggcaat
    37261 aatatttaag agacttgttt tacccgtccc gttcgtccca atcaacccga tacggtcttt
    37321 ttcgtggacc aaaaaagaaa tctggtcaaa caaatctttt tcaccataag tttttttgag
    37381 gtcagttact tttaattctt tcaacatgtt ccctccttat cttggatatt gtatcataaa
    37441 aatagtgaac ttcaggaaaa tttttttggt atttgttctt tttgtgttct caaaaaaaga
    37501 acaggaccga ttcgatcctg ttctgatatg ttttgttttt tataaaactt gaaaattttt
    37561 acctttttat tttattggac tcgttttttt tgactttgct cgaaacgcaa atcggaaaga
    37621 aaagttatca gatggtttgt tcatcgtata agattctaac aaattgatat tcctgcgata
    37681 gctgttcgca gaaaacgtcg tgattttttc agcaacttcg tattcatcaa tgatttttct
    37741 ttcaagataa taacctctta gcattttttt cgtaaacaga ctatcttgct ggatcatcca
    37801 cgaagaaatc aaattccccg agttcatttt tattccttca agtttgcgtt gctggataaa
    37861 aaattgaacc atcgtttcat cataaatatc agtcaagtta tctaaacttt caataatcaa
    37921 ctgagtattt ttttgatatg tctctctgat ttcttggata tcttcatcac taataaatgt
    37981 ctgacgatca gcatatcttc tttgccaaaa cattttcgga tggagaacga ttcgcattaa
    38041 cctacggaca acaatgaacc aaaagccgat aaaagacaaa atctggcttg tgatagaatg
    38101 ttcgaatcga gaaagaaaac gggagtaaaa acgataacca ttagaagaaa gcttgcccga
    38161 acgataactt tcatccaatc catcccgttc gatcgacaaa atcagtgctt gtatttcttg
    38221 tacttcttgc ttttcatcat cggttaaatc ttccaagtac agatcacgta tccgttcttg
    38281 ataattttct atcactgctt cagtggctaa aaattctttt gtattacgat caatttcctt
    38341 tatttctttt cgcaaaactt caacgacctc ttctaaaatc atcaaagcat tcaaatccgt
    38401 gcttttcgct tcctctgttt ccgtcagcat aggcaagaca atgatcccta tgaccaaagt
    38461 cactaagatg acacccgccg tcagaaacaa aagcaaagac cgctggtaaa acatcatatt
    38521 attgattgaa aatggcaaaa taaaaatcgt agccaaactg actgttccct ttacaccgcc
    38581 aaatgttaag atcaagatct cgttcaactg ttttttgaac tttttactgc catctttgaa
    38641 tacataaaaa agactgatag aaatgaatct gatcacaaaa agcatgacag agattaatac
    38701 gataatcgct aataaaagac cgtttggata taaaccgtct ccccatactg gcgagaacac
    38761 ttgcgtcaat tcgattccta aaaatataaa tactaatgca ttcagtgtaa aagcaatagt
    38821 tgtccatgta ctgtgggaca agctcgacaa ttctgcatca aacacagaga ttttcctaaa
    38881 accagaagct tggagaatac ctgctgccac tgcagcaatg attccagata catcaaatgc
    38941 ctctgccaat acataggcta gaaaaggaag caaaagttcg atcagcagat accctgtgac
    39001 atcttgtgct gatgcttttt cgatcaaatg aattattttt tgtttgaacc agacaagcaa
    39061 aaagccgatc aaagctcccc caatactaga aactactaga ctcatccccg cgtttactgc
    39121 tgaaaaagat ccggtgatca gcgcaccaag agcaaactgg aaggcagtaa caccagatgc
    39181 atcattcaaa agaccttctc cttccaaaat atgcatcgcc tttttaggga tattcactcg
    39241 tccagaaaga gaactgactg ctaccgcatc tgtcggacct aacgctgctc caaaagcaaa
    39301 gcaggcagca agtgggacac ttggcaacag gaatgataac gtcgcaccta ccccgacaag
    39361 ggtcaaaatg actcctccaa atgccaagaa caaaattgtc ccgaaatttt tgagaatcga
    39421 agaaatatct gctttttctc cttctctaaa taacaatggt gcaataatca taactaagaa
    39481 caattcaggt tcaaaatcga ttgattgtcc ccactctgtc agacctaata ccactccaag
    39541 gaaaatttgg atcagtggag ctggaatcat tggcaaaatg cggctagcta tgttcgataa
    39601 ggtgatcgtt actgcaaata caataactaa ctcagcaaat tccatcgtcc atccccttta
    39661 ttttttattt tgtgtaagca tttttaaaaa ttgttctttt ttctttaaaa ttttggtttc
    39721 gactacttca acctgtgttt ggttcccctc taattcacac tgtacacgtt ttgactccaa
    39781 acgaagcaga tcatgtttca gacgttccaa ctgacgatac atcaatatat ttcttttacg
    39841 caacttacaa agtatttgac ggcggtcatc catcgaaagg gcgccatagc gatcatgcaa
    39901 cagttttttt tgttgttcaa aactctctct cattttccag atctcctata cacaaacttc
    39961 catcattata gcaaagttct ttttggatga aaaatatttc attgtttcat cgtttattgc
    40021 tagttagaaa tttccataaa tttttcaacg cctcattcta ttccaaatag tatcagatat
    40081 caagtaaaac ttaagaaaga taaaagtttc tgacaaaagg atgtttactt tcccattcct
    40141 gcctttcttg ttcttttatc acaacaaaaa aatggggctg cgacaaaaat cttgtcacag
    40201 tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat aagacacatc
    40261 tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc ccgtatacat
    40321 cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt tcgctgattt
    40381 ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat gggaagtaca
    40441 caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct tcgtatttca
    40501 atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt gtcgcaactg
    40561 cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt tcaacaaatt
    40621 cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga tcgccgatat
    40681 gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc gctgtcattt
    40741 ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac ctcagtttag
    40801 cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt atctgcccac
    40861 tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc aatttttctt
    40921 tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct acgacggctt
    40981 tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca gtttcttcta
    41041 gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa cgatcatagg
    41101 attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat tcttctactt
    41161 gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct ccagtttctc
    41221 gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta gaacacttcc
    41281 acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg atcaataatg
    41341 cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa cgtaaaagtg
    41401 cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca ataaatgcat
    41461 ggattcccgc ggcccgttca tttcccaaga gcatcttgat gaattccaca tttatacgtt
    41521 ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag gtttcttcct
    41581 ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt aaggcatctt
    41641 catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct agatcttgca
    41701 gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca ttgatcgtaa
    41761 aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga tctggtctac
    41821 ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt tcatcatttt
    41881 ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga aaaagctgtt
    41941 tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc tggttcagca
    42001 agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc tctaattttt
    42061 tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc atttttccaa
    42121 cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga ctgtttgaca
    42181 agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg tccttacgct
    42241 caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa acttcagtta
    42301 agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca ccaagttctt
    42361 ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa gtgtggttga
    42421 cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct aatggagaga
    42481 aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata ctgtataaag
    42541 aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt aacgcaaatc
    42601 ctagataaga gcaattgaga aaatcgaatt tccatgctac atttaggaag gaatttctaa
    42661 atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca aacgaaaaac
    42721 agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg gtcttgttta
    42781 cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct tgatcttaag
    42841 agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc cattgatttt
    42901 actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag gtacactttc
    42961 tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt tacagcatga
    43021 tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg ggatcgtcta
    43081 ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag aacaaaatta
    43141 cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac ttgcttcatt
    43201 aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg ttttcagtcg
    43261 tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg tcgtctccaa
    43321 caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg tgactttcct
    43381 ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg tcgttagctc
    43441 tagtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag ctttcctttc
    43501 aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc cacagacaag
    43561 attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag attccacatc
    43621 cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta tgttcactta
    43681 cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca tcagataatt
    43741 tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca taaagcattt
    43801 ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca gtatcttctt
    43861 cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat agatattctc
    43921 ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc caattcaaac
    43981 ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa aacaatttca
    44041 tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca aaattcgccc
    44101 cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa ttcaagatcc
    44161 aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa aaattcttct
    44221 tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta ataatgacag
    44281 tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt gcgctctttt
    44341 cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg gttcatgtga
    44401 tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt ctaattcatt
    44461 ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca tctgattgat
    44521 cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta aagtaagtaa
    44581 tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt ctgctcgctg
    44641 tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga cttggtaagg
    44701 attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt cttcttcttg
    44761 aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt ctcgaagttc
    44821 ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa aagctagctg
    44881 gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta cgatagctgc
    44941 ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg agattcctga
    45001 aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct ctttgaaacg
    45061 atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat caggaagcaa
    45121 cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa cttggtacaa
    45181 atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca ctttttccag
    45241 gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta acgggatgtt
    45301 cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt ttgcttcgat
    45361 caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg ctgggtcttc
    45421 ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg ataaagcttg
    45481 caacattttt tcgctatttg tattcatttc aattccctct tatctcactg acgatttgtt
    45541 gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat ccgtctatta
    45601 tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa agaacttttt
    45661 ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca agcaagtcca
    45721 gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga ttccacacga
    45781 aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg ccattttcgg
    45841 tcagataaaa agcttgttca aacagtttac cataatttga caggttttct gcctctaatt
    45901 gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt aattgctttt
    45961 tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc attccgcaac
    46021 agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg attgtttgat
    46081 cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt ggtagctgca
    46141 aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca gggatcatcc
    46201 atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc atgatccctt
    46261 catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg acgaaatcaa
    46321 gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata taccagtcat
    46381 tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca taatagcgct
    46441 gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga ctgactagcg
    46501 tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt tccatacgca
    46561 tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa agataagagc
    46621 aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg tgttttctat
    46681 gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc taggaaataa
    46741 aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct tatttaacag
    46801 cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga atttcgattt
    46861 cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact tcaaagttac
    46921 caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata gttgaaaata
    46981 cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa gcaacttttt
    47041 cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga gatatgatag
    47101 aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa atattgatta
    47161 acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg tttttaccaa
    47221 ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt tttcttttga
    47281 aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa ttcggatgga
    47341 cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt cataagaaaa
    47401 atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga cagcgacttg
    47461 tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat tgattgctac
    47521 agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct ggttcatact
    47581 tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg cagaaacaaa
    47641 aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt cgaaatcacg
    47701 cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa taattccacg
    47761 accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc cttcttcagc
    47821 attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac gcatcacgct
    47881 gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg tatctatcat
    47941 taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc gggtcgttcc
    48001 ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca aagaggattt
    48061 accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct cttcttcagt
    48121 ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta gtccatggct
    48181 tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga tatcgtttct
    48241 catttctgga ttatctactt tattgactgc taaaatcact ggtttattac ttctgtataa
    48301 aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga ctacacaaat
    48361 gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat ccataaaagg
    48421 ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac ctaaccattc
    48481 accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa tcgagatacg
    48541 ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc caacgattgc
    48601 aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac ttagtttaac
    48661 gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt ttattcctta
    48721 ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc tttcatctca
    48781 gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct tctacttctt
    48841 ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct tctggtaatt
    48901 cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct aaagctttga
    48961 tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact ttcacttcgt
    49021 caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt tgagagatat
    49081 ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt gtcaaacgtt
    49141 taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct gaccaaggtc
    49201 caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg atagacaaca
    49261 ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct acatgactat
    49321 gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca aatgcgccaa
    49381 aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata gttgaaagaa
    49441 tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat aagatcaaac
    49501 gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct ttatagtctg
    49561 aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca cgtacaccga
    49621 cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg accttgccct
    49681 cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg cgttttgaaa
    49741 gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact aaatctaata
    49801 catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat aattcttttg
    49861 ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt ttgtcttcaa
    49921 tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg cttttcattg
    49981 cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata acacttgtcc
    50041 tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga ttattcaaaa
    50101 aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat tttttttctt
    50161 aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg caacgacttc
    50221 tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct tcagcggaga
    50281 gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca gtgtttcaag
    50341 atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac gctcacttac
    50401 gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc cgatgtctct
    50461 tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa ctaattcttc
    50521 tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg gttgacggat
    50581 ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt gttgcgaaaa
    50641 agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa aagatacatt
    50701 gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg tataaatata
    50761 attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag caggcccgtc
    50821 gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa aagccgcaaa
    50881 gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa agttgtttgg
    50941 atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct cagccacttg
    51001 ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg atgaagaagg
    51061 tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct cacttgagga
    51121 agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat cttgagacac
    51181 agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg actcctcttt
    51241 tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag ttgctgctgt
    51301 tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa tagcgataca
    51361 taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct tttgttgtct
    51421 ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt cccatggttc
    51481 ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg ttttacctcc
    51541 taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa aaatcaatgt
    51601 tccatgtttt ttttaaataa atttagtaaa atcgttcccc aatgaagttg ttcagtctta
    51661 gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc acaacaattc
    51721 tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct gcggcagttt
    51781 tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt ttcctgacgt
    51841 ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc catccatttt
    51901 ttttgcagct catcaaaggg agcttgctct gtggcatatt ccaaataaag ctcaaaactt
    51961 tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc cccactttga
    52021 taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat ttcttgtaca
    52081 tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc agatttatcg
    52141 atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt tacaaactgc
    52201 tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc aactgtaaaa
    52261 cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca ataaatgatt
    52321 gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg ctgcgttttc
    52381 cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt tggtggtcga
    52441 tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc cgttagtgcc
    52501 agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata ttctggacgg
    52561 aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa cgcaatattt
    52621 tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact caaaaacaaa
    52681 aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga aagtaaacta
    52741 ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg atcttccatt
    52801 agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc cgtcaattga
    52861 tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc tccatcaagc
    52921 aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa atattttttt
    52981 aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt gatacaaacg
    53041 aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc actctcgcac
    53101 ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc actcgtatgg
    53161 aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc ctctttttaa
    53221 atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct gcttggtgat
    53281 catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt gccaaagcga
    53341 atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt gttgcagata
    53401 aaccgctgac tcatcattgt tttttgccag ctgataagga agcagccctg ttcgctcatt
    53461 tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg aaaacagctg
    53521 caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc tttcactaag
    53581 ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat agtcttgaat
    53641 acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc aactagtttc
    53701 ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat gttcggacaa
    53761 catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga tccaaccttg
    53821 ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg gaaaactgtt
    53881 atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg ttcgttttcc
    53941 cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa atagcgataa
    54001 aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc actactatgt
    54061 aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc gccagatatt
    54121 ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc tcatcaacag
    54181 ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg tccagttcga
    54241 gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg tacactaagt
    54301 tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat cccgacttat
    54361 tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg accctatagg
    54421 acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac gatcacagtt
    54481 tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc atagctgcca
    54541 aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg taaatactgc
    54601 ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt gatcgataaa
    54661 acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc catgaagaat
    54721 acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc cattacgcca
    54781 cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt gaccttatcc
    54841 gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc gactgaaaag
    54901 ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac gagagcacca
    54961 ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc aaaaaataag
    55021 taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga tggttcgtac
    55081 gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat gatgactaag
    55141 ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct gagtgacccc
    55201 tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc aaactttcca
    55261 gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg tatgtttatt
    55321 tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct ttatacatac
    55381 tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca gggaacatcg
    55441 caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct gatacaaacg
    55501 gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc actaactcac
    55561 tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc aacccatatt
    55621 tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta acagggattc
    55681 tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca aagttcatcg
    55741 ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca gttgcatttt
    55801 cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct gaaagagcaa
    55861 ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg atacttttac
    55921 caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt ttcaatgctt
    55981 cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca acattcaacg
    56041 ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa gcttgcaata
    56101 agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct tgcgtaattc
    56161 cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca tctgtaccaa
    56221 agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct ttgacggcat
    56281 acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact aaccagccgt
    56341 cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct gctggaacaa
    56401 cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct gaataaccgt
    56461 aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt tccaatactt
    56521 tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa tctgcttcat
    56581 ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt tcatgatgtt
    56641 gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag ggtcatgtca
    56701 aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg ctccatcagc
    56761 aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg agctattgac
    56821 ttatccacgt gcttatcgat agccgtttat cggtttcttc attcttatga tagaccttgt
    56881 acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac agatggctac
    56941 aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat cgaaacgagc
    57001 aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta ctaaaccaga
    57061 tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt cacccatagg
    57121 tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca agaatgacat
    57181 agggatatag aaaataaatg taataatgat gaatacactt gaagataatg aacttaatcc
    57241 ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa ccacttggat
    57301 accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac cagctaaaaa
    57361 ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga tggacattac
    57421 taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca tgcttttacc
    57481 tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt caaaaatcgt
    57541 gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac caaaagtaat
    57601 aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac gaccgattgc
    57661 ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg attttgttgg
    57721 atctttttcg atctttgatg cataacgata cacatataca atagaaatag ctaacaaaat
    57781 aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa cagcttgtga
    57841 agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt gagaccctac
    57901 taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga ctgggatcag
    57961 taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc ctaatgcaaa
    58021 taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct tcacaactga
    58081 agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc caccaacaac
    58141 caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct cccccgctgg
    58201 tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt gaggattttg
    58261 ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac tatagtgccc
    58321 agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata agaccgtata
    58381 cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct tcctttcttt
    58441 tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt atcagaacaa
    58501 aaataataac acgcattttg taaaactttt gttcaaaa
//
LOCUS       DAFLWZ010000011        58313 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000011 DAFLWZ010000000
VERSION     DAFLWZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.011"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..832)
                     /locus_tag="L1V38_000691"
     CDS             complement(<1..832)
                     /locus_tag="L1V38_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1315264.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     Y"
     gene            complement(1056..2996)
                     /gene="thrS"
                     /locus_tag="L1V38_000692"
     CDS             complement(1056..2996)
                     /gene="thrS"
                     /locus_tag="L1V38_000692"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBN1315265.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3333..3512)
                     /locus_tag="L1V38_000693"
     CDS             complement(3333..3512)
                     /locus_tag="L1V38_000693"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBN1315266.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3559..5382)
                     /gene="cadA"
                     /locus_tag="L1V38_000694"
     CDS             complement(3559..5382)
                     /gene="cadA"
                     /locus_tag="L1V38_000694"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1315267.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5660..7939
                     /locus_tag="L1V38_000695"
     CDS             5660..7939
                     /locus_tag="L1V38_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1315268.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8032..8679)
                     /locus_tag="L1V38_000696"
     CDS             complement(8032..8679)
                     /locus_tag="L1V38_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315269.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8858..9577)
                     /locus_tag="L1V38_000697"
     CDS             complement(8858..9577)
                     /locus_tag="L1V38_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315270.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9708..10859)
                     /locus_tag="L1V38_000698"
     CDS             complement(9708..10859)
                     /locus_tag="L1V38_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBN1315271.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11076..11816)
                     /locus_tag="L1V38_000699"
     CDS             complement(11076..11816)
                     /locus_tag="L1V38_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1315272.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11820..12143)
                     /gene="rsfS"
                     /locus_tag="L1V38_000700"
     CDS             complement(11820..12143)
                     /gene="rsfS"
                     /locus_tag="L1V38_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBN1315273.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12200..12793)
                     /gene="yqeK"
                     /locus_tag="L1V38_000701"
     CDS             complement(12200..12793)
                     /gene="yqeK"
                     /locus_tag="L1V38_000701"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBN1315274.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12777..13427)
                     /locus_tag="L1V38_000702"
     CDS             complement(12777..13427)
                     /locus_tag="L1V38_000702"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBN1315275.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13437..13748)
                     /gene="yhbY"
                     /locus_tag="L1V38_000703"
     CDS             complement(13437..13748)
                     /gene="yhbY"
                     /locus_tag="L1V38_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBN1315276.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13764..14873)
                     /gene="yqeH"
                     /locus_tag="L1V38_000704"
     CDS             complement(13764..14873)
                     /gene="yqeH"
                     /locus_tag="L1V38_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBN1315277.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14870..15397)
                     /locus_tag="L1V38_000705"
     CDS             complement(14870..15397)
                     /locus_tag="L1V38_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBN1315278.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15577..16362)
                     /locus_tag="L1V38_000706"
     CDS             complement(15577..16362)
                     /locus_tag="L1V38_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBN1315279.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16355..17224)
                     /locus_tag="L1V38_000707"
     CDS             complement(16355..17224)
                     /locus_tag="L1V38_000707"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBN1315280.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17225..18604)
                     /locus_tag="L1V38_000708"
     CDS             complement(17225..18604)
                     /locus_tag="L1V38_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBN1315281.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18612..19031)
                     /gene="fabZ"
                     /locus_tag="L1V38_000709"
     CDS             complement(18612..19031)
                     /gene="fabZ"
                     /locus_tag="L1V38_000709"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1315282.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19056..19532)
                     /gene="accB"
                     /locus_tag="L1V38_000710"
     CDS             complement(19056..19532)
                     /gene="accB"
                     /locus_tag="L1V38_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBN1315283.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19535..20770)
                     /gene="fabF"
                     /locus_tag="L1V38_000711"
     CDS             complement(19535..20770)
                     /gene="fabF"
                     /locus_tag="L1V38_000711"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBN1315284.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20789..21526)
                     /gene="fabG"
                     /locus_tag="L1V38_000712"
     CDS             complement(20789..21526)
                     /gene="fabG"
                     /locus_tag="L1V38_000712"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBN1315285.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21538..22455)
                     /gene="fabD"
                     /locus_tag="L1V38_000713"
     CDS             complement(21538..22455)
                     /gene="fabD"
                     /locus_tag="L1V38_000713"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1315286.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22562..22786)
                     /locus_tag="L1V38_000714"
     CDS             complement(22562..22786)
                     /locus_tag="L1V38_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1315287.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22839..23801)
                     /locus_tag="L1V38_000715"
     CDS             complement(22839..23801)
                     /locus_tag="L1V38_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBN1315288.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23811..24251)
                     /locus_tag="L1V38_000716"
     CDS             complement(23811..24251)
                     /locus_tag="L1V38_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1315289.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24557..25522
                     /locus_tag="L1V38_000717"
     CDS             24557..25522
                     /locus_tag="L1V38_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1315290.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25579..25809)
                     /locus_tag="L1V38_000718"
     CDS             complement(25579..25809)
                     /locus_tag="L1V38_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBN1315291.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25895..26782)
                     /locus_tag="L1V38_000719"
     CDS             complement(25895..26782)
                     /locus_tag="L1V38_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBN1315292.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26871..28094)
                     /locus_tag="L1V38_000720"
     CDS             complement(26871..28094)
                     /locus_tag="L1V38_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1315293.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28111..29157)
                     /locus_tag="L1V38_000721"
     CDS             complement(28111..29157)
                     /locus_tag="L1V38_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1315294.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29321..31048)
                     /gene="ptsP"
                     /locus_tag="L1V38_000722"
     CDS             complement(29321..31048)
                     /gene="ptsP"
                     /locus_tag="L1V38_000722"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBN1315295.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31048..31314)
                     /locus_tag="L1V38_000723"
     CDS             complement(31048..31314)
                     /locus_tag="L1V38_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBN1315296.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31793..34027
                     /locus_tag="L1V38_000724"
     CDS             31793..34027
                     /locus_tag="L1V38_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1315297.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34175..34495
                     /locus_tag="L1V38_000725"
     CDS             34175..34495
                     /locus_tag="L1V38_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1315298.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34700..34924)
                     /locus_tag="L1V38_000726"
     CDS             complement(34700..34924)
                     /locus_tag="L1V38_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBN1315299.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35122..36702)
                     /locus_tag="L1V38_000727"
     CDS             complement(35122..36702)
                     /locus_tag="L1V38_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBN1315300.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37103..38479)
                     /locus_tag="L1V38_000728"
     CDS             complement(37103..38479)
                     /locus_tag="L1V38_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1315301.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38607..39725)
                     /locus_tag="L1V38_000729"
     CDS             complement(38607..39725)
                     /locus_tag="L1V38_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1315302.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39867..40301
                     /locus_tag="L1V38_000730"
     CDS             39867..40301
                     /locus_tag="L1V38_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315303.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40379..40912)
                     /locus_tag="L1V38_000731"
     CDS             complement(40379..40912)
                     /locus_tag="L1V38_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBN1315304.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41006..42184)
                     /gene="mutY"
                     /locus_tag="L1V38_000732"
     CDS             complement(41006..42184)
                     /gene="mutY"
                     /locus_tag="L1V38_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBN1315305.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42177..42974)
                     /gene="recX"
                     /locus_tag="L1V38_000733"
     CDS             complement(42177..42974)
                     /gene="recX"
                     /locus_tag="L1V38_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBN1315306.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43081..44463
                     /gene="rlmD"
                     /locus_tag="L1V38_000734"
     CDS             43081..44463
                     /gene="rlmD"
                     /locus_tag="L1V38_000734"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1315307.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44637..45215)
                     /locus_tag="L1V38_000735"
     CDS             complement(44637..45215)
                     /locus_tag="L1V38_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBN1315308.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45537..46007
                     /locus_tag="L1V38_000736"
     CDS             45537..46007
                     /locus_tag="L1V38_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBN1315309.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46115..47341)
                     /locus_tag="L1V38_000737"
     CDS             complement(46115..47341)
                     /locus_tag="L1V38_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1315310.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48095..48295)
                     /locus_tag="L1V38_000738"
     CDS             complement(48095..48295)
                     /locus_tag="L1V38_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1315311.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48429..49037)
                     /locus_tag="L1V38_000739"
     CDS             complement(48429..49037)
                     /locus_tag="L1V38_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBN1315312.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49122..49592)
                     /locus_tag="L1V38_000740"
     CDS             complement(49122..49592)
                     /locus_tag="L1V38_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBN1315313.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49640..50554)
                     /locus_tag="L1V38_000741"
     CDS             complement(49640..50554)
                     /locus_tag="L1V38_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1315314.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50700..51503
                     /locus_tag="L1V38_000742"
     CDS             50700..51503
                     /locus_tag="L1V38_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBN1315315.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51681..52628
                     /locus_tag="L1V38_000743"
     CDS             51681..52628
                     /locus_tag="L1V38_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBN1315316.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52696..52989)
                     /locus_tag="L1V38_000744"
     CDS             complement(52696..52989)
                     /locus_tag="L1V38_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBN1315317.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(53017..53682)
                     /locus_tag="L1V38_000745"
     CDS             complement(53017..53682)
                     /locus_tag="L1V38_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBN1315318.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53822..54454)
                     /locus_tag="L1V38_000746"
     CDS             complement(53822..54454)
                     /locus_tag="L1V38_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315319.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54461..55528)
                     /locus_tag="L1V38_000747"
     CDS             complement(54461..55528)
                     /locus_tag="L1V38_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1315320.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55525..56256)
                     /locus_tag="L1V38_000748"
     CDS             complement(55525..56256)
                     /locus_tag="L1V38_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBN1315321.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56425..56904)
                     /gene="greA"
                     /locus_tag="L1V38_000749"
     CDS             complement(56425..56904)
                     /gene="greA"
                     /locus_tag="L1V38_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBN1315322.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57040..58215)
                     /gene="mltG"
                     /locus_tag="L1V38_000750"
     CDS             complement(57040..58215)
                     /gene="mltG"
                     /locus_tag="L1V38_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBN1315323.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT        16798 a        12307 c         9860 g        19348 t
ORIGIN      
        1 aatattcttg gattgcttct cgtgtttttt tcactttttc gctaagcttt tcgtttttag
       61 ccatatagaa ataaaaaatg atatcgatcg tagcaaattg ggccaaaagt gaattagttg
      121 ccgcacttcg attcgtgatt tcttttggtc tagatgtttg tacgagtaca tcggctatct
      181 tgctaagcgg gttatttcca aattgcgtca acgcaatgat ttcgatattc atgcttttcg
      241 ccagctcggc taatgcgact acatctgcac ttctacctga gtttgaaaca agccaaagca
      301 ctttcttttt ctcattgctg acaagttgcg ggagcaagac gtggatatct ttttcaaaaa
      361 tgattggctt accgacacga gaccattttt gcagaatatc ttctactact aaagaagagg
      421 cgccaacccc atataaaaaa acagtctctg ccgattccaa acactctacg actttttgga
      481 tcgtttcttc ttctagaata tctactgttt cttttatcgc tacttgtgca ttgttaccaa
      541 gtttgttttt gatagagtaa aaggactcat ttgcttctat atcactaaaa ccttcatcga
      601 ttccagtctg tagttctgtt gaaatcgtga ttttgaagtc cgtcagactt tgaaaaccga
      661 tttttttgga aaaacgtaca actgtcggcg cactcaaccc ggaagcttct gctaattcat
      721 tagctgtcat tgtagggacc ttctcaatat taccgataat gtagttggcc aacttttttt
      781 ctgctgaaga ataatcttcc atcatacttt caatacgact aattacgctc ataagttcct
      841 ccaccctttt aatgatagtc tatgtaagta taccatatca gacccttatt cacggtcgta
      901 tactggataa aaaacaaaaa aacaatccgc ccaacagaat atcttatccc atcaatccca
      961 cagattctat tgagcatctg tgtctttgag gaatacctgt tatctattgt tcggattgct
     1021 ttctatctac tactttttta caggaaattt acctattagt tttctctgct gtaatttttg
     1081 acttctgctt ccatagcatc aataaagata ttcaaatctt ctacagctgt ttctttactt
     1141 ccataacgac gtacgttcac tgttgcatct tccaattcct tgtctccaac aactaattgg
     1201 taagggatct tttgtgtttg agaggcacgt atcttatagc ccattttttc attacgatca
     1261 tcaacttcta cacgcaaccc cttcatttgc aaacgttctt tgatttcata agcataatcg
     1321 ccatgtgcat caacagaaac agggatgatt gttgcttgta taggtgccaa ccatgttgga
     1381 aaagcgcctt tgtatacttc tgttaaataa gcgacaaaac gttccattgt agaaacaatt
     1441 ccgcggtgga taactactgg acgatgcgta ttttccccgt cttctccaac atatgtcaaa
     1501 tcaaagcgct ctggcaataa gaagtctaat tgtatagttg ataatgtttc ttctgtacca
     1561 agagctgttt tgacttgaac atctagtttt ggtccgtaaa aggctgcctc gccttctgct
     1621 tcaaagtaat ctagttctaa ttcatccata gcggctttca gcattgcttg ggctttttcc
     1681 cacattgcgt catcatcaaa atatttatct gtattgtttg gatcgcgata gctcaagcgg
     1741 aaacgataat ctgtaatatt gaagtcagca tatactgcca ccatcaattc aagcgtacgt
     1801 ttaaattcat ctttgatttg atcaggacga acaaatgtat gaccatcatt caacgtcatt
     1861 tctcgtacac gttgtaaacc tgacaaagca cctgattttt catagcgatg catcattcct
     1921 aattcagcga tacgaattgg taattcacga taagaatgga tcgtgttttt gtagaccatc
     1981 atgtgatgag ggcagttcat tgggcgaaga acaagcattt cgccatctcc catatccatt
     2041 ggcgggaaca tgtcttcttg ataatgatcc cagtgtccag atgttttgta caactcaaca
     2101 tctcccatta ttggtgtata tacatgttgg taacctagac taacttcttt gtctacgata
     2161 taacgttcga tcgtgcgtcg gattgttgcc ccttttggaa gccagaatgg caaaccagaa
     2221 cctacttctg gggaaaccat gaacaagtca agttcttttc ctagtttacg atggtctctt
     2281 tcttttgctt cttcacggag acggatatat tctttcaaag ctttcttgtc aaaaaaggct
     2341 gtcccgtata cacgttgcat catttgattg tttgagtttc cacgccaata agcacctgcc
     2401 actgataata atttaaatac ttgtatacgg ccagtggatg gaacatgtgg tccacgacac
     2461 aaatcgatga attcgccttg ttgataagca gtaatcactt cttcttctgg caattcacta
     2521 atcagttcta ctttgtacgg atcacttgca aaaatttcta atgcttcctg ttttgaaaga
     2581 acacggcgtt cgatcggcag attttctttg acgattttca tcatttctgc ttcgattgcc
     2641 ggcaaatctt ctgcagttac ttggttttgt ccattatctg tatcgtagta aaaccctgaa
     2701 tcgatagctg gtccaacgcc aaagtggata tttggataga ggcgacgcat ggcttgggcc
     2761 atcaaatgag ctgctgaatg acggactaag ccaagtgcat cttcatggtc tggtgtgatg
     2821 atctcaatac ttgcatcttc ctcgattgga cgagtcaaat caacgagttt tccgttcact
     2881 ttaccagcta aagctttttt tgctaagctt tttgaaatgc tttcagcaat tgccaatgtt
     2941 gttgttccag actcaaattc tttgactgca ccatctggaa aagtaatttt tatcataata
     3001 gtttcctcct tgaaatgttt tgattgatca gatcatcaag ctgaaaaaca aaaaaatcct
     3061 agcatctctt gaaaagagat actaggacga aaagttcgtg gttccaccta atgttcaaac
     3121 gcaaatgcgt tcctcaagcg ttgtaacggt ccgaccgccc ttgcttcaac aagggtttcg
     3181 aaagtggtca tcctttggtt ttctcctgga aaagtttcag cctagctttt cctctcttat
     3241 cgaagactct caaattcagt tggctttctc atcaatcaat tatgtgttta tttaaccact
     3301 aataaataga aaaatcaagt gggaaactaa acttattttt tccattcccc atttacaccg
     3361 tatgttcctt ttttcatctc attgatgatg acatggatgt gttcttttgg tgcctgcgtg
     3421 tttttatgaa cagcttccgt gatatctttc atcatatttt ctaattgttc cggactgcga
     3481 ccttctacta attcgacatg tacgaatggc ataatgctct ctcctctttc tgatcgttct
     3541 tttttcaact cgattctatc atactatgtt tgtcttgggt actgaatcag gaaaaatggc
     3601 tggatctttt tttgctctca aggcactcaa aatagagacc gtatccacga cttcttgcaa
     3661 aacagctccg aataatgcgg ggattagtcc cgtacttgca attaacatca aaaaaataca
     3721 aataaagatg ccaatcagta cagactgttt cgctattctc atcgtatctc ttgaaatcac
     3781 tactgctttt gctacacgca agagatcatc tttcaagatg accgcatctg cactttcact
     3841 agcagctgta gaaccatgag cccccattgc aataccgata tctgcagcag caagtgctgg
     3901 tgcgtcattc acgccgtctc ctaccatcgc aacaggtctt tgatctttag ggatactttc
     3961 taaaatggtc agtttatctt gaggcaagct acgggcatgt acagaatcta attggacttt
     4021 ttctgcaatc gtttgagcaa tggcagatcc atccccggtg atcatcatca aatttttcac
     4081 atcaagtttt cttagctcct tgattgtctt tgctgcttct gggcgaatct gatccgaaaa
     4141 taggatcgtt cctgcaaaag atcgatcaat tgttacatag attgctgtat tggacgtttc
     4201 tatttcttca gctgaaacaa aagaggcacg tccaatcttt acttcatgat tattgactac
     4261 tgcttggatt ccttgaccgg tcacttcttt cagttgacta acaggataca gttggctgtt
     4321 tttcacgttg ttcactaacg aacgagctaa gatatggcta gattcctgtt ctgcactagc
     4381 tgcatacaga agtagctctt ctttttttat tccattgact ggctgaatcg cctctacttc
     4441 caatatccct ttggtaagcg ttcctgtttt atcaaaagca atcgtttttg tacgtgcgag
     4501 cttttcaatc gttgttccag tttttacaac gatcccgttt ttacttgaac ggctcattcc
     4561 tgcaactaaa gcaatgggcg cagctagaat cagtggacaa ggtgatgcca ctaccagtac
     4621 ctcagcaaat cgtaaagggt cttttgagaa ccaccaagaa ataccaccga tcaaataagc
     4681 aatcaacgtg aaagggactg cataacgatc agctaaacgg acaaatcggg caggcttttc
     4741 ttttgattct tcgactagtt taataatcat ttgatactgg ctgtctgcgg cacgtttttc
     4801 agcgatcatt tggatcgatc cgtctccatt taaagaccct gacataatct gatctccagg
     4861 tttcttggtt tccgggcggg actcacctgt caaagaagat tcatcgaccg aagattctcc
     4921 tttggtcact cgaccatctg cgggtacaag ttcgccaggc ttgactagta actggtcatc
     4981 aatatttatt tcatcgatta ctatatcctg caattttcct tctttgaatc gatgggcaat
     5041 tcttggggtg ttatctaaca aagactgcag ttctttaccc gctcgtttat tcgcgtaatc
     5101 ctctagacta tctccgcccg taagcatgat caatatcatc aaactagccc agtattcttt
     5161 gacggctaat gttgcaagga ttgcggtaat cgctaataca tctacgccat atcttcctga
     5221 acgtaacgtc ttgatcattt ccaaaaacat caagaaggcg agaatccctc cagtaaatgc
     5281 gacaatcgca aatgcaaggg ccggctggtg aaaaacaaat tcacttaata aagctatccc
     5341 accaataagc aaagtaagta aaaatttttt gaaatgtgtc attgtttttt ctcctctttt
     5401 atgtgactta gagaggttag taataaattt ccagctgcct ctttcatctt aagcatagtc
     5461 cttgactagc actttttaaa acaataggcc ttaattgaaa acaactatca ctatcagcgt
     5521 ttccaaaatt catcagttct acaaacaaaa atattcagca aggattactt tttcgattca
     5581 tcagttaaaa agtacctttt ttcgaaaaac tatgctatac ttttaattcg ttatttacgg
     5641 cggaaggagc aaacatgcga tgaatgagaa acaactagaa caaacgcacg tggatgaaac
     5701 gatcgaacta atccagatcg aacaaaatat gctggataca aaacaacaag aattgactca
     5761 ggaaatgaat cattcgacaa aagacacagc taatcacaag attcgagctg gttccaatga
     5821 agctttttat gaatctgctg ttgaatatcg ccaacatgag caggaattgc ttttgaaata
     5881 ccatactctt gaagcacagc aaaaacgcct gcaaacgttg tctgtcatga aagatagtcc
     5941 ttattttgcc cgtatcgact ttaaagaaga ccgtgaaaca gaaacattat atctaggtat
     6001 cgcttcttta agagatctgg cagaagaaac aatcgttatt gactggcgcg caccaattgc
     6061 caatctttat tatgaaggtg agattggtcc cgcattttat gaaactgaaa cagatagaat
     6121 agatgtcgat ctgcagttga aacgacaatt taaaatccaa gaaggacgta ttttatctat
     6181 ggtagatacg tcggaagtaa tcaatgatga ctttttgcta gagatattgg atgaatcatc
     6241 aagcaaccat atgaaaaaca tcgtctctac gatacaaaaa gcacaaaatg caatcattcg
     6301 ggacacaaca agtaaagtaa tgctgattga aggaatcgcc ggaagtggaa agacatccgc
     6361 tttgcttcaa cgtattgctt ttctgttgta tcataatcgc aagtggctcg aggctgaaaa
     6421 cgttcttcta ttttcaccca accatttgtt ttctgattac atctcgactg tattgccttc
     6481 attaggtgaa agcggcgtgc ctacacagac attcaaaaat tatttggtgc agctgctgcc
     6541 agagttttct ttactagatg aacagcaaca agaaagtggt tttttgctag gggaaaaaga
     6601 tccgatacaa gtgatgaaaa gcggattgac cttagtcgat cagattgatc gctatatcca
     6661 aggcatcaca aactacggtc ccttgttccg tgatatgaaa ataaatggcc gtacgatcct
     6721 atcaaaggaa tcgattcgcc aatggtataa agaaacaaat gaacaattac ctttacatca
     6781 tagactttct ctattacaaa cgaagctcct gaaaaaatta ggcggtctgc aaaaagacga
     6841 aacacgtcag caatgggtca aagatctggc ggaagaacag ctccaagaac tatacgcaac
     6901 agatccaaat cttgaatata cagaacaaaa ggagcgttca ttacgtaaaa aactggccaa
     6961 ccaaatcgta cgtaaaagat tccgtcgaat ccatcgaggg atcatgaatt atcaatttgt
     7021 caatataacg aaacaatatc tccactttct acaaactgtg ccactttctc ttctaacacg
     7081 acataaaatc agcgagacca ggtggcagga acatttgaca actgttcgta cacacttgcg
     7141 tcaaagagaa ttgcgtcaag aggatgctgt actattcttt ttactgatgc gccgaacata
     7201 tccagtgacg gttacacaca aagctcgcta tatctttatt gatgaaatgc aggatttcgc
     7261 accatcacaa gtggcattgc tgcaagcctt gttcccaaaa gcaaatttga ctttctgtgg
     7321 agatctaaat caaaatgtct ttggaaatga aacgatcgtt ggatcattgg aagacctttt
     7381 cgtggaccgt gaagtcactc gtttccaatt aacgacaagc tatcgctcca caaaagaaat
     7441 cactgatttt gctaatcatt ttattgtgaa agaacatcaa gtagaaacaa cagcaagaaa
     7501 aggagacctt cctttgctca tccaaggaac aacagatgat atcaaattga attggttagc
     7561 agataccatt cgaacgactc agggaaaagc ccggtattgg cgtacagcaa tcatagctaa
     7621 aacacaagaa gaatgcgaag ctctttatgc tcaactgcca gacgagttga aacaacaagt
     7681 ccagctgatt ttaaatgaga gtgactttat gaagcgttcc attattttac ttccagcctt
     7741 tttagcaaaa ggtctggagt ttgaccgagt tttcttgtgg gatgtagatg cagaacattt
     7801 ttcttctcag caagacaaat tgatccttta caccatgtgt acacgtgcga tgcatgaatt
     7861 gacccttttt acctccaata atgaaagtcc tttgttaaac aatatggata tttcatctta
     7921 tgagaaaaaa gtactgtaag taaaaagaca actgctatca ttaatgttag cagttgtctt
     7981 tttatttaca ataataattg cagaaaaagt aattcaatca tttaaggtca tttattctat
     8041 atataaatcc aaatctgttt caggatattt taatttgaca agcgaaataa tcattttcag
     8101 ttcttccatg ttttctggat attctgggtc aaataccttg ctatgacggc caatcccgcc
     8161 attgtcgatc aatcggtaaa ttcgattcca ttcaatgaat tggtcaattg attggaaatt
     8221 gctgattgga tagccgccac aatccaaaat ctctgataca cgaaatgcta ggtatgcact
     8281 atcgatcact ttattttttt tcgtgtctat cttctcattt ctttcgataa gaattttttc
     8341 aggacgatgt ttcaagctcc actctaatag tagaaagaaa gcctccatcc gatactcttc
     8401 ttcaaataac cgaaaggctg aatcagaacg acgaaaaagc agcggaatca gataattttg
     8461 tctataaatc agcattggtg cgcggtccac catacactct aaataacggt tcagataccc
     8521 tgtaccgaca tagtttccta atcgatagcc ttcaacgccg aatcttgcgt atttttgcgc
     8581 taattttgaa caatcagtta cgttcacagc taactcttct actttgcggt aaccgcttaa
     8641 gatacgttca aaaggttcta aagtgatttt tgcttccata ttcttccccg tccatcttcc
     8701 acatacttca tatcatttca catgatactt atgctctcat cataccacag gttgaattag
     8761 aaaagaaaat aaatcacaca aaaaagcaag acaatctgtt agtgagattg tcttgctttt
     8821 cgaaaaagac tgaatacttt tcgttaaaac tggttgctta gtcttctaat gccacattat
     8881 ggaacacatg ctgtacatct tctagatctt ccagtgcatc aatcattttt tcaaatgttt
     8941 cttgatcttc tggagatagt gttacctcgt tttgagggat catttggatc tcagcgattg
     9001 aaaaatcagt gattcctttt tcttttaatg cttcttgtat actatggaaa tccgctactt
     9061 caccgtaaac gatgatttgt ccttcttctt ccattacatc gcgaacatcg atgtcttttt
     9121 ccattaggta ttcaaggatc tcgtcagcgt cttctcctgc aaaagcaaag attgctgtat
     9181 tgtcaaacat gtaagaaacc gctccggaaa cacccatgtt cccgccattt ttcccaaatg
     9241 ctgcccgtac gtctgctgct gttcgattca cattgttcgt caatgtatca acaatcacca
     9301 ttgagccgct tggtccaaat ccttcatagc gcaattcaga gtatgtttca tctcctgcac
     9361 cttttgcttt ttcgattgct cggtcaataa tatgttttgg tacattataa gttttagcgc
     9421 gatcaatgac gaaacgtagt ttttggtttg catgcggatc aggatcacct gattttgctg
     9481 ccgcgtagat ttcaatccca aattttgcat aaatccggct attattagca tctttagcag
     9541 ttttctttgc tacgatattt gcccatttac gtcccatatt ttcacttcgc tttctgattt
     9601 gatagtttca taacgcaaaa acgtcctgtt ccattatact tgtgaatcac gattctgtga
     9661 agcttttttt ctttcttcct tcattcttct catttttagt caattatcta tactcggatt
     9721 gggatttgcc cgaaattctg ttccggaata ttgcctccca attgatagat ttgatcactt
     9781 ctaactaaca gttccgcttc ttgtgcctct ttttttccga ttcgggaata aatagaaatc
     9841 tctttttttt cttttaagaa tcttcttcca gcatcggtaa atccaagtag tcgaagataa
     9901 tttttatttt gttggacagg aatctcttgc tttttgatat tcagcaagac ataacaagat
     9961 aatcgttgga tccgtgtcca tgtatatctt tttgttttta cctttgacac aaaatcctca
    10021 aaactatcag cagttgcagc tgctgttttc atgcgcgatt ctattccttc ggtcatctga
    10081 tagatatctg tcagttccag caaagtagaa gataacaacc gataacgcaa atacggccaa
    10141 taagattccc aagtctgcag cgaacaagtt gaaagatctt cttctgtctg aggcggcaca
    10201 agtccagcta ttctttttcc ttcttctaac gcatggcgaa tggctgttgc actggctatc
    10261 ctctgatctg tgatgatttt ttcatgatag cctgcacttt tacgtcggat cggatgtaat
    10321 tccatagggt ggacatactt ggcattttcc tttgcataac ttaatcccaa gatatgattt
    10381 ggcgaagaaa aatcaagcgt aatatcggga tacagactgc gaaaaacctc agtcattttt
    10441 tgcggataac tatacgtttg atcagacagt tcttgaaatg cctcttctat cctatcttga
    10501 ttctcttgga caaagcgtcc gaaactgctg taatcaaacg aagtctcttc ttctgttcca
    10561 aaacacaaac tgtcacagtc cagtgtttgc aagattttta ctgcaccttt agcaaaatag
    10621 tcagctgact gaaccgccca ttcgacggga agctccacta ctaaatccac accattttgt
    10681 aaagcttcat tcgcgcgatg ccatttatcg atgatagccg gttcgcctct ttgcaaaaaa
    10741 ttcccgctca ttacagcaat gacgacctct gctcctgtta tttttcgtgc catttccaca
    10801 tgatagcgat gtccattgtg aaaaggattg tactctacga taatcccgca gcttttcatg
    10861 cgcatcctcc ttcatagtta tcgataaaaa agaaatagag acaagtaaaa aaaggcaaaa
    10921 atcggaaaaa atacccgaac tatataaact attctcgcaa acacaatact tctgcgacga
    10981 aaagctgcac tgcaagagca atgcctatat cgttcggata tataatttat gttgaagatt
    11041 tattcttttc ttgttaactc gagcaggcaa aaccgctagt ctttgtatgc tacaaagaac
    11101 cagcgctttg atttctctga tgctgcttcg tctgtaaaat cagaaaatgc ttcgactttc
    11161 gaaaagccgc tgttttccag cattcttaaa taactttcca atggataggt acgctcttga
    11221 tgtagttcat cttcacgaat aaatcgacca gacccttctt gttcttcaac gaaaaaggta
    11281 agaaaatgtt cgatgctgtg tttctcgctt cctggataac tatcccacaa aaaagcaaaa
    11341 ttatcccctt gataatgata gctatattct ggaaaaacct catctacttg ataggtggag
    11401 tgtacgtcaa ataaaaatcg gccattttct tctaacgctt gatagacttc atcaaacact
    11461 tgctgtacct cttgtctatt tttcatatag cacagcgaat cagaaaaaca ggtaattgcc
    11521 tgatattgtc cgatttctga taaatcgagc atattgcctt ccacaaattg gatcgatgcg
    11581 tcttcttcat atgctcgctg gctggcaatc atcaacatct cttctgaaag gtctaaccct
    11641 gtcactttat atccatcttt tgcaaaggca accgctaatg ctccagtacc gcatgccagt
    11701 tccaaaatat tttttgtgtc ttcttgtaaa tgacgtttcg aaaaagctaa ccattgctga
    11761 taaagtgttt cgtccatcac ttcatcgtaa atgaaagcaa atgtttcata agccatatgt
    11821 taatccaacc attcactaag atcgactagc ggagcatctg accatagttt ttccagatta
    11881 tagaaatttc gttctggcgc atggaaaaca tgtacgatca catctccaag atcgatcaat
    11941 acccattttc cgccttcttt tccttcaata cgttttactt catatttgtt ttcttcttct
    12001 ttatcaatga tttcttctgt aattgcgttg atttgacgtt cgctatttgc tgaacagatc
    12061 atgaaataat ctgccaacaa ggaaacattt cgaacgtcta aagcgataat gtcttctgcc
    12121 cgttttgaat ctgctgcttc aatcgcaatt tttaattgtt ctttactatc tatgatgatt
    12181 tcctcctaat atgagcagct tatttttttg ctacccagta attatatgtt tcgattgttt
    12241 ttggataaat ctgttgttct tgcgcaagca aatgggccaa tgtatgtttt gtttcaaatg
    12301 ctacagcttc gtctagatca gcccatgcaa tggctcgtgc atcttgtacc ccaggaaaat
    12361 ctcgacctgg ttcaatatag tctgctacat aaatgatttt gtcaaggaga ctcatcttag
    12421 cagccccagt cgtatgcacc cggattgcat gaagaatctc tgcatcggtg attcctaatt
    12481 cccgctctac aaacgaagcg ccaacaagac catgccagat tgcattatta taattcaata
    12541 actccggatc aaaaccgtct cttacgatta ccattttgaa ctcctcatct ggtcgttctt
    12601 ttgcataatc atgtgtcaat gcagcaatac tagctttttc aggagaagca ccgtattttt
    12661 tggcaagagc cacggctgtt tcttctactc caagcacatg cttgaagcgt tgttcgctca
    12721 ttctcatctg tattttttgc atcaggtttt ctctagaata agcagtatat tcattactat
    12781 agtccatatt catacaaccc ttcattttga atataatcaa ttactttatc tggaacaagg
    12841 tagcggatag aacagccttc tttgatcttt tgacgtattt tcgtggaact gatgtcgatc
    12901 tcaggtacat ctacccaaat tacaggatat ggagtatccg ttgtgtatcc tggtcgacgt
    12961 atacccacaa agttgaccat agaagtcagc tcatcgattt tataccattt tggcaaatat
    13021 tctaccatat ccccaccgat aataaagtaa taatctgtat ccggattgtt ttgcgtcaat
    13081 tccttcatag tatcataggt gtaacttttc ccaccacgag ctaattcaat cgtttcaatc
    13141 tgcaaaaaag gattgtcttc caccgctaat tccaacatgt tgagtcgatg ttttgcatca
    13201 atcgtctgtt tctcatcaac atgaggtggc tgataagaag gcatcaaaaa tacgcggtca
    13261 agacctaaat tccggccagc ttgttcagcc atcactaaat gtgcaaggtg aacgggattg
    13321 aatgttccgc ccaagatccc tacttgcttt ttcttctcta agaattgagg catttcttca
    13381 ggaaataatt gtgaacgaac aaatgtctta gcttgcgtat tcatcatggt cactccttat
    13441 attgctttta cttcttttga tagcctttga tacttttctt ttgtggaagg tttgtataat
    13501 acaataacac gtccaatgat ttggacgatt tcgcaatcta tttctttttc taatacttga
    13561 gctgcttctt ctgcaatctc atctgtattt tgaagtaacg atactttgat cagttctctt
    13621 ttttctaaag cttcttcaat ttgaacgatc attgctgaat tgatcccacc ttttccgatt
    13681 tgaaaaatcg gctgaagatg atgcgctttg ctacgtaaaa aacgcttttg ttttcctctt
    13741 aaactcataa ttttccttct tccttaaatc aatgctttgc gtttcaatac atctacaccc
    13801 tttggcgccc agcccgcaat tactactggc gctgttacag tgatccagcc tagaccggca
    13861 aaaacgatgt ctgttttttc tttcacagaa aactcaaaac gaacaagctc cggaaatgcc
    13921 tcgacttcat caggacgagg aggctgtaat aatccaccta catgtttttg ataaaattcg
    13981 tctgcttttt ccagtttcgt tcgatgaata tttacatcat ttgacacata agcaataaat
    14041 gaagcacgat tgccgctgat aaaatcaaat cttgcaagtc cgcccaagaa aagtgtttgc
    14101 ccttcattca gctgataaac tttaggtttg atttctttta acggtgcaat gatccgcaaa
    14161 tcttttttac ctaagtagtg cgccatttga tggcgatgga taattcccgg tgtatcaatc
    14221 aaaaaatgcc cgtcatctaa aggaatctcg attttatcca aggtcgttcc tggaaactgc
    14281 gaagttgtga ttacatcttg tactcccgct gtatttttga tgatttgatt gataagcgtc
    14341 gattttccga catttgttac tccgacgata tagacatccc gtccatcgcg gtattcttcg
    14401 attttttcta atagttccgt catctcatga gatttcttag cactagttaa taatacatct
    14461 actggacgaa ttcctgcttc gtaagcacgt tccttcatcc attgtgttaa tttagttttt
    14521 ttcaatgatt taggtaatat atccactttg ttcccaacta aaagtactgg attgtcaccg
    14581 acaaaacggt gtagtcctgg gattagtgaa ccattgaagt caaaaatatc caccacattg
    14641 acgatcaatg catctttttg ccctaattca ttcagtaagc gcaaaaagtc gtcatccgtc
    14701 aatgagacat cttgggtctc attataatgg cgtaatctga aacaacgctg acaatagact
    14761 tccccggaag ctaaaccttt ttccaaagcc gtttgcggcg tgtatcctaa ttcaccgggt
    14821 ttgtttgttt gtataacggc accacagccg atacattgta attcttctgt cattcgattc
    14881 cacctcgcca gcccatatca gggtgttttg ctaatagata ggccataatt cttttttccc
    14941 aaaaacgatt aaattgtgtc ttccaactat ctgttgcgat aatgggtttt acaaggatgc
    15001 tacgtatccc tgcacgattg gctccacgta tatcagtcat aatctgatcg cctaccatta
    15061 ctatctcatc atctgctaaa tccaattgtt tctttgctat gttgatccct cttgctaaag
    15121 gtttcattgc tcgtgcaaca tacaaaagat caaatttttc aatcgctcgc gcgacacgtt
    15181 ttgaattatt gtttgaaaca acaacaacag ggattcctgc atttttcatt tctaaaatcc
    15241 aagtaagcaa ctcttctgtt ccatctggat tattccatgc aatcaacgta ttgtctaaat
    15301 cggtcaatac tgctttgatg cctagattct ttaattgggc aggtgtaatc tgatagatgg
    15361 cttctaccat ccatgttggt ttgtaatttg aaaacatgct gtctcctcat ctgcaaaaaa
    15421 tgaaggagca cataaagtac tcctcaaccc cgtattatac tgcatatcag caaaaaaaac
    15481 tacctctata ctcgttcgtc tttcagaaaa agcatttctt tacaaaatga ccaaaaataa
    15541 agattgatca cagaaaaatt tagaaacaaa aaacaactaa tattggcgga acctcttgta
    15601 tcgtttttcc agtaatttat gctgatctaa tcgaacaagt tccgtcaatc tttcaatcaa
    15661 cgcttttttc ataatgtgtg cgactttata tcgtggcaac tgctcgccgt tgaacgtttc
    15721 aggaataact cgatcaacga ttcctaactc gcgtagttct ggcgcagtaa ttttcatcaa
    15781 ctcagctgct tctgcggcgc gactaccgtc tttccacaaa atcgacgcaa atccttctgg
    15841 agaaagcaca gcataaatcg tttcttccag catccagact tcatccgcta aacctagagc
    15901 aagggcaccg ccacttccac cttcaccaat gatgatggcg atgatcggta cctttaaatc
    15961 agacatttcg agcagatttc tggcaatagc ctctccttcg ccgcgctctt ctgctcctac
    16021 accgcaatat gcacctgctg tattgatcaa ggtaatcacc ggtctattga acttttccgc
    16081 ttgtttcatc agtcgtaaag cttttcgata gccttcagga tggggagaac caaaatttct
    16141 gcggatattt tcctgcagat cccgtccttt ttgaataccg atcactgtta ccggtttgcc
    16201 atctaatcga gcgattccac caacaatcgc ttcgtcatct gcaaataaac gatcaccatg
    16261 gcattcctcg aaagaatcga agatctcttc aaaaaaatcc aagcttgtcc atcgttcttt
    16321 agctcttgct aactgaacga catcatgtgc tgtcttatcc acgatctatc catcctttct
    16381 gtgtatgcaa ttcaagaagc gtatggattt tctgtttcaa ttccatgcgg ggaacaatct
    16441 gatcgacaaa accatgagat aataagaatt cagccttttg gaaatcttct ggaagttcct
    16501 gcttgatcgt ctgttcgatg acgcgtcttc cagcaaaacc gatcaagctt tggggttctg
    16561 ctagaataat atcgccttcc attgcaaaac tggcagttac tcctccggtc gtcgggtccg
    16621 ttaaaacagt tagataaaaa agaccttcat tgctatgccg tttgacagca gcagagattt
    16681 ttgccatctg cattagagaa aagattcctt cttgcatccg tgcgccacct gaagctgtga
    16741 acaagacgac tggaagactt tcctttgttg ctcgttcgaa taatctggtg atcttttctc
    16801 cgacaatcgt tcccatactt cccatgataa aattaggatc catcactcca ataatgaagg
    16861 gaatcccctg aatggttgct ttaccagtga ggactgcttc atgaagtcct gttttatctt
    16921 gcattttttt aattttttcc gtatattcgg gaaatgctag cggatctttg gttacaagat
    16981 ccgtatccca ttcttcaaaa cttttttcat caataatcaa agctagacgc tgccatgcac
    17041 cgattcgaaa agcgtatccg caatgagggc atactttttc ttcaccgatg tctttcgtat
    17101 aaaggatatg tttgcaattt ggacactttg cccacatgtt atcaggaaca gatggcgagt
    17161 tagcaggttt gctctctcta ttaggattga tccgaatata tttctttttc ttaaacagag
    17221 ccatctatgc gcctcctatc tccgtttctg gtgtccaatt cggtaaaaat tcttcttgta
    17281 aaaatgctgt gctgtaatca cctgctatga ctgcaggatg actaatcaaa tccatctgaa
    17341 attctgcgtt cgtgatgatt ccttctgtga taaattcact taaggctcgc tgcatcttca
    17401 ttaatgcttc aaaacgcgta tttccatgga cgattatttt tgcaatcatt gaatcataat
    17461 atggcgggat cgtatatccc gggtaaactg cactgtctac tcgcagtccc atcccacctg
    17521 ctggaagcag taagttttgg atcttccctg gagaaggagc aaaatggaaa gcaggatttt
    17581 ctgcattaat ccggcattcg attgcgtgtc cttggaatac tacttcttct tgacacacat
    17641 tcaaaggctc accggctgct atctccacct gtttttttac taaatcgatt cctgtgacca
    17701 tttctgttac tggatgttcc acttggattc gagtattcat ttccatgaaa taaaaatcgc
    17761 cttcttcatc catcagaaac tcgatcgttc cggcattttc ataattgact gctttagctg
    17821 ctcgaacagc agcgtctcct agtgcttctc tttttgtttg tgagatcact acagaaggag
    17881 attcttccag tactttttga ttgttgcgtt gtaaagaaca atctcgctcg cctaaatgaa
    17941 tgacatgacc aaatcgatca cctaagatct gaacttctat atggcgagca ggataaatga
    18001 ttttttccaa atacatatca tcatttccaa atgccgctgc tgcttcttgc tgagctgaag
    18061 aaaaatgctg tgggagctct tcttttgatt gaactttccg aatgcctttc ccgccaccac
    18121 ctgcagctgc tttcagcatc actggataac caattctgtc tgctatttcc aatgcttctt
    18181 ctactgtaga taatacacca gtacttcctg gaatgactgg gacatttgct tcttgcatca
    18241 attgacgcgc attgatctta tttcccattg catcgatcgt tgcactttta ggaccaataa
    18301 atgtgatatt gcactcttca cacatggagg caaatcggct attttcagat aaaaaaccaa
    18361 atcctggatg aattgcttcg gcttttgtca cgattgcagc gctcagtact tcctgaacat
    18421 tcagatatga atcaacggct tttgccgggc caatgcagat tgcttcatct gctaactgtg
    18481 tatgaagtgc ttcggcatct gcttctgaat atatcgctac ggtttggatc cctagttcgc
    18541 ggcatgcacg aatgatacgt acagcgattt caccgcggtt agctatcaat actttagaaa
    18601 acatatttca cctatccaat cataaaggtt aattccgctt cggctacttt tttaccgtct
    18661 actttagcga ttcctttgcc tattccggct gaagctttca ctttcaatat ctcaacttca
    18721 aggtataagg tatctcccgg tgtaactttc ttacggaatt ttgctttgtc caatccgccg
    18781 aaataagccg tctttccctt gaattgttca agagaaagta atgcaactgc tcctgcttga
    18841 gccattgctt caacaatcaa tacccctggc ataacaggtt cttctggaaa atgtccttga
    18901 aaaaagggct cattgatcgt tacatttttc ttagcaacga tccgttctcc ttcaaccatt
    18961 tcttccactc gatcaatcaa aagcattgga taacgatgtg gaatgatttc ttttatttct
    19021 tgtatgttca ttgttttccc tctttcctgc tttgcttatt tttgctgaat cctaaagagt
    19081 ggctgtccat attcgacaac tgactcgttt tctacaagga tttctgtgat cactccgtcg
    19141 gcctcactag ttatctcatt catcagtttc atcgcttcaa taatgcagat aacttctcct
    19201 ttggcaactt gatcacctac ttttttgaaa gctggtttgt cgggcgctgg ttgcagataa
    19261 acgattccca cgattggcga aacaacctcg attccatcaa atactgccga ttctttttct
    19321 ttcattattt ctggagcagt tgttgcttgt tcaggtatga cattgactgg ctccgaaact
    19381 ggcaacgttt cgtttgtttg aaccatattc atgcctcgac ttgttttatt tttattcata
    19441 tacaattcaa attgaccttc acgcaaatcg aattccgtta gcgaggattg atcaaattga
    19501 ctgactaatt ctctgatttc attgatatcc aaaattattc ctcccagcgt ttcatgcaca
    19561 gaaccgcatt atgtccgcca aaccctaatg aattactcat tgcataagta aaacttgcag
    19621 gtttgctttc gtttttgaca actgtcaagt caatctcagg atcttgtttt tctacattga
    19681 tcgtaggtgg gataaattga tgttctaatg ccagcaaagt tgccaaggct tcgatcccgc
    19741 cggctgctcc caataaatgt ccagtcatcg atttcgtgct gctgacgtaa gtatctctga
    19801 aattttcacc taatgcgatt tggattgctt ttgcttctgc ctggtcattg gctggtgtac
    19861 ttgttccgtg agcattgata tatccgactt gttccggctg tacaccagct tcttccatcg
    19921 caagcttcat tgctttagat gcaccagaac catctggagt aggagctgtc atatggtaag
    19981 cgtcacagtt tgcaccgtat ccaacgattt ctccatagat tttggcaccg cgagcttgtg
    20041 catgttctaa agattcaaga actagaacgc ctgctccttc acccatcaca aaaccattcc
    20101 gattttcgtc aaacggaatc gaaccacgat taggatcagt tgattctgag agtgctgtta
    20161 aagctgcaaa tccagcaatc cccatctcac aaatcgttgc ttctgttcct ccagcaagaa
    20221 tgacatcaga atagccatgt ttgatgttac ggaatgcttc cccaattgaa ttcgttccgc
    20281 tagcacaagc tgttacgata gctgtacaaa taccttttgc acctacacgc aaagcaatat
    20341 ttccagctgc catgttggca atcgccattg gtacgaacat tggagaaact cgttttgcac
    20401 ctttttcatg tagacgaata acttggtttt cgattgttgg aagaccaccg atcccagatc
    20461 cgatgatgac gccaaaccgg tcttgattca ttttttcttt atctaaaccg ctcatctcca
    20521 ttgcttctaa agcagcgtag attccataga tcgaaaacat atccattcgt ttgctatctt
    20581 ttttaataaa atatttatcg taagggaaat ctttgacttc acccgctaag gtaatccctg
    20641 tttctgaagc atcaaattta gtgatcggtg cgatgccatt cgtcccctct tttaagctat
    20701 tcaaaaagct gtctgcgtca tttccaatag gtgaagtgac tccatagcca gtaattacca
    20761 ctcgattcat ttgtttgctc tccttttctt atccgtgcat gaccaatccg ccatcgacat
    20821 tgatgacttg tccggtgata tatggatttt gtgctaagaa aactgctgtt tgtgcaatat
    20881 cttctacttg tccgaaacgc tgcatcggaa tttgcttttc cgcttgttcc ttgactttgt
    20941 ctgctaaaac ttccgtcata tcagttgtga tgaatcctgg cgcaatggca ttacatgtaa
    21001 tgcctctagt tgcagcttct cgtgccacag attttgttaa tcctactacg ccagctttac
    21061 tagctgcata atttgcttga ccaatatttc caatcaaccc agatacacta gagagattaa
    21121 tgatggcccc ttctcgctgc ttcatcattt ttttcaatac gtgctgcgtc atattgaagg
    21181 ttccaatcaa attgatatcc agacattttt tgaaatcttc tgcatccatt cgcatcacaa
    21241 gtttgtcatt tgtgattccg gcattgttta ctaacacatg gatcgatcca agcttttctt
    21301 ctgcttcttt gatcatttgt cccgctttct cataatcaga gatgtcaccg gaaactccta
    21361 cgcattttac accgaatgct tcgatttctt ctatcttttc ttttggaatc tctccgcgac
    21421 cattcaaaat gatatttgct ccagcttttg caaaagctaa ggccatcgct ttgccgattc
    21481 ctcttgtact acctgtgata aatacatttt ttccttttac atccataacg ttcctcctta
    21541 tagtattgct attgtttcat caaatgtctg cttattctca acacgcagaa ctggtattgt
    21601 tttatcgatt tttttcataa atccgcttaa tacttttccg gggccgactt cgatgacttg
    21661 ttcgatgccg attgttttta acttatggat actctcatag aaacgaacag gttgcatgac
    21721 ttgctgttca agtagtcccg cgattgtttc tttcttcatt atttccgttg ttgtgttgct
    21781 tatgatagga aaagaaggtt cagagaattg aatctgactt aggtccttcg ccagtttttt
    21841 tgctgccggt tctaaaatag ctgtatgaaa aggcccgctg acatttagag ggatcattct
    21901 tttgaaccct ttttctttta atagtaaaac agcttcgtct actgcttttt cttcgccacc
    21961 aatcacgatc tgctgaggtg tattataatt tgcaggagat acgatgccgt acttgctagc
    22021 ttcatgacag ctttcctcga tcgtttcaat cggcgcattc atcactgcaa ccattttccc
    22081 gcttccagct ggggcagctt ctgtcatata agcgcctctt tttgctacta acgcaactgc
    22141 ttcagtgaag gatagcgcat tactagctac taatgccgaa tattctccta aactcagtcc
    22201 taaagctgca tctgggatga ttccatgctc cttcaataag cgataatacg cgatgctgac
    22261 tgttagaata gctggctgtg tatattgcgt ctgatccaaa cgttcatttt ctgtaaagca
    22321 aagttcagcc atatcgtagc cgagaatctc acttgcttca tcaaatgtct gctttacaac
    22381 ggcttcttca tataaatctt ttcccatacc ttgatattgt gcaccttggc cactaaataa
    22441 gaatgctgtt ttcatgtttt tctccaatat atccagaata tatgtttgat tcttcctatt
    22501 caaaaaggcc gagacattcc tatttcagga aatgtcccag cccccaacct aattttaatg
    22561 attatgcagt ttgtttttct acgtaagtca ctaaatcttg aaccgttttg attccgtctt
    22621 ctgtttcgat tttcacgtca aattcatctt caatttcatt gatgatttgg aataaatcca
    22681 agctgtcagc ttctaagtct tcttggatgt cagtagtcaa tttgatttct tcagtttctt
    22741 ttcctaattc ttctgcgatg atttcttgaa ttttttcgaa taccataata atatattcct
    22801 ccgatattgt ttgcttttta tttttataat ttaacagtct acaactccat gagaatactt
    22861 ccccatgtta aacctccgcc atagcctgta aatattactt tctgctgttt tcctaaggtg
    22921 atctttccac tagaaactgc ttcatccaat aagataggga tgcttgcagc agatgtattc
    22981 ccatatttat ccatattggt caggaacttt tcttgcggca tctttacttt tcgggcaatt
    23041 ttctcaataa ttctgaggtt tgcctgatgc aaaagcagat aatcaactgg tttgtctttc
    23101 atgacttctt ggatattgtt tgcaacgtct cgtacggcaa aatcaaaaat atctctgcca
    23161 gtcatttgca aataatacga accttctgaa tcttctgaat agaacggatt tttattttgc
    23221 tggtagccag cggtcaatga gctacttctg gtaccgtcag ctgctaattt ttctttcagc
    23281 aattttttct gtggattcgc ttctaagaga atcccacctg ctccatcgcc aaacaacaca
    23341 gcagtcgtac gatcagacca atcgattagc ttagatagtg tttcaccacc aatcaccagt
    23401 cccttagttg agccgcagcg gatcattttt tcagccatgc ttaacgcata aacaaatcct
    23461 gagcacgcag cactgatatc aaaagcgata gcatgagttg ctcccaattt cccttgtact
    23521 tgtgctgcta cagatggtgt cgtgtaatcg ggcgacattg ttgctactaa aataaaatcc
    23581 aaatctttag ggtttagatt tttctgtttt atcaattttt ccgccactaa aatgcataaa
    23641 tcagaagtct cctgatttgt tacacatctt cgttcacgaa tacccgtcct tgacgaaatc
    23701 cattcatcag aggtatccat catcttggaa agatcattat tagtaataat cttttcagga
    23761 aggacgctgg ctgttgcagt aatcattcca aattgttcca ttaaatatcc tcacttatag
    23821 tcttgcaaga agtcgtgcaa gtttttcagt gcatccagca aggcatgctg ttcctccgta
    23881 gccattccgt ctaagatgtt cttgaccatt tcacgatgaa aatgctgatg gacccgaaat
    23941 agtaactttc cttttttcgt tagtcccaac tttacaacgc ggcggtcatc ttcactgcgg
    24001 atacgttcga catagccttt ttttactaac ttgttaatag cagtggtcaa ggtcccaaca
    24061 gtaattgata gttctttggc tacttctgaa gttgtttttt tcttgtacat cccgattgcc
    24121 tcgatcgtgt gcatctctgt gattgacaga tctttgaatt gagatttttt cagctcagac
    24181 tcttcgattg tcaaaatatc attgaagaca ctaacaagat aatcatttac tgtttttaaa
    24241 tctggttcca tgttccaccg tccactaatt agtttgatta tcaaatcttt tgatgttcaa
    24301 actatatctt aacttttttc aaaatgcaac cttaaaagat cattttttta ctatatgagc
    24361 tttttttaag attttactca tttaaaacaa ctgataaatc agcatttata atttctttta
    24421 ttagaaaaat catctatctc acatattttg attatcaaag tattttctgt gaacagaact
    24481 atagaattcc ctaaaacttg tccattattt caaaatttgt tatagtcttt ttattcaaag
    24541 cgtaaaagga gatcctatgt taaaagaaaa aatgaaaact ctccccatgc tgccgggtgt
    24601 ctatcttatg aaagaccgag atggtaaggt catctatgtt ggtaaagcaa aacggctcaa
    24661 aaatagagta agcagctatt ttcatcagaa taaacagcat tcaaaaaaag tattacgtat
    24721 gattcatcat ataacagatt ttgatttcgt cgtagtagac acggaattag atgctttatt
    24781 gctcgagtgt caattgatcc aacattaccg tcctttttat aaccgacaaa tgaattattt
    24841 cagtaattat aattatgtac atattaccaa taagggattt gtattaacag atactcctac
    24901 ggctcgaaca tacgggcctt ttcgtctcta taaaaaaatg ccgtctattt tgcgtataat
    24961 ggaagaaact tatcaaatgc cttggttgtc tgaaattagt ttgttagctt tgcgagtcca
    25021 gcttcctgac ctacaggaaa tgacttttga acagaaaaaa aaggaactcc aagggctgtt
    25081 tcaaggccga aataaaaagc tactgactta cttgaaaaaa agacaacaac atttcatcta
    25141 tcagttgaat ttcgaaaaag ccggtatgct tcaaaaagat atcgaattag ttacttattt
    25201 tattagacgg atccaggaac aaaagcagtt tttaagaaca ccatcgctca ccttcagcat
    25261 gccattagca gcagatgaga gtcagaaaaa gcactacctc gtttgttatg gtcaacttgc
    25321 agaaacaatg attacctctg gtgacgtttc tcctgacttc tattatgaaa agaaagaagc
    25381 tcatttatct ttgaaacgtc aattgtcaaa agaagaaatc gatcctgtac aaatcttgat
    25441 cagttaccgc aaaaaattag aaaaagaaca gtttgaaatt gaactgttaa acaaaaaaga
    25501 agctgaaaag caactaaatt agttgcttct cggcttcttt taggcatctt caacttcaaa
    25561 tgtcaattat cctaaaattt attggattaa gtcatagatt tccatcgcta cgatatcgat
    25621 attatcaaat tcgtattgct gatgagtatc tgtttcagtt aattcaaatg tatcggtcgc
    25681 tttatcataa gttactgtac acttctctac gccttctttt tcaaaacggc gaacttgcag
    25741 ttcattatct gctgactcga ccatagcctc cagtcgtttt atgattgcga ctaattgtga
    25801 atgtgtcatc ggaggtcctc cttttcttat ttctgttata ttgtatcaaa agcatagcct
    25861 acttgcattg attttctcta aaaaaactcg ttttttatga ttttttttct ggtatttttc
    25921 cttcaggcca ccaaagtttg atcaaagctt gggttccgtc attctcaaaa cctttatctg
    25981 ccaactcttc atatagtttc aatgcttggg tagttgctgg caatacaaga tccatttttt
    26041 ctgcttcttc taatgcaatc tttaaatctt tgataaaatg tttgacaaaa aaaccaggtg
    26101 tgtaatcttc ttttaaaata cgaggagaat aattgcttaa agaccagtta gctgcacttc
    26161 cacctgaaag cgtctcaatc actttcttta aatcaagtcc gtttttttgt gcatagacaa
    26221 gcatttccgt cattcctgtc atcgtacctg caatcatgat ctgattagcc atttttgtat
    26281 gctgaccttt cccagcagaa ccatgcaatg taaatgtcgt accaaattct ttgaataaag
    26341 gcagtacttg atcataaacg gcttcttctc caccgaccat gatcgtcagt gtaccattct
    26401 ttgctcctaa gtcaccaccg gataccggtg catctaacgc atctgcgcct ttttcttttg
    26461 ctgtttttgc aattttttct gccaggcttg gtgtacttgt agtcaaatca actaaaatat
    26521 gtcctgagat atctgcagaa aaaatccccg actgtccata gtagatttct tctacatctt
    26581 tggggtaacc taccattgta aagagaatat tactttgttc tgctaccgct tttggtgtat
    26641 ctgcccagat agctccttct gttactaaag gatcagcttt tgcttttgtc cgattataga
    26701 cagctacttc gtgtcctgct tctagtagat ggcgtgcgac agcacttccc atgacgcctg
    26761 ttccgataaa accaagtttc attttttcga cctcctaaaa atcaaaaatc cttgcttcta
    26821 tgctagtata cgctagaaac aaggattttt tcataaaaaa tgtttgaatt ttatctttta
    26881 aatgaattta attttatttt gattcgttca atcgagtctt cttcttcttt tcttcgcatc
    26941 tcttcttcat gataaacaac catgtcttga taaaattcga tcatagcttc gccgaaatgt
    27001 gtagatgaaa tatcataaag tttagcttct aaaacttttg gatctttagg aacttcactg
    27061 gaaatataat caataagtgc tggtgcaaag tcttcgtcgg tttcaaaagt tttccctaat
    27121 gaaggatgat cgaacaatcg gttcaaataa gcatttcctt ccacgacaca aggtgttccg
    27181 gctgccatcg cttctgtata agtaagccct tgtgtttctg aagtagaagc actgacaaaa
    27241 taatctgccg ctttataata aagtgctaca tcattgttgt ccacttctcc tgtgaactgc
    27301 acaaattctt ctaactgcag ttctgagatc aattcctcta actcttctac ataaggtcct
    27361 tttcctacga taactaatct ggcgttagga taagcggaga tgacctgagg aaacccatta
    27421 atcaaggctt ggatattttt ctcataagaa atcctgctta aagaaagaat catcaaatgg
    27481 ttttcctgaa gacctagtga ctcccttaat ttgctgatat cctgctgagt gatatcagaa
    27541 cgtttgaatt tttcaatgtc gataccagta ggaatcacgc gaagcggtgc tattacacca
    27601 tagctgcgta atgtatcaat aacacgttca cttggacaaa ctacacctgt cgtatgattt
    27661 gcaaataatc tagacaagta ttttacatgg gattgcctga tcacttttcc tttaccgata
    27721 taatgaaggt agtcttcata catcgtatgg taagtatgga tcagaggtat tttcaacttc
    27781 ttagctacca tcttcccaag tatccctgct ccgaattctg tatgggtatg aataagatct
    27841 agttctagtt ctttggcaac caaataagca taccacatgc ctctaacaac aactcttcga
    27901 tccttgaaag aaataaatgg tacacttggc attcgaatca catctttttc caacttatcc
    27961 gcattaggat cggtcgttgt aaaaatatag acttcatgcc catgtctttc taattcttgt
    28021 tttaatgttt tgatcgatgt agcaactccg ctgacttgcg gaaagtaggt atcggtaaaa
    28081 aagccgattt tcatgttttt cgcctccaaa ctagtccttg acctgattta ctttttttaa
    28141 tttgctagag actttttcat tcagtacact ttcgtataca tttttaagtt cttcaccgat
    28201 tttattgata cttcgctctt ttgctgtttg ataaccggct tgtgtcgtac tcggtagttc
    28261 ttgattggta atctgttgga tcagtcggat aaattcttcg tttgtcttcc ccatatagca
    28321 gttcttgcta tcttctaacc agccattata cactggaata tctcgaacaa gtacgttttg
    28381 tttgcttgct aaagcttcta aaacaacgat cccttctgtc tcttcataag aagggaaaaa
    28441 gaatagatct gcacctgaat acgcaccttc tatgatctct ccacgaatgt aaccaggaaa
    28501 caggacattt tcaggatgat cttcttttac aattttccgg atgttccgag gaatcgagta
    28561 catgggaaca tgaccaaacc aaataaatgt gtattcgggc atcttcttag caatttctac
    28621 gaaatcaatg attcctttac gttcgaaaaa caaaccgaca caaatgatta ctttttgatc
    28681 cggagacagt ttgaaatatt ctctgaactt ttgttctttc attggatcag ggtgatattt
    28741 ctctaagtcg atcccattgg aaatagcttg aatcggcaca cggataccat agctttccaa
    28801 caactgtttt gaataaggtg ttggcgtgat cagatagtcc gctttttggt acaatcctac
    28861 cagatatttt tttacgatag gagaaagctg gttcgatctg ataaaggaat ttcggaaatc
    28921 ttcctctgta gaatgcgcat gatagacaac tttttttcct tctcttctgg ctttattgac
    28981 catattatga ctattgattc cgtatgtatt gatgtgcagg atgtcataat cttctttttc
    29041 atctagtgta taagagatac cgacttccgt cagagcacgt ttttgatgat caagcgcacg
    29101 cccgattcca gattttgcaa gcatcttttc actttcaaaa tataataata ccttcacctt
    29161 acgtccccct tcacttatat agtataacat agcctacaaa ctgtcactca aacttaagcc
    29221 ctatttttgt ctattcttac tgacaaaaac gttttcttaa aaaagaacaa aaaaactggc
    29281 gtagctcttt tacaagccac accagctttt gatacgttgt ttattttaca tattcatgaa
    29341 caagttcaac gacttcttcc atcatatcgc attctttcaa tgcacgatca gcaagttcag
    29401 ccattttcgc tgtgtccaag cgtttcatta aactacgcgt tttaagaata gatgtcgcac
    29461 tcattgagaa ctcatctaga cccataccta ctagcaatgg aacagctgtt tgatctccag
    29521 ccatttctcc acacatacct gcccattttc cttcagcgtg tgctgcatca attacatttt
    29581 tgatcaaacg taaaattgat gggttatatg gttggtacaa gtaagaaacg cgttcgttca
    29641 tacggtctgc tgccattgtg tattgaatca aatcgttcgt acctacagag aagaaatcta
    29701 cttcttttgc aaacttgtct gctaagactg ctgctgctgg aatctcgatc atgatgccga
    29761 cttggatcgt atcagatact tccttgcctt cacttatcaa tttttgtttt tcttcttcaa
    29821 agatcgcttt tgctgcgcgg aattctttga gtgtagctac catagggaac atgatacgta
    29881 aattaccatg aacagatgca cgaagcaatg cacgcatttg tgtacggaac atttcgtcgc
    29941 cttgttcaga taaactgata cgcaatgcac gatatcctaa gaatggattc atttcatgag
    30001 gtaattgcag atatggtagt tctttatctc caccgatgtc cattgtacga acaactacag
    30061 gttttccttc cataccttct aatacagctt tgtaagcttc atattggtca tcttctgttg
    30121 ggaagtctgg agaatccata tacaggaatt cagtacggta cagaccaact gcttctccac
    30181 cattattatg gacaccaact agatcttttg gtgttccgat gtttgcagct aattcaaaat
    30241 gcttgccgtc agctgtgaca gtttctgcat tttttaattt ttcccattct gctttttgtg
    30301 ctgcgtaatc tgcacctgct ttttcaaatt cagctttttg ttcatctgta ggatcgatga
    30361 ttacatcgcc ttcgatcccg ttgacagcca aaatatcgcc ttctttgact ttagcagtaa
    30421 tttcttttgt cccaacgatt gctggaattt ctaaagaacg tgccatgata gcagaatgtg
    30481 aagtacgtcc accaatgtct gttacaaacg cttttacaaa attgcgatct aattgtgctg
    30541 tatcacttgg agtcaagtca tgtgcaacaa cgaccacttc ttcgttgatc attgatggat
    30601 ttggtaaagt aacgcctaat aagtgcgcta aaatacgttt agcaacgtca cgaatatctg
    30661 cagcacgctc ttgcatataa gcattatctt ccattgcttc gaacataccg atatacatat
    30721 ccgttacttc ttttagcgct gattcagcat ttacgctgtt gtctttaata ttttgcttga
    30781 tttgacctac catttctgga tctgaaagaa ccatcaaatg ggcatcaaat acttgcgctt
    30841 ctgcttcacc taagctttgc gctgcttttt cacgaatttg ctgcaattct tcagtagatt
    30901 tagctaatgc agcatccaaa cgagcttctt cagccgcagt atcttctact gttgccttac
    30961 tgaatgttaa atccggttga actagcaggt aagcttttgc aacggctaca ccgtcactag
    31021 cggcaatccc ttttagcatt tcaaccatta ttcagataag ccttctttct tcattgtttc
    31081 aacgattgct gccattgcat cagcttcgtc agcaccttct gcagtaatag taacatcaga
    31141 accttgacct acacctaaag acataacgcc catgattgat ttcaagttta ctgatttacc
    31201 tttatactct aagtttacat cagagttaaa tttgcttgct gtttgtacta atagtgtagc
    31261 tggacgagcg tggatcccag tttctgctac tacgtgaaat tctttctttt ccatattaat
    31321 cggtctcctt taagtgagtg ttgtttttat gtgagggttt tcttttttag taattcagag
    31381 aatcctaaca aatgccaccc tttcatctgt aaagattaac attttttttc gttagataca
    31441 acagttttca ttcaatttca gataaaagta ttcaaattat tccggattct ttttcatcct
    31501 tttcttcaca ttttataaca aacgtgttta tttccttttt cttgtcgctt tctcttctcc
    31561 tgacgtttat cattctttcc tttgaccctc tttgttttca tatgaaacga attacttgct
    31621 tcccttttta tttttagtat aataagagtc aaaggtcagg aatggtcaat agagatttca
    31681 ccttttctac ctcataaatc tcttaaaaaa ctaggggtta ttcttttacc tcatgaaaaa
    31741 cgagatgtaa aatatggatg tacccatttt tgtgaaagga cgtgaatgat tcatgctttg
    31801 tcaaaactgc ggcaagaatg aggcaacgat tcacttgtat gccactgtca atggtcagcg
    31861 gacacaactc gattactgtc agagctgtta tcaaaaaatc aaaaatcaac aaaatggagg
    31921 tctgactaat atggcccaaa atgatccatt tggatttggc agtttggacg atcttttccg
    31981 ttccatgtct cgccaaatgc aacagcaagg aaattatgag caaacaccac caacacaatt
    32041 tggcggaaac aacaacttca atggtggtca gccacctcaa ggcaatacag aaggtttatt
    32101 gggagaatac ggaatcaata tcacagaaca agcacgacaa ggtgatatcg atcctgtgat
    32161 cggacgcgat gacgaaatca aacgagtcat tgaaatttta aatcgccgaa ccaagaacaa
    32221 tcctgtcttg attggagaac caggtgttgg taaaacagca gttgttgaag gtttagcaca
    32281 aaaaatcgta gatggtgatg taccgcaaaa attaatggac aaagaagtca ttcgtttaga
    32341 tgtcgtatct ttagtccaag gtactggtat acgaggacaa tttgaagaac gtatgcaaaa
    32401 attgattgaa gagatccgtc aagcagaaaa tgtgatccta ttcatagatg aagttcacga
    32461 aatcgtcggt gctggttctg ctggtgatgg aaatatggat gctggtaata ttttaaaacc
    32521 agctttagct cgaggagaat tgcaaatggt tggtgctact accttaaatg agtaccgcat
    32581 catcgaaaaa gacgctgctt tagaacgtcg tatgcaacct gtacgggtag atgaaccaac
    32641 tgtcgaagaa acgatcagta ttttgaaagg tttgcaaaaa cgttatgaag actatcatca
    32701 tgtaaaatat actgatgagg ccatcgaagc agccgcaact ttatccaatc gttacgtcca
    32761 agatcgcttc ttgccggata aagccatcga tttgctagat gaaacaggtt ctaagaaaaa
    32821 cttgacgatc caaatcgttg atcctaaaac aatcgagaaa aaactgcaag aagcagaaga
    32881 acaaaaagtt ttagcttctc gagaagaaga tttcgaaaaa gcagcttatt atcgcgatca
    32941 gatcaataaa cttcaaaaaa tgaaagaacg tcagctcact gaagaggaaa cacctgtgat
    33001 taccgaaaaa gatatggaaa aaatcgttga acaacggaca ggtattccag tgggtgaatt
    33061 aaaagaaaaa gaacagacac aactgaaaaa cttagcagat gacttgaaag ctcatgtcat
    33121 cggacaagat aacgctgtag atcgagtagc gaaagcgatt cgccgaaacc gtgttggatt
    33181 aaacaaacag aatcgtccaa tcggctcctt cttatttgtt ggaccaactg gtgtaggtaa
    33241 aacagagctt gcgaaacaac ttgcctacga actattcggt tcacaagatt caatgattcg
    33301 tttcgatatg tctgaatata tggaaaaaca tagtgtctct aaattgattg gttctcctcc
    33361 aggttatgtc ggatacgaag aagctggtca attaacagaa aaagtacgga gaaatcctta
    33421 cagtcttgtc ttgttagatg aagtagaaaa agctcatcca gatgttttgc atatgttctt
    33481 gcaaatctta gatgatggtc gattgacaga tgcacaagga agaacggtca gctttaaaga
    33541 tacgatcatc attatgacaa gtaatgccgg aactggtaaa gtagaagcaa acgttggttt
    33601 tggtgcggca cgcgaaggtg ttactcgttc tgtattgaac caattaaaca actactttac
    33661 accagaattt ctgaaccgtt ttgacgggat catcgaattc agtgcattat caaaagaaaa
    33721 cttgatgaca atcgtcacac taatgctaga cgatgtcaac caaatgctgg cagcacagca
    33781 acttcacatc gaagttccta cgaatgtcaa agaaaaatta gttgacttag gctatgatcc
    33841 atctatgggt gctcgtcctc ttcgacgcac gatccaagaa caaatcgaag atggtatcgc
    33901 tgaattttat cttgatcacc cttctatcca tgagttgaaa gcaaaactgg ataaagatgg
    33961 aaaaatcatc gttacttcta aaccagaacg tttggctaaa gaatcagccg aagaaacggc
    34021 tgaataaatc cagttttata gcgtgagacg gtatttcttt gagaaatgcc gtctcattct
    34081 tttttcagaa aagtcaaaat actgttcatt ttataaaaaa gaaattataa taagagaaac
    34141 aagcaattaa aaatacataa aagaggtgag cgccatgaaa ttggtaaatg taacaaacag
    34201 ccattcccgt cttgtattaa accagcttga aaacactgat gcccatctag tcaaggtcta
    34261 cacagccgga aataccacta ttgtctacac tgaagcccct gaacataatg aaattctgct
    34321 gatcaatgac aaacgtaaaa tccagccgaa agaaatcgaa gatgctaaaa attatttctt
    34381 agataaaatc aaagacgccg tttaccacga ggatgaaatc aaagtaatcg aattggcagg
    34441 ccttgttgaa atctcgattc caaaacatga attaggcgct acattagccg tgtaaacaaa
    34501 ttttgaacat aataattaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct
    34561 ctaaacacgt ataaacggcg aaagcagaag caactccttc ggaaataagc tgaaattcac
    34621 gaaaattgct tttcaaattt ttgtgaattc cagcttattt cttggagtta aacgcttctg
    34681 tctcagcctc tttttctttc tagctttttg atttttctct tttcttttgt acttttctct
    34741 tttcattttc agttctacgc gtgtctttat ttttaacttt ttcctcttta tggatgattg
    34801 atcgtacttt ttgtgcaatt tgctcgtttt tgtcccagtc ttttacatct aataatcgac
    34861 ataatcgtaa catctcttct tttttctgtt tttttctttc acgtctttgc cattctgttt
    34921 ccatgtgtca cactctcctt tctttaatca tatgtacgca aaataatttt tatatttttt
    34981 tgattagaca tttctatgat tttaatatag taaaaagagc cgtcacggaa aatccgtcac
    35041 ggctctaaac aaaatatgag aggctgtttt tgtttggcta ttcttattac ttgatgcagg
    35101 gcagcttgtg tcaagacttc tttacatcaa actttttaat tttacattgg gatatttatc
    35161 cgcaaaccag cgttctgcaa attggttctc gaataagaac aacggttggt cgaaacggtc
    35221 acgagccaag atattgcgac ttgaactcat cttctcatcc aaatcttctg gatcgatcca
    35281 gcgagcgatt ttgtgtccca ttggagacat gattacttcg gcgttatact catttaacat
    35341 acgatattgg aatacttcga attgtagctg accaacagct ccaatgatat attcttccgt
    35401 tagatatgtt ttataaagct gaatcgctcc ttcttgaact aattgataga ttcctttgtg
    35461 gaaggatttt tgtttcatga cattttttgc agtcactttc ataaacagct ctggagtaaa
    35521 tgaagggagt tcttcataag caacttttag ttttccttcg aacaatgtat ccccaatctg
    35581 ataattgcct gtatcatata caccgatgat atcgcctgct actgcttttt cgacgttttc
    35641 tctcgaatct gccataaatt gtgtgacatt gcttaatttc agttttttat ttgtacgttc
    35701 caaccagaca tccattcctc gttcgaatgt tccagaacag attcggacaa aagcgattcg
    35761 gtcacgatgg gctggattca tatttgcttg gatcttgaat acgaaacctg aaaattcttc
    35821 ctcataagga cttaccatct gatcatcttg tgttttgtgt ccataaggag ctggtgccaa
    35881 ttcaacgaaa gtctctaaaa aagtctgtac accgaagtta gtcaatgcag aaccaaaaaa
    35941 tactggtgtc tgatcgccac gagcaatttt ttcttgatta aatgcatctc cagcctcttt
    36001 gattagttct acttcttcta agacttgttc atataaggaa ttttcagtta gaggatgatt
    36061 ttcgggaagc agtccatctt catccaattc tactaatcgt tcatcctgat aattttccgg
    36121 acgataaaac tctacacgat tatggtagat atcataaaga ccttctagcc ctttacccat
    36181 accgattggc caattcatcg gataagattc gatatctaat agctcttcta attcttctaa
    36241 caattccaat ggttcacgac catcacgatc tagtttgttg ataaaagtaa atatcgggat
    36301 gccacgtttt tttacaactt ggaataattt ctttgtctgt gcttcgatcc cttttgcact
    36361 atcgattacc atgaccgcac tatccacggc catcaaagta cgataagtat cttcagaaaa
    36421 atcttcatgt cctggtgtat ccaagatatt tactcgtttc ccttgataat caaactgcat
    36481 aacagaacta gtaacagaaa tcccacgttg tttctcgatt tccatccagt ctgatttggc
    36541 aaaattacct gtttttttgc cttttacggt cccggcttga cggatagccc caccaaacaa
    36601 tagtaattgt tctgtaatcg ttgttttccc agcatccgga tgggaaatga tcgcaaaagt
    36661 tctgcgattg tccacttgtt gctttaattt tggattattc ataacctaac tccatttctt
    36721 ccattcaatt atttatattt tctctaggca cagattgtcc gatctcttaa agaaagacaa
    36781 tttcatatag ggctgtgaca aaagccgtgt agcagtctct ttttccgagt aaacggcgtt
    36841 ctagagacag cctatcagca ataagcccac ccaagccaaa aatacgaaaa gctgtttttg
    36901 cttggctgct cttattactt aatgcaggat agctttttca caacctttgt caactactac
    36961 aactgaatca gtatagcatg gattcagcga atgaaaaagc caccaaacca taagagtcaa
    37021 atattttttt gtcagctgac taaaagaaaa gacgtgttgc ttgtttattc aagcaacacg
    37081 tctttcataa ccaagtttcc aattatcttc ttggctcgtc atcttcgaat tcttttctga
    37141 agtatcttcg ttcttcttca ggttccgctt ctgtttcttc cggatcatga aaaatgacac
    37201 ggattttaag gattcgagaa ccttccattt cttcagaaac cagcgtaata ttatcgacat
    37261 caaacgataa cttttcgcct tcatccggaa tcatgcctaa tgctgtaatc aaataaccag
    37321 ccatcgtatc tacatcactc atatgcagat cactgtcaaa agcttcattg aactcatcaa
    37381 tcagcatacg tccttggatg atatattcgt gttcatcgat tttttcataa agattctcaa
    37441 cttcatctga ttcatcatcg atttctccga cgatttcttc taaaaggtct tctagtgttg
    37501 ctaacccaac gacgccgcca tattcatcta ataaaatagc catctgattc tgcgtctttt
    37561 tcatttcata taacagatca tcaataaaga ccgtttcagg aacgaataaa ggctcctgca
    37621 tgattttctt gatatctaaa ttatcaaagc cgaatttatg ggcagctttt agtaaattct
    37681 ttgtatgaag gattccgact actttatctt tgtcttcgtt ataaacaggg attcttgaat
    37741 agttttcgga taaaacttca ttcacatttt cttccacagt gtcgttgata tcaatcataa
    37801 atgcatccgt tcgtgggacc atgacttctc gggcaacttt cgtatcaaga gaaaaaaccc
    37861 cttggagcat ttctaattct tcattattca atacgccttc gttttcaagc atataacgca
    37921 tttcatctct ggtcattttt gaatcttcat catcaaaagt catcggcgtg atacgcgcca
    37981 ataaacttgt ggaagcagaa agcagccaga cgaagggctt agctactaca ccaatcaagc
    38041 gtatcagccc tgaagtgaac tttgcgactt cttctgattt atttaaagca atacgtttag
    38101 ggtacaattc tccaaaaaca atcgatacat aggtcaaaat agccagcaca atgatatttg
    38161 caatattttt tgccgctgtg ccgccaccta ataccggagc taaccgttcc gataaagtat
    38221 tagctagtga agcaccagac aaaatgttga ccaaagtgat tcctacttgg attgtcgata
    38281 ggaaattatt tggattctgc aatattttta aaagcttttg agatttcaca tctccttcat
    38341 cagctttttg ctcgattcga ttcttattga tcgaaacaac agcaatttcg gaagctgcta
    38401 aaaaagcatt gatcaatgtc aaaacgatca ataataaaat ctgcgctaac agcgactgac
    38461 tctcagggtc agcattcata atcgcattct ctccttataa aattaatttt tagtttacga
    38521 tagaaaaaaa cgtggcacta tagccacgtt aaaatggtat cacaaagcaa ttttctttgc
    38581 aataaaaaca agtgtactaa aactacctac gaggtcgtag caattttctt cttgttttca
    38641 ttttgcttgt cttctttgac gattttgatt atataggaaa tgatcgtctt gcagattgcg
    38701 taaaaaggaa cacctaagaa gataccaagc aatccggcaa tatttccagc tactagaaga
    38761 acgataatga tcgttaatgg atggattttc agtgatttcc caattacatt aggataaatg
    38821 atattcccat ccaactgttg gacgattagc acaaccacac aacaaagtaa tgcttttacc
    38881 ggatcattga agactgttac tagaaatgca ggtgctagtc ctagataagg tcctaaatat
    38941 ggaattaggt ttgtcaatcc cgcaatgacc ccaaataaga aagcataatc cacaccaatt
    39001 accatatatc ctaaaaatgt gaaggtacca acgaataaac attcgattgc ttgtccgcta
    39061 atgtaattag ccaatgtttt attcagttgc cccaataact ccacaatttg gtttcttctt
    39121 ttttctggga aaaactgttg gatgtttggc actagttttt ctccgtcttt caacatatag
    39181 aacaagatga atggtgctgt aatgattact acggttgccg aagcgatcgt tccaacgatc
    39241 gaacctaaac tattggatac tccactaagg aattgctgaa tgattgtccc gtaagaaatg
    39301 tctaattgct caaaatattt attgatatct acttccttga acaaaggcaa ttcggctacc
    39361 tcttttaacc agctttctac ctgtttgatg aaatcaggca tattagatgc caatgaggaa
    39421 atttgctgta ctagacttgg gatgacacta agtaaaatcc aaataattgc tgcaactaaa
    39481 aggagcagca caattgcgac agcccatatt cttttgattt ttgctttcat caacagcttg
    39541 acaataggat tcaataaata gtaaagaaag cctgcaatca gtacaggtgc aaataacgtg
    39601 gaaaaaaatg tcccgatcgg ttcgaaaata aagtttattt ctgatgaaat catgatcaat
    39661 gcagctatga tcaataattc aagcgaccaa aacattagtt tagactgtct aagtttttca
    39721 aacaatagat ttcctccttt ctttcttact agtatatatt atattcgtta aaaattcttt
    39781 tattcttttt ttatttttga aaacttgcca tactttttat ttgttttatt ttccagtata
    39841 ctatacgaaa ggaaggtggc tagaccatga aagttgtaca aacaaaagat acaatgagca
    39901 atatttactt agatgctgta cggatcaggc atcaagtttt tgtagtcgaa cagggtgtgc
    39961 ctttgtctcg agaaatagac aaagatgaag cccattgtat ccacttcgtc ctgtactcag
    40021 ataaaaaaga accgcaagga actgtacgtc ttttgccttt agaaaacgga aaaatgaaat
    40081 tacagcggat ggcgattctt tctgaataca gacaccaagg gttaggaaaa atattgattg
    40141 aagaagcaga aaactttgct aagaatcaag gctataatac gattttatta ggggcacagt
    40201 ccacagctga aactttttac gaaaaactag gatatacagc ttacggcgat ccttttgaag
    40261 atgctggcat gcctcatatt tatatgaaaa agactttata aaaatttatt tcgaaaaaag
    40321 caaaaaacag caagcttttg agaaaaatct ctcactggct tactgttctt ttttgtgttt
    40381 acttacgcga caattgcttg taacggttat accaaatatc aatatagcct tccgagaacg
    40441 ggccatctcc attattgatc cagtcaacca gaatcttcac attttctttt aggatgaagt
    40501 caatatcgtt cgggtaattc atcattttgc tgtgcatctc atattcatcg acatccaata
    40561 gtcgtttctc gccgtcagga aataccttga tatccaagtc atagtcgata tatttcaagg
    40621 cctcatcgtc cagcaaaaaa ggtgaagcta gattacaata ataggaaacc cccttttctc
    40681 tgatcattgc tattacattg aaccagtatt ttttatgaaa ataaacaatc gctggttcgc
    40741 gcgttaccca tcggcgtcca tcagattcag tgactaatgt gtgatcattc acgccgatca
    40801 tagagtgttc gcttgttttt aataccatgg tatctcgcca cgttcgatgc aatttgccgt
    40861 cgtgcttgta actttggatc gtcacaaact ctccttcttt tggaactccc atagcaaccc
    40921 ttccttaagc agcattttgt gctttgtgtt tgggtgttca ttacaccgac atcataatta
    40981 ttatatcaat aaaaatgagc tttgcctaga aaggattcct attgtttcga tttttctcta
    41041 actgatctac cagtttcatt tggaccttag gaaaaacgac cgaatcaaat gcatcaggct
    41101 tcaaccactt cgaagttttg ttctcggtaa attcttgttc tgctccctcg gttgcccgtc
    41161 cgtaaaaaag gagaacatgc catttcagat gactaaaaat atgagtaact tctcctaaat
    41221 gtcgtgtctg ccaaacaaag agttcctgct tttcaaatgg gagattttgc tcttcttctg
    41281 ctactaggtc atcaaacaga tcgatttctg gctttgtttc ccattctttt ttcaatcgct
    41341 catactcctc ttgtgtcact tccatcattg gaaatgtcca catattcgcc agcaattttt
    41401 ggctatctct ttcttcaaaa taatacgctc cagaatgatt ttgaagagct gcactgatat
    41461 aataaacgtc ttttggcttt gctttttttg tttttacagg aaaactcgtt tggattcctc
    41521 gtttgttagc taaacaaaag gcttggatcg gacaagtctc acactttgga gaagttggtg
    41581 tacagatagc tgaacctaga tccatcattg cttggttgaa ttcacctgga tgcttttcat
    41641 caatgatttt ccgcatcgct tcatcaaaga ttttcctgct agaagctttt gcgatgtctg
    41701 cttcaatgca aaacaatctg ctgactactc gcatcacgtt gccgtcaact gcaggttctg
    41761 gaagtccaaa tgcgatactt gcaatcgcgc ctgtcgtata tggtcctatt cccttcaatg
    41821 agctaatttc ttcaggcgtt tgcggcattt ccccatcaaa ttctgacatg atctgtttag
    41881 cagcagcttg gatgttccgg gctcttgagt aataaccaag gccctcccat gcttttaaaa
    41941 gcttttcttc tggagcattt gctagctctt caattgtagg aaaccattcc atgaaacgat
    42001 aaaaataatc gatcactgtg tctactctgg tttgctgaag catgatctca gagatccaga
    42061 tacgataagg atcacgatta tagcgccaag gcaggtttct tttttcttgt tcataccatt
    42121 gaatgaactg atcttgaaat tcttttgttt ctttatctgt ccatttttcc cattctttat
    42181 tcactttcct cttccttttc cgtaatgaat cgctggatca tatccaaatc aaatcctttt
    42241 tgatataagc tttgctttac ttttagattt ctttttttag gttcaaacct taaatttctt
    42301 cgccatagtt tatctccttg tttgactaaa taatcatatt ctatttcttg atctgcttct
    42361 tgcggaagat cagctatcgc ttgttggatc acttcttgag aaaagccttt cgtcatcaat
    42421 gtttgttgga tttttctcaa taattctttt tggctttttc cgtgattttt tccaaacgct
    42481 ttttcggctg tctgatgtgc attttgaact tggtcttcaa atgtatattg gctgagcgct
    42541 tgttcaatga tttcaggttt caaacctttt tgctgcatct gctgcgctaa tttctttggt
    42601 cctttgtcac ttaagcgcat attcgtgcgc acataacttt ccccatagac caaatcatcg
    42661 acaaggtcca attcttttaa gcgggctacg attttatttc gatcttcttg aaggatttcc
    42721 ttttctttta agtatgttcg gatttctttt tccgatcgca actgataact taagtaattc
    42781 attgctaggt gaaaaccgaa atcagctccg ctactcttct tgatctcttg gatagtttct
    42841 tcgtctaatt cccgtccttt taataatcga tagcgtacta atacatcttc agatacttgt
    42901 aaagcttctc cttcagataa atctacgcga tagaaagggc ctttgccttt actgattctc
    42961 gtaacggtta acataaacat cctcctcgaa catatattct ctatcatacc acagaaaatc
    43021 cccgtaatca ggtattatat gttagaataa accacagaaa aaagaaaaag ggagatactt
    43081 atggcagaaa caattgtcaa aactggacaa acggttcctt tgaaaatcaa gcgtttaggc
    43141 ataaatggtg aaggaatcgg ttatttcaaa cggttgatca tatttgttcc atatgcacta
    43201 ccaaaagaag aagtactagt gaaaatcacg aaagcaactc ctcgctatgc agaaggagaa
    43261 ttaataaaag tcaaaaaaac aagcaaagat cgcgtagtgg caccatgtcc tgtttactat
    43321 gaatgcggtg gctgtcaatt acaacactta gcttatcaag ctcaattgga ttttaaaaag
    43381 gatctgcttt tgcaagcatt ggaaaaattc aaaccagcag gctttcgatc ttatcaactt
    43441 ttgccgacga tcgggatgga tgagccttgg cattatagaa acaaagcaca atttcagtta
    43501 cgaaaaaata agcagactca aaaaattgaa gctggtttat acgaagcaaa ctctcatcag
    43561 ttagtcccta taacagactg cttggttcaa gaacctcgaa cacaaaaagt aatgaatact
    43621 gttgttcaac tattgaataa atttgatgca cccatctatg atgaacggac aaacagtgga
    43681 atcttccgca caatcatggt tagaatcggt gttaaaactg gggagttaca agttgttttt
    43741 attactcgca gtaaaaaatt cccgcaaaaa aacgcaatga tccgtgagat caatgaacga
    43801 ctgcccgaag ttgtttcaat catgcaaaat gtccaggcac aaaaaacgtc tctcgtgatg
    43861 ggggatgaaa cgatccactt atggggaaaa gaagccattg aagaacaaat caatgaagtg
    43921 actttcgatc tttctcctcg tgccttcttt caactcaatc ctcagcagac cgaattgctt
    43981 tatggcgaag gaatcaaagc attagatgtc cagcctaatg aaacgatcgt ggatgcttat
    44041 tgcggagttg ggacgatcgg cttaagtgta gcaaaacaag ccaaagaagt acggggaatg
    44101 gataccgttc ctcaagcaat cgctgatgca aaaaaaaatg cggaaagatt aggatatcac
    44161 aacactcgat atgaagtcgg gacagcagag caagttctgc ctaaatggtt gaatgaaggt
    44221 tttcagcctg atggtatcat cgtagatcca ccacgtacgg gtttggataa cgcattgatc
    44281 caatcattat tgaaataccc tccaaaaaaa cttgtttata tctcctgtaa tgtttctaca
    44341 cttgccagag atctggttaa tttaagtaaa aagttcaaga ttgaatattt acagtccgtc
    44401 gacatgtttc ctcagactgc acgttgtgaa gttgtcgtga agatgacgag actcgctgac
    44461 taaatgaaag aggttgtgaa aaagtctgcc ctgtatcaag taataagaac agccaaacaa
    44521 aaatagctct tcatgtttta tgaatactgt acttgtgacc gaagagttaa caggaggaca
    44581 ctatttattt aaaaaaaggg ttgtgacata gtttttgtca cagccctttt tgattattat
    44641 tggatattca cgtctatcac ttgataaaat gcatttgtcg tatcgctgat attccatact
    44701 gctaaaatca cattatatcc ttttcgatcc tgcggaagtg tgatcgtttg gttgactgtt
    44761 tttggtggaa cagttgcttt gtcgtctatt tttgtgatca attcaaaatc actaaatttc
    44821 aaaggttgat taggattcca agttggtttg gtaatgtagt aatcccaagt acttgtccga
    44881 tgttgtgctg ttaaattcca agtaatattt aatgttcctg gattaaccat gtttttatgc
    44941 catctgttag atgtctgttc atctaaaggc tcaaagccgc tgactcctgc actagcaatt
    45001 tttccatcaa tgaatgtatt tttggtagct tcgatacttt gcggttccca ttgtgctctt
    45061 ccgacatttt gatttaagtt tcctgctgct gatgttccta ggtatgcacg gcttcctgga
    45121 gaagtaatat aaccatgcgc aaaacctgga atgctaaaac cgaacaaccc taaactaact
    45181 aacccaataa acaataacgt actaatcttt ttcatgtaga aacctccttc atttgataac
    45241 cacattgtaa acgctttatt gtattaacac aaacattatg cttttataat tttatgttga
    45301 agtaaaaaag gtgaaaaaag taagatgcag attataacag aagtagacga gaaaagtaca
    45361 aatagaaaac atgagaatca aatcatatga tctttttcaa aaacatcatt catataaaca
    45421 aatgttcaac tttttaataa caacaattat caattttttt cttacttcac aaactaaata
    45481 caggtcttgc tgtgagcctt catggtaaac taatattata gaaaggagtt agtaaaatga
    45541 agatgataaa agatattcgt ttttgggttt gtgttatagg aattgtcata ttaggctttt
    45601 tatcagggtt gcttagcgga aatcccggaa aatattacta ttctttgcaa cttccaccat
    45661 ttgcaccacc tagctggata tttgggccga tgtggacctt actgtatata ttgatgggta
    45721 tttctcttta tttgttactt aatcacaaca acaaaaaaca gcgaaacaat cttgtcggtc
    45781 tttttgtgat tcagttcatt tttaatttta tatggtctgc tctatttttt aatttaagaa
    45841 atattttcat tgcagcaatc gatattacac ttttagttat tttcttgtca gtgcttatgt
    45901 atcagttgtg gctgcatcat cgcctggcaa tgtggctcat gattccttat tatttatggg
    45961 tactattcgc aactctattg aattattcaa tttatttttt aaactaagcg ctaaaaagag
    46021 acgtcctgta atttaacaca tagaaaaagt gccacctaag ttagattttt tgtctaattt
    46081 aggtggcact ctttattaac caaactattt ttttctagta cccacttgtt gttccatact
    46141 cattattctg gtcataacca taaccatttt gttcctgtcc agcgtaagga tcataacttt
    46201 gagtatcttg acttggtgta tagtactgac ttgtatcttc tgtttgctga taataggtat
    46261 tcggatcttg gtactgatca tatgtgtttt ctgaatagga agaataatcg gtgtaccctt
    46321 cactattcga tccatcaccg tttgtcgaat cgccatcttc cgaatcatca aagaacatca
    46381 ttgaagcatt ctcatttttc aaattaggta atgtatcgct tgtttttata tttaattgtt
    46441 tcttcagttc attttggatc gaaagaagat cattttttcc taaaatttga tagtagatat
    46501 cattgatcat ttgtccttcg ccttgcaact ggtcttgttt gattgtttca aacgccgggg
    46561 tgtagttcgt cgctacatca agcatgtcat cccaatctaa gtccgtcgtc acattgttct
    46621 caactgcttt taaaattttt ctataattgc ttacgccatc taaacttaaa actttattga
    46681 cgattttcgt cactacttcc cgctgacgac gttgtcgacc gatatcgcct tctggatctt
    46741 cgtgtcgcat tcgagaatag gctaaacctt tttctccatt caatgtttgt tcacctactg
    46801 gtacatggac accatccaaa gtaaagtcaa ttttattatt cactttgatg ccaccgaccg
    46861 cattgatcaa atcttccatg ccatccaaat tgatcgttac ataatgatca ataggaatat
    46921 cgagcagttg ctcaattgaa tccatggcca tttcgacacc accaaatgcg taggcatgat
    46981 ttaatttatc taccgttcca taacctacga tattcgtata aatatctcgg tccaaactga
    47041 tgatcgttga ttttttttgt ttcggattaa ctgttactac catcatcgta tcagaacgtc
    47101 cttgttccgt tcttcctaat ccaccggtat ctaaacctaa tagcaaaacc gaaaaaggtt
    47161 ctttgtcatc aatgcttact ctctcagaac gtttggagga tattcgatta gagtttttag
    47221 aaattttgtt tactgtttgg ctcgcttctc ccataaatct gattccgtat gctgataatc
    47281 cggcaatcag caaaacgaat acccctaaca aggttaatag aactttttgc catcgcttca
    47341 taatacacct ctgtttcaca ttttctaaaa tattgtctca tataactgtt caatcagcaa
    47401 attcactttt taatcataag aaaactttaa aaaacatttt tgtgtaacga ttattatttt
    47461 ttaaaatttc tcaaaattct taactatcat accataccgt gaaaaagatc gaaagaccga
    47521 atacacgcag ttcgcaatcg ttttatcttt ttttatgtat tttttccaga aaaagcgaac
    47581 aacaaggtat tttccaaata atcgtgcagt aaaatgatcg cacatacctt tcccatcttt
    47641 ttaacagtct ttgcctaccg ttcagattat cattcgattt cacgacaatt tcttcctatg
    47701 actggtcctt ttgttaaacc catcttctat tcgttttatt tccagctcac tgcatggctc
    47761 ttaaaatgac tcgaactagt gattgcatta ccatcatctt ttaatggata gatatgctcc
    47821 tcttcaaagt aaaacgattt tcttttaaag taatagaatt gacatggtaa tgagtatgta
    47881 tactagtggt ttcacaaatg gtcttttatt caacatccaa aaactgaaat ttctttaaaa
    47941 tccattacta acgaagaaaa tgttccttgc ttgataatta gttaggacat gtcaagtgaa
    48001 caaatgcatt tacttagcca aaaaatctaa aaacttcata aatagacaaa aagacacgac
    48061 tctctaagaa gtcgtgtctt tattcaacaa attattataa tttagtcact tcagcagctt
    48121 gaggtccgcg tgcaccttca acaatcgtga attctacttc ttgaccttct tctaggctct
    48181 tgaagccgtc tccttgaatt gctgagaaat gaacaaatac gtcatctccg ccgtctactg
    48241 taataaaccc aaatcctttt tcattgttga accatttaac cgttccgtgt tccataaatg
    48301 tatatcctcc aaaaaagttc ttgcaagtaa ccttgcaaga acattatacc caatttagaa
    48361 aacgctagca agctttcgct cttttatttt ccaaattatt tttaagactg atatgacgga
    48421 ggaaatggtt attttgctgc ttcgaaacgt ttgtttactt catcccaatt aataacattc
    48481 cagaatgctg caatataatc tggtcggaca tttttatatt tcaaataata agcatgttcc
    48541 caaacgtcca aacctagaat tggtgtcttt ccttccatca atggagaatc ttgatttgca
    48601 gtagaggtaa tagctaattt tccattttcc attacaagcc aagcccatcc agaaccaaat
    48661 cgtccagcgg ctgctttttt gaattcttct ttaaaagaag aaaaatcacc aaaagcttca
    48721 ttaatcgctt cttttatttc tcctgtaggt tcgccaccag catttggtgc catgatttcc
    48781 cagaaaaatg aatggttagc atgtccgcca ccattgttac gtacagctgt cttgatatct
    48841 gttggaatag cgtccatatc agataataat tcttctattg ttttttcgcc taattctggg
    48901 tatttctcaa ttgctgaatt taaattcgtc acataagtat tgtgatgctt atcatgatgc
    48961 agatgcatcg tttcttcgtc aatataaggt tccaatgcgt catatgcata aggtagatct
    49021 ggtaatgtgt aagtcataaa aaaattcctc ctcaatgttt tcttaataat gtctacatta
    49081 caaagagtaa caaagagaag gaaattcttc aattgttatg cctagtcgtc tttttcactt
    49141 tgacctactt cttcttcaaa aacctcagtt tctttaaaaa taaacaactt gctgaaaata
    49201 tagttcgcaa ggataacaat aatttgagtg atgattttcg ccacatactc attgctgttc
    49261 ataacattga tcaacaatac cattgccccc atgtccaatc cgtaagaaag gatacggtag
    49321 aagaagaact taccgcattc aataagtgca tgtgtaaaat tcggtgattt tgaatggaat
    49381 acccaaagtt tgttcgttac aaaagcaaac aatacagaac aaaaccacga aatagaattg
    49441 gataaggcca tacttaaatc aaaatattgg cgtgcgagag caaaactaac aaaatttaca
    49501 atcgtagcca aaccaccaaa aaagagatag actagtatct cccaatatcc ttttgcttct
    49561 aaatatcctt ttaactgtcg atactgcttc atgagccaac ctaccttatt aaaaattctt
    49621 atttatcata ctctatattt caataacttt catctttatt taaaaaaatt aatttttttt
    49681 gatcctttgc ctttgtctct gcttggatcg tcacatgtgt aataccatat tttaatttta
    49741 ataaagaaat tatacgagga tatatctttt caatctcgct tagtagctga tcttcaaaat
    49801 caatatgtcc gtcgaaaata attatctttt cgctatactg ccaaatatgg acatgatgaa
    49861 catcctttac cccatcgatt gcttcaattt cttgttccat tttttcatag tcgatagcag
    49921 gtgcactttg tatcaaaata gcggcagctt ttttgatcac cattatcgct tctatcaata
    49981 tatatatcga aatgatcagt gtaataactg gatcgatcca gtagatatcg aaaaaacgga
    50041 tcaaaattgc tccgataatc acacttaccg aagacagtgt atcacttaac aaatgcaaat
    50101 aactagattt tatattcaaa ctttcatctg cttcttgtcg taataataat actgagaaca
    50161 aattcgcgag caatccaata actgctactg ttagcatcaa atgactattt atcttttctg
    50221 gtgaagtgaa ccgcttgaat gcttcaacgg ttaaaaacaa ggataatatg atcaatatga
    50281 atgagttgat gaaagcactc aatatttcta aacgctggta gccatacgta cgttttttat
    50341 ttgcttcttt tcgggccatt ttttgtgccc cgtaagaaaa aataattgcc aatgtatcac
    50401 taaggttatg gaaagcatct gaaacaagag acaaactccc tgacataatc cctccaataa
    50461 attctgataa agtgatcacc gcattcaaaa ccactactcc aaatagtttt tttgatgatc
    50521 tctgtggctg tgtaggcact attccttcct ccattttatt tatattggat agtctttaga
    50581 caagaataac atttttttga tatttcacca atcattcagc tgtttcctta aagcacttgt
    50641 atttcacttg atacttcgct agaattgcaa gtgatgacac tactagatga ggagtactta
    50701 tgacaacaaa acaattaatt atcagttcct ttatacgatt caaagaccta aaggaggcga
    50761 gaaatgtccc attttggaaa gccattgtct atcttttagt tttgagtata attatggctt
    50821 tgccaatctc ttttcaagtt tttcaagtct taaacaacat tcaattggat gggcaaaaga
    50881 ttgctactcg cattcctgat tttacaatcc aaaacgggca gcttcaaacc gaagaaaaag
    50941 aaggattcat ttaccaaaca aactccatta tcttcacatt tgatccagag ggaaaacgaa
    51001 cagaacagga catctctact gatttgatgg ggaattttgt tagtgtcggg atgttaaaaa
    51061 acaaacttat catagctctt cctaatacag gcacgacttc tgctttgttg aacaataacc
    51121 aattagaact tccctacacc aatgaatctt taaaaaactt aacaggtaag cagctccgtt
    51181 cttttttaag tgaagcatct ataccacttt ggataaaagt cctgacattt atattttcta
    51241 tttatcctag ttttctgaat ctgctgatca ctttgctatt taccaacatt gctgcttttc
    51301 tctatgcacg ctttcgacta acaaaagcta cttttcttga ttgtttaaaa acattgatct
    51361 attcaatttc attgcctact ataattgcaa caatcttgat ggtctttctt ccttcttttg
    51421 acactagcgc cttcattgct tttgcaggaa tctttatttt tgctcaagct gtcaaaggat
    51481 gggcaaaaat atcgatcaat taagaaataa agacaactcg ttatttctac ttcaatagac
    51541 ccttttagag gttgtgacat ttttttgtca cagccccttt tttatttgaa aaatatttct
    51601 ttctcaaaaa acaagcaagg cgcttcaaag ttcttcttgt atgcgctaca cttagagtaa
    51661 agaaaggcgg gaaattaact atgtcagaaa gaatcattta tgcagatcgt ccatttcgtg
    51721 atgaatttat cgaagaaatc catactatag cgcctggtta tatctttaaa acagaattac
    51781 aaccagagga tctacaaaat gtagagatca gtttgggctg gaactcagac taccaagaaa
    51841 aactattagc ctcttctacc ttgaaatggg tccaatctat ctcagctggt gttgatcagc
    51901 taccccttga gactttttca aagaaacata ttttactttc aaatggtagt ggcatccaca
    51961 gtgaatcgat tacggagcat gtcttaggaa tcatccttgg gtattctcgt ggtctttttc
    52021 aagcacaaaa ggcacagagt gacatgaaat ggttaggttc atcggtccat taccaatcta
    52081 tccaagggaa aaaaatacta atcattggaa ctggccatat tggaaaaatg attgcaaaaa
    52141 aatgcaaagc attagacatg aactgctatg gaatcaatac atccggtcat ccagcagaag
    52201 gaatggaaaa gactttttct ttaaatcaac taaaggaagt tcttcctgaa gtagatttcg
    52261 tagtcaatat cttacctcta acggaggaaa caactgggct ctttgatcag catatgtttg
    52321 aacactttga tccaaaatct gtattcatca atgttggccg tggtgcttct gttaagacac
    52381 aagatctggt gcaggcttta aataaccagc aactttcctt tgcagcatta gacgtttttg
    52441 aggaagagcc tcttccacaa gatcatcctc tttggaaaat ggacaatgta ctgattactt
    52501 cccacattgc aggtttgaca cctgattttc aaaagaaatt aatggctatt tttttaacca
    52561 atctgaaaag ctactttgcc acccatgagc ttcaaaccaa tcaagtaaaa ttgtctgcag
    52621 gatattaata gctgaaaaca atattttcaa aagaaaaaag agaaggtgac aaaaattgtg
    52681 tcaccctctc tttttttatt gttttttaaa gtgataggtt ggctcctcca ggttgggatt
    52741 ataatcaaca agtaaatcat atcctttaaa gaaccattca tctgcttcct cgataaaaaa
    52801 aagtgtccca tcaatttcca ctttctttac aggatgttct ggctgttcaa ctgacattcc
    52861 aatcgaaaaa ccatcatgaa cctctgtttt gccgtagact tttccaaaaa aacgtattcc
    52921 gtaagtttct ggcagatcaa tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt
    52981 taatttcatc ccaacaacct actttctctt ttctttctat tgattcatct tatcgtctag
    53041 aatatccaca tcgcctgtct ctccaataac cagtagatta tcattttcac gaacatattc
    53101 atctgctgca ggagaagcga taaccgtttg atctactctt cgtatggcga ctactgttaa
    53161 gtcaaaacgt tgcctgaaat ttaattcagc taatgttttg ttgaaaaatt taggattgga
    53221 gactcggatt tctgctaaag aatatttatc tgacaactct aggtaatcta aaatattctt
    53281 tgacactaaa ttatgcgcaa tccttattcc catgtctcgc tcgggatgga cgacgcgatc
    53341 agctccgatc ttttcaagta ctctggcatg atactcattt tgggcttttg ctaaaatatt
    53401 tggtacgccc atttccttta ccatcagagt aactaagata ctggcttgaa tatcttctcc
    53461 aatagcgaca attacatgat cgaaatttct tatgcctaat gatcgaagtg tcatttcatc
    53521 ctgtgcattt gccacaacag catgagtggc tatattcata tattcattga cccgatcttc
    53581 attactatca atagccagta cttcttgacc agcttcgatc agtgttcggc agatacttcc
    53641 gccaaatcgt ccaagaccta caattgcaaa attttgtttc accgttttcc tcctttagta
    53701 tcttcttttc tcagtataac aaagccttta caaaaacaaa agcaagcatc attattgtaa
    53761 aaaagccaag aaaaataata gttattttct cagcttttga ttatcctctt tatcatcgtt
    53821 tttatttcac caaaccatgt ttgaatgcat agatagcggc ttgtgtacgg tcttccactt
    53881 ctagcttagc caatatattg gaaacatgtg tttttactgt tttcagtgta ataaacaatt
    53941 cgtccgctat ttcctgatta ctttttcctt cagaaatcag cattaaaatt tcattttccc
    54001 gattcgttag ttcttcatgt aatacaggct catttcgccg actcattttt tccatcattt
    54061 ttgttgtcac ttctggttct aatactcgct cgccacgttg cgttgccctt atagcatcag
    54121 caatttcatg tgcggtagag gtcttcaaca aataccctgc tgcacctgct tcaatggcag
    54181 gataaacttt ttcgtcatca ataaaactgg ttacgataat gattttagct tctggccaat
    54241 cttttaagat tgcttttgtt gattcgatac catccatttc ttccatgact aagtccatta
    54301 aaatgacgtc cggtcgaagt gtcatcgcct tctcatagcc ttgtcgtcca ttttcagctt
    54361 ctccaattac ttcaatgtct tcttgaatag ataaataaaa agagacgcct aagcgcacca
    54421 tttcatggtc atctactaat aaaactttta tcatccttat ctatgcctcc ttcatcaaag
    54481 ggaccttgat ttctacactt gtaccttgac ctttaaaact aatgattttt actgttccac
    54541 caataccagc tactcgttct ttgatattgt tcaatccata acttcccgtt ttcgtttcat
    54601 tcatattaaa ccctgttccg tcgtcaataa tacgtaacaa aagattattg tctattttgt
    54661 gcaaatatac ctctaattca ttggctttag catgtcttaa tgtatttgat aacaattctt
    54721 gaacgattcg gaacaagtga tcctcaatgg aactagatag ttttacatct tctacatccc
    54781 atttcagcga aatctggatt ttattttgca attccttcaa taactgctcg ataccttgct
    54841 ttaaactttt ctcttctaaa ttgactggac gtagatgaag aagcagcgca cgcatctcag
    54901 actgggaagc gttgatgatc tctgctacca ttttcaactg cttgcgaaac atttctggtg
    54961 tctcgctttt ttctgcttgc tccgtcaatg ccgacatcat catcattgct gcaaacaatt
    55021 gttgcgaaac tgaatcatgc agctcacggg ctaatcgatg tctttctaat tctaaaattt
    55081 cttctttggt ttgtccatct acatattggg gacggctcgt tacaatttgt aattcactag
    55141 atacttcaat cattttttct tttatcttag tgatttcctt atcaatatct ttgatgtata
    55201 aatcgtccga tgcacttggg atcggaagaa gcaacaattt ggattcataa ttgccagaag
    55261 aaagtgcacg cagcttttct tcgattttcc cgtattttgt cttttgaata agtgataata
    55321 atagaaagac aattaatcct acacctaagg aaatggctaa caaatggaag ataagcggaa
    55381 catataataa acgtgcacgc agtaattctc cccaccaatg actttgattg ctggcataaa
    55441 aataagtgaa aagtgaaaat agaataataa ggaaagccgc aatccccgaa taaacagcta
    55501 gcatcgctct ggatattttt cccatcatat tcgtatcacc tcgacatctc caatcaaggt
    55561 attagtaata atcttcaatc tacgagggtt ttcatcataa tcactgctgt agattttgat
    55621 ttgttcattt ttcaaagaaa attgctcttc ttcaaacaag acatttccta ctaatgtcgc
    55681 atgctctaat cggatggcta cgcccaaagg tactaagatc cgtgttctgc ctatcccttt
    55741 tcttacaatc acaatattat catcttttgg caaaagcgta ttgcccaaat ctatgatagt
    55801 atcaccagaa atgacggcga tgttgatatc gtcccattca tagacgtcgt ttccaatacg
    55861 ttggttaccg aataattgct gtcttttccg ctcattatta tgtgttttta attgctctgt
    55921 ttggatcatc atgatctgtt tctttcgcca aaaagcattt ttggttaaat ctatccctga
    55981 aatctctaca cctttcagac caataaataa aacggcaaat acagccatca tccataaagc
    56041 aggactgttg actaagctaa aaaaaatgac caaacttcct aatatcaatt gaaaattttg
    56101 aaatttagta cgaggatgtt tgcgcatagc tagatatata ttgaaaatac cgaatatcac
    56161 taaaagcaaa agtccagtat tgtttacgat ttgccaaaca gcaaataaca gcagtagtgc
    56221 ttcaactacc acaaaaaaac gccaagaact attcatcgct ctttctccct cctgacacat
    56281 tctcatttca tcatacctat ttttttaact gttggctata ggactttaga tgtaagatcg
    56341 tttgttgaaa tctaaaatac acaaagagaa aaagatctag agtgtatcat cagtaagatg
    56401 aactctctag atctttcagt cagactacgc ttgttctact ttgacgattt taactaacat
    56461 atcgccacct ggagtagcaa tagttacttc atcattttta cgtttgccaa tcaatgcttg
    56521 cgcaatagga gaatcattgg aaattttgcc agaaaacgga tctgcttcag cgcttccgac
    56581 aatcgtgtac tcttcttctt ctccatctgg tagttcgatg aatgtaactg ttttaccaat
    56641 tgatacctca tctgcatcta caccgtcgtt atcgatgatt tgagcaaaac gaatcatatt
    56701 ttcaattgtt gtgattcttc cttcaacaaa tgcttgttca tctttcgctg attcatattc
    56761 agagttttcg gaaagatctc cgaaaccgcg ggcaattttg attcgttcaa tgatttctcc
    56821 gcgtttgact gtttttagtt cttctaattc tttttctaat ttttctttac cttctagagt
    56881 cattggataa actttctcta ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa
    56941 aggtaatctt ttgaggaata tagtccaaaa aagattacca cgcttttctt caaatgtaaa
    57001 tgtttttcta aaaatgatca atgtctagag cctgtttttc taagaattat ttacatattt
    57061 ttccactaat tccatatgtt cttcataagt tttagcgaaa taaacatttc cagtgctcgt
    57121 atctgctacg aaataataat agtcattttc tgctggttct aatactgcct tgattgcctc
    57181 ttcgcttgga ttgtcaaaag gtccaggtcc atagccggta ttggtataca aattatatgg
    57241 tgaatctaca gctgtatctt catacgtcac taattctttg tgttcaccta atgcgtataa
    57301 aacagagata tctgactgaa gtggcatatt tgctttgatt cggttaaaga agacttgtgc
    57361 aatgttttta cgatcatttt cttttacgcc ttctttttca actagagaag ctagagttaa
    57421 aacttcttgt acagtcaaat ttttctgctt gatagctgaa taatagtttt gcatgaccgt
    57481 attcgtcttg ttcaccattt caatcactag atccttaagc gaagtactcg tgtaataatc
    57541 atatgtggct gggaataagt aaccttccaa acggtatttt gtgttctcag ctttagatgc
    57601 actttccaac agttctggga atttttggtg caactcgtta aagaaagtct catcattcac
    57661 taaatctaaa aattctttct tgtctttacc agttaccttc gctacccgtt cagcaatctg
    57721 atcgatatcg tacccttctg gaatggcaat tttcccatct gcaacttttg ttggctcaga
    57781 agtaccgcct tcttgcaact gtttgccaat ctcgtcaaga gtcatattag gcgctaactg
    57841 ataatagcca gcttgaaagc cagttaaatt tttaaatttt gtataataat tgaaaacaat
    57901 cccgctttta ataatattgt ccttctccaa aatctcacca atctgcttgt tagaagagcc
    57961 actcgggatc tcgacttgga ctaattggtc atctgattta tctaaaggct tcaacccgct
    58021 atctacataa cgatacacgg taaatccaag aaatccgcca ataatcaata atgtaagagc
    58081 aatcactaaa atgatcttcc tcacaatctt atcttctttt ttacgcagat ttctccgctt
    58141 gtcgattata tctgctgtag ctgccttact ggcttctttt ttatctttac ttgggtgttg
    58201 tttgtttcct gacaaaacaa ctcctcctta ctatcaagtt cgtaacttta ttcattatac
    58261 atgatatttg aattggcgtg aatgatttta tttaaatatt ctatcaaaaa tgt
//
LOCUS       DAFLWZ010000012        57699 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000012 DAFLWZ010000000
VERSION     DAFLWZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.012"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(94..1137)
                     /locus_tag="L1V38_000751"
     CDS             complement(94..1137)
                     /locus_tag="L1V38_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBN1315324.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1514..2479)
                     /locus_tag="L1V38_000752"
     CDS             complement(1514..2479)
                     /locus_tag="L1V38_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBN1315325.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2713..3558
                     /locus_tag="L1V38_000753"
     CDS             2713..3558
                     /locus_tag="L1V38_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1315326.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3749..4936
                     /locus_tag="L1V38_000754"
     CDS             3749..4936
                     /locus_tag="L1V38_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1315327.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4942..5298
                     /locus_tag="L1V38_000755"
     CDS             4942..5298
                     /locus_tag="L1V38_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBN1315328.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5300..5638
                     /locus_tag="L1V38_000756"
     CDS             5300..5638
                     /locus_tag="L1V38_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBN1315329.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5714..5970
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6033..7067
                     /locus_tag="L1V38_000757"
     CDS             6033..7067
                     /locus_tag="L1V38_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315330.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7060..7746
                     /locus_tag="L1V38_000758"
     CDS             7060..7746
                     /locus_tag="L1V38_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315331.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7770..8618
                     /locus_tag="L1V38_000759"
     CDS             7770..8618
                     /locus_tag="L1V38_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1315332.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8815..9588
                     /gene="sufC"
                     /locus_tag="L1V38_000760"
     CDS             8815..9588
                     /gene="sufC"
                     /locus_tag="L1V38_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBN1315333.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9601..10887
                     /gene="sufD"
                     /locus_tag="L1V38_000761"
     CDS             9601..10887
                     /gene="sufD"
                     /locus_tag="L1V38_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBN1315334.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10884..12119
                     /locus_tag="L1V38_000762"
     CDS             10884..12119
                     /locus_tag="L1V38_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1315335.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12106..12576
                     /locus_tag="L1V38_000763"
     CDS             12106..12576
                     /locus_tag="L1V38_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBN1315336.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12581..13972
                     /gene="sufB"
                     /locus_tag="L1V38_000764"
     CDS             12581..13972
                     /gene="sufB"
                     /locus_tag="L1V38_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBN1315337.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14070..15212)
                     /locus_tag="L1V38_000765"
     CDS             complement(14070..15212)
                     /locus_tag="L1V38_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1315338.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(15263..16060)
                     /locus_tag="L1V38_000766"
     CDS             complement(15263..16060)
                     /locus_tag="L1V38_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1315339.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            16262..16561
                     /locus_tag="L1V38_000767"
     CDS             16262..16561
                     /locus_tag="L1V38_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315340.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            16826..17701
                     /locus_tag="L1V38_000768"
     CDS             16826..17701
                     /locus_tag="L1V38_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315341.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            17698..17916
                     /locus_tag="L1V38_000769"
     CDS             17698..17916
                     /locus_tag="L1V38_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315342.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            17903..20530
                     /locus_tag="L1V38_000770"
     CDS             17903..20530
                     /locus_tag="L1V38_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315343.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            20545..20763
                     /locus_tag="L1V38_000771"
     CDS             20545..20763
                     /locus_tag="L1V38_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315344.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            22282..22596
                     /locus_tag="L1V38_000772"
     CDS             22282..22596
                     /locus_tag="L1V38_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315345.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(22649..23422)
                     /locus_tag="L1V38_000773"
     CDS             complement(22649..23422)
                     /locus_tag="L1V38_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315346.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            23527..23772
                     /locus_tag="L1V38_000774"
     CDS             23527..23772
                     /locus_tag="L1V38_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1315347.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            23928..24779
                     /locus_tag="L1V38_000775"
     CDS             23928..24779
                     /locus_tag="L1V38_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBN1315348.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            24812..25486
                     /locus_tag="L1V38_000776"
                     /pseudo
     CDS             24812..25486
                     /locus_tag="L1V38_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            25743..25931
                     /locus_tag="L1V38_000777"
                     /pseudo
     CDS             25743..25931
                     /locus_tag="L1V38_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25977..26942
                     /locus_tag="L1V38_000778"
     CDS             25977..26942
                     /locus_tag="L1V38_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315349.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            26964..27176
                     /locus_tag="L1V38_000779"
     CDS             26964..27176
                     /locus_tag="L1V38_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1315350.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            27251..27727
                     /locus_tag="L1V38_000780"
     CDS             27251..27727
                     /locus_tag="L1V38_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1315351.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            27724..29532
                     /locus_tag="L1V38_000781"
     CDS             27724..29532
                     /locus_tag="L1V38_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1315352.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            29609..29824
                     /locus_tag="L1V38_000782"
     CDS             29609..29824
                     /locus_tag="L1V38_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1315353.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            29916..30779
                     /locus_tag="L1V38_000783"
     CDS             29916..30779
                     /locus_tag="L1V38_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315354.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            30816..31352
                     /locus_tag="L1V38_000784"
     CDS             30816..31352
                     /locus_tag="L1V38_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1315355.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            31366..31788
                     /locus_tag="L1V38_000785"
     CDS             31366..31788
                     /locus_tag="L1V38_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1315356.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            31718..34117
                     /locus_tag="L1V38_000786"
     CDS             31718..34117
                     /locus_tag="L1V38_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1315357.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            34149..36140
                     /locus_tag="L1V38_000787"
     CDS             34149..36140
                     /locus_tag="L1V38_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1315358.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            36163..36414
                     /locus_tag="L1V38_000788"
     CDS             36163..36414
                     /locus_tag="L1V38_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1315359.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            36404..37633
                     /locus_tag="L1V38_000789"
     CDS             36404..37633
                     /locus_tag="L1V38_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1315360.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            37630..39711
                     /locus_tag="L1V38_000790"
     CDS             37630..39711
                     /locus_tag="L1V38_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1315361.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            39860..43780
                     /locus_tag="L1V38_000791"
     CDS             39860..43780
                     /locus_tag="L1V38_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1315362.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            43781..44725
                     /locus_tag="L1V38_000792"
     CDS             43781..44725
                     /locus_tag="L1V38_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315363.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            44729..44932
                     /locus_tag="L1V38_000793"
     CDS             44729..44932
                     /locus_tag="L1V38_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1315364.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(45232..45468)
                     /locus_tag="L1V38_000794"
     CDS             complement(45232..45468)
                     /locus_tag="L1V38_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315365.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(45651..46037)
                     /locus_tag="L1V38_000795"
     CDS             complement(45651..46037)
                     /locus_tag="L1V38_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1315366.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(46019..47347)
                     /locus_tag="L1V38_000796"
     CDS             complement(46019..47347)
                     /locus_tag="L1V38_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1315367.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(47308..47637)
                     /gene="mobC"
                     /locus_tag="L1V38_000797"
     CDS             complement(47308..47637)
                     /gene="mobC"
                     /locus_tag="L1V38_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1315368.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(47895..48265)
                     /locus_tag="L1V38_000798"
                     /pseudo
     CDS             complement(47895..48265)
                     /locus_tag="L1V38_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            48410..48595
                     /locus_tag="L1V38_000799"
     CDS             48410..48595
                     /locus_tag="L1V38_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1315369.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            48753..48920
                     /locus_tag="L1V38_000800"
     CDS             48753..48920
                     /locus_tag="L1V38_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315370.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            49538..50197
                     /gene="vanR"
                     /locus_tag="L1V38_000801"
     CDS             49538..50197
                     /gene="vanR"
                     /locus_tag="L1V38_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1315371.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            50200..51561
                     /gene="vanS"
                     /locus_tag="L1V38_000802"
     CDS             50200..51561
                     /gene="vanS"
                     /locus_tag="L1V38_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1315372.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(51652..52953)
                     /locus_tag="L1V38_000803"
     CDS             complement(51652..52953)
                     /locus_tag="L1V38_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1315373.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            53232..54038
                     /locus_tag="L1V38_000804"
     CDS             53232..54038
                     /locus_tag="L1V38_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1315374.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            54056..54763
                     /locus_tag="L1V38_000805"
     CDS             54056..54763
                     /locus_tag="L1V38_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1315375.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            54760..55731
                     /locus_tag="L1V38_000806"
     CDS             54760..55731
                     /locus_tag="L1V38_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1315376.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            55724..56752
                     /gene="vanB"
                     /locus_tag="L1V38_000807"
     CDS             55724..56752
                     /gene="vanB"
                     /locus_tag="L1V38_000807"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1315377.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            56758..57366
                     /locus_tag="L1V38_000808"
     CDS             56758..57366
                     /locus_tag="L1V38_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1315378.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(57432..57605)
                     /locus_tag="L1V38_000809"
     CDS             complement(57432..57605)
                     /locus_tag="L1V38_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315379.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT        17025 a        12358 c        13801 g        14515 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa aaatttgaga
     1321 agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt acgacctctt
     1381 ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta caaaaacatg
     1441 aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt ttcacaacct
     1501 attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg ctatgttctt
     1561 taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt gcaaacagac
     1621 attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg ttgaagtaat
     1681 gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag gctgcatagc
     1741 ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg aaatacaata
     1801 cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca aagtttttaa
     1861 gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc ggacgtgtcg
     1921 gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat aagaacgcat
     1981 agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag ttcccggcag
     2041 ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa attgcttcaa
     2101 ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg atcacttgga
     2161 agataacagc gcacagccaa atgaatttga caattggtgc aatactttca tatgaaacaa
     2221 aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag gcgatgattg
     2281 gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca aaaatgaata
     2341 tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg tgatagtctt
     2401 taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg atcggaataa
     2461 ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt ttagtaccaa
     2521 gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag cagacagctg
     2581 attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca tttctattat
     2641 agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat aaaaagttat
     2701 ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga aacaagaaat
     2761 ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa tcaaatcaaa
     2821 cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa agagatgctt
     2881 ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga agaatgggaa
     2941 gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg gatcgttgct
     3001 tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat caaaaggttt
     3061 cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga acaagtagcg
     3121 aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg cgtacaaaga
     3181 tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa attgtggctt
     3241 gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga agagatgaat
     3301 atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt gctgaaggaa
     3361 ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc aatgactccg
     3421 ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc tgatcagctg
     3481 ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc tcacagcgag
     3541 gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat acactaaaga
     3601 taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga aagttaattt
     3661 ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata ataatcagca
     3721 gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt cgaacgataa
     3781 tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg gtctgctctc
     3841 attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag gcgtagggat
     3901 gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc atttgaattc
     3961 caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg taatgggact
     4021 cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa actggtttcg
     4081 attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca tcttgatgat
     4141 ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga aatcggactt
     4201 ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga tcatggccca
     4261 agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt tcctgatgtc
     4321 tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg ttggagcagg
     4381 aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag ttggattcaa
     4441 atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata cgtcaggaat
     4501 gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt ttggtaaagg
     4561 attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt ttaccgttat
     4621 cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt ttattttaat
     4681 ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct atatcgcaag
     4741 cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa atatcggatt
     4801 acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct cgattttagg
     4861 gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag cacctgcaag
     4921 atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg ttcaacatgc
     4981 aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt tgatatgatc
     5041 aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca agtaccaatc
     5101 cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa agatcaagta
     5161 ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat gctgatcaag
     5221 cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga aaaaatttat
     5281 gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca acctttggat
     5341 cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag aagaacttgg
     5401 agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag atgaacctct
     5461 gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa cgggtacagt
     5521 ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt cagatgaaat
     5581 gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg aattataaaa
     5641 tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa tcataagcaa
     5701 tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg tttgaagaga
     5761 gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta gagcagagta
     5821 agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt atacggaaag
     5881 aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa tcaaggtggt
     5941 aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag gcttttttgt
     6001 ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta acgaatgtca
     6061 aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt tcactaaacg
     6121 ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa agtacattag
     6181 tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta aacgatcaag
     6241 atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc ggtatgatct
     6301 tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag ctgccgctgg
     6361 aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg ttgcgtttag
     6421 tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga cagaaacaac
     6481 gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt gatgaggcta
     6541 ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta gcgatcaata
     6601 agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc cgcaaaatct
     6661 gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac gtattgactg
     6721 tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac atcgaaccag
     6781 aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc ggccgtttgg
     6841 caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa gcgattcgac
     6901 gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa gaaggttcct
     6961 ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa gcagaagtgt
     7021 tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag cttttcagaa
     7081 acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat ccttgataca
     7141 ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt tttgggattg
     7201 atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta tggaatcgta
     7261 tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt tttgatcatt
     7321 ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat tccagctctt
     7381 gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg tgaagtcagc
     7441 cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat catctggaag
     7501 gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac aacgatctcg
     7561 atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg aggtcttgct
     7621 tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac tttaattatt
     7681 ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa aacagacaaa
     7741 agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga tttgcagcag
     7801 cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc aaagattcag
     7861 caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg cacgcagaga
     7921 ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa atcgtcaaat
     7981 tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat gccaattact
     8041 tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac tttgtcaatg
     8101 ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa gatgtttccg
     8161 aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg ggacgcatca
     8221 tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat ctggaaacag
     8281 caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat acgatcgacc
     8341 catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca atcaacgcaa
     8401 acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt gaaaaggaca
     8461 actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt gacaaaatca
     8521 aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca gacaaatggg
     8581 gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa aaaagatgag
     8641 aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat ttagaaatca
     8701 aaattgttta ataataaata aaagatattt gattttagta aggaaggtca ttgcgcttca
     8761 ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata atgcatgtct
     8821 gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct taaaggcgta
     8881 aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg cacaggaaaa
     8941 tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga aggcgaaatt
     9001 ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg acttggctta
     9061 tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga attcatgcgt
     9121 gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc atttttgaaa
     9181 aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga acgttatctg
     9241 aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt gttgatgtta
     9301 gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga tgctttgaaa
     9361 gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt gatcatcacc
     9421 cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat gatggaaggc
     9481 cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga aggctacgct
     9541 ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg gggagcaaga
     9601 atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc tttaagtaaa
     9661 ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc agatgaactg
     9721 ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga tgtgaaagaa
     9781 acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa agacaatcct
     9841 gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga attagcagaa
     9901 aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga actagtccaa
     9961 gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc actccatgta
    10021 gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat cgatgaacca
    10081 ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa gcatgtgttg
    10141 atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac aaccaaagaa
    10201 caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc tggttcaaaa
    10261 atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat gaatcgccgt
    10321 gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa tgacggtcat
    10381 gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga agtcaaaatc
    10441 gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac caataaagcc
    10501 cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg aacattgacc
    10561 tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca acaagaaagt
    10621 cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct tttgatcgat
    10681 gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc agaagaaatg
    10741 tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt gattcgagga
    10801 ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga attagtcgaa
    10861 gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat gattttccta
    10921 tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca gcgacgaccc
    10981 aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat aacgccaatg
    11041 ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa caagcaagag
    11101 aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt actcgtggta
    11161 cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc aaagcaggag
    11221 acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg cagcagttgg
    11281 caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc ttcctggata
    11341 tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt gctcatgtat
    11401 ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc catgaaaacg
    11461 gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt gatgtccaag
    11521 cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca acaggtattg
    11581 gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa tttggtggcg
    11641 aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct tggaaattcg
    11701 aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc gattatttgc
    11761 aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct tatgtgttgc
    11821 caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg aattttcgga
    11881 caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg acagctttag
    11941 acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta ttgaagtacc
    12001 ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg caagacgccg
    12061 accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg actatctaaa
    12121 ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca tcatcgtgga
    12181 agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg agatgtgatc
    12241 gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga cggcagtggc
    12301 tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg aaaatcaata
    12361 gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa agaagtcaaa
    12421 gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt tcccgctcgg
    12481 atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa cgatggtacc
    12541 gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac cagaattaga
    12601 agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag gagaaggctt
    12661 gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat ggatgcttga
    12721 attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat ggggccccga
    12781 cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg acaaacccgc
    12841 tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga ttggtatacc
    12901 agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag aagtcgtgta
    12961 ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca ctgactctgc
    13021 tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac cgccaaccga
    13081 caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta tttacgtgcc
    13141 aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg cggaaaacac
    13201 ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc actatgtcga
    13261 aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg tagaaatctt
    13321 tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag acaatgtgta
    13381 caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat ggatcgacgg
    13441 aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg gaaaaggtgc
    13501 acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag atacgggtgc
    13561 aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat caatttcaaa
    13621 agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca gtgcgggttc
    13681 gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat ccgatacgat
    13741 cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca aagtctcaaa
    13801 aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat ctgaagcaac
    13861 tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa tggaatatgc
    13921 agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt aataactatt
    13981 tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg tattttaatg
    14041 gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc aaatcggtca
    14101 ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt agttttaata
    14161 tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc aaacaataag
    14221 ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg tgtctttttg
    14281 taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt tgtgtttgta
    14341 gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat tattttcatt
    14401 tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg aatcgttctt
    14461 gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc ttgagcgata
    14521 gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg aagcgccaat
    14581 gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta cagtttaact
    14641 gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt gtaaaacttc
    14701 aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg attatcctta
    14761 cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct caagaaacca
    14821 tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct aacacttatt
    14881 ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa acgttgagca
    14941 acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa ttcatacaac
    15001 tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc tacaagtagt
    15061 ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt tgtacgtata
    15121 tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata tttttcgcca
    15181 ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt cattattgca
    15241 ggtagagaag ttatttgaag aatcaattat ttttaaattt atcgtgatta tcagttaaaa
    15301 attttgcgat tatactattt ttctcatatg ggaaattgta ttttttacta agatctgaaa
    15361 taaatttttc tgtttcaaat tggtttttag taattttata aaagaaatcc tcgacagatg
    15421 aatactttga aatatcttta taggctaagt ccatttcgtc taatagctgt tttaaagaat
    15481 caatcattct ttctttttca ccgtatttga aatcaccatt tcttatcttg tcttgaagtt
    15541 tactgttggc tcttttgaaa aatagctctt tagagataga gtgtctttgg ttagcgtact
    15601 cttcaatcag aggattgata ttattagcaa gtatctcatt tagataaatt tcaaaatctt
    15661 ttgagtaata ttttgtaaat atatttttta ttataggatt caataactca tagtctttat
    15721 ctagcgaaaa cgtatcacta tatctttctt gaatgtcttt aaagactttg tgaggtattt
    15781 ctgggaagtc cttaatatat agctcatacc ctatatcgat aaggtatgaa gttatatatt
    15841 cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt gataataatt
    15901 tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg gtcgcacgtg
    15961 gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa aggcgtaatt
    16021 gtttgattcg ttttcctgct tctgaaggat ttggcttcat cttttttctc ctttttattt
    16081 ttaaagatag tatatcatat ttataaaata aaagtattta aaagtattta ctttttatct
    16141 ggagtatgat actttattct tataaataca aataaataca tttttttacg caatttgtat
    16201 ttatttgtac ttataaaggt agaggagtta tagaataatt aattaaaaag gagaggtttt
    16261 tgtggaagca ataaaattaa tgatttcaga agaacaggag gaaatgtttc taaagcagtt
    16321 ttatcaaatt gctacaaaag ctattgaaaa ggctcaagaa aatgcgggga tgacaaggga
    16381 atatctcaat caaaaagaaa tggcggaata cttaaatgtg agtgaaaact ttttaaaaaa
    16441 tgctgtgaga aatgagggat tgcccgtagt tgaattaggg gcaagaaaat tttattcgaa
    16501 aaaggcagtt aatgagttta tgtttgctcg aatgaaaaga ggggaaaata ttggaagatg
    16561 atgaagtaga aattataaaa aaatgcttta aaaaaagaaa aaaagtgttc ccaaaagttt
    16621 gcagactggg ggaacactca ataataaagt gctgagaaaa ctttatttat agctattata
    16681 tcaaaaaaga aggtgaaaag gtgttttctt ctggaaatgt tgtagttgac aaacttagag
    16741 aaataaattt tgacggaaat gtaatccaca cacatggtac gatcaattaa gaaaaaaaac
    16801 gaaaaaaggt gttgagaagc cctatttgaa tgcaatagtt atcttagcag aaattaccta
    16861 ttggtataga cctaaaaaaa tttttaacga tgatggtcag ctacttggtt atcaaaaaaa
    16921 gtttcttgaa gatattttgc aaaaatcata taagcaatta agcaaaaaaa caggattatc
    16981 agaacgagct ataaaagatg caattgtgta cttagagaaa aaggggatta tcaaaagggt
    17041 ttttagaaat atttattatg agaaaagagc agttacatta tcaaatgtta tgtacattgt
    17101 tttaaatgta cataaattga tagaaattac ttttcctact ttggattgcg aaaaaaagga
    17161 gtatatgccg aaaattcgtc agaggggtat cgaaaaaaag agatatgtct ctttaaaaaa
    17221 aggtagaggt atgtacaaat ttgtatatac gtatacaaag actacttcac agaacatatc
    17281 aaagactact ctcgttatgg aagaagagga tattaatata aagaggattt acagtaagat
    17341 tagtgttctt tatgacgcaa ataacgaaga tggtcgaaaa ttatttcaag tgtatcacta
    17401 tttgagaaac gctaatgtag atacagaaga tatcagaaaa atcattgaat atttatctga
    17461 aaatactcag tatcttattg ctgagtgtat tataaaacaa catgaagcat gcttttttca
    17521 aagaaaaact gaagaagggt tatacgatta tgtaacatat tttttgaatg gacttcagaa
    17581 aagatataaa agtcaatttt tagaaaatgt agagcctata gatcagttca aaaaagcttt
    17641 cgaaatcaaa gagttacctg aaattactat gcataattgg ttgaaaggag aagaatcatg
    17701 attaaaaatc gcttaataga tcaaatgtgg tgtcttgatc aaaatacaga tactctcgaa
    17761 ttaatcgaga gtatctgctt caacacagta gttctcgatt taagagctga aaatgacaat
    17821 tgtgtaactc atatcataat taatcaaaaa atggctcagc agctctctga gagcctaaga
    17881 aaatgggctg aaggagaaaa ctatgaaagc aattaaagaa aaaatcgtta gtagaaaaat
    17941 aaactggtta gcactcagtg tacttgtttt aatgattagc gttgttttta caagtaatat
    18001 tgttgaagct agcattttca attggtttga tgacacaaaa agtcaaacag agtttttgaa
    18061 taattctctt tatagacctt acctaaaaaa atacaatgga gatttcctta gtcagttcgg
    18121 gatttggctt ggatgggctg tggtaaaagg catgtttact gtgactgatt cgattcaaaa
    18181 tatgattcca gatgtgttgg atttgttcaa tttcattgaa agtacagggc taaataatgt
    18241 ttatcaatca gtcataaata caattgtcgt tggattaatg atcctttcat tgatgtttgt
    18301 tggctacaag atgattactg gaaaaggaac aatagattta agatctgttg gaatgaatat
    18361 agtgatgtct gtagcgttaa ttcttttaat gccaacaatg atttctagcg gtattcaatt
    18421 tgccaaaata ttttacaatg atgctactac gattacaaat tcagatgacg gagtcgcttg
    18481 gtcattgata aaacaaggag taacagatct ggcatatatt aataaaacag atcaatactc
    18541 aagcattgat aaaacggagg atcgaaataa gttaacacga aaaaattttc aacagacaga
    18601 tttaacacaa gtgttgacgg ataaagtgat tgataaattg gaaaaagaaa atccagctgc
    18661 ggataatctt cgctatgaat tagttgaaaa ttctaataat gaatttgttg ccacaaagtt
    18721 ttctgataac ttcttatcaa cattttctga tagcttgaaa tcaggttatt atcgatatca
    18781 agcaaatctt tgggggattt cgattgggtt gacagcgttg gcaatcgcct atgtgttcag
    18841 cgcgtttgtg atcattacag caatattaga acttgcattt aaacgtgtgt taggtgttct
    18901 tgtttttgcg acagatattg aaacaggaca acgttcaaaa gttgttttat ccgatatttt
    18961 acaatgttac ttaacagttg gatttcaagg gtttggacta tctatgtttg ctatgtttat
    19021 caatttttta aatgctggac aaggtatctc cacaaatatt tttataaaaa caattgctta
    19081 tatctgtgct gtgtttgtgc tgataaaagg cagtggaaca gtcatgagat actttggtgt
    19141 tgatattgga ctcaaagaag gctatgggca acttgcttct gcttttggta tgggcgcaat
    19201 gctgtttaga aaaggatcaa ctggatttaa tcgtgctaaa ggaagcggaa atggaaatgg
    19261 atcagacagt ggagaaggag aagatcgaaa accagaaaag aatttcggcg aaactctatc
    19321 aaaaaaagct ggcaaaactg gaagagcttt gggatatgcc catgaacgtg gattatcagg
    19381 tttagcttca gatggagcta caatggctag tgaaagagca ataaaaccat ttaagagtat
    19441 gcgtgatatg gctaatgata ccaagaataa gttcaaagaa ggtttagatg atggtacagt
    19501 gtccgctatt aataaaaata gcaaacctat gttagctaaa aataaagaag atgaaactgg
    19561 aaaatatgct gattccatgc caacacgtct ttcggataga aaagatggtg ctaaggttga
    19621 aaatgccgat agaattatgt ctagttctga acgtatgcgt gaagcaatga aaaataatgc
    19681 tgaatcgaat aataatcctg taagtgcaat tcagcaaaaa gttcaacaag atattgaaga
    19741 acgtaaaaat gctatgcacg gtcaagctaa gtctgctgaa gaattaatta atcagaagcg
    19801 acaagaagct aaatacacgc ctgaagcaat gaatcgtgag gaaatgttaa ggaaacgtgt
    19861 agaagggcgt acaggagcta atacggacga aaaagaagcg ttgaccaaag aaagaatcca
    19921 agaagctaaa aactcaaata ccggattaga aaaattggtc aaagaaaatc tacaaaattc
    19981 tacaagtagt caaggtggcc gatcagtaga tgtccgagaa aatattcaag gttcattgaa
    20041 tggtcatgtc ggacggaatg ttgatgtaag agagaattta caaagctctt caaatggtca
    20101 aggtactaag acaattgatg ttcgagaaaa tgtacaaaat tctacaagta gtcaagggtt
    20161 taaatcaatg gatgtaagag agaatgtaca aaattctaca agtagtcaag ggtttaaatc
    20221 aatggatgta agagagaatg tacaaagttc tacaagtagt caaggattca aaacagtaga
    20281 tgttcgggag aacgttcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa
    20341 tatcgttgaa gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat
    20401 tgatagtgaa atccgtgaaa atgataaggg atcaaaacca agacgaagat ttacctatga
    20461 agacaacgag ttattcagag atacacttaa tgatcctaat ccgcttttcg ataatctatt
    20521 aaaaaaataa aagggggaat tgtcatgaaa ttaattctaa agattagtac gcatgatttc
    20581 ttagaacttg acgaattatg tgaatcagta aagaacgcaa caaatgaaaa aatcacggtc
    20641 actaattata ttgaactgat gattcaagaa gaattaaaga tgaaacatga gataaaaaac
    20701 aacttgaaat attgttatct agaaaaaagt gaagagataa tccatgaatt aaatggcttt
    20761 taaaaattgt atttgacatg aatttacgac aaggaattag tggggattaa gcgattattc
    20821 tcttccactt tagagaaata atgggttaaa aagccagaat acgtagagca atattgacaa
    20881 cctataaagg agctattgtt gaaaattgaa gtaacaaaaa gataaaggga ggtttacatc
    20941 tatcagatta aaagtgatag tacacccatg aaacctgcaa aagagttgaa cctaatgtat
    21001 atcggtttaa ctctttttat ttgcaaatta aaaaaatatc accgaagtga cgaatgaaac
    21061 tatgaccaaa ttaagcaaga aaatatatct tgcaaataaa gtagtataaa aagatattga
    21121 taaagccaat caaaactttg aatttcaaac gttagataat caaacagata caaaaaatga
    21181 aatcagttct acgcgtacga ttattaaaaa taataaattt tcactagaag aaaatggaaa
    21241 taaaatcaaa taattaggaa gaaaaaacaa agcaattaga aaagcctgca agcaaatttg
    21301 agtaatcgag atccaatttt tttaaggaag tttaacaaaa atatgtaatt ctattatcac
    21361 tattaaagag aaagttggag cggaatataa agaaaagaga aaagtaatta aacgcaaaaa
    21421 aatgtagaac ttaaaaaata taaagaggaa caaccgttaa aattaggaat gatgttgtgt
    21481 aaacattata attgctatga tataaatgaa gtgttaaaga aagcaaattt aaaccaattt
    21541 tgtgaacaga aaagccttag tcactatgac caaaactacg gacgaaacta tgaccaaaag
    21601 taggtactaa attatgaccg aaaataggtc caaaatggat ttttttatga tatcaaaaat
    21661 tatgaaatga ttttgaaaga aaaccagttg gcacagccaa cttagccacc ttcctgtagg
    21721 aaggtgctat cagttttccc ttatgctctt ttctttcttt tttgtttcat atgtcaaatg
    21781 ccattttgaa atgtaccatc ttaagaaatt tatccttaaa aacaattgcg ttattggata
    21841 aaaagatgct acattatctt aaaaaaggaa tcaaatatga tgaatttagt ggctagcata
    21901 tcgtgtgatt aagatacttt atagtgtaag ttgaaggaga aaaaatattt aaaatatact
    21961 tcccatttca gtgggaagta aaattaatct tgttgtttct actagtaatg tatctttttg
    22021 gaaactatgt aacgatgtaa acaagatttt tttcagaaga aaaaacgata aaagttgtga
    22081 taaacgattt aaaaaatagg agaaaatata tcaagcgcat ggtatgaaac gcacatttaa
    22141 aaagattcga ctaactaaaa aaataagttt acaaagcatt gttgtgtatt acaagtgatc
    22201 tatacactga aaaatgatag agaaaatctg atacgtccgc aacaatggac aattgaaaat
    22261 gaaagtgagg aaattggaag aatggctgat gaaaataaag ttgttccgct tgaaacacta
    22321 gtgataaata aggaagagtt tgagcaactt tttcttgatt tttttgttca atatgacagg
    22381 atttatgatt ttagttcgtc actagattta tttgaattag aggcagaaat aatagaaaac
    22441 agtcgagagg agaatggtaa aatcatcatt tcagtagaaa aattcaatga attattctca
    22501 gaaacatttg aaatagatac agattattat caaccacaag aagttttcca atcatttaga
    22561 aatcagatta ttcgctcagg taagaccgta aactgaaaaa caataaaaga aacgttgaaa
    22621 gaataattat tccttcaacg tttctttttt agaatgtttt aatgaccaaa gcagtttcat
    22681 tgtcaggctt aggtaattca tgaaatcccg tatttatagt gctcaattga tcaactaacc
    22741 atgttttact ttttgaattg tagataaatc taaaattaat atcgttatta tcgtgttgaa
    22801 ggggcgtctc caaataatct gctgtatatt catagtcaac gtaacctgct aatacaaaag
    22861 agagtatccc tttatttaat gttagattta atggataatc atacgacttt atttttttca
    22921 acttcatatt gtacatatct tcagccataa aagttgagtt cgtgatttca tcttgggtct
    22981 cattaaaaaa gttatccgaa taatcgctta tttttgaaaa gtctttattg gcaccagcct
    23041 caaaaaattg ttcaactttt tcagtataaa gttgtgctaa cgctcctttt tcaatattaa
    23101 ctttaatatt ttcatgtcta tcaatttgtg tgctgttcag taagggaaga tcagctttta
    23161 gttttatatc gtcttgattt ctttcaattt caattggcaa aatcttttca gtagattcag
    23221 tttctgataa aggaacatct agttttttat catgataata agcttcaaat ccatctggaa
    23281 ccggaaaaaa atgtattggg taattctttt ctgaggttgt tgtactagtt tccgtacttg
    23341 tagaacttgt gtcagaagtg gtacacccgc ttatagttcc gatgagtaaa gcgcaagtta
    23401 gaatgattgc aaatttcttc aaaaaaattc ctccttaaaa ttgaatatgg actaatacta
    23461 gtcccattgt agcataccga atctttaaga ttaataagaa aaaggactaa ttttagtcca
    23521 aaaggtgtgc tattcttgaa agaggaaaaa attattgata aagaaaatgt aatcggtagc
    23581 aatattagac gagtccgatt agaaaaagga attggtcaaa ccgagctgat tagagaccta
    23641 cagcttcgta aaattgctat aactagggaa acgttggtta agattgaagg tggccgccaa
    23701 cacattaagt tggatcaatt gaaagccatc aaagatattc tacaggtgtc ttatgaagat
    23761 ttgcttcaat gactacttgt agtcatttcg tttgaaatta ttatgttaca cccttatgtg
    23821 tcacgaagaa atactggtat aataatgaat gggatatgta acgatagggt atactgttat
    23881 gttgcctaat aaattgtgga tcaaaataca agaatggagg gatatccttg tataaggcat
    23941 atgaattgga ttttacaaat gctgacttaa atgcattctc ctcaagctcg caatcatata
    24001 cacatgtagt aaatcaaata gatcacaacc aaaaatctat taacaagaga atagaaaatc
    24061 tatttgaaag tgaaaatgat ttagttgatt attattctaa ggacagcaaa attctagatg
    24121 cagacgaaat tattaaagat tggtttccaa ctataaaagc agatattttt atatctcact
    24181 ctcatgctga tgaaaaatta gctatacgtt ttgcatcatg gctatttgaa aattttggtc
    24241 ttactgcatt tattgattct tcggtttggg gatacagttc tgatttatta aaaaaaatag
    24301 accaaaaata ttgctataag gaacaaacaa aaacatatga ttatgataaa agaaatgtaa
    24361 caactagtca tgttcatatg atgctttcta cagctttaaa taatatgatt gatagtacag
    24421 aatgtctgtt ttttcttaat acacctaatt caattagttt gagcaatgaa atcactaatg
    24481 aacagaaatt tacgtattcg ccatggctat atagcgaact gacgacagct tcaatagtgg
    24541 aaaaaaagaa tccacgattg gaaagtaatc ctcaaatgag caccgaggat gttagaagca
    24601 ttataaagca ctattcttcg caagaaaatc tgcaaataaa atattcttta aatttaagtg
    24661 aattaactta tttacgaaaa gctgatttga aaaaatgggc tttagatgct gtggaatgca
    24721 ctaaaggaag taatacatta gatattttat ataaaaacac cattttcact aatctctaat
    24781 caatttactg aatcgaaagg aaccgggtag aatggataag aaagttttaa taaagaggtt
    24841 ctctgaagct attgaaaaag gaaatgcagc aatatttgca ggtgcaggat tatcgatgtc
    24901 acaaggatat gtaagttggc cggaactact taatgatcct gcaacagaaa tcgggttgga
    24961 ttctaaaaaa gaaacagact tagttactct ggctcaatat tataaaaatg aaaatggtgg
    25021 atcaagagga attttgaatc agatacttat ggataatttt ggtgaagaat tagaaatatc
    25081 tgaaaatcat cgaatactag caagtttacc tattgaaact tattggacaa ctaattatga
    25141 tcatctaata gaaaaatcaa tccgagaagc ttataaaaac cctcaggtta agaaaaatta
    25201 tactcagtta gcaacaacta atccaaatgt ggatacaatt gtttataaaa tgcatggtga
    25261 tatagatgat gtcagttcga cagtaataac aagagatgat tatgaaaaat atgatgattc
    25321 gtacgcgtta tttaaagaaa ctttaaaagg agatttgtta acaaaaactt ttctcttttt
    25381 aggatttagt tttacagacc ctaatttaga aagaatttta tcagatataa gatgggtttt
    25441 gagagaaaac caaagacctc attattgtat aatgagaaaa atattataga aaaaatttta
    25501 ggttatcgct gaaagccccg gaaatacggg catttcgcag gatatgagaa ctcaatttac
    25561 taccaattta ctactttcgg attgagccgc atatatgctg aaccatactg ctaatacccg
    25621 ccaccccaaa tacggcacat cataaattga atacgacacc gtaaacgcgg cgttcctctt
    25681 tcccgtcatg ggagaacagg acgccgcttt tttatgccca aatagagaaa ggaggcgacg
    25741 ccatgctatt tacttccggc cctgaccggg cgtttgaacg gctgatgcag gaaaagcccg
    25801 gtttcgatca ctacgacggc ggcggggcgg acgcgccgga ggattgcggc acctgccgat
    25861 tttaccgccc ggattggaaa tatcaattct gccagtttgc agagtgtccc tatcagccgg
    25921 gcaagctgac cgactatgca gcggtcaaat tcacagtgaa aggagcgaac aacgctatgg
    25981 cagttttccg tgtggaaaag aacaaaggct atacggtgat gtcaaatcac cacctgcgga
    26041 ataagaacct gaccttaaag gccaagggcc tgctgtcgca gatgttgtcc ttgccggagg
    26101 attgggacta taccctaaaa ggactgtcct atatcaaccg ggaaagcatc gacgcgatca
    26161 ggacagcggt atgggagctt gaaaaagctg gatatatccg gcgtgagcag ggccgtgacg
    26221 caaaaggcaa aatggccgat atggtctata ccatctacga acagccggta ttggaaaacc
    26281 cggtattgga aaatccaaca tcggataacc cggtgttgga aaatccgaca tcggataatc
    26341 cggcgtcgga aaatccaacg caattaaata aagaagtaca aagaactgac ttatcaaaaa
    26401 aagaaaaaat aattacagat ggacaaagta cccattccat tcctatccca tccccgaccc
    26461 ctgcccctat ggagggcgag gcagcggcta cgccgccgga acggaaaagg acaggaaagg
    26521 atgaggctgt acggatttat cgggaaatca ttttggagaa catcgagtat gcctatctca
    26581 ttcaggacag gagcattgac cgtgaacagc ttgacgaaat cgtagacctg atgctggaaa
    26641 ccgtctgcac cgcccgaaag acaatccgtg tcgccgggga cgactaccct gccgagctgg
    26701 tgaaatccaa gtacatgaag ctgaccggcg aacatatccg ctttgtcctt gactgtctgc
    26761 gggagaacac aacgaaagtc cgcaatatca aacaatacct gcgggctatg ctgttcaacg
    26821 cccccagcac catttccaac tactacacgg cccttgtcgc gcacgacatg gcacagcccg
    26881 attggggaaa gcctaaatcc ggcctgccgg actattcctg cggcgagggc gaaagcctgt
    26941 aacgagaaaa ggaggacgac cctatgaagc agggcgcatt gatttttgac gagcgaacag
    27001 accgttacga catccgcttt gatctggccg actattacgg cggcctgcat tgcggggagt
    27061 gtttcgacgt gatgatcggc ggcaaatgga ggcccacccg cattgaaatg gccgaaaact
    27121 ggtatcttgt cggcatccgg gccgacgacc tttccggcct gcgggtgcgg atttgaccta
    27181 tatctacctg cggcgtctgg tggttccgcc ttagacgccg cttttgactt tctgacaagg
    27241 agggatgcga ttgcaggaag aagttactca aaagaccatt gccctgtcca tgaaaacggg
    27301 caagctcacg gctcaagtgc tgcaagcggc gctgaaaaag tacctgcaac accgggccaa
    27361 gggcaaaaac acgctgcacc acggccagca gagcctaaag cagcttaaaa agcatggggc
    27421 tgatctctcc aacattgaga tcaccgaggc caacattgga gcgttcaagc catgcgccaa
    27481 gaaatacggc gtggatttta ccttacgaaa agataagacc acccagccgc cccactacgt
    27541 tgtgattttc aaggccaagg atgcagataa ccttgatctg gcgtttcggg agtttaccgc
    27601 caagacgctt tccaaggagc agcggccctc tatccgcaag gttttgtccg ctgtgaagca
    27661 aaaggcggcg gcccagacca agcagcgggc caaggagaaa atcaaggaaa gggggctgga
    27721 actgtgaagc ctgacgtaaa gaaattgctg atcctgaacc tcccgtatct gatttttgtg
    27781 tacctgtttg cgaaatgcgg ggaggcgtac cggctggccg ctggtgctga cctgtcgggg
    27841 aagctcctgc attttgcgga tggttttgcg gcggcttttg ccaacccgct gccaagcctg
    27901 cacctgtttg acctgtgtat cggtatcgcc ggtgccgtga tcgtgcggct ggtggtgtac
    27961 tgcaagagca agaacgtgaa gaaataccgc aaaggcatgg agtatggcag cgcccgctgg
    28021 gggacggcca aagacatagc gccttacatc gaccccaagt ttgaaaataa tatcctgctc
    28081 acccaaacgg aacggcttac catgaccggc aggcccaaag accccaagac agcgcggaat
    28141 aaaaacgtgc tggtgatcgg tggcagcggt tcagggaaaa cgagattttt cgtgaaaccc
    28201 aacctgatgc aatgctttcc gaccacggac tatccgactt cgtttgtggt gacagatccg
    28261 aaaggcactt tggttctgga aaccggcagg atgttccagc aggcgggcta ccgcattaaa
    28321 atcctgaata ccattaactt ttccaagtcc atgaagtaca acccctttgt ctacatccat
    28381 tcggaaaagg acgtgctaaa gctggtaaat accctgattt ccaacaccaa gggcgagggg
    28441 gaaaagtcag cggaggattt ttgggtgaag tcggaacggt tgttttattc ggccctgatc
    28501 ggctatatct ggtacgaggc cccagcggag gaaatgaact tctcaacgct gctggaaatg
    28561 ataaacgcca gtgaagcccg cgaggacgac ccggagtttc aaagccccgt cgatctcatg
    28621 tttgagcgtt tggagcagaa agaccccgac cattttgcgg tgcgccagta caagaaattc
    28681 ctgctgtccg caggcaagac ccgttcttcc atcctgattt catgcggtgc cagacttgcg
    28741 ccctttgaca tccgggaggt acgcgagctg atggaggacg acgaaatgga gctggacacc
    28801 atcggggacg aaaagacggt gctgtatctc attatgagcg atacggacac gacctttaat
    28861 ttcattctgg ctatgctcca aagccagcta atcaacctgc tttgtgaccg ggctgatgat
    28921 gtgtacggcg ggcggctgcc tgtccatgta cgcctgattt tggatgaatt tgccaacatt
    28981 ggccaaatac ccaatttcga taaactcatt gccaccattc gaagccgtga aatatcggcc
    29041 tctattattt tgcagagcca gtcgcagcta aaagcgattt acaaggacgc cgccgagatc
    29101 atttcggata actgcgatag tgtgcttttc cttagtgggc gcggcaaaaa tgccaaggag
    29161 atttccgatg cgctggggaa agaaacgatt gacagtttca acaccagcga gaaccgggga
    29221 agccaaacgt cccacggatt gaactatcaa aaattaggaa aggagttgat gtcccaagac
    29281 gaaattgccg tgatggacgg cggcaagtgt atcttgcagc tacggggtgt gcgcccgttt
    29341 ttatcggaga aattcgatat taccaagcat ccccggtaca aataccttgc cgacgccgac
    29401 aagaagaata cctttgacgt ggacagattt ttgactatca cgcgccggaa acggcagcaa
    29461 gtggtaacgc aggatgaagt attcgacctg tatgaaatcg acctgtcgga cgaggacgcc
    29521 gccgctgaat aaacagcggc ttttttcatt ccaacaacaa aatcaaaaaa tcattatgag
    29581 ccggaaaccg gcagaaagag gtaaatttat ggcatttttt aattccgcag ttactacttt
    29641 gcagactatc gtgatcggac tgggcggcgc tctgtgcgta tggggcggca tcaatctgtt
    29701 ggagggatac gggcaggaca atccgggggc aaaatcgcag ggtgtcaagc agcttgtcgc
    29761 tggcggcggc gtggccctga tcggtgtcac tctggttccc ctgctgtccg ggctgctggg
    29821 ctgatcctgg cctttgtccc tgtccaaacc cttaactaat cgcctccgcg tcctcccggc
    29881 cagaccggga gggcgcggga aaggaggtgc tacccgtgat tagtgaaatc attgaagaat
    29941 ggataaaagg catcctcatg gacggtatca cgggcaacct gtccgggctg ttcgatacgg
    30001 taaatgccaa agtcggagaa atcgccgccg acgtgggacg aaccccgcag gcatggaaca
    30061 gcggtatttt caatatgctg cacagcctgt cggaaaccgt gatcgtcccc atagccgggg
    30121 ccatactcgc ccttgtcatg tgctatgagc ttatccagat gataacggaa aagaacaata
    30181 tgcacgactt tgacagctcc atgttcttcc gctggatatt caaatccgcg tttgcaatcc
    30241 tgatcgtaac gaacacatgg aacatcgtca tgggcgtatt cgacgccacc caaagcgtcg
    30301 tcaatcaaag cgccggtgtg attatcgggc agacatccat tgattttaac accctgatac
    30361 cagaccttga aagccaattg gaggctatga gcgtgggcgc tcttttgggg ctgtggttcc
    30421 aaacccttgt tgtgggcctc accatgaata tcctttccat ctgcattttc cttgtgacct
    30481 atggccgcat ggtggaaatc tatgttgtca cgtcgctggg gcctatcccc cttgccacaa
    30541 tgggcaacgc ggaatggcgc ggcatgggcc aagggtatct gaaatccctg ctggcgctgg
    30601 gcttccaagc ctttttaatc atggttgtgg tgggtatcta cgcggtgctg atacagaata
    30661 tcggttccgc ttccgacata tccggcgcaa tctggggctg tatgggctat acggtgctgc
    30721 tgtgcttctg cctgttcaag accggcagta tatcaaaggc cgtattcggg gcgcattgat
    30781 cccaaaatcc aagcatacac aggaggaact tgtttatttc aacgtacaac atcatttacg
    30841 ctgacccgcc gtggcggtat gactgcaaaa acgtacaggg cgcagcggaa aatcactatt
    30901 ccaccatgag cattgacgag ctgtgcgccc tgccggtgga acggctggcg tccaaagact
    30961 gcctgctgtt tttgtgggcc acattcccca tgctgccgga agctctgcgg ttaatcaaag
    31021 cgtggggctt ttcattcaag accgtggctt ttgtatggct gaaacagaac cgtaaaagcc
    31081 ttacatggtt ttacgggctg ggccgctgga caaggggaaa cgcggaaatc tgcctgctgg
    31141 caacacacgg caagccgaag cgtcgttctg cctctgtcca tcagtttatt atcagcccga
    31201 ttgaacaaca cagcaaaaag ccggatgtga cccgtgaaaa aatcgtagag ctggcgggcg
    31261 atttgccccg cgtggagctg tttgccagac agaaaacccc cggctgggac gtgtggggga
    31321 acgaggtgga atgtgacctt atcctgacgt gaaaggaggt gccaaatggc ttatgtaacc
    31381 gtccccaagg acttaaccca tgtgaaaagc aaggttgtgt ttgggcttac caaacggcaa
    31441 ctgatctgtt tttccggggc gctggtgatc ggcgtcccct tatattttct cacccgtgac
    31501 tatcttacca acagcgcggc ggccctgctc atggtatttg ccatgctgcc gggctttttg
    31561 cttgccatgt acgagcgtca cggccagccc cttgaagtgg tgattatgca gatcatccag
    31621 tgctgcttca tccagccaaa ggagcgtccc tatcagaccg acaacaccta caccgccctt
    31681 gtgcggcaat accagatgga acaggaggta aaggccattg tccaaaaagg aaatcccaag
    31741 agaaaccgaa aaaacaaagc tgacccgcgc ccagcgaaaa gaaattgacg cggtaatccg
    31801 taaatataag ggcgacggca ggccccacac ggcgcagcag agcatcccct acgaggtcat
    31861 gtacccggac ggcgtgtgcc gggtatcgcc cggcgtcttt tccaagtgca ttgagtttgc
    31921 ggacatcagc tatcagcttg cccagccgga cacgcagacg gctatctttg aaaaactgtg
    31981 cgacctgtat aactatgtgg acgcctccat tcatatccag ttttctttcc tcaatcggaa
    32041 agttgacccg gtgcagtacg ccaagagctt tgagatcgcg ccgcaggggg acgacttcga
    32101 cgacatccgg gccgagtaca ccggcattct gcaaaagcag cttgcaaacg gcaacaacgg
    32161 catggtaaag accaaatacc tgacattcac catcgaggcc gaaagcgtga aagcggcgcg
    32221 agccagattg aagcgcatcg gctttgacct gttaggctat ttcaagagca tgggggccgt
    32281 agcccatgtg atggacggct gggaacggct gaacctgctg catggcgtgt accacccgga
    32341 cggcgagata ttcaattttg actggaagtg gctggccccg tccggcctct ccaccaagga
    32401 ttttattgcc ccgtcctccc tgtgcttcgg caatgcaaag acattcggca tgggcggcaa
    32461 atacggcgcg gtaagtttcc tgcaaatcct gtccccggag ctgtcggacg atatgctggc
    32521 cgacttcctc aatacggaaa gcggtgtttt agtcaatctc catgtgcagg ccattgaaca
    32581 gaccaaggcg atcaagacca tcaagcgcaa aattaccgac cttgacgcta tgaagattgc
    32641 ggagcagaaa aaggccgtcc gcagcggtta cgatatggac attcttccca gcgaccttgc
    32701 cacctacggc gaggacgcca agaagctgct gacaaagttg cagacccgca atgaacggct
    32761 gttccagttg acgttccttg tcctcaacgt ggccgacacc aagcaaaagc tgaataacga
    32821 cgtgttccaa gccgcaggcg tggcccaaaa gcataactgt ccccttgtcc ggctggacta
    32881 ccagcaggaa cagggccttg caagcagcct gccgctgggc gtcaatcaga tcaagataca
    32941 gcgcagcctt acgacttcca gcgtggccgt gttcgtcccc tttgtgacgc aggagctttt
    33001 tcagggcggc gcggccatgt attacggcat caacgccaag tcccgcaaca tgattatgct
    33061 ggacaggaag caggcccgtt gccccaatgc cttgaagctc ggcacccccg gcagcggcaa
    33121 atccatgagc tgtaaatccg agatcgtcag tgtgttctta acgacgcctg acgatatttt
    33181 tatttcagac ccggaggccg aatattaccc ccttgtcaaa cggctccacg gacaggtaat
    33241 ccggctgtcg cctaccagca aggactttgt gaacccgctg gacatcaacc tgaattattc
    33301 ggaggacgat aacccgctgg ccctgaaatc cgactttgtg ctgtcgttct gtgagcttgt
    33361 catgggcggc aagaacgggc tggaagccat tgaaaagacc gtgatagacc gggctgtgcg
    33421 cgtgatctac cggccctatc tggcagaccc ccgcccggag aatatgccga tcctgtccga
    33481 cctccacaaa gcgttgttag atcagcatgt cccggaggct gaccgggtgg cgcaggccct
    33541 tgacctgtat gtgtccggct ccctgaacgt atttaaccac cgtaccaacg tggacatcgg
    33601 caaccggctt gtgtcctttg acattaagga gctgggcaag cagctcaaaa agctggggat
    33661 gctcattgtc caagaccaga tatgggggcg cgtcacggcc aaccgaagcc aaggaaaggc
    33721 cacatggtat tttgccgacg agttccattt gcttttgaaa gaggaacaga cggcggccta
    33781 ttctgcggag atttggaagc ggtttaggaa atggggcggc attccaacag gtgccaccca
    33841 gaacgtcaaa gacctgcttt cctccccgga aattgaaaat atccttgaaa acagcgactt
    33901 cattacgctg ctcaatcagg cgtccgggga tagaaaaatc cttgcggaac gcttgaattt
    33961 gtccaccgaa cagcagaagt acatcgacaa ttccgaaccc ggcgagggcc ttttgatctt
    34021 tgaaaacgtg gtgctgccct ttaccaaccc catcccgcac aacacccagc tttacaagat
    34081 tatgacgacc cgcttaaacg aggtggcggg agtatgaccc ggcgacgcca caaaggaggt
    34141 gaaccaccat gaaagagctg aaagccaagg cgaaagtgac gcaggccatg acccgcgacg
    34201 ggctgacgct ggaaaatcag gccaccggcg aggtggagaa catttccagc cgggaggccg
    34261 aacaggattt gtccgcgccg gggccgggcg gcaccgccga taagctgctg gaacgggccg
    34321 acgccatcca tgacggccat aaggccaaga aagccgcgaa gcaggccggg gctgtggccg
    34381 ccgaggggga cgctgccctg caccggccat ccgcccggct ccaactgtcg gaggaagaac
    34441 gggccgaccc ggatttacag ccctatatcc gaaaatcgga caaacgggcc gataagctgg
    34501 ataaggcccg cgccgccatc cccaagaagc gcgtcccggt caaggaaacc gtctttgacg
    34561 aggcaagcgg caaagcaaag accgtcctgc actttgacaa acaggacaag gggcctccct
    34621 ccctgaaacc caatccggca ggccgtcctg tttccgaggt ttttctattc ggccacggga
    34681 aaatccatga agtcgagcat gaaaacgtgg gtgtggaggg cggccataag ggggaggaac
    34741 ttgccgagcg gcaggccgga aaagccatcc gcagcaccat ccggcaccac aggctgaaac
    34801 cctactggga cgcggaaaag gccgagcgca ggctattgtc tgccaacgcg gagtatttct
    34861 accagaaatc tttgcgggat aacccggaga tcgcacaggc ggccagcaac cccatttccc
    34921 ggttctggca gaaacagcag atcaagcgcc agtacgccaa ggccgcccgg acagcgggcc
    34981 agaccgcagg cgcggcggca cagggcgcgg ccaagacagc cggggcctcc acgaaagcgg
    35041 ccaaggccgc agccaaagaa agtgaacggg cggcctcctt tgtggcccgc cactggaaag
    35101 gggcgctggc cgtccttgtg ttggggcttt tgatgctgct tatcatcggc ggcttacagt
    35161 cctgcaccgc catgttcggc agcgccggaa gcggcatcac ggcgtcctct tacttttccg
    35221 aggatagcga tatgttggcc gccgaggacg cctacgcgga gctggaagcc gagctgcaag
    35281 actatctgga caactacgag gccacccatg actatgacga ataccatttt gaccttgacg
    35341 agatcagcca tgacccctat gtgctgattt ccattctgtc ggcgctccat gacgggatat
    35401 ttaccatcgg ggaggtacag ggtgatttgt ccatgctctt tgacaagcaa tatatcctga
    35461 cagaaaacgt cgtggtagaa acccgttacc gcaccgaaac cgatacatgg acggacgcgg
    35521 agggcaacac ccatacagac acctaccaag tgccgtatga ctattacatc tgctacgtca
    35581 cgctggaaaa cttcgacctg tcccatgtgc cagtctatat catggacgag gaaacgctaa
    35641 gtttctattc cctgtatatg tccacgctag gaaaccggcc tgatctgttt tccggcagcc
    35701 agtaccccaa cgcctccacc ctgacgccgc cgacctacta cgacgtaccc ccggaggctt
    35761 tggaggatgc cacctttgcc gccatgctca aagaggcgga aaaatatatc ggttatccct
    35821 atgtgtgggg cggcagctct cccagcacca gctttgattg cagcggcttc atttcgtggg
    35881 taatcaatca tagtggatgg aacgtgggac ggctgggggc gcagggccta tataacatct
    35941 gcacccctgt ttccagttcg caggccaagc ccggcgacct tgtatttttc aagggaacct
    36001 acgacacccc cggcgtgtcc cacgtcggcc tgtatgtggg caacaatgtg atgctgcatt
    36061 gcgggaaccc gatttcctac acgaacctta cttcaaacta ctggcaatcc catttttaca
    36121 gttacgggcg tttaccttaa cgccagaaag gagctttcaa ttatggcaac caaacttgac
    36181 cgcatcgaaa aggacatcca gaaaaccaag tctaagatcg cggagtttca gaaacagctt
    36241 cgggagctgg aaacgcagaa aaccgaacag gagaatttgc agatcatcca gcttgtgcgc
    36301 ggcatgaaca tgaagccgga ggaatttgcc gcgttcttac gcagcggcgc aatgcaggcc
    36361 gcccctgccg caacccctta ccatgaacag gaggacaatg cccatgaaga ataagaccag
    36421 acggatttcc cgtattctcc ccgcacttct ggccgtgatg ctctgcgtca cggcctttcc
    36481 cgttaccgcc cttgcaggcg gcaatgaccc ggcaccggcc ccgctgccgg aggctacaac
    36541 cgaacccgct acgggcggtt tggagcctga aacagacgaa accggcaccg ccacggacgg
    36601 gacagaaacc gaggccgaaa aagataccgg ccctctgacc ggcaaggaca tcaccgacct
    36661 gttttccgcg ctgttcggtt ccaaggtgag cattgccgcc acggacgacg gcatccagat
    36721 caccaccggc accgacaaaa aagaacctga acagaccggc accgtcacca ccaacggcgg
    36781 caggctgaat gtccgcaccg gcgcggggct tgacaagacc gcgttcaccc agcttcccaa
    36841 tgggacgacg gttgaggtag tcggcacaga cggcgactgg attaaaattc tcttgccgga
    36901 gcgcatcggc tatgtccatt ccgactatat gaccgtcagc gaaaaggaag tagcggctac
    36961 cggcgagggc ggtttttccc tctccattga cccggaggaa attgcttctc tgctggaact
    37021 gttcaatggc ggcggggcca gcgccgccct gtccccggac gggaacctgt cactgattga
    37081 cgacatcggc agcgccgcga aaaatggcaa gcagtttatc accgtggaaa ccaaaaacgg
    37141 caatgtgttt tatctgatta ttgaccggga cgacgaggga aaagaaactg tccatttctt
    37201 aaatcaggtg gatgaagccg atctgctgac gctgatggag gacggggaaa ccgtcacccc
    37261 cgctgctgtc tgctcctgta ccacgaaatg caaggccggg gctgtgaaca cgaattgccc
    37321 ggtatgtaaa accaacctga ccgagtgcag cggcccggag ccgcaggaac cccagccgga
    37381 ggaacccgaa gccccggagg aagaacccaa gggcggcgcg ggcggcctga tcgtgttcct
    37441 gctggtggcg ctggcgggcg gcggtgcggc cctttactat ttcaagttca aaaagcccaa
    37501 ggctgaaacc accggcagcg acgatttggg cgagtatgat tttggggagg acgaggattt
    37561 ggaggacgag gaacccgaaa ccgagtttga cccggaagct gattttgtga gtgaacagga
    37621 ggacgaggaa tgacatataa acttgtaatc gcggaaaaac ccagcgtggc ccgcagcatt
    37681 gcgggcgtga tcggggccac ggagaaacac gacggctatt tggaggggaa cggctatctg
    37741 gtgagctggt gcatcggaca tctggtgtcc tttgccgacg ccggacgcta tgacgagcgt
    37801 ttcaaaaaat ggcgctatga ggatttgccc attctcccgg aaacatggca gtacatcgtc
    37861 cccgacgaca agaaacagca gtttgacgtt ctctgttcgc tgatgcagcg ccccgacgtg
    37921 accggccttg tgtgcgccac cgacgccggg cgcgaggggg aattgatttt ccgtttcgtc
    37981 taccagatgg cgggatgcca aaagcccttt gagcgccttt ggatttcctc tatggaggac
    38041 agtgctatta aggacggctt tgcccacctg aaaccgggcg gcgactatga tccgctgtat
    38101 caatcggccc tgtgccgggc caaggccgac tggctgatcg gcattaacgc cacccggctt
    38161 ttttccgtcc tgtaccacaa gaacctgact gtgggccgcg tccagacgcc gaccttaaaa
    38221 atgctggtgg acagggacgc caagattacc gatttcaaga aagagaaata tcacatcgtc
    38281 catatcacgg cgggcggcgc ggacgcggta agcagccgct tttccgacgc tgccgaggca
    38341 aacaccgtca aggcggcttg tgcaaaagcg caggccgttt gcgtttccgt gacgcgggag
    38401 aaaaagacgg aacagccgcc caagctctat gaccttacca ccttgcagcg ggaggctaac
    38461 cggcttttcg gctataccgc caagcagacc cttgactatg cccaggcact gtatctaaag
    38521 aagctgctga cctatccgag aacggatagt caatatctta ccgacgatat gctgcccgcc
    38581 gtggaaagcc ttgtgtccgg cctgtgggag ctggtgccgt ttgccaaggg cctgaacctt
    38641 tccccgcagt ttgaccgcat cctgaacagc aaaaaggtgt ccgaccacca cgccattatc
    38701 cccaccgctg aatttgtgaa gcagggcttt ggcactctgg ccgagagtga aaaaaagctg
    38761 ctgtccctga tctgctgcaa gctcttatgt gccgtggccg ggccgcatat ctatgaggcc
    38821 gtcaccgcca catttacctg tgccgggcag gagtttaccg ccaagggcaa gaccgtcctt
    38881 tcccccggct ggaaagagat tgaacgccgg ttccgttctt ccttaaagac cgacgccgac
    38941 gaggacgccg aggcggtgcg ggagctgccg gagctttgcg agggccagac ctttgcagac
    39001 gtggccgcct ctgtcaccga gcatttcacc acgccgccca agccctacac cgaagatacg
    39061 cttttgtccg ctatggaacg ggccggggcc gaggatatgc cggaggatgc cgagcgcaag
    39121 ggattaggca caccggccac ccgcgccgcc attctggaaa agctggtgca gatgggcttt
    39181 gtccagagaa aaggcaagca gctcattccc accaaggacg gcatcaatct ggctgtggtg
    39241 ctgccggagg cgcttacttc tccccagctt actgccgaat gggaaaaccg gctgaccgag
    39301 atcgccaagg ggcaggccga tcctgacgaa tttatggacg gcatcgagac gcaggcgcgg
    39361 gagctggtgc agacctattc ctgtatcagt gaggaaaagc agaaattgtt tcaggccgag
    39421 cgtgttccta tcgggacgtg tccccgctgt ggtgaggctg tctatgaggg caagaaaaac
    39481 tactactgcg gaaaccgggc ctgccagttc gtcatgtgga agaatgaccg attttttgag
    39541 gaacgcaaga aagcgttcac cccgaagatc gccgctgcgc tgctcaaaac cggcaaagtc
    39601 aaggtaaagg gcctctattc cgtaaagacc ggcaaaacct acgacgggac ggtgcttttg
    39661 gctgataccg ggggcaagta cgtcaactac cgcattgaac acaggagcta aaggacagta
    39721 acacagcaag catagggagt gtggctacac tcccggtaaa atcccccggc cgcgtccctg
    39781 ccgggccggg gatttttgct tgttggggaa gtccccaacc ccctattttt tgaaacagaa
    39841 cagagaaagg agtgaccgcg tgaacgaagt attttctatc caagtccata accggcagtt
    39901 tttggaacag ggcaaacaag gcgtctggct ggatttgccc accacaaccg aaacgctgca
    39961 agccgccctg cgggatgttg gcattactgc cgacaatccg caggattttt ttatcaacgg
    40021 gtattcctgc ccggaggaca gacaccttgc cattccctat gacatggtgc tggccgccga
    40081 cgtggacgag ctgaatttcc ttgccgcccg gctgggccag cttgacgccg ccgagatcgc
    40141 agagctgaac gccgccctgc aaaatccccg tggcggcttt gagaatatcg gccagatcat
    40201 cgactacacc gaaaatgtgg attactatgt gcatcttccc gacgttaggg gggatggaca
    40261 gttgggcgac tactacctga accgttccgg catggtggat atgccggagg aatggaaagc
    40321 cgggattgat acggcgcagt ttggacgcca cattgcccag caggaacaag gcgtttttac
    40381 ccagtacggc tatctggtga gaagcggcga cgaatggcag cgcgtccatg agggccagcc
    40441 ggtgccggag gaataccggg tgatgcacta cccccagccg gaagctgacc gggaggaacc
    40501 gcaggcccag cagccggagg catccgaaag ccccgacaaa gcgccgcccc cggttatccc
    40561 gatcatgctg gacggcatga acagcaaaga acgcatgaaa gtgattactg accgtctgga
    40621 aaccggcgta caggagcttt ttgaaagtag ccgctatatg gcttacttat ccgctatgtc
    40681 caagatgcac gattacagtc tgaacaatac gctgctgatc gccatgcagg gcggttcgat
    40741 tgtggcgggc tataacaggt ggcaggatga atttgaccgc catgtgaagc ggggcgagaa
    40801 aggcattaag atactggccc cggccccgtt caaggttaag cagcagatgg agaaaaccga
    40861 cccggccacc cagcagcccg tgatcggcgc ggacggcaag cccgtgaccg aagaacagga
    40921 agtgacggtt ccggccttta aggtggtgac agtctttgac atcagccaga ccgagggcaa
    40981 ggattttccc atgccctata tcagtgaact taccggcgac gtgcagcagt atcaggattt
    41041 ctttgccgcg ctggaacgga catcacccta tcccataagc attgagccga tttcagacgg
    41101 ggccaagggc cgctgcttct acgcaaaaca gcgcattgcc atcaacgagg gcatgagcga
    41161 attgcagacc ctaaagaccg ccatccatga gattgcccat gccaagctcc acgccattga
    41221 ccgggaggcc cccgccgagg aacaggcggc ccggccagac cgcagcaccc gcgaggtaca
    41281 ggccgaaagc gtggcctata ccgtctgcca gtattacggg ctggacacgt cggactattc
    41341 ttttggctat gtggccgatt ggagcagcgg cagggagtta tccgagctga aagcctccct
    41401 tgaaaccatc cgggccacgg ccagcgaatt gataaccgag atcgacggcc attttgccca
    41461 gcttcagcag gagcgcgagg cccggcagga acaggaggcc gtcacggttg acgttacccc
    41521 ggaggcagcg gccccggcgc aggccgagga agaacaggcc ccggcccttg atccggcagc
    41581 cgagccgctt gtgactgtgc tatggagcga aagcccccag ctaaaggacg gccagcaaat
    41641 gccgttgcat gaggccgacg cgctgtttgc ccgtctggat gcagcatatc cggcagaggc
    41701 aggctatgac aaaaccgcgt tccgcattga ctgtatcttt cagggcgagc cggacagcta
    41761 cgaggggcgg caggattttg gagataggga cggttccctg atcgaacata tccagagcta
    41821 ccaccaattt tacgcgcagg acgaaaactg gaaaaagcat gtaatcgcta caaccggcat
    41881 agagggctgg gagcaggaca aggcccatcg ggatatgctg ttaggcgagt ttgtccccta
    41941 tatgaagctg cattgcagcc ttgcccaaat ggaacagacg gcgcagggcc gcttacagtc
    42001 cggggaaacc ctgacgccgg aggaaacggc ctatttgggg gcgcttctct cttatgtgca
    42061 ggagtgccgc cccatgctca atcagggcca gtatcagttg ccggagccgc cgaaactggc
    42121 tgacttcgac cagagcttgc aggactacaa agcacaggta caggccgaga tcgcgcagga
    42181 ggccgccgca gccggtatga ccgtggagga atacgcggcg gctggctatg aagcacccca
    42241 acaggacacc ttttccatct accagcttcg aggcggggag gaaacccgcg actatcggtt
    42301 tgagccatac gagcgtttac aggccgcagg gctggccgtg gacagtgcca actatgacct
    42361 tgtttatacg gcaccgctgg ataaaagcac gtctttggag gatatttacc gcacattcaa
    42421 catcgaccac ccggcagatt ttaggggaca cagcctttcc gtttccgacg tggtggtgct
    42481 gcaccagaat ggacaggaca ccgcccacta tgtagacagc ttcggctata tggaagtgcc
    42541 ggagtttttg cgggaaaatc ccctgcgtac cgccgaactg tctacggagc agaacgaaaa
    42601 catgattgac ggcattatca acaatacgcc gcccgaaccg cagccggagg aacccgaaca
    42661 gctatctttt gaggatgtgg cagttgcttc cggccagaca caggaggaac ccccggaggc
    42721 tgcgcccccg caaacggctg tccgctatta tcccatcaat gagggagccg cccgccgcgc
    42781 caaggaagcc atgagctttt ctgactaccg gcccggcagc gccacggcgg aataccggca
    42841 ctatgtcgat caggccgtgg aaattgcgga gcgccagaaa aagcgtgtgg agccagagta
    42901 tcacgaaaag atagacagcc tccttgacac ctacgcccgc aagctggccg agaacatgaa
    42961 taagggctat gagattaccg cccgcgtccc ctctgtcctg attgccgggc cgtccaattt
    43021 cccggtacgg gcgaaagaaa agcagaacgc cgccagtgac cgcaacatgg aggaatttca
    43081 gtacattcag ggcttgcttg acaaaatccg cagcaccggc atgggtggta tcagcgccga
    43141 cgatccgcag gccgtttcca agctggaaaa gaaactggaa aagctggaag cgtcgcagga
    43201 gttgatgaag gccgtcaatg cctactaccg caagcatggg acgctggacg gatgccccca
    43261 tctgatcgaa agaggcattg aaaacctgaa agcggatatg gcgtcgggct ggcactatga
    43321 gaaaaaaccg ttccagtcct ggcagctctc caacaataac gccgagatac gccggttaaa
    43381 gggccgcatt gaggaattga cccgccaaaa ggaggcggcc tatgtgggat gggagtttga
    43441 cggcggcact gtggagatca accgggtggc caaccgcctg caaatcttct ttgaggggaa
    43501 gccggatgct gctgtacgcg acgagctgaa aagcaacggt ttccgctggt cgcccaaggc
    43561 cggggcatgg cagcggcagt taaacgacac cacaatccgc gtcgctgacc gtatcaagtg
    43621 catccagccc ctttccggcg aaaagcccag cgccttacag cttgcggccc gcagggagaa
    43681 agaaaagccc tctatccggg cgcagctcaa cgcggccaag accgaacagg ccaagcagcc
    43741 accggcgcgg gaaaaatcaa agggattgga ggtagagtaa atgcagaagt ttgaaaatgt
    43801 ggacgttctg gccgcgctgg aacagatcat gcggcagaac accgcgtttt atcaaagtga
    43861 ctttggcatt gacaaagaca ttatcaggcg ggatgccgcc agcgatcagg ccgcagacaa
    43921 gaccctgctc tggatgtccc ggccctccgg gacgtactgt ttccgggaac gtgatgtttt
    43981 cctgaaagac acccgacagt acaacacatg gaaattttac ggggagcaga cccgtgacaa
    44041 gatactggcc tacgcggtgg agctgaccgg cacacagggc ggcactatcc ggggcaatct
    44101 ctatgagctg gactatccgc agcatttccg gcacgtcatt gaaaccgccc agccggtgag
    44161 tgtgaaccgg ctcttttatg agcatggcac ccgtgacatc ccggagagcc agcgttttga
    44221 cggaagccct gaccgggtat tgggaaactt tttgtactat gaggcccagc cccatgaccc
    44281 ggctgtgctg caggaggcgc tacggacgga gcagcacagc cgggggcggg ccgtccccgg
    44341 cgatttcaaa gtccacgtca ccgctttgca tgacagccgg attgaaaccg aggcccggcg
    44401 tattgtggac agcctgaaag atctgtccgc gcctaacagc cccaataaaa cgcatttcat
    44461 ggtggagatc tccccgcact ttgcggcgat tgcttccacc aaggataatg accggctctt
    44521 tgccatgctg ccctataaat ccctgtgttt taccgggatg aaaggcaggc atggcgtgta
    44581 tgccgtgatt aaccgggacg agcgccggga tgtgagtatt cgcaggcccc ggccctctat
    44641 ccgcaagcag ctatccgaca gcaaacaggc cgccagccca aaaaaggcgg cggccagaac
    44701 caaaaagaat gaattggagg tataaggaat gatgcacttt accgtggagg aagaaaacct
    44761 gatctgtatg taccacaatg cagaccggcg cagaacgata aacaggctca ccgccgtcat
    44821 gccggttatg gatggggata tgcgggcgca ggcccagcag accctttcca agctggaacg
    44881 catgacggat gccgactatg acggccagaa gttccacttc acagacgaat aacgaacagc
    44941 agacgccggg cgcggcggcc atgtggtcgc ttgcgtccgg cgtcttttct ttttgcctat
    45001 tcctacgcat ttagaacccg gtattgtcgg ggataggatg aagtattcgc ttgcccctgc
    45061 aaacatgcgg gagaagcctt gcagcgggcg gttttcaatc ccttaaatgc gtaggttgca
    45121 gctataatta gacccctgaa acagatatag ccgcgcagcg ggtgtatctg tttcaggggt
    45181 gtgcaggtga tagccgcaaa gcggcgtaag agggtgcagc cctcttgccg tctatctctg
    45241 ttccagcggg aagctcggca atgcttccag cagtttcagg gaaatgcgct gccgtatatc
    45301 ttcgtcaatg actttcttct ttttgccgtt tgcctgtctg atctccaccg tggaaagctc
    45361 gttgatgtag tcagcataat gggccaacac tttttccgtg gcccacctct caccggcaac
    45421 ggcggctttg atcgtttcat agtccagcag cttttcttgt ccgtccatcc tgataccccc
    45481 gtcagactga ttttttctat gataccatat tcggaagcat ggaaccagag aaaacggcgc
    45541 ttttctgctg gtaaattcta cgcatttaga acagcacttc ggcggggata ggataaaaca
    45601 cccacatacc ccgctgacca tgccggaaaa gccttgaaat ataagggctt ttacagctct
    45661 aagtgcgtag gtttccagta tcttttccgc tggcgctcgg cctctttgcg gcggcgcatc
    45721 cgtttggagc aggccgcgca gtatttggcc cggttagact tcggcgtgaa cgtggccccg
    45781 cactcacagc agcgtttcac ttcgtcccgg tctttggtga tctcggcata cagggccgca
    45841 tccagcggga ggacagcggc cttaaaccag cggcacagaa gcgaatagga aatgctctgt
    45901 acgcaaatac attcttcgcc gtcgtccagc aacaggcagt tgccgtcaca atagttgcag
    45961 cactcatgcg tcagcttccg ggccttgcga tattgagggt aattcattcg tggaatactc
    46021 atagctcttg cgtccattcc tttcccggcg tcatacgcaa aatgccgtcc acattctgct
    46081 tgatgatgcc gtattcctgc atctgctttt tcgcttcgcc gtacttctca tacagccgtt
    46141 ccttttcctc ggccaatcgc ttgtactcgg ctttcagggc gtacagatcg gggagctttt
    46201 tcacaccctg tccctttagg gcctttgccg cagcttcata caaaatcaac gtgctttcat
    46261 gctcacgccg gaattttgcc ttatccgctg cattgcggta ttccatagcc acgggccaga
    46321 gctgcttgta ggtagaaata ttctttatca gcaccgccat atccgcaagc cggtgttcca
    46381 tagctttgag ggtagcggcg gcctcgtcgc tggcggcggt gatctcggcc actttgcttt
    46441 ccaaatccgg gtaggtgtct atcccatgtt cagtcaggaa attcaaagtc tttgcggcct
    46501 gcttcaaatt gtggagcttc gcccacctct catagcctgc cgactgctgg gccttaatgt
    46561 tgttttccag atcaatccgc aaagaaatcc ccttgcgctc tttgggcgct ctggtgataa
    46621 cgcggccttt gatacgctct ttgatggctt cctcggtgta ggcttccccc aatgtcttgc
    46681 agcgggtaaa gcgttcctgt ccgggagcgc ggaaagaaat aaactttccc ggcttgatct
    46741 catagccctg cgcctgcatg agccgcagga aatcatcaaa atcttttgcc tgcgggatag
    46801 cggcgtcaat ggctgctttg agcttcgctt tccagctcgt ccctttccgc tgggcgtccc
    46861 actcggcata gctcttgccc ttactctggc cgggcttcac cacggacaat ccgttttcct
    46921 tgcacagcct gtcgctggtg cgccggatat aggcatagct ctgtttgttg gaaatgtact
    46981 tgcgctgatt taccatatcc acggcacaga aaataatgtg attgtggacg tggcccttat
    47041 caatatgggt agtcagcaca tagggatatt tcccttgcag cacttcctcg gcaagctgct
    47101 tcccgatctc atgggcctgt tccggcgtgg cttcgccggg ggcaaaggat tgtatcaggt
    47161 ggtggcccag attattgccc ttttggtatg cctgcgccag cagcatttca aattcaatgt
    47221 ccgctgtttc ataagagcag gcaaaggagg ccaccagcag cttgccgtca gttttgtccg
    47281 ggttctcgat gtagtcaagg gcttttttca gcgttgactt gataggatgt atctttgtaa
    47341 ctgccatatc tgcgccagcg ccccctttat atcctcgatg tcctgtgcgt acaccggccc
    47401 cataccgttc agcctctttg caatctgatt gacgttgacg ccgatcttct gtatctcggc
    47461 ggtctgcgcc cggatgtcgc tggtgtccat gttgacgata tagccgtcaa tgagcatctt
    47521 ccgggcgtag gctgaaaagt tcttcgtatg cagcagcgcc attttctgtt caatcatagc
    47581 ccgttcctcc ggcgtcacag ggacgcgcag cacgattttt cgctttctgt ttgccatgct
    47641 tcaccgtcct ttccattcag gggtttgggg atttccccaa caagcaaaac ggacgcggcc
    47701 cggcagggac ggggcaggcc gtttttccgg gagtggctac actccctatg cttgctacgt
    47761 tactgtttct ccactaacaa gacgtttcca aagccccaaa ctacccgcaa aatagccctc
    47821 tggaaagaaa aaagtgcaaa aaaatagaag ctacgctgtg cagctcccgc taaaagtaaa
    47881 acagaggatg ccagttacac atcctccgtt tcattcttct tcggcttttc aattagtatg
    47941 gcgctgtcaa tcgcgccctc gatgatcggc aggtattctt cggggcagag tttcagcttg
    48001 tggctgaccc tttgccgcag ttcgctttcc tcccgcatga tctccgggtt aaagtagcgt
    48061 tccacaggaa gcccgcaggc tttaataagc tgtatgacaa ccggcagact gggaatggcc
    48121 cgtcgttttc gatgttggca agatagcgcc agtcaatatt tattttctct gccattgctt
    48181 tgcgcgaaac gcgctttgct tgccgggccg ctttcacatc cgcgccgaaa gtttcaaagc
    48241 cgggacaatc ttcaatattc gccatatcgc acctcccact tacattgtat atttcatact
    48301 ctgcccgtgg aatgttggta tatgcacctt tcttaaagtt tatatttcac attttgtttc
    48361 ttttattctt cgagcaaaag aattataatg taccctgtgg aggtgtacta tggactacat
    48421 gacgttgaaa gaggcaggcg agaaatgggg tgtgccccca cgatggataa actactattg
    48481 tgctgcggga cgcatccccg gcgctgtaaa gatggcgacg atctggctca ttcccaaaac
    48541 tgcggaaaag ccgattgaca ggcgtacaaa gaaaggaaag gcggttactg aatagtataa
    48601 tgaaaccggc gcattttgga tatggttttg aagagagaga aagcatggta ttttgtcacg
    48661 gaaaaactat aagatgatag atggcaggct gctccagacc gataaaaagt attctcatct
    48721 gaaacagaaa gaaaagattt acacatggat gtatgaagaa gcgaaacttt atcatgacag
    48781 aaatggaaaa tgcccgaaac aaagacgagg aagctgctgc tgtatcagcc gtatatggta
    48841 gaattgaaaa ggccggcatc tggattcttt atggtgaagt ctccagacat tggataactg
    48901 ctggtctaat gcgcctttga gtatggggtg attgatttta ataccgggga ggtacggctt
    48961 tttgaggaaa atattctggg atttacattt ggcgattatt acatttcctg taactgcaag
    49021 gacacggatg atgaagatat gaggaatata gacttgctga ttttctactg tcttgaacgg
    49081 tattaggact gaatctgctg cgcggagtgc ggcaagagcg accggaggga gtacacacag
    49141 gccctgcctg tgtgaaaagc cataccgcaa ggtgcattcg caaaaaagag gccgcgcatt
    49201 ttgctgaggc ttggggtgtc cccaacaagc aaaacgagaa cgccgcaggc gggcaagtgg
    49261 tggatcagaa tatccgtaaa ggatattctg atccattgct tgccagtatt atcgggatgt
    49321 tttgacaacc gctgtaatcg aaacatccca aacattaaga aggtgttaat tattattatc
    49381 ttgatttaat tcgtttaaac caataatata gatacataca ccatgaaaag aagcgagtat
    49441 cccaatgacg gatgattaaa atccgaaaag aaatcgcttt gaaactacag ggaaactaca
    49501 gactgttatg ttatcttctt aaaatggagg gatttttatg tcgatacgaa ttctacttgt
    49561 cgaggatgat gatcatatct gtaatacagt aagggcgttt ctggctgagg caggatatca
    49621 ggtggatgcc tgcacagatg gaaatgaggc atacaccaag ttttacgaaa acacttatca
    49681 actggttatt cttgatatta tgctgcccgg tatgaacggg catgaacttt tgcgtgaatt
    49741 tcgtgcgaaa aatgatactc ccattctgat gatgacagcc ctgtcggatg acgaaaacca
    49801 aatccgggcg tttgatgcag aggcagacga ctatgtaaca aagccattca agatgcagat
    49861 tttactaaag cgggtggaag ccctgctgcg gcgcagcggt gcgctggcaa aggaaatccg
    49921 tgtcggcagg ctgacacttc tgccggagga tttcacggta ctttgtgacg gtacagagct
    49981 gcccctgaca cgaaaagaat ttgaaatcct tttgctgctg gtgcagaaca aaggcagaac
    50041 cttaacgcat gaaatcattt tgtcacgtat atggggatat gactttgagg gtgatggcag
    50101 cacagtccac actcatatca aaaatttgcg ggccaagctg ccggaaaata tcatcaaaac
    50161 cattcgcggt gtaggatacc gattggagga atcataataa tggaaagaaa agggattttc
    50221 attaaggttt tttcctatac gatcattgtc ctgctactgc ttgtcggtgt aacagcaaca
    50281 ctgtttgcac agcaatttgt gtcttatttc agagtgatgg aattacagca aacagtaaaa
    50341 tcctatcagc cattggtgga actgattcag aatagcgata ggcttgatat tcaagaggtg
    50401 gcagggctgt ttcactacaa taaccaatcc tttgagtttt atattgaaga taaagaggga
    50461 agcgtactct atgccacacc aaatgccaat acatcaaata gttttagacc caactttctt
    50521 tatgtggtac atagagatga taatatttcg attgttgctc aaagcaaggc aggtgtggga
    50581 ttgctttatc aagggctgac aattcgggga attgttatga ttgcgataat ggttgtattc
    50641 agccttttat gcgcgtatat ctttgcgcgg caaatgacaa cgccgatcaa agccttagcg
    50701 gacagtgcga ataaaatggc aaacctgaaa gatgtaccgc cgccgctgga gcgaaaggat
    50761 gagcttggcg cactggctca tgatatgcat tccatgtatg tcaggctgaa agaaaccatc
    50821 gcaaggctgg aggatgaaat cgcaagggaa catgagttgg aggaaacaca gcgatatttc
    50881 tttgcggcag cttctcatga gctaaaaacg cccatcgcgg ctacaagcgt tctgttggag
    50941 ggaatgcttg aaaatatcgg tgactacaaa gatcattcta agtatctgcg cgaatgcatc
    51001 aaaatgatgg ataggcaggg caaaatcatt tccgaaatac tggagcttgt cagcctgaat
    51061 gatgggagaa tcgtacccat agctgaaccg ttggacatag ggcgcacggt tgccgagttg
    51121 ctgcccgatt ttcaaacctt ggcagaggca aacaaccagc ggttcgtcac agatattcca
    51181 gccgggcaaa ttgtcctgtc cgatccgagg ctgctccaaa aggcactatc caatgtcata
    51241 ttgaatgcag ttcagaacac gccgcaggga ggcgaggtac ggatatggag tgagcctggt
    51301 gctgaaaaat gccgcctttt tgttttgaac atgggcgttc acattgatga tactgcgctt
    51361 ccaaggctgt tcaccccatt ctatcgcatt gatcaggcgc gaagcagaaa aagtgggcga
    51421 agcagaaaaa gtgggcgaag cggtttagga cttgccatcg tacaaaaaac gctggatgcc
    51481 atgagcctcc agtatgcgct ggaaaacacc tcggatggcg ttttgttctg gctggattta
    51541 ccgctcacat caacattgta aatatttaaa acttaaatga ttttgggctc tttgtcaaat
    51601 aggactgata gagtgagata agaacatcta aggtagaatt ccttttctac tttagatgtt
    51661 ttttgattca taggtaatca gattatttag taagaaaatt ctggtcttca ttttccgaaa
    51721 gcttcgaaag ccataagcga ctcgtttcaa tgctttgatg tgggtatgca gattttctat
    51781 tttggcattt gaataaggca attcgagggc taaacgaatg ccggattcat agtttataaa
    51841 agcttttttt atagaatgca gttcttttgg aacggaattg ggcatcgttc ttacaagttt
    51901 aaagaaagtg tccgcctctt tgtcgtgaaa cgcttgaaga atttcttgat agtaaaaata
    51961 ggcgattcgt aattcgtcag agatcgaaag cagacgatcc accacttcac tttcggtgag
    52021 atacgcccaa ccaaaattgc gccatttggt ccatttgtca taaacaagct tgtcctgtcg
    52081 tttgatcaga agccgagaca acgcctttaa ttgtcgataa tatttggctt gtgttggatc
    52141 gtttcgatca aagcttttca tgattcgtac gcgaatatcc tcaaatttac gaatgagatg
    52201 tttgacaatg tgaaaacgat ccacaacgag ttttgccttt ggaaaacatt cctttatcag
    52261 agaggcataa gaaacattca tgtccgtcac gatgaccttt accttcaatc gtgcgcgtcg
    52321 ttcaaattgc ataaaataag aaacgagagc ctttttcttc cgtgaaggaa gaatatccag
    52381 taattttcca gtatcgccat ccatacaaga aaaggagtag ggaccgactt gatttttcag
    52441 tgaacgaaat tcatccatta ataaacaacg cggtaaccaa tttcttttta cttttgtcat
    52501 ggggatcaga gaagcgagtg tccgagaaac ggtcgaccaa gaaacgccgc aatgcttagc
    52561 aattgtcgtc attgcttgtt tttcagttag ctcttctaaa attttatagc gcacttgttt
    52621 agcgataaag cagtttctat cgacaatgta ggtattcgcc gtaaaatagg tgtggcagcc
    52681 acgacagtgg tagcgttgtt tcgctaaagc aagataagtc agttggttcg cacatttatt
    52741 aagttgaatg agcgattttt tctttccgtt cttaacgatc atgccttcat gattcatctg
    52801 tttacacaaa ggacagcgac gaatttcttt acttaacgtc gcagaaacaa caagactctt
    52861 gatattctta atgctcttcg attccacatt tgtgatgaaa atgtttttat ctttgattcc
    52921 aagtagtagt ttgatatgat gaagatcagg catacagaac gctcctttga ttgtgttgtg
    52981 gtgattcaat tctaacggag cttctgtatg ttttgttttt tcatgctcaa aagggaccga
    53041 tagaatgatt ttctatcagt cctagaaatt atagagccga ttttgaccga caggtataac
    53101 cctgccggtc tttttttgct gctacaggaa aactacagac tggctacagg gaaagtacag
    53161 atgcgcttgc cataataaca atcgtaccag ccacaaatcg tagttttatt gcaaaggagg
    53221 cattcgatca aatggaaaaa agcaactatc attccaatgc ggatcatcac aaacggcata
    53281 tgaaacaatc cgtggaaaag cgggcttttc tatgtgcgtt cattatttcg ttcacagtct
    53341 gcacgctgtt tttggggtgg agactggctt ccgtattgga ggcaacacag ataccgccca
    53401 tccctgcaac tcatacaggc agcagcactg acgtagtgga gaatttggag gaaaacgctc
    53461 ttgccaccgc caaagaacag ggagatgaac aggaatggag cctgatttta gtgaacaggc
    53521 agaaccccat ccccgcacag tacgatgtgg agcttgagca actatcaaat ggtgagcgga
    53581 tagatattcg gatttctccc tatcttcaag atttgtttga tgccgcaaga actgatggag
    53641 tttacccgat tgtcgcatcc ggataccgaa caacagaaaa acagcaagaa attatggatg
    53701 aaaaaattgc cgaatataag gcgaaaggct acacctctgc acaggctaaa gcggaagcag
    53761 aaacttgggt ggccgtgccg ggaacgagcg agcatcagct tggtcttgct gtggatatca
    53821 atgcggacgg aattcattca acaggcaacg aggtttatag atggctggat gaaaacagct
    53881 atcgttttgg ttttattcgt cgctacccac cagacaagac agagataacc ggtgtgagca
    53941 acgagccgtg gcattaccga tatgttggca tcgaagctgc cacagagatg tacaaccaag
    54001 gggtttgcct tgaggaatat ttaaaaccag aaaaatgaga aaaggatgtt atgttatgga
    54061 cagaaaaaga ttgacacagc gtttcccgtt cctgcttcca atgagacggg cgcagagaaa
    54121 aatgtgcttt tatgcgggaa tgagatttga cggctgtcgc tatgcgcaga cgatagggga
    54181 aaaatcgctt tcccatttgc tctttgaaac ggattgcgca ttatacaacc acaataccgg
    54241 atttgacatg atataccagg aaaacaaggt gttcaactta aagctggcag caaagacctt
    54301 aaacggctta ttgataagac cgggggaaac cttttctttc tggttgttcc tgcatacgcc
    54361 attgacaatt atccagcgca gaggtcacga agtaaaggag tttccagagc caaacagtga
    54421 cgagattaaa ggggtggatg caaccatttc agagggctgg attgatttaa aagtgcgaaa
    54481 cgataccgac tgcacctacc aaatatgggt gaccttagat gatgagaaaa tcatcggtca
    54541 ggtgttcgcc gacaaagagc cccaagcatt atacaaaatt acaaatggca gtatccagta
    54601 tgtccgtgaa agtggcggga tttatgaata tgcccaggtt aaacggatgc aagttgcctt
    54661 aggtaccggg gaaataatag attgcaagct gctttataca aacaaatgca aaatctgtta
    54721 tcccctcccg gaaagtgtgg atattcagga ggagaaccaa tgagaaaaag tgtgggcatt
    54781 actgtttttg gatgcgaaca ggatgaggca aatgctttcc gcgctttatc gccggatttt
    54841 catattatcc ctacgctgat tagcgatgcg atatcggcag acaacgcaaa attggccgct
    54901 ggcaatcaat gcgttagcgt aagccataag tccgaggttt ccgaggcgac aattcttgcg
    54961 ctgagaaagg tcggggtaaa atacatttct acccgcagca tcggctgcga tcacattgat
    55021 acgactgccg ccgagagaat gggaatctcg gttggcacgg ttgcgtattc gccggacagc
    55081 gttgcggatt atgctttgat gctgatgctg atggccatac ggggtgcaaa acccaccatg
    55141 cacgccgtgg cgcaacaaga tttcagattg gatcgtatcc gggggaaaga actgggggat
    55201 atgactgtgg gagttattgg aaccggccat atcgggcaag cggtcgtcaa aaggctgcgg
    55261 ggatttggat gccatgtgct ggcctatgat aacagccgaa aaatggatgc agattatgtc
    55321 cagcttgatg agcttctaaa aaacagcgat attgttacgc tccatgtgcc gctttgtgcg
    55381 gatacccgcc atctgatcgg tcagaagcaa attggagaga tgaagcaagg cgcattttta
    55441 atcaacaccg ggcgcggagc gcttgtcgat accggggcgc tggtggaggc gttggaaagc
    55501 ggaaagctgg gtggtgcggc actggatgtg ttggagggcg aggatcagtt tgtttatacc
    55561 gattgctcgc agaaagtgct tgaccatccc tttttgtcgc agcttttaag gatgccgaat
    55621 gtgatcatca caccccatac ggcgtactac actgagcgtg tgctgcagga tactacagaa
    55681 aaaacaatca ggaattgtct caattttgaa aggagtttac agcatgaata gaataaaagt
    55741 cgcaatcatc ttcggcggtt gctcggagga acatgatgtg tcggtaaaag ccgcaataga
    55801 aattgctgcg aacattgata cggaaaaatt cgatccgcac tacatcggaa ttacaaaaaa
    55861 cggtgtatgg aagctatgca agaagccatg tacggaatgg gaagccgaca gtctccccgc
    55921 catactctcc ccggatagga aaacgcatgg gctgcttgtc atgaaagaaa gcgaatacga
    55981 aacacggcgt attgatgtgg ctttcccggt tttgcatggc aaatgcgggg aggatggtgc
    56041 gatacagggg ctgtttgtat tgtctggtat cccctatgtg ggctgtgata ttcaaagctc
    56101 cgcagcttgc atggacaaat cactggccta cattcttaca aaaaatgcgg gcatcgccgt
    56161 tcccgaattt caaatgattg ataaaggtga caagccggag gcgggtgcgc ttacctaccc
    56221 tgtctttgtg aagccggcac ggtcaggttc gtcctttggc gtaaccaaag taaacggtac
    56281 ggaagaactt aacgctgcga tagaagcggc aggacaatat gatggaaaaa tcttaattga
    56341 gcaagcgatt tcgggctgtg aggtcgggtg tgcggtcatg gggaacgagg atgatttgat
    56401 tgtcggcgaa gtggatcaaa tccggctgag ccacggtatc ttccgcatcc atcaggaaaa
    56461 cgagccggaa aaaggctcag aaaatgcgat gattacagtt cccgcagaca ttccggtcga
    56521 ggaacgaaat cgggtgcagg aaacggcaaa gaaagtatat cgggtgcttg gatgcagagg
    56581 gcttgcccgt gttgatcttt ttttgcagga ggatggcggc atcgttctaa atgaggtcaa
    56641 taccctgccc ggttttacat cgtacagccg ctacccacgt atgatggccg ccgcaggaat
    56701 cacgcttcct gcactgattg acagcctgat tacattggcg ttaaagaggt gataagtatg
    56761 gaaaatggtt ttttgttttt agatgaaatg ttgcatggcg tccgttggga tgccaagtac
    56821 gccacatggg ataacttcac aggaaaaccg gtggatgggt atgaggtgaa tcgcatcatc
    56881 ggcacaaagg ccgtggcgtt tgctctgcgc gaggcacaaa tccatgcggc tgcgcttggc
    56941 tatggcttgc ttttatggga tggatatcgg ccaagaactg cggtggactg cttcctgcgt
    57001 tgggcagcgc aaccggagga caatctcaca aaagaaaaat tttaccccaa tatagagcga
    57061 gccgagttga ttacaaaggg ttatgtggcc tcacaatcca gccatagccg tggaagcgca
    57121 attgatctta cgctctacca cctggataca ggggaacttg tttcaatggg aagtaacttc
    57181 gattttatgg acgaacggtc gcatcataca gcaaaaggga taggggatgc agaggcacaa
    57241 aatcgaagat gcttgcgtaa aatcatggaa agcagcggat ttcagtctta tcgctttgaa
    57301 tggtggcact ataagttgat tgatgagcca taccccgata cctattttaa ttttgccgtt
    57361 tcataatgaa agtattggtt ttgtatcaga ttttggattt gataaaatct atgctggtca
    57421 tggacaatct tttactggaa agtggttaaa gcatcttttg taatacattg caaattatag
    57481 tattcaatct gcccagcggc agaaaagaaa aaaaccgctg ttgggcagac ctttcccacg
    57541 cccattttgt attttgctgg cggcggtttt gagaaatcaa ggccgccgtt cttttctggc
    57601 agcaaaaggt gtggcggccc ataggaggat gccgctatgc tgttttgcta ttgccatgct
    57661 ctaatccact tccaccactc aaaaaaagcc ttgcccctc
//
LOCUS       DAFLWZ010000013        55872 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000013 DAFLWZ010000000
VERSION     DAFLWZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.013"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            320..640
                     /locus_tag="L1V38_000810"
     CDS             320..640
                     /locus_tag="L1V38_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBN1315380.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            794..1699
                     /locus_tag="L1V38_000811"
     CDS             794..1699
                     /locus_tag="L1V38_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315381.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1696..2469
                     /locus_tag="L1V38_000812"
     CDS             1696..2469
                     /locus_tag="L1V38_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1315382.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2650..4074)
                     /locus_tag="L1V38_000813"
     CDS             complement(2650..4074)
                     /locus_tag="L1V38_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1315383.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4285..4731
                     /gene="nrdI"
                     /locus_tag="L1V38_000814"
     CDS             4285..4731
                     /gene="nrdI"
                     /locus_tag="L1V38_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1315384.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4796..6778)
                     /locus_tag="L1V38_000815"
     CDS             complement(4796..6778)
                     /locus_tag="L1V38_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1315385.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6792..7688)
                     /gene="murQ"
                     /locus_tag="L1V38_000816"
     CDS             complement(6792..7688)
                     /gene="murQ"
                     /locus_tag="L1V38_000816"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1315386.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7691..8752)
                     /locus_tag="L1V38_000817"
     CDS             complement(7691..8752)
                     /locus_tag="L1V38_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1315387.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8963..9529)
                     /locus_tag="L1V38_000818"
     CDS             complement(8963..9529)
                     /locus_tag="L1V38_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1315388.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(9557..11059)
                     /gene="eat(A)"
                     /locus_tag="L1V38_000819"
     CDS             complement(9557..11059)
                     /gene="eat(A)"
                     /locus_tag="L1V38_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1315389.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11317..12438)
                     /locus_tag="L1V38_000820"
     CDS             complement(11317..12438)
                     /locus_tag="L1V38_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1315390.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12564..13505
                     /locus_tag="L1V38_000821"
     CDS             12564..13505
                     /locus_tag="L1V38_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1315391.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13655..14551)
                     /locus_tag="L1V38_000822"
     CDS             complement(13655..14551)
                     /locus_tag="L1V38_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1315392.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14820..16160
                     /locus_tag="L1V38_000823"
     CDS             14820..16160
                     /locus_tag="L1V38_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1315393.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16378..16821
                     /locus_tag="L1V38_000824"
     CDS             16378..16821
                     /locus_tag="L1V38_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBN1315394.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17325..18743)
                     /gene="nhaC"
                     /locus_tag="L1V38_000825"
     CDS             complement(17325..18743)
                     /gene="nhaC"
                     /locus_tag="L1V38_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1315395.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19146..20369)
                     /locus_tag="L1V38_000826"
     CDS             complement(19146..20369)
                     /locus_tag="L1V38_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBN1315396.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20400..21239)
                     /locus_tag="L1V38_000827"
     CDS             complement(20400..21239)
                     /locus_tag="L1V38_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1315397.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21256..21936)
                     /locus_tag="L1V38_000828"
     CDS             complement(21256..21936)
                     /locus_tag="L1V38_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315398.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21938..23011)
                     /locus_tag="L1V38_000829"
     CDS             complement(21938..23011)
                     /locus_tag="L1V38_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315399.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23067..23305)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23348..23581)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23658..24329)
                     /locus_tag="L1V38_000830"
     CDS             complement(23658..24329)
                     /locus_tag="L1V38_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1315400.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24416..27094)
                     /gene="mgtA"
                     /locus_tag="L1V38_000831"
     CDS             complement(24416..27094)
                     /gene="mgtA"
                     /locus_tag="L1V38_000831"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBN1315401.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            27753..28190
                     /gene="ndk"
                     /locus_tag="L1V38_000832"
     CDS             27753..28190
                     /gene="ndk"
                     /locus_tag="L1V38_000832"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBN1315402.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28212..29078)
                     /locus_tag="L1V38_000833"
     CDS             complement(28212..29078)
                     /locus_tag="L1V38_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1315403.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29238..31331)
                     /locus_tag="L1V38_000834"
     CDS             complement(29238..31331)
                     /locus_tag="L1V38_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1315404.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32080..32703)
                     /locus_tag="L1V38_000835"
     CDS             complement(32080..32703)
                     /locus_tag="L1V38_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315405.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32862..34259)
                     /locus_tag="L1V38_000836"
     CDS             complement(32862..34259)
                     /locus_tag="L1V38_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1315406.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34291..35262)
                     /locus_tag="L1V38_000837"
     CDS             complement(34291..35262)
                     /locus_tag="L1V38_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315407.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35636..36061
                     /locus_tag="L1V38_000838"
     CDS             35636..36061
                     /locus_tag="L1V38_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315408.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36549..37250)
                     /locus_tag="L1V38_000839"
     CDS             complement(36549..37250)
                     /locus_tag="L1V38_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1315409.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37266..37706)
                     /locus_tag="L1V38_000840"
     CDS             complement(37266..37706)
                     /locus_tag="L1V38_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1315410.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37706..38281)
                     /locus_tag="L1V38_000841"
     CDS             complement(37706..38281)
                     /locus_tag="L1V38_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBN1315411.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(39129..39608)
                     /locus_tag="L1V38_000842"
                     /pseudo
     CDS             complement(39129..39608)
                     /locus_tag="L1V38_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(39767..40468)
                     /locus_tag="L1V38_000843"
     CDS             complement(39767..40468)
                     /locus_tag="L1V38_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1315412.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(40576..41985)
                     /locus_tag="L1V38_000844"
     CDS             complement(40576..41985)
                     /locus_tag="L1V38_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBN1315413.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(42033..43898)
                     /locus_tag="L1V38_000845"
     CDS             complement(42033..43898)
                     /locus_tag="L1V38_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1315414.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(44019..44869)
                     /locus_tag="L1V38_000846"
                     /pseudo
     CDS             complement(44019..44869)
                     /locus_tag="L1V38_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(45179..45892)
                     /locus_tag="L1V38_000847"
     CDS             complement(45179..45892)
                     /locus_tag="L1V38_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBN1315415.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(45960..46286)
                     /locus_tag="L1V38_000848"
     CDS             complement(45960..46286)
                     /locus_tag="L1V38_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1315416.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(46409..46636)
                     /locus_tag="L1V38_000849"
     CDS             complement(46409..46636)
                     /locus_tag="L1V38_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1315417.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(46958..48211)
                     /locus_tag="L1V38_000850"
     CDS             complement(46958..48211)
                     /locus_tag="L1V38_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1315418.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            48272..49012
                     /locus_tag="L1V38_000851"
     CDS             48272..49012
                     /locus_tag="L1V38_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315419.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(49098..49856)
                     /locus_tag="L1V38_000852"
     CDS             complement(49098..49856)
                     /locus_tag="L1V38_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1315420.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(49853..50881)
                     /locus_tag="L1V38_000853"
                     /pseudo
     CDS             complement(49853..50881)
                     /locus_tag="L1V38_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(50901..54068)
                     /locus_tag="L1V38_000854"
     CDS             complement(50901..54068)
                     /locus_tag="L1V38_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315421.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(54292..55176)
                     /locus_tag="L1V38_000855"
     CDS             complement(54292..55176)
                     /locus_tag="L1V38_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1315422.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(55271..55708)
                     /locus_tag="L1V38_000856"
     CDS             complement(55271..55708)
                     /locus_tag="L1V38_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315423.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        16072 a        11746 c         9617 g        18437 t
ORIGIN      
        1 tttttaattt attgcccgat aatatataga aataaggtct agttactgtt ttttttaaat
       61 gattaataaa taacaacttc tttctatgaa attgcaaagc attcatcttc ttttccgcta
      121 acgatatatc cgtcagtgct tggtacactt tactaaaaag tatgagattg ccgatatctg
      181 gataggtgtg ctatactaca gaaaaagata tacaatctgc caccgggtag gataaagagg
      241 atgatcattc cattaggtct ttgaagggat gattttcctc tttttgtgta tttttttata
      301 gttaaggagg aatgtaagta tggcatggat ggaattaatc atagcaggaa ttttggaagt
      361 attctggtca acgatgatga aatggagtga tggtttttct aaaatcaatt attcttttta
      421 cacagtgatt ggcatgattg ctagttttta ctttttgtca aaggcaatca aaagtttgcc
      481 gatgagtctc tcttatccta tctggacagg gattggcgca gttggttcgg tcataattgg
      541 tgtggtcttg tttcatgata agctgaatct ttccacttgg ttctttgtgg ggatgctact
      601 catcagtatc attggcatca agattactag cggccactag acacttggaa taagtactga
      661 tcagaaaaaa taagcctttt tatttaatat tcaatttttt tatgaaaaaa taagaaataa
      721 gtccaatgac ctagcgactt ctccactcat caggtgtatg cttgtactat ctatagaaaa
      781 ggagtgaata tttttgaaaa gtctttcggt ccaagaatta tccaagaact ttggtcacaa
      841 acaagccctc agcgatgtca gttttagctt atcccctggc aaaatcgttg gattagtagg
      901 tcctaatggc gctggaaaaa caacgatcat gaaagctatt ttaggactga tccattactc
      961 agatggaaca atctgtattg gtgaaaatga gatttctccc tctagtcata aagggttgga
     1021 acaagtagga gcattgatcg aatacccggg tatctatcca ttcttaacag gctatgatca
     1081 tctgaagtta ttctctgaaa ccaacgatgt atctgctatc gacactatcg tgaatcagct
     1141 caagatggaa aagtacattc acaaaaaagc gaaatcctac tcgttgggaa tgaaacaaaa
     1201 attgggaatt gctcttgcct tactgaacca tccgtctatc gttattttag atgagccgat
     1261 gaacggtttg gatccacaag caacaagaga tgtgcgaaaa atcattaccg acttggctac
     1321 tcagggcacc tctttcttga tctccagtca cttactcagc gagcttgaaa aaatggtcga
     1381 tgagctgatc ctgatcaatc aaggaaagat catcaaacaa tgtacaatgg ctgaattgaa
     1441 ccaaacagcg caagatttca tcgttatctc tacaacaaat gatctagctg ctcgaacgat
     1501 cttgacagaa gctggatata ctttggaaga tcctgataaa atcaagcttt taaaagaaaa
     1561 cgaagaatta ttaggaaccg tgatccagct attgtctgca caaaatatcc atgtgacaga
     1621 cgtccagcat ctgacgaatg atttggaatc ttctctattg gaaattctgg attcagtaaa
     1681 gggggaagaa gaaaaatgac attgcttgta aaacaagaat tatttaaatt gatcaagaaa
     1741 aagtcaactg ctgttttatc tgttctatta gttgttttgc tcataggaac agcacttcta
     1801 gccaaaaaat acacgacgat cattgatcca gttgaaatga ctgctcagct ttttagtgcc
     1861 acatcttgga ttgtctttat catgattgca gctgcaagca cgatcatttc gatggaagca
     1921 caatatggta cattgaaaaa tctcctttat cgaaagtatt ctcgaggaga aatattagta
     1981 agcaaatgga tcacattagt tatttattct gtttatttat accttttagc tattattgtc
     2041 actgtgttga tgaaactgat tcttttccct tcgatttcct tcacggagaa ggtttctact
     2101 ggtcaaacac tgatccaaag cttgttcact tatactttgg gtagttatat cggtttatgg
     2161 ctgattttaa gtttagtgtt gatgattgct tgctttatca atagttccgg cgcatccatc
     2221 tcagcaggaa tcgtctttta ttttgcttcg tcaatcatat ctggtatcct tattgcactc
     2281 atccaaaaat gggagtggat caaatggaat ccgatcagta tgttgaatct gcaaaaccaa
     2341 attggaaacg aagagatcat gaagcaattg actcatcttt ctactaatca aatgctattc
     2401 ggtaatttag cttacatcgt tttgttctta gcattaggat atctcgtatt taagcgaaaa
     2461 aatgtatgat gactcatcaa aaaagaggct gtgaaagaga cgttcagcct tattgccgat
     2521 tggctgtctc ttaaacaccg tttattctga aaaaggagct gtgacaacat ttgtgtcaca
     2581 gctcctttcc tagtatgttt ttgaataaac gacaggctca caacctctct ttatacttct
     2641 tttatacttc tatacgtgaa gcatcccagt ggcaaataaa accattgcaa tcactccgac
     2701 catcgtcaca cctataagta aaatcttatc taagtggata tgttgtacag gctcgttttg
     2761 ctccttacgt gctttgaggt aaaaataaat gcctggcaag aaaagaacaa gaacaagcat
     2821 tacttcatta aaggctacga ctagcatagc ccatacttga aaggcacttg ctaaaagccc
     2881 tactaaaaat tggacccatt ctttccgctg ataagaaagt ttcatttggt acaatcctaa
     2941 gaaaagccac gtgaagaaaa tagctgctgt accaagtgtg taagcaaagt tataagcact
     3001 gtcagtgaat aataatgaaa gtaaaaagac attcgtacat aacgtcgtca atacgatagc
     3061 ataagttggt gccccatttt tgttgagttt tccccatgct ttaggcaaaa gtccgtcttc
     3121 agccatgttt cccattgttt caatcggtaa gatcgtccat gagagccaaa caccaactaa
     3181 agaaatgatc aaaccgccgt tgatcacgac tgctccccat ttaccaacca tcatttcaaa
     3241 cacatagccc atagcaggct gcgccttgat cgtttgcagc tgattcatcg tcattgtccc
     3301 atatggaagc atggaaacca agacgtaaat aataatcaag ccgaatatcc ctagaatcgt
     3361 tgctttccca acatctgatt gtttttttgc tcgtgaacct acgacagagg ctccttcaat
     3421 accaacaaat acccaaagca tcaccatgat gcaactcaat acttgactgg aaaacgggat
     3481 cggctgtcca ttcgcattca atataatgtc gctagaaaag ttatcaatga attgttggat
     3541 cgaaaacgtg ctgatagcta ctacaataaa taaaaataat ggcactaatt tacagaatgt
     3601 gacgatagca ttgacgaaac tagcattttc gactccccga ttcactagcc atgcatatcc
     3661 ccataaaaag actgtactca tcacgatcga tgccagattt tgcccacctt caaatactgg
     3721 gaagaaatat cctaatgcgc tcatcaacaa tgttgcaaaa gctacgttgc ctaaccagca
     3781 tgtgagccag taaccccaac cgctgataaa accagcgaaa cggccaaaac cttcttctgc
     3841 gtaactaaag atcccgcctt ttaaatctgg acgtttttta ttgatattat tgatcgacaa
     3901 ggagagcatc aacattgctg ttcctacgag tacccaactg aaaatagctg ggccgccagc
     3961 cgatccggag atgtccgtca taataccaaa tacgccacct ccaatcgctg aaccaattac
     4021 taaggcagca agtggaatta aaccaattcc ttttttctgt tgctctgtat ccatgtaagc
     4081 atcctccaaa ataaaaccgc ttttatcaaa aagtataaca aacctttttt atttttactt
     4141 aattaataaa aactttaata gaaatataat tctaccggct tttttctcat tatacaagca
     4201 aagcgcctag tccctttcca aattacacca ccaaaaaact taaaaaagat gctatactaa
     4261 aaggaaagaa ttggaggatg atccatgaac attttatata tatcgatttc aggaaatacg
     4321 cgtgcctttg ccaaacatct agcagaatat gctgaaaaaa tgcatgcaga agatcctgtc
     4381 aatcctgaag ttactttaaa agaaatccat gaaaatagtg attttacgaa agaaacagaa
     4441 ccatttttta ctttcgttcc tacttattta gacggcggaa atggtttaga taacggtgat
     4501 acagaaatct tgaccgaaac gatgcgtgaa tatctggaac atgaagacaa tcataaactt
     4561 tgtcttggtg tagtcggtag cggaaataaa aacttcaata atcagtattg tctaacagcc
     4621 aaacaatatg cacaaacatt tggctttcct ttcttggcag attatgaatt acggggaaca
     4681 ccatctgatg tgacacgaat ttatcagatt ttagcagaaa acaataaata ataaaaaaga
     4741 agaagctgaa aaatagattt cagtttcttc tttcgtttct attgtttcta tcatattaag
     4801 ctttgacatc catcacaggt gcttttgctt ttgctttacc tgttttttcc aagacaaagt
     4861 tttttacacg atccatattg gttaccaaga cgatcatgga tgtttctttg cctgctgctt
     4921 tgatcgcttc taagtcagct tctgctacaa gcgtatcagg tgtcacttgc tgcccttctg
     4981 ttactttcac atcaaatggc gtaccgccta agtcaactgt gttgattccc atatgaagca
     5041 agatttctaa accatttggc gttgtgatcc caatagcgtg tttcgttggg aagacagagc
     5101 tgactacccc agtaactgga gaatagatat gtccgttttc tggttctaca aagtagcctt
     5161 cacccatcat cttttgtgca aaaactggat cacttgcttt atctaaagaa acaactgttc
     5221 cgtcagcaac tgatgagagg atagtcacac tttcagctga agtttgaggt actacttttt
     5281 caggcacttc atttactgtg gctgtttcag tcgctaattc ttctttttct aaacggtctt
     5341 taggaatacc gaagaagaat gtagcaacga agccaccagc ataagctgcc aataatccaa
     5401 ggatgtagcc taaccattta ccgtcagaga tcaatgggat caaagcggct cctgaaggtc
     5461 caatagcgat agccccgaca tttccgatca ttccgatcac tgccccgccg atacctccac
     5521 cgatacaagc agtaataaat gggcgtccta gaggtaatgt tactccgtaa atcaatggtt
     5581 cgccgattcc taggatcccg actggtaaag ctcctttgat catttctgtt aattctttat
     5641 cttttttgca gcgaatccat aatgccaatg ctgcacccac ttgtcctgca ccagccatcg
     5701 caagaattgg aagcaatagc gtacgaccag tttcatcaat catttgcaca tggattggag
     5761 tcaaaatttg atgcagtccg aacataacca tcggcaagaa taatgtgcct agaacgaagc
     5821 cggcaaatgc tccaccaacg ccaagtaccc agttgatccc accgaccatg ccatcagaaa
     5881 tgaaacctgc taaaggcatg atgaagaaaa tttcaatcag accgatggca atcaatgaaa
     5941 gagttggtgt aacgatgata tctaccgcat caggtactac tttatgcagt tttttctcaa
     6001 cgattgacaa tagccaaaca gcgaagatga cacctaggat cccaccttgt ccagctgcaa
     6061 gagcttcacc agtaaataag tttttcagtg gtgcttccgg attcatccct gtcagcatca
     6121 caacggcccc gataactcca ccaagagttg gtgttgcacc aaaaacttgt gcagcattga
     6181 tacctgtata gataactagg tagctaaaca tcccgttttt caagatgttc atcacatcga
     6241 tatattgttg ccatgttgct gcatcaagtg ttccggctgt gactaagttt gctaaaactg
     6301 cggcaatccc tgccacgatc ccagtaccga caaatgcagg aatcattggc acaaagatat
     6361 tagaaatgtc ttttaatacc gatttgattt tagatggttt ttgtttcgat ttttgtgccg
     6421 ctttcatttc ttgtgcccgt tcgtttacac ggtcttttcc agatgctgat gaatttgctg
     6481 tagctgtact tacagaagaa agtttttctc ctaatttcac gcctgccaaa tcaaccattt
     6541 gctgtgctac tttgttcact ttcccaggtc cgatgatgac ttgaagctgt tcatcttcta
     6601 ctacaccaag cactcctgga atcgctttta attcagagac atttacaaga tcatcattga
     6661 tgatcttcat acgcacacga gtcatgcagt ggacaatgct ttctacattg cccatgccgc
     6721 ctgccccttt ataaatttgt tttgccagtt cttccaaagt cagttcgttt tttgccatgg
     6781 tcttttcccc ctcataaggt cccttttaca aatccgtttg cttcagctaa ttttgcttga
     6841 gcttcctctt tatcactatt tgtcaaaatc atgacgatag ccagcttaac attttgatct
     6901 gcttcttcaa agtacttttc agctgtttcg taatcagctt ctgtcgcttg catgatgatt
     6961 cgttttgagc gttcgattag tttttcattt gttggtttga catcgaccat caagttattg
     7021 aatactttac ctataccaat catactgata gtagaaatca tattcaagat aagtttttgt
     7081 gctgttcctg acttcaatcg agtagagcct gtcaaaaatt ctggacctgc atcgacttcg
     7141 attgggaaat ccgcgtgttt actgatttcg gcttgtttat tgcaagaaat cgttcctgtg
     7201 acagcaccga tcgattttgc gtaatctaat ccaccgatca catatggtgt acgaccgcta
     7261 gctgcgatac caataactat atcatttttt gtcaaattca gcttgattag atcttcttgc
     7321 cctagctcat aagaatcttc ggccccttcg acagctacag tcattgcttc ttctccacca
     7381 gcaattagac ctatgaccat ttccggttct acaccgaatg tcggtacgca ttcagcagca
     7441 tctaacacac ctagtcttcc acttgttccg gctcccatat aaatcagacg tccacctttt
     7501 ttaaaggact caatcgtgtt agcaatcact ggttcgatac ttgtcagttc tttttcaacc
     7561 gcagcggcca ctttctgatc ttctttgttc attagttgaa cggcttgaga aatactcatc
     7621 tcatctaatc caaaagtttc ttggtttctg cgttccgttg ttaggttctc taaattgatt
     7681 ttgctcattt ttatcttcct tcttttctta taaattgata gttcatacca gctttgattt
     7741 ggttgatcaa tggtagctct tctttgataa ctttagctac tacattcact ttttcatccg
     7801 ctggcaaatc atatttggtt aattggatct cacccatata gcgcaaatac ttttcgttat
     7861 ctaaagtaat agaccctttc atacgcgtag ctgtatttct tgctgggata ggcggaatct
     7921 ctcgaaaacg tgcatctacg cttcgtatga catctcttgc atcgtcttgc cgattcgtat
     7981 gcttccctaa tatatattcg taaaattctt catctacagg ttccgtatgg agcaagactg
     8041 tctgttcttt ttggaaagaa gcaaattgct cctgaacgtt ttctgacaga cctgcatctc
     8101 cgatgtaaac aatatccgtg ttacttgcta atagatctag agcgcctgca agaggatgga
     8161 tccctcgatg ttcttccaaa gttggcaatc cttgatatag tgggcctctc aactctgtat
     8221 ctcctggtac aaaaccttgg acaaggagac cttgaatttt gagccattga ttttttttct
     8281 gataccattc tttgtccagc cctgtttcgg gacgtggata ataattatgc caagcttcaa
     8341 tctgtgagaa atcagcttct gcttctttca attcatcgat atctttaggc gtgatcgtgc
     8401 tagcattcaa actgattttc aattgatgtg accagtcggc aatctgctga ttggaaatat
     8461 gataatccat tcttaaacct gttacaccaa ttgctttcaa aggcgttaga tcttctaatg
     8521 aaaaacccgc tcgttccaat gcctctcctg aaatatcgac catcaattct agtttattct
     8581 ttttcgcttc gcttcctagt tcgatcaatc gcttttgata tgccgaaaca tcatcttctg
     8641 gtatatgcat ggaagtgaaa ataccgacaa agccattgga tgccatttgg cggatatact
     8701 gtttcttctc ttctgacaaa gaatcgttca taaatattga aaagccaaac atattatccc
     8761 tctttttctg tatccgtctt catttctatg actagagtat atatctaaag aaacaaaatt
     8821 tcaatacttt tattaaaata attaaatttc atttctaaag gttgagttta tattatcaaa
     8881 agaattgtca taacctaaaa aaggcactgc taagcaaaag cagtgccttg aaatatttta
     8941 tttaaataac acaaaaacat aattactcat aagaaaccaa ttctgtatta tctaccatga
     9001 atgtaaagaa cccctcatta ggcatcggat gaaaataagc attgatcact cttatcaagg
     9061 cattatggca aactaacaga tagacatttt cttcgtcttc gatgcattct ttcaataaag
     9121 gaacgatccg tgcatacaca tctaagactg actccccatt tgggaatcgt acagcgaacg
     9181 ctaaacgtgc tttttgaaag ttctcatctt tgcttggcag tccatcataa tccccaaaat
     9241 ccatttctac caatcgttca tcaacggtca gcggcaagct gagacgatca gcaactgctt
     9301 gtgctgtatc tcttgctcgt tgaagagggg aatggatgat tttcgtgatt ggaacaggca
     9361 aatctactac cttttctgct agtttctgtg cctgcatctg tcctttttca gtcagcggca
     9421 catctgcccg tccgcaaact aatccttgtg cgttccaagt tgtttctccg tgtctcgtta
     9481 cataaagcat gtgattctct ccttcgttgg caaagttccc cttaaccata ccttgttgtt
     9541 cttgagatta caagggttag attctctcaa gagaaataat ctcagtagat actttatcca
     9601 ggaaggtttg atcatgttcc actagtaaca tggcaggttt cacgttcaag atcagttgtt
     9661 ctaattgttc ttgattgaag acatccaaat aattcaatgg ttcatcccat gtatatagtt
     9721 cagctggctg tgataaagat ttagccaatt ccactttttt ccgttggccc atactcatct
     9781 gctcgatctt gttatgaaaa acatctcttt ccatcccaag ctttcggagg ttgttcaaaa
     9841 atgcttggta gtctacttgg tttttctctg caaattccgc caacgttcct cgattgtctt
     9901 cataattttg gcttgcataa ctaatgctca gatgttttgg ctggtatttt tctcctataa
     9961 ccttgccgtt gaatgccccc agaagataat ggataatgga tgactttcct gcaccgttag
    10021 gacctgaaat cgccacccgc tgatgaggct cgattgtaaa atgaattggc tcgaataaca
    10081 gattttcata ccctaattga agatcttcta cgcttaaaag tcgcttatgg tgagacgctt
    10141 ggctattcat cgtcaaagaa tcgatatatt cgatatcttt taatagtttt tctttctcgc
    10201 tgatctgggt ctccatccga ttcacgattg ctttggatcg tttcatcgtc cgtgcagcat
    10261 cagcacccac tgctccttta ttcactcgtc tagattcagt atcgatgaat ccgacttgtt
    10321 tctttgtttt atctccttct cgggaacgag accattcggc tttttcagct gctgttttct
    10381 ttagcctact gacttctttt ttcaattttt cattttgagc catttcaaat tcatcacgaa
    10441 gttttttctg ttcttcatag atagagaaat tcccttgata aagttccagt tgactttttt
    10501 cgattgctaa aacatggtcc actacttcat cgataaatcc ccggtcatgg ctgaccacga
    10561 tgaagccttg ttttttcttt ttcaaataag ccgctacttg ttttctacca gagatatcca
    10621 aatgattcgt tggttcatcg attaacggga aatgagtgtc atccacaaat aaaagtgcca
    10681 gtaggacttt tgtcttctct ccccccgata gtgtgctgaa ttctctccat aagatttcag
    10741 gatctgtttg catcaattgg agctctcttt cgatttccca tatctcaaaa tccgtaatat
    10801 catttaacac gtaataggtt aaacgttctt tatcttttgt ctgttgcggg aaataggcaa
    10861 attcttgctg atggattact tgcccttgat aaggtagttt gttttgtaga atattcagta
    10921 aagttgtctt tcctcgaccg tttcgtccga taagtcctag tttccattgt gtgtcaaaat
    10981 ttagatttgc ttgttcaaat aataatgtgc cttggctgtc gtagccgaat gtcagatttt
    11041 ttatttcgat tttagacatt ttccatcacc tcgtaaaaaa agaccagtcc tattttcaga
    11101 actggctaaa gaggatgcaa gggttggata cacacaaaaa gacccataca tcgaaaaaac
    11161 caagccaatc ccgaaaatct gcacactgct tccttgtctc cacaaggtac agtctgaatg
    11221 cagctttcat caatcgactt aatttttcaa tgcacggatc cctcactttg tcctatattt
    11281 gaaattacga tagcataaag aaaatgattt tgtcaactac ttcgggagga tggtgaaaaa
    11341 tctgctaagt gtctgtccta agatttttgt tttttctaat gtttgcctgt gttccattgc
    11401 ttcttctaaa cctattggac ccaaatgaat acttaagaca attgggagaa aatcagaaag
    11461 tccttctagc tcttggtctc tacttccgca aatagcgatt attggttttc gatatttttt
    11521 tgcaagcact gctacaccgt atggaacttt tccgtggatc gtttgctgat cgatccgccc
    11581 ttctcctgta atgatgacat ctgcttgttc gatctttttt tccaatccag tgatttggct
    11641 gactaaatcg aaaccagaaa ccatcttcgc tcccaacaaa aaaagggctc caccaatacc
    11701 gcctgctgct ccacttcctg gaatatcatc taaatccacc tcccagaaat cttttatttg
    11761 ctgagcaatc tttcctgctt gtttatctaa gaaagctagc gtcgtatcta ttcctccttt
    11821 ttgtcttcca aattgccaag cagctccttg ttgacctgta tatggattgg taacatctgc
    11881 agcgataatc aattttactt tagaaacaag aacgtttctt cgatcaaaat gaagtttttt
    11941 agtagataat aaaggatttc cttctgtgta cccttctaaa gaagcaccca aggattggag
    12001 taatcctaga ccaccatcgc tacacccgct tcctcctaaa gtgacaataa tttgttctac
    12061 ttcttgaagc agtgcatctt taataagttc tcctaaggca taactggaag caagtcggat
    12121 agtttgatcc gttggtttat caagtagatc taaccccaat gcttgtgcag attcgatgac
    12181 tgcggtgttt tttccttgcc aagttgtcaa taaatagctg atttttcgct gacggaataa
    12241 gagatccatc ccatcaatgg tacgccatgt tcccctgagc gcgtaataga ttgcttctgc
    12301 agtattttct ccgccatctg caatcggcac attgattttt cttcctttac gatcttccca
    12361 gccatttaga actgcctgat ttagttcaaa tgaagaagca cttcctttaa atgaatcaat
    12421 tgccgccaaa atatccatct gtatccctca ctttcttctt aagtaagaca ctttttttca
    12481 tttttttcaa acaaaacaat gctattttct tccatttttc tatatactaa aagggaactc
    12541 attgaataaa ggagagaaaa aacatgaaaa tcgcaatagc tggggccgga gcaatgggca
    12601 gccgaatcgg attgatgcta catcaaagcg gaaatgaggt cctcttgatc gatcgttggc
    12661 ctgctcacat tgaagccatt cgtacaaatg ggttgattgc tgactttaac ggtaaagaag
    12721 tggtcgcaaa actgccaatc tattcaccag aagaaatcat cgaaagcaac gaacacgtgg
    12781 acttgatcgt agcattaaca aaagccaatc aattagatga tatgttttgt tcgatccaat
    12841 ccattattac tgacaatact tatgttttgt gtttactaaa tggattaggt catgaagatg
    12901 tactggaaaa atatgtgcca aagaaaaata tcttatttgg gatcacgatg tggacagctg
    12961 gtctagctgg tcccggaaaa gtcacattgt taggtgatgg agaaatcgaa ctagagaact
    13021 tggaaccaga aggcgaagca tttacaaaaa aagttgtaga agtctttcaa gaagcaaatt
    13081 taaatccgat ctatagccat aacgttcgtt attccatttg gcgaaaagct tgtgtaaatg
    13141 gaacattgaa tggtttatgc acgattttgg attgtaatat tgctgaacta ggcgcgcaaa
    13201 aagcggcaga gagcatggtt cgaacaatcg tatctgaatt tgcttctatc gcagcaaaag
    13261 aaggaatcat actagatcaa gaagaagtgt accaacatat tgcttctact tatgatcctg
    13321 acaacatcgg gttgcattac ccatctatgt accaagacct gatcaaaaac catcgtttga
    13381 ctgaaatcga ctacatcaat ggtgccattt ggcgaaaagg acaaaaatat gatattgcta
    13441 caccatattg tgcctttttg acccaattag tccatgcaaa agaaggaatc cttggcgcag
    13501 aataaaaggc tctctgatga gaatcagctg aatcagcagc tggttctctt tttttaagcc
    13561 caataaaaga tcaaaaagaa aacacaactc tcatgatgcc ataagaattg tgcttgtttg
    13621 tttcagtaca taatctcttc aaaatgtagg ttttttattt gttttcaaca gaggagaggt
    13681 catattcgta ttgctcataa atagtggaat cgttagtgat aaatcgtttt gcccaatttt
    13741 ctgcatcata aaattccaat agctctgata ggattggctt aaatggtgta tgcagaaatt
    13801 ccggtaattc atctaaatca cgttctcgaa gcaaaaaaat attttcagga cgataaaaat
    13861 gataatgagc aatcgcttga ttatccgtca ctagtttctt ttgaaaatac atggattcaa
    13921 atgtccgcaa agtcactcct tgctgaccct cccgcaacag ttccagaatc ccgcgcgatt
    13981 cccctgtttt tttcaggtac tcttcataag taagatatcc aggttgttca ttccctcgat
    14041 gtggaagaat gaaatagttg gtcgtaacat ctctttttat aaattcctgc ttatagcttt
    14101 ctgctcgttc ttttctccca ttattcgttg caccaaaaaa tagatccgtc tttggttcgc
    14161 tagaagaaaa attcatatgt ttcgaataaa atgaactatt atgtttcagc ccaagttctt
    14221 ttgcttccaa aaaatcaaaa tgataaatct catcgattgc cggttcatct tgtgcctgct
    14281 tcagcatcgc ctcgtgttct gctttgaagt gattccaaaa aaataacaca atttttgcat
    14341 tggtaaatgg gcgcacgcgt cgagccatct ccatatcaaa tccataatct aaaaaaacga
    14401 tcagctgata atttgccaac tgttgtctag ctgatttaat gaattccgac tgtagtaaat
    14461 cttttccgga ccaaacatct aaagagcgga tggaaggcaa aaaataaagt gatttatttt
    14521 ttgcaactag cagtacgtca tttttgttca tcttttccgc ctcactttct ctgtcacttt
    14581 ttcctatgat agcctgttta aatagtaaaa agccagtaaa acgtttccta tatttgtatg
    14641 aaaatttaac atttgtatga aaatatgatg aaataaatca ttcttctatt aaaattcgcc
    14701 taaaagtttt ctgaatagtt gtaattgtct gaaaatttgt tatcattagt cattgttaaa
    14761 tattgctatt tattcttaat ataaattttg attgtgaatt taaaagaaag aggtcattta
    14821 tggaagataa aaaattgaaa aaacaactta gctccagaca tatcaccatg ttagctttag
    14881 gtggagcaat cggtgcaggt ctatttaaag gaagtggcga agcgattggg atcgccggcc
    14941 cttctgtatt gattgctttt ttgattggtg ggctgatttt atatatcgtg atgaaaggtc
    15001 tgggaaaaat cgttttaagc ggtggcgaca cgcatcacgg attatctggt ttgatacgcc
    15061 cttatctagg tgctcattct gctgatttta ctgattgggt ctactggtct atgtggatta
    15121 tcaatatcat cgctgaagct gttgcagctg cttccttttt gcagttgtgg ttcccgcaca
    15181 ttccagcctg ggtatttgtt tttatgttgg ctgttttaac tacgatcatc aatctttatt
    15241 cggtacggtt attcgcagaa acagaatatt ggctggcttt tgctaaaatc agtgtcatta
    15301 tcttactgat catttttgct acttatcttg tcggtcagca aatgttgggc acaggcgttt
    15361 tccctaccct tcagcaattg actgaccatg gtgggtttac tcctcatggt atgaagggaa
    15421 tcatcagttc tttgcttgta gttatctatt cttacggcgg ttctgaactg attgctatca
    15481 cggtaagcga agcagatgat cctaaacgtg cgattcctaa agcaatcaaa ggtgtcatgg
    15541 gaagaatcat ttccttttac atcattcctt tgtttttgct tttgattctt tttccttgga
    15601 atactttagc aggcacgaat gtcagtcctt ttgtgatggt atttgaaaaa atgaatatcc
    15661 catttgcagc ggatatcgtc aattttgtga ttgtccttgc tttgttctca tctatcaatt
    15721 cgggtgtgta tgcatcttca agaattttgt tcttccgttt gaaggatcga aaaggttcct
    15781 ctagaaaact agctgtttta aacaagcatc aagtaccgca acgtgctgtt ttattttgta
    15841 ccagtgttct ttatcttggt gtagctcttt cttattttgt cggtgacaaa ttatttggct
    15901 atctggcagg ttccctttcg tatacagtat tattgatctg gatcattatc agtgcggcat
    15961 cctttgtact ggcactaaga aaaggaacat tatgggataa aggaatcagc ttttttgcat
    16021 tagctgtctt aggattgatt ttccttggta tcctgttcac gaactccatt ggggtaactg
    16081 tattgactgg cctgctttac ctgttcattt atttcagtta tcaaaaaaag aatgatgcgt
    16141 tcgtattgac gaatgaatga aatcgataga aaattttatt ttatttatgt ggaatagatg
    16201 gagctattga agaaaggagt tgtgacaaaa gtcttgttgc aactcctttt tccgaataaa
    16261 cagtctcatg acctcttggt aaacggtgtt caaaaaccct ctgtgcaaaa taattgattg
    16321 ttctccatgc tcatgacatg atagaagaaa ggaatgaaaa aaaggagttt gttttaaatg
    16381 aaaaagtatt ggaagttttt gttgatgatc ggtgtttcaa cggtagttat gtttggtatg
    16441 atgtacttga atgtctatgc gctcgatcat atcttcttca gtcgtacacg agtattcatg
    16501 gcgttgatga tgggtgcagt catggcagtc atcatgctgt tgttcatgtg gaaaatgtat
    16561 gaaaacaaaa agataaatgt tatgatctta gccgctagtc ttcttgtttt tgccggttcc
    16621 ttgtttatgg tacgaagcca aactactgtc aacgacacag cttggatgaa ggccatgatt
    16681 cctcatcatt ctatcgctat cctggcaagt aaacgagctg atttaaaaga tcctgaagta
    16741 aaaaaattag cggaagaaat cattcaggca caagaagaag agatcgacaa aatgaaaaaa
    16801 atgatcaaag aaatggaatg accattatcc gtccaaataa aaaaagagga tgttccagaa
    16861 gttatcagct tcaagaaata agaagaagct acttctggaa cgccgtgaat aaggggttgt
    16921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcctattt
    16981 ttcgtttggt taggcttatt accgcagatg caagcttttg aacaccgttt attaagaggt
    17041 tgtaaaatca gcgttctgac ctgagtatta gagagacaaa tggaaaaata gttcctcata
    17101 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcgagagg
    17161 ttgtgaaaaa gtcgcttagt ttcgcgtatt aagaaaaatt ttgtgaaatg gctttccaca
    17221 tttttgtata aatttggctt aataccgaga aactggcttt tgaataccgt ttattcgtaa
    17281 aagggattgt gacaaaagtc ttgtcacaat ccctttttat gtttttattg ttctaattgc
    17341 gctgtcttgc ttactgcttc ttgcggtttc acaaattttt ttgagattcc ccaacctgtg
    17401 aaggcactga ccatcgaaaa cacaggagaa agcaaactga aaaatacgaa tggcaagtaa
    17461 gtgagtgtag gaataccaaa tgtacttgct acgaaacttc cggcaattcc ccaaggcact
    17521 aagtagttga ttactgttcc accatcttct agcgttctac ctaatacagt tggatcaaat
    17581 cctgcttttt cataagtttc tttaaatgca ttaccaggca gaataacaga taggaattgt
    17641 tcaccaataa aaatatttac tccgatactt gtcatcaatg ttgtaaaaat caaatttggt
    17701 gtgttcgtca tctttcttga tactcgttcc atcacggttg agatcaagcc aaattcgatc
    17761 aacaatccac ctaatgacaa agttagaata atcaatgaca cagtaggcat catactttcg
    17821 attcctccgc ggctaagcag tgaatcgatt tgttggtttc cagtatttga aacaaaccct
    17881 gattcgatga ccccagccaa cttcgttaag gaagtttgtg ggttttgaat aaaaatcatt
    17941 cctactgcta cagcgatatt caacaaaatc gttaaaattg ccggcacctt tttccatgca
    18001 cacagtaaca ttaaaaataa aggaatcagt gaccagattg aaatagtaaa gtttgcttct
    18061 agaacatcag tcacttcacg aatagatgaa agacttgcgg ctttacttgt gtgtcctaaa
    18121 atcatgaata aaaagaaaga aacaacaaat gccgggacag ttgaccacat catatgcttg
    18181 atgtgtttga acaaatcggc atcaacaata gctgctgcta gatttgttga ttcggataat
    18241 ggagacatct tatctccaaa aacggcacct gaaacaatag ctccaacaac cagcgctgga
    18301 tttaagccta gtgttgtccc aataccgaaa aatgcaatcc caatcgttga cataacagta
    18361 aaggcactcc ctacagcgct acctacgatt gcacacacaa caaatacaga agggacaaac
    18421 cactggacac tgatcaattt gaacccaatg accattagag ttggaatgat ccctgcttgt
    18481 atccatacag caatcaatga accgactaaa ataaaaataa agattgggat gattcctggt
    18541 ttgatgccat tgatgattcc ttcgtgcagc caatctgtcg ggtatctttt tatcactgca
    18601 tacaacatga ccattccgat cgctgctaag atcgtgatat taggtgagac ctttaatccg
    18661 acaacgccaa tcgcaatgcc taaaacaata accattaata caagtgttgc ttctaaaaaa
    18721 cttggtgttc ctttttttcc catgataatc tctccttttt tagttgttct tatgttctaa
    18781 aaaagttaag atatcggatt actccgccgc aattcatccg cgattcctcc tttataaaaa
    18841 taaaaagacc tgttttaaac taaggacgaa tgactccgcg gtaccacctt aattaaaaac
    18901 agatctgttt ttcactttca aacttttatt caaatgtatg gactttccat gtaattcgtc
    18961 aattaggctt gatcggttca cagcgaccac cgactttctg aacaaaacac ctaaccgcta
    19021 ctgcgtgaaa agttgacttg tacgaagttt accttccata agatcatttg tcaatgaaaa
    19081 agaaaatatt ttttcatttt tctgaaaatt atttttataa ctttcacaca caagtttatt
    19141 ttttactaga aagtagcgcc ctcttgtttt tttcttgcta ctatttcttg atgttcttgc
    19201 ttgattcttt ctaatagctt tggctctttc aacagatcaa gagctgtatt ggcgagtagt
    19261 tctgctgcaa tcgcaataga agcaaggcct ttgtcacttt tagcagcagc tttgaattct
    19321 tctgtgtgtc cggcaatata tgtctcagag attgctaccg taggctggat tgttggtatg
    19381 acttggctga catttcctac atcagaagaa ccgagacttg ttctttgttc cgtttctatt
    19441 tcttcatctg gaacacctgc ttcttttgca tgctggaaga ataagtcatc aaaagaagga
    19501 gtaacgatga catcatcaac tgcattttgg aacaatccaa actcaaaagt cgtgcccgta
    19561 cttatcgcag cacctcgtac gatattttcc actttttcat atactttatc taatgtttgc
    19621 cgatttcctg cacgtaaata gaaacgtcca gcagcgtaat ctggaatgac gttggcagct
    19681 actcctccgt ctgtaatgat cccatggata ttgacatctt ttggcaattg caagcgtaga
    19741 gcgttgattc cattaaacac ttggatcaat gcttccaaag catttactcc tttttcaggt
    19801 gctgctgctg catgggaagc gacaccgtaa aatttgatgt cgactggatc attcgctaaa
    19861 gattctgtcg ttttcccata acgaaaagct ggatggacgc ataacgctac atcgacatcc
    19921 tcaaaaaaac cttctcgaac aaagctgcct ttagctgatc cgttctcgcc cccttcttcc
    19981 cctggggtgc catatacacg gatttctcca ccagtttcat caatgaattg cttcactatg
    20041 ctggcggcta atacggagta agtaccaaac aaattatgcc cgcatgcatg accaatacct
    20101 ggtaaagcat cgaattctgc caaaaaggca attgtgggac cgggtttatt ggaaatataa
    20161 cgtgcatcaa aggctgttcg gtgtccagct acttcttttt ctacccaaaa cctttctttt
    20221 tctaattgtt taatcaacgc tgctgaggaa taaaactcat agttacttac ttcaggatgt
    20281 tcgtggatat ctagagcaag tgcttgatat tctggtaaac gatattggat tagatccttc
    20341 aattggtttg ttgagattgt tgttgtcata aaaaattcct cctatgctag tcatttttct
    20401 tattttctcc cgaatgtttc ccatgcaggc acgcttgatc cttttgatgt tttctcgatt
    20461 actttgactg tgtcttctgt ttgataagcg tctactattt tttgatacgt tttattgttt
    20521 tcatcttctt ttcttgcaac gatgatattc acataaggac gtgcatggtc atccactggt
    20581 tctaagaaga tggcatcaga agcaggatta aatccagcat ctacagctac accgctattg
    20641 atcactgaaa tgtctacatc tgacaaagca cgtgctgttt gggaagcatc taattcagaa
    20701 atgtctagat tttttctatt ctcggtaata tcagaaacag tgggcgcttg tccttttgcc
    20761 ttatccactt tgatcaatcc agcagtttgc aataacagaa gagctctgcc gccatttgta
    20821 acatcattag ggattgctac ttttgctccg tctttgatat cagctacatc cttcaaagtg
    20881 ttagaataaa ttcccagcgg tgcattgaca gtatttccga tcgatactaa atcagttccg
    20941 tgttctttat tgtaattgtc taaaaagaat tgatgttgga aagaattcaa atcaatcgat
    21001 ccatctgcta aagccacatt tggttgattg taatctgtaa atttcacgta ttccaaatta
    21061 atgttctcct ttttcaaacg gtctttcacg ttgtcccata catctgtatc ttctccaata
    21121 atccctagtt ttacgatagt ttcttttttg tcagttgtat ctgcttttcc ttggctacac
    21181 cctgccaacc aaataattgc tacaaatgta atgactacaa aacgaataat ttttttcatt
    21241 ttttctcctc cactttcaat gtgtaatttt tttaatcagt tgattactga taaattgact
    21301 taaaaaaact aagattagaa tcaataatgt agccacaatc gttacatctg tttggaatcg
    21361 attataccct ctcgatatag caagattccc taatccgcct gcacctactg ctccagccat
    21421 ggtagtcagt ccgatcacgt tgatgatagt caacgccgag acccgaatga taccaggcaa
    21481 accttctaac aaatacacac gtaaaatgat accgattgga ctggttccca tcgcttctgc
    21541 cgcttcgatc accccaggat caacttctag cagtgcgttc tcgatttgac gagcaaaaaa
    21601 cggaacaact ccaaaaatca atggcactaa agctgctttc gcaccaatcg tcgttccaac
    21661 taagaaacga gtagtcaatg ctaaaagaga aagcaagata atgaaaggga tggaacgaat
    21721 gatattgatc agcttatcaa gtatttcaaa tagcagacgg ttagctagta atccattagg
    21781 gcgtgtcact actaacgtca cacctaagat gattccaatc atcccgccaa tgaatgctgt
    21841 ccaaaaagac atatatagtg tttgcttcgt cgcttcgaca aattcatccg gaatcaaata
    21901 aacattgggc aaatatgttt taaagaaatc agtcatttta tcttcctcct tcgatcactt
    21961 tgatacgact atctaaatcg tttttttgta aaatatttat ttttacacca gatttgatca
    22021 aataatccaa tgcttttttc cgctgtttgg tttctccagc taaagtaacg atcaaactcc
    22081 ctaacggcgt ttcttgtaat aactctacat tgccatataa aatattcgct gttacttgat
    22141 atttgctgta cagatgagcg attagaggtt cgttcgtctg atttccaata taacttaatt
    22201 ccaccagcca tttattggcg atctgatcgg caaaagcaga atgggcaatg atcgtttcta
    22261 atgcttggtc aagatgagta gctgttcgaa taaaatcttt ggtcaattct tcttcaggat
    22321 tgctgaagat ctggatgctg ctaccttttt caacgattct tccatcttcc ataaccgcta
    22381 ccttgttgca gatttctttg acaacttgca tctcatgagt gatcaggacg attgttaaac
    22441 ctaactggcg attcaatttt tttaacaatg caaggatctg aagggtcgtt ttcggatcaa
    22501 gtgcactggt tgcttcatca cataataata ccttaggttc attcgccaaa gctcgtgcga
    22561 ttgctactcg ttgtttttgt ccccccgaca gttgtttagg ataagcagat gctttttctt
    22621 ccaaaccgac aagttccagt agttcattca ctttttgacg acgttcctgt ttcgattttc
    22681 cagaatactt taaagaaaaa tcaacgttgt caaaaatagt tcggctttcc attagattga
    22741 aatgctgaaa gatcataccg atggcctttc tttcttttcg caattctttg ggagagagct
    22801 gactcagatt cgtctgattg acaatgactt ctcctgctgt tggtttctgc agcaaattca
    22861 tcacacgaac taacgtactt ttccctgcac ctgagtaacc gacgattcca taaacatcgc
    22921 ctttttcaat cgttaaatct acagaatcta ctgcctgtat ctctttttct ttttgtttga
    22981 aacatacaga aacatctcgc aattcaatca ttaaaattcc tccttatcta aaaaaagcgt
    23041 cctcaagaaa atgaaaatgt cattttcttg aggacgcttt tttgcgtgtt accacctcat
    23101 gttcaagctg tgttcacaca caactcctct tcaagtacga tcatactcta gcaagatatc
    23161 ggtcgcagcc gtcatcgcct tacatctatg ctcgggatga attgctcgat ggccattttc
    23221 caatagtcgt tccttgcttc ttctcagcta ccgaagctct ctgtcaaagg ttcttctatc
    23281 gtacttacca tttcaatgca aataatattc aaaaaaaaag tccttttact aacataaact
    23341 atgtcagtaa aaggacgacg tatcgcggta ccaccttttt tcggaagttt ccttccctca
    23401 agcccaacat ctcaaaaaga gagattggcg ttcgttttaa cggtcgaaca gttccgaatt
    23461 tgcctactta tcgacaaatt attctccaag gccattttca gcttttctta cttgactctt
    23521 ctcaccagcc agagcctctc tgcaaagttt ccaaacttac tttccttttc aacgaaatcg
    23581 atattttgtt gttgggatta atctacatga ggaaaactga aaagtcaagt acgaaattca
    23641 aattattttt tctatattta tttttctgtt tttttattta acatttcaat aacagttcga
    23701 agatcttttc cttccgcaag aagtttcaat ttttcctttt cttcgacggt ataatttcgg
    23761 acaaaactgg aatcaggtat caaaacaacg cctaatcctg ctcgtgaagc agctgttgct
    23821 cctactaaag aatcttccac tgcaaaggct gaactagctt ctaatcctgt tcgttccaaa
    23881 gctgtcagat aaggaatcgg tgaaggcttg ttctccgaca cttcgtctcc gaatgtaaac
    23941 gtgtccaagt aatcagctaa tttaaagtga tccaagatat ctgttgctct tttcgtaaca
    24001 gtggtcgtag caatgcctag tttcatatga cgttctttta agtctgccaa tatttctttt
    24061 gcatatggtt ttaagtggat ggctccgctt gtcagctgtt gataaaaata ttcttcacgc
    24121 ttcgctcgga cttcctgtac tttttcaggg ctacctgctg ctttcactaa aatatcaaaa
    24181 ctttgtttcc agttttttcc gccccaagcg tcaacgattt cttttgggat atggatatca
    24241 aattgctgaa atccccaaag ccagccatca cgatacgttt tttctgtgtc aactaacaaa
    24301 ccatctaaat caaatattgc acctttcatc tatacattaa tcctttccaa aacaatacac
    24361 atagtttagc acgactggtc caaaaagaac agaagcaaag aaccagcctt ctcgtttata
    24421 agagttcttg gaatcgacgg atatagattt tcttcacagc tgtcacaagc gccagataag
    24481 cgatgactgt agcaaataac cataaccagt aattgccagg aagtggcatc aagcctaatt
    24541 cagcaccaaa acttgtaaaa ggaaggacag aaccgacaat aattcctaat gtagtgataa
    24601 caaacatggc aaatgttgcg ttgctttgga taaatggtac tttcggtgta cgcagtgcat
    24661 ggagcactaa ggtttgtgtc catagtgatt cgacaaacca tcctgcatgg aataatgcga
    24721 tgaaaatcac tcgctgtgaa ctatccaatg tatggaaact tccgcccact acagcaggac
    24781 aaataacaaa atacatcaac aagtaagtag taatatcaaa tatcgaactt gttggaccaa
    24841 agtaaaccat gaattcccca atactagatg cattccattt ttttggctcg tccaaatatt
    24901 ctttatccat ccgatcccat ggcaaggaaa tgcaggaaac atcatagatc agattcaaaa
    24961 acaaaagttg taaaggcagc attggtaaaa atggcaggaa cgtacttgca atcagcacgg
    25021 aaaacatatt gccaaaatta gaacttgctg tagccttgat atatttcatg atattcccaa
    25081 aagtttctcg tccagaaaga aggcctcttt ccaaaatcgt caaatctttt tctaaaagga
    25141 tcacgtctgc agattctttc gcaatatcca cagctgtatc tacagaaata ccgatatcag
    25201 ccactttcat tgcaggagcg tcattgatac catctcctaa aaatccgaca gtatgaccat
    25261 ttttacgtaa agctgtcgtc aaacgtgctt tttgctgagg attcaatttt acgaatactt
    25321 catggtcttc agctacttgt gctaattcat gatcactcat ttccgagatt ttctcaccgg
    25381 taaccaattc attgatctct agacctactt gacggcacac tgaacgtgta actaattcgt
    25441 tgtccccagt cagaactttt acagctacac catgttcttt cagagctttc aacgcttgtt
    25501 tcgttgtttc ttttggtgga tcaaggaaag caagataacc aatcaaaacc atgtctgact
    25561 catctttgac tgaaaattct ccaacgacgc ttggattggt cttttgtgcg acaccaatca
    25621 ctcgtaagcc atcttcatta agtgactgta cttttgcaag tacggcttct tttcgttctt
    25681 ttgttaatgg tgtaacagta ccgccaagat caataaattt agaaatgttc agcatttctt
    25741 caatcgcgcc ttttgtgatc atttgtgttt taccagctgg atcagcaacc acaacactca
    25801 tacgacgacg ttcaaaatca aaaggaattt catccacttt ttgataattg atcttatctg
    25861 tatctaaagt ttctgttgct tcatcaatga tagccacatc taacaaattt ttcagccctg
    25921 tttgatagta gctatttaga tacgcatggc gcaaaacacg atcatcttca tttccttcac
    25981 aatccatatg atattcaaga atgattttat cttgtgtcaa tgtccccgtt ttatccgtac
    26041 ataacacatc gattgcacca aagttctgga tggcattcaa atttttgatc actgttcctt
    26101 ttttggccat cacacttgct cctttgacca aattcgtcgt aacgatcatt ggaagcattt
    26161 caggtgttag accaactgct acagatagtc caaaaagaaa agcttctagc caatcccctt
    26221 ttgtaagccc attgatgacg ataactgctg gagccatcaa tgacataaat ttgatcagta
    26281 gcatggatgt tttatggatg cctaattcaa agcttgattg aattggtttt tcagatagcg
    26341 tttctgctac atgaccaaat agtgtttcat ttccaacaga aacaatgatt ccttccgcac
    26401 ttccactgat gacattactt cccataaaga caagattttc gtaacttgtt tcgctttgct
    26461 gatcgtcttc acatactttc gcatgctttt ctactggata gctttcccct gtcaatgctg
    26521 cttgggaaat gaataaatcc tttgcggaca ataaacgcat atccgctggt atcatatccc
    26581 ctgctgaaag ccgaacaaga tctccacaga cgatttcttc cataggaatc tctgtgtact
    26641 ttccattacg ttttacagct gccgttactt tcacaagtga tttcagtttt tcagccgctt
    26701 gattggaacg tacggactga atcaacgtca ttgtcccgct gacgataacc atagtgaaga
    26761 taatggctac accgaaaaga tctttatctc caggagctgc taatacatat tccgtgatga
    26821 atgaaataat tcctaatgcg atcaacacta atgtaaatgg cgtgatgtat gctttcaata
    26881 tttctacaat gaatggtgtt tttttgccat atgaaatcgc attttcaccg taattttctc
    26941 ttgaacgttc gatttgttct tctgtcaatc catttgctga tgcatggaat agttcaaata
    27001 attcttgttt cgtttttcca gcaaaagctg catagatttt ttgtgtatct ttcttttttt
    27061 ccatctcaat ctctcctttg tgtccaaaag acagctgttc tcgctgcttt tggtctttag
    27121 ctattcatcg gatcgataga gaaaaaactg aaaggggctg agaacagata gataatagcc
    27181 ctggcctttc ctctagatcc ttgtttttcg aatgactgtc atccatttgt tctcatctcc
    27241 tttactaagt aattttaatt catgacttcc aatcattttt cgaatagtta tttttccaat
    27301 tagaccacct cctttttatt tttcaccgat ggggatttgc ggcaacaaaa aaacctctcg
    27361 ccaaatactc agcgaaaggt ttgaaaaagc atattaaaaa aagcttctca gatctcatcg
    27421 ttgagttttg acactgtaca acgtaaaaag cagatacctg cttttagcta ccttatgaaa
    27481 agccttatct cgacaattcc tgttctaccc attggcgtct ctcgacgttt ttgggcagta
    27541 gcctatgttt gtataggagc ctcacctaac aaatcttatt cggttttcct tcgttaatat
    27601 aacaactaaa aaagaggatg tcaaatcaat tttccatgtt tttcatactt tttttaaaat
    27661 acacacgtta tattcctgtc tcacgcggtt ttatttgtct cattttccac ctcccgctat
    27721 aatagaaata tagtaggaaa cgaggtgctg ttatggaaag aacacttgtt attatcaagc
    27781 cagacggcgt gagacgccat ttagtcggaa gcatcatcca acgttttgaa gcaaagggac
    27841 tggccattgc tgaaatgaag tttgaaacta tgactcctga attagcaaaa gaacattatc
    27901 agcacttgac tgagcgcagt ttttttgatg aactgatcga ttacatgact tccggtcctg
    27961 tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat cgtccgtaag atggttggag
    28021 caacaaaagc tgccgatgct gttccaggta cgatccgagg agactacgcg ctgccgggga
    28081 ctgaaaacat cattcacgct tctgattccc gtgatgctgc ggtaaaagag atcgcccgct
    28141 ttttcccgcc attcgatata aacaaaccgt ctgaaaaagc ggcgaagtga tacaaattct
    28201 aaactgctgg tctagttgct gggttcagca atggccagca gttttttctc taaggacctc
    28261 cgttgattct ttcctaacat atattcgagc actgtgaaga attcttggta gtctttcgtc
    28321 ttttcttccc ctaaagcagc agaaatcaat ctttgataat aatctgccat caatgtttca
    28381 tagatcactg tacttctttc tttatgtgat aagctccgtt tcatatcttc attcacacta
    28441 cgtgcctttt tcaaccgacc attttctata taaaacgaag tcaggttcat taaaaaagta
    28501 aagagatact gctcatgatt gttcaactgt gctaatcgtc gcattctttt tttgattttc
    28561 aaataattgt tctcaatgaa ccgatcactg aatatccaag gaaaatcagc tagaatagat
    28621 agttcaaatt gaccatagtc tggtatctgc atcaagtatt cttcaatgat tcggcattca
    28681 taacgtaaaa attcaaattc tgtctcagat acttctgttt tttcgaccat gtgaagattc
    28741 aaaaccaaat aatacagatc ttctgttttc ttaaaatgcc tacggttatt gctgatctct
    28801 ttataaggat caaagctgtc ttcttgtacc cgatctagca ttcgtctttt tttctttaac
    28861 tttattggtt catccagctg gtttcgcatc cattcatatt ctgcaagtgt catgttcatt
    28921 cgctctaaaa atgatctcaa tgttacaaat gacatttttt tcactgaatt tgtctcaatc
    28981 ccgactagag aagtcttaaa acagattcct tccgctaatt gggactgtgt caacttcttg
    29041 ttgactcgaa gtttcttgat caattcacca tcatacataa tagttctcct ttttaattta
    29101 aatttttcca cattcaataa atagatacgt taaaaaggaa aaatacacga aaaaaataaa
    29161 aaaatgtttt tttcataaaa aataccaacc ttcaagcatt agaatgttgt ctaactactg
    29221 aaggttggtt tgattgttta ttgattattt ttttgctgtt caacgtctgt tcttgttact
    29281 ggatataagt tggttgttgt tttattacca ttttttgaaa agacacttgt cgaatgttcg
    29341 cctttttgct tttcgattgc ttcattacgt tccgcttcat ttttatagtc atattttttc
    29401 ggatcaatcg tctcaaatcc gtttggcaca taaaaccgca agagattttc ctgattcagc
    29461 ttatctgaaa gacttaacgc agtcttgact ttttcctgat ctttggagat ttcctcatcg
    29521 attcctgctg ctttcgtatc gatgatttct cctgtctgat tattgtaagc ttttcctcct
    29581 aggacggtgt atttgggtgt cacaaagttc ccatttcgaa aagcaactac ttgatcatgc
    29641 tgagaagata ataagtctgt accaaaatga agataatctt tatcatcgat tcccaataga
    29701 tgtagtaatg tcggcaaaac atcgatttct ccaccgtatt catgattgac tgtcccttta
    29761 gtataaccag gcatatggat catcaatggc actcgttgca tctgtgcgtt gtcaaattca
    29821 tcccatgtat ctggatcttt accaagagcg cttgctaaat ctttattatc tgtattcgag
    29881 atcccaaaat gatccccgta aatcacaaag attgaatttt ggtaaatacc agattttttc
    29941 aaatacgtaa aaaattgttc caatgattga tccagataat gtgccgttcg aacataatta
    30001 tctactgtgc tattgccagt attcaaagat ggaaagtcga aattcttgtc atccgtataa
    30061 taaggcgtgt ggttggttac ggaaagaaat ttcgtgtaaa acggctgttg tagatgctca
    30121 agatattggg cagattctct gaataaatct ttatctaata tcccataacc taacgtttcg
    30181 tcggattcat caaaataaga tcgatcaaag aaattgtcat aacctaagtt tttatataca
    30241 tgatctctat tccaaaaact agctacattc ccatggaaaa cagcgcttgt atagccttgc
    30301 ttttgtccaa ggatcgctgg tgcggcttga aagacattgt ctgacccaag ttctgtgaat
    30361 aatgagcctt gaggtaaacc aaatgtgcca gtttccaaca tattttcagc atcacttgtc
    30421 tttccctgtc ctacttcatg aaagaaattg tcaaagctga tcgttgcttg attctggaaa
    30481 atactattta aaaacggtgt gacttcttgt ccgtctacct tcatattaat caaaaactgc
    30541 tggaaacttt ctaaatggag aacgatcaca tttttccctt tagcgatccc aaatgtttcg
    30601 ggatttggct ctgcataatg tttctttgta taatctaaaa cttcatcaat cccattactg
    30661 cttgcatgcg cgcgaacact gctagtcatt cctgttttga ttccgtcata aatagtatac
    30721 gcatcgattc ctagatattt gacaatatat gaacggtcaa atgttcgctg cagcaattgt
    30781 ggacggttgg cttcgctcag cgctagattt cctgaaaaaa taagccctga aagacaggta
    30841 acagcgatag ccatcggttt gccgacaggg ttgcttttga taggtatttt cttgaccttc
    30901 aaccaaacca gtagcccaat gaacacagcg atatccagcc agtagatgac atcatggggc
    30961 ttcatcaaag aaaaggagct tcctgacaat ccttgcgaca ctttcgaaaa gcctaataca
    31021 gatttgactg taatgaaatc tgtgaattcc cgataaaaaa taatattcaa gtacaacaaa
    31081 agcgtattta aaatatcaat gatcaaaaga atagctaacg ctggctttgg ctttttaata
    31141 tacaaagaaa ggccaaaaaa caataaggta gtcgcaattg ggttgatcca caagataaag
    31201 tactggatcg taccttccac acctaatgaa aaatctgcat agtaggcaat gatcgtcttc
    31261 agccagaaaa agaaaacagc tgtcaaaacg attgctaaac gattttggca caatttttta
    31321 agttgtgtca cgtatatcac ttctctctat tcacattttt tcttattttg ctcctgaaaa
    31381 atgaaaattt cctaaaaaag ttgttatctt aagatttttt tattctttct aaagattatt
    31441 ccgtccactt ttcacagcat aaaaccgctg cgatgtaagc gattaaacta atgaagagat
    31501 aaaagtcttg tggtgaccgc ttcactccac ggtattcaaa agccagtttc tcggtattcg
    31561 tacaaaaaaa gaggctgtga caaaattctt gtcgcagctc cttatttctt gatgcaggac
    31621 agctttttca caacttcttc cttaaacggt gttctcctgc caactcctcg gccacaagtc
    31681 acaatattta taaaacatga gaagctgttt tttgaaattg ttccttgtgg ctcagagtta
    31741 aacggcaggc tcaagacctc ttgatacacg gtgttcaatc agctgaccct cggtattaga
    31801 ttatgtcagg acgctaattt tacaacctct tggtaaacgg tgttcaaaag cttgcatctg
    31861 cggtaataag cccaaccaaa cgaaaaatat aaggagctat tttttgaaat tgctccttgt
    31921 ggctcagagt taaacggcag gctcaagacc tcttgataca cggtgttcaa tcagctgacc
    31981 ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt tgtttctcta
    32041 atactcaggt caaaacgctg atttcacaac ctctgttttt cattgtccat aggattgata
    32101 ttgtccttgt gatgactcat tcgtaataat tgaggcttga ttttcttcac ttcccgttat
    32161 cgtttgtcca ctgccagaat ctgaaggact tgttcctgtc gactcgtttt tttgagaaga
    32221 gacagttgtt ttcttgactt gttcatttgt ctttttccat tccgctaaac gatcggcgac
    32281 cacttttttg tctacttttt cagaataagc ggtgatcact tttccatttt tcaaacgggc
    32341 tactttgtcg ccatcatgag tcaaaagcaa aacggtcaaa tgcttgtctt taaattgata
    32401 ttgtctgaga gaaatcgcac taagtacgtc atcgatatta ataaattgat tttcttcttt
    32461 tccttttggc aaataaatgt ccaattcgcc tttttcgtaa ttggcagtta ttttatactc
    32521 cgcccaccaa taagttgaga attctttttt gaaattatct actgattctt tgcttgctac
    32581 gattttttct gtttctttct gagcaagatc tgctgtcatt tttcctgaaa atgctgcgga
    32641 taaaataagc agtaagaaaa aaccgaataa ccaaaagaga agaaacggtc tttttttcct
    32701 catgctttcc tccactccta tttaattttg actattctat tatatacaaa aaatgaaata
    32761 gaaagacaaa aaagttgaaa aagatcgtaa ataattgaac ttctttttca caaaatggta
    32821 agaatggaga atttcacgca tttgctctca actattcttt cttaagcctc aaatccgttt
    32881 ttatctgata cgtctttgaa ccaatgaccc gattttttga ttgttctttt tccatcttgt
    32941 gctaagtcta ctgaaataaa gccatatcga ttcttatatg cattggtcca cgaccagtta
    33001 tccatacatg tccacatatg atagcctaaa caattggcac cttcttgaat ggcttgatgg
    33061 acatatttca gatgagattg gacaaattcg atccgataat catcgtggat catgccatct
    33121 tctttgataa atcgtgcttc gttttctaca cccataccgt tttcagaaat aaagcagtcg
    33181 atatttccat aatgatctcg tacattgatc aaaatatcat agattccttg ttcatagatc
    33241 tcccatccgc gataaggatt cattttacga ccaggcattt cataattgtc gaaataatcc
    33301 tcaggcattg gaccgttttt agtatcgatt ggtgtttctt ttgcttttac ccggcgtggc
    33361 tggtaataat tgatacctaa aagatctact gtattttctt tgataaccgt caaatcctct
    33421 gcatggatca caggcatgag atcaagttct tttactatct caatcaattc acttggaaac
    33481 tcgcctttta cagctggatc aaggaatgaa cgattgaaga acgcatctgc tatttgcgct
    33541 gctttaacat cttcagggtt tgattcgtct cttggatagc ttggtgtcag attcaagatg
    33601 ataccaataa caccaccttg ctccatttca tggtaagatt tgatggctaa cgctgaagcc
    33661 aacgcttcat gatagccaac ttggatcgct tttttcatat ctgactcttc tggataatgc
    33721 catcgatata aataacctgc ttcgactgga acgattggtt cattatgagt aaaccatttt
    33781 tttactttcg aaccaaacaa ttcaaaacaa cttttggcat atttttcata ggcttcaacc
    33841 gtttctcggt tcaaccatcc gcctttttct tgcagataca tcggcatatc gaaatgatac
    33901 agattcacaa agggttcgat accgttttca atcaactcat caaaataacg atgatagaaa
    33961 cgaacggctt cttcgttgat tgttccagat tcatcaggta tcaaacggct ccattggata
    34021 gatgttcgaa atgaattatg cccagtctgt ttcatcaact gtacatcctc ttgatacttc
    34081 gtataaactt gcgaggtttt ttcaggtcct acttgatcaa agaacttttg cggttctttt
    34141 ttgtaccaat aatcaaaaat gttctctcct tttccatcgc ctgaaatcct tccttctgtt
    34201 tgtgggccac ttgctgcaga accccaccaa aaatttgctg gaaattgata ttttttcatc
    34261 aaagcacctc tttttctttt ttagttcgtt ttagttgatt ccatgtatga tattttccat
    34321 cacaatcact ttttcatttt cttcctcttc ttttttgatt cgttttaaca gctgttctgc
    34381 tgctcgttcc ccgattttat ctgttggtgg cgtgatcgtg attttcggaa ggatactcag
    34441 atcgttttta tctaaataat catagtgact gaacgcaata tccttcccga ttctgacacc
    34501 ttcttgattg aaacattcga tggcaccaat cgacatattg taattgctga caaaaatagc
    34561 agttgcccct ttttctaata atgcttttgc cccgtaatag ccgctttttc tagaatagtc
    34621 tcctgtaaag acctctaatt ggatcgatgg atcattttgg accgcttctt tggctcctgc
    34681 taaacgttct cttgctacgt agtctgtttg agtggcagca ataaatccga tttttttatg
    34741 tccttgttca ccatgatgag cgatcacttt tgctacactt tctcgatcat tcactaatat
    34801 tgtatcaata cctgctggtc cttctggaca attcaatgcg ataactggaa tactcatttt
    34861 tgtgagcatt tcaaatccag accactcttc ttcggataag aagacaatca gcccatcgat
    34921 cacatgcttc atcaggtatt caattttttg ttcaattttt tctggctgat cggcaaaccc
    34981 gcttaataat aagctatacc cattttcttc agctactctt tcgatccctg agacaacttc
    35041 cgacccaaaa cggctggaaa tcccgtttat caaaagtcca atagagaagc ttcgattatt
    35101 cttcaaccct ttagcaatga tgttttcttt atagtccaac gctgaaatcg cttctgctat
    35161 ttttttcatg ttcttttcct tcagttgctg accattcaag taacgggaaa ctgttcccac
    35221 tgaaacacca gccatcttag ccacatcacg gatcgatgcc atacattctc actcctgcca
    35281 gttacatttg atttctcttt cttgttgttc gattatgatg accgcattct ttgcatagtg
    35341 ttgcttgtca tcaatatcca tataactaaa gtcttcagta gagcaacttc ctctcactat
    35401 taattatact taaacaagta tttgaaccgg ttcattttta atatagcatt tttttaaaag
    35461 attgcaacac ttttttaaaa cgctttctga aagtggcgga ttttttgcct ttttaaaatt
    35521 ttattctaaa atttactcta tttgtgggtg ttttgtgcgt ttttctcttc catccgtttg
    35581 aagttttaca ttccaatggt ataatttctt tatcctatca aatgggggaa gtattttgaa
    35641 gaaattaatc gtactattta ttttgtctgc gggacttttg acattgactg gctgtgattt
    35701 gtttggcggc tctgaccaat cctcggacga aacaaccgat tcttctgtct taaaagcgga
    35761 aaaagcagat accaccaaca gtgtatatac gctaaaagta cgtaaagata tggatttatc
    35821 cgcgggacag ttgacattta cagataaaaa aatggaatgg acacgcacgt atcagacaca
    35881 aggaactgat tcttctgaat catctgaaga aaaaacagtg ctgacagata tcaagatcac
    35941 taccaaagat gacgaatata ttatttcagg aaaagaaaat aaaaaagaaa caacagtcat
    36001 atttacaaaa atcggtaatt accgtttgaa ggatgaggat ggcaacatct acagtctata
    36061 gtgccgtctg ttggatcttc ttttgtttct ccccttcttt tctgctatag taaagaagca
    36121 agatgattgt aaaggagacg aaatggatga tcgatagtcc tgattattgt acatgtaata
    36181 acaacaaaaa tatccataca gaatttaatg accaaggaag cttgagcata tgcgacaact
    36241 gtcacaaact agtcaaagat tcatttaaaa catttgaatc ttatcctgtt caaaattatg
    36301 taaaaagtag aagaagataa acaaatccaa gcaaaactca ctatggctga tttttatgaa
    36361 cttcaaactc agcttcttcc tttgatcaag cttcatcagt aaaacaaaca gtggatcatt
    36421 tcagtttaca aatcaaagag taaagattta tttatttcaa atatttgaat ataaaataac
    36481 caaacgatag aaaggcttat tctacatcac gtagtaattt ttctttcccg tcgtttggtt
    36541 ttttattttt agcctaattc ttgacctttt gcatgctggt tatccgtaaa atattttcca
    36601 gcaggctttc cttccaattc agctaatttt tcttggatct gacggatcac cttttttgca
    36661 tcttctggat tttctacaaa atcgaattta tccccatcca cttgtatttt aggacataca
    36721 tcaaaatctt cataccattg attatagcgg gtgttcaacg tttcataata ggtatataac
    36781 gtctcatcgc tttctagctg ttcatagtca cgcccacgtt ttttgatacg ttctagcatc
    36841 gtgtccaaag aaactttgat atggaccatc aaatcaggcc gtttttttgg agcaacatca
    36901 tctaactcgt ttagcatcgt atctaataag ctatcgtact gctgtacttc gatatccgtt
    36961 acccgaccta aatcagcgtt tagatggaac aacaggctat cttcatagat ggatcggtct
    37021 agcacattgt catcgttcac taaagcattt ttcattgcta aaaatcgctt gttcaaaaag
    37081 aagatttgca ataaaaaagc gtactgctca ggatttgaat aaaagagcgg caatacttcg
    37141 ttatcttcga cattttcata aaatggttta gaatcaatct cttttgcaag catatccgtc
    37201 aaactgctct tacctgcacc aatcgttcct gaaatcaaaa tcactgacat acaacccttc
    37261 ctcttctata agtactcgcc tacgtaagtt tcaacaggca atgtttcaaa atcatattca
    37321 cgtacagctt ggtctgattt taaatacgta tggagacttt gtgtaatcat caagttcgta
    37381 ggtaccgtct cttcttgtac aatgatcatc ggttttttca acatagttgc cacacctaat
    37441 tcgtaagccg ttcctggatc gattgtttga tgctcaaagt caaggatagc aacaacaaat
    37501 tctgcatttg tcagttcttc catatctttt tcgtatactt cctgcgccca tccagcgctg
    37561 aatagttcat aattgctttc ttggtgatga cgtggagagt agaaacttgt gactgttttg
    37621 ttttcctcca acgctttttc gatacgactt actcgatcga tttgctcctc tgaaaaaaat
    37681 ggtcctgcta aatatatttg actcattatt ttgcctcctt caataataac tgatttttaa
    37741 tagatactgc tcgtaattca ttgaccagtt ccaatggatt gttggaaaag attacttgat
    37801 ccaaccattt tttatccata aaatcctctt ttgcaaaagt ttctaataat tgttgcaagc
    37861 cgctgtaata accgccaata ttcaatattc cgattggctt gtcgggcgtc agaccgattg
    37921 ctatccaaga aagaagttgt gagaattcct ccaatgtacc tagacctcca gggaaaacga
    37981 ggacagcatc tcccttttca aataataata cctttctttc atcgatcgtt tctgtaggaa
    38041 taaatgtagt aacatctttt ccaggcaatt cagtttcaaa aagcccattc ggatagatac
    38101 ctgtgacttt tccgttattt tccagtactg ttttactaat cactcccata atcccggagt
    38161 atgaaccacc gtaaaccagt tcgatttctt cttgtgccat gtattttcct aacgtttgcg
    38221 caataaattt gtaactttct ttattaccaa aacgggaacc gcaaaaaaca gtaagtttca
    38281 taaaaaaaca ctccctaact caaaagtcta tcttcattct acacgtgttt ttttaaaata
    38341 aaagactaga ttttgtagtt ttttagtggt atataggata gacgccacta tatatagtat
    38401 ttagaaaaaa atcatttttc agccatttta tagataaaac aaaaataaat aacgtgtttt
    38461 catcgatatg aaatgactta cttatagaag atactgggat ttcgtcctat atgccaataa
    38521 cgtgtattat tttaaacaac aaatacttgt ttcttttatt aacgaaaaaa tcattttgtt
    38581 ctcgtgttat gtttcactga taaatgatgt ttctctaaat aaaaaagccg acgaactaaa
    38641 cgatcaaaat ttgatcattt ttgttcatca gcttctccta aaaatctttt tgttaacgat
    38701 aaatagctgg atttgtaaaa atatcacttg aatcgtcact gctggaagaa aattcagtga
    38761 taaccgcacc tgttgcgcct gcctggaact agtgtttgat attgggctcg aacgtgtact
    38821 gatctctagc atgaagaata atttcttttt ttactgtata ataactttct ttcctttttg
    38881 gaatagtaca ggaaagtttt tttgtttcct ttccttcgac ataaggtata ccagaccctt
    38941 tcgacaacga aaggttctca tttttccttc atcgtcattt caaggagggt gccgatgctc
    39001 tggacagttt cgatcgctcc taaaccaaaa tctgtatatt cgattctttc taactctgat
    39061 tctttcatac cattcctgtc tcaaggtaca tctattgtac ttttttcttg taatccattc
    39121 tgcctctcct aactaattgt caaatcatcc caagatatgt cttcttcctc tttttcttct
    39181 tggatgattt ctgcattcgg atctactggt tttttcaata ataaaatggt tattcctgtg
    39241 acaaaagaac cagctaacaa tgcaccaatg aatgcccatg gtctggtcat cgtagcgact
    39301 gcaaacattc ccgatgccgg aatacggcta tctgcgcccc aaaacatgct taatccgcca
    39361 cctactgtcc caccgactcc cgttgctatg acattgcgtg ccaagtcgtt caatacgata
    39421 gggaaacatc cctctgtgat ctgacagatc cccataggaa aagcggtctt caatgtatcg
    39481 atttcttgac gattgagtat atttttacga atgattttcc ctaagaaata agcgatcgtc
    39541 aagccgaatg gggttaccat cgaagctaaa atcaatacag tgattggttc atagattcct
    39601 tctgaaaatc gtgccacacc cccttatcca gaataaatgg taatccagaa acagccgtgt
    39661 atctgcggta ataagcctaa ccaaacgaaa aatatgagaa gctatttttg tttggctgtt
    39721 cttattactt gatgcagggc agctttttca caacctcttt ttttatttat gtttcataat
    39781 caatatggta aggatgcagc tccgtatggt agaccgcctc cgaatattca atcatttccc
    39841 caatttgcgt agacgatttc cgtatccgtt tgatgccgat ctgtgcgtct gttttcagaa
    39901 ttccttgttc ttcttctgtt aaaaatactg ccgagaaatc atcagaaaat gagtcaatag
    39961 tatatccttt tttcgtcagc aaacgataca aagattcttt gccaaattct tctctgctga
    40021 attgcatcat ttcttgtgga agataatgaa caaaataaat ataaggctga ttgttcaaat
    40081 aatataagcg cttaaaacaa acagcttgct caccgaaaaa ggaaaacaaa ggatcttcct
    40141 tctttatatg gaccaattgc aaatccagcg tttctttccg gacttcatat cgggagttct
    40201 ccaagatttg cgtaaagctt gccgctttgg ataatcgatt gtaaggacga ttgcttagaa
    40261 ccgtcgtccc acgaccactt ttctttgcga catattcatc tgatgccagc agttcgattg
    40321 cctttcggac agtgattttg ctgacttgaa acagttcttc taattcactt tctgtcggca
    40381 acatcgaacc gactggatat tttcctgaga aaatatcttc tttaatttta tctgcgactt
    40441 ccaagtatag tacacgtgtc cttttcataa cgtcaccctt tgctttacta ttactaaaag
    40501 aatagcacat aaaaaataaa aaaagaacac aaatcacatg tgagaagtgt gttctttttc
    40561 attcagctgc tttaattaca agtttacgcc atttgaggca attacttctt tataccaatc
    40621 aaaagatttt ttctttgatc gattcagtgt cccatttcct tcatcgtcta gatccacata
    40681 gataaagccg taacgtttac tcatttctcc tgttgatgca ctgacaagat cgatacatcc
    40741 ccaaggcgta tagcccatca aatctacacc gtctgctact gcattagcca tcgcttcgat
    40801 atgacgacgt aaataatcga tccgataatc atcaataatc gtgccatcct cttccatatg
    40861 atcaatggct ccaagaccgt tttcaacaat gaataatggt ttctggtaac gattgtataa
    40921 ttcattcaat gcgattctca gcccttctgg atcgatctgc cagccccatt cacttgcctc
    40981 aagaaacgga ttttttactc ctcccagcaa gttcccttct gaagttgctg cttgtggatc
    41041 agtctcattg attgccgtag acatataata actaaatccg atgtagtcca ctggatattc
    41101 ttttagcaac tggaagtctt tttccgtttg ctctaatttt tccggatcga ctccatattt
    41161 tttatgggta cgcgctgtgt atgcagggta ttctccacgt acttggacat ccgtgcagaa
    41221 aaaattgaat tcttggtttt ggatcattgt tgctgcctga ttgactggat tggcatcgat
    41281 gctgtaagtt gttgcataga taatcatgca gccgatttgg atatccgaac gcaattcgtg
    41341 gccgattttt acggctttgc tacttgcaac gaattgatta tgccatgctt ggaaaatatt
    41401 ttggtactct cctgctccat tgctttttac taatccttga cttaaagctg gaaagtgaaa
    41461 ggccgaattg atttcattga aagtcatcca atatttgact ttactgctgt atctctctaa
    41521 tactgtctga gcaaatcgtt catagaagtc gatcagtttt cgatttttcc agccaccgta
    41581 ttcttttgcc aaatgaagag gcatttcgta atgagaaatc gtgatcacag gttcaatatc
    41641 atattttaag cactcatcaa tcagctgatc ataaaattct aatcccgctt cgttaggagt
    41701 accttcgtct ccatttggaa aaattcgtgt ccaggcaatc gaaaaacgat aacatttgaa
    41761 tcccatttcc gcaaacaagg caagatcttc tttgaaacga tcgtaatgat cgattcctcg
    41821 atgattcggg taaatatatt tttcttgatc aatcgtccag tcaaattctt cactgccgat
    41881 aatcgcaaag cgctgcttac ctccaggcat agcatctgca acggatagtc cttttccgtc
    41941 tcgatcataa gccccttcta attgatttgg cagcagttgc tccaccccat aaaaattttt
    42001 ctgaaaaacg tgattgcatc ctgatttcct ccttatttta caattgccag aacatcttcg
    42061 tttgcaataa tctctttttg gtctaattca agtatatcgg caaatgcatc agtattcgta
    42121 atgacaactg gagtgattac gctatagcca gctgctctaa ttgcttcgat gtcaaaacga
    42181 atcaataaat ctcctgcttt gacgagatcc ccttgtttga ctaagatctc aaagccattc
    42241 ccatttaatt ctactgtatc catcccgata tgaatcaaaa tctccgctcc gtcagtcgtt
    42301 gtgatcccta cagcatgtcc agttggaaaa atagtcgtga tctctccgtc tgcaggtgca
    42361 actagttctc ctacttctgg atcaatagcg ataccttttc ccatcacgcc agaagaaaaa
    42421 acttggtctg gtacttcact caatggcagt actttacccg ttaaaggact ttttaaggta
    42481 tgccgtgctg aagtaatcgg ttctcctgca ttcgcatgtt tgttttctaa ttgattgtct
    42541 tgtgtttgtt cgtcaaatcc taaaatcaat gtacctacga atgcaagaac aaaagcaatt
    42601 cctgtagcta ttactgctac tgtcacattt gactctacac catccaccgt attaatgaaa
    42661 gtcggaatcg tcaataagct gaccaaactg ctggagaaag cttttactcc ggaaaatccg
    42721 ataatagctc caccaatacc tccagaaata caagcggcaa tgaatggttt cttcaaaggt
    42781 aatgtcacac catacacagt tggttcagtg attccaaata acgaagtcac tgtagaagaa
    42841 atccctaatg ctcgaagttt cgtatctttt gttcgcaatg ctacagctaa agcagcccca
    42901 ccttgtgcca agatggctgg aagaagcatt ggcatcaata catcaaaccc atattgttcg
    42961 atattcaaaa acatgatcgg tacgaatccc caatgcatgc cgaacatcac gaatacttgc
    43021 cataaacttc ccatgattag acctgctacg attggactaa atccataaat cgagttgaag
    43081 agaccgccta aagcattacc ggcaaccgtc ccgattggtc ctaaagcaag aaatgttaat
    43141 ggaaccatca ctactaaaac gacaagcgga actaaaatca tttgcagaaa ttgcggaatc
    43201 acttttttta cgaatggctc taatttactt tgaacccata cggctagaat gattggtatg
    43261 acagaagaag tataaccaga tggtgaaaga atcactggga tcccaaagaa actgatagct
    43321 tctcccgcac cagcaactgc tgtgatagct ggatacacaa gtgccatagc aattgctact
    43381 gctaaaaact ggttggcttt gaacttttta gctgctgtaa aagcaagcat gacaggtaag
    43441 aaggtaaaga caccatctgc tgcagcaaac aatatttgat aagtaccgct atcagctgtc
    43501 agccagccca tcaccgttgc caatgataag aatcctttca ataccccggc ggctgccatc
    43561 gcccctagaa aaggtgtaaa tatactagag ataatatcga tcagacgatt caaaatattt
    43621 ttggactctt cttttccatc ctccgaaact gcaagacctt cctcatccac gatcgattga
    43681 taaacatctg ctacattact gccaatcact acttgatact gaccgccact ttgtacgact
    43741 tggatcacgt ccgggtcttc ttttaacttt tgcgtatctg ctaaagattc atcttttaat
    43801 ctgaatcgca accgcgtagc acaatgtact aaacttttga cattcttttg tcctcctacc
    43861 gcttcccata cacgacgacc aactgcttga ttatccattg ttttttcctt ctttcttttt
    43921 tatttaaaaa ataaaaaccc agattgaaaa aaacagtcac aaacattcgt gaacctattt
    43981 tttcaatcca ggttttgcct gccatacagt aacaatcctt atgattggat gctttttttc
    44041 tcacttacta ctctttgaat atgaatcgtt aaataaatct gctctgcgat ccccatttcc
    44101 tgtttttgcg tttgtcgaag atactcattg atccgttcga cacaatgaaa cgcttttgga
    44161 tactttcctt gaactaatgc gtagagaaat tcatcttgct cgtcagatcc ttcccctttg
    44221 agataacgct gggcaaaaaa ctgcagatga gtaatgatac gctgataatt caaagattct
    44281 tcatcgaaca cgatgccgaa gaatttactg atgatactca gtatatctct taccattgtg
    44341 gtagcggtca tcgtcacttg catgtcttcg tttccttgtt ggctattcac aaaatgaaag
    44401 gcaataaaac cggcttcatc ctcagaaagt tccacacccg tcttttgttt cacgaacaaa
    44461 agagcctctt tcgctgcttg atattctttc ggataaaatt tttttgtttc aaataataat
    44521 ggattaggca gttggatatt ttcttttgct cgtgtgatcg cataatgaag atgatcggtc
    44581 aatgtcagat aaatattagg cgaaaattca acttttagtt tatcttcagc cagttcgact
    44641 acttgtttga cccattcgat ctcctctgcc ggaatatcag ccatcagctg ctggaattgg
    44701 tttttagcaa aagaatctct taaacaaatt ctttttggac cgcttctggc gaaatctcgt
    44761 ccccaatctt tttttgaaaa gctagtcctt ttcccataca aacgacttct tccccgaatc
    44821 catttttcga aatgacgaca ttgttattca aaattttatc aattttcatt ttgcttcgcc
    44881 ctctcaagaa aaataaaaaa acctagaatt cgcctactgt ttcttagctg aattctggtt
    44941 ttgcctgccg tacagtaaca atccatttct tattcaaaat catcatacca tcgaattttt
    45001 atttatgcaa gccttttcat ataaaaaata aaaaaactgg aacacaagtc tatctagaaa
    45061 acaaccaaat cagagatgca cctctttgcg tttctctttt tttcagcaaa ttggtttttc
    45121 cttatcgatt catatccttt ggctgttttt aatctgtaac gacttatgtc ccagtatcct
    45181 aaaatgtttt tgtctctaga ttgaaagcag atctcatatc atctgtcgca tcttttatcg
    45241 atgtaacact ttccagttct ccttgtacaa ctagtcgcgt gacggcgtcc atgtcgccac
    45301 aagtaattag tgtgacaatt tcttttccct cgacttcatt cagtaattgg gtatctgtag
    45361 gagcaacttt ttctttaaaa aatgttttgt atgtatacac attttctaaa tctgtcaaat
    45421 agatcttggc acccatctct aaattttcta gcggtgtaaa cagcaattca gggttcgttg
    45481 cacgatggct tgctaaggca taatttcctt ttcccatttc ttgatctgga gataatgttc
    45541 ctgctccgta aagtagtgac gtattatcca agcctttgaa aaccggtaaa ttgattgaaa
    45601 ctgaagggac tgcgatacta gcaatcactg gtagatctgt tcctctcatt tgcgacctca
    45661 tgaccccttc tgtcgtcatt ggttctaccg catcaaagtc aaaactgaca tctttatcgt
    45721 tattcttttt cagatcttct tttgttacat tcgctatagc atatttatct cctgtctctc
    45781 tgacaaaata atccttgatc tgttcattga aaatcaaagc tagtcctact aataacaaga
    45841 ggaacaagag gatattgact agccatcttt ttgcttttcc tttttttttc attttctctc
    45901 cctccagact cattttactg tttttctttt gctctttcca acagccgaat gacacatttc
    45961 tacaactctg tgtatttttt tcgtacacct gcgctttttt ctacaggata tttcaaatta
    46021 tttttgatca atttttcttc aatgatctca tctagatcca ggtgaaggtt gtctgccatc
    46081 atgtatgaat agatcaatac atctgccagt tcttctttga ttcgttctaa ttgtgtttct
    46141 tttacttctt ccggcgtttt ccattgaaaa agttctaaca attcagatgc ttccaaagaa
    46201 atagagatag ccaaatcttt ttcgttatga aattgtcgcc aattacgttc atctctaaac
    46261 tggttgactt tttccatact attcatttgc ttgccttctt ccaatcactt cttacttgat
    46321 taatcatacc atttttttac ataaaaaata gatgatgctt ttaaaaaaac tcctgttttc
    46381 ttttatttaa aataaatgtc atagaaaatc aataatttag gtagccacca tgtgtatgca
    46441 gtagcgtgtc ttcttccctt gaggcttttt gtttttcgat acgttcttct tcccaaacag
    46501 acaacgctac tagaatctct cttaatgatt ttccttcttc ggtgagcgag tactctactt
    46561 taggcgggac ttggttatag gcttttcgat ggatactttc atcttgttct aactctctta
    46621 actgctgggt cagcattttt tttgtgatcg tagggatttg cttgcttctc cacgcctaaa
    46681 ataagcgata ttgctcttcc ctttatctgg tgtaagcaaa gcagttagca ttttgacgat
    46741 cgtgggttcc gcttttcact tcttatctac ttagtatcat gaagtatact ttcgtactaa
    46801 tactaagtag cggaagtgtc aactactttg tttaactaca tagcaaaaga aacagaaggg
    46861 tgacaacggt catcacgctt ctgtttcttt tgaatatgct gtgttgttgt ctctatctcc
    46921 gtgtagactt tcctcaaact tatcctttga cagtaagtca gtaggctgat ttgctctttc
    46981 tagatgccag atacatttct acaaaaaaat agtgattctg ttttgaaaat tcgattttta
    47041 gttctgcatt ttcgtaaaca tccaacattt ttttcgcact gtatagacct aacccgccat
    47101 tttttttaga ggtttttcct cttttgacca tctccgatag cgtcaaattc gttggatttg
    47161 ccttgttcgc tatactaaaa cgtgatccct ctttttcttc cagcagattg atcgtaatcg
    47221 gactctgatc ggctacacga tgatcgaatg cgttagaaat aaaaatagat aaacagcgaa
    47281 taaaaacaac cagatcaatc gggattgttt tcacttcgac aggaataact acttggatcg
    47341 ggattttctc cgattctgct ttttctagaa attttaaaaa gacacccctg acagctgggg
    47401 atacaatatt tgttagctgt tgtatttgcg gtttttcaaa aatagctgca gaatgatctt
    47461 ctaatatttc taaaaattcc aacgtttctt ttttattttc ctgaagagta atttttaatg
    47521 aaaacagtag acttttataa tcatgtttga attcctctag atgatggtaa tattcttcat
    47581 ttatttgata cagttgaagc gattcctgat gttgtctttc ttttacttgg aaactgatca
    47641 acataatgga aaaaaacaaa gaaaaaaaac tgatgactat cgacaaaaga gatagaagca
    47701 gataattaga tgagcggaag tgaacacttc ccaataccaa gtaaatcacg ccccagctta
    47761 ataaaataca aatacctcca aaatagtgtt cagttggata agtaaaaagc aagttgagaa
    47821 atctcgtctg tttgtctata ctttttacta atagatagaa aataaatgcg ataagtagtg
    47881 caaaaaaact tgctgttcca agatgtctct ttcctaaata atccatcaga tcaaaaacca
    47941 gaaaaaagct gagtccagtg atagcaaaaa aaagattact gatcaaacag ctgataaaca
    48001 ggtttttcgt agtaaaataa aaaagaaaca tcaataataa gccaactagg taaggaaagc
    48061 tcactttagg gataggaagt aaaagtgtca ccaccatcaa agctatacaa ccaaagctgt
    48121 tttttactag cagttgtttc gaaaagaata aatagatacc taaatctaaa atcaaagtaa
    48181 aggtcaaata aagtgtcact gttgcgacca tcttattcct ccattgtttt gtttcaaaat
    48241 gtacacatat ttttttaata ggagcctgca tatgaaaaag tattttatca tagaagataa
    48301 ccagtttcac agcgaatgga tcatcagaga attggtcaat catcatatcg agaatatcgt
    48361 gcagctcact tctatctctc aaatcaatca gttgatccag ttgggcacta ttgataatca
    48421 cgatgttttc tttatcgata tcgacttgaa gcaatcactc acaggtattg atgtcgccga
    48481 acaaatacgt aaaaaaaatg cacatagtaa tattgttttt ttcaccgctt atacgaattt
    48541 tgcagtagag atcatcaatc ggaaaatcct tccgattgga tatatcagaa aagacaggaa
    48601 tttatctgaa caaattcgtc aagtgctaga acagatcaat tggaaagaac agcagatcgt
    48661 aaatgtcgat aaaatcttta ttgatcaaaa aggtggaagt ctcgtcctgt atcctcggga
    48721 aattttatat attgaaagta tcaaaggttt gaaaaaccaa gttatggtca aaacaactac
    48781 agaagataaa ttagtgaata cttctttaaa acaattgaag acagagttag aaaagtatgc
    48841 ttacttttta cttttaaaat cttactgtat caacttatcg caattgcaga aaattgattc
    48901 tgctcattat gtgttagaat ttttcaacgg tgactcctta ctcgttggtc gaaagatctt
    48961 tgaaaagaca aaggaacgtt tccatgactt ccaaaaaact gcttcgagtt gatgaataag
    49021 agctgagacg taagcatagc agatttcagg gagtgggcct tgaatcggct ccactccctg
    49081 aaatcgttga tatgatttta cgcttcctct tctgtaggag catctgttaa cgaccatgtg
    49141 aatgttgaaa cgtagttgtc tacagcataa ttggatacag gaacaaataa ttccactgat
    49201 tgtctccctt gttccacatt ctctcctaat gaataaatcc atgtgccaat cccttcattt
    49261 gctcctgcag ttactagatc tactgcctga tctgctggga tttcgattcc ttcagcgcca
    49321 gttccagaaa cggtagatgg cattccactg ctattagttg cgctatttcg aatcacggcg
    49381 tttttgaatt tcacctttga accagttagt ttattcgtat cagatgttgt accaataaat
    49441 tctgttcgtt tgactgataa tttccaaccg gcataatttc cgcttttatc cgttacttgt
    49501 acgaaattct gtacttgtgt ttgtgctcca gtactgtccg ttccgctttg taatgcagca
    49561 tatactgttt ttgctgtacc taacttgatt gttccaaaat caagatctgg agcttggtca
    49621 atcgtcagta atccggatgt tccctgattt ggttcgtcag gtgtaaaagg agtatcagga
    49681 tcatttggat caacaggagg aactggaaca acgtcttcag gatttgcagc atctggtttg
    49741 gtcacagaaa tcgttccttc tgtagtggct gagctcttat tctcagcaaa aacactttgt
    49801 gtacataata atagacttcc agctagaacg gtacttaatg caattgtttt tttcatttct
    49861 ttttccttct ttcttttaaa ataaataatc cagcaaataa gccaataaga atgactccaa
    49921 caagtatcag ccatcgccag tcaaatgttt ctggctgatt ttttaaatca atatcctttt
    49981 cattcaattg gtccgctgca tcatcagtta tttcaaaatc ggtatggaga ttccagcgtt
    50041 tttctttcca agcacccttc acaaccgctt gataatgtcc cggagctaat ttttttcctt
    50101 ctaatgggac aagtaaatca aaatttgtat tgggtgctac atctattttt tcttttttta
    50161 ttgaaaggta aggctctttt gtttcttttt tgtagatttc aaccgatgta gtcaagccga
    50221 acatataaga agcatttgga ttttgaagat tcgccttaat cacatttctt ccatcgcttt
    50281 gatccgcata agcttttttt aatttcaaat ctggggaaga ctctttttcg ctatttcaaa
    50341 tcaagattgc tttcacttga gaaaactgat tgacgacacc aactgtactt ttgttagaaa
    50401 cgttctcttt tttttcttga aacgtgatcc ctcctgcgac cacaccagcc agctcttttt
    50461 ctggcgcttt cagtgaaagt gtctcagtga ccgcactttg aggaggaaca gttatttctc
    50521 ccactgtttt tgctaagttt ttcatatcat aacttaatgt ttcatcaaat ttactttttg
    50581 attctccata ttcgatcaca ccgtttgaat tcgtcgtagc ggagtggatc aatgtctcaa
    50641 ctgttactga tttatctgtt cggttaaaga ccgtgtaggg gatttcctgt gttttcccag
    50701 gctccatcct tacatttata tatgttttgt tcttatcaat ctgattagcc ggtaattcaa
    50761 aatctaccgc aaaattgaat tcggaggcat ggacaggtgt ctgccaaagg atgaatccaa
    50821 ggagaaggat cataagtaaa gagcagttgt ttcgatgact tttattccat attcgattca
    50881 tcaatcatcc tccttgatct ttattctgtc ggcgcatctg ctaatgtcca tgttatctct
    50941 gctgagtaat taccagctat ctgattttct ttggttaaga caagtttaaa cgcccgaccg
    51001 ttatttaaat attctgaata atctgcttgc acattcgttg aattttgtcc tctgacaatt
    51061 tccagttctt cttcattcac taattgatac tcctctcctt tcttgaaata taggacatcc
    51121 tgcatagaaa atcctgcatc atttgtgaaa ggctgagata attttatcgt taagatccac
    51181 ggatttttcg tttctcgctg atcataaatc cataattttt cctgtatatc catttggcca
    51241 aatgcttctt gtgtcaaacc agttgctttg atctgaccaa aatcgagttt ggaaggggca
    51301 agaaatgaga gaccaccttc tactacgatc ttcgtagcag gtgcaaaagg cggggcatca
    51361 tgataaacaa ctggcgtatc acttggattg tgattcccaa tttcatcgtt ggtacttggc
    51421 ttgttctgca cacccttagc agtagcttct cctgcttggt cgtttaatac aatttctaat
    51481 acatctcctg caaaaagttg attttctggg atagaaagaa caaattcccc tgtatcatca
    51541 atagttgttt ctgacaaaac agcttgattt tttttcaatg aaaccaaggc tcctgcttca
    51601 cctgtacctg tgatcgtgcg agaagctgca ttgatcaatg tggtacttaa attagcaggt
    51661 tcaggaggaa tcacatcgac tgtcgttttg gcagagtcca gttctgtcac ttcttggcca
    51721 cctcttactt ttttagcagc aacaacttgc acttgatcct ccgtttttaa tctctcatca
    51781 ttgggtactt gaacttcgaa caagccgcct tgttcgcctt ctccccatgg gttatatcct
    51841 gccccttcat tttcatctgt ttgtccttgc gtgagagcag taatttctac agatgatttc
    51901 gtcgtatctg cgtaagtaat acgtaaagtc acttctactt cgcctgtcca agcatctctt
    51961 ggctttgcct cgacaccttc gggaacaacg acatgcccat agattttttt atctgcattc
    52021 gttggcactc ttaaggattc aatcatcggg agctgattat tggcactgat tcgattataa
    52081 tttttcattc cggcacctgt ctgagcaaat tcatttgtta aacctgcact agggcttgat
    52141 acgaaattgc ctaagtcggt cccattgatc gataagtctg tcatatcaga aaaataatcc
    52201 gggtcttttt caaagttatc gaatgttgcg cctgtttttc gccataaagc gatttctgaa
    52261 tgggcgatct ttaaagaaga atctccattt ccttggaata cccagccgcc tatgccattg
    52321 gtctcgcttc caatccgttt gttttggaaa tcaaaatagg taggagattc taagtccaca
    52381 ttcaacacat ccccactgat gatgccggtc ttatcttccc ctgttttccc gaccatgact
    52441 aaataagttt tttcacctgc cgtaaaattt aaatcaatat ctccagttgt atctacagtt
    52501 gctccggaat ctgcgcgtat atcgatattt gatttttctc cagtgactgt aaaatcagct
    52561 gaacctggac tttctagaaa accagaagcg tcataaaatt ggatcgcttg atttccttga
    52621 ttgagtctgt tcacgtaaga tttgccatca cctgtatttc ttaccctcaa tgagcctcca
    52681 ttggttactg tcagcttttg cgtaccattc tcaaaacgaa ctgcgctgga acgcccactc
    52741 tgcttatcga tgtcgataac tgatccggct ccttctacga tcaaagaaag gccttttcct
    52801 acaaaacgca tcccattgtt cccgggttga tcgtcatctc cagccatttt gaccgagatt
    52861 tgtccaccac ttgatacatg gatttgacta gaatctcctt gcaagcgaaa tccgcccgta
    52921 gttgctgtat tgatggtgat tttcccacca ttcgatacag tgactttcga tcctgaacct
    52981 ctcatttgga tgattccgcg attgttgtca ttggtaatat tgatctttgt atttaccgaa
    53041 aattcgcttc ccgaaccact gacttcaaac atgacattac caggtagcgt atcgactgcc
    53101 tctccttcat cgctaacgcc atctgcccga tcataatcaa gagagacctt tgaaccgctt
    53161 aagatatgga ttcctggcgc tgtttttcca ctaccagtct catctcctga atctagaaaa
    53221 ccgtagaatt tccctagata cggtccataa agttgactac cattgatcac attcaattga
    53281 tagcttctac aaaaataggc tttacccgga gcggcattca gtccttcctt cactggttgg
    53341 acatccaaca caccggaaac accatctaat gtgacagttg cacgaggagc gtaaatcagt
    53401 cctaatttgg acccatcata caaatcaagt gtcccggtaa attttatttc tcccgtaaaa
    53461 tgatatctgc ttccccaaaa atcggtcata taagcaatga taatggcatt tccatcgata
    53521 tttggtgtca atccacctgg atgtgcagct gttcctttaa aattctggaa ctcgatcgac
    53581 tgaggtatct cattgatata aatatggtgt gtgccgaaat tgtgagcgaa tccaccaaaa
    53641 tcaataacga tatctcgttt gatctctaat tccctgtcta aagtcaaagg ctgaatcagt
    53701 cggatcttag ttactgattc gtctgcgaga agctgcgcca gttcttctgt tgtggcagct
    53761 tcgctgtacc catccgctga aacagctctt gccagtgccg cttcactgct atcagacgtt
    53821 tgttcagcta cttctgaggt ctcacttgtc ttattttctt cttgcctttt attagtagaa
    53881 gcctcacttt gagattctgt agtttcagaa gtaatcgatt cttctgaaaa agtagtcttg
    53941 tcaaaacttt gattctctga ttgcgttgat tcgtttgttt tctctacatc ggcaaaaacg
    54001 gatgtcacca tcaagagagg gaagacaaac aaaatcgacg caatcagctt ttttacacat
    54061 tgattcattc tccaccatcc tctctgacgt tttgacaatt ttattttatc gttttaatct
    54121 atttccaatt gtactttcat atttaaaata tgtattttta tggaaaaatt tttctattag
    54181 gtgtaaattt cttttttgta caaaaaaaag gctgtgacaa aagtcttgtc acagtccctt
    54241 atcccgaaca agcggtgttc tcccgccaac tcctcggtca caacctccat tttaacaata
    54301 aacctgtaaa tgtgagggca atactttgat tgtcacaggt aatttatccc cttcatctcc
    54361 atcaacattc gtcgtcaatt cttcctcatc agctaatgac acaactaatt gctcacaagt
    54421 aaggtaggct agatttttcg tagattcatc tactcctttt aataggtctg gcaatgtttt
    54481 aagcgtatcg atcaaagaag aatcttttaa ataaaccaaa tggagcttac catcatccac
    54541 ttttgcattt ggaagtaatg tttcaaaacc gccgactgag ttagttagtc ctatcagcaa
    54601 ggtactgctc tcaatttctt ccttctttcc atcaacttct acgtgaaacg agtaggattg
    54661 tgtggaagct aactgtttga ttcctgacat gaaataagct agttttccaa atttcgtctt
    54721 cttctccgca tctacatcat tgattgattc agggatagag ccaattgcga cgacattcat
    54781 aaaatagtcg tcatttattt ttccaatatc caatggcttg actgattcaa tcgaaaaatg
    54841 attgatcgct tcctcaggtt ctagcggtat ccctaatgct cgagccaagt cattcaccgt
    54901 acccaatggg aaaaatccga aatttggccg atgttcttgt tcagcgattc cactgattcc
    54961 ttcgttgact gttccatctc cgcccatgac aaacacacta tgataccctt ccgtagccgc
    55021 ttcgcgagta aagttttttg catcccctgc tttttttgta tgcaagacga ccacttcatc
    55081 aaacaccgat tccaattttg ctatcgctaa ttgctcaaat tcctttgctt gttcaccgcc
    55141 tgaactgggg tttaccacta ataaaacttt tttcatcact ttctttccct tctgattgat
    55201 ttctttaata taacgatagc ataaagaaaa aaattaggct gtgatgaagt actgttcatg
    55261 aaacattcat ttattttttg acaagataaa acatccatac tatgaaactg aggaaaatta
    55321 aaacaatgat ataggaaata aaagaaaatg ataggcattg tatacctaat aaagtaaaaa
    55381 tcttaggtgg cagataaaaa cacaaaaata gcaagagaat gtaatagcgt ttcttccact
    55441 ttttgttatc agaccttata gcgatcagag gaataccaaa tgcataactg aaaaactctt
    55501 gatgtactgt taatatgtca cggccttgaa taataaatgc gacaatcccc gctataatta
    55561 gtgtgcctaa caccaaaacg gaaaattgat gaatatattt tatatacaaa tgatccattg
    55621 tacttcctgc ctttttattt gtgagaaaaa caaatccgta tacgtgaata acttctagaa
    55681 ataaaagaaa tttgcaaaac cactccattt atctacttct acgtgcattt tttgatattg
    55741 ttttctttat ttaagattat acagaaaaat atctagggtc gctggattct aagtaaaaaa
    55801 aatttttaaa ataaaaagaa ctaaatcaag tagtaattaa actactgttg atttagttct
    55861 aataaaaaga tt
//
LOCUS       DAFLWZ010000014        48300 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000014 DAFLWZ010000000
VERSION     DAFLWZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.014"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1V38_000857"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1V38_000857"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBN1315424.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1V38_000858"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1V38_000858"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBN1315425.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="L1V38_000859"
     CDS             complement(2298..2960)
                     /locus_tag="L1V38_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1315426.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="L1V38_000860"
     CDS             3144..4790
                     /locus_tag="L1V38_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1315427.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="L1V38_000861"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="L1V38_000861"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1315428.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="L1V38_000862"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="L1V38_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="L1V38_000863"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="L1V38_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="L1V38_000864"
     CDS             complement(8939..10018)
                     /locus_tag="L1V38_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1315429.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="L1V38_000865"
     CDS             complement(10121..10561)
                     /locus_tag="L1V38_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1315430.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="L1V38_000866"
     CDS             complement(10618..11028)
                     /locus_tag="L1V38_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1315431.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="L1V38_000867"
     CDS             complement(11208..11642)
                     /locus_tag="L1V38_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1315432.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="L1V38_000868"
     CDS             complement(11742..12590)
                     /locus_tag="L1V38_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1315433.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            12979..14745
                     /locus_tag="L1V38_000869"
     CDS             12979..14745
                     /locus_tag="L1V38_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBN1315434.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            14847..16106
                     /locus_tag="L1V38_000870"
     CDS             14847..16106
                     /locus_tag="L1V38_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1315435.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            16253..17554
                     /locus_tag="L1V38_000871"
     CDS             16253..17554
                     /locus_tag="L1V38_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315436.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            17557..18408
                     /locus_tag="L1V38_000872"
     CDS             17557..18408
                     /locus_tag="L1V38_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315437.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            18421..19236
                     /locus_tag="L1V38_000873"
     CDS             18421..19236
                     /locus_tag="L1V38_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBN1315438.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            19387..20553
                     /locus_tag="L1V38_000874"
     CDS             19387..20553
                     /locus_tag="L1V38_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1315439.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            20783..21430
                     /locus_tag="L1V38_000875"
     CDS             20783..21430
                     /locus_tag="L1V38_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1315440.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            21514..22458
                     /locus_tag="L1V38_000876"
     CDS             21514..22458
                     /locus_tag="L1V38_000876"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBN1315441.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            22593..24044
                     /locus_tag="L1V38_000877"
     CDS             22593..24044
                     /locus_tag="L1V38_000877"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBN1315442.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            24065..24901
                     /locus_tag="L1V38_000878"
     CDS             24065..24901
                     /locus_tag="L1V38_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1315443.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            24901..25560
                     /locus_tag="L1V38_000879"
     CDS             24901..25560
                     /locus_tag="L1V38_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1315444.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            25686..26375
                     /locus_tag="L1V38_000880"
     CDS             25686..26375
                     /locus_tag="L1V38_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315445.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            26381..27337
                     /locus_tag="L1V38_000881"
     CDS             26381..27337
                     /locus_tag="L1V38_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBN1315446.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            27381..27893
                     /locus_tag="L1V38_000882"
     CDS             27381..27893
                     /locus_tag="L1V38_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315447.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(28149..28697)
                     /locus_tag="L1V38_000883"
     CDS             complement(28149..28697)
                     /locus_tag="L1V38_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1315448.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(28786..29967)
                     /locus_tag="L1V38_000884"
     CDS             complement(28786..29967)
                     /locus_tag="L1V38_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBN1315449.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(30203..31711)
                     /locus_tag="L1V38_000885"
     CDS             complement(30203..31711)
                     /locus_tag="L1V38_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBN1315450.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            31870..32061
                     /locus_tag="L1V38_000886"
     CDS             31870..32061
                     /locus_tag="L1V38_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315451.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            32264..33181
                     /locus_tag="L1V38_000887"
     CDS             32264..33181
                     /locus_tag="L1V38_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBN1315452.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            33174..34247
                     /locus_tag="L1V38_000888"
     CDS             33174..34247
                     /locus_tag="L1V38_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315453.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            34395..34913
                     /locus_tag="L1V38_000889"
     CDS             34395..34913
                     /locus_tag="L1V38_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315454.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            34894..35287
                     /locus_tag="L1V38_000890"
                     /pseudo
     CDS             34894..35287
                     /locus_tag="L1V38_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
     gene            35363..36298
                     /locus_tag="L1V38_000891"
     CDS             35363..36298
                     /locus_tag="L1V38_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBN1315455.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            36431..37210
                     /locus_tag="L1V38_000892"
     CDS             36431..37210
                     /locus_tag="L1V38_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1315456.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            37203..37520
                     /locus_tag="L1V38_000893"
     CDS             37203..37520
                     /locus_tag="L1V38_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1315457.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            37764..39374
                     /locus_tag="L1V38_000894"
     CDS             37764..39374
                     /locus_tag="L1V38_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1315458.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASGNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            39531..40379
                     /locus_tag="L1V38_000895"
     CDS             39531..40379
                     /locus_tag="L1V38_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1315459.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            40610..41089
                     /locus_tag="L1V38_000896"
     CDS             40610..41089
                     /locus_tag="L1V38_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315460.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            41122..43350
                     /locus_tag="L1V38_000897"
     CDS             41122..43350
                     /locus_tag="L1V38_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1315461.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            43479..45122
                     /locus_tag="L1V38_000898"
     CDS             43479..45122
                     /locus_tag="L1V38_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1315462.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45195..45740)
                     /locus_tag="L1V38_000899"
     CDS             complement(45195..45740)
                     /locus_tag="L1V38_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBN1315463.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(45763..46248)
                     /locus_tag="L1V38_000900"
     CDS             complement(45763..46248)
                     /locus_tag="L1V38_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1315464.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(46238..47050)
                     /locus_tag="L1V38_000901"
     CDS             complement(46238..47050)
                     /locus_tag="L1V38_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBN1315465.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(47189..>48300)
                     /locus_tag="L1V38_000902"
     CDS             complement(47189..>48300)
                     /locus_tag="L1V38_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1315466.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        15898 a         8765 c         9362 g        14275 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaattca ttaataatac tcttatctta ttataactta cttttcacct taagttaact
    12661 ttaattaata aaaaaattag gctagtctaa attattatgt ttcattcttc tagaatatac
    12721 ttctacgcca aaaactgtta aaaaactttt actttagaaa attggagaaa ttgatcgctt
    12781 aagataaatt caggacacta aatagtacag gaagtagact aaaactttta aaagttttaa
    12841 gtctatctat ttggcaagtt taaaaaataa aaattcggta tcaaaaaact gttaccgata
    12901 acatttttga aagcgttgtc ttttgcttct ctatcactta tagtgatgac gtcatattaa
    12961 aacacaagga ggaaatcaat ggatacagct gcaatttatc atcgacctga aagtgaatat
    13021 gcatttctat atacgaatac aagatttcgt attcggcttc gtactaggaa aaatgatatc
    13081 aaaaaagtat atgtgctatg tggagatcca tataccataa caactgaaaa atggtatcaa
    13141 aaacaacgac caatgaaaaa atgtctaagt accaatgttc atgattattg ggaaattgaa
    13201 gtgacgagcg aaacaagtcg cttacagtat gcgttccatg ttgttgggga agataacacg
    13261 gactgttttt acggtgatca aggaattttt ccttatcgag aaaatgtgat tactgaacca
    13321 aatttttatt ttcgaatacc ttattttcat caaatcgatc gattcactat tccagaatgg
    13381 gtaaaagaaa cagtatggta tcaaattttt cccgaaagat ttgcaaacgg ggacaaagca
    13441 aatgaccccg aacacacttt accttgggga agtaaagatc cagaccgaga agactttttc
    13501 gggggagatt tgcaaggtgt gatggatcat ttggattact tgacggacct tggcatcaat
    13561 ggcatctatt tttgtcccat atttaaagcc acatccaatc ataaatacga tacgattgat
    13621 tattatgagg tggatcccgc ttttggcgat aaaaaacttt taaaaaactt gattgatgaa
    13681 gcacataaaa gagggatacg tatcatgttc gatgctgtat tcaatcatat gggtgtccat
    13741 tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat cgatctataa agactggttc
    13801 cacatccgtt ttttcccagt agattcttat cagatgactg acttaccaga aactgctgaa
    13861 aatatcccat atgatacttt tgcttttact ccattcatgc cgaaactaaa tacagcaaat
    13921 ccagaagtgc aaaaatattt gctggatatc gcaacttatt ggataaaaga attcgatatt
    13981 gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc atttttggaa aaaattcaga
    14041 gaagcagtta cagaaatcaa accagacatc tatatccttg gagagatttg gcattcctct
    14101 caagcttggc tgcaagggga tgaattccat gcagtgatga attatgcatt tacagattcg
    14161 attaaagatt attttgcaaa aaagaaaatc acagcttcac aaatggtcag tggaatgaat
    14221 catcagcaaa tgctttacag agatcaggtg aacgaaggaa cattcaactt attagattct
    14281 catgatactg ccaggatctt gaccctttgc caaggtaaca aagaattgat gaagtctgtg
    14341 atggccttta tgtttcttca aaaagggtct ccttgtatct attacgggac agaaataggg
    14401 atgactggtg aagatgaccc ggattgccgc aaatgtatga tatgggagaa ggaggaacaa
    14461 gatctagagc tattcggttt tataaaagaa cttgtttctc taaggaaaca gttgtctaag
    14521 attatttctg aaggttctac tcagtggcta atagtaaatg atcgtgaaga taagctctat
    14581 ttcacacgga aactagaggg acagatcatc tatgtttact ttaatcagtc aaaagaacct
    14641 tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa attgtcagtt gttagaagac
    14701 gggaaagcag agatacgaca atacggattt ttgatcatgt gttgaaaact gttaccggta
    14761 acaacaagaa agcgtttgca aatgaagatt tgtgcccatt ataataaggg tgtaacagca
    14821 cgttgaatac aaaggaggaa atgaagatga aaaaaagaag tgtgaaacag ttgggtttag
    14881 ggttaatctc tttaggaatc ttaggcggat tagcggcttg tggcaatggt aactcttcag
    14941 cagaagggga agccgatgaa ggaaaaacgt taacagtttc cgttgattct ggatataaag
    15001 attatataaa cgaaataaaa aacactttcg aaaaagaaaa cgatgtgaaa atcaagctag
    15061 tagaaaagga catgttcgat cagttggaat cattagcgtt agatgggcct gctggaaagg
    15121 gacctgacgt tatgatggca gcatatgacc ggatcggtgc gttaggacag caaggacatc
    15181 tggcggaagt aaaactggga aatgaagcag cttacgatga aacagacaaa gcccaagtga
    15241 cttatgatgg aaaaatctac ggagaacctg cagtaatcga gacccttgtt ttgtactata
    15301 acaaagattt agtcgataca gcaccatcaa cgtttaaaga tttggagaat ctatccaaag
    15361 acagtcgttt tgcttttgag tcagaagcag gaaaaaatac aggattttta gctaaatgga
    15421 ctgactttta ttattcctat ggtttaattg caggttacgg tggctatgta tttggtgatg
    15481 atggcacaaa tccttcagat atcggtttga ataatgcagg tgctgtagaa ggaatctctt
    15541 atgcaacaga ttggttcaaa aatgtttggc caaagggaat gcaagacata aaaagtgcag
    15601 gagacttcgc cagccagcaa ttcatgtcca ataaaactgc agcaatcatt gacggtccat
    15661 ggcaagcgca aacatacaaa gaaaacaata tcaattatgg tgtagccaaa attcctactc
    15721 taaataatgg acagccttat caaccgtttg gcggaggaaa aggatgggta gtcagcaatt
    15781 atgctaaaaa caaagacctc tctcaaaaat ggcttgatta tgtaacgaat caggaaaatc
    15841 aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa ccaacaagct agggaaacag
    15901 caaaggctaa aaacgatgaa ttaacaacag ctgtgattga acaatatgaa acagctcaag
    15961 cgatgccaaa catcccagaa atgggcgaag tttggacagg tgcagaaaac ttgatgttcg
    16021 atgcagcatc aggttcaaaa acaccaaaag aatccgcaga tgaagcagta aaaacaatca
    16081 gtgaagccat agaacaaaaa tactgattaa aatgataacc gtccattttt ataaaaaatg
    16141 gaacaggtgc ttcagataaa agtggcaaga gcgagatgga aaattatctt gctcttgttg
    16201 ccattatctt aaaagcagtt tgcggtttag caagtttaga gggggcattc agatgcagca
    16261 agataaaaca agcaatatca acgaaaaaaa aatcacgctt tgttcactta ttccagggat
    16321 ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt tttttcgcca tattcgtcct
    16381 attcattggt cagatgcttc tgggcggatt tcatgcattg gtaggattgg ttactttggg
    16441 aagtatacca atggaagatc attcattatt tattttgatt gaaggcactt tgcaattcat
    16501 cattacaatc attttcttga ttttttacgg tttgaatctt ttagacgctt atcgagtagc
    16561 gaagatgcgt caagagggca aaaaaatcaa tcggacgatg aaggaagtca tacataatat
    16621 aggtgatgaa ggttttcctt atctattgac acttcccgct tatcttctca tgatttttac
    16681 gatcattttc ccagtcctag ttacattgtt cactgcattt actaattatg acttcaatca
    16741 tattccacca gccagtttaa ttgattgggt aggggctaaa aactttttta gtatcttctt
    16801 tttaagctca tatcgtaata ctttttttgc agtcttttcg tggaccgtga tttggacttt
    16861 atgtgcaaca actttgcaaa tcacccttgg tattctcaca gcggttgttg ctcaccagaa
    16921 atttattaaa ttcaaacgta ttttcggtat cattttctta ttaccatggg cggtcccagc
    16981 ttttattact atcatgagtt tttcgaatat attcaacgat agcgtaggtg ccatcaatac
    17041 tcaagtgatt cctttcataa accagcttcc ttttgtagat atcagtgcaa tctcttggaa
    17101 aacggacccg aactggacga aagtagcaat tatcttagtg cagggctggt taggatttcc
    17161 ctatatctat gtgatggtta caggaatctt acaatcgatt tcagaagact tatatgaagc
    17221 agcaaaaatc gacggagcaa atgcatggca gcgcttttca aacatcacgc ttcctgctgt
    17281 cttcctagtg gcagcgccaa catttattac acagtatacg gggaatttca ataatttctc
    17341 catgatctat ctgtttaaca atggcggtcc cggaagcgta ggcggaggag ctggttctac
    17401 tgatattctt atttcctgga tctataaact tacgactgga acttctccgc agtattctat
    17461 ggcttcagca atcacgttga ttatctccgt catcgttatc tgtgtgtcat tgctggtatt
    17521 taaaaagaca aatgcgttca atatggggga ttaacaatga aaaaatttca ttcgagtgct
    17581 cgattccaaa aacgactttc tcactttttt acttactttt ttcttttaat actgtcagtc
    17641 attatcatct atccgctttt gatcacagca agtactgcct tcaagtcagg aaatattgca
    17701 gcttttagtt tagatctttc aagtgactgg actttaggaa actttactcg gctattcagt
    17761 gaaacacttt acgggacttg gtataaaaat acattgatca tttctgtcct aacaatgatc
    17821 gtacaagtga ctgtagtaac tttggcgggc tatacttata gtcgctatcg ttttatcggc
    17881 cgcaaatcaa gtctgatgtt ctttttagtg attcagatgg taccgactat ggcagcattg
    17941 actgcctttt atgtcatggc tttcttatta gaagcgctcg ataagtactg gttcttgaca
    18001 atgatctata taggcggtgg aattccaatg aatacttggc tgatgaaagg atactttgac
    18061 actgtaccaa tagatttaga tgaatctgct aaacttgatg gggcagggca tttcaggatt
    18121 tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg ccgttcaagc attatgggct
    18181 tttatgggac cttttgggga tttcatgtta gctaagttcc tgcttcgaac acctgaaaat
    18241 cagactgttg ctgtcggctt acaaacattt atttctgatg tgacaaacca aagagtctct
    18301 ctttttgctg ctggggcaat tttgattgca ctaccgattt gtctattatt cttcttttta
    18361 caaaagaact ttgttaccgg cctgacatct ggcggaacaa aaggatagga gcagagtatc
    18421 atgcaaacat ttccgttaaa ctatttttcc gcattacgta cgccaactca agtgtttgcg
    18481 ggacgcaaac tattatcatg gcctaaattt ttcttgatat ttgtattttt agtttccttg
    18541 atggtcatgc ctgtgactct tttttatgcc aatcagatcc aagcgattcc attagaacaa
    18601 tttctatccg ttcattcgct gatcgatgaa caaggaaccc aaaaattttc tgaacttgaa
    18661 ttatctgaaa ctgggttaca agcatcgcaa caaacgatag ctgtgacccc tgaaattttg
    18721 gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat tgattttgag
    18781 aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta tacgatgaat
    18841 tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca acgattttta
    18901 gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag tttaagtctt
    18961 ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt tttcttgtgg
    19021 atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc aaatttgatg
    19081 ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat ccactttgac
    19141 tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt atgggttttt
    19201 gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat ttatgcgaca
    19261 atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa aaaattaaac
    19321 ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt tttaaggagg
    19381 aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt ctcgctccct
    19441 gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga cactcctccc
    19501 caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag taacgcatct
    19561 ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag tatccaagca
    19621 ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga ttatctaaaa
    19681 tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat ccatgcgcat
    19741 tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac ttattcttgt
    19801 gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa agtccatcat
    19861 atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg ttgtggctgg
    19921 ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg gatcacacta
    19981 agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt agaagataaa
    20041 tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga tcatatcaca
    20101 agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt caaagtggta
    20161 aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg acaacaaggc
    20221 ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt ccctggtgtt
    20281 actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt ggaaagctta
    20341 cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca agtccaagat
    20401 caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata tttacaagct
    20461 tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct tgttcaacct
    20521 ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg tttaaagact
    20581 atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt ctaacttcta
    20641 ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa gtttggttct
    20701 ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag aatactattt
    20761 tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt tatttgcagc
    20821 tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga atacgtcttc
    20881 cagtagcgaa cagcgctctt cacaggtatc ggactcctca acaaaagcaa gcacatcttc
    20941 gtctagccag acaaaaagtt ctagtgaagc aagtactcag tcagatatca aagtgtctgc
    21001 agctcgtgcg atcgaattgt tccaagataa atacccagat actgcaatta ctagtttgga
    21061 attagatagt gattggggat cttacttcta caagatagaa ggtgtcgatg atcaaaaaga
    21121 atacgaagca agaattgatg ctcaaaatga aaaaatggag acagagaatc cagaaactct
    21181 agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat ggtctggatg ttgataaatt
    21241 gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa gtaggaagcg gtacggcaac
    21301 agattgggat ttggataaag atttaggtac tacttattgg gaagtcaaag taaaagacgg
    21361 caatcaaagt acatcagtca agatcaatag ccaaacaggc gaagtactgt caactgaaca
    21421 agatgattaa gaatttcttc ggaaaacaag agttgatttt tcttttagtc atgatacact
    21481 agacaaaata acttgtttga aggagcgatt tacttgagtt tagaaacgac ctttgccaat
    21541 catatctttg ccaatccttt gatgaatgca tctggtgtcc actgcatgac tacccaggaa
    21601 ttagatgaac tggctcattc agaagcagga gcatttatca ctaagagctg tacgatcaat
    21661 gaacgaaaag gaaatcccga accacgctat tttgatgttc ctttagggag tatcaattct
    21721 atgggacttc caaacttagg tttttcttat tatctagagt atgctcttgc gtatgaaaaa
    21781 gtgcaggaaa accaaaatca accgttattt ttttccattg ccgggatgag tgtccaggaa
    21841 aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac tgaattaaat
    21901 ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga ggccacttat
    21961 gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa attgcctcct
    22021 tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt tccattgacc
    22081 tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga acaagaagca
    22141 gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat caagccgact
    22201 gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca aatcattggt
    22261 acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg cgcaagcatg
    22321 ttacagattg gtaccgagct tcataaagaa gggccggaaa ttttttctag aatcataaaa
    22381 gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa
    22441 ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc tttttttata
    22501 aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt
    22561 gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa ttagcaaaag
    22621 agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag aaaaaaataa
    22681 agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag agtaattccc
    22741 acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca tttcctttaa
    22801 aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt ttatttgaaa
    22861 cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata ggtctagttc
    22921 cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac ccagtcatct
    22981 atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca agtggaggag
    23041 ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt
    23101 ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg cgagggacga
    23161 tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat ttcggcttga
    23221 cagtttctat gagagacacg gaggctttat tttatgggat gagaagtatc cattccggtg
    23281 cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga
    23341 tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca gtacttgctg
    23401 taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag attccttacc
    23461 cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca gaaacagcag
    23521 caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa gaacttgaac
    23581 ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact tacatcgatt
    23641 ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa gaatacgatc
    23701 tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg
    23761 atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa ggtttagacg
    23821 ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag ttggctaatc
    23881 tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac atgcctctag
    23941 gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc ggctatctat
    24001 ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa caaggagaag
    24061 aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta ttttaagcgc
    24121 ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag aaaaaaagaa
    24181 agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata atgatcaaaa
    24241 tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt taaatgtcaa
    24301 aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa aaagagaatc
    24361 agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc
    24421 agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg attcaggaat
    24481 ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata ctagctatat
    24541 gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca cgaatgatca
    24601 gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt attatctgca
    24661 gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga acgtttattt
    24721 caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga aaaagaaaat
    24781 cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata
    24841 ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg
    24901 atgtactttc ctctaattga tttttccctc atgtggactt cacttccttt cgtactgcaa
    24961 ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa tctggtaggg
    25021 ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt tattcgtttt
    25081 tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt atattttggg
    25141 ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat taccagcagt
    25201 gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg tcagtgggac
    25261 gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt tttgccgcaa
    25321 gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt gaaaggtact
    25381 tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat cataggcggt
    25441 cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg ggtcatttgt
    25501 atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatgcatca gtcaatctga
    25561 aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc ttgtatattc
    25621 tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag
    25681 aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa tattgcatcg
    25741 agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga attgtagata
    25801 cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat gagctgaaag
    25861 tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat tataattatt
    25921 ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca ggaataggtg
    25981 ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt acatttctga
    26041 ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg acaaaccgct
    26101 tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat
    26161 attttccaac agatcaattg tacaaagaat tgaaaagacg ttcagaaaat caagatccat
    26221 tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag gcaatcaatg
    26281 agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg caacaacagc
    26341 agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc cttatttaag
    26401 aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat tgctctccaa
    26461 taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa atgtgatcga
    26521 attatttcaa aaaaagcacc atcgaatcgc tgtgatccaa aatccccaag taggacaatt
    26581 caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc
    26641 tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc cagcgtttct
    26701 tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt tggcaggagt
    26761 tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc ccgaaaacaa
    26821 aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg cagataaaac
    26881 agatgacttt tttagtgatg actatctttt tttccacgca gacggatata ttggattttc
    26941 tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc gagcgcttgc
    27001 tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt ttgtctctga
    27061 cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag ataaaatgaa
    27121 aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga ttgaattatt
    27181 ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt ggtcacttat
    27241 gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc ttaaatatta
    27301 ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa atgaaaaagg
    27361 aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa gtagaagaag
    27421 tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct cctcaatggc
    27481 aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga aaagaaagct
    27541 atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca agcgtggatc
    27601 ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat ttatcgattc
    27661 atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg ttcttagaac
    27721 atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat acttatccag
    27781 ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa gggatgattg
    27841 aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat tgactataaa
    27901 atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat atgatagcca
    27961 agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc
    28021 tcaaattttt gtggaatttt agcgtatttt acgaaatagc tgctttctga aactcccttc
    28081 atcgagaggt cgtgacatag cttttgtcac gacctctcgg cttatcctac gagtattatt
    28141 cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg gaacgctcca
    28201 tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg tgctaaatct
    28261 tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg ttttttcagg
    28321 cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac cgtcccgaaa
    28381 tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt tcctactgtc
    28441 agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata ttggtcccac
    28501 tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac aaaataataa
    28561 tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat gatcttttgt
    28621 tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg accgataaat
    28681 acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa aaagctttgg
    28741 aaaatatttc caaagctttt aaaagtaact ttgctttttt gtatattata ccagcaagcc
    28801 agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt tcaatccgtg
    28861 ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag aaatgatccc
    28921 gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg ttgtacgctc
    28981 agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat ttgtaaccag
    29041 tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc cgctgatgaa
    29101 ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga atatcccgtg
    29161 gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag cagcaaccgt
    29221 gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa atgtctgttc
    29281 tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg gatttacaat
    29341 tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca catatttaga
    29401 atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca tagccgatac
    29461 actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta tggaaataaa
    29521 aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca atttgcccat
    29581 cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa gaatcttgat
    29641 atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata cggaaagaaa
    29701 gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc
    29761 aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg taccaaaagt
    29821 tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa ttagtggttt
    29881 caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg tgacaaataa
    29941 accaataata cctaataaat aactcaaata atcactccta ttccaaattc cgttttattt
    30001 tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt ttttagagtg
    30061 aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta
    30121 acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag tttcgttttc
    30181 aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg tagacaggtg
    30241 cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta ttgaccatca
    30301 cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca acttgagcga
    30361 ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg cttagtgcat
    30421 ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga actaatggtg
    30481 acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt aagataactg
    30541 ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca tctggtaatt
    30601 cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc ttatctgcat
    30661 agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact tcttccataa
    30721 tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg
    30781 tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg gtatcatcca
    30841 cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa acagattctt
    30901 taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca tcccgattat
    30961 agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata ttgacatctt
    31021 ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac ggaacattcc
    31081 atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg ctttcatgat
    31141 acagttggtt caaggaagta gcgagctttc cacttcctgg gccaggagct gtcactacaa
    31201 cgattggttt agttgtttca atatactcat tttttccaaa accatcttct gagacgattt
    31261 tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg atgtttcgtc
    31321 tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga gtgataacga
    31381 cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag atatccatat
    31441 cataagtaat cccataatca ccacggatct tattacgttc aatatctcca gcatagacgc
    31501 aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc gcatcttctt
    31561 caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac tagcttccca ccaaattcta
    31621 aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc tcttcaatat
    31681 atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta ctaaagcatt
    31741 ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa
    31801 aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt ttgataagga
    31861 aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta tatccgttcg
    31921 atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt gacgtttact
    31981 tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca tttcacaaca
    32041 agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat tctgtcctat
    32101 cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt
    32161 tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt actattgaag
    32221 tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag agccagatac
    32281 aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg atacaggaca
    32341 agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt cccaattatt
    32401 agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg agatctaccg
    32461 tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat
    32521 cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc cttttatgga
    32581 acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt attaccatga
    32641 tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc ctaagatcga
    32701 tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa aaatcaatga
    32761 gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg aacaaataaa
    32821 agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa
    32881 aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta atgaaaaatt
    32941 aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag aagcattgaa
    33001 gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat
    33061 cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat tcttgatgaa
    33121 ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg agtatgaatg
    33181 aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat gaagaaacga
    33241 acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa atccctatgc
    33301 tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg aatactgcag
    33361 aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga aaagagcaag
    33421 atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg gatttacgta
    33481 tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat gatcgtttta
    33541 tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa tacttcacgt
    33601 atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca gcttatgaca
    33661 catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac gaattagtct
    33721 tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg agtctcctaa
    33781 acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt tctttgatcc
    33841 gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc aatcacaaat
    33901 tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag acattactag
    33961 acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg aatgaagtat
    34021 tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa aagatcaacg
    34081 aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca acaaacgaaa
    34141 aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc attgatttct
    34201 ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg gataagttgg
    34261 attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt atccagaata
    34321 attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct gatgaaggag
    34381 ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg tctgctgctt
    34441 gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg actgctattt
    34501 ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg agtctttcta
    34561 ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa tggatcagct
    34621 atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc
    34681 tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata ggtatgaccg
    34741 tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt caaggggtgt
    34801 cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg
    34861 tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta tagtttgctt
    34921 gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac acaatcggct
    34981 tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat
    35041 ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag gcgatgattt actgagtatt
    35101 ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct tgaagggcac
    35161 tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa aagtgctact
    35221 actggtgcca aagagatcaa aatgtaatga tggacaatcg gtcattttca atttgtctaa
    35281 actataagtt tcataaaaaa ctgttaaagg gcgaatattg ccataattca gtgagttcag
    35341 ttgatgaaag aaggaaaata acatggaaaa ttttaaaaaa agcggaatgt tttccgtaat
    35401 tgctgctcta ggggctaata ttctagttgc tatcagcaaa tttgtcggct atgcaatcag
    35461 tggcagtgcc gccatgctaa acgaaagcat ccacagtatc gttgattgca gcaatcagat
    35521 tttgctgtta ttcggtgata aacaagccaa taaaggacag agcgagttgc atcaatttgg
    35581 tgaaggacga gcaaaatact ttttcagtac aatcgtcgca atgatgcttt tcttcggcgg
    35641 tggggcactt ggggtgatgg aagcttttga aaagttgacg catccatccc atgaagtggg
    35701 taatccgatc attgttatag caatactgtt atttggtttg gtaatcgaag gaagttcgtt
    35761 acgcgtggca atgaaagaaa tcaaagaatt gaatactgaa aaactttcca cgatgcgctt
    35821 tttgcgcgaa agtcgacaca gtgaaatact gattattttt acggaagact tgtgtgctgt
    35881 aatcggtttg gtcttggctt tagcaggaac aatattgact tatgcaaccg ggattgctgc
    35941 atttgatgcg atcagcggat tgctgatcgg tttcttgctg atgggagccg ccattttcct
    36001 agcaaaagaa ttttatagtc tgatcatcgg tgaaagcgtg acagcaagcg atttatcaaa
    36061 aatcaagtta gcttttgaac gtcctgagat cagtcggctg atcgatataa aaacagttca
    36121 tttaagtcca acggagattt tagttgcagc aaaagcagat atcgttggta acaaagagaa
    36181 tgaagcttac tcggtcatca atgatattga aaaaaatatg cgtcagtctc ttcctgacaa
    36241 gaagatgtat atatacattg aaacagataa atatgaccca aattattctc gtaaataaaa
    36301 cgtttattca tgaattgaag caaaaatgag aaaaatataa tcttgttttt aaataaaacg
    36361 gctacaattt agcgaattta tgttacaatg agtccgctgt ttatttgttg taattaaagg
    36421 agatatttta atgaacaaaa agaaaagtgc gccatggctt caagctttgc atgcagtgat
    36481 gccactttgt ataagctata taccagtagg attagcttgc ggagtattgt tgcaaaaagt
    36541 tggatttgat cctctcttat caggactgtt atcgattctg gtcttttccg gtggcgcgca
    36601 gtttttagtt gcatctatgc ttacgacgca agcatcattt gcaacgacat tattgatggt
    36661 tttcttttta gaattacgct atacattatt aggagcaagt cttgccggtt ttatgaaaaa
    36721 agaaaagcgg acgtttttgg ctgtcttttc tcaatcactg aatgatgaaa actatgcggt
    36781 gaactactta aagttttcaa ctgacccttc ctggaataaa agaaaggctt tatatgtcaa
    36841 ttggttctca atgactgcat gggccggtag caatatgatc ggtaattttt tcggctcggt
    36901 gattcgagta gatgctgacc ttgtccattt tgctttgacg gccatgttca ttttcatgtt
    36961 tatcatgcag atgaaaagcg cactactgat ctttacaggt ttattctcag gcgtattagg
    37021 ggtcgtattc atggtattat tccaaaatac tttcggattg attgcagcaa cagtcattgc
    37081 ttcatttgcc ggatttatgc tggagaaggc attcaaaaaa gaaaaagcta agaaactaag
    37141 agaccgcggt aaagatgtca atgagccgct cttcaacttc ccggaacagg aggccaatca
    37201 ccatgactaa actatatttg ctacttttag ttgcttgtct gttcatcgtg gcatatatcc
    37261 cgcgcttgtt cccgatgctt tattttactc atcgaaaagt gccatcctgg ttcagtgact
    37321 ggatgaaata tgtaccggtg gcattatttg cggcgttagc ttttaaagat gttttcatta
    37381 ctcatgaaca tctggatatt gcttggaata tcaaaatagc tgcaatgatt ctagtagcag
    37441 gcgtggctta caaaacacgt tcgatggcgt tgtcagtttt gacaggactt gcgtctgtct
    37501 ttttgctgtc tatgctttaa actgttttat tttattaaaa acagagattg cgacataagt
    37561 tgttcaaact gatctatccg aactgcattt gcaacagtca attctggatg caagtttatt
    37621 cgtagggata aaaaagatta gtgttggctt atgatgcaag ctctttttta ttttaggaat
    37681 tagagaggga tttgtccttc tatgattttt tgctataata gggaagatgt ttattttatg
    37741 aaagaatagt tgagggaatt taaatgaata aaaaattgat gcaaggaaca ttttggctaa
    37801 cctttgctaa tcttctatgt aaagttttag gggtagtcta tttgattccc tggctaagta
    37861 tgatggggaa caatcaagat ggtatgcttg ctacgacatt gtataatgtt ggctatcttc
    37921 cttatggatt gttcctgatg cttggtacag tcggatttcc aaatgcgatt gcaaaaaaag
    37981 tagctgtagc cacaaaagaa ggagataacg ctgcttgtcg gctgattttt agaagtacga
    38041 tcaatatcat gtttgtcatc ggtatcgcct ctgctgcact gatgtattta tttgctcctt
    38101 tactagccgg aatcagtccg attgctaacg ttaataatgg gatactagct atcagaagtt
    38161 tatgcccatc tttgattgct atcccaattc ttagtgcaat gagaggatat ttccaaggaa
    38221 aaaatgatct gcggccttat ggaacttctt tgattatcga acaggctgtg cgagtgatcg
    38281 ttatcttggc tggtacttat tacttgcgcg tattgactga cggaaccata ttagaagctg
    38341 tattgatcag tacagtcgct tctttcttcg gtgggttagc tgcgattatc catatgtata
    38401 tcgtcggacg cagaaaagac ttcttcgaac ttaaagattt tttgatttcc agccgttatt
    38461 tcgaaagaga aaaccgatct gcctctgtct ctatcattcg ggaaacacta ccgtttattt
    38521 ttgtcggctc agtcattact atcgttcaaa tgatcgacca agtaacgatg aaaccactgc
    38581 ttcacttttt ccgtccagag atcgcagatc agcaactgga attcttattc agccgtgctt
    38641 ctggcaatcc aaataaattg acattgatcc tgatctccat ggtaggaaca gtagctataa
    38701 gcagcttgcc aatattaagc acgatgaaga aaaaagatcg gatacaaatc gaaaaaacag
    38761 taggagatag tttttcgatt gcgttattga ttcttcttcc ttcattgact ggaatgtctt
    38821 tattagctgg accactatac acattgtttt ttggctatga tcctgaaagt gtcggatatt
    38881 tccaaatggc tttgctagct tctttgtttt tctctttatt cacgatccta tctacgatgc
    38941 ttcaatcttt gaatcaccat cgttttgcga tccgattaac tgtagaagca attatcctga
    39001 aagtcatctt ccaagtaatc ggattaggat tagttggcgg atacgggatg agcttatcaa
    39061 atggcttagc attcggtatt gtctttgttc gcggctatca ctttatgtgc aaagaatacc
    39121 gaatagcacc tttagcaaag atcagcaatt ttttcttaaa aactttccgc tccaccctga
    39181 ttatgcttgc agtatgtttt gccgttttct ttttgctgaa tcagcgattg tcaatggaat
    39241 caaaaagcta tgcaatgatt tattgtgtgg ctgtaggaag tattggcggc ttagtatttt
    39301 tattttctca attcggaaaa aatgggtttc gaatgttgaa aaatgttaaa catcatagca
    39361 gaagcaaaga ataggttaac taatcgtttt ttgctgtcac ttgaaaaacg gcaactcgta
    39421 tgattacgct tgtcgttttt ctattttcca attttagttt catatctaat cttacttatg
    39481 atatagttat aaggtctgga aaaattcttt gaaacgagga aattaaacac atgaaacttg
    39541 cagtagttac agatagttcg gcatatctgc cggaacgtat caagaaccat cccgacttat
    39601 tcgttattcc aatccctttg attatggatg ggaaaattta taacgaagga atcgatatcg
    39661 aagcggatga atattatgga cttttaaaaa acagtaaaga ttttcctact acttcacaac
    39721 ctgtcgtagg ggaagttttg ggtttatatg aggaattgaa agagaaaggg tatgacacga
    39781 ttttaagtat ccatctttct tcagggattt ctggctttgt caacacatta tttgcgatga
    39841 aagatgacat cagcggagta acggtcattc cttatgactc taagatcact agtatgccga
    39901 tgggacacat ggtagaagct gccttagact taaatgatga aggtcagtcc cttgatgaaa
    39961 tacttgcaca tatcgatcga atccgagata atacctacgc ttatctgatt gtagatgatt
    40021 tgaacaattt agtacgagga ggacgtttga caaatggtgc agcgctgatt ggcagcttat
    40081 taaaaatcaa accgatcctg acattttctg aagggaaaat tgttttattc gaaaaaatcc
    40141 gttcaagtaa aaaagcattt gctcgagctg aagaaattat tggtagaaga aataacgaaa
    40201 tacaaccgcc agtcaaactt tacgtgatac atgcaaataa tttagaagta gcgattgcgg
    40261 agaaagagaa attgcagaaa aaatatccaa atgcagaaat cgaaattggt catttcggac
    40321 cagtcattgg tacacattta ggtgaaaaag ccatcggcat tgccatttca gcgcaataat
    40381 tccttttatt caaaaaacat accaaaaata ttccaacatc atcttggact ttctacatgt
    40441 tactaatgag cgtgtaaaag aacgagatgg tgtttttatt tctatcaatg aagctctttt
    40501 tctttgcaat cctcacttca atcctctata atgtcgcata tagtttagta aatgagtaaa
    40561 ctactaattt acttatttac taaaaataaa aggatgagga gttaaaataa tggaaatacc
    40621 aacaaattta aaacataaac cagtaatcgt tgtagaagac tatgataaag ttgatggaag
    40681 aaatgcatta aatacggatg caaaagggct ttcactgggc cttgctcagt ggaatgatcg
    40741 tggaaaagtc gatatctcag gcaaggtatg gcgacatact ggagaaaaat ggtcacgaca
    40801 gtcggaagaa ttaccaatca cacgtatttt agatttagcg atcttagctg cacaaggaag
    40861 tttatacttc caagatgctt atcgttatga aaaattttat gatccagaaa atccagtcgt
    40921 agacatcatt ggattacaag ggaaccgaat gacggtagaa gtagatacca aaaatccaaa
    40981 gatcgatgaa gacatcattt tgtattacga tacactacaa aaagacggag aactgattgg
    41041 ggaacgattc cgtattttaa aacgtctttt agatgagcta ggatattaat agacagagat
    41101 gatcaaaagg ggaagagaag catggagaat ttctcactaa cagaaaaccg aaccttttca
    41161 cggctagaaa agcaaatgat ctggaagaaa ccgaaaagcc atcggacaag tgcagaagaa
    41221 tggcggatcg cctccgaaat caaagggaat tggcaagatc ctgaaatgaa aatcagtaac
    41281 gtacttttgg aaggagatgc cgggtcgggg aagacacaat tagccaaagc actatctgct
    41341 gatctgcaac ttccctatac aaaagtgacc tgttttgcag atatggacaa atcagatgtt
    41401 ttcggagcct tattacctgt agtagattct aataaggaac aagaccaaga attactagaa
    41461 gctatttacc aaacagatac acttgaagct gtactgacac tgatccagaa ccattacggc
    41521 attgatcctt tttctgctaa agaaaaatta gcagagctag ttcaaaggat cgaagctgat
    41581 tatccagatg caatccatta cagctattac ccttctgaaa tcgttcgagc gattgaaaaa
    41641 ggatatttat tagagattca agagccgact gtcatccgag atgcctctgt tcttgtggca
    41701 cttaactcag cgctcgaacc aaatgggatg ttgaatttac cgacaggaat cattcgtcgc
    41761 catccagatt gcgtcattgt gatcactaca aatcgaaatt accaaggaaa tcgcccatta
    41821 aatgaatctt taagagatcg gatgcaacat gcggaaaaaa tggatcttcc tgccttagaa
    41881 gtcatggcag aacgtgcgat ggcgaaaact atgatccaaa aacaagaact tctcttaaag
    41941 atggcagaga ttatccgttt gttggatgaa actgcaaaag ctaacgccat caaaggtgta
    42001 gcaggaatgc gttcttattt ttattgggca aatacctata agcaaggaca agatttactc
    42061 cagtcgattt atccaaaagt tttgtataaa ttatccactg attcagatga attggcaatt
    42121 cttgaacaag ctttgtctga cagtggattg ctactggaac ttcaggacat attgagaaaa
    42181 gaaaaatggg gtcatcctca atctgagcat acaaaaggaa gaaccattag cgccgaagaa
    42241 gcaaatgaac gaaacatcac tgaaaatgct gaagaaattc tgcgcttaga tgaaaagaaa
    42301 tcgttgtctg ctgaagaacc aaatgaggga gaagagaaac aagaagaaac aatagaaaaa
    42361 aacgagattc ctcctcaaat gcaaaaagaa cgcagtagcg atatcgaagg aaaaaatcaa
    42421 aaagaacaac aaacaggaga tgattctcaa gaaatgtctg cttctgacat ggaagcacat
    42481 gataaggaaa tcaagaagca actgaataaa gaagcgcgac aaatcatgaa ggaaacgatt
    42541 catgaaaaag aaggtctcat cgttcaccga ccagctttcc aaggaaaaac gccggaagca
    42601 cgtgagctac acatgcaagt aatgccaata gtagaatcac ttagccggca aattttagag
    42661 ttactggata atgaacaaac agagacgtac caaaaaggaa aatacgaagg tcagcggttc
    42721 aatgcaagca aagtagcata tggtgatttg agaaattttg acaaaaagaa cccgccacat
    42781 gagcaacctt ctttagcggt agctgtacgg atcgatgaat ctgggtcaat gatacgggat
    42841 gatcggatcg aagcggcaaa aaaagcagcg attgccattg ccgaattttc taagaaagtc
    42901 gatatcccat tgttgattta cggagataca gcagaccgtt cgtcaagaga aaagacttct
    42961 ttgttttctt ataaagaatt tgaagacgga tttcaatggt taaatgaaaa attagtcact
    43021 atgaaaccaa ggcaaaacaa tcgtgatggt gctgcacttc gtttagcagc agaaaaatta
    43081 aacagacaat ccgcaacaac caaactgttg cttaatatta gtgacggtca gccaaaagcg
    43141 ttgccggatt atacaggcaa aaaagcaaaa gaagatatcc agtctgtttt gaaagaatat
    43201 gaacgtcaag gaatcctatt tgtctccgca gctattggcc aagacaaaga agaaatcaag
    43261 tcgatctacg gtgaaagtcg ttttgtagat attactgact tgaatgaatt tcccaagcaa
    43321 atgattcaac tgattgcccg ctatctatga taaaataaag ctcaacgaac gcacttagca
    43381 gattcgttga gcttttcgtt tctagttacc ggtaacaagg atacttctaa aatagaatcg
    43441 gttataatca agagggaccg ttaaaggagt gaaacgatat gatacaagaa caaaaatggt
    43501 ggaaagaagc agtaggctat caaatctatc ctgctagttt caaagatagc aatggcgatg
    43561 gtcaaggaga catcaatggg atccgtgaaa aacttaatta tttgaaagat cttggtatcg
    43621 gctttatctg gatcaatccg atctatcaat ctccatttgt cgataatggt tatgacgtaa
    43681 gtgactatca agatatagaa gagagattcg gaacgatgga agattttgat ttattgctaa
    43741 aagaagcaca tgaattaggg atcaaagtga ttatggatct tgtcatcaac catagttcgg
    43801 atcagcatca atggtttgaa gaatcgaaaa aatctaaaga aagcccgtat cgcgattatt
    43861 acatttgggt cgacggggta gatggcaaag aaccgaataa ttggacatcg attttcggcg
    43921 gttctgcttg ggagtattct catgaaactg gacagtatta tctgcatgtt tttgcaaaag
    43981 aacaaccaga cttaaattgg gaaagcgaga aattgaaaga agaactattc aatatgatcc
    44041 gatggtggtt ggataaaggg atagatggat ttcgtttaga tgcgatttct catgtaaaaa
    44101 aagatgaata ttcagtaaaa gccacagaga accctttctc accctttcaa aatgtctcag
    44161 gaatcgaaga acatttgacc gatttgaaac atgtttttga agagtacgat atcatgactg
    44221 tcggagaagc aagtggtgtc actgcagaag aaggaccaca atgggtaggg aaagacggtt
    44281 atttcgatat gatattcgaa tttgatcata tccatatctg gcagcaagaa aaagaagggc
    44341 aattagatgt ccttaaattg aaacttgcat taagcgcttg gcaaacttca ttggatggta
    44401 tcggatggaa cgctttatat atggaaaacc atgatgttcc tcgtgccgtt tcagtgtttg
    44461 gagatactcg tcccgatttt tgggctatgt ctgcaaaagc aatcgctatg atgtatttct
    44521 ttttgcaagg tacgccattt atttatcaag gacaggaaat cggaatgacg aatatgccct
    44581 ttgaatcgat cgatcaagtt gatgcagtag attcgaaaag actttataaa aggctgcttg
    44641 cggaaggtaa gacaagagaa gaagcattgg atatcattcg tgaaacaacg agagacaaca
    44701 gcaggacacc catgcaatgg acttcggaac aatatgctgg tttttctaca catgaacctt
    44761 ggctgatcac taatccaaat accaaaacga tcaatgtaga acaacaagaa tatgaaccag
    44821 agtcggtcct gcaattctat aagaacatga tccgcattag acaaaccaat aaaggtctga
    44881 tatacggttc ttataaagaa tatcttcatg aacatccaca actttatgtc tatgaaagat
    44941 atttagaaga tgaacaatat cttattatgg taaacttaac agaatcactt gctgactatg
    45001 aacttccaaa agaagcagat cagtcctgga cattactctt gtcaaattcc tctagcggag
    45061 aatttgaagc taaaggcata ctagcacctt atgaagctcg gttatataaa acaaacaagt
    45121 aaaacttcct cgttaaagtt cattagttgg actttgcgag gaagtttttc agattgctct
    45181 gtcaattact catttcaata attcgctcta ggaccaccga tatatttagg acgagagcga
    45241 agggctgtca cgtgagcttg tccaagggtt ttcaaacgag gtctgacagg tacttggaca
    45301 tgtttgatat gcataccgat tgatgtgtca ccgatatcga taccggcttg tccaactacg
    45361 tgttccactt cgacaggatc attgaactgg tcaaaagcag caacagaaca agcacctcca
    45421 gcatgtagtg caggaacaac agagacaatt tcgaaatttt ttgcttctgc cactgttcgt
    45481 tctactacta atgctcggtt caaatgttca caaccttgga cagctagcgc aatttcttta
    45541 ggatccaaca actcttttaa cgtacggatg atccattgac caacttccgc actggaattt
    45601 tttccaatat gtcctccaac gacttcgctt gtgctgcatc ctaaaacaaa aagatcacct
    45661 tttttcaagt gtgcctcagc caatatgtca ttaactattt cagtcaattg gtcttttaat
    45721 tctttttctg acaacttcat tttctaaaac cttctttttc aattaatatt gcttccgtgc
    45781 ttgaatacgt tgaagacttg cagttatagg aaaggcaagt cccattccaa tcagattttg
    45841 gaagatgttt cctggtatag aagccactcc agccggccaa tcatataaaa tccaaccggc
    45901 gataccatag ccgatgatca taactaagct tcctaataaa agccctaatc cccacatacg
    45961 agtagaagat ttgctgaaag aaccagcaac atatccttgt aacccgtgga tcactaatga
    46021 aaaaactgcc cactgcggat atcctgaaat caaatcgatc aatagaccac tggaagcacc
    46081 aacaactaat ccacccgttg gaccataaag aaaagcagcg gtatagatcc cggcctcgca
    46141 taatgtcaca aatccattcg tagccggtac agggatcaaa attgttaatg aaagggcaac
    46201 tgtcaacgca atcagcatag catagatcgt taattgctta gttttcattt ctcattcctc
    46261 ctttttgaat accgccagac cagacacttc cggtatgatc gttcatcagc acgccattag
    46321 aaatacaatg ggcaacaaat tttttacttt ctgctactgc tttggtaaaa tctgccccta
    46381 acacaagatt cgctgttatt gcagaagaaa aggcacaacc ggccccgttt actgttgtag
    46441 tgtcgatttt tttatgagaa aatacctcat aatgatcaat tgaatagaga agatccacag
    46501 cttcatctcc agccatcctt gtgccgcctt tgatcacaat gttttttgtt cctgaagcag
    46561 tgagttcttt agcgagatgg atcatttctg ttaacgaaga gggaagagct tgaccagaaa
    46621 gtaaagcagc ttctgccaaa ttaggcgtaa tcatcgtaac aagtggaaaa agttcttcga
    46681 tgagctgcga aatatacaat tgattgatca cagcttcagt ttctttgaat gccaaaacag
    46741 ggtctaaaat gattgggata ttttgttttg tttttatgaa gtctcgaaca accatgattg
    46801 cttcacttga attcaataac ccaattttga taccatctaa tgaagtcatt ttatcaatcg
    46861 aaactaactg tcgtttaagc aattccaaag atatagattc cagcataaat cgctcattaa
    46921 tatctagtgc ccctatagaa gtcaaggcgc ttagtccgaa tagaccaaaa ttctcaaaag
    46981 tttttaaatc tgtttggatt cctccaccag caaatggatc agaaccgcca attgtcaaga
    47041 ttcttttcat aacattttcc tccatgaata agagtataac gaaattttca aaaaagaaaa
    47101 acagccaatt ggcatatttt tatctcatcc aatttaaaaa aacaaaaaga aaagaaagac
    47161 caaaatggat ctttctttcc ttaaatagtt aggacttttg tgattttaat tctttctcga
    47221 tttgaagccg ttgcactttc attgtagctg ttcgcgggat tgcatcaaaa tcacggatga
    47281 tagggacgtt caagcgagga agttcatgga cttgctccca ccatcgattc caatccattt
    47341 ctttatcagg agctaaagca ataatcggtt gtggagaatg atttttatcc cttacaatca
    47401 ctacttctgc caaaaaatct aacgaatcta ataaaaagtc ttcaatagct aatgtactat
    47461 tgatcgtttc gatcaaatcc acttgccgat ctttcaaaaa taggtggcca tgcttatcca
    47521 taaaaccgta atctccgcta tcccaccaat cgccataaac attttcctgg aaccgtgcat
    47581 cttccttgta ataagtcaaa gcccgtcctt tagacagtaa ttgtatatga ccatctgtgt
    47641 tttcaggtag gacattccca actgaatctg taatccgagc gcttgtcatg tcttccagtc
    47701 caacgcccat atctcttgca tcacttgttt tcaaactctc tagtgtatga gccttaagaa
    47761 tcattggtcc gcattcactt tggccatata cttgaagaaa taccgcatcc tgtgccatcg
    47821 acgttcgcaa aaatgtcttc attgtctggt tgtttatagc atcaaaagtg gagtgatagt
    47881 atcggatacc cgaaaaagct tctggatgct ccttagcagt aaaacgccac tgaacaaagt
    47941 tattcggatg ggtctctagt gcaattggcc ggtgagcttc caacatatga acaacttttg
    48001 aactttgtgc gtttgctaaa ggcatcatag gaaatcccat ggacatcaaa gaagagatac
    48061 caatattgaa tctggaatgc actggagaga tgtgaaaagc gattaatttc ttttccgaaa
    48121 tttttgtgaa aactgttttt tgccatttcg tccgccatcc catagaatga gcagaatgac
    48181 aaataagttt agggatacca gttgtaccag aagtatgggt catataagaa atttcatttt
    48241 tgtctaaaaa tgattgagaa acagacaaag caggttgttc cattaaataa agaataggaa
//
LOCUS       DAFLWZ010000015        45669 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000015 DAFLWZ010000000
VERSION     DAFLWZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.015"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(227..2302)
                     /locus_tag="L1V38_000903"
     CDS             complement(227..2302)
                     /locus_tag="L1V38_000903"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1315467.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2304..3221)
                     /gene="glyQ"
                     /locus_tag="L1V38_000904"
     CDS             complement(2304..3221)
                     /gene="glyQ"
                     /locus_tag="L1V38_000904"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBN1315468.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3605..4417)
                     /gene="recO"
                     /locus_tag="L1V38_000905"
     CDS             complement(3605..4417)
                     /gene="recO"
                     /locus_tag="L1V38_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBN1315469.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4560..5459)
                     /gene="era"
                     /locus_tag="L1V38_000906"
     CDS             complement(4560..5459)
                     /gene="era"
                     /locus_tag="L1V38_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBN1315470.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5474..5869)
                     /locus_tag="L1V38_000907"
     CDS             complement(5474..5869)
                     /locus_tag="L1V38_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBN1315471.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5853..6329)
                     /gene="ybeY"
                     /locus_tag="L1V38_000908"
     CDS             complement(5853..6329)
                     /gene="ybeY"
                     /locus_tag="L1V38_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBN1315472.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6346..8538)
                     /locus_tag="L1V38_000909"
     CDS             complement(6346..8538)
                     /locus_tag="L1V38_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBN1315473.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8562..9533)
                     /locus_tag="L1V38_000910"
     CDS             complement(8562..9533)
                     /locus_tag="L1V38_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBN1315474.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10239..11618
                     /gene="brnQ"
                     /locus_tag="L1V38_000911"
     CDS             10239..11618
                     /gene="brnQ"
                     /locus_tag="L1V38_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1315475.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11774..12220)
                     /locus_tag="L1V38_000912"
     CDS             complement(11774..12220)
                     /locus_tag="L1V38_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBN1315476.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12247..12423)
                     /locus_tag="L1V38_000913"
     CDS             complement(12247..12423)
                     /locus_tag="L1V38_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBN1315477.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12585..13013)
                     /locus_tag="L1V38_000914"
     CDS             complement(12585..13013)
                     /locus_tag="L1V38_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1315478.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13105..13965
                     /locus_tag="L1V38_000915"
     CDS             13105..13965
                     /locus_tag="L1V38_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBN1315479.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(14049..14399)
                     /locus_tag="L1V38_000916"
     CDS             complement(14049..14399)
                     /locus_tag="L1V38_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1315480.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14415..16142)
                     /locus_tag="L1V38_000917"
     CDS             complement(14415..16142)
                     /locus_tag="L1V38_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBN1315481.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16355..17281)
                     /gene="trxB"
                     /locus_tag="L1V38_000918"
     CDS             complement(16355..17281)
                     /gene="trxB"
                     /locus_tag="L1V38_000918"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBN1315482.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17426..18862)
                     /locus_tag="L1V38_000919"
     CDS             complement(17426..18862)
                     /locus_tag="L1V38_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1315483.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(18859..20262)
                     /locus_tag="L1V38_000920"
     CDS             complement(18859..20262)
                     /locus_tag="L1V38_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1315484.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20492..21394
                     /locus_tag="L1V38_000921"
     CDS             20492..21394
                     /locus_tag="L1V38_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1315485.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21435..23321)
                     /locus_tag="L1V38_000922"
     CDS             complement(21435..23321)
                     /locus_tag="L1V38_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1315486.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23418..24269)
                     /locus_tag="L1V38_000923"
     CDS             complement(23418..24269)
                     /locus_tag="L1V38_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1315487.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24727..26511)
                     /locus_tag="L1V38_000924"
     CDS             complement(24727..26511)
                     /locus_tag="L1V38_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315488.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26511..28262)
                     /locus_tag="L1V38_000925"
     CDS             complement(26511..28262)
                     /locus_tag="L1V38_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315489.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28404..28628)
                     /locus_tag="L1V38_000926"
     CDS             complement(28404..28628)
                     /locus_tag="L1V38_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBN1315490.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            28879..30465
                     /locus_tag="L1V38_000927"
     CDS             28879..30465
                     /locus_tag="L1V38_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBN1315491.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(30912..32129)
                     /locus_tag="L1V38_000928"
     CDS             complement(30912..32129)
                     /locus_tag="L1V38_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1315492.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(32386..34161)
                     /locus_tag="L1V38_000929"
     CDS             complement(32386..34161)
                     /locus_tag="L1V38_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBN1315493.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(34374..35276)
                     /locus_tag="L1V38_000930"
     CDS             complement(34374..35276)
                     /locus_tag="L1V38_000930"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBN1315494.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            35555..37900
                     /locus_tag="L1V38_000931"
     CDS             35555..37900
                     /locus_tag="L1V38_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1315495.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            complement(38203..39204)
                     /gene="ccpA"
                     /locus_tag="L1V38_000932"
     CDS             complement(38203..39204)
                     /gene="ccpA"
                     /locus_tag="L1V38_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBN1315496.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            39414..40520
                     /locus_tag="L1V38_000933"
     CDS             39414..40520
                     /locus_tag="L1V38_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1315497.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            complement(40588..41190)
                     /locus_tag="L1V38_000934"
     CDS             complement(40588..41190)
                     /locus_tag="L1V38_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1315498.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(41193..41633)
                     /locus_tag="L1V38_000935"
     CDS             complement(41193..41633)
                     /locus_tag="L1V38_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBN1315499.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            complement(41758..42696)
                     /gene="galU"
                     /locus_tag="L1V38_000936"
     CDS             complement(41758..42696)
                     /gene="galU"
                     /locus_tag="L1V38_000936"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1315500.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            complement(42711..43736)
                     /locus_tag="L1V38_000937"
     CDS             complement(42711..43736)
                     /locus_tag="L1V38_000937"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1315501.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(43780..44610)
                     /locus_tag="L1V38_000938"
     CDS             complement(43780..44610)
                     /locus_tag="L1V38_000938"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBN1315502.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            complement(44625..45563)
                     /locus_tag="L1V38_000939"
     CDS             complement(44625..45563)
                     /locus_tag="L1V38_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBN1315503.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT        12919 a         9671 c         8256 g        14823 t
ORIGIN      
        1 tagggcaatt tacgatttaa aagtaaataa aacattaata agataacaat taatcgattt
       61 catttttatt tccttaattt tcataggtgt ttttaaaagt tacacaaaaa ataaaataac
      121 aaaaaaatta acattgaatt aataatagtt atttatattt ataacaaata aaccagagaa
      181 atagcctatt ttgtgcctgt tctctggttt atttacatat tagaaattat tttgtgatga
      241 tttgatctaa acttgctagt gacaaagcca tggcagcaat ttgacttaat tgcgttaatc
      301 ggttcttacg tactgctggt tcttctgcca tgaccatcgt ctgatcaaaa taattttcga
      361 tcagtgggcg aaggcttaca agctgatcat aattttcgtt gatcgtttgg tcagcaaagc
      421 ttgttttcat tgcctctact gctttgtgca gttctttctc cgcttcgttt tcgaacagtt
      481 cagggtctac ttctgattgt ttttcaagct ccgctttttt cgctaagttc acgacacgtg
      541 tcaaagcttc catcgatggt ttgaagtctt catctgcaag atgctgcttg aacaattgtg
      601 ctgctgcaaa tacttttgtc agatcttttt gttctgcatt caaaacagct tcgatgacat
      661 catgacggat attcttcgtt gtcaataatt ggcgcagacg gcctttgata aagtcgatca
      721 cctgttgttg tcccgctgac aagccaatgc caaaacgatc cgtatcttta ctgataactt
      781 cactaatcgt ttcttgcaga acagacaaag gaaaggccca ttttttcgat tcgatgattc
      841 gaacgacacc atatgcttga cggcgcaaag catatggatc gtttgagcca cttgggatca
      901 tcccaactgc aaagaaagaa aagatactat ctaatttatc agcaatcgct aaaacagaac
      961 ctactgtagt ctcaggtaaa tctccttcac tggatatagg catgtaatgt tcacggatcg
     1021 ctgttgctac ggctggtttc tcgcctttca gcagagcata tttttctccc atgatccctt
     1081 gtagttcagg gaattctcct accatgttgg ttactagatc aaatttatag atttcagcag
     1141 cgcgttgcag atccatcaat tcttcctcag atagtcctac ttgttcgcct atgatgcgag
     1201 cgatgacttg tacccgttgc attttctcat agatgctacc gattttttca tggaaagtaa
     1261 cagtttttaa tttttcaacg tattggtcga ttgaagcttt cttgtcttca ttataaaaga
     1321 attccgcatc ttctaaacga gccgtcaata ctttttgatt gcctcgtacc acattttcca
     1381 attttacccg atcgccatta cgagcagaaa taaaatgagg aagcaacata ccttgatcgt
     1441 tccgtacttc gaaataacgt tgatgttctt tcatagaagt gactagtact tcttcaggaa
     1501 cagatagata tttttcttcg aagtcgccag aaaagacagt tggatattcg actaaattgt
     1561 tgacttcttc tagtaaatct tcatctagat caatgatcca gtgatttttt tcggctaatt
     1621 cgtttgcttg tgtgatgatc atttcttttc ttttttgcgg tgaagcaata acaaattgtt
     1681 cattcaattt ttcttcgtat tcttttgcat gcgtaaatgt cacatcttcg cctaagaaac
     1741 gatgacctct tgaagctctg tctgttttga catccaagat ctcaaacggg attatttcgt
     1801 catctaacaa tgccacgatc cagtgaatag ggcgaatata ttcaaaatcg tattctgccc
     1861 agtgcatcgt tactgggaaa gtgaggcttt taatgacatc tgctaaacct gtcaatactt
     1921 cttttgcttc tttgccgtga gtgtatttcg ttacatagac atattccacg ccttttaatt
     1981 ctctaaaagt gatagcatct gtcgtcagac cttgtccgcg gacaaatcct tcagctgctt
     2041 tcgtccagtt tccatctgcg tccaaagcaa tttttttggc tggtcctttg acttcttctt
     2101 cgctgtctgc ttgacgttct ggaatgtttg ttactttgat tgctaagcgg cgcggtgtag
     2161 aaaacgtttc gatcgtatca taagtcaatt ggttttcatc taaaaatttt gctgtttttt
     2221 cttctaattg tttcatgctt ggtgtgacaa catgagcagg catttcttcc agcccgattt
     2281 caagtaataa gtcttttgcc atcttattca gcctccttca tgttttctgg atttgctgtg
     2341 tttttattca ataaagggaa tcctaatttt tcgcgttctg ccacaaagat tttggctaca
     2401 gcacgagcca tgttgcggat acgggaaaga taacctgctc gttctgttac ggatactgca
     2461 ccgcgagcat ctaataaatt gaatgtatgg ctgcatttca aaatataatc atacgctgga
     2521 tgaacaagat tttcatcgat acagcgttta gcttcttttt caaaacggtc aaagttgctt
     2581 agtagcaagt cttggtcact tacttcaaaa gaatatttgg aatgttcata ttctggttgt
     2641 ttgaagatct cgccatattt cacaccatca gcccattcca gatcatagac actttcaact
     2701 tcttgaatat atgaagcaag acgttctagt ccataagtga tctcagaagt aactggttta
     2761 caaggtagtc ctccgacttg ctggaagtac gtgaattgtg tgatctccat cccatcaagc
     2821 catacttccc aacccacacc ggcacacccc atcgatgggt tctcccagtt gtcttcaaca
     2881 aaacgaatat cgtgttctaa tggatcaatt cctaaaagac gcaagctttc taaataaagc
     2941 tcttggatat tttcaggtga aggtttcatt acgacttgaa attgatgatg ctgatacaaa
     3001 cggtttgggt tttctccata acgcccgtca gctggtcggc gggatggctc tacataagca
     3061 gcattccatg gttccggtcc gattgcccgt aagaatgtat atgggctcat cgtacctgct
     3121 cctttttctg tgtcataagc ttgcatcagc atgcagccgt ttgatgacca aaatttttgt
     3181 aatgttaaaa tcatatcttg gacggtcaat tttttactca tctgttttgc ccctttcaat
     3241 ttttaagcgt tgctgtcaat aagaatacag gaaagaaaac gacaaaaagt ccctatgtct
     3301 gattacagac atagggacga ataatttcgc ggttccaccc tacttccgaa taaagattcg
     3361 gcagcttcat ttatcgtact cgcaagtgcc tcttcaaaaa tcgtttgggt ccggcttcca
     3421 ctctcccgaa ctcgctaaac cacgtgtttt ttactgatct tggtcaatgt acgtattcat
     3481 tttgcagttt tcttgtttat ataatagatc ctctcagtga acgatctatt taatctacgg
     3541 ttaataatag acggaagtcc ctgtatttgt caaatagttt tgattttttt gttgtatctt
     3601 tcatttattc ttctttttca ggtatctctt tttcaggcat atttttctct ggcgtcttta
     3661 atacgtgtgc ccaagacttc atttgatcaa tgaacttttt gctttttaga tgaataccga
     3721 catattcatc atacaactgg tcaatgaggt cacggattgc ctgcttcgtt tcttctttca
     3781 agtggattcc actgatctta tcataagaaa tagccgaaaa cattcgaacg aaataaacag
     3841 cgcgaggatc tgcatgataa cggtgttcgt ccattggcca gtgtttctcg catatcacac
     3901 cgccagattt ggaagaatag tcaaattttc cttttgtttc cccgcatacg acacagtgcg
     3961 tccaaattgg cgcgattccg aagcgttgca gtatttgaac ttcaaagata ttcgtgatga
     4021 tttctgcatc atctccttga tccatccgct gcagagcttg ttgcgtaaat tggaataaat
     4081 gcgggtcata ttgatgatct tcgattgctg catctactag atttagcaaa taggtaccat
     4141 aaccgctcaa aaagatatct tcttggatgt tccgaaacgc atggacgtct ttgacactgc
     4201 ttaaaaacga caaaccttca cttcgaaaat taccgatata gactgcttcg gtaaagggga
     4261 gcaaagccgg agctaatggc tgattttgcc gatggattcc tttgatataa aacatcattt
     4321 tgccagaaga ttccgtaaag attttgacta atttatcttt ttctttgtaa ttacggctag
     4381 ataaaatcaa gcctttcgat tctgcaagct ggctcatatt ctccctccta aaaaataaat
     4441 ctggaaaagc agattctgcc gatccagatt atttatgttt cgatcttccg ccgtttttct
     4501 caacgtgcgg atttttatcc agtttatttc tatacttaac ctataagaag ttcagaatat
     4561 cagtattcgt cttttcggta gccaaagtct tgcagataga cttttttgtc tcgccagtct
     4621 ttttggactt tgacccaaag ttctagaaat actttgtctc ctaaaagatt ttcgatatcc
     4681 tttcttgctt tcgttcctac ttgcttcagc atttttccgc ctttgccgat aatgattcct
     4741 ttttggctat ctctttcgac gatgatcgtg gcctggatat ggattttatc attctcgttt
     4801 cgcttcatcg aatcaacaac gactgcgaca gaatgaggca cttcgtctcg tgttaaaaac
     4861 aagactttct cacggatcaa ttcagaaacg ataaagtatt caggatgatc agtcacttga
     4921 tcatctggaa aatattgtgg gccctctggc atttcactga ctaatacatc cattaagcgt
     4981 tcgacattgt ttccttctgt agcagagatc ggaatcactt gtgcaaaagg catctgcgtc
     5041 gaataatctt cgatgattcc cagcaactcg tctggatgga tcttatcgat tttattgata
     5101 atcagataaa ctggagaatg cacgtttttt agacgttcaa taataaaatc gtctccccgg
     5161 ccgcgttttt gatcagcact gatcataaat aagactgcat ccacttcttt caacgcactg
     5221 taagctgctt ctaccataaa atctcctaga cgatgctttg gtttatggat tcctggtgta
     5281 tcgataaaaa tcagctgagc ttctggtgta gtatatactc cttggatttt atttctagtt
     5341 gtctgtgcct tgtcactcat aatggcaatt ttttgaccca cgattcggtt caataatgtg
     5401 gattttccta cattcgggcg gccgacgatt gcgacaaacc ctgatttatg ttctggcata
     5461 tacgttctcc tttttaatta aacaacaaat gatatatttt agggacaaat aaaatcaacc
     5521 caatgatgac agcaaaacaa gcggtcacta aaactgctcc agctgccata tctttgattt
     5581 ttttcccaat cggatgaaaa tgaaaatccg taaacatgtc cactacattt tcaaaaacag
     5641 tattgatgat ctctactatc caaacgagaa aaacagctaa aagcagccat aaccactcta
     5701 tccgatcaag ctggaaaatc acgcccataa ataaagcaag gataccgaac gcaacatgtt
     5761 tcctcatatt gcgttcttcc tcaaaaacgg ttttgactcc ttggacagca aattccacag
     5821 acatcaggaa atgtttgttt ttctctacgt ttttatcttt tgagtccata ggcatccaag
     5881 atctctttct gtaaaccaaa catttctttc tcatcttctg gtgtcatatg gtcatacccg
     5941 ttgatatgca agaatccatg taccgctaaa aagccaagtt cccgatcata tgaatggccg
     6001 taagcttctg cttgttcagc agcacgttca atagaaatca tgatgtctcc tagtacacga
     6061 ggcaaaggat tctctccatc ttcaaaaatc actgggattt cgtcttcgcc ttcttcttcc
     6121 agagcaaaac tgatgacgtc tgtcggtgca tcttttccac ggtaatcacg attgattact
     6181 tggattgccg cattgtccat gaaagtaaca gacatttctg tttcctctgg cagctttaaa
     6241 taagatgctg caaattgcag caagtcatcg atttctttca ttttctcttc tgagacttgg
     6301 tttgtttcat ccataaaggt aatatccatt atacatcgct tctttctatt cttcttgttc
     6361 ttcctttatc ttctcaactt ctgttttcat tttaggatat ttgatccgag aatggaaggt
     6421 gctacttaaa ccgctgatca atgatttttc cacttttcgg atttctttca aggtcagtcc
     6481 actatcgtct aattgaccat cggaaatacg ctcttcgata agattatgga caaaactttc
     6541 gattttttcg ctcgtcggat gatccattgc ccgtactgca gcctcacaac tgtcagcaat
     6601 attgacgatc cctgcttcac gactttgcgg ttttggtcca ggataacgga attgctcttc
     6661 tgttacttcc ggattgcgtt ctttcgcttt gatgtagaaa taacgcatta gcgtggttcc
     6721 atgatgctgt ttgcaaatat cgatcaccat ttgcggcata ttataatctt ccaatatttt
     6781 ggctccatct gtcacatgtc caaagataat atgtttactg tcttctggca ataagaaatt
     6841 gtgcgggttt tccgctcctg aaggcaagtt ctcaacgaaa aagctagcat gtttgatctt
     6901 gccgatatca tgataatagc aagctactcg agttagcaaa gaacgtccgc cgatttctgc
     6961 tacagcgtta gcacttagat tagctaccat catactatga tgataagtac ctggcgcttc
     7021 ttccagcaac tgtttcaata aaggatgatt tggattgctg agttcattta atacaattac
     7081 actgtcatca ttgaccatca attcaatata tgggtgtaga ccgatcgtca gcaagaatga
     7141 gaagagtgca ccagtgaacc cgcagacaag cattaaccaa gtcgttgcat caccaaagct
     7201 cattccttga tagacgatca aaatgacatc catcatcaca ggaaaaataa tgacccacat
     7261 ggcagcagat aatccttgtt ctgagatccg tttgcgtctg acaatcgttg ccatgagccc
     7321 agagaaaaca taagacatca agataatcgt tagaaagttc gtgccaatcg aatcataaaa
     7381 aatgaaaagt gcagatactg cttggaaaat accagccatg atccctgctc ttcggttcaa
     7441 gaaaaagctt aaaacaagtg gtgcaaaagc agcgggataa aacagcggga tataagtagc
     7501 ttgttccgtt tggaataatt ggaaaaattt catcagcact atgctgactg acatagctgt
     7561 cacatagaaa agcacgtatt ttgttctttc tcctgcattt tggaattgaa gtgaattata
     7621 aatcagtacg ccgatttgaa gcaaaacagc taaaaccatg gcaatgagtg ggaaaatcga
     7681 agtcgtttga ttcgtcaatc ctagtaattc caattttttc atcgctgaag catcaatttg
     7741 atttccttcg cgaacaatga tttctccttg gaagatcatc actggttgta cagcttctcg
     7801 tgcagattgt tttaattctt ctgtcttttt ctcattcaat acatcattga ctacaatgcc
     7861 ttgatccact aagtagcgaa tcatttgttg ctgctctgtt gtgacattca aatactgaat
     7921 ctgatcttct gcttcttgtt taaaagcttc caattcgctt tcacgaactt gtttactcat
     7981 ctgttcgtca atgagcttca aactttcatc cctaaccgtg tgaatttccg tttcagtcat
     8041 ttcaaatatc gtcgaataaa aattgttcgg cagtttttgg taaaacgcaa cgttttctgc
     8101 attcacgttt tcaaaatttt tcttcagtgt agcaatccgc tcttctgtag taggtttcgg
     8161 gatattttca tcttccttcg ccttatctac cttgtcatta taagatttgt tgatggtatc
     8221 attcgtctta tcgatcaatt cgaataattg cttgatccga ttgttctggt catctgccag
     8281 atctttttga taagtatatt ctggagtcac tgcttctgct gccagttttc ttctttgttc
     8341 ggtttcttcc gtgttctcga tcgttttatt cgcacggata ctctcttctg ctacttggcc
     8401 ttctctgaaa tcattggcct tttgtttgac actactaaat gtaacgccgc agacaatgat
     8461 aaaaaacaag aacagaagga aaggcaatgc tgcctttccg agtttttctt gtagtttctg
     8521 cagtgtttta ttcaacatgt gcttatcctc ctaagcaaag cttattcttg atgaagatcc
     8581 gccttttcat aagctttgat gatttcggca actacagggt gccgaacaac gtcacttgct
     8641 tcaaaattaa caaaatcgat ttttttgatt tgctttagtg ttcgttctgc atgaacaaga
     8701 ccacttgtcg tccctcgagg caagtctatc tgacttgtat ccccattgac aatcattttt
     8761 gattgataac cgagacgggt caagaacatt ttcatctgag cgactgtcgt gttttgtgct
     8821 tcgtccaaga taacgaatgc atcatccaat gtccgccccc gcatgtaagc taatggtgcg
     8881 atttcgatta cgcctcgttc catcaatcgg ttcgtatgat ccaatccaaa aatttggtat
     8941 aaagcatcat aaacaggccg cagataagga tccacttttt ctttcagatc cccgggtaga
     9001 aagcctaggt tttcccctgc ctctacagcg ggccgcgtca aaatgatttt ttgcacttcg
     9061 ccttttttta gggcagcaat tgctaatact acggcaagaa acgttttccc tgttccggct
     9121 ggccctacac caaatacgat gtcatgtttg gctaccgatt caacgtattt cttttgaccg
     9181 ctgtttttta cccgtatagg ttttccatta cggtctttga cgatctcttc ctcatacatc
     9241 tcaacaaaat aatctaatgt acctttttgc cccattttca atgccgtcac gacatctggt
     9301 gtacttacgt ggattcctcg tttgatcaat tcctgtaatg tccgaatgac tgaggcagcc
     9361 aaggaaatct gggattgttc accaatgatc tgaatgattt ctccacgtgt atggatggtt
     9421 gtttccgttg tttcctcgat cagttttata tgcttgtcgt gtgcacctaa aagcatgctg
     9481 acatcatcag cagctgtcaa tctaatctct aaagaactag actcttccgt caaaaataga
     9541 catccccttt ttttcgattc attctttcct attttaccat actcagaaga aactatatag
     9601 caaataagaa aaggttgtaa aagagtcgtt taaccatacg taccaagaaa cgttaaaaaa
     9661 tagctgtttc cattcgctaa aggtctcgtt ttgataaaaa gaatctgaga atgtaagtta
     9721 tatgaaagtg gagaacaaaa tattccgttt cattcagagg tattctctag gtatttttct
     9781 tgtttcaaaa aaagaaaaca aaatagttaa aatattcttg catttcaaaa aaaacaggtg
     9841 tattattacg tcaacaaata aacatacagc aaagcgtcga ggaaaacagt aggctattca
     9901 acgatttatt cccagtgagt catgtaagtg agaaatgaca ataaatcgaa tagacgaaca
     9961 tcatttccga gtcaatgtcg aaaacgtaga tcattgtggc tgcctccatt atcaggctag
    10021 cggataactt tatcaaaaag cgtccgtgaa tgaagaagct tttttaagcg aaaaaaggtg
    10081 gtaccgttct agaatctaga gcccttttcc caagtggaaa agggcttttt tttatatttt
    10141 aaggtggtgg ttttcatgga atctgatatt agtggcatta ctaattgctg caacgtttat
    10201 atcgtcaatc aaaatgataa ttattggagg aaaaatttat ggaagaaaca aaaacttatt
    10261 catggaaaca actattgatg gtcagttcac ttatcttcgg gatgtttttc gggtcaggta
    10321 atctaatctt tcctgtccac ttaggtcaaa tggctggcgc aaactgggtc agtgctggcg
    10381 taggatttgc catctcaggc gctcttttcc cattactagc tatcttagct gtagtagtga
    10441 caaaaagtga tggtctgtat gacttagcta aacctgtcgg aaaatggtat gctgccttgt
    10501 tcttaatcct tgttcatttg acgatcggac catttttcgg tacaccacgg acagctgcta
    10561 ctgcttttga aatggctgct aaaccatttt tgcctgaaaa atataattca ttaggtatgt
    10621 ttttattctc tgctcttttc tttttacttg cttatttcct tactgtccat cccacacggt
    10681 tggtcaaata cgtcggaaag tatctaaact ccttgtttct tgcattatta gcaatcattt
    10741 ttgtcgtttc tttattccac ccaatgggaa atctaaatca atctgctgca gatacttacc
    10801 aaacaaacgc tttaacaaat ggtgtcctag aaggttataa cacggttgat gcagtagcct
    10861 tgcttgcctt aagtgtcact tttgtccatg cagtccgtga ccttggtttc aaagataaaa
    10921 aagtcacaga attaacagca aaagctggta gcctgagcgt tgcgctagaa gtcatgatct
    10981 attttggtct tgttcttctc ggtgcgatga gtttgaataa gatgtcttta tcagaaaatg
    11041 gcggaactgc actttctcag atcactaatt tttatttagg taacttcggc gctagcttct
    11101 taggagtgat ggtcacatta ggtgtcttca ctaccgctat gggactcgtt gtttcttttg
    11161 cacaagattt ccataaactg ttccctaaag tcagttatat gacatggctg cggttaacga
    11221 ctttcgtctc ttttgtcgtt gcaaatgctg gtttggacaa tatcatccaa tggtctttac
    11281 cagtattgat gcttttgtat ccattgtcgc ttgcgttgat tttgctttcc ttaacagcaa
    11341 aatttttcca aaagacacca tttgtctatc aagtaacgat gttgtttgct gctgttcccg
    11401 ccgtattgga tatgctggca aattcgcctg ctttagtgag tcaacaaaga gttgtagcaa
    11461 gcatgctcga attttatcat catcacgttc cttttgctgc attgggactt ggctggatgg
    11521 tcccaacgtt acttgggtat gctggcagct tactcttcta ttacgcctat cgcctatcag
    11581 ggtataaaca agaagcaaat gaactaccag aagaataacc agatcaaaca caatttaaca
    11641 taagaaatat taaacaggaa aaaaacagct agatgaaaga atcctattct ttcgtctagc
    11701 tattttttag atctcttttt tacgagcaca aaaaaactgc ggacaatgat tgtccgcagt
    11761 ttaaatgata aaattaagat tgtaatagtt ctttcacaat ggcatttact tggtttccat
    11821 ctgcttttcc tttgacttta ggcatgatcg cacccatgac tttgccaaat tctttcattg
    11881 atgaagcacc agtttgcgtg attgcttctt gaacaagttg tcgaatttct tcgtcggaaa
    11941 gttgttccgg catgtatttt tcgactatca caatttcact ttttactttt tcagctaaat
    12001 cgtcacgtcc tgcttcttca aactcatgca aagaatcacg tcgctgtttc atttcgcgag
    12061 acaacaccgt taattcttct tcttctgtca agtcgtgacc ttctttaatc tgctcgtttt
    12121 gtatagatga cttgatcatt cggatgactt gtaaagattc cttatctttc gctttcatcg
    12181 ctgttttcat gtcatcgttt aatctactta gtagtgacac actaccaact ccaattcatc
    12241 acagaactag aattttttgc gttttctagc tgcttcagat tttttcttgc gtcttacact
    12301 tggtttttcg tagaattcac gtttacgaga ttcttgtaaa gtacccgctt ttgacacgga
    12361 acgtttgaag cgacgaagag catcgtcaag tgattcgttt ttgcgaacga ctgtttttga
    12421 catgttaatt ccctccctcc gagcttaaaa agtaaccgta attgttattg aaatatatct
    12481 caaaaaacaa gactgtcctg taaatattat atctaatgct gttttgaccg tcaaggaaat
    12541 cttgcttttt tttaaaatta tcaaatgtta ttttatttaa atccttattg acaattttca
    12601 catcttccga aaatctcgaa tctatgccct tcgatcgtac atccaccgag ctgttcttcg
    12661 aaataattca ttggacacat atggatttct ttcgttgttc cgcacaccgt acagataaag
    12721 tgatggtgat ggccgatttc cccttgacag caatgaaaac gaaacttcat ctctccattt
    12781 aaatcggttt cttccagtaa atcgatttct gcaaaatcat ggagatttcg ataaatcgta
    12841 tcgtaactta ctcctttgaa ttcctgattc atatagtcaa aaacttcttt agcggatacg
    12901 tagcgattgc gcttcactaa ataagttaac aatgcttctc tttttttagt atatttaaaa
    12961 ccgttatttt tcaatgtttc tagtgattgt tcgatcaacg tctgtttttt catgacttat
    13021 tcctccaaat caaaatgatt acgaagtaca cattctagag tatggtataa taaacataaa
    13081 aaaaatgcaa gtgaggtttt atccatgtct tccgattcta cagaaatcgt tacttttttt
    13141 gtcatctccg actctgctgg agaaactgcg acaaaactag cgcaagccac tatggcccaa
    13201 tatcctagcg ttgagttcaa tttattccgc agaacatttg tgacagatga gaaaacattg
    13261 atgcaggcac tgcaagatgc actagaagaa aaagctcttg tcctgcacac attgatcaat
    13321 caagaattga tcgagatgac gcgttctttt tgtgaagaac atcaattatt tagttttgat
    13381 gtgatgactc cgccgatatc agaaatcgag cgcttaactg gtatcaagcc cattcggcaa
    13441 cctggcgccc ttcatttatt gaatgagaac tatttcaaac ggatcaaagc aatggaattt
    13501 gctgtaaaat acgatgacgg gaaagatcct cgtgggtttc tagaagcaga tgtcgttttg
    13561 ctaggcgtat cccgaacttc caaaacgcct ttgagcttgt ttttagctaa caaaaattta
    13621 aaagttgcca atctaccttt gatcccacaa gcacatattc ccaaacagct ttgggagatc
    13681 gatcctaaaa aaatcgtggg actgacgaat aacccagata ttttaaacaa tatccgtaaa
    13741 gaacggatgc gctcttacgg attaaatcct gatactgctt attccgatat cgaaaaaata
    13801 cgagctgaac tcgattttgc gaatgatctt tatgaaaaat tgggctgcgt agtaatcaat
    13861 gtcgcttctt tatctattga agaaacagct tcgcttattt tgaatgcttt agacctagaa
    13921 gaccatagtt attatggaac tgaaaccacc gaagaaacag actaacaatt tttctttaaa
    13981 aaaactggac tgtgtcagcg aagaagattc gttgacacag tccagtttgt ctctatttgc
    14041 acctatcgtt attgatgttc cacatgtttg agtgtctggt tcaaaatatc cagtacgtga
    14101 gaatcatcaa gactatacaa aatcgctttt ccctcacgat gggacttgac gacatggttt
    14161 tctcttaata aacgcagttg atgcgataca gcagattgtt ccatttccac tgcttggatg
    14221 attgctgtca cattttgttc cccgtctttc agatacagca gaattttgag acgagtgggg
    14281 tcactcaaca ttttgaatag ttggctgact ttctctactt ttgttttttg cgtgtctggc
    14341 aatccattca cctccaactt gaaaaaagac tgacttctaa agtttaccac tttttccatc
    14401 agtctcaagt ttttttattc ttctgtcatc ttttggataa tcgtttcata agcggctact
    14461 ttttcagctg cgtcttctga agagtttcct tttacaccga tataaaattt gattttcggc
    14521 tcagttcctg aaggacggat agcgatccag ccattttctt ccagcgtata cttcaatacg
    14581 tcagatggcg gtgtcgttag tttttctacg tttccttcac ggtctgttct cgtcaactct
    14641 ttgaagtctt ctgtttggat gacttttgct ccggcaaatt ctgttggtgc ttcttcacgg
    14701 aatttttcca tcaaagcaga gattttcgca gaaccttctt gtccgctcat tgtcacagaa
    14761 atcgtttttt ctgcgtagta gccataggtt tcaaaaatcg tttgcaagcc atcatacaac
    14821 gttttgcctt gttttttata gtaagctgct acttctgcta ataagagcaa tgcttggatc
    14881 gcgtctttgt cgcgaacgaa aggtttaact aaataaccgt aactttcttc gaatccgaac
    14941 ataaaagtat gggaatgatc ttcttcaaat tgttgaattt tttcagcaat gaatttgaat
    15001 cctgtcaata cattgaacat ggtagcccca tagtgttccg caattgctgt aggtaattcg
    15061 ctagaaacga tcgatttcaa taccgctgcg ttttcaggta aagtgcctcg cgattggtgt
    15121 gcttccaaaa tatattgagc aaacagtgct ccgatttggt ttccggtcaa tacttcatag
    15181 gagccatttg gcaaacgaac ggctgcacct aaacggtctg catcaggatc tgttgcaatc
    15241 agcaaatcag cgccttcttt ctcgccaagt cgtatcgcat actcaaaagc agagtgttct
    15301 tctggatttg gtgatttgac tgtagtgaaa tctgggtctg cgacagcttg ttctggaact
    15361 agtacgaatt gttcgaatcc agcttgtttc aacgcacgtt cgcccaacat ttttcctgtt
    15421 ccgtgaagtg gtgtgtacac aagtttcaaa tctttcccca ttgtttccac caattcatga
    15481 tcaatcgtta ctgctttgat ttcttctaga taagcggcat ccacttcttc tccgatgatc
    15541 gtgatcaatc cgctatgttc agcttcttcg tcagataata cttcaacttt taacggattg
    15601 ctgacttcac ggacatattt cgtcaatgca tctgcgtctg caggaggcat ttgtccccca
    15661 tcttctccgt agactttata tccgttgtaa gctgctggat tgtgggatgc ggttaccatg
    15721 attcccgcaa acgtcttcaa atgacggact gcaaaagaaa gctctggtgt tggacgtaga
    15781 ctttcgaata cataagatgg gatattgtga tgtgctaatg ttttggctgc ttccatggca
    15841 aattctggtg attgatggcg tgagtcataa gcgatagcga cacctcggcg ttttgtttct
    15901 tcgccttgtg tatccatgaa acgtgcaagt ccttctgttg cttgtcttac cgtatagatg
    15961 ttcattcgat tgatcccagg ccctaagatt ccccgcatgc ctgcagtacc gaattccaac
    16021 ggtgcataaa aagcatcttc aagtttttca ggatcttcac ccagatcatt taattgtttt
    16081 tttaagtttt cttctaaatt ttcttcatgt acccattgtt catacacttg ttcccaagac
    16141 atgaaaataa cacctctttc tgaaatatgg ttcttaataa gtatagcatt cacttattag
    16201 atatgaaagt atgaggacca aaaaacgctt aaatcaagaa aggattcttt tatcaagcac
    16261 ggttgcaagt attcgcataa atcggattca gtagatttca cgcgaaaaaa aagagtaaaa
    16321 gaacaattaa accgttcttc cactcttttt aaacttatgc agttgtttct tctaaagatt
    16381 ccaagtattt atacacttgt tgtccagcga tcccaccatc accaacagca gtagtgattt
    16441 gtcgcaaatc tttttcacga acatctccga tggcaaaaac gcctggtata ttcgtcttca
    16501 tttcgttgtc tgttggaatc cagccagctt cgttcgtcaa ccctgcttct ctaaatggtg
    16561 cagttaatgg atccagtcca acatagatga atactccgtc tgctgccaaa tcaaactcat
    16621 tgccggtttt gacattacgt gctttcacac ctgtcactac catttcattc ccaacgattt
    16681 cgtcaacgac tgtatcccac ataaaggaaa ttttttcatt cgcaaatgca cggtcttgga
    16741 tgatcttttg tgcacgtaat tcatctctac ggtggacgat gactacttca gaagcaaatt
    16801 gtgtcaaata gatggcttct tctactgctg agtctcctcc tccgatcact actagacgtt
    16861 tgttacggaa aaacgcacca tcacaaactg cacagtaaga aacgccacgt ccagcaaatt
    16921 cttcctcgcc aggtacgcct aatttacggt ggatacagcc tgttgcgata atgactgttt
    16981 ttccttcgta agttttatct tcacaaataa cttctttgtg gctgccgtga tccttgatat
    17041 cttgcacgat tccataagca ttttctgtcc caaatcttga aacaccttca tacatcttat
    17101 aagctagatc aggacccatt attgaatcga aaccaggata gttttcgatt tctgccgtat
    17161 tgttcatttg gccgccaggg gcgccttgtt cgatcatcaa tacggataag tttgaacgtg
    17221 aagcatataa agcagcagtc atcccagcag gacctgcgcc aataacgatt acatcataca
    17281 tatgtagatt ctcctttact taatcaagta agcatacttt acagccaatg cgaaaaaaag
    17341 tctattgttc tgcttgcgtt tctcgaatag ctttattata ctcgaaaaat ccgctgaaaa
    17401 acaatagact tttataaatc attgatcaat cattcgaaag attttctcca tttgaatcaa
    17461 ttactttttt ataccagttg aatgatttct tcttcgaacg ggctaatgtg ccatttcctt
    17521 cgttgtcacg atcgacataa atgaatccgt accttttctt catctcacct gtaccagctg
    17581 atactaaatc aatacatccc caagtcgtat agcctaatag atcgactcca tctaattcta
    17641 ctgcatcttt cattgcctgg atatgtgctg ccagatagtc gattcgatag tcatcttcca
    17701 cataaccatt ctcatcgggc gtatcgactg cacctaagcc gttttctaca ataaatagtg
    17761 gtttttgata acgatcataa atatcattca tcgttattct caagcctaat ggatcaattt
    17821 gccaacccca ttcacttgct tccagatatg gatttttgac agaagcaaag atatttcctg
    17881 cagtctgttc caagagttcg ttgtcagtag tcgaaactcg agaagaataa taagaaaagg
    17941 agataaaatc aacagtatgt tctttcagca atgcggcatc cccaggttcc attttgatct
    18001 gaatgccatt tcgttccatt tctttcaatg cataagcagg atattctcct cgtgactgga
    18061 catcaatgaa gaaataattt tctcgatctg attttctaga agcccaaaca tcttcaggat
    18121 tgcaagtgta tggataatat gctcctgctg ccagcataca gcctactttg ttctccggat
    18181 ctacttcatg agcaatcttc gttgcgatgg cacttgcaac caactcatga tgtgccgctt
    18241 gatatttgat ttgttcttca ttttctcctt cttcaaaata cagccctgcg cccatgaatg
    18301 gtgcatgaag gatcatattg atctcattga atgtcaacca atatttgaca agtcctttat
    18361 agcgattgaa gatgactcgg cacagatttt cataaaaacc aacgagttct ctggaacgcc
    18421 acgcaccata ttctttgatc aaatgcatcg gacaatcaaa atgtgtaatc gtcacaagcg
    18481 gctcgatccc gtacttttga cattctttaa agacatcctc ataaaatttc aaaccagatt
    18541 catttggctc tttttcatcg cccattggaa aaatacgact ccaagcaatg gacatccgat
    18601 aagtcttgaa ccccatttct gcaaataaag caatatcttc cttataatga tgatacatat
    18661 cgatcgcaat ttttgctgga taaaaatgat tttcatcaaa ttcaaacatt ttcttttttc
    18721 cagtaatgac aggaaaacgg tcttctccga ttggcacaac atctacgttc gctaacccac
    18781 gtccgccttc atcataaccg ccctcgcatt gattggctgc tgtagctccg ccccataaaa
    18841 aatcttttct gaatcccatc atacttcctc cattacatgt gtattgcttg ataattctct
    18901 tgccagttca tcttggactt cgattccttc tgcttttaac cggctgattg tttccttgaa
    18961 ttgcggtaaa tactgctgat gtgcaataaa caactcattc atgatccgtt ttgctgtctt
    19021 tcctgatcgt ataagcggat tgatcgtaaa cgcttgtaaa gctgttccat aatcaccagt
    19081 cacagctgct tcgatcgtca gcaattccat attcttcatt acttgcaacc agcctctttc
    19141 agcagcagga agggaaccaa acgctacatt tcgtgcgcct tgtgcgccaa cataggcagt
    19201 gacttctact acacaatctg ccggcagatc aggaacagct ccatcattct ttgtagatac
    19261 cacgatctgt gtttctttat ttccatagat cgaagcaatc gtttcacagg cagcatctga
    19321 ataataagca ccacctcgtt tttgcaattg ttcaggttta tgatccaatt ctggatcttt
    19381 gtataattca aacagctctg cttctgtttc tttcacttgc tgcgctcttg taccaatcgt
    19441 ttgatattct tctaaagcat gttccagcat ttcttcttca cggtagtaat agcggtggta
    19501 gccacaaggg atcatgttca tttgttttaa ttgttctttg aaaaacggga tatcaaagat
    19561 atttttcggc aatccattgt cttcatcgta taaacgatca atcaattctg ccgtgcggtc
    19621 atttccttta ttatctgcta ctttgtgcca atggaagtga tttagaccgg caaacttgta
    19681 gatcagctct tcttttttct tgccaagcat tgttggttct gtcatcatcg ccattactgg
    19741 cacattgcat aatcctatca ctttatccca tttgccatat ctgataactg cttctgtcac
    19801 catcccgctt gggttcgcga aattgatcag ccaagcattt ggacataaac gcttcatgtc
    19861 ttcaacgatt gccaaaacca ctggaacggt acgaaaagct ttgaatatcc cgccagcacc
    19921 atttgtttct tgcccaatca tcccataata actagggatc cgctcgtctt tgattcgtgc
    19981 atctaattga ccgacacgaa actgagtcgt aacaaaatcc gcatctttca atgcttcttc
    20041 ccgatccaga gttgcataga ttttgacttc atacggagaa gcatcccaca tacgctgaga
    20101 catctgactg acgatctcaa gcttttcttt tccttcttct acatctacga gccagatttc
    20161 tcgtatcggt aattcctcat atcttttgat aaatccttcc atcaactcgg gggtgtaact
    20221 gctgcctcca ccaatcgtag cgattttgat tccttttgcc atgttctcac tcctttactt
    20281 tttacacttt tattatcttt tttgtaaaca aaacaaacaa tagaaattcg tttctttcca
    20341 gtaacattta caaaagttag tgttttctac tggatttttg taaatatctt gtcaaaaaat
    20401 gtctttatta agctatataa cataaatccg tttacaaatc attttcaaaa aagttataat
    20461 ttacgtaaaa aaacaagaag aaggtatcta catgttatta cgtgaaaaaa tcaaagaaat
    20521 ctccttttct ccttcagaaa atgaagtgat tcagtttctc ttaagcgatt ctccagcact
    20581 tggcgaaatg accatccaag agattgctga gcgatgttat gtccacccgt ccacactcat
    20641 ccgtgtagca aaaaaaatgg gttttgatgg ctgggtcagt tttcgtaatg cttttttagc
    20701 tgaaacagcc tatcttgaag ggaattttca agacgtagat gcgaatcttc ctttttccac
    20761 cacagacggt attatgacga tcgcaaataa aatggcttct ttagaacaga tgacgattca
    20821 agatacactt tctctcattc atcatgacca actgcaaaaa gccaaacaac taatgcttca
    20881 agcaaaaaaa atcgtgattt tcgccagtaa ctcgaatact ttgatttctc aagatttcat
    20941 gctgaaaatg aagcgcatca aaatggatgt cacgattgtc accacttttg gtgaatcgtt
    21001 ctatgaagcg tacaattgca cgagtgatat gtgcgggatt ctgatttctt atacgggtga
    21061 aaacaatgtg atccttcgta ccgcagaaat attgaaacaa aatcatgttc caattttagc
    21121 tttgaccagt atcggtgatt caacgctatc ttcaatgagt acagccgctt tgcgacttac
    21181 gacacgcgaa cgactgtatt cgaaaattgg taattttacg atcaatacat cgatttgtta
    21241 tcttctagac gtgttatata gttgtgtttt tgcagaaaat tatcaacaga atttagtcca
    21301 tctaatttct gtaggacaaa aatttgataa acgccctatc agctcagcca tcatgaaaga
    21361 gcctttcaat tttgaaaata aagaagtgga ctaaaaagaa taattaagcc tagtccattc
    21421 tttcacctaa ccgttcaggt cagtgcggtg ataagtgcat cgtctggccc gaccgtctcc
    21481 ccttgatttt ccaaaatatc caaataatcc gtgtaattgg tgacgatcac aggtgtttct
    21541 aaactgtatc cttcctcttc gattttcttt ttgtcgaagc ggagcaacag atcgccttgt
    21601 ttcactcttt ctccttgctg caccaagctt tcaaaatatt tcccttccaa ctgaacagta
    21661 tccaatccga catgaatcag caattccaga cctgcttcag aaaccattcc gattgcatgt
    21721 ttcgtcggga acagggtcat gactgttccg tcaaaagggg cacgtacttc tcctttttca
    21781 gggtagatca agattcctcg acctagtgtt ccttgtgcaa aagctgcatc ctttgctgca
    21841 ttcagtggag cgatttgtcc ttgtatcggt gtttttacaa tttctttacc tgatcttttc
    21901 tgtctatcat ctgtttcacc tgcttcctcc ttccaaaaga aaaaagtcag cgcaaaggat
    21961 accaccatcg caatggcgat tccaatcaat acattaatca catccgttaa atcaccatct
    22021 ggtctaatat agttgggaat tgtaaagatg cctaatccac ctggattcca agaagttaaa
    22081 ttcattaatc cactatacgc gccccctaac gcaccaccga cacaggtaaa aataaatatt
    22141 tttttacgtg gcaatgtaaa cccataaata gctggctctg taatccccac aataccagaa
    22201 acaatggctg gtattgcgat tgctttgtct tttgggtttc taagcttaaa gtagagtgca
    22261 gtaagtgctg cagtttgtcc aaaagacact actgcaacag gtgtcatgat attttgccaa
    22321 ccattcacag aaaattgcat caatcccatt ggtacgattg cccaatggag accaaacatc
    22381 actagaattt gccagaagaa gcctacgatt gctccataaa taactggcga aagtgctaaa
    22441 agtgtttcaa atccagccat taaaatatca gttgcgaatg tgaatgctgg tccaacgagt
    22501 aaaaaaccta agggcattgt aataagaacg gtgaagaatg gaacgaagaa attcgcgatc
    22561 atctcaggta ctaacttttt aattggtttc tgaatttggc tagctaacaa cacaataaag
    22621 ataatgggaa tgacagaaga agcgtagtta cgcgcaatcc agggaatgcc gaatactgtt
    22681 tgataaatag gtgcttcaaa aatagtgcca gaaaatatgg tagtcagtgg tgcttctgct
    22741 gcaccactca aagcttccag cgacaagcta ggattcatta atgctgcccc aagcaacatc
    22801 cctacgaatt catttacttt aaatttacgg gcagctgtta aaccgataat aacaggcata
    22861 aattggaata cagaatcacc gatattatca aacataacaa atgtgccaga accgcggtca
    22921 aatgcgccta agaagacaag taatgctgtc agtccacgaa tcatcccacc agcagctaga
    22981 atagcaagga atggctggaa acagcccgat attccatcaa taagcatatc aaacggtctc
    23041 attttttctg ttgaaacagc ctcatcaaaa gtaaggtttc ctgcttttat aacctcttca
    23101 aacacgactg gcacatgatt cccgatgaca acttggtact gtcctcccgc tcgcattacc
    23161 gtcacaacac cgtccatatt tttcaagatc tcatcatttg ctttttcttc gttttttaat
    23221 ttgaaacgaa gccttgtgat acaatgtgtc aaaccattga tattttcctt cccgccgaca
    23281 ttttctacaa ttttgctcgc taattcttga tattttccca tttctattcc ctccaattta
    23341 ttagtggaag gtttagccaa ctgaatgtca ctacccttat ttcatgcgtt cttgttaatt
    23401 tatcctcctt tttttattta tttacaacga ttctcatgca ctaaacgcgc aatatggatc
    23461 gttaaataca ttttttcgtc cgtggacatc tggtagttga atatctcggc taaaaagtct
    23521 gctattttct caacgcaacc aaacgtatcc ttatattttt tttgaataac ctggtacaat
    23581 tcctcagaaa cttctcccac ttctgatttt tctccatcta ggacgcgtgt cagaaaaaaa
    23641 cgtaggtgtg tgacgaatcg aaaaaaatgg actgaatctt catcaaatgt aatcttatag
    23701 taatagcgga cgatatttag aatatcctgt attgttgtag taaacaggta ggtattgtct
    23761 tgttggcttt gaatgccttg tgcattgact aaatgcaatg cgataaatcc ggcttcatct
    23821 tctgataact tgatgtggta tttatccgag attttcttca ctgttttttt cccgatggca
    23881 tactctttag gaaatagttg tttgatatca tacagcaata catttggtac aaatattccc
    23941 attttgtgac gttcgatagc cgtatacaaa tgatccgtca atgcaatata caccgaatca
    24001 ttcaactgga cttgtagagc ctcttttgta tattcaatga tttcacaaga aatttctaag
    24061 tactcaagag gaatcgcttg tgccaattct tggaactgtt gtgaaagtcc gtcatttgtc
    24121 aactgaaatt ttttgtcgat gcatgagtca aaaatcgggt cacccacttt ctttttgaat
    24181 gccaaacctt ttcccatcac gatcatttcc tgatttcttt catccctggt tattacgacg
    24241 ttgttattca gtactttctc aatcagcatg ttttactcct ttccatgata tatagggctg
    24301 tatccaaaac aaaaagaaaa acccaaaaag ccgtccatgg aaccatggga gactcatcag
    24361 gtttagcttg catcaggcaa tcactatcca agttgtatcg ttttctttat attatcgaaa
    24421 gcaagcactt ttgtcaacgc tttcttagcg gctattgggc acttctgact agctgtcgtg
    24481 atttttttta aatctggtaa ttacgacact aacgctcaca gatgaagaat ctgggaagct
    24541 ctgttttatt ttcactctag cgcttaggtc aaaatgctac tatgctactg tcccaacttc
    24601 taatatacgg tgttccagta ccagcttatc ggtgataagc caaatttatg caaaaatctg
    24661 gaaagccttt tttacaattt ttttcttatc acctaaagct gaacggagcc ctgtcacaac
    24721 cactttttac acaccactgc tttgcagttt gtacatatct gcatacaaac cattttgcgc
    24781 tagaagtgtt tcatgattcc cacgttctac tatatgacct ttgtctaaaa ctaaaatcaa
    24841 ttctgcatcc cgaatcgtgg acagccgatg ggcaatcgca atcgttgtcc gtccttgtcg
    24901 catttttgtc aatccttctt ggatcaatcc ttctgtttca gtatcgatat ttgctgtcgc
    24961 ttcatccaat actagtattt taggatctgt cacgattgtt cgcgcaaaag tgatcagctg
    25021 tcgttgtccg ctagaatagc tggcaccgtg ttcgatcact tttgagtgat atccttttgg
    25081 taattcatcg atgaacttgt ttgcttgaac aaactcagct gcatggcgaa tctgttcgtc
    25141 tgtgatagtt ggattcatca tccggatatt tcctgcgata tctccataaa acaagaaggc
    25201 atcttgcaag accaatccca ttttcttacg taactcttcc attggatatt ctcgaatgtc
    25261 atgatcatca atcaagatct ggccttcata aaattcgtaa aaccgcatca atacgttgat
    25321 gatcgagctt tttccgcttc cggtgtgccc cactaatgca acggtctctc ccggattagc
    25381 gacaaaagag atattgttca atacattgtg ctctccatca taagaaaagc ttacattgcg
    25441 aaactcgatc ttacctgaag taatcgcttg atctgctcca ggattttgtt gcggtgcata
    25501 ttcttctgta tccatgattt tcaaaatacg actaccggca accattccat ctgtaaaggt
    25561 gctcaaaaag tccatcattt gagacattgg attaaaaaat ccctggacat aggtcgtaaa
    25621 tgcatagatc agtccaactt ctacgggaga atgcagcgca tcgatcccaa acaaagtcaa
    25681 cgccaacgca atcgccaatg catatagaaa attgatgatc ggacttaaca gaatcgaatt
    25741 tgttttgatc atcgcatagc gcgtgtctaa atactcgttg ttcacttgtt caaattcttt
    25801 agctaaacga gcttcttggc gaaactgctg gataatacgc atgccggaaa tcgattcatt
    25861 caatttcgtg ttcagctgac ttaatttttc ccgcatattc cggtaaatac gagaactgaa
    25921 tttctggtaa taccagatga cgattcctaa aatcggcaag aacaccaaag tccacaaggc
    25981 aatttctcca ttgatttgaa acatggcaat gaaggaagaa acgactgcaa agatcccagt
    26041 caataccatc aaaaagacat accaaaattc aaatagcgtt tctgtgtcat ttgtcactcg
    26101 agaaacagtc gatcctgccg gtgtctgatc aaaataacgc atacctagtg tatgcagctt
    26161 ttcaaataat cttacccgaa catactgata ggtcttcaat gaagccatgg aatacaaata
    26221 ccattggaaa aaccaaatga tacttttgac tatgactcca aacaagtaca taccagcaaa
    26281 aaacaaaata acttgtgtcg tagccgactg tttagccaga tgatcatcca taaaagtttg
    26341 gatgatcctt ggcaatagga cattgatcac agacagggca aacgcaaata agatagcaac
    26401 gatgaacgtt cttctaaaag gtttggcgaa cttcatcagt cgtttgatga tcttcttctg
    26461 ttctttaagt ggaatcgatt ttgtccattc cgattgataa ttttcatcca tcaggcctcg
    26521 cctccttcta tcttcgcttc taatttctgt ttctcccaca ttcgttcata ccagccgcct
    26581 aatgcaagca gctcatgatg ggttcctcgt tcaatgattt tcccttgatc gacaacaatg
    26641 atttcttttg catgcatcac gctgcttaaa cggtgagctg caatgatggt tgttttctct
    26701 tttcttattt cttttaaatt atgcaagata gcttcttctg ttttggcatc tactgcagaa
    26761 agtgcatcat ctaagatcag caattcagga tttttgatca atgctcgagc aatcgaaatc
    26821 ctttgtttct gtccgccaga taaagagact ccacgttctc caactaaggt atcataacct
    26881 tttggtaatt ccttgatttc attgttgata aatgctaaag aagccgcatg ctctacttct
    26941 tcttctgaaa gttttggatt agaaaaacgg atattatctc gaatggtcat cgaaaacaag
    27001 aagtgatctt gaggcacata gccgattgat cctaataaag cattcaatga atattctttg
    27061 atcgaacatc cgccaaattg aatttttcct tgataatcat cgtattcacg catcagtaat
    27121 ttgatgattg tcgtttttcc cgcaccagtt ttcccaacaa tacctaatgt ttctccttct
    27181 tggatcgcaa atttgatttg ttctaatgct ggtgattctt ctttcggata gttaaaagag
    27241 gaaatagcta cattcagctc gccttttgcc ggagtctgca ctgcacccag ttgttccacg
    27301 atatgcgtct tttcatgcaa aagttcattg acgcgatcat aagaagcatt tcctctttcc
    27361 aatacgttga acaatcgacc aatcgcaaac atcggccaaa caagcatacc gatatagcta
    27421 ataaatgaga ccatctgccc gattgagatc gtgccttcca agacatactt tccacctaaa
    27481 ataattgttg caacataaga cagaccgata atcaaggtaa tgaatggatc aaataaggag
    27541 tctaaaaaat tgactcgttt gtttttaata attgcatctt caatcttttc ttcaaaatcc
    27601 gcgagatctt ctttttcttg tccaaatgtt ttaatgactt tgatcccagt aatactttct
    27661 tgtgtcttat cattgatact agaaaaagct tcttgcgaat cacgaaaagc atcgtggagt
    27721 tttgacccca gcactcgtga agtaacggct agtaaaggca gaggaatcag cgcaatcagt
    27781 gttaagcgcc aatcaataaa caaaatcatc gcaatgatcg ttgttccgcc cgtgatcact
    27841 gaatctgcaa aggtcaagat accagctcct gctacatttt ggattgcatt caaatcattc
    27901 gttgcatgag ccatcaaatc tccagtccga tatttttggt aaaagagatt gtccatttct
    27961 gtaaaatgtt tgaatagctg ctgccgaagt tctttctcca accgagctgc acttccccaa
    28021 atattcgtcc gccagatata acgaaaaaga tattgtaaga gagctgcaag gatcaataat
    28081 aagatccacc aggaaatgat ctttattgat aaatttttat cggcgatctc atcaatgatg
    28141 atcccaatca cttttggagg agctaactgt accaaggcca ctgcgaatag ggagaaaatc
    28201 ccaattaaat aatgtttctt ttcctgtcga aaaaaccaac ctaattttct aaaaatcgac
    28261 attttactcc tcctttgtct ttatcaagag cataggattg tctgtgcttg tcttttttgc
    28321 tgaatagtct gaatagtcta acaaattacg aaataaaaaa cggactgaaa aaatcagccc
    28381 gcaaaaagtc tttgggtcag aacctatttt ttcccttggt tcttcatttg ctgcatcatc
    28441 tggcgaattt tcttctcaga tggtttttgc cccattgaca tcatcattga tcgcaacatg
    28501 tcctcattaa cgggaggatt tttttctaaa tagtctttca tatatttacg cgctaggaaa
    28561 aagccaccta ctgcgccgat tagcaaagca ataatagcaa taagtacgac aatacctgtt
    28621 gataccatat aaatctctcc tttctatttc cgaattgctc tcaatgattt attttactaa
    28681 agtttattga aaaaagaaag gcgtattctt tagtttcatg caaaaaatag tggttttttt
    28741 agagaagaac aaaatttctt tcattaacca gcaagacacg ccacgaaaaa aaattaggca
    28801 taccaaatct ttttctttaa ttttttcttt ctgaggtgta gaatgtaatc gtagataaat
    28861 aggaaaggtg gttttttctt gaataatcaa tccaacaaac aatttcataa gcatcgactt
    28921 attgaacata caaatggttt atctttagct gaagtaaatg gaacagtgga tgtacccaag
    28981 ggaaaaagtt tttttaaaac acttcttgct tactctggac caggtgcatt agtagcagtt
    29041 ggttatatgg atccaggtaa ctggtccact tcgatcactg gtggacaaaa tttccaatat
    29101 ttattgatgt cagttatttt gatgtctagt ctgattgcta tgcttttaca atatatggca
    29161 gcaaaattag gaatcgtgac ccaaatggat ttggcccaag caatccgagc acggacaagt
    29221 aagacattgg gtgtcatttt atggatcttg actgaattag ccattatggc aacagacatc
    29281 gcagaagtca ttggtgcagc aatcgccctc tacctgcttt ttgatattcc attggtaatt
    29341 gccgtattta tcactgtgtt agatgttttc gtccttttat tgctgacaaa agtcgggttt
    29401 cgtaaaatcg aagctttggt tgtctgcttg attttcgtca ttttattcgt tttcgtctat
    29461 caagttggct tgtctaaccc tgattggcac agtttgtttg ccggatttat ccctaacagt
    29521 cacacattct cagactcacc ggtcatcggc ggcgaaactc cgctgactgg agctttaggg
    29581 attattggtg caacagtcat gccgcataac ttatatcttc attcagcagt ttctcaaact
    29641 cggaagatcg atcaccaaga cgaagaagat gtagcacaag cggtacgctt ttctacttgg
    29701 gattctaata tccagttgtc aatggctttt ctagtcaatg cactgctatt gatcatgggt
    29761 gtggctgtat tcaaaaccgg ttctgtccaa gatccttcct tttttggtct gtatgaagct
    29821 ttatctgatc catcagctat gagcaatggt atcttgattg ctgtagcaaa atctggtatc
    29881 ttgtctactt tatttgctgt agcacttctt gcttctggcc agaactctac tattactggt
    29941 acgttgaccg gtcaagtcat catggaaggc ttcatccata tgcgtatccc aatttggcta
    30001 agaagactag tcacacgatt gctttctgtg attcctgtat tgatttgtgt tttgtttaca
    30061 agtacaaaag gaacgatcga agaacatacc gctttgaata acttgatgaa tgaatcccaa
    30121 gtttttctgg cttttgcatt gccattctcg atgattcctt tactgatgat gaccaatagc
    30181 caagcggaga tggggagccg attcaaaaat tcatttgttg taaaactact tggctggttc
    30241 tctgtgatta gtctgactta cttgaattta cgaggattac caggtcaaat cgaaagtttc
    30301 ttcggcgagc aagccacctc agctcaacta gcattggctg atcaaatcgc ttatgtaatc
    30361 attgttcttg tccttctcct gttggcatgg acgattggtg atttatataa aggaaacaaa
    30421 aaatatgaac agcgtttgca ggaaacgata gaagaaatcg agtagaaact gattctttta
    30481 cacaaaggag gttgtgtcag aagtgggcag cttcaagaaa taagaaggaa tttaagaaaa
    30541 ttgcttttca aatttttgtg aaatttcggc ttatttccga agaagttact tctggaacac
    30601 cgtgtatcag aggttgtgaa aaagctgcct tgcatcaagt aataagaaca gccaagtaaa
    30661 aacagctttt tatgttttta acttggttgg acttattacc gcagatgcaa gcttttgagc
    30721 accgtttatt cggaaaaagg aactgcgaca agacttttgt cacagttccc tttcctacga
    30781 ttagtcaagt aaaaggtgta agaaaaatag ctcataaacg aaagcgacaa aatcaaggca
    30841 caccaaataa agccccgttc gtaaaaaatt ttcgatctgg gcaaagaagt ggtatactgt
    30901 aagtggttta gttaatggtc cactgagacc gcgtacgcat agtcgtactc tgtatgtgcc
    30961 ctaaccatag cgtgcataca tttcagaagc ttgttcatac aagcaactgt ggcaacctta
    31021 tctttcttag ggataggttg cttttttaat ttgtagtaat aatcgacaat atgattagga
    31081 gctgcgcgtt gctggcgaat catatttcga atggtgaaga aaataatttt ccgtgctttg
    31141 ggattaccac gcttattgat gcggtcttgg ccagtatact tacctgaatg ataccgtcgg
    31201 atgtcgattc cgacaaaggc attcaattgt ttatgggttt taaatcgtgt gatatctcct
    31261 aattcaccga gcaataaagc ggctgtgagt gcgccaatcc cagggaacgt ttggtacaac
    31321 aaaaagcaag gagagccttc ggcttttttg atcatttgtg tcgccagtgc ttctttttgt
    31381 tcgagtaaat cttggagaag ttcagcgtaa tagatcgttt tttgacagtg gatactgtct
    31441 ttttcaacag ctggataggc acactgtgca tagtggatga tttgatctgc cttttgctcg
    31501 gcacgattcg cggagatttt tttccgtgtt tcgttgatca gtttattttt tatttttgtc
    31561 cgagtagatg ccaatacaaa atctggatgg ggaaaaagac ggatcaatat caatgcgtaa
    31621 ggggtcagcc tgtttaaaaa gaactgttca agctctggaa aagtcaactg aaggcagttg
    31681 tgtaaatcca tgcgcagacg agtgattttc ttctcaattt cttgataaaa acgggctaaa
    31741 tcgcgcatct ctaagtaaaa attgctttgt acttcttttg gctgacgttg atttttaaga
    31801 tgagtctgtg cgagccgatg ggcatccgat ttatctgttt tccaactgca taaggtgttt
    31861 tcttccatct gttttttcgc ttctaacggg tttaacaaac agtaagaaaa gtgatgatct
    31921 tgaaagaact tttcgactgg tctggaataa atccccgttg cttcaaaaac aatcaatgga
    31981 cgttcaggca agtgctggat ctcttcgagt aatgcatgaa atcctctttg agtgtgttcg
    32041 atctcgtctt caaataagca ggtgtcgtct ttgtatagga cactgtagct gtgtcccatt
    32101 gaaacatcta atgcaagaat gtaaggcatt tgttttcctc ctttttaagt tttgaaagaa
    32161 ctttactgct tcatttcgat tccaatttcc tatacacggg ctcatggccc caacatacgt
    32221 aaacctgatt ctaaaatgac agtaaagaag ttcggttttt gatagggact catagtcctc
    32281 aaggctttgt tcgaactttc tttcactctt cactataatc taaaaataga aaatagagga
    32341 gaacatcatt cgtcaatgat gttctcctct aatcttagta tgtttttatt tggaagataa
    32401 agcttttttc agattcaatt tactgaaaac tagcatgctt gttactacga tgaattgcgt
    32461 taatggcacg cctgcgccag tgtagacact taaaaaataa tccttttttt ctggcgcata
    32521 agaacaaaac cacgagacgc cgaaaagaaa aaccaattgt gtcagtatta atccggtgac
    32581 tacaatcaaa gaggaactat aataggcacg atcagctttt gcaaatgcgg ttcctagtat
    32641 cataagtaat atccctgcta ttgaagcaat cagcacggga atggccagaa cttggtaaat
    32701 ttttatcatg acattcgcga cttttgctgt ttttgtcaac tggaaatcag gtgttctcgg
    32761 atcactgcta tcgatccaat tatccattag tggaagattc aataattctt gggcctgttc
    32821 gacttgttct tgcgtaccga aactataatt ccccccttga tggaaatctt tgtatcgcca
    32881 tgcataggca tatcctgatt tcagaaaagc aaatacgatt ggcagatcat tcatcgtctt
    32941 tccatcccct gatcccatca gatagaattc ttttttcttt ttgatagttc ccttttgata
    33001 ggcttcttct aattcttgat tgactttttt ccaaaaatca ttggtttctt ttgcattgtt
    33061 ttggtaataa ccagattcgc ttaccacatc tcgcaatgcc caaaaaatga tatctcctgg
    33121 taattctttt acttttccac cttgggtcca cgcatgagtc gtatacaatt cgtcaatacg
    33181 agtagaaaca gcatgaaatg taggagatgc gtctaatgct ttatttaatg cagcatgcga
    33241 gacccatatc tcactgtttt ctttatttaa gttcgtttcg tcatctattc ggatcagctg
    33301 tttcatcaaa cgtccaaatt cgccactcga acggtcattg atggcggcaa tactatatgt
    33361 tgtctcgttt ttatattcga tccactgata gacgatggag aaaccgacta gagggagtaa
    33421 aaacaatgaa agtttcagcc attcttgttt cgaaaggaga aatggtcgtt cttttaactt
    33481 ctttgcttct ttgaaagaaa agtcttgtcc tagcaagatc tggacgaaac tgatgcctaa
    33541 cgcgactaca gtaaaaggaa gaagccagat ggaatcttcg cgaatgaacc aaaagaaagg
    33601 aaaagaaaca gctagcccta aaaaccacgg cagcattttt ttgctggaac tatatttacg
    33661 gtaataaata gctagtaaac aagcgataat gatctcaaca gccggaatca cgagggcatt
    33721 acgatacgtt cgagtggaat attcatgtgt aaaactaatc ggagaaaaca aaaaataaaa
    33781 atagaaactt aaaagaagat acttgttctt cacgatcggt ttaaacgcga gtgcaaccaa
    33841 tatactggca aaaatactga acatgccgaa caaaactgca taagaaagat gcagtttatg
    33901 tgcaagtact aaaaataagc tgtaggagat tcctttggaa agtgttgtag tcgtatactc
    33961 ccctagccat ttaccgtcca aaatattttg agcatagcga atcagcagct ggtcatcata
    34021 ggttgccgac atgtctgttc catagattgc tttactatat aaatacaaac gaataattgt
    34081 aaataatagg gctatgccaa gaataaagta tgtatgtttc ttttttagtt ggttgatcaa
    34141 gggttttaaa gtgttcagca tcttttcgtc cttccaatca cgttttgcca cttgcttgtg
    34201 aaacttttcg tttttttact tttctaccag tataccctgt ttgtctaaat ttaaaaagag
    34261 gggggagaag atgcatgatg aaaaagactg caaaaagcac tcctttgttt cttaaacaaa
    34321 aaaggacaag gcaatgtgcc tggtcctttt ttgctgctgt cagatagaaa atcttagagt
    34381 atcacttctt ctgctaataa ctcaggaaac acttctggat cgaatatttg tgctttgaac
    34441 atggcgattt cttttccata tggtgcgtaa gctttctttt tatctttgcc gacataggga
    34501 gtttccaaga ttttcgaaat attgtcaaac attggatcat ggacgatctt attcagcgtg
    34561 tcgaatccga ttgttccaaa accaatattg gcgtgccggt ctttatgcga accttgcgga
    34621 tttttagaat cattgatatg gagtacttta agccgatcta acccgatgat cttatcaaac
    34681 tcttccatta cacctgaaaa gtcttcttta atattataac cggcatcatt cgtatgacag
    34741 gtgtcaaaag taacggataa tttttcattc aattttactc catcgatgat ttgcgctaat
    34801 tcctcaaatg ttcgaccgat ttccgtacct ttacctgcca ttgtctccaa agcgatttgt
    34861 gccgtctgtt cttttgtcaa aacttcattc aagccttcaa taattctagc aattccggct
    34921 tctgttcctg cccctacatg agcacctggg tgaagtgtaa tttgagtagc gcctaaagct
    34981 tccgcacgaa caatctcttc tctcagaaat tggacggcaa aaggaaacat ttctggtttg
    35041 atcgtattcc ccaaattaat gatataaggg gcatgaacga cgatatttgt tagaccgttt
    35101 tctgccatgt acgcttttcc ggcatcaata ttcatctctt cgatggcttt tcttctagtg
    35161 ttttgagggg cgcctgtata gatcataaaa gtcgaagatc cataactggc tgcttcttct
    35221 gctgctccta acagcatttt ctttccgctc atgctgacgt gtgagcctaa taacatggat
    35281 ggattcctcc ttgaaaggca attgttacta acaattccta tatattggta agatgatata
    35341 caaagaaaat gattgatttt tctttgccct gttctccata gtaactgaaa ttttctctaa
    35401 agaaaagctt aagaactctt ttataaaaaa gatcattttc tcacgtttta actcttttaa
    35461 aaaagaaatt cctgccaaaa acagccttgt ctgttttttt gttctattat ttgctataat
    35521 tagcgaaata aaaccattag ttgaggtgac ccttttgcca cgcaaaaata ctcgaaaaaa
    35581 acagaataga agaaaaaaag aaaaatggtt tgttcctaag attattttta gagtttttca
    35641 atcattgact gtttttatta ctgttcttct tttgatgttc gcagctctag gtattggaat
    35701 aggcgctggc tattttgcct atctcgtcga agacacacaa ttgccgacta aaaaagcact
    35761 gcagacagaa ctaggaaaca ttacagaaac gtcaaagatt gtttatgcag ataatacaga
    35821 gatatcaaaa atccagacag atctgatgcg cacgactatt tcatctgata aaatttcacc
    35881 tttattgaaa actgcaatta tcagcacaga ggatgaatac ttcgataaac accaaggtta
    35941 cgttcctaaa gctgttttac gagcattagt atctgaagct actggtattg gctcttctgg
    36001 tggatcaact ttgacacagc aattagtcaa acagcagatc cttacagatg aaacaacatt
    36061 caaacgtaaa gcaaacgaga tcattctttc tgcacaagta gaaaaatact tttcaaaaga
    36121 tgagatcatt gctacgtatt tgaatgtctc accatttggt cgtaataata agggacaaaa
    36181 cattgctgga gtccaggaag ctgcaagagg aatctttggt gtagatgcaa aagatgtgac
    36241 gctgccgcaa gctgcttata tcgctggatt accccaaagc ccgatcacgt atagtccata
    36301 cacgaacaca ggtgcgctaa aagaagatct ttctgccggc cttgccagaa aagattttgt
    36361 tttattcagt atgtatcgtg aaggccaaat tacgaaagaa caatacgaag aagcaaaagc
    36421 ctatgacctt acaaaagact ttctaccaca acaaatcgca gaacagactg acagagaatt
    36481 cttgtattat actgtgatga atgaagcaac aagaatcatt gcacaacaat tggctgaaaa
    36541 agacaacgct gatatgtctg attcatcggt cagtgacgct tattatcaaa aggcacagca
    36601 aacgatccaa aataaaggat atacaatcca ttcgacaatc gataaagatg tctatgctgc
    36661 attgcaaaat ggcgtagaaa attatggata catgttagat gatggtgctg gcagtcaagt
    36721 agaaaccgga aatgtattga tggataacag aactggccgc atctacggat tcgttggcgg
    36781 acggaattac agtcagaatc aaaataacca tgccttcgat acagaacgtc aagctggctc
    36841 atcaatcaaa ccagttcttg tttatggacc tgcaatcgac atggggctta tcggatcaga
    36901 atcccgtgta tcagattatg caacaacttg gcaagaagga gaaaatgctg gcgagaaaat
    36961 cgtcaatgct actaacgaag gatcgaacac cttccaaacc gtccgtgagt cactagaatg
    37021 gtccaacaat atcccggctt atcacttata tcaagatgtg ttgaattccg gtggatcgaa
    37081 acaatatgct tacgagcact acttggcaaa gatgaactac ccggcaaatg acaattgggg
    37141 cgttgaatct gctcctttag gtacagtaga tgtcacgacg cttcaacaga ccaatggatt
    37201 tcaggcttta gcaaacggcg gcgtctatga agaaggctat atcatcgatt ccatcacaga
    37261 taacgcagga aatgtaattt ataaacacga aagcaactct gtccggatct attcggaagc
    37321 aacggcatcg atcatgaatg acatgatgcg cagtgtgatc aatgcaaaaa tcactacacc
    37381 attcaaagat gccatctcaa gcttaaacgg aaatctagga aaagcagatt gggtcggaaa
    37441 aactggttct accaatgaat accgagattc atggctaatt gtctctactc cgtctattac
    37501 catcagtagc tgggcagggc acgatgacaa tactggaatg gacagcaaag caaggatacg
    37561 ttcggctaat tatcttgcca atctgatcaa tcaagcttac caagcaaaac ctgacatttt
    37621 tggcactgat gagaaattcg aattatcatc tgatgtgatg aagaaaaaag tatctggatt
    37681 tactggtcaa acacctggaa aagttactgt caataaaaaa tccatccaaa caccaggaaa
    37741 aacagttgaa tcgctatggg cgaaaaatgg accgaagaaa agcgccttta aatttggcgt
    37801 tggcggtacc gatgaaaact atacagatta ctggaacacc gcttcagctt atgcaagagc
    37861 gaatcaagca accaaagaat cagatgagaa agatgattga tttaatagaa tacacagtcc
    37921 cttatttttt tgatggtggt gaacataatg cagcatctat acacggattg ttttatatac
    37981 gataaatgta atttcaacca ctttctctct tttttaagac aaaaaaaaag gattaaacaa
    38041 aattttgtca taaccccttt tcccgaataa acggtgttct cctgccaact ccgaatcacg
    38101 agtcacaata ttcatcaaac atgaaatgct gttttttgaa attgctcctt gtaacgcaga
    38161 gttaaacggc aggctcacaa cctctgaatg gttgtccttt tattattttg tagatccttt
    38221 ttcttcgatt ccataaggca agataatcgt tttttcttcg acttcttctt tattcatcat
    38281 tttcgtcaat aggcgcatag ataccgcccc taaatcgtat aatggttgtg tgatacttgt
    38341 taaacgagga cgagctactt ctgtcagtag tgaattgtta cttgtgatga tttcgaattc
    38401 ttccggtact ttcacgccac ggtctaataa accatccaaa ataccgatgg ctaattcatc
    38461 atctgaaaca tagacagctg ttgcaccgct attatggatc cgatcgacta gagatagacc
    38521 atctttgaag ttgtattgtg cttcaaagat caatccttcg ctatatggta ggttattttc
    38581 gcttaatgct tctttatagc ctttcagacg attttgtcca ttgataggat cgatcaacgc
    38641 accactgaca aaagcgattt ttttattgcc gctttttgcc aatttgttta ctgcatcttt
    38701 tgttgctgat acataatcaa tgtttacgct acctacttgt tcatctggat caatagagcc
    38761 agctaataca acaggagttt ttgaacgtga aaattctcca cggatttcgt ctgtgatatg
    38821 gtgacccatg aagatcacgc cgtccacttg cttagccagt aagttattca atacattgac
    38881 ttctttttgg tcgttaccat ctgaatttgc taagataata ttgtatttgt acattgttgc
    38941 cacatcatcg ataccacgtg ctaaagaagc aaagaacata ttgctgacat cagggatgat
    39001 taccccaact gttgttgttt tcttacttgc caagccacgc gcaactgcgt ttggacgata
    39061 atccaagcga tcgataactt ccaagacttt ttttcttgtt gctggtttga cgtttggatt
    39121 gccatttacg acacgtgaaa cagtagccat cgaaacattt gcctctctcg ctacatcata
    39181 gatagtgatt gtttgctttt ccatttgtgt tctcctattc atattttata tgttttctga
    39241 aaatacgtct tacatttcta aaatagaata tcaaataatc tcaagaattg caaccgtttt
    39301 atctctgttt tcatgaaaat ttttactttt ttcagttttt agaacgttgg tcttttaata
    39361 aatcagtggt acaattattg aatacaaaat taatttagaa agtaggttgc caaatgaata
    39421 acgtaaaaat caatgaacta cgtcaatgga tggcacaaca ccaagtcgaa ttggcttata
    39481 tcagcgaccc tggccacatc gcttactttt ccggatacga aagtgatcct catgagcgtg
    39541 tactagctct ttttatccct cttgaacaag atcctttcct tttcactcct gctttggaag
    39601 ttgaagatgc tcaaaacagt agttgggcgt atgatgtccg tggctattta gacagcgaaa
    39661 acccttggga gatcatcgga aaagaacttc gtgctcgcta tggtcagcct ggcaatgtag
    39721 ggattgaaaa gaacgccttg actgtcgagc gcttcgatgc tatctctgat atcttgacgg
    39781 gaacggattc ttacactgat ctagcttcca tcatccaacg tctacaactg atcaaaactc
    39841 tagaggaaaa agacaaactg atcgaagctg gtaaatgggc cgatgttgca tttgagattg
    39901 gctttaaagc agtgaaagaa ggcgtgactg aacaagcgat cattgcagaa atcgaatacc
    39961 aattgaaaaa acaaggtgtt tcacaaatgt ctttcgacac attagtcctt gcaggagcaa
    40021 atgctgcaag ccctcatggt acaccaggaa acacgaagat ttcaccgaat gaacttgtgt
    40081 tattcgatct tggcgttgtt tggaatggct attgcagtga tgctactcgt acaattgctt
    40141 atcaaaaacc aaccgacttc caagaaaaaa tatacaacat cactcttgaa gcacagcttg
    40201 ccgcacaaga agccgtccgt ccaggtgtga cagcaggtga acttgatcaa atcgcacgaa
    40261 acgtgatcaa cagctatggc tacggcgaat atttcaatca ccgtttaggt cacgggatcg
    40321 gaacaaccgt ccacgaattc ccttcccttg tagaaggaaa tgacttagta atcgaagaag
    40381 ggatgtgctt ctctcttgaa ccaggaatct atattcctga aaaagtaggg gtacgtatcg
    40441 aagactgtgt atatgtgaca agcgatggct gtgtgccatt cacgactaca ccaaaagaat
    40501 tactagtttt agaaaaataa gagtaaaaaa ggtgagagct agtccgctcc caccttttta
    40561 ttctataaat ttgtgatttt agtgatttta gtgatttgta gatgaatctg tcattgtatc
    40621 ttttatttct tttttagctt ctttcgcatc ttcttttgcc attttcatca tttcttttgt
    40681 gtcatctgca actggttttg cttctgacat tccttcattg acagtatctc ctgctttacc
    40741 agcagcgtct tttacatcaa tcatgatatc ttctgaagta tctttagcaa tacttcctaa
    40801 ttcatctgca ggttttttca tatcttctgc cgtttttttg aaacgattag ataagtcagc
    40861 tgattgttct ttaagattta acaagatatc gtcagattca cttcctgctt catctgctga
    40921 ttcacttact ttttgtttga cactacctgc tagatcacct gcttgttgag aaagatcttg
    40981 cgctttttct tttgcaatac ctgttaactc agtcgatttt tctttcgcca tatctgtgta
    41041 atctgaagcc atatccatca aatcatccgc ttgggcagct aattcatccc gaagttcttt
    41101 accagatttt ggtgctaaca ataacgcggc gattgctgcg gctgttcctc cgactactgc
    41161 acctaataaa aatccacctt ttttagccat ttttattttc ctcctgtcgt ttcagtatgt
    41221 tttttgtttt taaaaaattt catcgctgtc ccaccgactt ttccggcaac cgtcgcttta
    41281 gctgtcgttt taccgattcc gccgactttc gtcgcgatgt ttttactaga atgattaagt
    41341 tctgatacac tttcacttaa atcagcaact gctgtgaaca atggatcgat cgttgcgact
    41401 tttccattga tatccaagag cagttcatta cttttgacca gcaagccttc tacttgtcta
    41461 gacaaaagat ctacgtcttt tgtgacgatt tcgatcgtcg tatttgcttc tgctacagtc
    41521 tgatctactt tttctaaagt tttagaaact tgcaacaaca cacgaacgat aaaaacgaca
    41581 agtatcgcaa aggcgattgc tgcgatcaat cctgcaattt ctcctcctga catgatcaaa
    41641 ctcccttctt gtctctcttt tctataagga tagcattttc gtgtttttta aacaaataaa
    41701 aacgagcttc aactactttt tattcaatta gcagctgaag ctcgttagaa aaaagggtta
    41761 ttttttcttt tcttctttga tttctgttat tccttttgga ttatgatcga tcttgcttcc
    41821 ttctgcttct aattttttac ctaaagacag gatatactca cgtaaaggtg cacctacttc
    41881 tggatgtgtt agaccatatt caatacttgt tttcataaaa ccaaatttgt caccgacatc
    41941 gtaacgttta cctgtgaatt tacgggcaaa tacgcgttgt gttttattca atgtatcgat
    42001 tgcgtcagtt agttggattt catttccggc tcctggttgt tgctcggaca atacatcaaa
    42061 aatttctgga gtcaataagt aacgtccaat aatagctaaa tcacttggtg ctttgcttgg
    42121 atctggtttt tcaacaaagt ttttgacatt gtataaccca tcttccaata cttctcctgg
    42181 attgataatt ccgtattttg aagtttcatc atgaggaact tgcataacgg cgatcgtaga
    42241 agcatgagta cgttcgtaat catcgattaa ttgctgtgtc aatggtactt catcttccat
    42301 gatatcatcg cctagcataa cgacaaacgg ttcatttcca ataaaggctc ttgcttgaag
    42361 aacggcatgt cctaaaccct ttggatgaga ttgacggatg aaatgcaagt tgacatctgt
    42421 cgtttcttct actaatttca ataattcggt ctttcctttt tcacttaggt ttgtttctaa
    42481 ttcaatattt gaatcaaagt gatcttcgat tggtcgttta gcttttcctg taacgatcaa
    42541 gatgtcttcg attcctgatt tcaacgcttc ttcaacgatg aactggattg ttggtttatc
    42601 aacaattggc aacatttcct ttgccatagc ttttgttgct ggtaaaaatc ttgttcctaa
    42661 tcctgccgct ggaataactg cttttttgac tttcatatac attcgctcct tcaaaaaatt
    42721 gttaatgaga attcattttc ttttttccca tcacgtaaca tgatttcttt tgcggctgtt
    42781 ttgatttctt tttgttcata cagcacttca tagattgttt gagtgatggg catttcgatt
    42841 tccattattt gggctagttc catcgctgct tgagtagtat tcacaccttc aacgaccatt
    42901 cccatattgg ctagcacctc ttctaggggc tgcccttgtc ctaacaagtt gcctgcgcgc
    42961 cagttcctag aatgaacact tgtgcaagta acgactagat cgcctactcc gcttaatccg
    43021 ataaaggtca gcgggttggc acccattgct acacctaaac ggctgatctc agctaatccg
    43081 cgcgtcatga ttgctgcctt tgcattatcg ccaaacccta agccgtgaat agcgccagca
    43141 ccaatagcaa taatattttt caaagctgcc cccatctcta caccgatcac atcaggattg
    43201 gtatagatcc gaaaataatt attcatgaac agctcttgta catattttgc tgcttttgca
    43261 tctgtacttg cagctgtgat cgtagtgatg tcatgtttcg ctacttcttc tgcatggctt
    43321 ggtccagaaa gaacaacaac agcttttctt ttttctgctg ggatttcctc taacaagatg
    43381 tcagagatcc ttttatgtgt tccctgttct aatcctttac ttgcatggat gatcactggc
    43441 tttgtattca atttaggcac tagttctttt gcaacagaac gtattgcttt cgttggaatg
    43501 acgaatagca ccgcatctgc gtcttttact gcatcttcca tattggtgaa tgcttggatg
    43561 gaatcgggta gataatgatc tggtaaataa cgttgattcg tgtgttgggt gttgatttct
    43621 tctacttgtg aagcacgatg tccccaaatc cgaacgtcat gtccgttttc ggcgaggact
    43681 tgtgccaaag cagtacccca agagcctggt cctaaaaccg ctactctata attcatttta
    43741 ccactcctga aatttttttc atttttaacg ctctaaaaat cagataattt gttgattttt
    43801 tcctaatgag cggtcataat ccggtaaatt tccttttttt ctgcgccaaa taaatagaat
    43861 caatgtaccg acaaataaca cagcagataa taattgagaa atacggatca cacctaaaaa
    43921 gtaaagactg tctgtacgta atccttcaat aaagaaacgc ccgaaactat accacattag
    43981 ataacataaa aggacttcgc cttttttcaa aaggtgtggt ttctttcgta aaaacaaaag
    44041 caaaataaat ccaatcaaac tccaaagtga ttcataaaga aatgttggtt gacgatagat
    44101 cccttcgata tacatattat caatgatgaa ttgcggtaaa tgcagacttt ctaagaagct
    44161 tcgcgtcgtg tctggtccat atgcttcgtg gttcatgaaa tttccccaac gaccgattgc
    44221 ctgtgctaat aatacacttg gtgcagcgat atctaaaaaa gtccacaaag aaataaaatg
    44281 atatttagta aaaaaataca gcgtgatcgc gcctgcaatc agtccgccat aaatagctaa
    44341 gcctcctgaa cggatattga atatttggat tggatcagct atatactggg gaagatcaaa
    44401 taaaacataa tataagcgag caccaataat ggagataggc aatccccaca acataaaatc
    44461 tgtcacatca tctgctttta atcctacccg aacagcctct ctgctgctaa gccacatggc
    44521 gataatgata cctgatacga tgatcaatgc ataccagtag ataggaatcc ctacaagctc
    44581 aaaagcaact cgattgattt gtgctaacat attgtcactc cttgctagtc gttgcctgag
    44641 ttttcttcaa tcaagcgact taatctttct tcaaatgttt tcgttgcgtc aaagcccatt
    44701 gtacgtgcac ggaaattcat cgcggctact tcaatgatga ttgcaacgtt tcgtcctgtt
    44761 ttgacaggga tttttatttg tggaatgccc acttccgcga tttcaacggt cgtgtcttca
    44821 gagcccagac ggtcgtattt cttatctttt gcccatgctt ccagataaac agccaactgg
    44881 acttgcatag agccacgtac cgcactcgca ccaaaaagat tcattacatc aatgatcccg
    44941 attcctcgga tttcaattag atgttccagg attttaggcg gttctccgat caccgttaat
    45001 tcatcttgct gataaacatc tactcgatcg tctgcgatca atcgatgacc gcgtttgatc
    45061 aactccaacg ctgtttcact ttttcctatc ccactgtcac cttgaatcag tacacctaat
    45121 ccgtaaacat ccactaaaac accgtggaca cttgttcgag gggcaaggcg accatctaaa
    45181 taactggata attctcctaa taaacgagaa gttgagatgg gagaacgcag tacagctatc
    45241 ccattttcat ttgctgcctg gatcatttct tctggagccg gtaatcctct tgaaataata
    45301 aatgcgggca tatcttcact acataatctt ctcatgatga tcaaacgctc ttctgggatc
    45361 atccgttccg caaaactgat ttctttactg ccaaatagct gtaaacgatt atgggaataa
    45421 taattaaaat aaccagtcaa ctctagtcct gggcgtgaga tgtccccagt tacgatgaca
    45481 cggtctaagc ttttctcgtc gcctgtcacg atttccaaag ataatttttt cactaattgg
    45541 ctaactttta caacttctga cattcatgct acctcatttc tattagagtg ttctctatca
    45601 ttttatcatt gtctagccaa aagtactacc aattaaaaaa aacgttttta tttaattacc
    45661 aatgtaata
//
LOCUS       DAFLWZ010000016        44969 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000016 DAFLWZ010000000
VERSION     DAFLWZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.016"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            212..604
                     /locus_tag="L1V38_000940"
     CDS             212..604
                     /locus_tag="L1V38_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1315504.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="L1V38_000941"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="L1V38_000941"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBN1315505.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="L1V38_000942"
     CDS             3165..4775
                     /locus_tag="L1V38_000942"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBN1315506.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="L1V38_000943"
     CDS             5067..5936
                     /locus_tag="L1V38_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBN1315507.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="L1V38_000944"
     CDS             6101..7372
                     /locus_tag="L1V38_000944"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1315508.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="L1V38_000945"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="L1V38_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBN1315509.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="L1V38_000946"
     CDS             8763..9026
                     /locus_tag="L1V38_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBN1315510.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="L1V38_000947"
     CDS             9471..9920
                     /locus_tag="L1V38_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1315511.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="L1V38_000948"
     CDS             9977..11395
                     /locus_tag="L1V38_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1315512.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="L1V38_000949"
                     /pseudo
     CDS             11395..12255
                     /locus_tag="L1V38_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
     gene            12429..13202
                     /locus_tag="L1V38_000950"
     CDS             12429..13202
                     /locus_tag="L1V38_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1315513.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="L1V38_000951"
     CDS             13349..13714
                     /locus_tag="L1V38_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBN1315514.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="L1V38_000952"
     CDS             complement(13862..15070)
                     /locus_tag="L1V38_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315515.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="L1V38_000953"
     CDS             complement(15089..15367)
                     /locus_tag="L1V38_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315516.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="L1V38_000954"
     CDS             15521..16216
                     /locus_tag="L1V38_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1315517.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="L1V38_000955"
     CDS             complement(16658..17455)
                     /locus_tag="L1V38_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBN1315518.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="L1V38_000956"
     CDS             complement(17452..18636)
                     /locus_tag="L1V38_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1315519.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="L1V38_000957"
     CDS             complement(18661..19908)
                     /locus_tag="L1V38_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1315520.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V38_000958"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V38_000958"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBN1315521.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="L1V38_000959"
     CDS             21888..22202
                     /locus_tag="L1V38_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBN1315522.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="L1V38_000960"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="L1V38_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBN1315523.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="L1V38_000961"
     CDS             22887..23531
                     /locus_tag="L1V38_000961"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBN1315524.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="L1V38_000962"
     CDS             23546..23875
                     /locus_tag="L1V38_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBN1315525.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="L1V38_000963"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="L1V38_000963"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBN1315526.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="L1V38_000964"
     CDS             24863..25687
                     /locus_tag="L1V38_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBN1315527.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="L1V38_000965"
     CDS             25680..26027
                     /locus_tag="L1V38_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBN1315528.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V38_000966"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V38_000966"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBN1315529.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="L1V38_000967"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="L1V38_000967"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBN1315530.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V38_000968"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V38_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBN1315531.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V38_000969"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V38_000969"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBN1315532.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="L1V38_000970"
     CDS             31657..32451
                     /locus_tag="L1V38_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315533.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="L1V38_000971"
     CDS             32441..34483
                     /locus_tag="L1V38_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315534.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="L1V38_000972"
     CDS             34764..34913
                     /locus_tag="L1V38_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBN1315535.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="L1V38_000973"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="L1V38_000973"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBN1315536.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="L1V38_000974"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="L1V38_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBN1315537.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="L1V38_000975"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="L1V38_000975"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBN1315538.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="L1V38_000976"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="L1V38_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBN1315539.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="L1V38_000977"
     CDS             39330..40412
                     /locus_tag="L1V38_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBN1315540.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="L1V38_000978"
     CDS             40412..41215
                     /locus_tag="L1V38_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1315541.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="L1V38_000979"
     CDS             41285..42025
                     /locus_tag="L1V38_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1315542.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="L1V38_000980"
     CDS             42036..43040
                     /locus_tag="L1V38_000980"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBN1315543.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="L1V38_000981"
     CDS             complement(43085..44929)
                     /locus_tag="L1V38_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315544.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14463 a         7839 c         9353 g        13314 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcatagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaac
//
LOCUS       DAFLWZ010000017        44672 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000017 DAFLWZ010000000
VERSION     DAFLWZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.017"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1008)
                     /locus_tag="L1V38_000982"
     CDS             complement(<1..1008)
                     /locus_tag="L1V38_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1315545.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="L1V38_000983"
     CDS             complement(1188..1532)
                     /locus_tag="L1V38_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1315546.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="L1V38_000984"
     CDS             complement(1525..1959)
                     /locus_tag="L1V38_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBN1315547.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="L1V38_000985"
     CDS             2097..2834
                     /locus_tag="L1V38_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315548.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="L1V38_000986"
     CDS             2827..4038
                     /locus_tag="L1V38_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315549.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="L1V38_000987"
     CDS             4242..5024
                     /locus_tag="L1V38_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBN1315550.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="L1V38_000988"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="L1V38_000988"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBN1315551.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="L1V38_000989"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="L1V38_000989"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBN1315552.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="L1V38_000990"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="L1V38_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBN1315553.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="L1V38_000991"
     CDS             8626..9675
                     /locus_tag="L1V38_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBN1315554.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="L1V38_000992"
     CDS             9672..9950
                     /locus_tag="L1V38_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBN1315555.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="L1V38_000993"
     CDS             9925..10395
                     /locus_tag="L1V38_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBN1315556.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="L1V38_000994"
     CDS             10412..10714
                     /locus_tag="L1V38_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315557.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="L1V38_000995"
     CDS             10731..11102
                     /locus_tag="L1V38_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBN1315558.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="L1V38_000996"
     CDS             11074..11433
                     /locus_tag="L1V38_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315559.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="L1V38_000997"
     CDS             11605..12612
                     /locus_tag="L1V38_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1315560.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="L1V38_000998"
     CDS             12637..13821
                     /locus_tag="L1V38_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBN1315561.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="L1V38_000999"
     CDS             complement(14258..15841)
                     /locus_tag="L1V38_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1315562.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="L1V38_001000"
     CDS             complement(16419..16562)
                     /locus_tag="L1V38_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBN1315563.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="L1V38_001001"
     CDS             complement(16785..17264)
                     /locus_tag="L1V38_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1315564.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="L1V38_001002"
     CDS             complement(17337..17621)
                     /locus_tag="L1V38_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315565.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="L1V38_001003"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="L1V38_001003"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="L1V38_001004"
     CDS             complement(17965..19251)
                     /locus_tag="L1V38_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBN1315566.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="L1V38_001005"
     CDS             19389..20060
                     /locus_tag="L1V38_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBN1315567.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="L1V38_001006"
     CDS             20026..20514
                     /locus_tag="L1V38_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBN1315568.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="L1V38_001007"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="L1V38_001007"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBN1315569.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="L1V38_001008"
     CDS             21475..22239
                     /locus_tag="L1V38_001008"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBN1315570.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="L1V38_001009"
     CDS             22472..24685
                     /locus_tag="L1V38_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBN1315571.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="L1V38_001010"
     CDS             24696..25142
                     /locus_tag="L1V38_001010"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBN1315572.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="L1V38_001011"
     CDS             25313..26572
                     /locus_tag="L1V38_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBN1315573.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="L1V38_001012"
     CDS             complement(26661..27608)
                     /locus_tag="L1V38_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1315574.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="L1V38_001013"
     CDS             28002..29294
                     /locus_tag="L1V38_001013"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBN1315575.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="L1V38_001014"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="L1V38_001014"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBN1315576.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="L1V38_001015"
     CDS             31187..32062
                     /locus_tag="L1V38_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1315577.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="L1V38_001016"
     CDS             32328..34211
                     /locus_tag="L1V38_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1315578.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="L1V38_001017"
     CDS             complement(34286..34570)
                     /locus_tag="L1V38_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1315579.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="L1V38_001018"
     CDS             complement(34560..35294)
                     /locus_tag="L1V38_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBN1315580.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="L1V38_001019"
     CDS             35423..36046
                     /locus_tag="L1V38_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBN1315581.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="L1V38_001020"
     CDS             36238..37359
                     /locus_tag="L1V38_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBN1315582.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="L1V38_001021"
     CDS             37366..40494
                     /locus_tag="L1V38_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBN1315583.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSRAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="L1V38_001022"
     CDS             40513..43707
                     /locus_tag="L1V38_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBN1315584.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="L1V38_001023"
     CDS             complement(43853..44560)
                     /locus_tag="L1V38_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1315585.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14331 a         7944 c         9384 g        13013 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaagacaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgcgc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ct
//
LOCUS       DAFLWZ010000018        37057 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000018 DAFLWZ010000000
VERSION     DAFLWZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.018"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            299..1960
                     /locus_tag="L1V38_001024"
     CDS             299..1960
                     /locus_tag="L1V38_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1315586.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="L1V38_001025"
     CDS             complement(2030..2392)
                     /locus_tag="L1V38_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBN1315587.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="L1V38_001026"
     CDS             2460..3401
                     /locus_tag="L1V38_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315588.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="L1V38_001027"
     CDS             3402..4445
                     /locus_tag="L1V38_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315589.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="L1V38_001028"
     CDS             4451..5521
                     /locus_tag="L1V38_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315590.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="L1V38_001029"
     CDS             5511..6464
                     /locus_tag="L1V38_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315591.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="L1V38_001030"
     CDS             6476..7486
                     /locus_tag="L1V38_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1315592.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="L1V38_001031"
     CDS             complement(7771..8592)
                     /locus_tag="L1V38_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1315593.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="L1V38_001032"
     CDS             complement(8689..8967)
                     /locus_tag="L1V38_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315594.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="L1V38_001033"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="L1V38_001033"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBN1315595.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="L1V38_001034"
     CDS             complement(11723..12310)
                     /locus_tag="L1V38_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315596.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="L1V38_001035"
     CDS             12485..13807
                     /locus_tag="L1V38_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1315597.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="L1V38_001036"
     CDS             13962..14738
                     /locus_tag="L1V38_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1315598.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="L1V38_001037"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="L1V38_001037"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBN1315599.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="L1V38_001038"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="L1V38_001038"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBN1315600.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="L1V38_001039"
     CDS             16628..17257
                     /locus_tag="L1V38_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315601.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="L1V38_001040"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="L1V38_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBN1315602.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="L1V38_001041"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="L1V38_001041"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBN1315603.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..19980
                     /locus_tag="L1V38_001042"
     CDS             19444..19980
                     /locus_tag="L1V38_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1315604.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="L1V38_001043"
     CDS             complement(20020..21783)
                     /locus_tag="L1V38_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315605.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="L1V38_001044"
     CDS             complement(21786..23501)
                     /locus_tag="L1V38_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315606.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24280..24504)
                     /locus_tag="L1V38_001045"
     CDS             complement(24280..24504)
                     /locus_tag="L1V38_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315607.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24695..27472
                     /locus_tag="L1V38_001046"
     CDS             24695..27472
                     /locus_tag="L1V38_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1315608.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27553..27972
                     /locus_tag="L1V38_001047"
     CDS             27553..27972
                     /locus_tag="L1V38_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBN1315609.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27984..28454
                     /locus_tag="L1V38_001048"
     CDS             27984..28454
                     /locus_tag="L1V38_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1315610.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28471..29250
                     /locus_tag="L1V38_001049"
     CDS             28471..29250
                     /locus_tag="L1V38_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1315611.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29237..30058
                     /locus_tag="L1V38_001050"
     CDS             29237..30058
                     /locus_tag="L1V38_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1315612.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30075..31124
                     /locus_tag="L1V38_001051"
     CDS             30075..31124
                     /locus_tag="L1V38_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1315613.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31137..32141
                     /locus_tag="L1V38_001052"
     CDS             31137..32141
                     /locus_tag="L1V38_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1315614.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32774..33793
                     /locus_tag="L1V38_001053"
     CDS             32774..33793
                     /locus_tag="L1V38_001053"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1315615.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33836..34717
                     /gene="galU"
                     /locus_tag="L1V38_001054"
     CDS             33836..34717
                     /gene="galU"
                     /locus_tag="L1V38_001054"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1315616.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35017..35394
                     /locus_tag="L1V38_001055"
     CDS             35017..35394
                     /locus_tag="L1V38_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315617.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36000..36614
                     /locus_tag="L1V38_001056"
     CDS             36000..36614
                     /locus_tag="L1V38_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1315618.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12132 a         6493 c         7574 g        10858 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt cattcatagg
    23701 aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata tatcaagtaa
    23761 atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa tcttttttgc
    23821 tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca aagaaggagt
    23881 atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag gaataaataa
    23941 tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac gaagacaacc
    24001 tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa aagaaaacaa
    24061 ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg
    24121 tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct gaaagcatca
    24181 taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata aggatttgta
    24241 atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat ggaaggattt
    24301 atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta tatattgcgt
    24361 atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag gcaaaaatac
    24421 aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct
    24481 gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt tcatatgttg
    24541 aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa ttataaggga
    24601 taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa gattttattg
    24661 acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga agaaggaaat
    24721 tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga acgaggtctt
    24781 tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca gtcattattt
    24841 gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag tgatttattt
    24901 ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt atttttctat
    24961 cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat tctcttttat
    25021 gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag ctctttacta
    25081 tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta aaagttattt
    25141 agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt ctgcaccatt
    25201 catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta gcaatttgtt
    25261 tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg cttttgaagc
    25321 agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag aaggtcagga
    25381 aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac ctaatttgtc
    25441 acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta gtcatttctt
    25501 aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta atcagcgtag
    25561 tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa gaaaaatggg
    25621 gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga aattatccgg
    25681 aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat atgctgaaca
    25741 gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac tacttgcgca
    25801 gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc agaccttaga
    25861 gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat
    25921 cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa aattaaagca
    25981 agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag aaaaacacga
    26041 gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg aaactgccta
    26101 tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct atcagcgaag
    26161 cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag aattagaaca
    26221 acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc tggaattaag
    26281 taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga cgatctatct
    26341 aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg
    26401 ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag aggatctatt
    26461 tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag aaatccttga
    26521 ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca tgggatctct
    26581 gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga ttttgaataa
    26641 tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg tatcattaga
    26701 agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc tctatccaga
    26761 ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta cggcggtcca
    26821 cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa tcatcccata
    26881 tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca tatacgaagt
    26941 cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc tttcattaga
    27001 agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca ctactatgaa
    27061 tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat tggaaaaagt
    27121 actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg atcattttat
    27181 gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat tagcgttgta
    27241 tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg aaacctatca
    27301 aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta aatctgcgtt
    27361 tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg cctatatcta
    27421 tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt gaacataagc
    27481 aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga
    27541 ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt tgcttcaggg
    27601 atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt attcgattgc
    27661 tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat gaggtacaaa
    27721 gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa cgaattctta
    27781 caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc actattgatt
    27841 gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca gcaggtgcta
    27901 actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa aatagaagaa
    27961 gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat cggttattac
    28021 acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt ttgattgcta
    28081 atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc aagccacaag
    28141 gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa agcggggtga
    28201 cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat aagctggcag
    28261 aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa cctggtactc
    28321 gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg aaacgattaa
    28381 ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa
    28441 gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt attaggaatt
    28501 gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc tcgtccgatt
    28561 gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat cattatgggc
    28621 gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat tccacctgat
    28681 gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc cggtacagaa
    28741 accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa aaatatttac
    28801 ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga agaaggaaat
    28861 tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt gatgcttggt
    28921 gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct attaaatatg
    28981 attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc agctcttggt
    29041 tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt tttcttaggt
    29101 tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt tggtgcgatt
    29161 ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca aacaactgca
    29221 ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa cgaaaaaaga
    29281 gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt atgaacgtca
    29341 gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat atcagtcgaa
    29401 agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga ccccacatat
    29461 cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg atgatcctga
    29521 atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc ttgcagggtt
    29581 aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg gtacctcttt
    29641 agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca atattccgca
    29701 cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg gttttttgaa
    29761 aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta ttattggact
    29821 gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt taaaaatcgg
    29881 ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc caaatatctt
    29941 atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga aaccattaac
    30001 gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga ttttttaaaa
    30061 aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag gaagtactaa
    30121 gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa acagtgaatt
    30181 tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag ccagcattgg
    30241 aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc aattatggaa
    30301 aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta
    30361 ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct atcacaaatg
    30421 acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt gccggggtag
    30481 aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta ctactcttag
    30541 ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc
    30601 aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg gaagaatttt
    30661 ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt ggatatggtc
    30721 caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt
    30781 cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca gatgcttcgc
    30841 atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa aagttgcaaa
    30901 gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa gcaagaaacg
    30961 agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta gcgcttgtcg
    31021 ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac ttgaacaaaa
    31081 agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg gaaatcatgc
    31141 tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct ttacgtccgc
    31201 aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc tattatctag
    31261 gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat gggaaaagca
    31321 acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac aaaagattaa
    31381 caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag
    31441 cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat aaagcgaaca
    31501 gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga acagaacaaa
    31561 tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc gaagcttatt
    31621 cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa gcagagaaaa
    31681 aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt atgcattatt
    31741 ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt tactgggaag
    31801 aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac gggacgttag
    31861 agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa cagagagtgt
    31921 tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca ttgatagaca
    31981 caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct
    32041 tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg aactgccatc
    32101 cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg gataaaaaga
    32161 atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa atattggcat
    32221 caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata atctgtttaa
    32281 tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag ttgttgcatg
    32341 gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc
    32401 agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa tctgtccgtt
    32461 gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta aatcaatact
    32521 cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt gtcaaaactg
    32581 cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag actattgtaa
    32641 catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa
    32701 tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca attatttatt
    32761 tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt ggggcactgc
    32821 tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa atgtacctga
    32881 acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg atttgacgat
    32941 cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg cagatgctat
    33001 tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta ttggtaaaat
    33061 gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata cgcataaacg
    33121 aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt
    33181 atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa ttacagctgc
    33241 aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg attatttcag
    33301 gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga aaaatatcat
    33361 tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa aagcagcaat
    33421 catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct
    33481 gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa gtgttcattc
    33541 tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag aagttctaga
    33601 aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag agctagctca
    33661 acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt ataatggaga
    33721 agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt
    33781 ttctcttcgt taaatagatg atcaatagtt aatcgtcgtt taggaggaac agcaagtgaa
    33841 ggtcaaaaaa gcagtcattc ctgccgctgg gctaggaaca cgttttttgc cggcaacaaa
    33901 agccatggca aaagaaatgc ttccaatcgt ggataaacca acgatccagt ttattgtgga
    33961 agaagcattg gattcgggaa tcgaagacat cttgatcgta acgggaaaag aaaaaagacc
    34021 cattgaagat cactttgatg caaatatcga attggaaaac aatttgcggg aaaaggaaaa
    34081 aacagaatta ctcgctttag ttgaagaaac gactcaagtc aatcttcact tcatccgtca
    34141 atctcatcca agaggactgg gggatgccgt gcttcaagca aaagcattta taggaaatga
    34201 accgtttgtc gtcatgctgg gggatgattt gatgaaagat gatatcccat tgactcaaca
    34261 attgatgatg gattatgaag aaacacaagc ttccgctgtt gccgtcatgc gtgtaccaga
    34321 aaatgaaaca tctaaatacg gaattattga tcctaaaaca gatagcgaaa agggtcgttg
    34381 cagagtaaaa gggtttgtag aaaaacctga aatgggaaaa gcaccaagta atttagccat
    34441 tatcggacgt tatctactga ctcctaaaat atttgagata ttagaaactc aagaaccagg
    34501 agcaggaaac gagatacagc taacggatgc acttcagact cttaaccaga cagaggcggt
    34561 ctatgcgaga gagtttaaag gaaaaagata cgacgtaggc gataagttag gatatatgaa
    34621 gacaaatatt gaatatggac ttcaacattc ggaaattggg acttcattaa gtgcatatat
    34681 tatccagttg agtaaaaagc taagaacaga aagttaactg gaaataagtg gcctgctgag
    34741 aatgaaaggc tatttgttat taaagcggca gcttgtgcgt catttgcgca actgtcgttt
    34801 tagttttttg actctagatc agttgagtcg tggaaaacga aagatagaaa aagactttcg
    34861 tgaatagatt cagaaaatat tatgctaatg gtttaatttt tttttaagtt gtataaaaga
    34921 aaatgattac ataagagaaa tgaaagccaa gccagaagat tcatagtaga ataaaaaggc
    34981 gaatttttta attataaaaa aaggtgtgtg ttcactatgg gaaaattagt cgctgttgca
    35041 cagtcgctgc ttgatatact caagtggctg atggaaggaa gcaattggat atttgtgttg
    35101 ccactattgc ttattagtct atttatcatg tttcgcatgg tcagaaaaaa agaaacgttt
    35161 ctgattttta tctggtatgc agcatccgtt ggggttgcta ccttgatggt tgaattggcg
    35221 ttaggtagtt gggaagcttg cgtatttgct ttattttttg ctgtactgta tctaatcatt
    35281 tatatcccat atatgaaaag aaagtctcgg ataggcagaa aaggtagaca tacaactact
    35341 ttttctagta cagattctct cgaacaaagt agaagaacga gaagaagacg gtaatattta
    35401 gtaggtatac gcaaaaaaag ataaaataat ggataaacta ttgagatgag agatttattt
    35461 aattggtgga aaaaagcttt tttcacttat ataaaagaat cttttttaaa ggaatgcttg
    35521 ttgtatcggg ataagccatt ccttttttta tgttatttat atatatataa atcataccaa
    35581 tgtttttttg tattttcttg cttgcacttg gataagagat tacttacaat aaattcagat
    35641 agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga atcagggaat
    35701 gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc agtgcatcga
    35761 cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat attttccatg
    35821 gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc aatgcctttt
    35881 ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt ttttatgtac
    35941 ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg gagagataaa
    36001 tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg atagaagagc
    36061 cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt ggtagattgc
    36121 agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat caaaccccgg
    36181 atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa acgctagaag
    36241 gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt tttcttcttc
    36301 tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc aaagaaaatg
    36361 gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa tcgcaacata
    36421 gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac gccaatttac
    36481 atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca gcctctcttg
    36541 caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta gtccaggaca
    36601 caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa tgttccacat
    36661 aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca acgactactt
    36721 tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt ttgtttaaag
    36781 tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga atatgtagtg
    36841 tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg attctttctt
    36901 gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa gtaattatag
    36961 tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg tccaacagga
    37021 tacctttttc taatagaaat aaaatacaca aaaattg
//
LOCUS       DAFLWZ010000019        35882 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000019 DAFLWZ010000000
VERSION     DAFLWZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.019"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1152
                     /locus_tag="L1V38_001057"
     CDS             <1..1152
                     /locus_tag="L1V38_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBN1315619.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V38_001058"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V38_001058"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBN1315620.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="L1V38_001059"
     CDS             2728..3003
                     /locus_tag="L1V38_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBN1315621.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="L1V38_001060"
     CDS             3009..3776
                     /locus_tag="L1V38_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBN1315622.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="L1V38_001061"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="L1V38_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBN1315623.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="L1V38_001062"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="L1V38_001062"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBN1315624.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="L1V38_001063"
     CDS             7920..8222
                     /locus_tag="L1V38_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBN1315625.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="L1V38_001064"
     CDS             8225..9388
                     /locus_tag="L1V38_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1315626.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="L1V38_001065"
     CDS             9414..12842
                     /locus_tag="L1V38_001065"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBN1315627.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="L1V38_001066"
     CDS             12863..13987
                     /locus_tag="L1V38_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315628.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="L1V38_001067"
     CDS             13977..14414
                     /locus_tag="L1V38_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1315629.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="L1V38_001068"
     CDS             14398..14736
                     /locus_tag="L1V38_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBN1315630.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V38_001069"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V38_001069"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBN1315631.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="L1V38_001070"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="L1V38_001070"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBN1315632.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="L1V38_001071"
     CDS             15893..16936
                     /locus_tag="L1V38_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBN1315633.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="L1V38_001072"
     CDS             17095..17823
                     /locus_tag="L1V38_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBN1315634.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="L1V38_001073"
     CDS             17939..18184
                     /locus_tag="L1V38_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1315635.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="L1V38_001074"
     CDS             18181..18399
                     /locus_tag="L1V38_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBN1315636.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="L1V38_001075"
     CDS             18535..19074
                     /locus_tag="L1V38_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBN1315637.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="L1V38_001076"
     CDS             19067..21340
                     /locus_tag="L1V38_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBN1315638.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="L1V38_001077"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="L1V38_001077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBN1315639.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="L1V38_001078"
     CDS             complement(22513..22767)
                     /locus_tag="L1V38_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBN1315640.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="L1V38_001079"
     CDS             complement(23167..23436)
                     /locus_tag="L1V38_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315641.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="L1V38_001080"
     CDS             complement(23906..24361)
                     /locus_tag="L1V38_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBN1315642.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="L1V38_001081"
     CDS             complement(24499..26427)
                     /locus_tag="L1V38_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1315643.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="L1V38_001082"
     CDS             complement(26624..27457)
                     /locus_tag="L1V38_001082"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBN1315644.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="L1V38_001083"
     CDS             complement(27649..28353)
                     /locus_tag="L1V38_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1315645.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="L1V38_001084"
     CDS             complement(28376..29002)
                     /locus_tag="L1V38_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1315646.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="L1V38_001085"
     CDS             29328..31703
                     /locus_tag="L1V38_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBN1315647.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="L1V38_001086"
     CDS             complement(31727..32218)
                     /locus_tag="L1V38_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBN1315648.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="L1V38_001087"
     CDS             32405..33325
                     /locus_tag="L1V38_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1315649.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="L1V38_001088"
     CDS             33479..33823
                     /locus_tag="L1V38_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBN1315650.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="L1V38_001089"
     CDS             complement(34013..34513)
                     /locus_tag="L1V38_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315651.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="L1V38_001090"
     tRNA            35041..35124
                     /locus_tag="L1V38_001090"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="L1V38_001091"
     CDS             complement(35448..>35882)
                     /locus_tag="L1V38_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1315652.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6262 c         7405 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DAFLWZ010000020        34856 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000020 DAFLWZ010000000
VERSION     DAFLWZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.020"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(507..2399)
                     /locus_tag="L1V38_001092"
     CDS             complement(507..2399)
                     /locus_tag="L1V38_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315653.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2396..4123)
                     /locus_tag="L1V38_001093"
     CDS             complement(2396..4123)
                     /locus_tag="L1V38_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315654.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4139..4789)
                     /locus_tag="L1V38_001094"
     CDS             complement(4139..4789)
                     /locus_tag="L1V38_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1315655.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4993..5289
                     /locus_tag="L1V38_001095"
     CDS             4993..5289
                     /locus_tag="L1V38_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1315656.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5481..6101
                     /locus_tag="L1V38_001096"
     CDS             5481..6101
                     /locus_tag="L1V38_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBN1315657.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6193..7359)
                     /locus_tag="L1V38_001097"
     CDS             complement(6193..7359)
                     /locus_tag="L1V38_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1315658.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7371..7724)
                     /locus_tag="L1V38_001098"
     CDS             complement(7371..7724)
                     /locus_tag="L1V38_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1315659.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7852..8874
                     /locus_tag="L1V38_001099"
     CDS             7852..8874
                     /locus_tag="L1V38_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBN1315660.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8893..9054
                     /locus_tag="L1V38_001100"
     CDS             8893..9054
                     /locus_tag="L1V38_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315661.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9313..9747)
                     /locus_tag="L1V38_001101"
     CDS             complement(9313..9747)
                     /locus_tag="L1V38_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315662.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9857..11716)
                     /locus_tag="L1V38_001102"
     CDS             complement(9857..11716)
                     /locus_tag="L1V38_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1315663.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11834..12994)
                     /locus_tag="L1V38_001103"
     CDS             complement(11834..12994)
                     /locus_tag="L1V38_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBN1315664.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13301..14725)
                     /gene="araA"
                     /locus_tag="L1V38_001104"
     CDS             complement(13301..14725)
                     /gene="araA"
                     /locus_tag="L1V38_001104"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBN1315665.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14741..15439)
                     /locus_tag="L1V38_001105"
     CDS             complement(14741..15439)
                     /locus_tag="L1V38_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1315666.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15396..17057)
                     /locus_tag="L1V38_001106"
     CDS             complement(15396..17057)
                     /locus_tag="L1V38_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBN1315667.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17275..18675
                     /locus_tag="L1V38_001107"
     CDS             17275..18675
                     /locus_tag="L1V38_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBN1315668.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18927..20006)
                     /locus_tag="L1V38_001108"
     CDS             complement(18927..20006)
                     /locus_tag="L1V38_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1315669.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(20092..21051)
                     /locus_tag="L1V38_001109"
     CDS             complement(20092..21051)
                     /locus_tag="L1V38_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1315670.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(21063..22574)
                     /locus_tag="L1V38_001110"
     CDS             complement(21063..22574)
                     /locus_tag="L1V38_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1315671.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22596..23159)
                     /locus_tag="L1V38_001111"
     CDS             complement(22596..23159)
                     /locus_tag="L1V38_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1315672.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23165..24028)
                     /locus_tag="L1V38_001112"
     CDS             complement(23165..24028)
                     /locus_tag="L1V38_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1315673.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(24042..24938)
                     /locus_tag="L1V38_001113"
     CDS             complement(24042..24938)
                     /locus_tag="L1V38_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315674.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(25113..26402)
                     /locus_tag="L1V38_001114"
     CDS             complement(25113..26402)
                     /locus_tag="L1V38_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1315675.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26374..27891)
                     /locus_tag="L1V38_001115"
     CDS             complement(26374..27891)
                     /locus_tag="L1V38_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1315676.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            28089..28979
                     /locus_tag="L1V38_001116"
     CDS             28089..28979
                     /locus_tag="L1V38_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBN1315677.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(29052..29876)
                     /gene="nadE"
                     /locus_tag="L1V38_001117"
     CDS             complement(29052..29876)
                     /gene="nadE"
                     /locus_tag="L1V38_001117"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBN1315678.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29888..31360)
                     /locus_tag="L1V38_001118"
     CDS             complement(29888..31360)
                     /locus_tag="L1V38_001118"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBN1315679.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31997..32359)
                     /locus_tag="L1V38_001119"
     CDS             complement(31997..32359)
                     /locus_tag="L1V38_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1315680.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32582..33334
                     /locus_tag="L1V38_001120"
     CDS             32582..33334
                     /locus_tag="L1V38_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1315681.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33474..34397)
                     /locus_tag="L1V38_001121"
     CDS             complement(33474..34397)
                     /locus_tag="L1V38_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315682.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34412..34684)
                     /locus_tag="L1V38_001122"
     CDS             complement(34412..34684)
                     /locus_tag="L1V38_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315683.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10286 a         7243 c         6020 g        11307 t
ORIGIN      
        1 aaaatagctc ctcctatttt tcgtttggtt gggcttatta ccgcagatgc aagcttttga
       61 acaccgttta aggaagaggt tgtgaaaaag tcgcttagtt tcgagtagta agaaaaattt
      121 tgtgaaaatg gctttctaca tttttgcata aatttggctt aataccgaga aactggcttt
      181 tgaacaccgt ttaccaagag gttgtgagcc tgccgtttaa ctccgagtca caaggagcaa
      241 tttcaaaaaa cagcttctca ggtttgttga ctattgtgac ttgtgaccga ggagttggca
      301 ggagaacacc gtttaaggaa gaggttgtaa aatcagcggt ttgacctgag tattagagat
      361 acaaaacgga aaaatagctt ctcatatttt gccgtttttt gagctaatac cgaaggacag
      421 ctgattgaac accgtttatt cggaaaaagg gactgtgaca cgacttttgt cacagcccct
      481 aaaaaaaata ataaatttgt actattctat gaagcttctt cttcagaaaa ctgactgtta
      541 taaagatctg catagaatcc gtctttttcc atcaatgtat cgtggtttcc tgtttctacg
      601 atcgaaccat gattcatcac aataatgttg tctgcatcgc gtattgtaga caagcggtga
      661 gcaacaacga aacttgtccg gttttccaat aggcggttca tcgctttttg aatcagtatt
      721 tctgttcgtg tatctacact agatgttgct tcatcaagga tcaggacatc tggatttgct
      781 aagaatgccc gcgcaattgt gattagctga cgctgccctt gcgaaatatt gcttgcatcc
      841 tcgtttaata cagtgttata tccttctggc aatttacgaa caaaatcgtc tacgtgagca
      901 gctttagcag cctcaatgat ttgttcgtct gttgcatcgt cgttcccata tttgatattg
      961 tcatagatac ttcctgtaaa cagccaagta tcttgcagta ccattgaaaa ctgtgcgcgc
     1021 aattcatcac gtgaaagatc acgggtatct acaccatcgt aacgaatact acctccagaa
     1081 acatcgtaga accgttcaag aaggttgatc agtgtcgtct tccctgcacc agtcggacct
     1141 acaatagcga ccatctcacc aggtttgaca tccaagttaa aatcagtcat tagcaagtta
     1201 tctggtgtgt agccgaattg aacattttca aaacgaactt tgtatggtgt atctttttct
     1261 tctggaaggc cagatttttc attggacatc tcttcttcat ccaacacttc aaatacccgt
     1321 tcggctgaag caactgttga ttggatagtg ttcatcaaac ttgcaagttg agtgattggt
     1381 tgagagaact gtgttgtata ttgcaagaac gcttgaacat cccctaatgt catgttccca
     1441 tttgcaactt ttactccgcc tagtacagcg acgaacacat agcctagatt tttaacgaaa
     1501 ttcatcaacg gcatgatgat tgccgaaata aattgagctt tccaaccagc ggcatacaga
     1561 ttctgatttt ctttttcaaa tacttcctgg tctttttcag tatgattgaa tgttttaaca
     1621 atggtatgac caccatatgt ttcttctact tggttattca ataaacctaa acttttttgc
     1681 tgatctgcga aaaacacttg tgatttcggc gctacgatca tcacgatgat caagcttaaa
     1741 gggatcatca ataacgcgac taacgtcaat tgccagctga ttgaaagcat catcacgatg
     1801 accccaatca atgtgactgc actagttaca aattgagtca aattttgctg cagcgtgctt
     1861 gcgatgttat ccatatcatt gattgctcga gacatgatat ccccatttgt atgtgtatca
     1921 taataggaaa tcggtacacg attcattttg gcttccaaat catgacgtaa ttcataaact
     1981 gttcgttggg aaacacgtgt cataataaat tgctgtaaaa agttgaatac agcagaaatc
     2041 aaatacatca cgattactgt cgcaatgatc tgcgcgattt tatcaaagtc tatcggaaat
     2101 tttgttactt gttggccttg ttgcatctgt tgagcgccag ccattacacc tttgaatatt
     2161 tctgtggttg ctttccccaa gacctttggt gtttggattt ggaagatcac ggctgctatt
     2221 gctagtacaa atacagcgat gatcgcaacc atacgtttag acatatagcc aaacaatcgg
     2281 cgtaccgttc cccagaaatt tttaggcttt tcacctttta caccgagatt tctgccaggt
     2341 ccaccatgtc ctggaccgcc tgctggtcca tgagagggac gtgtgtttgt tttactcatg
     2401 ctaagtcctc ctctcttagt tgtgaatgaa cgatttcttg ataagtttcg tttgttgcta
     2461 atagttcttc atgtgttcct ttgccaacca gttttccttc atctagcaca aggatcatat
     2521 ctgcatccat tactgtactt actcgttgag caactaaaac ggtgatactt tctttcatat
     2581 tcgttttcaa tgcttggcga agattggcat ccgttttgaa atccaacgct gagaaggaat
     2641 catcaaacac atagatatct gctgttttga ctaatgcccg tgcaattgcc agacgctgtc
     2701 tttgtccacc agagaagttt cctcctcctt gttccacatg gctatctaag ccatcttcca
     2761 tctctgaaac aaaatcttta gcttgtgcga tttctaatgc tttccaaatc atttcatctg
     2821 ttgcatccgg cttaccatac tgcatattgt ctcggatcgt tccagagaac agaactgctt
     2881 tttgaggaac aaagcccatt aattctcgca aattatattg agtcatgtca ctaatgtccg
     2941 ttccatttat ttggatcgaa ccagattcga tgtcatataa tcgagggatc aaattgacta
     3001 aggtcgtttt acctgaacca gtccccccta tgattgcgac gatctcgccc gacttggctt
     3061 ggaaatcaat atcttccaat gcaagttttt ctgctccatg atatcgataa ttgacatgat
     3121 tgaaggccaa tgttgcgttt tttccagcaa aagaaactgt tttaggattt tcagggtcat
     3181 ggataccgat tttttcatcc aacacttcat taatacggtc agctgaagct tgtgcacgag
     3241 gcaccatgat aaaaatagcg gaaagcatca taaagctgat caagatctgc atcgcataag
     3301 tcataaatgc aatcagatta ccgacttcca aagtcatatc tgctatgtag tgtccaccaa
     3361 accaagtgat tgctacgttt gtaccgctca tgatcaatgt catcattggc atcatcaatg
     3421 cgacgatcgt attaactttg attgccgtat ttgtataatc tttattcgct aaatcaaaac
     3481 gattttcttc aaagcgtgtc ttatcgaatg ctcgaatcac tctgacccct gtcaatcctt
     3541 ctcgaaatac caggtttaaa cggtcagttt tcttttgcat acttttgaat aatggaacag
     3601 caaagtacat gattccgccg atcaaaataa tcattactgg gatgacaact aagaagattt
     3661 ttgtcaactg atgatctttt tgataagcaa gtatgctcgc gccaatcaac gtgattggtg
     3721 cattgatcat catacgtaaa aacatttgtg taaccatttg gatttgagtc acatcattgg
     3781 tcgttcttgt gatcaaagag gccgttccat atttatcaaa cgcatctttt gtcagactct
     3841 ctgatttttt atagacatcc gtacgcaatt gcttacccag tttctgtgat tcacgagtag
     3901 caaaaaatgt atttgcgata gcagctaaga tactgatcaa agaaaagccg atcatcacaa
     3961 aacctgtatg ccaaatataa tcgacatctc cttgcgctac ccctttatca ataatattgg
     4021 aggtaagtgt cggcaaatat aaatctgcca gtacttggat caccatgaaa actgcagctg
     4081 caattgctga agtcaaggag atccgtttta cgatttttag catctagttc ccttctttct
     4141 atttatatac tccgtttttc agccaagaaa gtttcaaatt gaattcactg attgcttgct
     4201 ctactgagta atcttcagat gttgaaaata agcgatacga atgcgcaatt gttgtaaata
     4261 cagtattcat cactaattgg atcagtaatt ccaattcatg atcatttttt actttcagct
     4321 tcgtccgatc gatcaattca agcaactctt ttgcatcttg tttgtgttct ttatgtggat
     4381 cgtgaggcgt tttttggcga ctcgtatgag gagcgacttt tcttgaggca cggtaatcca
     4441 tgttcataaa caagttacga taaaaagaag cattctcgcc ttccaaaatc tcataaatca
     4501 ttttagaaaa ataggattcg aatcctttga atagatcacc atcggattct ttcattagtt
     4561 gtaacatatc tttagagctg tcacgtctca ttgtctcaaa gtaataaaaa taaagatcct
     4621 ctttatcttc aaaatactga tagaaactgc ctctagggat atccgctaat ttgacgatat
     4681 tagcaatcga agcttctttt aagggtactc tagaaaactc gattctcgca gcctcgatta
     4741 gtcttttttg tttttcttta ggcaaatgga aaaatgtctg tgtcggcata tggattctcc
     4801 tttctttcaa gatgacacat tgtcatatga cgctatgtca ttataacacc tcctacctgt
     4861 tttgcaagac atttgcatag tttttttcat tatcatccga tacattaaaa aagtgataag
     4921 aggaatcctt ccatttgaat taatgagagt tgcccattaa aatagccaca tactaaacaa
     4981 aggatgagat aaatggccca atcaattagt gtccaagact tcaataaatt gcctctcgat
     5041 gctgacagca tcgttttaga tacaagaaat accttagatt acacaaaaaa ccacttaagc
     5101 cactcgcttt ctatccccgc tgctatcttg ccaagacaat taaaaaatct agatccaaag
     5161 aaactttatt atattctaag ctatacaggc aggcgatcag aagcattagc cgatcaactt
     5221 actgctaatg gttttcgtgc tgtttatatc attggtggga tggaagctct tcagtcgagt
     5281 gttgcttgaa tattgcttgt tagattcaaa agaggctgtg acaaaaaatc gtgtcacagc
     5341 ctcttttata ccctgtcttt ttttagttat ttattcttca accttatcaa tatgacttga
     5401 tagccttttc tttttcgagt aaactgattt tgttagtcat agttataaca atcatagcaa
     5461 taaaaggaga aggtaagcat atggcatctg ttttagtagt caaaggtcat cccctaactg
     5521 cagaagaatc gcgcacagtt aaggcattga cgtctttttt aacaagttat aaagaaaatc
     5581 atccagatga tgaagtgact gttttggaac tttatcgcga tgatattccg gaaatcgatg
     5641 aagaattatt atcaggttgg gaagcattac gtgctggtgc agaattcact tccttatcag
     5701 aaagtcaaca acaaaaaatt gctcgtttca atgaattgac tgatcagttc cttgctgctg
     5761 ataaaatcgt tatcgcaaac gccttatgga atctaaatat cccaacaaaa ttaaaagctt
     5821 ggttcgatac cgtcaatgta gctggaaaaa cgttccgcta tacagaaaac gggccagaag
     5881 gattagtgac aggtaaaaaa gcactgcaca tccaatctaa tggcggtgta tacaacggac
     5941 aagactttgc ctctcaatat gtaaaaggta ttttaaactt tgtaggcatc gatcaagtag
     6001 atcagctatt catcgaagga atcgattatg accctgaccg tgcagatgag ttgatgcaaa
     6061 atgcattaga taaagctgct gctttaggta aatcatttta aaaattgaga taaatgcata
     6121 caaaagagac agaggaaaaa atcttcaaag cagcatttgt gccttggata ttttcccatc
     6181 tgtctctttt tgttattctt tctgcttttt caacggattt tcttcataaa gagaagagat
     6241 tgttgtgtac cattcaaaaa catgagtaat cactacttta gctgctgcat aaacaggaat
     6301 ccccaagatc acaccgatga ttccgaacaa tttcccagaa gtcagcagaa ctaataaaat
     6361 cgttactgga tggattgcta actgattccc tagtactaat ggagagatca agcgtccttc
     6421 tattgtctgc tctactgcaa aaacgatcag tactttgatg atcatgaatg gacctgctac
     6481 aatggctaaa aagatagccg gaatcatcgc taaaaatgat cctaagtaag ggatcaggtt
     6541 taaaaaaccc gcaataatcc ccaacgtgac agcatactct aaaccaatga ccgcaaaacc
     6601 aatcataaac atgattgcca cagcaaaagc cacagttagt tgtcctctta tataagaaga
     6661 aacttgacta ttcatttcac tcagcacatt caacgtcggt ttttgcatgc gtgtcggtaa
     6721 aaatttgaca aaataaggtg ctaattgttt accgtctttc aatagataaa ataagataaa
     6781 cggcatcgtc agcagagcca ctaaaatagt cgctaccgcg ccgacaaaac ttccaagact
     6841 ctgaactgta ctcttagata tatcttggat catatcgcct gccgaattca tgaacttatc
     6901 acctgctgtt tccaactgtt cgcgaaattg gttgaacagc gggtcccgca aaatctcggt
     6961 taatttatta tcaatcgtat ctacatattg agggaagtta ctgatgaagc tcactgtttg
     7021 ttcctgaatc ttagggatga tcactacgct cccccatgcg attagtgcaa caaccaaaac
     7081 aaacagccca atgatactgt aaagccttgg tacttttcgc ttttcaaagt aatcaactac
     7141 cggattcatc aagtaataca agattcctgc taaaatgata ggcagaccta cgattgctaa
     7201 aaattgccag attggtgcaa acaaatatga aacttttgta aataaaaaga cgatcagcaa
     7261 tattaacaat acaacaagta aggctgtgac tacttgatta tttaaaaacc agcgccaaaa
     7321 ccacgatacc ggtctgttct tcttattttt tccttccata attcctcctg ttagttataa
     7381 aaaatttggc ttcccaaacc aatagcaggc agtctatgcg gatgaagata gattccattt
     7441 gcaatttgtc cttcttctgg acaagcatca aaaatcaatg atacgtgagc tactgtcttt
     7501 aaattcccat tggccatcgg accgacataa tcgatcgtat atacctgatc atcaaaagca
     7561 attgttccgc ctgctttcaa agaaaaaggt tcgtcttttg atacttcttg aatcaccgaa
     7621 tattttcgta aggcagctgt tgctgtttta tcgaacaaaa tcagcatggg ttcttccttg
     7681 tttattgctt ctgtcccaat ttctgtaatc tttgcctgaa tcattgcact ctctccttta
     7741 attgctttca aaaacagtat aacacattct cattctttag ccgtgtggaa taattatgtg
     7801 atagaataaa aacgaaaact atttcattac aattaggagg aatcagctca tatgatcgaa
     7861 aagataattt taggaaccta tacgcgtcgc gaaagtaaag gaatctatac gatcgacctt
     7921 gatacagaaa aagaagaatt agccaacctt tcattagctg ttgaagaaaa tagccctacc
     7981 tatgtagcaa aaagtaaagc tggcaatctt tacacagtta ctagtgtgga tggattaggt
     8041 ggtgccggtg cgtacgataa ggattttcat tttttgaatg cggtaacaga gtctggcgct
     8101 cctttgtgtt atgtagcggt tgatgaagca cgtcaattac tatacggggc gaactatcat
     8161 aaaggtgaag taaatgtcta ccatatatta ggagatggcg aactgaaagc agcagattca
     8221 atattccatc aagaagcgac aggtcctcat aaaaaccaag atcatgcgca tgtccactat
     8281 acggatctga ctcctgacca acgattagtc gtatgtgatc ttggtacaga tcgtgtgtat
     8341 acttatgatg tgtccgaaaa cggcaaattg aatcttgtaa ctaccttcac tgcagagcca
     8401 ggaacaggcc ctcgccatct tgtctttcat ccaaatggac aattcgctta tttatttggt
     8461 gaattagaca gcacagtccg cgtgctttct tataataaag aaacaggtgc ttttgaagaa
     8521 ttacagaaaa tatcgacctt gccagaagaa ttcgacggtg aaaatggagg ggcagctatc
     8581 cgcatttcaa atgatggcaa gttcctttat gcttctaacc gaggacataa ctcgattgct
     8641 gtattcgcag tttttgaaga tggttcccac attcaaaaca agcaaatcat ctcaacagaa
     8701 ggggattttc cccgcgattt cgcactagat ccaagcaata attttgtcgt gtgtgccaat
     8761 cagaacaccg ataatctgac attatatcgc cgtcatcctg aaacaggatt actggaatta
     8821 ctgaaaaaag atgtctatgt accagaatgt gtctgtgttt attttgatcg ttagtaagaa
     8881 aaggagaatg aaatgaatca gcaagacgta ttagacagac tacgggaaga actaaatatt
     8941 cctttctttg atgggaaaat cgaagataaa gagtatagcg aagaggaata tcagaaactc
     9001 aaagccgatt tacagaacta ctttgaacaa tatgtacaga atgtagaaaa ctaatcagct
     9061 ttccatacta tctgaaaaga acatcaggac aagacttttc cgtctatcct gatgttcttt
     9121 tctacaaata aaaaaccgcc gagatggtta gactcgacgg aaaaggagta tttactcgat
     9181 tttgagtaag tacaaggttg ttgttggtta taggtatgtc attatcataa aggattttga
     9241 tcactctatc ataaaggtaa tattacattt atattagata actctagttt ttattgttat
     9301 caaagatttc ttttattttt tcaacaacaa attagtcatt ttttggatgg cagctgtcaa
     9361 ttggtctgtc gcttggtctt gttttgcttc agatgtattg aatagatctt catctacccc
     9421 tgattcaaga tcgatacttt ggatcatttc ttcacagcct gctacatatg aaagataagc
     9481 tttttcaaaa tttttatgaa tgcccattgc ttttgctggt ggacgcaaag tactgacttt
     9541 cataagcatt gcccgatatt tttttgttcc ttcttcaaat aacaggatga tctcttcaag
     9601 agtcgatttg tccagttcac ttgtttttcc ttcatcaatt gcgtttctga tcacttcata
     9661 tttcggatgc attccttctc cgattgcttc tgtttccttg acgatttgat cgatggactg
     9721 cacataatag ccaatattcg gtaacatgtt cgttttccta ctttctccat tgttgttatt
     9781 atttattcta cttgttttta tcctcaaatg acaagtactt gaaaaaattt aatggtttct
     9841 atacagctcg ccattcttat tcgtgctcaa agaaaccatc tgctaaacta tattgtttcc
     9901 ctgcgacaat gtcatattgg atcaattgat attcgtcgta aatctcttgt tgcgagcgat
     9961 tgaattgcgc ttctttatac cactgtccgt tttgatagta cagttctcgt tcaaacgccg
    10021 gaagttcctg ttctaatgat aaaagcagct gataaaagcc atttgttgtc tgattcgtct
    10081 gttccattag attcgctgca aaataaaacg gactggtgat tgcatcgtga gtcgtttgct
    10141 tttctaattc tcctttactg tcgaacataa gaaattgtgt ttcatgcaat gtttgtttgt
    10201 cattttttgc ttggatcgta tctgaataga tccctggaag atgatccccc caaaaaacaa
    10261 ctaaagtcct tctagaaaga ttcttcaatt cttccgtgaa ctgcttcagt gccgtgctgc
    10321 tataggaaat atcttgcaga taattctcta agtcaagtgt cccacttcca tctgaagttt
    10381 ttgcaggata gtctagatta tcatactttc catcgtaggg catatgtgtc tgcatcgtga
    10441 ctaaatgaat gaactgaggt gttttttctt ccttgagaag tgtcattact tctttgtaag
    10501 ctgactcatc agaaatatat ggattattct ctatcgtatc cgtataggtc atcgtacgct
    10561 cgctgatgaa ctggtcaaat cctaatgtct gataaacatc ctctctttta tacatcgaag
    10621 tattgtatgg atggatcgct gtcgtctggt atgattgtgc gtttaacgct gaaacgatag
    10681 aaggaagctg atccattttt ggtacaagca tcgtgtaagg ggtggtgagt tgcgcattaa
    10741 ataacgccat agaaaaacca gtcaatgctt caaattcgat atttgctgtt ccaccgccat
    10801 agttttgaga aagcatattg ccactatatg tttgatcagc tacttcataa taatctgcca
    10861 atggctcacc agatacttct acgccgttta atcgactagg atctgagaaa ctttcactca
    10921 tcacgaacac gatgttcggc gactcttcct ctacagtttt atttttttca tcggctagct
    10981 tctggtattt ttcagtgatt tctttgatct tttctttcga atatccttca ggttcatcca
    11041 ttggttctac cttcagattg tacaaaaacc caccgataaa accagtgtta tagtagttca
    11101 ttttctggct gtaaggtatc catagtgccg ttttattata tgcttttcgc aacaaattat
    11161 cgggattgtt gaaattactg atatacccta gcagtccaat tgccacaagc agtgtcgtta
    11221 atcggatcaa ttggaatcgc cttccttttt tcaggcttcg aaacatgtac cagcaaaaca
    11281 atcctatcac ggttcctgcg gcagctaaga tcactgtaaa cagcatagtg ccggtcatat
    11341 ctttcagcaa tccgatttca gtgatcatct tcaaatcgtc tggataaatc ggttcttgcc
    11401 gataactcat tttcatataa tttgcaaaac ctaatacacc gatggctacg acatacgtaa
    11461 gggaacctaa agggacagat cctgctagtg caatcagaaa aataagaata atcagcaaga
    11521 cgagacaggc taagaagaat ttttccgtat gccaagaaaa agcaaatttc aacgcaaggt
    11581 ctacggatag atcattttga caccactgca aaaataaatt actaaaaaca acaagaaaaa
    11641 agatactgat gattgctgct gttcctttta aaatcttttt ctgtttggtc gaaagtctgc
    11701 ttatatatct tttcaaatgc ttgctccttc atttctatca ataaaagaat gttgcttctc
    11761 ttattttagt tgtacgaaat tcgaaagtaa agaacggaaa gaagaattaa tgaaatccaa
    11821 atattctctt tctttatggc ctttctggtt tctttaataa gcggaccttt cgtactccag
    11881 aaattttttc tagctgttgt ttcacttgat tgagctgttc aaaatcagta ctgtctatgt
    11941 caatcaatat gtagacatgc tcattcttat ggttacgcga tatatctgcg atcgctagct
    12001 cgttctcatt cagcagagaa aatatctctg ctaatatatt ggttttcttt tgataaaata
    12061 tagtgaatcg aaacggcgct tggaaaaaca ttcgtgcgga tggataattg accgcttctc
    12121 taaccgtacc gaacaaaaga taatctttta aggcttcaac tgccaaacgt ccgctgtctg
    12181 ccaaagcttc ctgagtcgat ccccctagat gaggcaacat aagtatacgg tcattttcta
    12241 agaactcttc ttctggaaaa tcagtcaagt atttagccag atgttgtttt tccaatgctt
    12301 gcataacagc atatttatca acaatttcac ttcttcctac attgataagt acagcatctt
    12361 ttttcatttt ttctatattc gcctgatcga tcaatccttt tgtatcttct gtcaacggca
    12421 gcatgactac gatgtaatcc gaggtagaaa gaactgtttc taaatctgct tgccgaacat
    12481 aatccaactg ggcatcgcgg atagaataac ccaagacatc catccctaag ctatagcaac
    12541 ttagcgctac ttttgtgcct atcgctccaa gaccaagaag accgatggtt ttgccttgca
    12601 attctcgtcc cacataagca cttcttttgt tttctgcctg ttctaaaata ttaggacctg
    12661 ttagtgtttg taccatacga cttgcttcga ttatcggacg ggaagataag agcaaacagc
    12721 acaaaacaag ctcttttact gcattagcat ttacacctgg tgtattcatg acgatcgtcc
    12781 cgttttcaga agctttttca acgttgatcg tgttcacccc aacaccagct cttgaaattg
    12841 ctagcaaatc tggtgtaagc cattcatctt tcactttcgt actacgaata actattcctt
    12901 cggctggcaa atcatctatt attttgaaat attccccttg taacttttct atctcttgtt
    12961 ctggaatagc atcaatcaaa tgaacgtgat acataaaacc ccctccttac taacaagtat
    13021 ctcgaaattt ctgcaattag acaactgttt accatttgac ttcctagaag caaaaagagc
    13081 agttagagca gagtaggctg agtgataaaa ataaggctat gacaagttac tgccataagc
    13141 cttattttcg agagcaaaat attgagggtg agatatcttg ataaatggtg ttccgttagc
    13201 tgacattgat aataagacta aatttcaaaa aagttgaaaa gcaaatttcg tcaatctctt
    13261 cttatttctt aaaactaagt ggctttttca caacctcttt ttatctaata accactgttt
    13321 ccaactcaac taattttgcc cacgtttcaa tttgatctgt tgttagattt agcgagacaa
    13381 cggtatgatg accgccacct gcctgaatcc atgaatggac accttcatgg aaattcggtt
    13441 tagttttcca taacacacgt gcaacaggta aattaggtgc ttcagtcgtt ggttcaaagg
    13501 cttctacttc attgatcagc agtttataat gcgtaccgaa atctgccatc gatacgacta
    13561 ccccttctcc tgctttccca tcaaatacaa gacgcgccgg atcttctcta tctcccattg
    13621 ataaaggaga aacaacgatt cttggtttcg tcgcagcaag cgtcggatct acttccatca
    13681 tatgggattc caagattgct tcttggccac tagctagctc gtaagtataa tcttccatga
    13741 atcctgtatc tttccctcga gccatgattt tcagcaaccg atcaatcgct gcagttttcc
    13801 agtcgccttc cccagcaaaa ccgtatcctt ctgccatcaa acgttgtaca gctagtccag
    13861 gtagttgttt cattccatac aggtcttcaa aattagtcgt aaaagcgtta tagcctcctt
    13921 cttctaagaa acggcgaata ccgatttcct gctgagcttg tacttttaca tgttcctccc
    13981 atgtcttttc ttcataatca ccatagtcga aggtatacaa ttccttgtac tcttcaaata
    14041 attgatcgac ttcttcgtct gatacgcgat cgattacttg tacaagatct ccgataccaa
    14101 aataatcaac agtccaacca aattgaatct gtgcttccac tttgtctcct tctgtgacac
    14161 ccacgtttct catgttgtca ccaaaacgag ccacttttat tccaaaactt tcattatagg
    14221 ctactgcaac atccatccaa tcagcaatct ctttttggat ctcaggtcgt ttccagtagc
    14281 caacgacgat tttattttgt ttatttaatc gagcattgat gaacccatat tcgcggtcac
    14341 catgagcgga ttgatttaaa ttcatgaaat ccatatcgat cgttttccaa ggaatgcttt
    14401 cgttatattg cgtagctaaa tgaagcaatg gtttttgtag aagctttgtc ccgcggatcc
    14461 acatttttgc tggtgagaaa gtatgcatcc aagtgatcac acctgctact tcttctcgat
    14521 aattgacctc tttcatgatt tttgtgatcg tatcagcagt aactgctaat tcttgaaggc
    14581 ggattggata aggcaattgg ccattttcat tcagttcatc gaccatttct tgtgcatgtt
    14641 tctttacttc tcgcagtgct tcttccccat ataaatgctg tgatcctaca acaaaccaaa
    14701 attctttttc tccaatattc aacataatta gccactcctt ttatttgttt tgtccgtaat
    14761 acgcattttt tccgtgtttt cgtaaataat gtttatctaa aatccgttga ggcagctctt
    14821 ctgaaaatga attgagctgt ctggtaaata aattcatctt gcatacttca tctagtacga
    14881 ctgcgttcat taccgcactt tgcgcatctt tcccccaagt aaatggaccg tgtccgtgta
    14941 aaagtacccc tggaattgct aagggatcaa ttttgcgttc tttgaatgtt tctatgataa
    15001 cttttcctgt ttcatattcg tacccgctgt cgatttcctg ttgtgtcaaa aatcgagcac
    15061 aaggtaccga tccataaaaa gtatctgcat gcgtcgtccc catcgcagga acatccaatc
    15121 ctgcttgtgc ccagatcgtc gcccatgtcg agtgagtatg gacgattcct ccgatttgag
    15181 gaaatgaacg atataaaaca gcatgagtag gcgtatccga agagggattg agtttacctt
    15241 caatgatatg attgtccaag tccacaacga ccatgtcgtc tgctgtcatc tcttcataac
    15301 tgactccgct aggtttgata acgaaatatc gtgtttcagg atcaaaagcg ctcacatttc
    15361 cccatgtata tttgacgagt ccgtgtttag gcaagtcaag atttgcttgg tatacttctt
    15421 ctttcagttg ttccagcatt ttctatcact cctttttctt gcaattgatg aatcgctgtt
    15481 ttttcaatgt cgatcccctc acggtaacgt ctcataaata tctgatagcc tgctatttct
    15541 tctgctgaag gtgtgatggt gattccttgg tcttgtccaa acacgtcttc tgccaagaag
    15601 ttttctaaag acttcccatg tcgatccatc atataggctg ctaataacgc gattccccac
    15661 gctccacctt ctccggctgt gtccatcact gtaactggtg cctccatagc agatgctaga
    15721 atccgctgtc caacttctgg tgttttaaaa atccccccat gccccactaa acgatcaatt
    15781 tggacattct cagatttcaa tatatccatt ccgattctca ttgcaccaaa agcactggct
    15841 aaatggatcc gcatgaaatt cgctaaatca aaacggctac ctggtgtacg tacaaataat
    15901 ggccttcctt catttactcc tgtaatgttt tcaccggaaa aataaccata agaaagtaat
    15961 cccccgcaat ccgtatcgcc ttctagcgct ttgttgaata ataccgtgaa taatttatct
    16021 ctgcttatct ccatacccaa agaattggta aattcttcaa aaatactgac ccaagcattg
    16081 atatccgaag agcagttatt cgtatgaacc atgcctacta gttctcctga aggtgtagtg
    16141 accatgtcga tttccggatg gacattttct agttcttttt ctaatacgat catagcgaag
    16201 gcggaagtac cagccgaaat gttccctgtc cctttggcta cactgttcgt agcgaccata
    16261 ccggttcctg catccccttc tggcggacaa accgggattc ctggtctcaa atttcccgta
    16321 gggtcgatca gataagcccc tgattcgctt aacttgccag cttcttctcc tgctactaga
    16381 actttaggca aaatgtgatc caagtcaatc gctacgtgcg ctttttcgat taactgacca
    16441 aaaatatttt tcatttcttg atggtaggtt ttcgttgaag gatcgatagg aaacatgcct
    16501 gatgcatctc ctacgcctag tactttctca ccagtaagct gccaatggac ataacctgca
    16561 agcgttgtca aaaaattaat ttctttcaca tgttcttctt tattcaaaat agattgatac
    16621 aaatgagcga tactccatct ctgcggaata ttgtattgaa atttttccgt taatattcgt
    16681 tctgcttctt cagtgattgt atttcgccaa gtacgaaatg gtactagtaa ctgttccttg
    16741 ctatcaaatg ctagataacc gtgcatcatt gcactgaacc caatcgaccc gattgtcgta
    16801 agattctcgc catagatttc gaatacttct gctgccattt ttcggtaact gacgcgcagt
    16861 cctttccaaa tatcttctaa tgaataggtc cagataccat tttctagttt gttttcccac
    16921 tcataactac cagcggcaat aggagtaaaa gatgaatcaa tcaatacagc tttgatccta
    16981 gttgatccaa actcaatccc taaagatgta cgaccatcta tgacatctaa catactttgc
    17041 gcatttactt ccttcataat gatttaactc cctccttctc gtcaaacctg atcaaaccgt
    17101 ctttttagta gcgcttacaa tgattattgt atacttttgt acgtacatgt caagcagtta
    17161 tttacaagaa tacaataaaa aacacttgtt ttgtacgtac ataagttata aaatgaaatt
    17221 gcttacaaaa tctgatcaac cgccttctcg aaattctaga aggagagaat acttatgaaa
    17281 aaagaaaaaa aagtttcctc atcgtttatt tatttttttg gcgcatttgg cggcattcta
    17341 tttggatatg atattggtgt tatgaccggc gccttacctt ttttacagca tgattggggt
    17401 ttggcaggta aagcttcttt gataggatgg atcacgtctt cggtcatgtt aggtgcgatc
    17461 cttggcggct ctttatctgg tcttctttct gataagcttg gacgacgaaa aatgattctt
    17521 ctttctgcac ttatttttat ggctggttct gtcctttctg catctgcccc tcacaatggt
    17581 tcttattttc tgattgcagc aaggattctt ctaggtttag ctgttggcgc tgcatctgcc
    17641 ctagttcctg cttatatgtc tgaaatggct cctgctagac taaggggaag attgtcaggg
    17701 atcaatcaag tgatgattgc ttctggcatg ctcctttcct atgttgcaga ttatttgcta
    17761 aaagggttgc ctgaaacgat ggcttggcgc gtgatgttag ggctcgctgc tgtccccgcg
    17821 ctgattttat ttttcggtgt tttagctcta ccagagtcac cgcgttttct tatgcaatct
    17881 ggccgcttgg aagaggcaaa aagagtattg aactatattc ggacaccaaa agaagctgaa
    17941 caggaattcg aacaaatcca gctgaatgtc aaacaagaaa agacaaccgg aacttcttgg
    18001 catactttgt ttttagaaaa atatcgttcc ttagtcattg ccggtattgg tgtagcagta
    18061 ttccagcaat ttcaaggagc taatgctatt ttttactata ttccgctgat cgtagaaaaa
    18121 gcgactgggc atgcagcgag cgatgcattg atgtggccga tcatccaagg aatcatttta
    18181 gttgctggtt ctttgctctt tttggttatt gcagacaagt tcaatcggcg aactttattg
    18241 aaaataggcg gtagcgtgat gggactttct ttcatcctac cagctgtttt aggaactgta
    18301 ctggatgctc atacaaattc gttgttgatt ctcttgtttt tatgtattta tgtcgcattt
    18361 tattcttgca catgggctcc actgacatgg gtaatcgtag gcgaaatatt cccactagct
    18421 gtccgcgggc gagcatctgg cctagcctct tcttttaatt ggattggttc tttcctagtt
    18481 ggcttgcttt ttcctgtgat gactgcttct atgtctcaag aaatcgtttt cggcattttt
    18541 gggatcatct gctttttagg ggttttattt attcaagaga tcgtaccaga aactcgtggg
    18601 aaatctttag aggaaatcga acaaagtgca tctaaaaaaa cttatcctaa acgtatttct
    18661 atccatcatt cttaaagagg ttgtgacaga agtggtcagc ttcaagaaat aagaaggaac
    18721 cgcttagttt ccagtcacaa ggaacaattt caaaaaacag cttctcatgt ttgatgaata
    18781 ttgtgacttg tgaccagttg gtaggagaac accgtttagt ggagaggtgg tgaaagaaac
    18841 gttcagcctt gagcgatgac aaaagctctc acaaacattg cgacgagtaa ccgtaggagc
    18901 aataagaggc ggtaaaaacc cgtctcttat ttttcgtttt ctttcactgt ttcccgttca
    18961 actagtacag gttcatagag aatatttggc tgtgcctgtc ctttttcaat cgttgtgacg
    19021 atccaccgtg cggcatcttg tcccaacttt tcttttggat gcgtcaatgt tgtcaatttt
    19081 ttattcccta aatggcttaa agaagaatcg tctgttccta cgatcgatag gtcatctgga
    19141 atatgatagc cattttctgt caacttatct agcattaaac tagctatttg atcgttatag
    19201 caaatgatgc catctaaagc ttgttcttct ttcaaccgtt gtactgtttt ttcagcgatt
    19261 gtttctcgtg tttccgtggt gaaagtaatg atatcttccg tcaaaaaacg cacattatac
    19321 tgttcacacg cgctgataaa acctttcatc ctgtattttc cttgaagatc gtcgattttt
    19381 gtgatgaaca acagacgctg atgtcctttt tttatcaaat attctgctgc cataaaaccg
    19441 actttcacat catctaaaca aatataagag gcatttaact cttcataagc agcattgatc
    19501 atcaccatcg gaatgccttg ttctctcaaa gcaacataaa gtgctaagtt tgggttatac
    19561 tgattacttt tcgtaggctc aacgatcaaa ccatctaccc cataagcaat cattttcttc
    19621 aaacactctt tctccaattc gtgatcgtta ttcgtactgg ctaaaagcaa tgaataccca
    19681 gattctcgta attcattttc gattcctcgg ataatcgacg gaaaaatata atcagagaga
    19741 tatgtggtga tgacaccgat cgtttttgtt ctgttcaatg gtgttttttc tttcttatag
    19801 ctgtcatcta catatgtgcc cgaccctttt tctttacgca gatagccctc atttaccaac
    19861 acagcgattg cttgccgaat cgtatgtctg ctgacgtcat atatttcttg cagcttgaat
    19921 tctgagggaa tggttgtatt tacttcgtat tcctcacgaa ggatcttttg ttttatctct
    19981 tctgcaatat cttgatattt tgccatttgc cttgcccctt tttatttgta cgtacatata
    20041 tcataacgag tctgcaaggt ttattcaagc aaaaatcaag gtttcttgtg ctcataaggc
    20101 atacggaaca ggttcaccaa attctggaaa tccttgctca ttccacgtaa agcattgcgc
    20161 gttcgcgtgc cgattaggat tgtctaacgg atcccctttt tggttcttct ctggtcgagc
    20221 atgatagatc aaaatatcaa agcacccgtc ttctgaaacc gtaaacgagt tgtgaccagg
    20281 accaaattgc ttattttttt tagaagaaac gaatactggc tccgataatt tatgccatga
    20341 ttcttttaat aaaagattct tgtgctcatc agcccacagc aggcccatgg catagttttc
    20401 atctgttgca ctaccagaat acgtaatgaa tattttccca ttgcgagtaa ggactgctgg
    20461 accttcattt actgaaaaac cccgtttttc ccattcatac tcaggtatag aaaggaggat
    20521 ctgcttcccc tttaacgtcc aaggattatc catttcggat agataaagat tagaattccc
    20581 agtaatttca ggatcttgtt gggcccacac ataatatagc tttccttgag aagagaaagt
    20641 tgttccgtct aaactgaaag tttccctttt cgtttttatt tgtccctttt ctatccaatc
    20701 tgtattcatt ggatctatat gctgattttc aagtacgaac atgcggtgat gatgagattc
    20761 atcacgtata gttttatgat tgcttgcagc aaagtaaata taccattttc cattgatata
    20821 atggacttca ggtgcccaga tcaattcact catcggtcct tcttcatgag cctgccatac
    20881 aatcaggctt gcagcatgtt ctaattcatt cagtgacttt gcccttctta attcaatcac
    20941 ttggtagcct ggaaccgatc ctgtaaaata ataataacca tctgtatgtt tatataccca
    21001 aggatctgcc cgttgccgaa cgataggatt attataaagt gtcttcatca taacaaattt
    21061 cctcacattt tctttattct aattacattc caagagtatt tttctatccc tacatttaat
    21121 tcgtcatgtt tttctattga aaaatagttt atttcaggtt ttattttttc tggttcttca
    21181 cgtgtatttt tgtccaacag atcgctactg gttaatgtgt agtgctctcc ttgatctagc
    21241 aaattgaaat catgttcaat cgttatcttt tgttgttcat ttgtgcgatt gatcaagaaa
    21301 atagtcagct gattgccgtt atctacgatc acactgtcca cataaggaac attttttatc
    21361 ttttcacaat cataaacagg gcaaatgatt tgttgtttca atacttgacc tttagcatat
    21421 ttcgataagt gttgcatcac ataataagtt ggattcctcc atgcttgtcc tttagcatct
    21481 gtcagtatta aaggtattgt gtttactaac aatgattgac aactaatctt tacgcgatct
    21541 gcgtgtcgta aaatagccag ccctaatgaa ccaaataata atgtatcttc catagtaaag
    21601 taacaccaat cgatgggact accgacttca aaatccctat gtcttttttc cggttgggca
    21661 tgtacattcc attcatcaaa cgctagatac attgttttct cacttctcaa atatcctttt
    21721 acataatcac aagtagcaac gatttcttca atttgacgat cgaatcgata agcttttgca
    21781 aggtatgtcg ctgtatcatc acgctcattt ttaggaggtt tagtcaagtc ttcttcatca
    21841 tacttatcaa tatagttatg caaagctaaa taatctacat tctcataagc ttcttctaat
    21901 gcgatacgat cccattcagg gtacgatggt aaacgtggcg tagagcttcc aactaagatt
    21961 gtttcaattg aatcatccac taacttcatg acttttgagg cttcatttgc taacctacca
    22021 tattcataag cactcttagc ccccacttgc catggaccgt ctagctcatt ccctaaacac
    22081 cataatttaa cgccaaaagg ctttttttgc ccatttttta ttcttaaatc actccagaag
    22141 gttccttttg gaaaattaca atattctact aaattttttg cttcatcaat tccttttgtt
    22201 cctaaattca ccgtgaatat cggtttcgct tgtacatgac tgatccattt aaaaaattcg
    22261 tggagtccaa aagaatttgg ttctatacct cgccatgcta aatcaatttt ttttggtcgt
    22321 tgttctttcc tacctacagt atccacccaa tcataaccag atgtaaagtt tcctccagga
    22381 tagcgaatga cacctaattc taattccttt acataagaga ggacatcttg tctaaacccg
    22441 tcaccatcag ctgtttcatg gcccggttca taaatccctg tatagacgac acttcccata
    22501 tgctcaacaa atgagccaaa cagccgagaa ctgatctctc ctaccgtaaa atcctctctg
    22561 atttttactt tcacttcttc gtccaacagc tttccctacc tttcatttcc tatagtcaag
    22621 ataatagata caagtttcca tacgccacca gcaaagataa aaataaaagg agggaaaaga
    22681 aatatgagca gtacaaatcc taataacaat acgcaacaaa gaatatttct caaaaaatca
    22741 aaaaatactt tccatgcact ttgttcaaaa atttgtaaaa atgtgatatc tttgttttca
    22801 gaaatcacat atatccagga taaaagaaac atggaataaa taagtaaaac tacatatcca
    22861 ctaattgaaa gtacgattgt ctgttcttct aataattgat taacaagaaa ataaataatg
    22921 atcgttaaca gactaaggaa caagttctta ccaaaatgtt gctttattcc ttgaaagaaa
    22981 aaataaatga tatttcctga tccctcacct ttccattgcg ccattacata aaaaacagca
    23041 catgtagcag gcacgatagt aataacaggc aaacacacga ttacccagag aatacctaat
    23101 aagatgtaat cagaaaccac aatcaactgt ccataaagtt tagtctcaac tattttcatc
    23161 ttcctcactc tttcattcca gacatagctg ttccttgaac aaaatatttc tgtgcaaaaa
    23221 tataaaccac tagtaatggc agcattgaaa taaccgttcc agccattaca ggtccataaa
    23281 aagaaatgtt ctgccctgta aataaagcta accctgctgg taaagttctc atttttgaac
    23341 tacttgtcaa tatcaatgga taaagcaagt cattccaact attcatcagc gtgaaaatcc
    23401 ctaatgataa aagagtaggt ttgctcaatg gcaacatgat tttcaaaaaa atattaaact
    23461 cacttaatcc atcaatgcgt gctgcctctt ccaaagaatc tggtaaagta ataaaaaagg
    23521 aacgcatcat gaagatacca aatgcagttg tcatacgagg aatgatcaaa cctgcataag
    23581 tatcaagcat gccaagcaaa ttgacttcaa taaatagagg aatcatgaag acttggaatg
    23641 ggatcatcat tgtcagcaaa acgaaataga acaaaactga ttttcctttg aaacgcatac
    23701 gagcaaatgc ataccccgca agagaatcaa agaatacaga agtgatcact gtccctccag
    23761 caaaaatcac tgtatttttg atgtaatcta ataaagggat cgttgtccaa accttaatat
    23821 agttatctag ggtatagcta tctgcaaata ttctaggcgg aaatgagata atgtcttttt
    23881 cgtgtttaaa agaagaaata atcagccaca aaaaaggaaa cgcaataacc aacaatataa
    23941 ctagcatact aatcgttcga atgatttttt taccactaac tgcttttcga ctattcacag
    24001 taactgtaat cgagctttct ggtgccatac aggtttccct cctatttcat ttgtttttct
    24061 ttccgtgaca tgtacacatt agtggagata gctatagttg caacaatgat aaacaaaacc
    24121 gaagacagtg ctgatgcata gcccaattca taaggtgctg taaatcctcg actgtaaata
    24181 tattgaacag ctgtttctgt cttaaattgt gggccaccag cggttgcaac atatacttgg
    24241 tcaaacactt gcatcgaacc aatcagattc gttaaaatac aaaaacctaa ggagggaacg
    24301 atctgaggta gcgtaatgtt aaaaaactgc tgtcgatttg ttgcaccatc catttgagca
    24361 gattcataca aagagggaga gattccctga atagcagtca agagaatcgt catagtaaca
    24421 ccaaaattct tccaaacagt catgatggct accgtcggca tagcaagggt tggatcgcga
    24481 aaaaattgag ggatcggcaa gccgacttgt gaaaacaagt aaggaatcgc ccctacattc
    24541 ggatcaagca acatagaaaa aataatcgca attgacgtca atgaacaaat aactggaatg
    24601 taaaatgtcg aacgacaaaa acgattgaat ctggtatttt tagataatgc tactgctgct
    24661 aataaaccaa cgataatttg tgttggcgtt tcgagtacgg tgaaatataa agaatgaatc
    24721 aacgaattaa ctgctcgttc atcactaaat atacgtgtga aattttcaaa acttacaaaa
    24781 tttcttgatg taaagaaaat attcaaatct gtaaaactaa tagcaaatgt tcctaaaagc
    24841 ggtatgacag taaataataa taaaactaaa aaagatggag ttaaaaacaa atacgcagca
    24901 cgatcaggac gattccaata tttggtgaat ccgttcatat agtccacctc atctttcatt
    24961 ttgataaaat atacaatctt ggtttaaacg aatctgaata agatatccga acaatcgctg
    25021 tgatttttgc aataacacct atctgcaaat actaggtcga tcattcagat atctgtatct
    25081 tgccaacagt ctatcctgta taaagttctg tactattttt gcagtaattg attgatggca
    25141 tcatctgcat cgttcatgag tgtctcagga tcttctcctg ctaataattt ttcaatcagt
    25201 ggattgatga tatcgttatt gatcgcagag atttgggtaa aacctggtaa atatggctct
    25261 gcatagtcca tttgtttcga taattcagat acaataggat cattttttac ttcttcatct
    25321 tttgctactg aatccaagta ggcaggaaaa ccattttcga tactccattt tttaccaatt
    25381 tcagttgtat tccaatattt caaaaactca tagacagctt cttttttatt attatctgta
    25441 cttgccggaa tggcatatcc tacgccatct aaaatagctg tttttttgtc tgaatcactc
    25501 ccttgtggta aggtagtcac attataatca atctcgtttg ctttcaatcc gttatttaac
    25561 catggcccat tgatttcaat ggctagttga ccagcattca ttaaattgtc catttcggcg
    25621 ccagaaatcg attctggacc agtcttgtct acatggatca ttttttggat cgcttttaac
    25681 gttttaaggt tctcaggaga cgcaaattca gacttagtat aatcatcgtt cactaattta
    25741 ccgccatttg ctaacatcca gttatataac ggtgcagttc catccttatt gaagacaaaa
    25801 cctgatacat ttttactact atcagttaat tttggtgcca tttctgtcaa ttcttcccaa
    25861 gtagtaggtg gttgttcagt atctaatcca gcttgtttaa acaaatcatt attccaatac
    25921 atatacatgc cttgtacctg catggggaca aaatactgtt taccttctac ttcacctaat
    25981 tcaatagccg tttctttaaa atcagattta tctactccat catattccca gaaatcgtct
    26041 aatggttgta ccgctccgtt ttctacatac tgtgcaaaat ctggataatt taatgcaata
    26101 aagtcaggtg cttttttaga agaaatcgct gtaggaagtt tttcattcaa attggcccaa
    26161 gtcatgatat ccatttcaat tttgatgttt ttatcatttg ttttattaaa ttcattaacg
    26221 atttcttgca atatttcacc atcagatgca gtaaacccat tccaaaaagt caaagtcact
    26281 tctttatcag aatcagattc tgctgaactt ccgccaccgc aagctcctaa aatacctgtt
    26341 gcagctacca acaaagagcc aattaaccat tttttacctt tcattttttg ttcctccttc
    26401 atctgataaa cgacatctga ccacattcca agatagcggt ttcaataaac aattgatttt
    26461 cccatcttca gcttttacat ttgttgaatg acttggtttt acttgttcac ttttaggaag
    26521 attagttgct tttgtatcaa atccactcat ttcagaaaaa tcaatcactc cctctaatga
    26581 taattcagac aagtgaacag ttagattcat ttcttcttct ccacggttaa ctgcaaatat
    26641 gacaagttct ttgtcattta ttacggctat actttctaaa tacggcactt cttcaaaatc
    26701 ttccgtcgca tagtttgctg aacgaatttg tgggcttaac acctctcctt gtccatacac
    26761 agcagcttgc ataaatggat aatagatcgt ctgtctccaa gcttctccgt ttgtttctgt
    26821 cctgattggt gcaataacat ttaccaattg agcaagacaa gcaatcttta ctctatctgc
    26881 atgtttcaat aaagtgatta atagacagcc taatagtaat gcatcttcaa aattatagtt
    26941 atcttctagt aaaggaggag caatctgcca aggcgctgct tgctcatctt gttccgctga
    27001 atgataccaa atattccatt catcaaagga caggttgatc tgcttcttac tatgtttctt
    27061 cgccttgact gtatcgcaca tcgctgtcac ttcagaaatg aaccgatcca tgtctaagga
    27121 acgtgcaaga taatgagaaa gatcattttt ttggttgcca taatattgat gcagagacaa
    27181 ataatctatt tgatcgtacg cttgatcaag aactgttaac tcccaatcac caaatgtagg
    27241 catttgccga ttcgaacttc cgcataaaac cacctcaatt gaatcatcta cgagtttcat
    27301 cgccttagcc gtttcctctg ctaaccgtcc atattcttcc gctgttttat gtccaatctg
    27361 ccaaggaccg tccatttcat tccctaaaca ccatgtctta attccaaaag ggctctcttg
    27421 accattcgaa cgccttaaat cactccaata agttccttta ggaaaattac aatattcgac
    27481 taaattacga gctgcatcta ctccacgagt acccagattg acagccatat tgatttcggc
    27541 ccccacatgc tgacaccagt tataaaattc atgaatccca acttcattcg tttcaattgt
    27601 ccgccaagct aaatccaacc ttctaggtct atttgctatg ggcccaatac tgtcttccca
    27661 acgaaatcct gacacaaaat ttccaccagg atatctaatc atgggaatgt tcaattcttt
    27721 taccaagtga atgacgtctt ggcgaaatcc acttttatta gctgatggat gatctggctg
    27781 ataaatccct tcatatactg ctcgtcccat atgttcaata aatgaactgt acaaccgcgg
    27841 atcaactttg cctacacgct tgacactact aatcaacatt gtggcttcca taactgacct
    27901 cctttaattt atacatgaat aatacacctc gttgaaagcg ttgtcaataa tataaatgtt
    27961 aaacttactt attttttatc gattttaatt aaccaaaata ttaataatga ttaaaacaaa
    28021 taatttaata taacttttat taacaaatat gttaatatat aagaaaaacc ttttaagagg
    28081 tgatatatat gcaactacaa ataaacgaag aatccttacc ggtatatgaa gcattagcta
    28141 gtaaaacaag gatcaagatc atccagctac tttccaaaaa aaagatgaat gtcaaagatt
    28201 tggcaaaaga acttggagtg agcagtgcta tcacgacgat gcacgtgaaa aagctagagg
    28261 aagcaaacat catcaaaaca gaaaaagtag gacaacaaaa aatttcgagc cttcgtgtcg
    28321 ataaaatcga tatcagtttt ccagaaaaaa tattcaatgc ttttgatacg aaagaaacat
    28381 cgatacctat tggtcactat acaaattatg caattgaacc aacatgcggt ttagctacga
    28441 tccatgattt tatcgggaaa gtggatgaac cacgctattt tatggatcct cgaaggatgg
    28501 atgcccgcat tctctggttt accagcggat ttgtcgagta tcaggcacct aattttttaa
    28561 atacagagga tacattggag atgttggaag tttctgtgga aatttcttct gaatttcctt
    28621 tttcaaatga caattggcct tcagatatca ctttcagcct aaatggtgtg gagctaggaa
    28681 catggacgag ccctggagat tttgctgata tccgcggtaa atatacgcct gattggtatc
    28741 cagataatct taatcaatac ggcttgctga agacgatccg aattaccaaa cacttgacga
    28801 atatgaatgg agaacccttg tcaaacatca cgatcaacga catccctaaa gagcaagaca
    28861 cttggcattt gcgaatcgaa gtgaaagacg atgccaaaca tgtggggggc tgtactttat
    28921 ttggtaaagg attcggtaat tacgatcagg atatcaaatt aaaagtttac tacagctgat
    28981 atttttcttt tctattttat aaaacaaaaa cagccaatcc ctatgaaggg acggctgttt
    29041 ttgctttatt gttatttcca gaaatcatcc aaaacggaaa ttggcaaatg tcgtttatgt
    29101 tgtgtcttgt tccaccatgc ttcgattttt tcttgtgctt gagcgggaac ttcttttcct
    29161 tctagataat catcaatttc attatatgtg acacctagtg cgacttcatc tgcaatcatt
    29221 ggtttcccat cttcaagatc tgcagtcgga atttttgtgt ataatttttc cggtgcattc
    29281 aatgcttgaa gcaattgttt cccttgtcgt ttgtccaaac ggaataatgg caaaatgtcg
    29341 gctccaccat caccaaattt cgtgaagaat ccagtaatgt tttctgcagc atgatctgtc
    29401 cctaatacgg ctcctgctct ttctccagct acggcatatt gcgtaatcat acgttgacgt
    29461 gctttgatat ttcctttgtt aaaatcgctg attcccacac ctgcttcgct taatacttgt
    29521 acttgtgcat caacagctgg tttgatattt actcgcagac taacatcggg ctggataaag
    29581 tcaagagcag cttttgcatc ttcttcatct gcttgttcac cataaggaag acgaacagcg
    29641 ataaattgat agttttcatc ttttgtttct tcacgcattt cttccatcgt tagttgcgcc
    29701 aaacggcctg ctaaagtaga atcttggccg ccgctgatac ctagtacaaa agttttaaga
    29761 aacggatatt ttttcaaata tgctttcata aagtcaatac ttttacgtat ttcttctttt
    29821 ggatcaattg ttggtttgac acctaattca ttgataattt ctgtctgcag gctcatttat
    29881 tctcctccta tgcttctgta tgaagttctg ctacgctttt tttcattcgt tccatgatag
    29941 ccattttatg gttccagcat tcagtagaca gatcgactgg gtatttttgc ggattcaagt
    30001 ctcgtttata ctcttcccat agtgaatcta gattttcttt tgtatattct ttgatttcgt
    30061 ttagtgcagg taattcgtaa actctttttc cttcgataaa gatatcttgt aaaactgggc
    30121 gagctgtaaa gtctcgaaca gttttattga taaacgtatg cactggatgg aacatgaaga
    30181 tagcttcttc ttctcgaggg tcttcatccc ataatgtcac gtagtctcct tcagatttcc
    30241 catcaaaatt tcgagtgatg cgccacactt gttttttccc tggagtagtt actttttctg
    30301 cattgcttga taacttgatc gtatccatca tttttccttc atcatcttcg atcgatacta
    30361 gcttgaatac tgcaccaagg gctggctgat cataggctgt gatcaatttt gtcccaacac
    30421 cccatacatc aattttagct ttttgcatct ttaaattcaa aatcgttgct tcatccaagt
    30481 cattcgaagc atagattttt gcttccgtaa atccggctgc atctaattgt tcccgaacac
    30541 gcttagatat ataggccata tctccactgt cgatgcgtac gccttggaag ttgattttgt
    30601 cacctaattc tttcgccacg cgaatcgcac ttggcacacc tgatttcaac gtatcataag
    30661 tgtcgactaa gaacacgcag tctttatggg ttttagcgta ggccataaat gcttcataat
    30721 catttccata agattggact aacgaatgag catgggtccc gctagctggt atcccaaata
    30781 tcttcccagc acgtacattg cttgttgcat ctgctccgcc gatatatgcc gctctagttc
    30841 cccagactgc tgcatccagt tcttgtgccc gtctagttcc aaattccaat agtggatctt
    30901 ctccgatgac agatttgata cgagctgctt ttgtcgcgat caacgtttgg aaattgacca
    30961 tattcaacag tgctgtttct actaattggc agtgcgctaa aggcccttcc acttggatta
    31021 atggttcatt tgcaaaaact agttctcctt cacgagcaga acgaactgtt gctttaaatt
    31081 caaaattttg taaatactcc aaaaaacctt caggatagac ttctaatcca cgcaagtaag
    31141 caatatcgga atcattgaac gtcagattct ctaaataatt gactaaccgt tccaatcctg
    31201 caaaaaccgc gtatccgtgg ttaaaaggca tttctcgaaa gtaacattca aaaacagcat
    31261 gtaaatcagc tcgacctaat tcccagtatg tctgcatcat attgatttga tatagatccg
    31321 tatgcagcgt caaactgtcg tctgggtaag tattattcat cttgtattac tcctcttggc
    31381 aagttttcat ttcctaccca ttataacaaa aaaaattaat aggaaaagaa atcttccatt
    31441 ttttctgaaa aagcacatgt tttacggata tttcttgcta aaaatgaact ccatctgcta
    31501 aaactatcct ttcttattgg tatttaacct aaacgagaaa gaatacttat tttattcaat
    31561 gtatccgaga cacgaagaaa ttagcgtttt ctatttttct tacttgataa aataagtaga
    31621 ttttcctact acaatcgtag ccgttaagat accgatgatt gaacaaatat aaccaaatgt
    31681 ctctacaaca taatcaatgg caaaagtttt tgaagcaata atacgtcttt ccttttttgc
    31741 ttcttatccc caaagaaacg gatataactt attatgtatt gaattttttt ggaaaggcga
    31801 attatgacaa gatatacctt gcgttgaaaa aactcgcgga aaaaatatca cacgttttta
    31861 aaaagataca aagtaagaaa gcagctgtca atagaatgga aacaaaaatg gcgagacatc
    31921 aatcagtctc gccttgtttt ttattgtata cattagatat ggagcaggtt accataaaga
    31981 tgattattag tcgttattaa atagaatcct tcgtattttt ttgttctatc actacaatat
    32041 ctttatttgg acgtttgaat tgtattccgg cacgttctag ctcctgtttc actcctacat
    32101 ggactttgac atcttctcgt gtcattttta aaacgtgatg aatcgcatag tcgatttctt
    32161 gccttgtgat ttttttcttc gtattgatca tcacgacttg ctttttatca tatgtgtcta
    32221 ccaatagcag ttgtgttcga tctaacgaaa ataatttgta ataattaata gccgtattcc
    32281 caaaaaagaa ttccactact ttaggataaa atgtcttaat atttaaatta ctattcacag
    32341 gtgtttcgat tagcttcatc tcattcctct tttctatata gtcgatttag atccaatctt
    32401 aagttatgtt accatctttc ctagcattaa ggaatcggtt acaattgaac ctttaaagac
    32461 aaaaggattt accttttatc acttaatagt ataacataat ttcgtgagaa aaaaatacaa
    32521 ttttttcttg accatctcgt tacgtaaagg attatgctta catttgtcag gaggaaaaat
    32581 aatggagtac acaataaaga aaatgtcaga gatatcagga gtcagtccga gaaccttgcg
    32641 cttttatgat gagattggac tgctaaaacc agctaggatc aattcttcag gttatcggat
    32701 ttatggcaaa aaagaagtcg atcgtctgca acacatctta ttttatcgaa caatggcatt
    32761 caagttggat gatatccaag aggtcttaga caatccatct tttgaccacc agaaagcttt
    32821 aatcaagcat cagcaaatgt tgctggaaaa acgggcacaa atcgataccc tcttgacaac
    32881 tgtccaacag acacttgata tgtacgaagg aggaagaaaa atgagtgaca aagaaaaatt
    32941 tgaagggttt aaacaacaaa agttgaaaga aaatgaagaa tcctatggac aagagattcg
    33001 acaaaaatac ggaaaaaaaa aggttacagc atccaatgaa aaatggatga atatggataa
    33061 agaaacgtat gaagaaatgc aaactgttga aaagcagatg ttatttgatc tcactcttta
    33121 cttaaaagaa ccagaagatg aaagcttagc agaccgtatc ttccaagctc ataagaagtg
    33181 gttctcttac agctggcctg aatatcagcc aaaagcgcat aaaggactag gaatgatgta
    33241 cgaagccgat gaacggttca ctgcatatta tgacgagcga agtggtcatg gtgcagcaaa
    33301 agctttaaat gaaattatcc aaaaaaaggc gtaatctttt acatgatcca acaaaaaagt
    33361 acacgtaaaa tgacctaata acaaaacagc agacacccaa gttagatttt tatgctaact
    33421 tttggtgtct gctccattct ttcacaagtt ttttcatcct actttaaata tattcatcgt
    33481 tgaataaacg tataaggtat tttcacttta tccttttttt ctgtaagaaa caattgaaat
    33541 gccatttctc cgcaagcttc cagatggtgg tcgatggttg ggaaaccaag aagctcgctg
    33601 atcagcaaat tatcgcgtcc aatcaccact ggtgtcttat cttgcagata gctttgcaag
    33661 atgcctgctg caaccatatc cgaatttgta aagacaccat caactccaag ctctttaaaa
    33721 aagaagcctg cttgttttcc tttctctgca tctatacaat cccaaaaaac aagtgattca
    33781 tcaaaagatg gaaaaagttg atgacatagc tgcaaagtga tttttgagtt ataacttagc
    33841 ctgccacttc gccccaacgt gatgcccaat tgctttatac cttgctgctt caaataagta
    33901 agaccttctg taattgattg ttctcgatca ataaagacac agcttgcctg ttttcccttg
    33961 atttcttcac aaaaaactag aggtccatat ttttgatatg ccaataaatc atctagtgta
    34021 ttggcacgag acgtaatgat caatccatcg aaagctttag ctgcaaattc ttcaagatac
    34081 cttcgctctt tttctttatg atagcccgtc ggtaaaagtg tcactttgta atcataatca
    34141 aacgctgctt caatgatccc actgatcaac tgatcaaaat acggatgatt ggtataaggc
    34201 agaatcactc caatgctttt cgtttttcca taacttaact gtctggcatt tgcattaggg
    34261 atataatcga cttctttcat gaccgcaagt atttctttcc ttttttcctc atctacatat
    34321 ggatgtccat tgattacacg tgaaatagta gaaactgaat aacctgtgag ctttgcgata
    34381 tctcgaatgt ttgccactgc tgcttcgcca cctatacaaa aagattttct tgtaaatagt
    34441 ctaccacagc tggaccgcat tcaaaaaact gatacatttt tccttcatgc gaaaaactga
    34501 tccgctgccc gccccaatat atatcttttg tcaaattttc gatttcattc attggtattt
    34561 cttttactat attcctattc aacccttgaa aactgtacaa cgttaatacg gatcccttga
    34621 actcgacaaa cgcataaaaa taattgttcg ttgtgccatc tgttatctct acataagtat
    34681 tcattgcaag ccctcctttt gatactttga gtatagtgta tgaaacgcgt ctcatagcaa
    34741 ggagtttgtt ttgccaaaga aaagttttat tcctctttca ttattaccaa agtctcttat
    34801 tttaaattga atacattata atgatactgt aaatatatct ttattattag tgaatg
//
LOCUS       DAFLWZ010000021        34765 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000021 DAFLWZ010000000
VERSION     DAFLWZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.021"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(227..1114)
                     /locus_tag="L1V38_001123"
     CDS             complement(227..1114)
                     /locus_tag="L1V38_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1315684.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="L1V38_001124"
     CDS             complement(1111..1980)
                     /locus_tag="L1V38_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1315685.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="L1V38_001125"
     CDS             complement(2117..3403)
                     /locus_tag="L1V38_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1315686.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="L1V38_001126"
     CDS             3676..4254
                     /locus_tag="L1V38_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1315687.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="L1V38_001127"
     CDS             4254..5183
                     /locus_tag="L1V38_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1315688.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="L1V38_001128"
     CDS             5180..6916
                     /locus_tag="L1V38_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1315689.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1V38_001129"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1V38_001129"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBN1315690.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="L1V38_001130"
     CDS             complement(7812..8321)
                     /locus_tag="L1V38_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBN1315691.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1V38_001131"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1V38_001131"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBN1315692.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="L1V38_001132"
     CDS             complement(9622..10713)
                     /locus_tag="L1V38_001132"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBN1315693.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1V38_001133"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1V38_001133"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBN1315694.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1V38_001134"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1V38_001134"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBN1315695.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1V38_001135"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1V38_001135"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBN1315696.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="L1V38_001136"
     CDS             complement(14676..15650)
                     /locus_tag="L1V38_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBN1315697.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="L1V38_001137"
     CDS             complement(15631..17514)
                     /locus_tag="L1V38_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBN1315698.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="L1V38_001138"
     CDS             complement(17532..19757)
                     /locus_tag="L1V38_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1315699.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="L1V38_001139"
     CDS             19872..20906
                     /locus_tag="L1V38_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1315700.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="L1V38_001140"
     CDS             complement(20973..21986)
                     /locus_tag="L1V38_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1315701.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="L1V38_001141"
     CDS             complement(22064..22252)
                     /locus_tag="L1V38_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBN1315702.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="L1V38_001142"
     CDS             complement(22692..22820)
                     /locus_tag="L1V38_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1315703.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="L1V38_001143"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="L1V38_001143"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1315704.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="L1V38_001144"
     CDS             complement(24307..25362)
                     /locus_tag="L1V38_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1315705.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="L1V38_001145"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="L1V38_001145"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBN1315706.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="L1V38_001146"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="L1V38_001146"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBN1315707.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="L1V38_001147"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="L1V38_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBN1315708.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="L1V38_001148"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="L1V38_001148"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBN1315709.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="L1V38_001149"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="L1V38_001149"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBN1315710.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="L1V38_001150"
     CDS             33124..34683
                     /locus_tag="L1V38_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBN1315711.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9514 a         7494 c         6334 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctg
//
LOCUS       DAFLWZ010000022        34739 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000022 DAFLWZ010000000
VERSION     DAFLWZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.022"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            669..1358
                     /locus_tag="L1V38_001151"
     CDS             669..1358
                     /locus_tag="L1V38_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315712.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1345..2553
                     /locus_tag="L1V38_001152"
     CDS             1345..2553
                     /locus_tag="L1V38_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1315713.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2847..4118
                     /gene="serS"
                     /locus_tag="L1V38_001153"
     CDS             2847..4118
                     /gene="serS"
                     /locus_tag="L1V38_001153"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBN1315714.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4667..6151)
                     /gene="guaB"
                     /locus_tag="L1V38_001154"
     CDS             complement(4667..6151)
                     /gene="guaB"
                     /locus_tag="L1V38_001154"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBN1315715.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6656..7351)
                     /locus_tag="L1V38_001155"
     CDS             complement(6656..7351)
                     /locus_tag="L1V38_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBN1315716.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7441..8541)
                     /gene="ychF"
                     /locus_tag="L1V38_001156"
     CDS             complement(7441..8541)
                     /gene="ychF"
                     /locus_tag="L1V38_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBN1315717.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8550..8741)
                     /locus_tag="L1V38_001157"
     CDS             complement(8550..8741)
                     /locus_tag="L1V38_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBN1315718.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8762..9652)
                     /locus_tag="L1V38_001158"
     CDS             complement(8762..9652)
                     /locus_tag="L1V38_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBN1315719.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9639..10406)
                     /locus_tag="L1V38_001159"
     CDS             complement(9639..10406)
                     /locus_tag="L1V38_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1315720.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10418..11131)
                     /gene="rsmG"
                     /locus_tag="L1V38_001160"
     CDS             complement(10418..11131)
                     /gene="rsmG"
                     /locus_tag="L1V38_001160"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBN1315721.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11363..13264)
                     /gene="mnmG"
                     /locus_tag="L1V38_001161"
     CDS             complement(11363..13264)
                     /gene="mnmG"
                     /locus_tag="L1V38_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBN1315722.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13281..14678)
                     /gene="mnmE"
                     /locus_tag="L1V38_001162"
     CDS             complement(13281..14678)
                     /gene="mnmE"
                     /locus_tag="L1V38_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBN1315723.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14977..15360
                     /locus_tag="L1V38_001163"
     CDS             14977..15360
                     /locus_tag="L1V38_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315724.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15528..16286)
                     /locus_tag="L1V38_001164"
     CDS             complement(15528..16286)
                     /locus_tag="L1V38_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBN1315725.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16304..17122)
                     /locus_tag="L1V38_001165"
     CDS             complement(16304..17122)
                     /locus_tag="L1V38_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1315726.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17119..17475)
                     /gene="rnpA"
                     /locus_tag="L1V38_001166"
     CDS             complement(17119..17475)
                     /gene="rnpA"
                     /locus_tag="L1V38_001166"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBN1315727.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17593..17727)
                     /gene="rpmH"
                     /locus_tag="L1V38_001167"
     CDS             complement(17593..17727)
                     /gene="rpmH"
                     /locus_tag="L1V38_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBN1315728.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18250..19584
                     /gene="dnaA"
                     /locus_tag="L1V38_001168"
     CDS             18250..19584
                     /gene="dnaA"
                     /locus_tag="L1V38_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBN1315729.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19782..20912
                     /gene="dnaN"
                     /locus_tag="L1V38_001169"
     CDS             19782..20912
                     /gene="dnaN"
                     /locus_tag="L1V38_001169"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBN1315730.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21141..21383
                     /gene="yaaA"
                     /locus_tag="L1V38_001170"
     CDS             21141..21383
                     /gene="yaaA"
                     /locus_tag="L1V38_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBN1315731.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21370..22494
                     /gene="recF"
                     /locus_tag="L1V38_001171"
     CDS             21370..22494
                     /gene="recF"
                     /locus_tag="L1V38_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBN1315732.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22491..24437
                     /gene="gyrB"
                     /locus_tag="L1V38_001172"
     CDS             22491..24437
                     /gene="gyrB"
                     /locus_tag="L1V38_001172"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBN1315733.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24457..26928
                     /gene="gyrA"
                     /locus_tag="L1V38_001173"
     CDS             24457..26928
                     /gene="gyrA"
                     /locus_tag="L1V38_001173"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBN1315734.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27164..27463
                     /locus_tag="L1V38_001174"
     CDS             27164..27463
                     /locus_tag="L1V38_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBN1315735.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27513..28025
                     /gene="ssb"
                     /locus_tag="L1V38_001175"
     CDS             27513..28025
                     /gene="ssb"
                     /locus_tag="L1V38_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1315736.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28051..28287
                     /locus_tag="L1V38_001176"
     CDS             28051..28287
                     /locus_tag="L1V38_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBN1315737.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28430..30403
                     /locus_tag="L1V38_001177"
     CDS             28430..30403
                     /locus_tag="L1V38_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBN1315738.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30409..30861
                     /gene="rplI"
                     /locus_tag="L1V38_001178"
     CDS             30409..30861
                     /gene="rplI"
                     /locus_tag="L1V38_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBN1315739.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31135..32502
                     /gene="dnaB"
                     /locus_tag="L1V38_001179"
     CDS             31135..32502
                     /gene="dnaB"
                     /locus_tag="L1V38_001179"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBN1315740.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33282..34574
                     /locus_tag="L1V38_001180"
     CDS             33282..34574
                     /locus_tag="L1V38_001180"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBN1315741.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10582 a         6750 c         6866 g        10541 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcagg agtgtttccc gattcgtttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa gtaattgtca actctttttt aaaagttttt tcgatttcgt
      181 ttttcgaaat cttccagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac
      241 ttttttgaag tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca
      301 gttatcttat catgtcattt ccaacatgtc aacaacttat tttttattat ttaataagtt
      361 attggtgttc ttttgaacaa ataataatat atcaacatca catgtgaaag tcaataagaa
      421 aatgcttatt tatcaacatt tctagcttac atgatcattg gttagttctg gtcctttttc
      481 gttcgtcttt ataactccga gagacgtaaa atccttttgt tttcagttta atgttcatgt
      541 tcttgtctta ttcacaccaa ctagatgtct caccttctaa aattttcctt aacaaagtgc
      601 tgcttttatc tatttctgct tttttttgct agaataatag taacaatatg actctggagg
      661 atttatttat gaaaattttg attgctgacg atgataaaga aatcgttgaa ttattaagta
      721 tctatgttca caatgagggg tatgaagcag taaaggctta tgatgggaaa gaagcattat
      781 ctaaaatcag aacaatccct gatattgaat tacttatttt agatatcatg atgcctgaga
      841 tggatgggat gcaagtagtg aaagagctac gaaaagaatc ccaaatacca atcattatgc
      901 tgacagcaaa aactactgat atggataaga tcaaaggact ggtcgctggt gcagatgatt
      961 atgtgaccaa gccatttaat ccgttagaag taatggctag agtaaagtct ttattacggc
     1021 gtacaaaaat gcagattgcc ccagatcagc ctgatgtatt agaagtaaat gcattaatca
     1081 tcaataaaga ctctcatgaa gttaaaacaa tcgatgggaa agaaatccag ttaacagctt
     1141 tggaattcgg tatcctctac ttgcttgcta gtcatcctaa tcgagtattt agcgcggatg
     1201 aaatttttga gcgtgtttgg aaacaagaaa gtattgtctc tgctaaaact gtcatggttc
     1261 acgttagtca tttaagagat aagattgaag aagcaactgg tggtgaaaaa gtcattcaaa
     1321 ccgtttgggg agtgggctat aaaattgacg caagatagta aacgagcaac tgaaaaacgc
     1381 cgtcggatca atttgacttc aaaagaaatc agcgaattgt tagcggaagg aatcatcacg
     1441 attatccttt tgcttctatt aaatgtttct attctggttg ttatcagttc ggtgatcaac
     1501 agttcacctt ctttgacgaa tgcgatttgg gattcaaaga atatttttgc agaacgattg
     1561 aacactgatt tgttctggaa cggccggaat tttattattc cctttttctt tctattagat
     1621 attggtgttt tgtattggcg cttgattcga agatatcgcc aaatgcaatt gcggcatatc
     1681 atcagcgaac ttcactacat cgcaaacgga aattatgatc atcgtatccc ttttgaactg
     1741 agtggtgact taagccgagt ggtaacaagt atcaatggat tggtggatag taccgtagca
     1801 gcgattgaag acgaacgtaa aatcgaaaaa tcaaaagatg aattgatcac gaatgtcagt
     1861 catgatatcc gtaccccact cacgtccatc attggatacc taggactgat agaagatggc
     1921 cagtatcact cagaagaaga tcttttaaag tatacgcata ctgcttatat caaagcaaag
     1981 cagatgaaat ctttagtgga cgacttattt gaatacacta aggtacgcca gcctgctgtc
     2041 ccggtgaatt tttctgcctt tgacatgatc cagttgatcg aacagttagc agctgatttt
     2101 gagttggaag cttctaaaaa aaatatccaa atacttgttc aatcaaaagt agactccctt
     2161 atcatggatg gcgataccga aaaacttgta cgtgtcttca ataatctttt gacgaatgcg
     2221 ttgaaatacg gaaaaggagc aacgaagatc gtaatcgaag tagaacgtat cggttcagaa
     2281 gttgttgcaa cagtcaaaaa taacggagca atgatcccac aacaggcaat cgataatcta
     2341 ttcgaccgtt tttatcgtgt agaagaatct cgttcacaag caactggagg aactggactt
     2401 ggtttagcaa tcgctcaaag cattgtggct ttgcacggcg gatacattta tgcaaaatca
     2461 gataagcaat ggacttcttt catcatgcac cttccaatca agaaaaatga aaaattacct
     2521 attgatacac aggaagttat tgacgaaagc tgaaatattc gctattctta ttacaattat
     2581 tagaataaat gaaaaacaca gaacccagta cactttattc tttttcagag agctgatggc
     2641 aggtgtaaat cagcaaagga taatttggaa gttccagttc gtttacgtgc cctttcgaaa
     2701 taagaaaggt cggttcaaca gccgttatgt gttcaacaag tgcagctgac gctgaacttg
     2761 ggtggtaccg cgaatttcag actgattcgt cccaagaata atgggatgga tcagtctttt
     2821 tttattttca aaaaggagga aatcatatgt tagatgtaaa aatgatgcga caaaatattg
     2881 aagaagtaca agaaaaattg atgactcggg gcgtaaaaaa agaaacatta gctgaattca
     2941 tggaactaga tgaaaatcgt cgtaagctac tagtcaaaag tgaagaatta aaaaaatatc
     3001 gaaatgatgt ttctgctgag atcgcccaat tgaagcgtgc aaaagaagat gcttctgcta
     3061 aaatcgctga aatgaaagaa gtcggtggca acatcaaagc attggatact gaaattgctg
     3121 aagtggatga aaaattgaaa caaattgcaa ctactttgcc aaaccttccc catgattctg
     3181 tgccagttgg aacagatgaa gaggacaatg tagaaatccg tcgttggagc gaaccacgta
     3241 catttgcttt tgaaccaaaa ccacactggg aaattgcaga aaatcttgat attttagatt
     3301 ttgaacgtgg cgcaaaagta gccggtagcc gttttgtcta ttacaaagga ttaggtgctc
     3361 gattagaacg tgctgtctac aacttcatgc ttgatcagca tatttacgaa cacggctata
     3421 ctgaaatgat cactccttat atcgtcaaca gtaaagcgat gtttggtacg ggacaatttc
     3481 caaaattcaa agaagatgtt ttccaattgg agaatactga tctaacatta atcccaacag
     3541 ctgaagtacc attaactaac tattataatg atgaaatttt agatggtgca gatttaccta
     3601 tttatttcac tgcactaagc cctgcttttc gttctgaagc cggaagtgct ggtcgggata
     3661 cacgaggact gattcgtctt caccaattca ataaagtaga aatggtcaaa ttttcggatg
     3721 tagagcattc ttacgaagaa ttggaaaaaa tgacagctga tgcagaagat atcttgaaaa
     3781 aattgcattt gccttatcgt gtgatggcct tatcaactgg agacatgggc ttttctgcag
     3841 ctaaaactta tgacttagaa gtatggatac ctgcacaaga tacttatcgt gaaatcagtt
     3901 cttgttctaa ctgtgaagat ttccaagcac gccgcgcaat gatccgttat cgcgataatg
     3961 atggaaaaat ccactatact catactctga atggttcagg acttgcagtt ggccgtacag
     4021 tagctgccat tttggaaaac taccaaaatg aagatggttc tgtcacagtt ccagaagcgc
     4081 tcgttcctta tatggggaat ctgaaagtta ttaaataaag aggctgtgaa aaagccgctt
     4141 agtttcgagt attaagaaaa attttgtgaa aatggctttc cacatttttg cataaattgg
     4201 acttaatacc gagaaactgg cttttgaaca ccatttatcg agaggttgtg aaatcagcga
     4261 attaacctga gtattagaga aaaaaatgga aaaatagtcc ctcatatttt accgtttgtt
     4321 gaactaatac cgagggtcag ctgattgaac accgtttagt ggagaggtcg taagcctacc
     4381 ccccagctcc tagttacaag gacaaattca aaaaacagct cttcatattt tatgaatgtt
     4441 gtacttgtga ttcggaggtg gcaagggaac actgtttatt caaaaagagg ctgggacaga
     4501 agcgtttaac tccaagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga
     4561 atttcttctt atttccgaag gagttgcttc tacttccgcc gtttatacgt gtttagagcg
     4621 tgagacaaaa gtgttcttta cttttgtccc acgctcttta atgtttttaa gattcaactg
     4681 aatagtttgg tgcttctttt gtgatttgta catcatgagg gtgtgattct tttaatccac
     4741 tgccgctcat ttggataaat tgcgcttcat cacgtaattg ctgtagattg gctgccccaa
     4801 cataacccat tcctgaacgc aaaccgccga tcatttggaa aataatatct gcaacacttc
     4861 ctttataagc aacccgacct tcgattcctt ctggtactaa tttatttgct tcattgacac
     4921 taccttggaa gtaacggtct tttgaacctt tttccatcgc gcctaatgag cccatacctc
     4981 ggtatgtttt gaatcgacgt ccttggaaga tttcgaattc acctggtgat tcatctgtcc
     5041 ctgccaacat acttcctagc atcactgcat gtccgccggc agctaatgct ttgacgatgt
     5101 caccagaata tttgatccct ccgtctgcaa taatcgcttt gccatattga cgagcaactg
     5161 atgctgcatc ataaatagct gtgagctgag gtacacctac accggctacc acacgtgtcg
     5221 tacaaatcga tcctggtccg ataccaactt ttacgacatc tacacctgca tcatataaag
     5281 cttttgtcgc ttcagccgtc gcaacgtttc ctgcaatcaa tgttgcatct gcaaaagttg
     5341 aacggatttc ttgaattttt cggatcacac ctgcactatg tccatgagct gtatcgatga
     5401 tgattgcatc tgcccctgct tctaataaag cattcgcacg ctcaaatgta tcgcttgtta
     5461 caccaacggc tgctgctaca agcaatcgac catgttcatc ttttgctgca tttggaaatt
     5521 cgatcacttt ctcgatgtct ttgatcgtga tcaatccgct taaacgacct tcgttatcta
     5581 cgattggtaa tttttcgatt ttatgttttt gcaaaatctt ttctgcatct tttagagagg
     5641 tacctactgg ggcagtcact aagttgtctt ttgtcatcac atcagcaatc ggcatgtgat
     5701 aatctgttac aaaacgcatg tcgcggtttg taattatccc taccaatttt ctgttttcaa
     5761 gtgtttcaac gattggcaca ccactgatac gatatttgct catcaattct tctgcgtctg
     5821 ctacaagatg ctgtggcgtt aagaagaacg gatcaatgat tacgccactt tcagaacgtt
     5881 tgacttttct tacttcatcc gcttgctggc tgatcgtcat gtttttatgg atcacaccta
     5941 gtccgccttg tcttgccata gcaatggcca tcttgctgtc ggtaacagta tccatacttg
     6001 cactgatgat tggaatattc aacttaatat ttttagctaa ttgtacgctc atatccactt
     6061 cgtttggtaa cacgtgactt tctgctggta tcaataagac atcatcaaaa gtaaatcctt
     6121 ttttcgtgaa ctttgtttcc cagttggaca tttttagtac cactcctcta atttagttta
     6181 tctattaaaa taattgattt tttcatttaa gtcaatgatc tacttggaat caagttagct
     6241 ttctcataga ataccaatat aaagcgttta catctgtgtg tattaaaaga gattgtaaaa
     6301 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga
     6361 attggttggg tttattaccg cagatgcaaa cttttgaaca ccgtttagtg gagaggctgt
     6421 gaaaaagctg cttagtttcg agtagtaaga aaaattttgt gaaaatggct ttccacattt
     6481 ttgcataaat tggacttaat accgagaaac tggcttttga acaccgttta tcgtaaaaag
     6541 ggactgtgac aagacttttg tcacagtccc ttactattat ttaactatgg ataaacaaaa
     6601 tgaggttctt tactacccct agatatctag caaaatagct gatctttttg ctagtttatc
     6661 ttcttgggac ggataaactt ccaataatcc cgtatttttt cttcaagtag taacggattg
     6721 ctaaagcagt tgccccgata atgataacta ctactggatc taatactgga ttgataactg
     6781 gtggcaatag tgttgtcgca gaaaacagta cgacccaaag aagtgtcgtt ccacctagga
     6841 taagcaatgt cttacccatt cctggtttct tgcttcgatc tgctccggga tattcatatt
     6901 gatagatgta tttgtacatc atataaaaga cccagccacc gattgcagaa cctagaacga
     6961 gtgtagaaaa gccataagct ggcgttgttc cacgtgaaaa caatccggta atcgcaatca
     7021 tgatacttaa tagaccaagc aacagcaacg tattatctaa ccacatcaat aaaggggtgg
     7081 atgaattttt tacttctgct ggcttattga tgattgcttc cgttctttca gagactgtcc
     7141 caaacaattg acgggctgtt cttccgcctt tttgttctgc aactaaagta ggcagaatgt
     7201 catgaagggc ttttactttt tcttcttcag acaaattcgc tgcttctaaa gattttttca
     7261 aatcaaaaat gtactgttga tttcttttgg ttaattttgt ttctaaacta ttgttttctt
     7321 ttacgattgc tcgtaattgt tctggttcca ttatctaata gtcctcctta gccgttcctt
     7381 ttctcaacgg tcgtcacaaa agacattcta ccatattcta cagctagttt gatagccctt
     7441 ttacacatta aagcggaata acattacgtc gccgtcttgt acgacataat cttttccttc
     7501 taatcgaaca cgtccagctt cttttgctgc atgcatgttt ccgtaatgat ccaagtcttc
     7561 aaaagagaca gtttctgcac ggataaatcc gcgttcgaaa tctgaatgga tgattcctgc
     7621 tgcttgtggt gctttgattc cttttttgaa tgtccaagca cgtacttctt gttccccagc
     7681 agtaaagtaa gtagctaagc ctaacaaatc ataagcagca cggatcaact gatccaaacc
     7741 tgattcttcg attcctaaag cttctaaaaa ttccgctttg tcttcttcat ctaattctgc
     7801 gatttcttct tctgcacgag cactgaccac gatcacttct gcattttctt ctgcagcaaa
     7861 gttgcgcact tcttgtacat aatgattcgc gtctgcatct gctacgtcat cttctgagac
     7921 attggctaca taaagaattg gttttgtcgt caataaaaat agtgatttaa cgattttttg
     7981 ttcttcttca gtaaattcga tcgttcgggc agattttcct tcttccagta caggtttgat
     8041 tttatccagt acagctagtt ctgccactgc atctttatct ttggttttag caacttttgc
     8101 tacacgagta tagcgtttgt tgatagattc taagtctgct aacactagtt ccaagttgat
     8161 cgtatcaata tcttctagtg gatcaacacg tccttctacg tgagtaatat tatcatcatc
     8221 aaaacagcga acaacgtgac aaatagcgtc tacttggcgg atatggctta agaattgatt
     8281 tcccaaacct tctcctttac ttgcgccttt tacgattcca gcaatatctg taaattcaaa
     8341 agtcgtcgga acagtttttt tcggatgtac aagttctgtt aagcgttgca aacgccagtc
     8401 aggtacttct accatcccta cgttggggtc gatcgtcgca aagggatagt ttgctgcttc
     8461 tgctcctgct tttgtgatcg cattaaacaa agttgatttt cctacgttgg gcaacccaac
     8521 aattccagca gtcaatgcca taaatttatt cactctttct ctgcattttt ttcaattact
     8581 ttttttaatt tcttttcaaa atctcgacgg gtcatcatga cgatatgtcc gcaattcata
     8641 catctgattt tgatatctgc gcccattcga atgacttccc agcgattcgt ctggcaagcg
     8701 tgaggttttt tcatttcaac gatatcgtgc aagtcgtaca taaaaatagc ctcctttttg
     8761 tttattcttc atcaaattga atattcaaga tatcaagaat tcgagtcaaa tctttttgag
     8821 aaagatattc aatctcgatc ttacctttcc catttttttc ttggatagct acacttgtac
     8881 caaatttatc catcaaacga tcttcgcttt ctcggatata atatggtttt tcctttgcta
     8941 gccttgggat ttttttcttt tcttttccat cattttgatt taactcagaa acaagctgtt
     9001 ccagttggcg gacagttaaa ttttcagtta ctgcacgatt ggctaatttc aagatcaatg
     9061 ttttattttt taaacctaac agcgtacggg cttgtcccat agataaacgc tgatcttgta
     9121 ccatttcctt gacaagatcc ggtaaagaaa gcaagcgcaa ataattggcg atataaggtc
     9181 tgctctttcc taaacgacta gctacttctg cttgtgttag tttcaggttt ttcatcagca
     9241 tctcatatgc ttctgcttct tctaacggat tcagatcttc tcgctgcaag ttttccagca
     9301 ctgctacttg catcatcgct tcttcgtcaa agtctctaac gatagcaggg atcgtttctt
     9361 tttcagctag tttggacgct cgaaaacgtc gctcccctgc aataatctca tatcctttta
     9421 ctgcggaacg gcgtacgatg atgggttgaa agacacctga ttgttcaata gaattagcta
     9481 gttcctgcaa agatacttct tcaaatgttt tacggggctg atacggattt ggtcgcagct
     9541 cattcaatgg tagctggaca acggtatcat cttttacatc caccgtctct aagttttcta
     9601 aatcttgaaa cagtgcatcg attcctcggc ctaatccttt acttttcttc acgacttacc
     9661 acttcctttg ccaatgcttg gtagacttca gctcctcgag aacgtggatc gtagtcgatg
     9721 atcggttttc catgactagg tgcttctgat aaacgaatat ttcttggaat gatcgtttcg
     9781 taaacttttt cgcggaagta tttacgtact tcttctacga cttcatttcc cagatttgtt
     9841 cgtgcatcat acattgtcag taagactccc tcgatctcta attctggatt aaagtgtttt
     9901 tggactaaac gaaccgtatt cagtaattgg cttaatcctt ccaatgcgta atactcacac
     9961 tgaacaggta tcaaaatcga atcacttgct gtaaatgaat tgattgtcag atggccaaga
    10021 gaaggcgggc aatcgatcaa aatataatca tactgactgc ttacttctgc taaagatcct
    10081 tttaatcttg attctcttgc catcattgac gtcaattcga tctctgctcc tgctaattgg
    10141 agagtcgcag gcacaatact caaattttcg tgttcagtga tcaaagttgc ctcatcaatt
    10201 ggcaattcat tgactagaac atcatagatg tctcttgtca catcaggttt tctgatcccg
    10261 acaccactgg tagcatttcc ttgtgcatcc atatccacta gcaatacttt tttgccaagg
    10321 ctagcaagac aagcacctag attcaccgtc gtcgttgttt tgccgacgcc acctttttgg
    10381 ttcgcaacag atattatttg tgccatctct tctcctccta tttgattggc tgcttattag
    10441 gcagtccggg ctttcttggg tatttctttg gggttggttt ctttttttga ataacgatga
    10501 tatgccgttg atcagagaca ttcggcaagg taaccgcctc ttctttgagg aatttaccac
    10561 ctaataaagc aatcgcttgt tttgcttctg tcaattcctc ttcacttttt gctgctttca
    10621 atgcataaaa atagccttct tgtttagcca agggcaaaca caattccgct aacacattca
    10681 aacgagcaac cgcacgagca gtgacaaggt caaatgatgc acgaaagtga ggattttgcc
    10741 caaatgtttc tgcccggtca tgatataagg aagcatcgat tcctaataat cgggttaact
    10801 cagataagaa ggttattcgt ttattcagag aatcaacgat cgttatctgc agttctggaa
    10861 aggcaatttt taaaggtatg ctaggaaacc ctgcccccga accaacatcg cataaagata
    10921 aaggttgcgt aaagtctact tcaaatgcta atgtaagtga atcgtaaaaa tgcttcagat
    10981 atacgtcttt ttcatccgta atagctgtaa ggttcatctt ttcgttccat tcgactaatg
    11041 tccgataata aatagcgaat tgattcattt gatgatcggt aagctctatc cctttttctg
    11101 ccaaggattg gcgaaattct tctggtatca taaatattcc tttcattgtg aaacagcaat
    11161 tgtttcacag attctctccc tactttaacg caaaatctct agacatgcaa tccttccata
    11221 tggattctta aaaatttgaa aagtaagaaa agccgataga ctttttcttt ctagtatgac
    11281 tcataaaata tacacagaag agagaactag ctttgagcaa tttctgcaaa aactagttct
    11341 ctcttctatt tattattacg tattacgctg gttcactgac tttcgcaatc ttcccttgtt
    11401 cgatatagac cattaggata cttaggtctg cagggtttac gccactgatt cggctagctt
    11461 gggcaattgt ttctggttgg attttctgca atttttgttt tgcttctgtt gctaatccgt
    11521 tgattgctgc gtagtcgatg ttttctggaa tctttttcgc ttccatgcgt tttaattttt
    11581 ctactttttc catggctttt ttgatgtagc cttcatattt gatttggatt tctacttgtt
    11641 cgatttcttt tcgtgtcaat tcttcatttt ctggaataaa ccgtagaagt tctgcataag
    11701 taatctcagg acgtcttaaa aagtcgcttg ctagtacacc atcttttaat ggtgccgcat
    11761 taatcgttgc taaaaagtct tggacttctt ctgttggttt gattcgtaca ttcatcaaac
    11821 gtttgatttc ttgttcaact gcttcttttt tcttcaaata attcttgtat tgatcttctt
    11881 ttactaagcc tacacggtga cccatttctg ttaatcgcaa atctgcatta tcatgacgta
    11941 aaagcagacg gtattcagca cgtgaagtca gcaaacgata aggttcgttc gttccttttg
    12001 ttaccaaatc atcgatcatg acaccgatgt aaccgtcact tcgtttgatc actaaaggtt
    12061 cttttccctg aactttcaaa gctgcattga taccggcaat cagcccttgt ccagccgctt
    12121 cttcataacc gcttgtacca tttgtttgtc cagctgtata aagattttca acgactttag
    12181 tttctaatgt cggacggagc tggtgtggct ctactacgtc atattcgata gcatatcctg
    12241 tacgcatcat ttctactttt tctaatccag caatagaatg aagcatgttg acttgaacat
    12301 cctctggtaa agaagtagat aaaccttgaa catagacttc ttccgtattt aagccttctg
    12361 gttccaaaaa taattgatga cgtggtttgt ctgcaaaacg cacgatctta tcttcgatgg
    12421 atggacaata gcgagcgcct accccttcaa cgatccctgt aaacattggg gcacgatgta
    12481 agttgtctcg aataatttgg tgagtcgtct cacctgtata ggtcagccag caagattcct
    12541 gatctagttt ataggcacta tctggtgtgc tgaagctaaa atgattcggc tctttgtcac
    12601 caggctgctc ttctgtaaca gaatagtcga tcgtacttga ttttactcga ggcggtgttc
    12661 ctgttttgaa ccgttcgata gcaaagccaa gttcttttag atgattcgct agtccaatag
    12721 aaggttgaga gttattcgga cctgatgaat atttcaattc accgataatg atttctccgc
    12781 gaagtgctgt tccggctgta ataacaactg ctttggcccg gtagctcgct cctgtggacg
    12841 tcactactcc atgacaaaca ccatcttcga cgatcagttc ttcgacgatt ccttgtctta
    12901 gcgtcaaatt tggttctttt tcgatcgtat gtttcatttc tgttgaataa gcatgtttgt
    12961 ctgcttgtgc tcgcaatgct cggacagctg ggccttttcc tgtgttcaac atacgcattt
    13021 ggatataggt tttatcgata ttcttaccca tttctccgcc taacgcatcg atttctcgaa
    13081 cgacaacgcc tttagctggt ccgcctacag aaggattaca tggcatgaat gctaccatgt
    13141 ccaaatttat tgtcagtaat aatgtttttg atcccatacg tgcagcagca agtgcagctt
    13201 ctgaaccggc gtgtcctgcg ccaacaacga tcacgtcata cgcatctgct tcataatgtt
    13261 ccaatcgttt gttcctcctt ttattttcct aaacaaaatt gactgaataa ttgagtgatt
    13321 agctcatctt gtacactgtc gccgacaact tctcctagat agtcccagca acgcgtcata
    13381 tctatttgaa cgagatccac aggcattcct gaatcaatac ctgcaatgac ttcttcaagt
    13441 gagagggaag ctttttctaa caacgcgata tggcgggtat tagaaacata agtagcgtct
    13501 ctttctcctg tttctccgct gaagaataaa tcagaaatag ctgattccaa acgatctagt
    13561 ccgtcgtttt tagctacgga aattgaaaaa actggttcat tttcgatcaa tttcttcaat
    13621 ttttcttgtt ccagctgtgc tggcaaatct gttttattta gaagaatgat ccgtttcaat
    13681 ccacttgtcg cttccaataa ttgttcatct tctgctgtca gtggttcgct ttggtttaga
    13741 acaagtaaga tcaagtctgc ttctgctaat gcttttcggc ttctttcgac cccgatccgt
    13801 tccaccacat cttctgtttc ccgaattcca gctgtatcga ttagcttgag cggtaccccc
    13861 cgaacattga catactcttc gattacatct cgagtcgttc ctgcaatatc cgtaacgatt
    13921 gctttttctt ctcttaacaa atggtttaac aaacttgatt tgccgacatt tggccggccg
    13981 atgattgccg tacttaaccc ttcccgcaga accttccctt gcttggatgt agcaagtagc
    14041 gcttggattc tttgttggat catctgcgct ttttcaagca ataacttcgt agtcaattct
    14101 tcgacatcat catattctgg ataatcaata tttacttcta cttgtgctaa tgtctctaaa
    14161 atctcttgtc tcaatgagcg gatcaaagca gacagattgc cgtctaactg attaagagct
    14221 agtcccattg ctttgtctgt ttttgcccga atcaaatcca tcacagcttc tgcctgtgaa
    14281 aggtcaacac gaccattcaa gaatgctcgt tttgtgaatt cgcctggctc agctaatctt
    14341 gcaccttctc ttaacaatag ctgcaaaatt tgattgacta caacgatccc accgtgacaa
    14401 ttgatttcta ctacatcttc ccgcgtaaat gtctttggtg ctctcatcac ggagaccatg
    14461 acttcatcga caagctgatt gctcttggga tcaacgatat gtccataatg gatcgtatga
    14521 cttggtactt ctgataatcg tttgtttcca gattgataaa ctttatctgc tagttgcaca
    14581 gcttgatcgc cacttaaacg aacgatactg attgcacctt ctccaggtgg ggtagaaatt
    14641 gccgcaatcg tatcaaattc taaagtaatt tcagccattt tttcacttcc tttttcattt
    14701 tgcgcacaaa aaaagtgccc actccaccct ttatgcacaa taaacggtga acttcgcact
    14761 ttgactgctt gttcttgatt aaattctggt catagattat cacacttgct ataaggaatc
    14821 aagtgtttaa aacaattaga tgaagttgag cctgttctgc ttccattacc ttatatttaa
    14881 ttgtccttgg atgtctcttt gcgttctttg gtttattcga agagaagata ctgtataaac
    14941 aaggctttat ctttcttaaa aaaaacggta cactaaatgg tagcgctatc taaactatac
    15001 acttttgaaa ggagaaaata tgtgagcccg ttcagatctg ctgcattgga agaagaaagt
    15061 gaccctcgga tcaacgatgt cgttttatct acagggaata tcaaccagaa atatatcgtc
    15121 cgcgatatcg tttttgttgt ggaatgctta gaagctgatt tgtttgaccc atcttttccc
    15181 aaagatgacc ttttcttaac aacgaagagg aaattaaaga cgaaggtact tgaatatggt
    15241 gcgaatgcag taatcaactg tcattttgag tatcagcaaa aaaaacgcga cggaaagtat
    15301 tttctggaac tttttgctta tggaacagtg atccaattta tccaaacaac gattggttaa
    15361 atgaaacaga caaaaaaagc ggatcaaaac tgaagacagt ttcgatccgc ttttttctat
    15421 caaagttagt gactacttca tcgtatactc tgataagaat gatttctagt aaaatatact
    15481 tggtttgaaa aactttgtca acgtgattta ttcaaaaagt aatggaatca ataatatttt
    15541 ttagcaggtt ctactactaa ataacgataa ggttcctcac cttccgaatg tgtttttaca
    15601 tgttcatctt tgcttaatgc agcatggatt tgtttacgtt caaatgcagg cattggttct
    15661 aagaaaacag gctgccctgt ccgttttact ttttcagccg tgcgatcagc taaacgctga
    15721 atgatctctt ggcgcttttc acggtaattg cctacattga ctactacaga cagcttattt
    15781 cttgctaaac gatggatgaa gacttgtgcc agatattgca atgcattcag tgtttttcca
    15841 tgtttcccaa tcagtatgcc ttgcttttgt gtttctaaat ggaaaacaac catattattt
    15901 gattctcttt ccattttgac aagagctgga gcatcaagct gttttgaaat ttcagtaaga
    15961 taaactgcca attccgttaa agctgcttca tcacctagct cacttacttc ttctgttttt
    16021 tcttcaagaa tcgtttcgtt gactacctcg atctcagctg ttggttcttc ttccaaaatt
    16081 tcttctacag tctgttctac tgtttcagaa actttttcgc tgatacttgg ctggatcgaa
    16141 agccgtgcat tctttcgacc cattcctagg aaaccttttt ttccttcttc cagtatttcg
    16201 atttcgactt ggtctttggc caaacccaaa tcagccagac ctagttggac agcttcgtct
    16261 attgttgcag cttcataaat cggcattagc attacctccc ctattatttc cgttttttct
    16321 taggattcat tgctttctta agagcacgtt ctctttcgcg gattctccgt gcttcttctt
    16381 cacgctcttt tcgaattttg aaagggttgt tgatcagcag cgtttgtaca acttggaagg
    16441 cattggaaac tacccagtat aatgaaagac cgctggctaa attgacaccc atcactaaaa
    16501 tcattacagg catcacgaaa ttcatgatct tcattgatgc attcgattca atttgactca
    16561 tgctagataa atacgtactt gcaaaagtaa agattgctgc taaaatcggc aaaataaatg
    16621 ttggatccgc gttccctaag ttcaaccata agaaatgccc ttgtttcaac tctggtacac
    16681 gtgaaataga ttgccataac gccatcaaga ttggcatttg tactaataaa ggaagacaac
    16741 cagcatatgg attgacgcca ttttctgcat ataaacgctg ctgctcttct cttaacttac
    16801 tttgtgtttc cggatctctt gaactatatt gttgctgcag tgcttttaat ttcggttgta
    16861 attcttgcgt tttacgcatg ctctttgttt ggaaatgcat caacggcaat aggatcacgc
    16921 ggatgatcag tgtaaataaa atgatcccta tccctgcatt accaaatgac aacgccttga
    16981 tcgcctcagc aaagtaataa acaatataac gatcccaaat tcctgtactc tgtgcgctga
    17041 cttccccagt tccgcaaccg gataagacga tgaccaaact aacgataccg gccatcaaaa
    17101 gtaaacgttt gtatttcttc acttactctt ttcctctctg tcgattattt ttgcaagttt
    17161 taagacgtgg actaaattgg agcgaacctc atcataagtc aaccccttca cacttggtct
    17221 agcaatcaca ataaaatcca actccggatc aatttcttct tttatagaat aaactgctgc
    17281 tcggattttt cgtttgactt cattgcggtt taccgcgttg ccgacctttt ttcctacaga
    17341 taaaccaact cgaaaatgag gctgtcccgg tttttccaaa cggtaaacga cgaatttgcg
    17401 gttagcaaaa gaatctcccg tatggaacac ggcttgaaac tctcgttctt tttttactcg
    17461 atacgctttt ctcattagtt ttctttcctt ttctatctct cacttacgct cataatcata
    17521 ccataattac gattgtcctt tcatcatttc cctaaaaaag agtataaaaa aaaccactga
    17581 aaccccagtg gcctaagctg aaagaacttt tcttcctttg cgacgacggc tagctaacac
    17641 acgacgtcca tttttagtac tcatacgttt acggaatccg tgaacttttt gacgtttacg
    17701 tttatttggt tggtatgttc ttttcatata ttccacctcc aaaatgttct tatctatttt
    17761 ataaacacag acatactttg atagtataac gacaaagtag tgattttgtc aatataaaat
    17821 agaagatcga ttgttaaaac ttatccacaa gattattttt ttctatggga atcctatgtg
    17881 gaaaaagtta tgcacaggga ttatccacag ataataaaag gctggtttta cacagaaaac
    17941 acacgtgtaa aaaaagtaat ccacaatcag gcgatttcct gtgtattccg tctcctaact
    18001 attggtatat ctgtattttt tatccacaga cgcaagagga aatctattgg tttttacgag
    18061 ttttccacct gtgcattagt ggtgtggaaa actttttttg acaactgtgt ttttctcttt
    18121 tttctttttg tcgattgtgt ggataattgt aattaaaaaa tttttttctt cggtttctgt
    18181 ggaaaactat tgaaaaaaat gctaaattag tactagttat tcacttttta atgaaggagg
    18241 aggccttata tggtatccct cgatgcttta tggaatgaat taaaagcaac ataccaaaag
    18301 gatttatcgc ctgctagcta taatacatgg atcgaaacag cgaaccctcg aacccttgat
    18361 caaaaccagc tcgttgttga ggttcctagc aagattcata aagaatattg ggaaaaaaac
    18421 ctggcgacaa aaatcgttga agtcggttat atgttatcag gaaatgagat tatccctcgc
    18481 tttattactg gcgaagaagc agagcaagaa gaagttatag aagaaaaaaa tccaaaagtt
    18541 gtggcaccta gtccgctaaa aaaagccatg ctgaacccta aatatacctt tgatacgttt
    18601 gtcattggta aaggaaacca gatggctcat gcagcagcgc tcgttgtagc agaagatcca
    18661 ggttctattt ataacccgct cttcttttat ggaggcgtgg gacttggtaa gactcacttg
    18721 atgcatgcaa ttggtcatca aatgctgcaa agtcagccta atgccaaagt aaaatatgta
    18781 agcagtgaaa cttttgctaa tgatttcatc aattcgatcc aaaacaaaac agcagaagag
    18841 ttccgtcaag aatatcgaaa tgttgattta ctgctagtgg atgacattca attttttgca
    18901 gaaaaagaag ctacgcaaga agagtttttc catactttca atgccttgta caatgaaggg
    18961 aaacaaatcg tactaaccag tgatcggttg ccaaacgaga ttccgaaact gcaagaacgc
    19021 cttgtttctc gctttgcatg ggggctgtct gttgatatta caccgccgga tcttgaaaca
    19081 agaacagcga ttttacgtaa aaaagcggcg gctgaacgtc tagagatccc agatgacaca
    19141 ctaagctaca tcgcaggaca aattgattct aacattcgtg aattagaagg tgcgcttgtt
    19201 cgagtgcaag cttttgctgc gatgaatagt gaagatattt cgactagtct agctgcagac
    19261 gcactgaaaa cgttaaaatc aggaaaagga catcctcaat tgtcaatcct gcagatccaa
    19321 gaagaagtgg caaagtatta tcacatccaa ttgaaagatc tcaaaggaaa gaaacgcgtc
    19381 aaatctattg ttgttcctag acaaatcgct atgtatttgg cacgtgagct cacagataat
    19441 tctttaccga aaatcggagc tgaattcggt ggcaaggatc atacaacggt tatccatgct
    19501 catgaaaaaa tccagcagct gatggattct agtgtcagta tgcaaaatga agtatcagaa
    19561 atcaaaaact ttttactaaa ttaatttgtc gattctatca actgaaaata gcatgtggat
    19621 aaaagaaaaa aacgttcaaa agttatacac actttttcca cagctgtttt ttcgtttctc
    19681 tcttacgttt tttgagtttt ccacagaatc aacatgccct attactttta ttattctttt
    19741 taactaataa taaataaaca aacattcaaa ggagatacat catgaaagtt actttaaacc
    19801 gagctagctt tatgcaggaa ttgcaaactg ttcaacgagc tatttcaagc aaaaccacga
    19861 tccctatttt gacaggtgta aaaatcacac tgacacaaga aggtttgact ttgacgggga
    19921 gcaacgctga tatatcaatt gaaacttttt tgtctgttga aaacgaaaaa gcaaatatgc
    19981 aaatcgaatc tactggttcc attgttttac aagcacgttt ctttagcgaa atcattcgga
    20041 gacttcctga agaaacattt actttagaag ttttagaaaa taaacaagta gcgatcactt
    20101 ctggaaaagc gaattttatc gtaaatggat tagatgcaga taactatcct catcttcctg
    20161 ttgtcgaaag ccataaccag atgaaattac ctgtacacgt attgactaaa ctaatcaacg
    20221 aaacagtttt tgctgtctca caacatgaga gtcgtccaat cttgacaggt gtgcatttca
    20281 ttttatctga taattcttta ttagctgtag ctactgattc tcaccgtcta agtcaacgcg
    20341 tgattccagt agaacaagcg gctgatcatt ttgatattgt tattcctgga aaaagtttga
    20401 tcgaattatc tcgctcatta acaaatgaag aagaaatcgt cgaaatcagc attatggaaa
    20461 accaagtgtt gttcaaaaca gaaacgatgt atttctattc ccgtttgcta gaaggaaact
    20521 atccagatac caatcgtttg attccttcaa gttttaatac agaggttgaa ttttctgttc
    20581 ctagcttttt agcggcgatc gaacgggctt ctttactttc tcatgaaggc cgtaacaaca
    20641 tcgttcgttt atctattcgt ccagatgcgg ttgttttata cggaaattcg ccagaaatcg
    20701 ggaaagtaga agaaagcttg agttatacag caagcagtgg cgatccatta gatatttctt
    20761 tcaatccgga ttatatgaaa gcagcgttgc gtgcatttgg agatatgagc atcaaagtga
    20821 aatttatctc tgctattcgt ccatttacat tggaaccaac ggaagatggc gttcaattta
    20881 ttcagctgat tactcctgta cgtacaaatt aacaatgatt ttcaatgttc ttgaaaattt
    20941 aattgaaaag aaatagaaaa aataaaattt taaacagaag gccctaaaat ctcttttaag
    21001 gctttctgtt tatttttgtt taaatcacct tttttagatt aaatcgtctt atatggaaaa
    21061 atatatggat aaatttgttt tattgcgaaa aaaaaggtat aatagagtat acttttaata
    21121 atgaaaatga gggatgggca ttgaaacaac aagtcattct aaatacggaa ttcatgacgt
    21181 tgggccaaat gttgaaagaa gtcacagtta tcggtagtgg cggacaagca aaatggtatt
    21241 tggcagaaaa cactgtgtta gtcgatggcg aaccagaaaa tcgtcgtgga cgcaaacttt
    21301 atcccggcat gatggttgaa gttccagaag taggaacttt ttttatggta aaaaaaggaa
    21361 acgacgataa tgaggctgaa taagctgtat ttaaaaaatt atcgaaatta cgaagagctg
    21421 aacatcgaat tttccaagaa cctcgtcatc tttttaggag aaaatgcgca aggaaaaacg
    21481 aatcttttgg aaagtatcta cgtattagct atgacgcgaa gtcatcggac aagtagtgag
    21541 caggaattga ttggctggac tgacgatcag gcgatgattc aaggagagat cacaaaaggt
    21601 tcatccactc ttccattaga aatcttatta tctaaaaaag gccgaaaaac caagatcaac
    21661 catatcgaac agaaaaagtt aagtacttac gtgggacaaa tgaatgtcat tttatttgca
    21721 ccagaagatc tttctttagt aaaaggcagc ccgcagatca ggcggaagtt tttagatatg
    21781 gaattaggcc agatcaatcc aatctatctt tatgatcttg tccaatacca agcaattttg
    21841 aaacaaagaa accagtactt gaagcaattg aatgaaaaaa aacaaactga tttgctttat
    21901 ttggatattt tgtccgaaca actagcagcg tttggcagca aagtattgaa agcaagagca
    21961 cagttcgtca agcgattgga gttttgggct aattctttgc atcagcaaat cacccatcaa
    22021 aaagagcagc tggaaatcga gtatctcacc gcagtcgatt ctttagaaac acatacgcaa
    22081 gagcaaatcc aagaacaatt tctcgcactt ttgaaccaaa ataaaaagaa agaccttttt
    22141 cggggaacaa cgacagttgg tcctcatcgt gacgatcttt ccttttttat taatcagaaa
    22201 aatgtgcaga cttatggatc gcaaggacag caaagaacaa ctgcactaag tgtcaaatta
    22261 gcagaaatcg atttgattaa agaagagaca ggggaatatc caatcctttt gttagatgat
    22321 gtgatgagcg agctggatga taatcgtcaa ctccatctgc tagaaacaat cgaaggaaaa
    22381 gttcaaacgt tcttaacaac aacgacactt gaccatgtaa aaaataaaat gactgttgaa
    22441 cctgagattt tttatgttca acaagggaaa ctaaaaggag aagaaactga atgacagaag
    22501 aaagaagttt agtagaacgc gctaaagagt atgatgccag tcagattcaa gtacttgaag
    22561 gacttgaagc cgttcgtaaa cgacctggca tgtatatcgg ttcgactagt tctgagggtc
    22621 tgcatcacct tgtttgggaa attgtcgata attcgatcga tgaagtatta gcaggttttg
    22681 caacgaaaat ccatgtgatt attgaaaaag acaacagtat caccgttatt gacgacggtc
    22741 gggggatacc tgtagatatc caggcaaaaa ctggacgtcc tgcagttgaa acggtcttta
    22801 ctgttttaca tgctggagga aaattcggcg gtggtgggta caaagtttct ggtggacttc
    22861 acggagtagg atcttctgtt gtaaacgcgc tttctacaca gcttgatgtc aaagtataca
    22921 aagaaggaaa tgtgtactat caagaatatc gtcgtggagc tgtagtggac gacttaaaga
    22981 ttatcgaaca aacggatcgc catggaacaa cggttcactt tacgccagac cctgaaattt
    23041 ttacagagac aactgagttt gatttttcaa aattggctac ccggatccgt gaacttgctt
    23101 tcttgaaccg cgggatgcgt atatcgattg aagacaaacg agaagaagaa ccagtcatca
    23161 atgaatacca ttatgacggc gggatcaaaa gttatgtcga atacttgaat gcaaacaaaa
    23221 ccgtgatttt tccagaacct gtatatttgg aaggtgaaca gcaagatatc gcagttgaag
    23281 tctctatgca atatacagac ggctaccatt ccaatatcat gagttttgcc aacaatatcc
    23341 atacgtatga aggtggaaca catgaatcag gattcaagac tgctttaact cgtgtgataa
    23401 atgattatgc ccgaaaacaa aagctgatga aagaaaatga cgacaacttg accggtgaag
    23461 acgtgcgaga aggattgaca gctgttattt ctatcaagca tcctgaccct caattcgaag
    23521 gacaaacaaa aacaaaattg ggcaattccg aagtacggac agtcactgat cggttattta
    23581 gcgaacattt catgaaattc ttgctggaaa acccaagtgt gggccggcaa attgttgaaa
    23641 aaggattact agcttccaga gctcgtctag cagcgaaacg tgcgcgtgaa gtaacgagac
    23701 gtaaaggtgc tttagagatt agtaatctgc caggaaaatt agcggactgc tctagcaacg
    23761 atcctgaaaa atgcgaattg ttcatcgtcg aaggagattc ggccggcgga tcagctaagc
    23821 aaggtcgtaa tcgagagttt caagccatct tgcctattcg tgggaaaatc ttgaatgttg
    23881 aaaaagcaag catggacaag atcttggcaa atgaagagat ccggtcttta tttactgcta
    23941 tgggtacagg gtttggagaa gattttgatg tatcgaaagc tcgctaccac aaattagtta
    24001 tcatgactga tgccgatgtc gacggcgcgc atatccgtac attgctgctg actctttttt
    24061 atcgttacat gcgtcctatt gttgaagctg gatacgtcta tattgctcag ccacctttat
    24121 acggggtaaa acaagggaag aatattacgt atgtacaacc aggaaaaaat gcagaagaag
    24181 agttgaaaca agtcgttgct tcacttcctg cctcaccaaa accaagcgtt cagcgttata
    24241 aaggacttgg agaaatggat gatcatcaac tatgggaaac aactatggac ccaagcaatc
    24301 ggatgatggc ccgcgtcagt gtggacgatg ctattgcagc agatcagata tttgaaatgt
    24361 tgatggggga tcgagtagaa ccccgtcgtg cattcatcga ggaaaatgca cactatgtga
    24421 agaacttaga tatttaatca tgaaggagga aaaagaatga gtgaagaaat cagagaaaac
    24481 atccatgatg tcaatctaac cagcgaaatg aaagactcct tcatcgatta tgcgatgagt
    24541 gttattgtcg cacgtgcact tcctgatgtc agagatggtc tgaaacccgt tcatcgccgt
    24601 attttatacg gcatgaacga attaggtgta acaccggata aagcccataa aaaatctgcc
    24661 agaatcgtcg gagatgtcat gggtaaatac catcctcatg gagacattgc gatctatgag
    24721 tcaatggtac ggatggcaca gccattcagc taccgttata tgctagtgga tggtcatgga
    24781 aactttggtt ctgttgacgg tgacggtgcc gccgctatgc gttataccga agcacggatg
    24841 agcaaaatcg ctacagaaat gctgcgtgat atcaataaga acactgttga tttccaaagc
    24901 aactatgatg atacagaaaa agaaccagtt gtactacctg ctcgcttccc gaatctttta
    24961 gtgaacggaa caacggggat cgccgtaggt atggccacga atatcccacc tcataacttg
    25021 tctgaggtag tagcggctat cgatttgctg atggataatc ctgatgtgac gaccaatgaa
    25081 ttgatggaag tattacctgg accagatttt ccaacaggtg gtttggttat ggggaaatca
    25141 ggaatccgaa gagcgtatga aacaggtaag ggttctatta ccgtacgtgc aaaagttgag
    25201 attactgaga tgccaaatgg taaagaacgg atcatcgtga cagaattgcc ttatatggtc
    25261 aataaagcaa aattgatcga acggatttct gaactgcaca gagacaagcg tatcgaaggg
    25321 atcacagatt tgcgggacga atcttcccgt gaaggtatgc ggatcgtcat tgacatccgt
    25381 cgtgacgcca gcgcatccgt tatcttgaat aacttatata aattgacatc cttgcaaaat
    25441 tcatttggat tcaatatgtt ggcgatcgaa aaaggtgtgc cgaaagtttt gagcttgaaa
    25501 caaatccttg aaaactatat cgaacatcaa cgcgaagtca tcacacgacg gacggtcttt
    25561 gaaaaagaaa aagcagaagc aagagcacac atcttagaag gtttgcgtat tgctttggat
    25621 catatcgatg aaatcattgc gattatccgc gggtctaaat cagatgacga ggcaaaagca
    25681 acaatgatcg aacggttcga tttatccgat cgccagtctc aagctatttt agatatgcgt
    25741 ttacgccgat tgaccggttt ggaacgggaa aaaatcgaaa atgaatacca agaactctta
    25801 aaactgattg aagatttaac tgacattctg gcaagaccag aacgtgttac agaaatcatc
    25861 aagaatgaat tagcagactt gaatcaacga tttggtgata aacgacgcac agaattacta
    25921 gtcggtgagg tcttaagtct ggaagatgaa gatttaatcg aagaagaaga aatcgttatt
    25981 acattgacaa acaatggtta catcaaacgt ttggcaaata atgaattcag agctcaacga
    26041 aggggtggac gtggtgtcca aggaatgggt atccacaatg acgacttcgt caaaaatctg
    26101 gtttcttgtt ctacccatga tacattgtta ttctttacga ataacggaaa agtgtatcgg
    26161 gcaaaaggat acgaaattcc agaatacggg cgtacagcca aaggaatccc aatcatcaat
    26221 ttactaggta tcgattcgag tgaaagcatc caggcaatca ttgcggtgac gggagaagca
    26281 gaagaaggcc actatctctt ctttacgacg cgtcaaggta cagtaaaacg tacttctgtc
    26341 actgcttttg ctaacatccg aagtaatggt ctgatcgcaa ttggtttgaa agaagacgat
    26401 gagctcgtca atgtgctact gacagatggt caatctaata tcattattgg aacacataac
    26461 ggctactctg tcactttcaa agaagaagca gtccgcgata tgggacgtac agcttccggg
    26521 gtcagaggga tacgcctgcg tgaggaagat tatgtcgttg gggcagcctt aatgaaggaa
    26581 aatcaagaag tattagtgat cacagaaaaa ggttacggaa aacggacaaa agtatcggaa
    26641 tatccagtga aaggccgcgg aggtaaaggg atcaaaacgg cgaacatcac tgaaaaaaat
    26701 ggtccactag ctggattgac cactgtttct ggagatgaag acatcatgct gattacagat
    26761 aaaggtgtca ttatccgttt caacgtatcg actgtttctc aaactggacg ttcaacatta
    26821 ggcgtacgtt tgatgaagat ggaagctgat acgaaagttg tcacgatggc agcagtcgaa
    26881 ccagaagctg cagaacaaac agttgaagaa caaggatcag aagaataacc atcaagacta
    26941 agtgtgtaag ctagcaagaa taaccgatta aaaaatctgg ttattcctgc tggctttttt
    27001 gattagttga atttctctta aaatattcga aactgttcat tctgtattgc ttttgaccaa
    27061 aatagagtgt ataattagag cttgtgagta gtctaattaa ttagataact ctccttgctc
    27121 ttaggaacct aagagccgaa agtccacagg gaggtgaata tcaatggaaa acacgaaata
    27181 tgaaatcatg tacattattc gtccaaacat tgatgaagaa gcaaaaactg ctttaatcga
    27241 acgtttcgat gcaatcttga aagataacgg agcagaagtt atcgaatcaa aagattggga
    27301 aaaacgccgt ttcgcttatg aaatgaacgg ttaccgtgaa ggtatctatc acatcgttaa
    27361 agtatcttct ccatcatcag caaatgctgt caatgaattt gaccgtcttg ctaaaatcaa
    27421 cgacgatatc attcgtcaca tgattgttaa agaagaagct taattgttgt ttcatgtgaa
    27481 acaatagaaa acgatgagag gagatgacta ttttgattaa taatgttgta ttagttggac
    27541 gtctgacgaa agatccagat ttgcgttaca cagcaagtgg tacggcagtc gcaacattta
    27601 ctttggctgt gaatcgtaat tttacaaacc aaagcggcaa tcgcgaggct gattttatca
    27661 actgtgtgat ttggcgcaaa tcagcagaaa ctttagcaaa ctatgctcgt aaaggaacac
    27721 ttttaggtgt tactggacgt atccaaactc gttcttatga taatcagcaa ggacaacgtg
    27781 tatacgtgac agaagtagta gctgacaact tccaattgct ggaaagtcgt tctgcatctg
    27841 aaaatcgcca acaaagcggc ggattccaaa gttctggtca atcagctggc ggatttggcg
    27901 gaaacaataa ctctaatcaa acatctcaat catccaacgg tatgcctgat ttcgaccgtg
    27961 atacttctga cccattcggc tcaagttcaa cgatcgacat ttcagacgat gatttaccat
    28021 tctaaacgaa tttgatagga gggaaataga atggcacaac aaagaagagg cggacgtaaa
    28081 cgtcgtaaag tagactacat tgctgctaac catattgaat atatcgatta taaagatatc
    28141 gaattactaa aaagatttat ttcagaacgc ggtaaaatct tgccacgtcg tgtaactggt
    28201 acaggcgcta aaaaccaacg taaaattact gttgcaatca aacgcgctcg tatcatgggc
    28261 ttgctacctt tcgttagcga agactaataa atcctaggaa ttgaatgact gatccttttg
    28321 atcagctatt caattccttt ttttctgtaa aaataacctc tattcgttta gtcgctcgaa
    28381 tgacgaaagt tatggtaaaa tcaaattagt catatatggg aggaaaatta tggaaaataa
    28441 aaacaatcat ttatccccga aacctctctt ccttatcctg tttatattaa tcgaagtatt
    28501 ggtagtctta attttaccat ttcgttttgt tagcgcttcg gtcattctat tgatgaattt
    28561 atggggtgtt cgctattggt tgaaaatgaa acgttggctt attttaaata aacgtgaaaa
    28621 aatccagcag gcttcgactg tagctgaaac caatctagct tatgtctcag aagtcatgcc
    28681 tgtaggagtg attgcttatc agccatcaag ccaaaaaatc gaatggctca atccattagc
    28741 attgaaaatc aaagatcaaa gtggattaac agaggaagaa ttgctagata ctttttttac
    28801 tgcaaaagaa aaaaagaaaa accaagtcta tctagcagat aaaacatttc agtttgatat
    28861 ggatacagta aagggtgttg tttattttaa tgatattacc caaaaccagt tgttaaaact
    28921 ccatcagacg aacagtcagc cggtgattgg tattttatct attgataact atgcagatgc
    28981 cattgataaa ttagatgaca aagagatttc ttatttgaac tctttcgtca ctacactagt
    29041 ttctgactgg atgaatgaat accatgtctt tttcaaaaga atcaacgcag aacggttttt
    29101 cttcgtagca cagatgatcg atctgaaaaa gatgatggat aaaaaatttg atttgctgga
    29161 tcgctttcga gcagaagctg aaaaacagag ctcgcctatc acccttagta tggggattgc
    29221 ttatggctca agaaccctcg atgaaatcgg tggagaagct cagaataatt tagatgttgc
    29281 tttagtccgt ggaggcgacc aagttgtcgt gaaagaggta aaagaaggag caaaacctgt
    29341 ttattatggg gggaaatctg ctaagaatgt caaacgcacg cgtgttcgtt ctcgagcgat
    29401 gagtaccgct ttgcgtcgga tttttgatga aacaggcgat gtgtttatca tggggcacaa
    29461 gtttccggat atggatgctt taggctctgc ttttggtgtc agttgtctgg cacgcttcaa
    29521 ccagaaaaaa gcttacatcg ttatcaatga gaacgagatc attccagatg tagaacggtg
    29581 tcttgaagaa atccataagc atcctgaatt agaaatgcaa ctaatctctc cagaacgtgc
    29641 catagagctg aaaaaagaag aggacctcct cgtgatggtg gattaccata aaccttctct
    29701 atcgatctct cagggcctat atgagcaatt tgataagatt gtgatcattg atcaccatcg
    29761 tcgtggggaa gagtttccaa gtaaacctct gctgacttat attgaatctt cagcttcttc
    29821 agcttcagag ctagtttctg agctgatcca ataccaaagc agcaaaacaa atcgcttaga
    29881 tcgttttgag gccacattat tgcttgcagg gatggttgta gatacaaata gtttcaatgt
    29941 ccgtacaact gcacgaactt ttgacgttgc cagctattta aggtcttgtg gagcagacgc
    30001 atccttagta caatatttat tgagctcgga tttagcgaca tacttggaga tcagcaattt
    30061 gattgctgga agcgactatg tgacttctga tattgttgtg gcggcaggga cagacgaaaa
    30121 agagtataat agtgttatag cagcaaaaac agcagataca ttgctttcga tgatcaatat
    30181 caatgcagct ttcgtcatta caaagcggac agacggcttg attgggatca gtgccagaag
    30241 taccggcacg atcaacgtcc aaatcatcat ggaatcctta ggtggcggag gacacttcac
    30301 aaacgcagct actcaactgg aaaatacgac agttgaggaa acaaaacaga agctatttgc
    30361 tgcaatcaaa gaaaatatga atcaaatata tgataaggag taatccaaat gaaagtaatt
    30421 tttttacaag atgtaaaagg aaaaggtaaa aaaggggaca tcaaagaagt tccagcaggt
    30481 tatgcacaaa attatctaat caaaaataac ttggcaaaag aagcaacgaa aagcagtatc
    30541 agtcagttag caggacaaaa gaaagcacaa gaaaaacacg aagctgaaat cttggaagaa
    30601 gctaaaaagt taaaagaatt cttggaaaaa gaagatactg tagtcgaatt gaaggcgaaa
    30661 gcaggggaag acagccgttt gtttggttcg atcccttcaa aacaaattgc tgaagggtta
    30721 aacaaacaat acaaaatcaa attagataaa cgaaaaatcg aattagaaaa tccgatccgt
    30781 tcactaggct acacaaacgt acctgttaag cttcatcatg aggtgacggc tacgatcaaa
    30841 gttcatgtcg tacaagaata acaaatcttg atagcgatgt tcagctggta agtataacca
    30901 gaaggaaaaa agacaaaccg aaatttatct gagaaaacag ctgcagcaat gaaagcaaaa
    30961 gctgcaaatc gatttcagat tgatttcggt ttcttttttg ggaacagcaa aatagcataa
    31021 agaaaacgag tataataaaa gagaactatt tttttattac actttcggta cgaatgatga
    31081 cttttctctc attttcttgt aaaatgaagc aattgaagac aaggagcgat acgtatgaat
    31141 gaagtgtggc aggatcgaat cccaccgcaa aatattgaag ctgaacaagc ggttttaggc
    31201 tctgtttttc ttgacgcaga aacgatcatt gatgccatgg agtacataga gccaaaagac
    31261 ttttatcgtc gtggccatca aattattttt gagacaatga tcgagttaaa tgatcgtaat
    31321 gaagcgattg acgtggttac tgtcaaagac cggctggaac aagccaattt gttagaagat
    31381 gccggtggtt taagttatct ctcagacttg gcattagcag ttccgacagc agcaaatatc
    31441 gtctactatg cgaaaatcgt tgaagaaaaa tcattgctgc gtacattgat ccagacagca
    31501 acaggaatcg ttacgaaagg attcgagcaa ggagaagaag ttcaaacaat tttagatgat
    31561 gccgaacgca gtatcttgga ggtttcggaa aaaagaaatc gaagcggctt tttatctatt
    31621 gctgaagtac tgaactccac gattgaaaat atcgatcgac tagctcaaaa caatgaagaa
    31681 atcacaggtc taccaactgg ctatcaaggt ctggataaaa tgacagcagg tttccagccc
    31741 gaagaactaa tcattcttgc tgcacgtcca gcggtaggta aaacagcgtt tgcattgaat
    31801 attgctcaaa atgtaggaac aaaaacagat cgttctgttg cgatatttag tttggaaatg
    31861 ggggcagaat ctcttgtaaa tcggatgctt tgtgcagaag gttcgattga ggccagccat
    31921 ttacgtacag gtcagctttc ggaagaagaa tggtcgaatc tgatcgttgc gatggggagt
    31981 ctttctcgag caaatatttt tatcgatgat acaccaggga tcaaaatctc tgaaatccgt
    32041 gcgaaatgtc ggaaactagc gcaagaaaaa ggcaatctag gcttgatatt gatcgattat
    32101 ttgcagttga ttgaaggtaa cggtaaagag aaccgtcaac aagaagtatc agatatctct
    32161 cgccaactga aaaaactggc gaaagagctg aaagtacctg tcattgctct ttcacagtta
    32221 tctcgtggag tagaacagcg acaagacaaa cgaccagtgc taagtgatat tcgtgaatcc
    32281 ggatcaattg aacaagatgc ggacatcgta gccttcttgt atcgagatga ttattatgaa
    32341 agagaaggcg gagatgacga tgatggaaac gagccaaaaa atgacaacgt catcgaagtc
    32401 atcatcgaga agaaccgaag cggtgcacga ggaacagttg aactactgtt tatcaaagaa
    32461 tacaataagt tttcgtcgct ttcgccaaga gaagaatttt aaagaagagg ttgtgagcct
    32521 tgagcaatcc cgagagctct cgtaagaaga tgcaaggagt aaccgcagga acgactagag
    32581 tacttaattt aaacagatct ccaaagggat tgtgacaaaa gtcttgtcac agtccctttt
    32641 tccgaataaa cggtgttcaa tcagctgacc cttggtatta gctcagcaaa cgtcaaaata
    32701 tgaggaacta ttttgacgtt tgtttctcta atactcaggt caaaacgctg atcttacgac
    32761 ctcttttcct taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatcatca
    32821 aacatgagaa gcagtttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca
    32881 caacctcttt cttaaacggt gttcaaaagc ttgcatctgc ggtaatacgc ccaatcaaac
    32941 gaaaaatatg agaagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
    33001 ttcacaacct ctgattcacg gtgttccaaa agtagcttct tcgaaaaata agtcgaaatt
    33061 tcacaaaaat ttgagaagca attttcgtac attccttctt atttcttgaa gctgaccact
    33121 tctgttacaa cctctttttt aataaccatt ctaaaaagat aaagttcgtt ttttaagcgt
    33181 ttttataaaa taaaaataaa aatcattcga ttttatttga aatatgtatc tattattgat
    33241 acaatggttc aggattaaat aatatagaac gaggtgttca catgtcatct gtagtagtag
    33301 taggtacgca atggggcgat gaagggaaag gaaaaatcac agactttctc agtgaaaatg
    33361 ctgaagtgat tgcacggtac caaggtggcg acaatgcagg gcacacaatt aagtttaacg
    33421 gtgtgactta taaactgcat ttgattcctt ctgggatttt ttataaagac aagatcagtg
    33481 tgatcggaaa cggcgttgta gtcaatccta aatcattggt taaagaatta gcttatttac
    33541 atgaaaaagg tgtagaaaca agtaatttgc gtatttctga ccgcgcgcac gtaatcttgc
    33601 cttatcatat caaattggac caattacaag aagatgctaa gggcgaaaat aagattggta
    33661 caacgattaa aggaatcgga cctgcctata tggataaagc agctcgtgta ggtatccgta
    33721 ttgcagactt attagataaa gaaatttttg aagaacgtct tcgtttgaat ctagatgaca
    33781 aaaaccgtca atttgtaaaa atgtttgatt cagaaccact tgattttgac gatatttttg
    33841 aagaatatta tgaatacgga caacaaatca aacaatacgt cacagatact tccgttatct
    33901 tgaatgatgc tttggatgca ggcaaacgcg tgttgtttga aggcgcacaa ggtgtaatgc
    33961 tggatatcga ccagggaact tatccttttg ttacttcttc taacccagta gccggtgggg
    34021 taacaatcgg aagcggtgta gggccttcaa aaatcaataa agttgtcggc gtctgcaaag
    34081 cctatacgtc acgtgtcggt gatggaccat ttccaactga attatttgat gaaacaggag
    34141 aacaaatccg cgaagtagga cgagaatacg gtacgacaac tggtcgtccg cgtcgtgtag
    34201 gctggtttga ttctgtagtt atgcgccatt ctaaacgagt ttcaggtatt accaacctat
    34261 ctttaaactc gatcgatgta ttaagtggat tggaaacagt aaaaatttgt acggcttatg
    34321 aattagatgg cgaactaatc taccactatc cagcaagctt gaaagagttg aaccgctgca
    34381 aaccaatcta tgaagaattg ccaggctggt cagaagacat tacaggatgc aaaacacttg
    34441 cagaactgcc agaaaacgca cgtaactatg tacgtcgtat ctcagagctt gttggtgtac
    34501 gtatctcaac attttctgtc ggacctgata gaacacaaac aaacatctta gaaagcgtct
    34561 gggcgcaaat ctaaggataa aaacgacgac tgaatcagga cgttcttacc agagcgagtc
    34621 gaagtgttta tctatacgat aataataact tgaagaggta gtgaaagaga cgtttagcct
    34681 tattgccgat aggctgtctc ttgaacactg tttattcaga ataagggact gtgacaaaa
//
LOCUS       DAFLWZ010000023        33996 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000023 DAFLWZ010000000
VERSION     DAFLWZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.023"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(28..1260)
                     /locus_tag="L1V38_001181"
     CDS             complement(28..1260)
                     /locus_tag="L1V38_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBN1315742.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1515..2084
                     /locus_tag="L1V38_001182"
     CDS             1515..2084
                     /locus_tag="L1V38_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1315743.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2262..2702)
                     /locus_tag="L1V38_001183"
     CDS             complement(2262..2702)
                     /locus_tag="L1V38_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBN1315744.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2860..3624
                     /gene="map"
                     /locus_tag="L1V38_001184"
     CDS             2860..3624
                     /gene="map"
                     /locus_tag="L1V38_001184"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBN1315745.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3656..4579
                     /locus_tag="L1V38_001185"
     CDS             3656..4579
                     /locus_tag="L1V38_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBN1315746.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4804..5043)
                     /locus_tag="L1V38_001186"
     CDS             complement(4804..5043)
                     /locus_tag="L1V38_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315747.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5048..5467)
                     /locus_tag="L1V38_001187"
     CDS             complement(5048..5467)
                     /locus_tag="L1V38_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1315748.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5694..6932)
                     /locus_tag="L1V38_001188"
     CDS             complement(5694..6932)
                     /locus_tag="L1V38_001188"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315749.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7039..7674)
                     /locus_tag="L1V38_001189"
     CDS             complement(7039..7674)
                     /locus_tag="L1V38_001189"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1315750.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8016..8651)
                     /locus_tag="L1V38_001190"
     CDS             complement(8016..8651)
                     /locus_tag="L1V38_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1315751.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9163..10305
                     /locus_tag="L1V38_001191"
     CDS             9163..10305
                     /locus_tag="L1V38_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1315752.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10298..10504
                     /locus_tag="L1V38_001192"
     CDS             10298..10504
                     /locus_tag="L1V38_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1315753.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10583..11776
                     /locus_tag="L1V38_001193"
     CDS             10583..11776
                     /locus_tag="L1V38_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1315754.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11981..13120
                     /locus_tag="L1V38_001194"
     CDS             11981..13120
                     /locus_tag="L1V38_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBN1315755.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13113..13913
                     /locus_tag="L1V38_001195"
     CDS             13113..13913
                     /locus_tag="L1V38_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1315756.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13913..14740
                     /locus_tag="L1V38_001196"
     CDS             13913..14740
                     /locus_tag="L1V38_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1315757.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14718..15452
                     /locus_tag="L1V38_001197"
     CDS             14718..15452
                     /locus_tag="L1V38_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1315758.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15552..16418
                     /gene="rfbA"
                     /locus_tag="L1V38_001198"
     CDS             15552..16418
                     /gene="rfbA"
                     /locus_tag="L1V38_001198"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBN1315759.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16432..17004
                     /gene="rfbC"
                     /locus_tag="L1V38_001199"
     CDS             16432..17004
                     /gene="rfbC"
                     /locus_tag="L1V38_001199"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBN1315760.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17026..18054
                     /gene="rfbB"
                     /locus_tag="L1V38_001200"
     CDS             17026..18054
                     /gene="rfbB"
                     /locus_tag="L1V38_001200"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBN1315761.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18152..19003
                     /gene="rfbD"
                     /locus_tag="L1V38_001201"
     CDS             18152..19003
                     /gene="rfbD"
                     /locus_tag="L1V38_001201"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBN1315762.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19037..21070
                     /locus_tag="L1V38_001202"
     CDS             19037..21070
                     /locus_tag="L1V38_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315763.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21114..22394
                     /locus_tag="L1V38_001203"
     CDS             21114..22394
                     /locus_tag="L1V38_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBN1315764.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22604..23410
                     /locus_tag="L1V38_001204"
     CDS             22604..23410
                     /locus_tag="L1V38_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315765.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23422..24642
                     /locus_tag="L1V38_001205"
     CDS             23422..24642
                     /locus_tag="L1V38_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315766.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSNGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24632..26218
                     /locus_tag="L1V38_001206"
     CDS             24632..26218
                     /locus_tag="L1V38_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1315767.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26257..28395
                     /locus_tag="L1V38_001207"
     CDS             26257..28395
                     /locus_tag="L1V38_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1315768.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28763..29746)
                     /locus_tag="L1V38_001208"
     CDS             complement(28763..29746)
                     /locus_tag="L1V38_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBN1315769.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30124..31515
                     /locus_tag="L1V38_001209"
     CDS             30124..31515
                     /locus_tag="L1V38_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1315770.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31531..32571
                     /locus_tag="L1V38_001210"
     CDS             31531..32571
                     /locus_tag="L1V38_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1315771.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32590..33675
                     /locus_tag="L1V38_001211"
     CDS             32590..33675
                     /locus_tag="L1V38_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBN1315772.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33708..>33996
                     /locus_tag="L1V38_001212"
     CDS             33708..>33996
                     /locus_tag="L1V38_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1315773.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGA"
BASE COUNT        11018 a         5825 c         6701 g        10452 t
ORIGIN      
        1 attttttgca tgtgtgcgaa agtatactca agcccaatcg ccatttcgga aaatcggtac
       61 tgtagagcca tcttcacgga ttccgtcgat atccatcttg tcagatccta ccatgaaatc
      121 tacgtgggtt tgacttctat tcaatccagc ttctgctaat tcttcatcgg acatttctgt
      181 accgcctttc acactgaagg cataagcaga acctagtgct aagtgattcg atgcgttttc
      241 atcaaataat gtattgaaaa agatgatgcc agattgagaa ataggtgaag ggtcaggtac
      301 aagtgcgact tctcctaaac gacgcgcacc ttcatctgta tcaagcagtt ttgctaagac
      361 atcttctcct tgttcggcag aaaaatcaac aacttttcca tctttaaaag taaatttcat
      421 acccgagatg atggtgccag cataactcag tggctttgta cttgaaatgt aaccatctac
      481 tcgatgactg tcaggtgctg tgaacacttc ttccgtcggc atatttgcca tgaatttttc
      541 tccacgagca ttatagcttc cagcgccttc ccaaagatgg tttttaggca atccgataat
      601 gatatctgta ccgggagcag tatagtgaag ggcagaaaat tgttctcgat tcaattcttc
      661 tgcttttttt gctaattttt catcatgctt cttccatgct aagacagggt cttcttcata
      721 gacacgagtc gttttgaaaa tctgatccca taatgcctca acttgttttt cttctggcag
      781 ttctgggaag acttttgctg cccattgttt accagccgca gccacgacag tccaactgac
      841 tttatttgct tgagttgcct tgcgtaaatt cattagtgct ttgccattcg ctgattgata
      901 agacgctact cgatggctat ctacaccagc aaatgcatcg ggatcggcag aaacaacgct
      961 gatcctgctt gctccttttt caagccattc atccgcttga tcgattttag attgtggtac
     1021 attctcaata cgatccgttg cagcatgtaa aagaaattct ctttggatct ggtcgtcagt
     1081 ccattgaacg ataacctcag cggctcctag tttataagct tcttgtgtga tcaatcgagc
     1141 aaggggtgcc tgttccacgc tgatctgtaa aacaactgtg tgtccttttt ctgtggctac
     1201 gccagtttct gcaattaagc gtgcatattt ttttagaagt tcattaaaat cagataacat
     1261 aataaaaatt cctcctcacc attttttctg gtaactatta gcatgatacc atttaattat
     1321 gattcaaaca atgaggcttt aaataaaaaa aggaggttat ttttttaagg ttaagtttca
     1381 tgatatatgt tactacttgc tatttcagct tgtgaagaaa atcaaaaact aattttgcat
     1441 atcaaaaaaa acatgttaca atgaaattaa tcaatggtgg aagcgttata aaaaaattaa
     1501 ggagattaaa aaatatggca agaaaaaaga cgattactag agaacagatt ttggcagctg
     1561 cttatgaagt agctgccacc gatggattta cacgatttac tgcgagaaac atcgcgaaca
     1621 aaatgaattg ttccacgcaa ccgatttatc ttgagtttaa aaatatggat gacttgagac
     1681 aagctctttt tgagcagatc tatgatcatt tacaatatga agtgttcact gttgagcata
     1741 cagggaatac gattatcgat cttgctttta attatatcca ttttgcaaga agagagaaga
     1801 agttgtatcg ttcactgtac ttagaagaat atggtggagg aaaagagatg cagaatttct
     1861 cttatactta ctttgtgaat acagtgaaac gcgatccagc ttatgtgaat ctttcagaag
     1921 agcagatcga atctttgtat aatgggacat ggatcatagc tactgggatc gcagctttga
     1981 tgtcttcaag catcatccat ccaactgatg aacagattga aaagatgatc caagacagta
     2041 tagatgctat cttgaaattc aaagaaccaa tcgaaatcga ttgaatatac tcaaaagttc
     2101 cacaaatcag taggtaacaa gagatgtgtc aaaataagga aaagttcgtt tttcttacag
     2161 cgtatgcatt tttaactccc gaagaactct tccatgaatg caatgaataa aagagccata
     2221 cagattgaat aaatctggat ggctctttta ttgcaagtat attaaatttt tgcgactagt
     2281 tctttagcga aagcttctaa attttcgata tcttcttctt cagcattcag atccacttta
     2341 acattttcgg ctccttttga tgcgcctgtt tttgcaaaag cagcatcgaa atcatccacc
     2401 gatttgcaga attcatcgta aaaagtatca ccagatccgc agacaccgta aatttttccc
     2461 aatagatcca attcttgcaa gtcttcataa aagtctacga tctcatcagg cagatcgcca
     2521 tcatcgtatg tataagtagc tactacgcaa atatctgcct cctcgaattc atctgcatct
     2581 acttgggtac attcgttgat ttcgacttcg atatccagat tttcaaatgc ttctgcaaca
     2641 atatcggcga tttcttcagt gtttcctgtc atgctagcat atacgatttt tgctaaagcc
     2701 atgatgtgcc tcctcgttta taattattta acaattatga attataccaa aacatcattg
     2761 aaaagaaaat aaaacctaga gacacctggg gaatgtcatt tggctaaatg tatgccgcta
     2821 tgttaaaatg agagggattt gtaaaaagga gacgaaaata tgattacttt aaaatcagca
     2881 cgtgaaattg aaatgatggc agaatctgga gctttattag cagatgtaca taaaaatctg
     2941 cgtgatttta taaaaccagg aatcacaagt tgggatattg aggtatttgt cagaaactat
     3001 atcgagagtc atggcggaat tgctgcgcaa attggctttg aagggtatga atatgcgact
     3061 tgtatcagta taaatgatga aatttgtcat ggattccctc gtaaaaagcc tttgaaaaac
     3121 ggtgatttgg taaaagtcga tatgtgtatc gatttgaaag gcggcatttc tgattcttgt
     3181 tgggcctatg tagttggaga atctacacct gagatcgacc gattgatgga agtaacgaag
     3241 aaagctttgt acatcggtat tgagcaagca caagtaggga atcggattgg tgacatcggt
     3301 catgctatcc aaacttatgt agaaggcgaa aatctagcga tcgttcgtga ttttattggt
     3361 catggcgttg gtcctacgat tcatgaagaa ccagcagttc ctcattacgg agaagctgga
     3421 aaagggttgc ggttgaaaga aggcatggtt atcacgatcg aacctatggt taataccgga
     3481 acttggaaaa tgaaaatgga tcctaacggc tggactgcgt atacaagaga cggcggactt
     3541 tcttgccaat atgaacatac attggctatt actaaagatg gtccaagaat tttgacatca
     3601 caaggagaag aaggcactta ttgatctatc cagtcaatag gtacgggaga ggtacatgaa
     3661 agtttggaac aaaataaaac aaaatgaaaa tctgatgcgc tttattgaga cgactcaaaa
     3721 gcgcatcact gattcagaaa tgagtacgac ctctgtcgtc gttgcttatt atttactctt
     3781 gtctttattt ccattgatta ttgcttttgg taatatttta ccgtttctcc acatcgatca
     3841 agagactgta ctgacctatt tacgagaagt gattcctgag accgtttacc agtttatcgg
     3901 tcctgcaatc aaagaccttt tgacacaaag ttcaggaggc ttgttatccg tttctgcatt
     3961 agcggcttta tggtctgcaa gtcaaagtat caatgctttg caaattgcga tgaataaagc
     4021 gtatggcgta gaaaatagaa aaaatttttt gatcgtccgt ttcttctcac taattgtcat
     4081 tgtcttgttc atgattgcta ttagtggggt aactatcgtt cttgggttgg gacagctgat
     4141 tttggatgct attcagccaa tcgtacaaat acccgtgaac tttatcgatc agttccaaac
     4201 tttgaagtgg ccaatcacat tggtagcttt atttgtcatc atgttcttga tttatttaat
     4261 tgtccctaat gctcagttga agttgaagac gatcattccg ggcacgatct tcgctactgt
     4321 cggctggatg ctgttatcac aagtgtttag tatctatgct aggtattttg caacgaggat
     4381 cagcggttat cagatcatag gaagttttat tgtactcatg ctttggctta attttgctgc
     4441 tacgatcatc attttgggcg gaatcatcaa tgcagttgtt caagaatacg tgacgggtca
     4501 tcaaatcaaa aaacgtcgag atccaagccg aaaatggttc aataaattga aaactaaatt
     4561 ttctcataaa aaaaagtaga aacaagagtt cttattgtaa atttatatca gtaatttatt
     4621 tgaaatttta tatctaattt tcaattatcc gcataaacac tatacattca agcattttga
     4681 agtatagaaa aacactcatc ttaccacgaa tttaccacga ttgaatgagc cttgatatga
     4741 ccgtaaaact actaagggag atagcacgaa actgtgtatc tcccgatttt tttatacagt
     4801 tgattacttc actccgattt caaatttcaa tattgctttc atcatgtctg tatgaatttc
     4861 tccttttagt tcttcatcaa cctgcataat gattttacca ctttcagagt ggtaaaaagg
     4921 acgcaagcat aatttagaaa tataaccgtc ataaaacttc aaaatctctt taactgccat
     4981 ttcatctccg cttgacgctt tgcaaatcaa ttcaaaagag ggatagccat aatctttact
     5041 catttcttta cttcctttcg ctcaaaagca tttttaactt ccttagtcct ctagttcttc
     5101 tactgcaaat agcagaacgt gatacatggt acagttctga aatttctctg tcgttcattc
     5161 cttgaaaata acgtaataaa atcgcactac gctgtttttc tgacagtcta tgtaaaactg
     5221 taccaagtgt ttcatcagat acataaattg taaagtgcaa gactttaaat gatacacaat
     5281 cataaaaaca ggtatcaatc gttccacgtt caacttgttt cgtttcggct atttcacaaa
     5341 acaatacttc acgtttagaa tgtcttgcaa gctgtctgtt tcgacttttc actttgttct
     5401 taatgacaat cagcattaaa gaattgaact gtaatctgac gatatgctcg aaagaagatg
     5461 tcctcataat ctcaccccct ttctgctaat gctgaaatat ataaacggaa taccgtttat
     5521 accctttaga aatacagaaa aatggtaaga aaaaagccca cacaaaacat atatttgtgc
     5581 gagccttaaa tactgcaata ttactctttc ttttataaca ctatcctttt agcagatttc
     5641 aaattttctt ttatatattg tttttagcct aacatactat ttaacccctt gtattatatc
     5701 tctaactttt gaaaaattct ttttgaatat attgaaatca tgattgaagc aatagaagct
     5761 acaaacataa caacccatgt ttcttgtata aatacatcga ataaaatacc gtaaaccatt
     5821 tgtccaatag gttgaccgca catagcaact gctaccagcg tagccattat ctttcctact
     5881 aattgcggtg gtgtttgtgt ctgaacaaga gtgtaaattt gaacaacaaa catagtagat
     5941 acacccatag ccacaaagca catcactgta actacccagt aggaaactat tgcaggcaat
     6001 tctaaaaata gcgaaattcc cataagtaaa acagaaacag aacaaataag taacaaggta
     6061 taaaggtttt ttagttttaa ctttgaagca acaagagctg ttaaaatacc accacataaa
     6121 ccacctaatg ataatgctga ttgtgaaaaa ccatatagtg tatctggcat ttttaaaact
     6181 tcagaaatta agataggcag accaacaatt aaaacagcac ttaaaaccaa attgaaaatg
     6241 caaaccaaaa agattacgga tataaaaatg ggtttctcct ttttcaaaaa ggtataacta
     6301 tcttttaaat cgtttttagc aactgcaatt acacctactt cacgaggtct tttttggtgt
     6361 ggaatatgga taaaaatttc cataatggct gaaaaagtaa aacatataat actaacaatt
     6421 aaaatgggat tgataccata aaattgaaaa actactccgc ttatagctgg tccgataaag
     6481 tttgctaaag tatttacttg atttattata gcattaccga cggtaagttt atctgatgat
     6541 accaatagag gaatacttgc ttgtaccgct ggttgatatg caccagaaat accataaagt
     6601 aacatcaaag caacaataaa caaaggtatg ataggaattt ttcccaatga caaataaaat
     6661 actaaaatta tgattgctgt tacaaaatct agtatgacca taatgtttct tttatttgtc
     6721 ctgtcagcaa taataccacc taccagcgac aaaataacca taggtaaaaa agagcaggct
     6781 gtagcaatac caaacaaagc tgatgaacca gtttctttta acaaatagta cggtaatgca
     6841 aatcgtagga tagcgtttcc aaataaagaa attatctgtc ctataacaac aagtataaaa
     6901 tcacgattaa aaagtttttt ttctgcttgc ataaaatctc tcctttttat ttaatcaaac
     6961 agaccgtcgg tttatataat ggtttaaata aactgctctt ttatagagca gtctatcgta
     7021 tagggataac aaatacagtt atttacaaaa ctgtataaat gcagaaattg tttcttcgtc
     7081 taataatgtg tctatgccta ttccatttaa aagggcattg aatgtattgc aacgtttttc
     7141 cataccctct ttatccgtca tttcaactaa tgggttgagc catacattac ttaataccat
     7201 gataacttct gcaatttcat gtgaattttc aatctccaaa gacttatcct tgataccttg
     7261 ttctaaaacg ggttcaacaa attcaggtac tacaatttca tacatttgtt ctatttgcat
     7321 agcaagaaaa cgaggattgt ttaatagttg aggagaaact gtcaataaaa cgctttggtt
     7381 agaattgaat accgctgtct taaatatttc tcttaacttt tctaaaccgt ttaaactatc
     7441 gttatctcta attttagcaa atattactgc attttcattt ccaattcttt gaaaaattgc
     7501 ttttaaaata tcttcctttg aatcgaaatg atgataaata gcacctttag aaagttttgt
     7561 ttcattgata atatcttgca atgatgtgtt atcatatcct ttttcacaaa acatttttgt
     7621 agaaacatct aaaatgagtt ttactgtttc ttctggatat ttatttcgtg ccataactta
     7681 cctccaatac aaaccgttgg tctgattaaa gtatatctta gtattttatg cttgtcaata
     7741 taaagacttg caattttata aaaatgcaga atgcaagcct ttttcattta ttctacaatc
     7801 ttccagttgc tttccttatg cggtgtcaat tcatactgtg atacctgcgt tgcctttgcc
     7861 tgatttacca caaatcagat tttatccctt tcttcctctt gattgcccac aacagaaaag
     7921 aaaaagccct gtcaagagct ttgccaccat tggtggtgct ttgcactctt gatcgggctt
     7981 tttgtttgct gtatcttctc gcaagaggaa aaaagttact cgtcctcatc atcaaaattg
     8041 ttattcctta atacttctcg taacagttcc atatcttctt ttgagttcgg gtttatcatt
     8101 ttcacgactt gataaggtgt cttatactta tgtccctcta tgctttcccc aaacatatcc
     8161 atactgtata aatcatcata gcggtctaat aatttttgaa acttcaaatg ctggataaat
     8221 tctttgattg ggtaaaggtc ggacgcttca atgcttttcc cgttgatata gtctgtaata
     8281 tattcccgta acttttctaa ctcatattcc agccattctt cctcgctgtc aaagaagtta
     8341 tcatagtgtc catgtttcag ttctgcattt agacgttctt cggctcttaa aaactgacag
     8401 acttcctttt cagattgatt gacatacttc cattctcccg acaacaattc attgggcgta
     8461 acgtccagca cttccattat cttttccagc gtttcatagg caggatagtt caaccctctt
     8521 tcaatcttgg aaaggctctg catattgata ccgattttgt ccgcaagttc ctgttgtttc
     8581 attcccctaa attttcttat ggtctgtata ttatttccta aatggcttat tttcattgca
     8641 taaccctcca tatctcgtta tatcttcgct attataagtc tatcatgctt aatatgattt
     8701 gtaaaggcaa aaaaagatat tgacaaataa gcatataaga attactatgt tcttgtaatc
     8761 gaataagcac aatagaatga aatataaaaa cattcaaaaa gaaataccta tctgattaaa
     8821 tccgtagata tgaatatcgg ttgaaatgga acttgttaga aaaggcaaaa cagaacttgc
     8881 tgacaaagta tttctgacac ggtggcggaa gcctctcagg cttaccgcca tgacaccttg
     8941 tgtcaagggg aagaaatgct ttgtcggctg gcgagcctgc gagccttgtc tgtgcccccg
     9001 ttatctaaca ggggggcact atttcacaaa agacaagtca aaaaccatac acccccaaac
     9061 ctgtgagtag taatgagagg ttttaagaag atagtacata tcacactttt tgaaaggtgg
     9121 tttacaggta tttcaaggct attgtgggat tggaggaata caatgaacaa tttagaattt
     9181 gcacttgaaa tgaagaacaa acgtcttgcc agcggtcttt cacaaggaga acttgcaagt
     9241 cttacccatg tatcaagata tagtatcaac cgctttgaga acggaaaagc taacgccagc
     9301 aaggaaacac agaacattat cctgcgttgt ctgaattact atatctgcga taagcctttt
     9361 tatctgctcg ttgattatct gtctgtccgt tttccaacga ctgacgcatt ggaagttatc
     9421 cgaaaggtgc ttggcatgaa agcagattat tttatccatt atgactatgg gtattatggc
     9481 tataaggagc attatgctta cggggaaatc aaggtcatgg cttctgatga tgaacacatg
     9541 ggcgtatttt tagaattaaa aggggcaggc tcacgcaaca tggaatatgt cttacaggca
     9601 cagaacaggg actggtattc attcttaaac cgctgtcttg actgtggcgg tgttatccga
     9661 cgttttgact tggcaatcaa tgatatgtgc ggtctgctgg atattcctgt gctatctgaa
     9721 aaatacagaa atggtggtgc ggaatgtcgc tgtaaaaact atgaaaatgt acaaggtgga
     9781 aaattaagcg gaaaaaaccg taatttagca agtacccttt atatcggctc aaaggcaagc
     9841 acaaaatatt tctgcctgta tgaaaaacaa aaggaacagg caacgaaaaa gaaacatacc
     9901 gatattatca accgttttga aattcgtctg cgtgacaaaa aggcggtaca ggcagttgaa
     9961 gaactgttat tgacgtataa ccctcatggg ctggtgtttt atctcattac cgattttgtg
    10021 gaatttcctg actatccatt gtgggagata ttcatttccc atgacagttt accttttgaa
    10081 atgaaccctg tacctgtcaa tatggaacgc actctgcaat ggctggaaag acaggtcatg
    10141 ccgtcaatcg tgatgataga ggaaatcgac aggctgacag gttcaaacta catgaaaatg
    10201 attgatgaat gtacccacct ttctgaaaaa caggaaatgc ttgtggaaca gatgtgtacg
    10261 gacatatcag acgtaatcga aagtgagggg gtgttttatg agtaatacac aggatattcc
    10321 cgtatgggaa aaatacaccc ttaccattga agaagcgtca aagtatttcc gcattggaga
    10381 aaacaagtta agacgattgg cagaggaaaa caaggacgct ggctggctca ttatgaatgg
    10441 caaccgcata cagattaaac gccgacagtt tgaaaaggtt attgataaat tggacgcaat
    10501 ctaatgcaaa tgagccttgt atgtgttatg atgaacacaa gtcatatcaa ggctctttcc
    10561 aacaaggaaa ggagcagaca ccatgaaaga aaaaagacgg gataacaaag gtcgtatcct
    10621 gcatactgga gagagccaac gaacagacgg aaaatactta tataaatatg tagacgcatt
    10681 gggaaacaca aaatatgtgt atgcttggag attgacaccc acagacccga caccaaaggg
    10741 aaaacgggaa aaaccctcac ttcgagaact ggaacagcag ataagacggg atattgagga
    10801 cggtatcgac agcacaggca agaaaatgac gctttgccaa ctctatgcca aacagaacgc
    10861 acagaggaca aatgtgaaga aaagcacaca gaaacaacgg gaacaactca tgcggttatt
    10921 aaaagaggac aagttaggtg ctaggagcat tgatacgata aaaccctctg acgctaaaga
    10981 atgggcgtta cgcatgaaag acaaaggctt ttcctacaat accattaaca accataaacg
    11041 ctcgttaaaa gcgtcattct acatagccat acaagatgat tatgtgagga aaaacccttt
    11101 tgatttcaag ctaagtgaag tcatagaaaa tgataccaaa gagaaagtcg cattgacaga
    11161 ggaacaggag caagccttat tgtcatttat taagacggac aacgtgtatc acaagcatta
    11221 tgatgatgtg ctgatactgt taaagacagg acttcgtatc tcggaactgt gcggactgac
    11281 agtagccgac attgatttca agaatgaagt tgtgattatc gaccaccagt tactaaagag
    11341 taaggaacag ggctattata ttgaaacgcc taagacgaaa agcgggataa ggcaagtgcc
    11401 attaagcaaa gaaacgatac aggcatttca acgggttatc aacagccgac caaagataaa
    11461 gtcgatagag gtagacggac acagcggttt tgtgtttatc aatccgaaag gtaatccaaa
    11521 agttgccatt gattataacg ccttatttat ccgtatggta aagaaataca acaagcacca
    11581 caaggacaat cccttgccac atattacacc gcatacgcta cgccatacat tctgcacaag
    11641 gctggcaagc aagaacatga acccgaaaga tttacagtat atcatggggc attcaaacat
    11701 cagtatcaca atgaactggt acgctcatgc gtccatagat accgcaaaat cagaggttca
    11761 gcgtctaatc gcatagaagt atttaccacg attttaacca cgattgacag ggaaaatata
    11821 agaagataga cctagatatg cgaggtttac cacaaaagca aaatgcccgt agagccgata
    11881 aaataaggct ttgcggacat ttgagaagat ataaaaagat agtcaaaaag acatatataa
    11941 tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt cttttagtat
    12001 ggttataaga ttttttctga caattttatt atcactgata ttaacacctg tattcaaaat
    12061 catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa ataaagttcc
    12121 aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga ctttattctt
    12181 attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt ctttagtaat
    12241 catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa aaagtatagg
    12301 gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg attccttcac
    12361 gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa cgattttttg
    12421 gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc tggcggcagg
    12481 gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc tccatgcttc
    12541 tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg gtttttttcc
    12601 ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat tcctagggtt
    12661 tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt catcgatttc
    12721 tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca ttaggagaaa
    12781 agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc gactaatcag
    12841 tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt tgatgttttc
    12901 tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat tgattattgc
    12961 catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg agaaacatca
    13021 gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc aagtaaaaca
    13081 gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac cagccgatcc
    13141 ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat aattttattt
    13201 caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat tcacttcccg
    13261 agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc tattttcatg
    13321 atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc gattctcgct
    13381 atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca gcattggtct
    13441 tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt aatgaagatg
    13501 gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt ttgcgctttg
    13561 tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt gaatgccgag
    13621 gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt atggtagctg
    13681 atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg tactttgaag
    13741 acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac acaccctttt
    13801 atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg tttcgcgtgt
    13861 ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc tgatgaaacc
    13921 agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc cagcttatgg
    13981 accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg ataatagtcc
    14041 tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc atgatccgca
    14101 aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg aaggaacacg
    14161 ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg aactattgcg
    14221 taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt ctgggagccg
    14281 acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag cagtagaagt
    14341 tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct ggtctgtcaa
    14401 atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt tggatcattg
    14461 gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg tacgaatgga
    14521 acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc gttctatttt
    14581 acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca gtcaccgacg
    14641 acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc atatctggcg
    14701 gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt tcggtttgta
    14761 tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt ttatctcagc
    14821 tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat acatgggata
    14881 tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg cctcgtcaag
    14941 gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta atctttttgg
    15001 cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac tattttgagc
    15061 agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc gagctgcaag
    15121 agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt aataatgtga
    15181 taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa cccgatattt
    15241 tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg ggaggaaaga
    15301 agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta aacgcgagtg
    15361 agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat ctgattacgg
    15421 cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc ttaatatttc
    15481 catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat caaaaaggag
    15541 agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt ctgtaccctt
    15601 taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg atttattatc
    15661 caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca acgccacaag
    15721 atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg cagatcgaat
    15781 atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga gaagaattta
    15841 ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt ggcggtctgt
    15901 ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt ggctatcatg
    15961 tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa gctttgtcga
    16021 ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt tatttttatg
    16081 acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga gaactagaga
    16141 ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa cttatgggac
    16201 gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca tctaccttta
    16261 tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa attgcttacc
    16321 gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg aaaaaaaatc
    16381 aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca gatgaaagta
    16441 acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg cgatcatcgc
    16501 ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt gaaatatgac
    16561 tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg gcttcatttc
    16621 caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc agttttagat
    16681 gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg atttatctta
    16741 tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg attcgttact
    16801 ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc agaagcagat
    16861 gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga tccatcaaga
    16921 gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga agcagaaaat
    16981 ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa aaacatcatt
    17041 gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt aaacaatcat
    17101 ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa agagaacttg
    17161 gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga tgcagaatta
    17221 gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga atcccataac
    17281 gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg tacgtataca
    17341 cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac tgacgaggtt
    17401 tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga aggagaaaaa
    17461 ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa agctggttca
    17521 gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat ttcaaactgt
    17581 tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca agtaacgaat
    17641 atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg tgactggatc
    17701 catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag aattggcgaa
    17761 acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga attgatctta
    17821 gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc aggacacgac
    17881 ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa gcctgagttt
    17941 acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca tgaagactgg
    18001 tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca ataatacaga
    18061 gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc tgtctctttt
    18121 ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag gaaatgggca
    18181 actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg tttcaacaga
    18241 tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca cagaattaaa
    18301 acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag aagaagaagc
    18361 aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac ttgcagcaaa
    18421 agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg gaaaaaacaa
    18481 aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg gtcgtacgaa
    18541 attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca tacgaacttc
    18601 ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc tagcggaaac
    18661 ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga cacgtacttt
    18721 ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt atcatttgtc
    18781 gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag atacagatgt
    18841 agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc cgcagtattc
    18901 agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt ggcaagaagc
    18961 acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt ttatcaaata
    19021 gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag aaaagccaaa
    19081 agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc gctatcttat
    19141 tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt cacttggtgt
    19201 ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga tttttggaca
    19261 gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc tctcacaagc
    19321 tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa acatgatcat
    19381 tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca actggggatt
    19441 ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat tagtcgtcat
    19501 ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag ctctatcgct
    19561 aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca tgcaacatgt
    19621 gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt atttctacaa
    19681 tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt tcggtattgg
    19741 gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc tgatttttta
    19801 ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt tggatgtagt
    19861 gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct ggctaacgtc
    19921 aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg taagtactgg
    19981 aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa ttccttttga
    20041 agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt ttccaactgt
    20101 attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa agttactggg
    20161 acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg ggttgccaaa
    20221 atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca tccttacttt
    20281 tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga gagaagatgt
    20341 tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt atttctatgc
    20401 gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg cagttgctgt
    20461 gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt tttacctcgc
    20521 ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag aaggtacagg
    20581 agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac aagatcctgg
    20641 taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg gagtgaaatc
    20701 cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg atccgaaaga
    20761 agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg ctaaggaaga
    20821 tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt ttgaagacgc
    20881 agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt acaaccaatt
    20941 atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata tgatttttaa
    21001 agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa atcagctagt
    21061 cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg agagtggaga
    21121 taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc ttgcttttgt
    21181 tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca actttgttta
    21241 tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc attttaaatg
    21301 tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc cttttcattt
    21361 tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta ctgtttcctt
    21421 tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg gatcgcggta
    21481 tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt atatcgtgta tttacagaga
    21541 tccaagtacc agaaggacaa agcatctggg ctccaggcaa ttcgctttct gatatttgga
    21601 tcaatacgaa tataatcgga agttctttga tgactcttgc tttattgatc agtggatttg
    21661 ccagttcttt tgaacgatgg tatgtacgaa tcatcggtgc agtagcagtt gttgcagctt
    21721 ttctcgggat ttgggtctgc caatctagag gtgcattagt cgcgttgatt gtttttgcga
    21781 tattggatct tttacctaaa tcgttgatgc gtgtcattcg tgcgccattt attgcttaca
    21841 cggttacgat tcttttagct ttgccgattt cttatctggc ggctgtctct gaaaaagtca
    21901 atttgtttac cggtcgagaa gatatttggc ataaattcta tcagacgcta ggagaaaaat
    21961 ctgaacaaat tttactagga atgaaaacat ttatcttcca acgaggaaac caatttttag
    22021 gaaaccacaa tagttataat tctattttga atatctatgg attgatagga tttgggattg
    22081 ctgctttgct gcttatcctt tttattggtc gcttaacgtt gaaagcagat ttatccaacg
    22141 ggcagatgac ttttatctgg gccttttttg cggtgatgat gcagtcattt atggaggata
    22201 cattgacttc atacccatgg gttccgatta tttatatcct gttggctatg gccgttcatc
    22261 gatatgatga accagaagtt gcggaggaat tctatgttat ggaagaggca tatgacgata
    22321 tgacttatga tgatacatct tatgaggaac aaccagatag cgctcattct tccaggatcc
    22381 aacgctatca ttgataggca caaaatacga gagaggctgt gacaaccgtc gcagcctttt
    22441 ttggtttatt gcaattgtct agcatcttct gtaaaataga aacgttagag aaaatcttgt
    22501 atcatagaaa attaagaaag aaataagaac gcagctcggt accaaaaata tggtaaaatg
    22561 gcacttgact gtaattcact gaaaatcgct tggaggaaca caaatgttta aagatttgta
    22621 tttatttatg aaggacattt atcagaacag aaaattattg ctacagtttt cgatcaatga
    22681 cttcaaatca agatatgcag gatcgttttt aggaatctta tgggcgttta tcaatccgct
    22741 atttactgta ttgatttatt ggctggtatt tggtgttgga ctgaaagcac aaatgatcga
    22801 tgcaaaatac ccatttatcg tatatttagt taccgggatg attccctggt tcttcttctc
    22861 agatgcattt gcatcaacta cggttgtttt tcgggaatat acttatttag taaagaaagt
    22921 cgtattcaat attcgtatct tgcccacgac gaaaatccta tccaatctgt acacccactt
    22981 attcttcatt ctgattggca tagctgtcgc gcttataaat ggtatatatc cttcagcaat
    23041 gtctttacag ctgatttatt atttattttg catgtgtgct ttcttgacag gattgacttg
    23101 gctgacggca tcgatccaac catttttacc tgatatcatg caattaatta cgatcgtgct
    23161 gcagttgatc atgtggacat taccgatatt atggagccct aatcagtttg attcaggtct
    23221 tgtaagcata ttgaaattaa atccgctgta ctatgttgtt caaggttatc gtgagtcatt
    23281 tttaagtgaa gcttggttct gggagcatgg aacatatact ttgtatttct gggttttcac
    23341 gttagtaatg ttcgtaatcg gctctgcagt gttccgtaga ttgaaaccac atttttcaga
    23401 tgtgctgtaa ggagaatagc tatgacagaa tatgcaatta gactaaaaga tatcacaaaa
    23461 tcttataata tgtacgcaaa accttcggat cgatttcgtg aagccctcaa tccttttaag
    23521 aaatcctatc atgatgtatt ttatgcgttg aaaaacgtga atgtagaaat aaaaaaaggt
    23581 gagatgatcg gtttcgtggg agaaaacgga tcgggaaaat ctacaatgtt gaaaatcatt
    23641 acgggagtac tgacaccaac atccggcacg atggaaatcg aaggaaaaat ctcagctttg
    23701 ctagaactag gatcaggatt caatcctgag tattctggct atgaaaatat ctatttaaat
    23761 ggaatggttc taggattttc aagagaagaa gtcgatgaaa tggtcgatga tatcattgaa
    23821 tttgctgaca tcggagacca tatttatcaa cctgtaaaaa cttattcaaa cgggatgttc
    23881 gttcgtctag cttttgctgt agcaatcaat gtgaatcccg atattttgat tgtggatgaa
    23941 gcattggcag taggcgatct tgaatttcaa ctaaaatgta tggaaaaatt tacagaaatc
    24001 aagaactcgg gaaagacgat tttattcgtt tctcatgata tcagttcgat tcgtcgtttt
    24061 tgtgatcgtt cctattggtt gaaaaacgga gaagtcgtcg aatatggcga tacgatggaa
    24121 gtaacgacga attatgaaaa ctttttaaag aaaaaatcag ttaaaacagt ggatcggaat
    24181 aaaaaccaag tagaacggtt cgccgctcca gatatcgtcg acgtgacgaa agcggaattg
    24241 ttggataaag acaaaaatcc ggtggatatg ctggaacaag gagaaaaact atacgttaaa
    24301 gtaacttatg aagtaaaaga tgatacaatc aaaaatccgg ttttaggaat tgcgctacga
    24361 acagtcgaca atttttatgt atgcggactt aatactctac tagatggtat caagattcct
    24421 tggaaaaaag gagagaatat cttttatctg gagtatgaaa agttaggttt gttagctggt
    24481 gaatattatt ttgacgttgc ggtctttgaa gaaaatgcaa cggttccttt ggtatataag
    24541 acaaagtaca tgaacttgtt tgtcagcggt tcttatatcg gagaaggcat cgtggtctta
    24601 gaccataaat gggaagaagg gactcatagc aatgaaatat gattttgaaa tggacctaga
    24661 tgaacaaagc agtgtgggaa aaattgccgc acagatcaaa ccaggaagta aagttttaga
    24721 gtttggtccc ggaaacggcc gattaacgaa acatttaatc ggagcaaaac aatgtgaagt
    24781 gagcattgtt gagttagata aggaattgtt cgattttgtc agcgaatttg ctcaagatgg
    24841 attttatggt gatatcgaaa gttttgagtg ggcaaactat tatgctggac agacatttga
    24901 ttacgtcttg tttgcggatg ttttagaaca tttggtagat cctggaaaaa cattgaagaa
    24961 agtcagagaa tttttgaatg aagaaggaga gatcctgatt acattcccta acttggcgca
    25021 taattctgtc atgatcgatt tgttcaataa ccaattgccg tgggcttctt atggtctcct
    25081 agatgaaacc cataattctt tttatactca tgatggcttc caaaaagttt ttgaaaaagc
    25141 gggattattc attaatattg aagattattt gtacttagct gtaggtgata cagaattaaa
    25201 atcaacttat gaagaattgc cggaagctgt acgctatgat ttcaaaatgc gaccatttgg
    25261 tgaagtctac caatactttt tctcattgat gaaacatcca gtagcacaaa gttccattgc
    25321 agagccacaa aattctaatt atgtaaaagt gttagaagta acccagcaaa cgaaacaaga
    25381 tgaaacaatc caacaaatac cattcaataa tttcacaggg gaaaatgaga cactaagttt
    25441 ccccgtatca gaaacaacag aaagaatggt gtttcgcttc gcgcaacaac ctagctttat
    25501 cgaattcagc gcagaagctg ccggagaaaa actaacattt atcgattcga atgctgtagt
    25561 caaaacagta aatgattgtt atttgtttga tgggaaagaa ttaccagagt tcgttctaac
    25621 ggatatttct gggaaagaag tgactatcca ttgtcactat cgctttatcg gggaattgac
    25681 accaacaatg aaagaattgt tggaaacgat tcgtcccatg gctgaagtca caaagcagct
    25741 ttctgagaaa aatgacgaat tagaaagaga aaatcatcat cttcttgagg aaaatacaag
    25801 actagaccat acgttaaaaa caaccacaaa tcgctattgc acattgttgg aaagtgatga
    25861 atggacaata aaacatagac taggacgacg taagaaagaa acttcgaaaa aaatccaaga
    25921 aaaagaactt tctatatgta ttgacgagaa aatctgggat gcagaaacaa aaatattaaa
    25981 aatcatcgga tggggaatcg ctaattcgga tcgccagccc ttgtcctata agttatcagc
    26041 tgaccaatcg ccatttttcg aagcaattcc tgtttcacga gaagaagtca atcaagcaga
    26101 acagctcgca aaaggaacag aagcgggatt tgagttacga atcctttgcg agcaagaacg
    26161 ttcattctta gtggaagcag tagctcaaaa tggccaatca tggatcattg aaatgtaaat
    26221 aatgattaac ttataaagat aaggagtaaa cgaatcgtgc aaaaaaaaga aattgccgta
    26281 tttatcgatc aaatcactcg tgaacgggcc actggcgatt tgcttattgt gggctgggca
    26341 attgatgaag tgaccaaaga aatccctacg ataaaggtag aaaaagaaaa tgtgattgct
    26401 gaagcaacac atgtcgtaag attggatatc aatcatttat ataatcttga tgttaagacc
    26461 caaagcggtt ttaaggtacg tttatcaggg aaaatgagag gaaaagccat cttagacttc
    26521 caaacagcga gacatcaaaa tggcatagct gtgaaattaa acggtaaata cccttatgat
    26581 gacggcattg aatcttcatg ggaaagaaaa aaaagattac tgaaaaaagg gataaattat
    26641 gcaaggactc atggcgtaaa aaaagcgatc cgtcgggtca aattggaatt gaagccagga
    26701 tcgatcgact atgcagagtg gatcagtcgt catgagaaac cagatttgaa agagcaaagg
    26761 aaagaagcac aaggatttgc gtaccgtcca ttgatttcca tacttatgcc tgtctataac
    26821 gttgaaatca aatggctcga aaaatgcatt gattcggtac tggatcaaac gtatgatcat
    26881 tgggaactat gtatcagtga tgatgcttct actgatccag ctatccgaaa gtgtctggaa
    26941 tcctatcaag caaaagatga tagaatcaaa gtcgttttcc gaaaagaaaa tggacacatc
    27001 agtctggcaa ctaattctgc attggaaata gcagaaggag aatttatagc actcttagat
    27061 aatgatgatg aattaccgcc atttgcatta tatgaagtgg caaaagtgct aaacgtacat
    27121 ccagaactgg atgtgatcta cagtgacgaa gataaaatcg atgcagatgg caatcgcttt
    27181 gatccgcatt tcaaagcaga ctggtcgcct gatacattga tgggaaataa ttatatctct
    27241 cacttaggcg tatatcgaac aagcattgtt aaagaacttg gcggtttccg taaaggctat
    27301 gaaggttctc aagattatga tttggtcctt cgtgtgacag aacaaatccc tgcagatcat
    27361 atttaccaca ttgaccgagt cttgtatcat tggcggacga tcccaggatc aactgcaagt
    27421 aatggcgaag ccaaaagtta tatctatgat tccggagtga aagcattgac agatgccctg
    27481 tctagaagaa acatcaaagg aagcgtacgt cctggcagaa tttctggatt ttatgagatt
    27541 gcttatgacg tcttgcaaga ggatttggtc agtgtgatca ttccaacgaa gaatggctat
    27601 gaagatctaa aaacttgtgt ggattcgatc atcgaaaaaa cgtcttattc aaattatgaa
    27661 atcattattg cggataacgg aagtacagat ccaaaaatgc aagaattatt tgcagaatac
    27721 aagcatcagc tgaaagaccg ctttatcgta gaattgattg acattccatt caattattct
    27781 cgaattaaca atttagcagc agaaaaagca aacggcaaat actttttatt cttgaataac
    27841 gatacagaag tgattgagcc agattggatg acggtgatgg tttcttatgc acagtttgat
    27901 cgaatcggct gtgtaggagc aaaactgttt tatccagatg atacaacgca gcatgcagga
    27961 gtattattag gaatcggtgg tgttgcaggg catgcattga ataactatga tcgaacacat
    28021 tgtggttatt tcggccgatt ggtcattgac gtcaattact tagcagtcac tgcagcttgt
    28081 atgatggtca aggcagctga cttcaatgct gttaacgggt ttgatgaaac attagaagta
    28141 gcattcaacg atgttgactt gtgcttgaaa gtttatgaac tgggtcgtta caatgtctat
    28201 gcacatcaag cagaattgta ccatttcgaa tctaaatcaa gaggttatga agatactcca
    28261 gaaaaacaaa gacgttttgc tggtgaaatc aaaaaaatgc aagataaatg gccagcatat
    28321 attgcgcatg atccatttta caatgataat ttaacaaaag aaggaatcgg cgacttttcg
    28381 ttgagaccag attaaactat aataaaaagc tgttatgttg tgattcgctc gcacataacg
    28441 gctttttata gttttttgtc aaaaaaaggc agaaggtgcc gactcaaaaa aataagtcga
    28501 ggttgggaca gaagtgttta actccgagaa ataagaagaa attcacgaaa attgcttttc
    28561 aaatttttgt gaatttcggc ttatttaaga agaagttgct tctgctccca ccgtttattc
    28621 gtttttaaag aatgagacaa aagtgtttct tacttttgtc ccacgctctt attcatgctc
    28681 agagcgccaa tagatacaaa atcatagcca aagtttcacg aaccctagct gtcaaagaat
    28741 cgatatttta ttttaatata ggctatttta aaataaatgg tttaaggtat tcctctacaa
    28801 aagccactct atcaattatc atgggtttaa aataagaagt gatggagata accagattgt
    28861 tcttagcgtc aatataaaga acatttccac tattaccaat tgctgaatat atttcgttct
    28921 cagaatctaa tacccaccat aaatagccat atctcatatt ttgtaagtct tctaaagcac
    28981 tggttctagg tttgaacatc tcgtttatcc acatgggtgg tacgatttgt tttcctttat
    29041 acatcccttt atttaggcat aatacaccaa tttttgccag atcacttgcc gataaacaca
    29101 aaccatatcc tgccgtcccg atatttagtg gatcacaaaa ccagacattg gttttaggag
    29161 acttatccat tgtaaactgc ttatgttctt cagctgtttc agcataataa ttgacatggt
    29221 ttggtatccc tataggatca aatagatact tattggcaaa atcaacagtt gttagcttac
    29281 ttgtctgata caacaagcca gttaatatgt gtaaacagac agtttgatag ttgaattcgc
    29341 cggttatacc ttttcttcct cccaataaat ctagtgatgt ttttgtccaa tcttcacttg
    29401 aacagacttt tgtccatgga tcgcctttac atttgtaggg tgctttcatt gttagcaagt
    29461 gcttgattgt aatagcgtaa atagttttct ccccgcgttt cactttatac tctggaaaat
    29521 aatctaatac tttatcatcg atacttttga ttaatccttg ctctaaagca atgccaatca
    29581 gcaaagatac aatacttttc gttgctgaca tgatatgaca agtatcgtct tttttataac
    29641 cattccattc atctgtataa acttctaccc catccttata tgcgacaatt tgacatatat
    29701 ttggttgtcg aaaaccaata aaatcatgca actcttgttt attcataaga tattacctca
    29761 ctttcttcta taagcataat gtcattaaaa atcgatttca attttttcga ttcttcacgt
    29821 aatacaggta ttcttatgga ctagacagcg ctttgggaag atggattctc tgaaaaatat
    29881 aaaggttcac tttatgagtg gataaaaaaa gcagcaaata cttcgacttc tttaatttac
    29941 caacattagt gaaaatcgat tcatctggag atttgtaatt tagagtcctt gtcttgatta
    30001 gaggtgtata aagcttttta ttagacattt ttaaattcca ttacaatttg cttataaact
    30061 aggtttttaa aggtgactat ggtaagataa tagagatatt attttgtgat taggagtgta
    30121 tatatgaata aaaatggaga atggagtgct gcacgacgga tattcattat attaatggat
    30181 gttattgtat acaatgcagc aatatatagt agtttcttac tgaagtttcg tggagagatc
    30241 ccattacgaa atttagaaac tttccaacac tcagcaatta ttatttcagt gatttttatt
    30301 gcgttgaaca ttttgttggg tgcatatgtt ttttataatc gaatgatcag tgacatcgtg
    30361 tttgtcacag tcatcggtca ggtattgatg acactaggga tcatggtagt gacttttgcg
    30421 ggccgctggt ttgcttttcc acgtcttgtt atcttacttt catttgttct cggtacgctt
    30481 ttcttaagta tctatcgtat tctcgtatat aaactttatt tacgcgtaag tcgagataaa
    30541 aaggtcgtca ttattgggtt agaaaaggat gtcgcaccag caatccaaaa ttttggttca
    30601 aagaaaaaca acaaacataa agtcgaagca gtcattcttg ataactatta tgcaaacatc
    30661 aaaaatatga ttaaagacat cgatattgtc tatcttgctt ctcatatcga agaaactgaa
    30721 aaaatcaaaa tctatcaatt agttactaaa aatgaaaaaa aattgttttt gaatacaaca
    30781 tttgaaaact tgacattgat caatccaaat attatgaatt tcgaagatga aagtattatt
    30841 gaagcatctg gatttagaat ccaacctgaa tatgaactat tcaaacgttt gtttgatatc
    30901 atcgtttcac ttgttttatt agttattgct tcaccattta tgttattcac agcaatttta
    30961 gtcaaagtga catcaccggg accaatcatc tataaacaag tgcggatcac aaaaaatcaa
    31021 aaggaatttt caatctataa attccgctcg atgaccgcca cagccgaagc aaaatctgga
    31081 ccagttttag ctaagagcaa tgatgcacga gtaacgcctg taggtaaatt tattcgagct
    31141 gtccgctttg atgaattacc acaaatcttc aatgtgctga aaggcgatat gtcgatcgta
    31201 ggaccacgtc ctgaacgtcc tttcttcgtc gatcagttca atgcagaaaa cccttattac
    31261 tacttacggc ataatgttcg tgctggtatc actgggtatg cacaagtcta tggaaaatat
    31321 gtctctgatt acaacagtaa attacgtttt gatttacttt atatcaaaaa atattcattg
    31381 atgcttgatt taaagatctt gctgcaaacc atcaagatcc tatttgataa aatgtcctct
    31441 caaggacttg aagaagacga aaatgtgatc tcattggcag aaattgcttt tccgaatgaa
    31501 aaaatctttc gctagttggg aggcgtaaaa atgaacaatc cgaaattcag cataatcgta
    31561 ccagtataca atgcagaagc aactattggt cgaacgattg atattctaaa agaattggat
    31621 tatgaagagt acgaagtcgt tttagtaaat gatggatcaa cagatcaaac acaggaaatc
    31681 attcaagaac tgattgaaaa tgatgaacgt tttgaattga ttactacgac caatcaaggg
    31741 cccggattag caagaaacga aggaataaga cagtcaaaag gagaatatct cttattcttc
    31801 gatgcagatg acacgccagt aaaaacgatc ttgtcagatt atgatcattt gctagaaaag
    31861 agtccaaaag cggatcttgt tgttagttcg tttgtttttc gtacaatgga cgagggaaga
    31921 atcgtttccg aaaaagaaaa cttagttaca gaatgtcact atctaactca cgaagagttt
    31981 ataaaagaca tgtatcagtt aatgaatgaa cagttgatgt atgttgtatg gaacaaatgc
    32041 tatcgtagcg atattctgaa aaataaccaa attctattta aaacttataa tagttgtgag
    32101 gatcgaatat ttaacttaca ttattatgaa tactgtcatc aagtgatcat gaacccaaaa
    32161 gtagaatata tttatgaatt tgaaggtggg aaggggatca ctaatcaata ccgacctaac
    32221 aagttcgaaa catttaaaga attctattca ttagcaaata ctgtaacaga cgatattaat
    32281 aaagacggta tggcggcgct tcttttaaaa gggacaactt cagttatttt ttctatttat
    32341 agtacctctg caagaacttc aaaagagaag aaagacgaag caaagcagat attgagtgat
    32401 ccagtgatcc gagaagccaa gcaaattgct aagacggatt cttcagcaaa aaaaataaca
    32461 aagttgcttt acaatatgcc agctccacta tttttatctg ctgtaaaagt tggaagcttc
    32521 gttgaagtga aaatgccagg gttaatggct gctttgaagc gagtatatta gttaatggag
    32581 gaaaatataa tgaaaagaat tttgcatttt cagggacgaa tgggtttagg tggagcagag
    32641 tctttcatga tgaatttata tcgtaaaatt gatcgtacaa actatcaatt tgattttttg
    32701 atttatgaag attatgcaga tgttcaagac tatcattcag agattgaaag attaggaggc
    32761 cgtatttttg ttgtacctaa tcctaagaaa aatattttta aatatttaat agaagtgaat
    32821 aagttactaa aaaaagaatc tttttctata gttcacaatc aggtttattt tggcggggga
    32881 attaatttat ggttagccaa aaagaatgga atcagacaga gaattgctca tagccatgca
    32941 actgaagatg gaaaatctca aaatattgta atgaatgtat tgcgtaaatt tttaaccaaa
    33001 ttgttgttac aaaatgcaac agactacctt gccgttagtc aagaagctgg tgaaagtctg
    33061 tttcaaaacc acccctttga gatagttcat aatggtattg atttagagct ttatagtaaa
    33121 aattcagaag ctaaggttaa taagagaaaa gaattggata tctcaatgag tacttttgtt
    33181 gtgggaaaca ttggacgatt agagaaacaa aaaaatcaat cttatttgtt agagattttt
    33241 ttagaaatac taaaaatgaa ttctgattct tacttgattt tagtaggtga agggtcactt
    33301 agaaataaac tgaaagccaa agcagtagaa ttggatatag agaaaagagt aaaattttta
    33361 ggagaaagaa acgatattcc cgagttatta tctgtgatgg atgtttttgt aatgccttct
    33421 ctttatgaag gtctgccaat ggttggatta gaagcacaag cagcaaaatt aaaattagtc
    33481 ttagcagata ctatttccaa agatacaaag ttaacaaata atgtggattt tgtatcatta
    33541 gatgaaacac cacaagaatg ggcaaaaaaa gtaataaaag agccgtatgc taataaaata
    33601 acacaagaac taaagagtta tgatgtttcg tacactactg aacaaatgga gagtatatat
    33661 agtagagatc attaaaaatg ttcaagatat tttaggagtg attatttttg aaaatatgtt
    33721 atttgatatt ggcatacaat gatattggca acttaaagag attggtcaat cgattgaacg
    33781 aaaatgcagt ttttattatt catatagata aaaaaactga tatagaacca tttattgaag
    33841 catttaaatc atatgataat gttgaatttt tatgtaataa aaaccgtgtt aaaatttatt
    33901 ggggtggttt ttccattgta caagcagaaa tcaatttagt aaagagagca ttacaaaatg
    33961 agaaatattt aaaatatgta ttattatctg gtgctg
//
LOCUS       DAFLWZ010000024        33388 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000024 DAFLWZ010000000
VERSION     DAFLWZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.024"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(166..354)
                     /locus_tag="L1V38_001213"
     CDS             complement(166..354)
                     /locus_tag="L1V38_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBN1315774.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            624..986
                     /locus_tag="L1V38_001214"
     CDS             624..986
                     /locus_tag="L1V38_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1315775.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            1038..2720
                     /locus_tag="L1V38_001215"
     CDS             1038..2720
                     /locus_tag="L1V38_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBN1315776.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2837..4873
                     /gene="recG"
                     /locus_tag="L1V38_001216"
     CDS             2837..4873
                     /gene="recG"
                     /locus_tag="L1V38_001216"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBN1315777.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4922..5923
                     /gene="plsX"
                     /locus_tag="L1V38_001217"
     CDS             4922..5923
                     /gene="plsX"
                     /locus_tag="L1V38_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBN1315778.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            6045..6287
                     /gene="acpP"
                     /locus_tag="L1V38_001218"
     CDS             6045..6287
                     /gene="acpP"
                     /locus_tag="L1V38_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1315779.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6555..7559
                     /locus_tag="L1V38_001219"
     CDS             6555..7559
                     /locus_tag="L1V38_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315780.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7560..8504
                     /locus_tag="L1V38_001220"
     CDS             7560..8504
                     /locus_tag="L1V38_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315781.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8504..9466
                     /locus_tag="L1V38_001221"
     CDS             8504..9466
                     /locus_tag="L1V38_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315782.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9493..10407
                     /locus_tag="L1V38_001222"
     CDS             9493..10407
                     /locus_tag="L1V38_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315783.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10433..12214
                     /locus_tag="L1V38_001223"
     CDS             10433..12214
                     /locus_tag="L1V38_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1315784.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12562..13248
                     /locus_tag="L1V38_001224"
     CDS             12562..13248
                     /locus_tag="L1V38_001224"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBN1315785.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13268..16849
                     /gene="smc"
                     /locus_tag="L1V38_001225"
     CDS             13268..16849
                     /gene="smc"
                     /locus_tag="L1V38_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBN1315786.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16858..17667
                     /locus_tag="L1V38_001226"
     CDS             16858..17667
                     /locus_tag="L1V38_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1315787.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17678..18676
                     /gene="ftsY"
                     /locus_tag="L1V38_001227"
     CDS             17678..18676
                     /gene="ftsY"
                     /locus_tag="L1V38_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBN1315788.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18863..21130
                     /gene="gshAB"
                     /locus_tag="L1V38_001228"
     CDS             18863..21130
                     /gene="gshAB"
                     /locus_tag="L1V38_001228"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBN1315789.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21219..21671)
                     /locus_tag="L1V38_001229"
     CDS             complement(21219..21671)
                     /locus_tag="L1V38_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBN1315790.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21821..22771
                     /locus_tag="L1V38_001230"
     CDS             21821..22771
                     /locus_tag="L1V38_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1315791.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22764..23723
                     /locus_tag="L1V38_001231"
     CDS             22764..23723
                     /locus_tag="L1V38_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1315792.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23720..24475
                     /locus_tag="L1V38_001232"
     CDS             23720..24475
                     /locus_tag="L1V38_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1315793.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24498..25451
                     /locus_tag="L1V38_001233"
     CDS             24498..25451
                     /locus_tag="L1V38_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1315794.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(26095..26391)
                     /locus_tag="L1V38_001234"
     CDS             complement(26095..26391)
                     /locus_tag="L1V38_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBN1315795.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26746..27102
                     /locus_tag="L1V38_001235"
     CDS             26746..27102
                     /locus_tag="L1V38_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1315796.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            27112..28011
                     /locus_tag="L1V38_001236"
     CDS             27112..28011
                     /locus_tag="L1V38_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBN1315797.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28528..29259
                     /locus_tag="L1V38_001237"
     CDS             28528..29259
                     /locus_tag="L1V38_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1315798.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29404..31431
                     /locus_tag="L1V38_001238"
     CDS             29404..31431
                     /locus_tag="L1V38_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1315799.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31539..32636
                     /locus_tag="L1V38_001239"
     CDS             31539..32636
                     /locus_tag="L1V38_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1315800.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32943..>33388
                     /locus_tag="L1V38_001240"
     CDS             32943..>33388
                     /locus_tag="L1V38_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315801.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11177 a         5794 c         7146 g         9271 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaataaaaaa ccgttcacta tctgaacggt ccaagtatca ttcaattaaa cgcgttcaac
      181 ttttcctgat ttcaaagcac gagttgacac ccaaactttt ttaggttttc cgtcgaccat
      241 aacgcgaact ttttgtaagt taggtttaac agtacgtttt gttgagttca tagcgtgtga
      301 acggttgttt ccactttttg tcttgcgacc tgtaaagtaa caaacttttg ccatggtaat
      361 ttcctccttt gccttgattt ggagcaatag aataattcag ctcataccag actaacatat
      421 catatagaat ggaaatttgc aagtacattt tcatagatac aattgacaat tgagaagaat
      481 aattgtaaat taaacaaggt tatacctgaa attttgcaag gtttttgagt actttgggta
      541 actgcctttt atttcaagtt gcgctatgat aaaatatgat agaagaaaaa tgggagtttt
      601 ttacccgtta aggaggctca ttcatggctg taaaaattca aacgtcagct ggaaccattg
      661 aaattaccaa tgatgtaatt gcaacagttg ttggtggcgc cgcgacagat gtgttcggtg
      721 ttgtaggaat ggccagcaaa aatcaaatta aagataatat tactgagatt ttgcgtaaag
      781 aaaattactc aagaggagta gttgtccgcc aagaagataa tggtattgct gtagatgttt
      841 atacgattat cagctatggt acgaaaatct ctgaagtttc ccgcaacgtc caagaaaaag
      901 tgaaatacaa tctagaggca ttattaggcg taactgccaa ttcagttaat gtctttgtac
      961 aaggtgttcg tgtactgcca gactaggcag gagactggct ggtaactcag cagtcgatct
     1021 gaaggaggat tatctaggtg agtgtaacag aaataagtgc aagccagttc caggaaatgg
     1081 tccaggcagg tgcgaatcgt ctgcaagtaa atgcagaata cgtcaattca ttaaatgtat
     1141 tccctgtgcc agatggcgat acgggaacaa atatgaatct atctatgact agtggagcta
     1201 aggcagtagt agattcaacc tcagaaaaag taggagaatt agcagcaatg ctttcaaaag
     1261 gattgctgat gggtgcgcgc ggaaattccg gcgttatttt gtctcaattg tttcgtggat
     1321 tttctaagca aattccagat gttgtctcat taaatgcttc cgatcttgct gcagccttca
     1381 ctcatggagt tgaaactgcg tataaagcag taatgaaacc agtagaagga acgattttga
     1441 cagtagctag agaagcagcg aaagctggag aaaagaaagc aaaaagtact gatgatgtcg
     1501 ttgaagtaat gacagctgtt gtaaaagggg caaagcgtgc tttagctaaa actccagact
     1561 tgcttccagt cctaaaagaa gtcggtgtcg tagacagtgg agggcaagga ctgctgtttg
     1621 tttatgaggg ctttttaagt gcattgaatg gagaattcca agcggatgaa acatatgaac
     1681 cttctccagc agaaatggat gatatggtca atgcagaaca tcatcgcagt gtccaaggtc
     1741 aaatggcgac agaagatatc cattttggtt actgtacaga aatcatggta aaaatcggag
     1801 aaggacctac agtcgatagt acattcgatt acgaagaatt ccgtaactat ttagatggta
     1861 taggagattc tttacttgtg gtcaatgatg acgagatcat caaagtccac gtgcatacag
     1921 aaaacccagg agaagtcttg aattatggac aaaaattcgg ttcattagtc aaaatcaaag
     1981 tcgacaacat gcgcttgcag catgagacga ttttggaaca cgatgaagaa gtgaacgagt
     2041 ttgcgaaaaa agaaacacca cgtatcccgt atggtatcgt agcgatcgct gctggtaaag
     2101 gcgtccaaga gctgtttgaa agtttaggcg ctaattatgt tatcagtggt gggcaaacaa
     2161 tgaatccaag tacggaagac attgttaaag cgattcaaga agtaaacgca gataaagtga
     2221 ttgtcttgcc aaacaataag aacatcttca tggcagctga tcaagcagca gaagtagcag
     2281 atatcccagt agcagttgtt ccttcaagaa cgatttccca aggattgaca gctatgcttt
     2341 cattcaatga tcaagcttct ttagaagaaa acaaagaaac gatgacagaa atgttgtcta
     2401 gcgttgtgag cggtcaagtc actcacgcga tcagagatac ctcaattgac ggtgtagaga
     2461 tcaaagaagg agactttttg ggcatgatcg atggaaaaat cctgatctct aacccagata
     2521 tcacagcaac agcgttaagt acactagaac aaatgatcaa tgaggacaca gagatcgtaa
     2581 cgatcttggc aggtgatgaa ggaacagttg aacaagcaaa tgaatttgct gagaaactaa
     2641 cagaaaaaca tcctgatttg gaaatcgaga tccaccaagg agatcagcct gtctatcctt
     2701 atctattttc tgctgaataa tttctgtgtc agaatatctt tctaacacag tattcattca
     2761 taaaaggcct tcggttagtg atcaggtatg atcgctgacc aagtcctttt tttgttaagg
     2821 gagggaggaa aaatttatgc gttctttaga tgatccaatc actatgctgg caggagtcgg
     2881 agaaaaaaga gcagctagtc ttgccagctt gggcatccaa acgattgaag acttactgac
     2941 ttattatcct ttccgctacg aagatattca ggaaagaaat ctaaacgaga tccaagatca
     3001 agaaaaggtt actttgaaag gaatcgtagt ctcgcctcct gtgatgaatc gatttggtta
     3061 taaaaaaagc cgattgcaat ttcgtatgat gcaagaacat gatgtgttca acgtttcttt
     3121 ttttaatcaa ccttatctaa aagaaaaagt cattttatcg gaggaaatcg ccgtatacgg
     3181 taaatgggat gcaaagcgta aagcattgaa cgggatgaag attttaggtt ctcaaacaat
     3241 ggatgacttt tcgccgatat atcacgtcaa caaatcaatt cgtcaaacga cattagttga
     3301 tctaatcaaa aaagggtttc aagaatacgg cacattgatt gaagaaaatc tgccaaacaa
     3361 ccttgtggag aaatatcgac tgcttgaccg agcttctgct gtaagaagta tgcattttcc
     3421 aaaagaccac gaagaaaacc atcaagccaa acgacgtgtc gtttttgaag agttcttttt
     3481 atttcaaatg cgtcttcaag gattgaaaaa agcagaaaaa gcagaaacga atggtttgga
     3541 gatcctttat gatgtccaaa aattgaaaga atttactcaa aagctacctt ttgaactgac
     3601 aaatgcacaa aaacgtgtaa cgaatgaaat ctgtcgggat cttcgcagtc cgcagcatat
     3661 gcagcgactt ttgcagggag atgtaggtag cggaaaaaca gtggttgccg cgattgcgtt
     3721 atacgctacc gttacagcag gtttccaagg tgcgttgatg gtgcctacag aaatcttggc
     3781 acaacaacat atggaaagct tgcaacagct gtttgatccc aatgaagtaa ccatcgcatt
     3841 gcttacgggg tcaacgaaag caaaagaacg tcgtgagctc cttgaaaaac tagagcaagg
     3901 ggaaattaac atcgtgatcg gcacacatgc attgatccaa gatggagtcg aatttcagaa
     3961 tttaggtcta gttattacgg atgagcagca ccgttttggc gtgaaccagc ggaaagtact
     4021 tcgtgaaaaa ggctggcgac cagatgtctt atttatgaca gcgactccga ttcctagaac
     4081 attagctatt acagcatatg gtgagatgga tgtatctatc attgatgaac ttccagctgg
     4141 acgtatcccg atcgaaacac gctgggtaag aacacctcaa ttggacagtg tactggattg
     4201 gacgaaaaaa gaactggcaa gaggacatca aatgtatgtc atctgtccgc tgattgaaga
     4261 atcagaagca ttagatgtaa aaaatgcagt ggaaatctat gaaaaacttc gtgaactatt
     4321 tgcaccaaaa tatgaagttg gcttgttaca tggtaaaatg aagaatcagg aaaaagaagt
     4381 aatcatggaa gccttcaaag acaaccagat gcagatatta gtttcgacta ctgtaattga
     4441 agtaggggta aacgtgccga acgcgaccgt catgctgatc atggatgcgg atcgatttgg
     4501 attggcacag ctgcatcaac ttcgtggacg tgttggacgc ggaagtgatg cttcctactg
     4561 tatcttagtt gctaatccta aaaatgaact aggtgtggaa cggatgaaaa tcatgacaga
     4621 gaccaccaat ggttttgtac taagcgaaaa agatctggaa ttacgtggtc ctggtgaagt
     4681 atttggcttc cgtcaatctg gtctgcctca atttgcgatt gctgacttgg tgacggatgg
     4741 aaatgttttg gaggtagcca gagaagaggc tgcagccctt tggcagataa aggattggca
     4801 gatgcttcct gagtatcagc ctttagcgca aagcctccaa atagaaaatc aggataatcg
     4861 ttatttcgat tagcagactg tgctatactt tatactgatg acggaaaaag gagtggaaac
     4921 aatgaaaatt gccgtagatg caatgggcgg agatcacgca cctcaagcaa ttgtagaagg
     4981 cgtggcttta gcgcagcaag attttccaga agtagaattc ttactttacg gaaaagaagc
     5041 agaaatcaag aaatacttaa caaatgaaaa aaacatcacg attatccata cagacgaaaa
     5101 aatcaatagt gatgatgagc cagtaaaagc aattcgacga aaaaagactg catcaatggt
     5161 ccttgctgca caagcagtga aaaacggtga agcagatgct gtattttcag cagggaatac
     5221 aggcgcgcta ctagcagcag ggttgttcat cgtaggacgt atcaaaaata tcgaacgccc
     5281 tggcttgatg tctaccttgc cagtagtagg gaaagaaggt gccggtttcg atatgctgga
     5341 tcttggcgct aacgcagaaa acaaaccaga acatttgttg caatacggta ttttaggttc
     5401 tttttatgca cgtaaagtcc gaggtatcgg acgtcctcgt gtcgcactct taaacaacgg
     5461 aacagaagca acaaaaggta gtgaagtgac gaaaaaagcc tatgaactcc ttcagaatga
     5521 aacaagcttg aattttattg gaaacgtaga agctcgtgag ctactcaatg gtgtggctga
     5581 tgtagtggtc acagatggat ttacaggcaa cgctgttttg aaatctattg aaggaacagc
     5641 aatgaatatg atgaatctat taaaatctgc tattctaaat gaagggatca aaggaaaaat
     5701 gggcgctatg cttttaaaag acggcttacg ttctttgaaa gcagaaatgg attattccaa
     5761 acatggcggt gccgttttgt ttggcttgaa agcaccagtc attaaaactc atggagcaac
     5821 aggccccgat gctgttcgct atacgatccg ccaaatccac acaatgcttg agacagatgt
     5881 agttggacaa ttagtcgaac aatttgaaaa aagcgaagaa tagtatttgg atatctgaag
     5941 caatccgttc cattgaaaaa aaggtggaca ttcctgaaaa atgccagtaa aattagccat
     6001 ggtgtaggta attgacaagt gtatgattct tggaggtgaa aaagttgact cgcgaagaag
     6061 tatttaacaa agtagcgaaa attatttcaa atcattttga gatagatacc gataaagtga
     6121 cggatgaatt gaacatcaaa gatgatttaa aagctgattc aattagtatt atggaattcg
     6181 ttttagagct tgaagatgaa ttcggtacgg aaatttcaga tgaagacgct gaacaaattg
     6241 aaacagtcgg tggcgcagta gattatatca gcagccatct taaataattt caaataaaag
     6301 caaagaagga taaaaagctg catacagctt tttatccttc tttttttaat ctttttgaca
     6361 cgtaaaagtc atttttctga taattctggc gataaacaga aattatgttg caaagtaaag
     6421 cgattttcta tataattatt aataattcat tacacaaaga taagaataac ctttgttata
     6481 aaacgcttta ttctgtgtaa tgtccttttt tattaagaaa aacttccatt taggaagcag
     6541 agaggggtat tcgattgtcc gataaccaat tattagaagt tcagaaccta catacaggat
     6601 tccgactcaa agatgactat tacgatgcag tagatgacgt ttcatttact ttagacaaaa
     6661 acgagatttt agcaatcgtt ggggaatctg ggtgcgggaa aagtaccttg gctactacga
     6721 ttatgggatt acttgatcct aataacacaa aaattacagg tgagatttta tataacgatc
     6781 tgaatttaat cgacctgaac gaaacgctct ataataaaat ccgcggaaat gatatcggaa
     6841 tgattttcca agatccgttg tctgcattaa atcctctcat gagaatcgaa gaccagatca
     6901 aagaaggact ttcctatcac acaaagatga atgcagaaca gcgtcaagct cgtgcactag
     6961 aattgctaga acaagtaggg attcctaatc ctgcgagagt tggacgccaa tatccccatg
     7021 aactatcagg cggtatgaga caacgtgtca tcatcgcaat cgcaatcgcc tgcaaacctc
     7081 caatcgtcat tgcagatgaa ccgacgacag ccctagatgt aaccatccaa gcacagattc
     7141 ttgatttact gaaagacctt caggaagaaa caaaaacagg gatcatcttg atcactcatg
     7201 acttaggagt cgtagcagaa atggctgatc gagtggcagt gatgtatggc ggacagttcg
     7261 ttgaagtagc aggtgtaaaa gaactgtttg atcatcctaa gcatccttat acacgctctt
     7321 tactgaactc tataccacaa gaaggaaatc atgatgcaga actccatgtg atcgaaggtg
     7381 tcgttccttc tctgaaaaac atgcctcgta aaggttgtcg gtttgcacca cgtattccat
     7441 ggataccagc aagcgatcat gaagaagagc ctatccttca tgaagtcgca ccgaaccact
     7501 tggtacgttg ctcctgctat aagcatttcc actttagaga cgaaaaagga gaggtgtaga
     7561 tgacagaatt aatcacaatc aaagacctga aagttcatta ccctattcgc agtggattct
     7621 tcaatcgagt aacggatcat gtatatgctg tagatggtgt ggattttatt atcgaaaaag
     7681 gaaagacata tggtttagtg ggagagtctg gctctggaaa atctactacg ggaaaagccg
     7741 ttgtgggatt agaaaaggta acagccggac aaatcatgta tgaaggaaaa gatgtaacga
     7801 agcgaagcaa ccgcaaaaaa atgggttata acaaggatgt gcagatgatc ttccaagatt
     7861 caatgtccag tttgaatcct aaaaagcgag tgttggatat cattgctgaa cccatccgaa
     7921 attttgaacg gttaagcgat caagaagaaa agaaaaaggt aaaaggactg ctagatatcg
     7981 ttgggatgcc ggaagatgcg ctatataaat atcctcatga attttcaggc ggacaacgtc
     8041 aacgtctagg agtagcccgt gctgttgcta ccaatccaaa actgatcgta gccgatgaac
     8101 ctgtatctgc tctggatcta tctgttcaag cgcaagtatt gaatttcatg aaacgaatcc
     8161 agcaagaata cggcctcagc tatttattca tttcacatga tttaggtgta gtaaaacaca
     8221 tgtgcgacaa tatcgcaatt atgtacaaag gtcgatttgt agaaatcggt acaagagaag
     8281 acatttataa tgacccgcga catatctata cgaaacgtct gctttcagct attccgcaaa
     8341 tcgatgtaga aaatagggaa agccacaaag aaaatcgacg aagagtagaa caagagtata
     8401 tccaaaacca aaaagaatac tatgatgcga ctggtcgagt ctacgatttg cgtacgatca
     8461 caactacaca caaagtggcg ttgaaagatg gaggtgcaag ctaatgtgga aaacgattct
     8521 gcgacgtgtt ttattgatga tcccgcaagt tattatttta agtgttctga tcttcttatt
     8581 agcccaagcg atgccggggg atccatttac cggtttgatc aatccaaatc aggatccggc
     8641 agtgatcgaa cagatgcgac aagcagctgg cttgaatgac ccatggtatg tccagtactt
     8701 ccgttggatc ggaaatgctt tgcaaggcga ttttggtcaa agtttcttat acaaacgctc
     8761 tgttgctgac ttgatcggcg aacggatcat caacacttta tatctatcga tcttgacagt
     8821 tgtccttact tatttgattg ctgtgcctct ggggatgctt gctggccggt atcaaaattc
     8881 aatcttggat aagattgtcg taatctacaa cttctttagt tttgctgttc ctttatttat
     8941 cttcggcttg atcatgctat ttgtttttgg ttatcgttta ggctggttcc caacaagtgg
     9001 atcacaaaca ctaggtttgc aaggtggatt tatcactcaa tggatagacc gtttgaaata
     9061 tattctgtta ccatcaatta cccaagcatt tttggcgact gccgtcacaa tccaatatct
     9121 gcgaagtgaa gtaatcgatt cgaaatcgct cgattttgtc agaacagccc gttccaaagg
     9181 ggtaccgacg aataaagtat tcagtcgaca tattttccga aatgcagcgt tgccgatggc
     9241 ttctcaaatg gggtatgaaa tcacttcgtt gattgctggt tctgtagtta tcgaaaagat
     9301 ttttggttat ccgggagtcg gaaaactatt tattgattcc atcggccaac gggactatac
     9361 cgtgatcaca tccttagtat tgattttagg aatcgcgacg ctagtgggga cattactttc
     9421 agatatcatc atgagtatcg ttgacccgcg tattcggatt caataaaacc aatcagaaag
     9481 gagaatggat cgatgagtga aaaaaacaat acagcagttc aagaaagtat tcctcctatg
     9541 gggatacgaa tgattgctcg agaatttaaa aaagataaaa ttgctatttt ttcattaggt
     9601 ttgctagtgg ttttattatt agtgatcttt atcggtgcga tgctgaccga tcaagacaaa
     9661 gtgatgtatg ttagtatctt cgacaaatac gctgcaccag gaacagtttc gacacaagga
     9721 caaaagttca ttctgggagc agatgaaggc ggacgtgatg tattaggaca attgatcata
     9781 ggtgctagaa actctgttac gatcggattt gcgatcacga tccttacttc gatcatcggg
     9841 gttggattag ggatcatctc tggctactac ggagggatca ttgacaacat cttgatgcgg
     9901 atcgttgatt ttatcatgat tctaccgatc atgctgatca ttatcgtctt cgtatcgatt
     9961 atttccagat acaatgtctg gtcctttata ttcatcatga gtgcatttta ttgggtagct
    10021 aaagcccgat tattccgaag caagacatta tctgaagcaa gaagagatta tgtcagtgcc
    10081 tcaaaaacaa tgggaaccaa tgattttaaa atcatgttcc gcgaaatcat gccgaatcta
    10141 agttcattaa tcattactaa tttgacgatg aactttgcgg caaacatcgg tatcgagaca
    10201 actttgactt tcttaggttt cggcttgccg gcaaatgtac ctagtttagg tacattgatc
    10261 ggttatgcaa gtaacggaga agtcttagtg aatcggcaat ggatctggtt acccgcatca
    10321 atccttattt tagttttgat gttgagtatc aattatgttg gacaagcatt caagcgttct
    10381 gcagatgcgc gccaacggtt aggctagtat agaagcgaag ggggaaatag gaatgaagaa
    10441 aacgattttt ggatttgcag cgctgatgtc tgctgtcgtt cttgcagcat gcgggggcgg
    10501 aggtacagat acctctggaa acaactctgg aggcaacggc aataacaaag aggaattaac
    10561 ttttccaatt gcaacaaaaa ataatgatga tgcaatcgaa gacggcgaat tagaagctgc
    10621 ggtcgcaacg gacagtcagt ttaaaggatt gttccagtgg gagttttacc aagattcata
    10681 tgatgcagct tttatggctc cttctcatga accgctattt gcaaacgatg acgatttcag
    10741 aatcacagac gacggagctg caacgcttga tctagatgaa gatacgaaaa aagcgacaat
    10801 caaagtaaaa gacaacgtca aatggtcaga tggtgaagat gtaacggcgg acgatgtgat
    10861 tttcccttac gaaatcattg ggaataaaga ttacactggt atccgttatg acgacacttt
    10921 ccgtaacatc gtaggtatgg aagaatatca tgatggaagt gccgacacaa tctccggaat
    10981 caaaaaaata gacgacaaaa cagttgaaat cgaatataaa gaagtaaacc caagcatgct
    11041 tcaatcgggt ggtggtatct ggtcatatgc agcaccaaaa catacgttag aaggtgtagc
    11101 aatcaaagat atggaatcaa gcgatcaagt acgtaaaaat ccagtgactt ttggccctta
    11161 ttacatgagt aatatcgttg caggagaatc agtagaatac ttgccaaacg agcactactg
    11221 gaatggtacg cctaaattga aaaagatcac gatgaaatct gtaccgatgg caagtgcaac
    11281 tgaagcattg aactctaaat tatatgatat gattttccaa atgccaacag atacttacga
    11341 tacctataaa gaaattgctg gctatacaaa cttaggccgt gaacaaactt cttatactta
    11401 tctaggattc aagttaggta aatggaatgc agatacaaag agtgtggaat acaatccaga
    11461 ttcaaaaatg gctgataaat cattacgtca agcaatgggc tatgcattag ataataatgc
    11521 agtaggtgaa cgtttctatg caggtttgag aagcaatgcg acttcattga ttcctccagt
    11581 attccagtca taccatgatg atgagatgaa aggattcaca caagatctag acaaagcgaa
    11641 aaaactatta gatgatgctg gctacaaaga tgtggatgac gatggtttaa gagaagacaa
    11701 agatggaaat aaactaacaa tcaactttgc ttcgatgtcc ggtggggaaa cagcgcaacc
    11761 attggcagat tactatatcc aacaatggaa agaaattggt ttggatgtcc aatacacaac
    11821 aggtcgtctg atcgaattca attctttcta tgataaatta gaaaacgatg atcctgaaat
    11881 tgatgtttac caagctgctt ggaatacagg aactgatcca aatccaagtg gactatgggg
    11941 accaaatgct gcgttcaact acactcgtta tgaatcagaa gaaaatacaa aattgatcaa
    12001 cgatatcagt tcaagcaaag catttgatga agagtaccaa aaagaagcat atcaaaaatg
    12061 gcaacaatat gcatttgaag aagcatttgc gattccaacg ttgttccgta atgaagtatt
    12121 gccagtcaac gaccgtgtca aagactggga ttggtcttat gatgtaccaa acccatgggc
    12181 aaatgtttct gttacagcag attcacgttc ataatcacta aaaatgaccg aaaaagggcg
    12241 atgtcctttt tcggtttttt gatatttttc tgtttatttc tctaatattc aggtcaaggc
    12301 gctgatttca tgacttctcc aataaacggt gttcaaagtc cagtttctcg gtattaagtc
    12361 aaatttatgc aaaaatatgg aaagccattt tcacaaaatt ttttcttcat actcgaaact
    12421 aaacgaattt ttcacaactt ctcgtcaatc actaggatta ttaaagcttt acttaccttt
    12481 tgaccgaacc atttcaaatt tgacaaaaaa ccagtataat aaggaagtat cgaaaaaata
    12541 tccataaaag gaatgtggaa aatggacaac cagctgacaa aagaactaaa agaaaactat
    12601 aacatcgttt ttcacgatct aaatttgctt gaacaagctt ttacccattc atcctatgtg
    12661 aatgagcatc gcaatctgca attatcggat aatgagcgac ttgaattttt aggagatgcc
    12721 gttttagaac tgatggtttc tcagtattta ttccgtttat atcctcattt gccagaagga
    12781 aaattgacaa aaacacgagc tgcgatcgtt cgcgaagaca gcttgtcgaa atttgccaaa
    12841 gaatgtcact ttgatcaata tgttttgttg ggcaagggag aagagaattc aggaggacgt
    12901 acgcgaccag cattgctttg cgacctattc gaagcttttt taggcgcgtt atatcttgac
    12961 cagggattcg acacgaccca tgcattcatc gaaaaagtga tttttcctaa agtcaaagca
    13021 ggtgcttttt cacatgagat ggatcataaa acaaaactac aagaagtctt gcaaaaatca
    13081 ggtgatgtat caatcgaata ccgattgatc aatgaagaag gtccagctca tgaacgagta
    13141 ttttggatcg aagtttatgt agatgatcaa ttgattggca ctggacaagg gaaatcgaaa
    13201 aaattagcag aacaagctgc ggcggaaaat gcattggcag cactgtaaaa gtaagtgagg
    13261 gaaagctttg tatttgaaac gaattgaaat agccggtttt aaatcatttg cagacaagac
    13321 agtcattgat tttgaaaata gcgtcacagc agtggttgga ccaaatggca gcggaaaaag
    13381 caatattaca gaggctatcc gctgggtatt aggagaacaa tctgctaaaa gtctgcgagg
    13441 cggaaaaatg ccggatatca tctttgccgg ttccgatacc cgtaagcagc tgaatattgc
    13501 agaagtcaca gtgattttag acaatagtga tcattatctg ccattggagt acaatgagat
    13561 cagtgtaacc cgccgttatc gacggactgg ggaaagcgag tttttcatca ataaacaaag
    13621 ctgcagatta aaagatatcc aagaattgtt cttagattct ggattaggaa aagaatcgtt
    13681 ctcaatcatt tctcaaggaa aagtagaagc gattttcagt agtaaaccgg aagaccgtcg
    13741 tgggatcttt gaagaagcag ctggtgtctt gaaatacaag cagcggaaaa agaaagcaga
    13801 acagaagctt tttgaaacag aagacaacct cagccgcgtc caagacatca tccacgaatt
    13861 ggaagaacag ttaactcctt tggccgccca gagtgaggca gcaaaggagt ttttacggct
    13921 aaaagaaaca ctgactcaaa ccgatgtctc tttgatggtt gctgaaatca agacagcaaa
    13981 aaaagattgg gacaacaaac aagcacagct tgcgaaattc aatctagaat taggcaaact
    14041 atctgagtcg atccaagaac aagaatccat tttggcgaag cagcgtaaag aaaatgcgca
    14101 agccgatcgt ctgatcgaaa aaaatcagca agtattatta gatctttcgg aaaaactgaa
    14161 gcagacagaa ggacaaaaag atgttttgca ggagcggaca aagcatacac aaaaaagctc
    14221 gcaagaatat caaacttcat tagcagaagc acaaaaaaag gttaaacatt ttgaaaagct
    14281 tcaagaaagc ttgatgaaag cagcagcaga aaaagaaaca gagatccaaa aagctgaagc
    14341 aaatctcata aaaacacagc aagaattaga aaaataccaa aaatcaacga aagaattatt
    14401 ggcagaatta agagatcaat atgttgattt gatgcaagaa caagcagctg taggaaacga
    14461 actgaagtat ctagaacgtc aatatataca agaaacagca aaaagcaagc agacgttagc
    14521 caagcaatcg gaagtagaag catcagtaga ccgattgatc ttacaaaaag aagaattgac
    14581 acaaaagcag gcgcagctaa aatcatcttt aactgaaaca aaagagaagt tagaaatgat
    14641 ccaacaaaac gggaaaaagt tccaagaagc attagcaaaa gaacagccta aaatgtatca
    14701 attaatgaat caagtccagc agctacgtgc tcgtaagaaa agccttcaag aaatccaaga
    14761 aaactatttt ggtttttacc aaggggttcg attggtcttg cagcataaac agcagctttc
    14821 gggtattgtc ggagcagtgg ctgaactgat cgatgttcct gcagatttca cgttagctat
    14881 cgaagcagct ttaggtgggg cagcccagca tgtcatcgtt gaaaatgaaa aagatgctcg
    14941 gcaagccatc acgtatttga aacagcaaag aggaggaaga gcaacattcc ttccactgac
    15001 gacaatcaaa ccaagacaat taccggctca tatattgaca caagcagcag ctgtagaagg
    15061 gtttataggg attgccagtg aacaagtcag ttatcccgat caaatccaaa ctgtggttca
    15121 aaacctgcta ggaacgatcc ttttagccaa agacttaact agtgccaatg caatcgcgca
    15181 aacgatccgc tatcaatatc gagtggtttc cttagaaggt gatgtgatga atgccggagg
    15241 atccatgaca ggtggagcga ataaacgagg aaaccaaggc agtttgtttg tacaaaatca
    15301 agaattgaaa cagttgacta gtgaatttga agaagcagat aaacaactcc aagcacaaga
    15361 aaaaaaagtt caggagctgc aacaagaaac agctcgttta gccgaagaac aagaagtttt
    15421 gcgtacacga ggcgaacaat tacgttttga agaacaagaa gcgacaaatc agctacaaaa
    15481 catcataaat gaacttgaac gttttgaaaa agaaaagcaa atctcaactt ttgagacacg
    15541 tgaactgcag cagtttatcg aagattacga aaagcaaacg aacgaattga aagacaaaca
    15601 aacagatctt gaatcgcaac gacaaaaaat cgacgaagaa atcaaatcgt taagtcaaga
    15661 aagcgaccag atggaagcca gaagagcaca agtacaaagt caaaaagcac aagaacaagc
    15721 agatcttgct gtcttgaaag agcagtttaa tcatctgcag atccagctcc gcggtgcccg
    15781 agtccaaaaa gcagaggcaa ccgaacgtca agaagcgata gaaaagcagt tggcgacatt
    15841 gacagcagac ttttctgatc atgaagtcac agaagaaagt ttggaaaaac aaattaacga
    15901 attatctgct cagcgagaaa cattaaaagc cgagttggca aaagccaaag agcagcgaga
    15961 tagaaggcaa aaggagatcg ataagcttga agcagtcttg gcagagcgta atcgtgagca
    16021 aaaagcacga ctgtcggaac aatccaaatt agaagtccaa aaagaccgag ctgaaatgat
    16081 tttagataat catttgacct atctgcagtc agaatatcag ctgacatttg agaaagcttc
    16141 ccaagactat caagaaacaa ccgatatcga agacagtaga acaaaggttt catccttaaa
    16201 agaacagatt gaaaaactgg gaccagtaaa cttaaattca atcgaacaat acgaacaagt
    16261 cagtgaaaga catacattct tagcaacaca gcgagatgat ctgttagcag cgaaaaacca
    16321 attgtttgaa acgatggatg agatggatga tgaagtgcgg acaagattca aagaagtatt
    16381 tgaagctatc cgtcaagaat tcaaaattgt ctttccaaat atgtttggcg gcggtaaagc
    16441 tgaattagta ctgacggaac caactgattt gctgaaaaca ggtattgaga ttgaagtaca
    16501 acctcctggc aaaaaactgc aaagtctaag tttgctttct ggaggagaac gagcacttac
    16561 agccatcgcg ttgctctttt ccattatccg tgtctgtcct gttccgtttt gtatcttaga
    16621 tgaggtagaa gcagcgttag atgaagccaa cgtgaaacgt tttggtcgtt acttgagcga
    16681 tttccaagat gacacacaat ttatcgtagt cacacaccgc aaaggaacga tggtcgcagc
    16741 agatgtactg tacggagtga cgatgcagga atccggtgta tcaaaaatcg tttctgtacg
    16801 gatggaagat atcaatgaag aggcgaaaat caacgaaacg aaagtgtagg aacgaaaatg
    16861 atcaaattag tagcaatcga tttggacggt acattattaa atgaacaaaa gctgatttca
    16921 gatgagaata aacaagcatt agcacaagca aaacagcaag gggtcaagat cgttctatgt
    16981 acaggacgcc ccttagctgc gatggcgcat tatctgcaag aattaggact ggtagatgaa
    17041 ggtgactaca gcatcacttt caacggcggt ttggtacaaa aaaatgatac tggtgaaatc
    17101 atggaaaaga aagtgatgga agtatcagat atccaacgct tatacaaact ggctcagcaa
    17161 ttggatctgc cactagatgt tttgtctgac aatgtggttt tacagctgcc tagtgcccca
    17221 aggaagcaat ccttgtacaa tgtgttgaat aagctgctgc aattccaacc agcggatata
    17281 agcgatatta cagatgaatt tgtgcttaat aaggcagtaa tcgcttatga ccaagaagaa
    17341 ttagatccta aaatcaaaga aataccagca gaattccatg aaatgtatga gatcatcaaa
    17401 acaagaagta tgcttttgga atttatgcca aaaggtgtta caaaagctta tggtatttct
    17461 ttattggcaa aagatcttgg tttgaaacaa gaagaaatca tggcgatcgg tgatgaggaa
    17521 aatgatttac cgatgatcca atatgctgga ctaggcgtag cgatggagaa tgctgtgcct
    17581 ttcgtcaaag aagcagcaga tttcgtgaca gccagcaatg aagaaaatgg cgtagccaaa
    17641 gtgatccaaa aatttgtatt agagtagggg gagtcaaatg ggattttttg ataaaatcaa
    17701 gcgtgctttt actggcgaag agaaaacaga agaagttgaa gtacaggaga agtacgacaa
    17761 gggtttagaa aagacgcgta aaacatttgg tgaacggatg aatgagttgt ttgccaattt
    17821 tcgaacagtc gatgaagact tttttgaaga attagaagaa acacttatcg gtgcagatgt
    17881 aggttttgaa acagcgatac gaatcaccga agcattacgt caagaagtga aactcagaaa
    17941 tgcgaaaaaa tcggcagaag tccaaaatgc gatcatcgag aaacttgtgg atctctatga
    18001 agcggaagga atcaatgaag taaatgaact aaatatccaa gaagacggac taacagttat
    18061 tttgtttgtc ggtgttaatg gtgtagggaa aacaacaagt attggtaaac ttgcccatca
    18121 gttcaaaaac gaaggtaaaa aagtattgat ggcagcagca gataccttcc gcgctggagc
    18181 aatcgaccag ttagttgtct ggggcgaacg cgctggtgtt gaagttgttc gtggcaatgc
    18241 aggaggcgat ccagcagctg tcgtattcga tgctttggaa agagcaaaga cagagcaggc
    18301 agatgtttta ctagttgata ctgcaggccg actgcaaaat aaagtgaact tgatgaacga
    18361 attagaaaaa ataaaacgag taatccagcg ggaattacca gaagcacccc aagaaacact
    18421 tcttgtatta gatgcaacca ctggtcaaaa cgcgatggtt caagcaaaac aattcaaaga
    18481 aacaacagat gtgaccggtc ttgttttgac aaaattagat ggtacagcaa agggcggtat
    18541 cgtacttgct atccgtaatg aattgcattt accagtgaaa ttggtcggtc ttggtgaagg
    18601 aatcgatgac ttggagccgt ttgatccaaa tgattttgtc gttggattgt tcaaaggatt
    18661 actaaaagaa gaataaccca tgtctaaaaa gcaggagctg tgacaaaagt tgcagctcct
    18721 tgtttgaatg attgttttta acatagctgt gtttttgatg ccttcatttt tatacttatt
    18781 tgtaagcggt tctcaaacaa tttcgttctt tttcttagac tttttgatta taattagatt
    18841 catatgaatt ggaggtcact taatgatgaa ttttaagcaa ttattattgc atgtcaatgc
    18901 gcgccctttt atcgaccaag ctcgatttgg tatagaacgg gaaggacagc gggttgatct
    18961 tgcaggaaat ctagcaaaaa ccgatcatcc agcaatcttt ggcgatcgat cctatcaccc
    19021 ctatatccaa acagatttta gcgaaacaca aacagagatg atcacccctg ttaccgattc
    19081 tattcccgaa ttatttcagt atctcgctgc tgtttatgat gtgactgctc gttctatacc
    19141 gaaagaagag atgatctggc cattaagtat gccacctgcc ttaccggaaa aagacgaaga
    19201 gatcattatt gcaaaattaa aaaatttcga agatgtcttg tatcgacgtt atttagcaaa
    19261 aaaatacggg aagcgaaaac agatggtaag cggtattcat ttcaattttg aatttggcga
    19321 tgagttgcta agaacattgt tcagccatca ggaagaattt caagattttt ccgaattcaa
    19381 aacagaactt tatttgaaaa cagcgagaaa ctttatgcgc tatcgctgga tgatcactta
    19441 tttattcggt gcttcaccaa tgagtgagaa gaactacttt ttagatgaat cacatccgca
    19501 agaacctgtt cgcagtattc gcaacagtgc gctgggctat acgaatcatc caaatgtgaa
    19561 agtttcctat gcttctatga aacagtattt agcagatatc gagcgaatga tcgaagaagg
    19621 gaaactttcg gaggagaaag aattttatac accgcttcgt ttccgaggcg gaaagaaagt
    19681 cgcagattta gcaacaacag gtgttcgtta tattgaattg cggaatatcg atttgaatcc
    19741 ttatgcaaga ttgggtatca atccagagca agttcggttc ttacaattat tcctgatgta
    19801 catgttatgg acagaagaaa aagaagactg tgaccaatgg gtagcagaag gtacgactcg
    19861 aaataacaaa gtagcactag aacaaccatc agatcaaaca gaatttcatc aagaaggtag
    19921 agaaattctt gaaggaatga agcaaatgct ggttgaattg gattggttgg attctcttta
    19981 tttagtagag gaagcattga ctcaaatgga tcatcctgaa caaacgttag cagcgaaact
    20041 ctatcaagaa gcacagctat cgagtcagca agaagttgct gtggcattgg gacatcaata
    20101 ttataaagaa agccatgaac gtccctatca gttggccggt tttcgcgaaa tggaactttc
    20161 tactcagata tttatgttcg atgccatcca aaaaggtgtc caagtcaaag tattagatga
    20221 gtcggatcaa tttttgcgtc tgcaattcca agaccatgta gaatatgtga aaaatgcaaa
    20281 catgacaagt aaggacagct atatcgtccc acttatcatg gaaaacaaaa cagtaacgaa
    20341 aaaagtctta aaagaagctg ggttccgggt accaggaggc gcagaatttt catccatgga
    20401 agaagcggta aaagcttatc cgagatttgc cgagcaggca tttgtgatca aacctaaatc
    20461 aaccaattac gggttaggta tcacgatttt caaggaagga gctagtctgg aagattatca
    20521 agcaggttta gccattgctt ttcgtgaaga cagttcggtt ttagtagaag aatttatgcc
    20581 gggaacggaa tatcgtttct ttgtgatcga cggagaagtc caagccatca tgttgcgagt
    20641 ccctgctaat gttattggtg acagtatccg aacagtgaaa gaacttgttg aagaaaaaaa
    20701 tagtgaccct ttgcgtggaa cgaatcatcg tgcaccttta gaattgatcc aattaggtga
    20761 attagaacaa ttgatgttga aagaacaagg gttgacgatc gaatcagttc cccaagccaa
    20821 tcaaattgtt tatctaaggg agaactcaaa tatcagtaca ggtggtgatt cgatcgatat
    20881 gactgatgaa ttttctgaag cttacaaaaa aatcgccgtt tctgcggtag aagcactagg
    20941 agctaagatt agtggtatcg atttgattat accagataaa gaaatcgatc ctacaactga
    21001 taaaaaagca tatgggatca tcgaagcaaa tttcaatcca gccatgcata tgcatgttta
    21061 tccttttgca ggaaaaggca gaagattgac gatgaatgta ttgaaattgt tatatcctga
    21121 agtattttaa aagaaaaagc ttttgacaga ttgtcctatt tgatgtcaat ctgatcaaaa
    21181 gctttttttg catgtaaaaa tttatgtgtt ttttcgtttt aaaataaacg atcccagaag
    21241 ctttttttct tttttggttt ttctttttca gctggcgaag agttttcttc tgggtatttt
    21301 ttttcgatat caatcacagg ttcatttact gcttcttttg ctgttaagag caatccgaat
    21361 tcctcaggat ttgcagtgac gtaatcgttg actacagtga aacggctatt gtttttcgtt
    21421 gctagctgga tatattggtt ttggacagaa aggggtagag ccccattcaa gagtatggaa
    21481 gcatctggat gttttttgag ttcttttaaa aagttttctt tgttttttgg ttggatcatt
    21541 tcagcaacag tcatactaag atagcagcgt tccctgaatg tccctaaata tttatgctgt
    21601 tcttcagggt tcactaaagg tgtaccataa agtcccttat ccaaatggct ttttacatca
    21661 tcttgtgcca taaaaaatac cctccttctt ctctttgtct ttcttacgat tatagcatat
    21721 tcccaataat acctaaaaca tatgaaaaag cggttgcttt tgttcaacga ttcacttaaa
    21781 ataagaatga aaatcattct caattagaaa ggtggattgg atgcgctacg gacgactagt
    21841 agcattatta gttattttaa gtagtatttc attgttcatc ggagtatcga atgtacaatt
    21901 gtcagaactg ctccagttag atgggcaaag cttacaaatc ttgctagtga ctcgtttgcc
    21961 acgaacgatt tgtttgatcc ttgtgggagc gaccagtagt atttgtgggt tgatcatgca
    22021 acatttgacc caaaataaat ttgtttcacc aacgactgcg ggcacgatgg atagtgcgcg
    22081 tttaggtatt ttagtggcta tgattttcct acctggtgca tccttgattg tccgatcctt
    22141 gacagcattt tgctttgctt ttgcaggaac attgcttttt ttatccctta cgcgattgtt
    22201 cctccagaaa aatcaattga tgcttccgtt gattggagtc atgttaggga atatcattgg
    22261 ttcagttgct actttttttg cttatcaatt ccagttggta caaaatatga cttcatggct
    22321 tcaagggaat tttgcgactg tgatacgagg aaattatgag ttattgtatg ctgttgttcc
    22381 attgttgctc ttggtttggc tatttgctta ccgatttacg atcattggtc tgggcgaatc
    22441 gtttgcagta aatctgggaa tagattacca gaagatgcag tttttaggca ttggcttagt
    22501 atcattggct agtgcagtca tgttgatcat ggtaggaagc attcctttta tcggagtgat
    22561 cattccgaat cttgtctcta gaatatatgg agatcaagtg cacaaaacaa ttggcgtaac
    22621 tgctttagca ggtagtttgt tcttagtatt ttgcgatctt gtcgctcgcg tgttgatttt
    22681 tccttatgaa ataccagtca gtgtgatcgt tggaatcatc ggtggggcta tcttccttta
    22741 tcttctgata aggggacgac gatatgctta aaaaaaagcc atctattttt attggtatgc
    22801 ttgttcttgt tttatttgtt acaggaatgt acttgacgat ccatacatat ggaaactggc
    22861 attttgcatg tgcattgagg agtaagaaaa tttttgcatt tatccttgtc tcgctagctg
    22921 tcagcagtgc cacaatcagc tttcagacaa ttacgcataa ccagtttttg actccttcag
    22981 tattgggact tgagtcgtta tatgtccttg tccaaacggt ccttttcttc tttatcggag
    23041 gagtgacgat gcttcagcag acaggtacag tttttttctt attgaacgtt gggctgatgg
    23101 tcgggctgag tctattgtta tttttctttc ttttgaaaaa aatgagagcg aatctttttt
    23161 tattactgat gtcagggatg attttaggta cgctttttgg tagtgtcagt acctttttac
    23221 aagtcatcat ggatccgaat gaatatgatt tgcttcaagg cagattattt gcaagctttg
    23281 gcaatatcca gagtcagtat cttttgcctg cttctttgat cattatcggc tgctggtacc
    23341 tgttatttcg atatcgacat gtgctagacg ttttccatct cggaaatgaa caagcagtaa
    23401 acctcgggat agacacagat cgttttgaat ttttgatttt atgttgtgtc agtcttttga
    23461 cagggacatc aacggctctt gtgggtccag ttactttttt agggtttatt gtcgcaaata
    23521 tcagttatcg tgtcttttct acttatcgtc atggtcagct atttatcgga agctttctgg
    23581 tagctatgct gtttctgaca ggaggacagc tcgcagtaga gcagattttc ggctggaata
    23641 caacagtgag tgtcgtcgtt gaatttgtcg gaggaattta ttttgtcaca aaattgattc
    23701 gcgaaaggaa gagtatccta tgattgattt acaaaaggtc aataaactgt accatggaaa
    23761 atcagtggtt aaagatgtac agttaacgat tcctgaaaag aagttgactg cttttatcgg
    23821 tccaaatggt gctggaaagt caacggtgtt gtcgatgatc agtcgtttga taccaaaaga
    23881 tacaggtgaa atctatttag accataacga agtaaaggct tggaaatcca atgaattagc
    23941 caaaaaatta tcgatcctac gacaatcgaa tgaaataaat gtccaaatca ccgtgaaaga
    24001 attagtagaa tttggacgat ttccttatac gaaaggaaaa ttgacgacaa aagacgagga
    24061 aatcgttcag gaatcactgg aacaccttgg gttagaagaa atagcggatc aatcgattga
    24121 cactctttca ggcggtcaac tccaacgtgc gtatattgca atggtgctag cgcaagacac
    24181 ggattatatt ttactggatg aacctttgaa caatctagat atgaattttg cggttcaaat
    24241 catgcagatt ttaaaaaatt tagtacaaga aatcgggaaa acaattgtta ttgttcttca
    24301 tgatatcaac tttgctgcaa gttatgcaga cgaaattgtt gcaatgaaag atggacagtt
    24361 atttacgcaa ggaacgaccc aagaaatgat aaaaaaagat gtattggatg aattatacga
    24421 aatggacata cggatttgtg agattgaagg ccgcagattc tgtctttatt tctaaaacta
    24481 acattaggag agaagagatg aaaaaattag tagtaggtat cttgattcta gcatcatttg
    24541 gtttagcagc atgtggaaat agcaacaaca ccagtcaggc agacacaaaa aaaagcagca
    24601 cacaaactga aactacattg acgataacag atagtaatgg agaccaaatc gaggtgccaa
    24661 ataatccaga aaaagtcgtc gtattcgaca atggttcttt agatacgatg gatgctcttg
    24721 gtgttggaga taaggtagtt ggagcagcta caagcagcct tcctgagtat ctttcatcct
    24781 ataaaaaagt agaatcagca ggtggaataa aagaaccaga cttagaaaaa attaatcagc
    24841 ttcagccaga tctaatcatc atttctggcc gacaaagaga ttttcaaaaa gatctaagtc
    24901 aaattgctcc gaccattttc ctttctttag atgcgaaaaa tccatgggaa tctttccagc
    24961 aaaatgtcac tgctttaggg gagatctttg gtaagcaaga agaagctaaa actcaattag
    25021 aggaattatc tagtgcaatc gatcagacga aaaagaaagc agaagctact gacaaaaaag
    25081 cactagtcac acttgtgaat gaagggcaat tatcagccta cggatctggt tctagattcg
    25141 gtttcatcca tgatttattt ggctttgaac aagcagatga tcaaatcgaa gcatccactc
    25201 acggtcaaag tgtttcttat gaatatgtgc tggaaaaaaa tccggatatc ttatttgtag
    25261 tagacagaac aaaagctatt ggtggagacg acagcaaaga tgatatttct gccaatgaac
    25321 tggtagcaca aacgaatgct ggtaaaaatc agcagatcat ctcccttgaa ccagatgtct
    25381 ggtatttaag cgggggcggt ttagaatcaa tgaaactgat gatcgaagat gtgaatcaag
    25441 catttaaata gcataaataa cagaggatta aactctcata ctatgtaaca ataatgtttc
    25501 ttacattctt aaatagcaag agcctatcct caaagaagtt atcaaaaacc atccgtaaaa
    25561 tcgtattgat gattttacgg atggttttta tttatttgag aaatcttttt tcaacgtgaa
    25621 ttcattatct acatcatacg ggttgattct agaatgggga gtggcaaaaa atagtgtgat
    25681 ccattttttc agcatcaaga tcgcctcctt tgatttgaat caaaggtaca aagcgaaact
    25741 tagataaaac ttaaatttag atatttttat tttgtaccga tctcttcttt aaacgatgtt
    25801 ccatctgctg cttctcggca ataagtccac tagactagaa aatatgagaa gctattttct
    25861 gtccagcgtt cttattactc aaaacaaatc gcagttgtca caatctcttc taaacgatgt
    25921 tccatctgct gcttctcggc aataagccca ctagactaga aaatatgaga agctattttc
    25981 tgtccagcgt tcttattact caaagcaaat cgcagttgtc acaatctctt ctaaacaatg
    26041 ttcaatcagc tgaccttcgg tattagctca aagcactgat ttcacaacct ctatttaggc
    26101 atgtgtctca gcaagcggtt gatagttgat gatctgcatt tttcgataaa aatcggcggg
    26161 aagcttactc caccgtttta gtaattgata gaaataactc tcttctgctt tgattttata
    26221 ctcgcttaat atcaatccaa aactattcgt tttttttgaa gctaattttt tataaatatc
    26281 caatgctttg gttttatctt cattgacaaa gagtgttttt acttcaatat aagaaccctc
    26341 gatattttgt gtttcttcga taaaatagat gttttttata tattccttca tagtgattcc
    26401 tccaaagaag tcttttattt gataagttta ctctaccgaa gagttgttaa taatccgtga
    26461 acaaaaagta attctttttc caatagttgt taaaggtttt ttatttttta tagtattttt
    26521 tgttatttaa gaaaggaata aggttaaaca aataacaggt tgctttttgg gtctttttcc
    26581 gttcaagaaa ctgaacgaag aaaagggaaa gttgtctctt ttgtgataag agaaatcata
    26641 ataaacgaat gacttacttt ccaataaatt gagaacagtc agaaccagac aaattagttg
    26701 catctgatga ataaagtgat tattctatga catgaggtga tacagatgaa attagaagtg
    26761 acaaaagaag cacaagaagt attgaagaat aaattagaag cagacgatca acttttatta
    26821 gatatcgaaa acggtgacgg tccatttgca gaaagccaag tcagttgcca attggatacg
    26881 gcatttcgat tgatcattgt caaaaaagat acacaaacag atctaagtct ttattctgta
    26941 gtggctgata caccagttgg accaatcaaa atcaaagaca gtgcaatact ttacatggat
    27001 gatccatcca cacttgcttt agaaccaact tataatagtt tacaattaaa aggaccaagc
    27061 ggcttgagaa aaggcaactt gcaagttgtt cgaaaagact agagggataa aatgggaaaa
    27121 ttggcgatca tcagcgacct acatgtggac atcaataaat tcggcgaatc agagctgatg
    27181 cagctttggc aagttttgca aaagcacaag atcactcggc ttcatctagc cggagatacg
    27241 gctaataaag tagaccgttg cctagctgtt gtcgaatttt tcgtcaataa aggattatct
    27301 acgacatttc atttcggcaa tcacgagttg gcagatgtgc ccaatgaaca gatgatggac
    27361 cattttccag acccacattt tttaaatgaa cggtatattg ctttaaatga gcagaccgtt
    27421 cttttaggga tgaatggctg gtacgactat cagttttccg aattgaaaga ttacgaggca
    27481 atcgtacgaa tgaagcgttt gtattggtat gatcggttca tccagcgtgg gaaaacagat
    27541 ctcgaggtca atgcagaaat gcttgcagct gcaaaaaatt tgctagacca gctggaagca
    27601 aaaaaacttg aggtgatttt atccactcat ttcgttccta aacgggcatt tatcatgtat
    27661 caatctgctc cttatgagcg ttggaacaaa ttaaatgcat ttttaggatc agaatcattc
    27721 ggagaattac ttgaccgtta ttcaaatatc aaacaagtag tttttggcca tacgcatcgt
    27781 cgctttgaag ataaatccat cggtcacacg atttacagct gcagaccttt tggttattat
    27841 tatgaatggc agctgacccg agattttgtc ttgaaagaac agttgctaga cagctatgat
    27901 cctatgaaat tacgtgtcct cttgcgtgcc catcacccag cttttcaggc ctatcaaaca
    27961 caacatttgc aagaggaatt tgaacaagcg atgacaatcg ttccgtattg agacagcatt
    28021 agtaatgtgt aaaagaaaat accttgtaaa acataaggat aagtaagagc agtagatcca
    28081 tttatcgtgg atatgctgct ttttttgcgg aaaataatca gcgaatgttt atttgatcgg
    28141 atgatttgta actcgcagag tactagatgc aagcgtgtat tctttttttg aacgataatc
    28201 acaaaaaaaa atataatata cattttttat ttaattataa ttaatattga ttgaagtcta
    28261 ggcagtcaag tcacattttg atagatagga gggggactta cgaattattt taaaggctat
    28321 gacagctgta tttctagatt gtgtttgcat caagttgcaa taaaaactag aaatcaaatc
    28381 gggctgataa tcatttataa ctaatcgata cataggacca aatataggtc tatgttcttt
    28441 tatttcataa gtatcgtaaa acagaatttt gctatggatt aatccaatcg actgatatgt
    28501 ttagtaaata aagaaagagg aatgtcaatg atgaaaaaag aaatcgtatt aacagcagca
    28561 atgatgttat tcagcatggt agcaagtacg acttttgttt ctgcaactga agtataccca
    28621 aaggaatata acacagaagg aacgattaca tttgaagcag gagatgaggg tgtaactcct
    28681 cctgttgatc cagagaatcc tgatcccaat aaacctgtcg atccatcaga tcctccaagc
    28741 cctggaacag gaggggcatt atcgattgat tatggatcaa aattcaaatt tgggactcaa
    28801 aaaatttcta ctgcggataa aacgtattat gcagctgctg atgtgatgaa cgatgggtct
    28861 agaaaaccga catatgtcca agtgacagat aggagaagta ccttatctgg gtggaaatta
    28921 agtgtctctc aaccagaaca gtttaaaact gccagtgggg atgaactagt tggagcacag
    28981 ctgaaattta cgaaagggca ggctgtttct ttggttgatc caacatatac gccgcaaacg
    29041 gtgaattctg aattaacgtt gacaccggga ggaaacaata cgttagcaat taatgctaaa
    29101 tcaggaacag gtgtggggac ttgggtctat cgatttggtg caaatgaaaa tgaaaatcaa
    29161 gatgcggtac agctttcggt acccggtaaa tctgtcaagt tagcgcaaca atattccact
    29221 aaattagttt ggacattaga agatacacct aacaactagt ttactgaaaa gaactgttaa
    29281 aaataaatac gtagtcatat tgtcttgcga ggtaatcgag caaaaattgt caaaggctag
    29341 gctaaatttg tttggatacg aatagttcat ctaggaattt aacgatcagg aggaaaagat
    29401 atattgaaaa agaggaggat cgtgctcatt ttaagcagtc tcttagtgac taatatcttt
    29461 ccgatcatag ggtactcttt ggaattgaat cagttggagc atggaaatag aagagacgaa
    29521 gaaagcaaac tcacttcgac attcgacagt ttaatagaat ccaaccagac acaagaaagc
    29581 agtgaggatt taagtatttc gagtagtgga gagaccactg acaacgtaga agctgagggt
    29641 tcggacaaac aaggactaga agatgcacca atttctgcgg ttgagctgcc tgacgatccc
    29701 aatattattt ctatcgataa aatttttcaa acacctatcg gtactagcac gtccatattg
    29761 gaaaatggga agttactgca gttgaaccca gcagaaaggt ctcaaagagg agctatttgg
    29821 tcaaataaga agattagttt actctcggat tttacattta aatcttattt atacttagga
    29881 aatcaacgag atagagcggg agatggcatg acctttacat tgactggcga tcctagaatg
    29941 gctagtaatc ccagtcaagt tattggatcg ccaggtatgg gaattggctc atattctact
    30001 cgttctggcc aaccttacat tgcgaatgcg ctctcgattg agtttgatac gtataaaaat
    30061 agtggttctt ctgatcgaat ggatcgagag ataactgctg ataatagagg gcatggacat
    30121 gtcgcttttg tcacgcctaa accaaataat aataattatt ctggagagca tactggcgtg
    30181 acggtagctc ctacatttct ttctaatggc acatggcgct tgttaataat taaatgggac
    30241 gcggagcaaa gaagtcttac ttatgatttg gaaggtgtcg gtcgctcttc tcggattata
    30301 cctgatctca ttaggcagtt tggttctaca gaagtaaatt gggggtttac ttcttcaaca
    30361 ggtacttttt ttcaagaaaa tgctgtcgct gtcacgcgac ttccatcgaa tgtcacatca
    30421 acagctgatg taaaagtcaa cgatagtgat tatggggcca tcgctgaagc tggaggaaac
    30481 gataagataa ctatcagaaa tacattgaag gtcgaggggg attttcttga atataagaaa
    30541 atgcagacta gtatcgacct cccacaagaa ttaactattc ccgagcatat cttgatcaat
    30601 ggaaatcaaa ttgatgccaa agatatcttg ataaccggaa atcgagtcac gctaaatctg
    30661 acagattatt ttattgctgg agatacgtta ataatcgaat tggagacaac tttgcaggaa
    30721 gtaattcctg aaaaagtact cactatgcat tttgaatacc ttgaaaacgg gaatttgatt
    30781 gagcaatcga atgaaataaa cctaaagatc gcaaagctga aggagataga tatccatgtt
    30841 tattataaag ataaagacag tcagattgat attgctgaaa tgaaaacaat cactgggaaa
    30901 ataggagaga agtataaaga aactcctatt gatattgaag ggtatgtttt tgactcggat
    30961 tcagcgaata cagaaggcat cttctccgaa aatacagagg atatctattt ttattacaga
    31021 aaaggcaaac tttatctctc aactgctcct caatatgtca attttggaaa acataaaata
    31081 tccagtagac cattaagtga attcggacag ttttcaggtg ggttgaaaat tatagatgaa
    31141 cgggcttttg gaagttggaa attacaattg aaacaagaga aagttcttac aaatggagat
    31201 tttgagcttc cagaagctct ttcctttgtt acctctgaaa atacaacggt tatagggaca
    31261 tccgctgtta cgattttcga aagtgatcaa aagggtgaaa gcgatttgtc ctctctttta
    31321 gattctacag ctcatcgtgg aatcagaata aatattcctg tagaaaacca aagaatcgga
    31381 acctttgagg ggaaactatc ttggatactt gcagatgtcc caggaaatta acaggaagag
    31441 aagaatataa caaaattatt gagtttcaag aagggcacag gtaccatagg ctcttgtgtc
    31501 ccacagagac aagattttgt tatagtcttc tcttacatat gattaaagga gcgattttct
    31561 tgagaccaaa acaacaatta tttataacac tcctagttat tttaggggca ctttttaaca
    31621 atatatcagt gtcagctagt gcatttaatt tttcagtgac gccgataact tcagagaatc
    31681 aaatcgacaa gagaaaaact tacttcgatc ttcaacttga tccggatcag gaagtagaag
    31741 taaaagcgga attgagaaat gatacagaaa aagaagtgaa aatcgatatt tctgtgaata
    31801 gcgcaaccac caattcaaat gtgatggttg aatacggaaa aaacgagatt gaaaaagaca
    31861 tgagcctgat ctttgatctg gtagattatg tgagctatcc acagatagtg acgctaaaac
    31921 ctaaaagtgt ccaaaccgtt gcttttcatg tcaggatgcc gaatgagcga tttgatggtg
    31981 tattggctgg tgggatcaca ttccaagaaa tccagacgga aaaggaccaa acagaaacta
    32041 aggatcaaag cttatcgatt gagaatgaat acacctatat tattgctttg ttgatgcaac
    32101 agacactgaa cgaagttgct ccgaacctta ctcttcatga agttaaacca gatcaaatca
    32161 atgcaagaaa tgtcatctta gcaaacgttc aaaatgatca aaaaacctat atcaatcaag
    32221 tagttattga aacaaaaatt acaaaaaaag gacattctga agttttatat caagaggaaa
    32281 aagaaggatt gcagattgcg ccgaatacaa atttttcttt tccaactgct ttaaatggtc
    32341 aaccgctaac cccaggtgaa tatcacctta caatgactgt tttaggaaat gaaaatgaaa
    32401 atggaaaatt ttcgagaaaa aaaggaaata ctacgatcaa ctataccaat caatgggtat
    32461 ttgaaaaaga ttttacaata gacggaaaag tagccaagga attgaacacg acggatgtta
    32521 cgattaaaaa agacaataat tggatttata tcttagtagc ttcacttttc ttattgttta
    32581 ttttattatg catacttttg tttgttttga gaaaaaaaga agagaaagaa aagtaaggtt
    32641 aagataacaa atagtaaatt tttattattg taggatggtt gggctctttt tataacaata
    32701 taaaatatac cattttatta ataaaaatgc atactagtaa atgatataat tctaataaca
    32761 ggtttgatcg cgagaaaggc caaataaaac gctctccaaa atgttaaaaa aaagacagga
    32821 cgatgtatat tatacaaaca agaatcgctg acaacagtga ctcggatcca ggaaatcagt
    32881 tttatcccca gctagttggt gaatgcatgg aaagtaatat acgtagaaag agctgatgac
    32941 taatgaatta tgagtttttt ttaagcaaag aagatcacag aagttattca ttacttaaat
    33001 atttagaagc aagctcaaat ttatcagagt caatatcgaa tgttcaagaa gagttgtcgc
    33061 tatcgacatt tctcttgaaa aaaacgatcg ataagctgaa acatgattta caaaagttcg
    33121 atctagagaa aaatttgcga gtaaccgtca gtgaattgga tatatgtctg gaaattaatg
    33181 gaaaatgttc tagcaaagct ctgttatctc gttatataac ggattcttta tctatgaaaa
    33241 tggtattggc tttctttcag gaaaaatata tctcagtaga aaattttgct aaacagcatc
    33301 acgtgagtta ttctgtggct tataaagtat tacaaagact aaaaagaaat ctaaaaaaat
    33361 atcaaatttt ttttgaaaag agaaagtt
//
LOCUS       DAFLWZ010000025        33305 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000025 DAFLWZ010000000
VERSION     DAFLWZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.025"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            125..1552
                     /locus_tag="L1V38_001241"
     CDS             125..1552
                     /locus_tag="L1V38_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315802.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1644..2009)
                     /locus_tag="L1V38_001242"
     CDS             complement(1644..2009)
                     /locus_tag="L1V38_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1315803.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2006..2371)
                     /locus_tag="L1V38_001243"
     CDS             complement(2006..2371)
                     /locus_tag="L1V38_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1315804.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2563..2811)
                     /locus_tag="L1V38_001244"
     CDS             complement(2563..2811)
                     /locus_tag="L1V38_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315805.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2810..2938
                     /locus_tag="L1V38_001245"
     CDS             2810..2938
                     /locus_tag="L1V38_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBN1315806.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2995..4689
                     /locus_tag="L1V38_001246"
     CDS             2995..4689
                     /locus_tag="L1V38_001246"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBN1315807.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4693..4812
                     /locus_tag="L1V38_001247"
                     /pseudo
     CDS             4693..4812
                     /locus_tag="L1V38_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4789..4962
                     /locus_tag="L1V38_001248"
     CDS             4789..4962
                     /locus_tag="L1V38_001248"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315808.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5340..6473
                     /locus_tag="L1V38_001249"
     CDS             5340..6473
                     /locus_tag="L1V38_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBN1315809.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6504..6824
                     /locus_tag="L1V38_001250"
     CDS             6504..6824
                     /locus_tag="L1V38_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBN1315810.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6853..7317)
                     /locus_tag="L1V38_001251"
     CDS             complement(6853..7317)
                     /locus_tag="L1V38_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315811.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7449..8702)
                     /locus_tag="L1V38_001252"
     CDS             complement(7449..8702)
                     /locus_tag="L1V38_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1315812.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8731..9048)
                     /locus_tag="L1V38_001253"
     CDS             complement(8731..9048)
                     /locus_tag="L1V38_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1315813.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9074..9394)
                     /locus_tag="L1V38_001254"
     CDS             complement(9074..9394)
                     /locus_tag="L1V38_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1315814.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9858..11273)
                     /locus_tag="L1V38_001255"
     CDS             complement(9858..11273)
                     /locus_tag="L1V38_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1315815.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11290..12606)
                     /locus_tag="L1V38_001256"
     CDS             complement(11290..12606)
                     /locus_tag="L1V38_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1315816.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12756..13454)
                     /locus_tag="L1V38_001257"
     CDS             complement(12756..13454)
                     /locus_tag="L1V38_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBN1315817.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13743..14699)
                     /locus_tag="L1V38_001258"
     CDS             complement(13743..14699)
                     /locus_tag="L1V38_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1315818.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14812..15645)
                     /gene="msrA"
                     /locus_tag="L1V38_001259"
     CDS             complement(14812..15645)
                     /gene="msrA"
                     /locus_tag="L1V38_001259"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1315819.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15820..17454)
                     /locus_tag="L1V38_001260"
     CDS             complement(15820..17454)
                     /locus_tag="L1V38_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315820.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(17441..19309)
                     /locus_tag="L1V38_001261"
     CDS             complement(17441..19309)
                     /locus_tag="L1V38_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315821.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            19275..20912
                     /locus_tag="L1V38_001262"
     CDS             19275..20912
                     /locus_tag="L1V38_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315822.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(21057..21797)
                     /gene="truA"
                     /locus_tag="L1V38_001263"
     CDS             complement(21057..21797)
                     /gene="truA"
                     /locus_tag="L1V38_001263"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1315823.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(21988..22623)
                     /locus_tag="L1V38_001264"
     CDS             complement(21988..22623)
                     /locus_tag="L1V38_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBN1315824.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(22770..24011)
                     /gene="sstT"
                     /locus_tag="L1V38_001265"
     CDS             complement(22770..24011)
                     /gene="sstT"
                     /locus_tag="L1V38_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBN1315825.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            24209..25207
                     /locus_tag="L1V38_001266"
     CDS             24209..25207
                     /locus_tag="L1V38_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315826.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            25220..27238
                     /locus_tag="L1V38_001267"
     CDS             25220..27238
                     /locus_tag="L1V38_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBN1315827.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(27298..28014)
                     /locus_tag="L1V38_001268"
     CDS             complement(27298..28014)
                     /locus_tag="L1V38_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1315828.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(28241..28783)
                     /locus_tag="L1V38_001269"
     CDS             complement(28241..28783)
                     /locus_tag="L1V38_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1315829.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(28788..29015)
                     /locus_tag="L1V38_001270"
     CDS             complement(28788..29015)
                     /locus_tag="L1V38_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1315830.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(29094..30974)
                     /locus_tag="L1V38_001271"
     CDS             complement(29094..30974)
                     /locus_tag="L1V38_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1315831.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(31163..31777)
                     /locus_tag="L1V38_001272"
     CDS             complement(31163..31777)
                     /locus_tag="L1V38_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1315832.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            31919..32479
                     /locus_tag="L1V38_001273"
     CDS             31919..32479
                     /locus_tag="L1V38_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1315833.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(32784..33098)
                     /locus_tag="L1V38_001274"
                     /pseudo
     CDS             complement(32784..33098)
                     /locus_tag="L1V38_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
BASE COUNT        10510 a         6486 c         5402 g        10907 t
ORIGIN      
        1 acataaaaaa ccttttttaa cggcatttat atgctttttc agaaattaac tgatgatttc
       61 aaaaagaaaa catgtcataa tatttcccat attgtgcaaa aaaatacaag gcggaggctc
      121 tactatgatt gaagaatata ttgagaaaaa tattttaaga cagctgtttt tatgtgggca
      181 attctatgta aataaagaag tcaatctaga aaagctctcc aatctcctgc atgtttgcaa
      241 aaccacttta ctcaatgata tcaataacat aaaaaaagaa tttgaagaac agatcgctta
      301 tacacatcgg gaaaaggacc gttacacttt atatttttca gaacatatac ctcgatgcaa
      361 gatcatgcag caattgtctc aaaattcgtt gtttttaaaa acttgtctgc tttatttgga
      421 agaagatgaa cctgattatc ttcaattaac tgaatgtgaa ttcatctctg tcagcaaagc
      481 ttattcatta aaaaaacaag tattagctta ttttaatgac tgcgggatcg aaatcgaccg
      541 ctactcccct cgattcactg aaatggaaag acgtctgctg cttcttaatg tgtcgtatcg
      601 tttaggcggt tttaattctt gggagctacc tgaatcgttt tttgaacgtg ccgatcgttt
      661 cattgaatcc gtaacggaaa atagtggcag attttatgat aaagaaaata aagaaatctt
      721 atcgattggt tttgctatca gtttcctacg ccagcaagtg tgtgctgtga caatagattc
      781 aaaatttatc gaagaaatca aaaaacgtcc tatttacaat tatgtcgaat cagcatggga
      841 aaacactgat ttccaaacct attataaaaa agaagaattc gcctttattt tgacactatt
      901 caatctttgt aattatggtt tccattctta tcagttgatt gcggaagact ttcaacagct
      961 acaccaagtg tttattgaca atactcccga aataaaagaa ctagttgcta cctttgaatc
     1021 tcacttcaat caagaattat tcggaaacca accgttcgaa cgtgcgctga ttcatctgat
     1081 gcgttcggct tgggataact atcaattatt catgccagaa aaattttatc ttttaaatga
     1141 ggaacagaca aatttatata aagaagtcca gacaattttt tccagctggt ccagccagtt
     1201 accttatgat ctacggttga atcctaattg catgcgggct tttgtgatcg aattgagcgg
     1261 aattctccgt ctgacaaaag aacatctgac tatctatatc gtcacaaatt cggatgttca
     1321 ttatctgatt tatcgggaag ccttggaagc tgtaactact ttcgattttc aagttgcacc
     1381 aacaatttat tcaagtatat ctgatataaa gaagtatgcg cagcagtcct caaaccgggt
     1441 attatgtgaa cgtacattat atacaccaga tgcggtccaa tatgaaaata ttattcctat
     1501 ttcgatcaat acgatcgatc gagctatcat ttcagctgtg caaaacaaat aaggggctgt
     1561 gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc ccatttctgt aacaatctct
     1621 tgatacacgt caggctcaca acctcactta ttttggacat ctacgggtcc gatctcttta
     1681 tttaaaaaat aagaaatgat ggttcggata actaccaacg ccgctagttg gaaaatatcc
     1741 tgcaaggtag gtttgataat cgattcgatg atcccagctg aaacaagaat ttccaaactt
     1801 agaagtatat agcctcccaa catcttttta atagcattgt tctcgctgac tcggtcgctt
     1861 tgcacttttg tatggacaaa taaatatttc aaaaaatcct tgattgatag acaaacaccc
     1921 caaaccaata aacagatagc aaagatatca agtcccagta caagtttttc gaaatatgga
     1981 agaagaaact gcatcaactc tgtcgtcatc ctacctctcc tcttctttgt ttttctttgt
     2041 cttctatttc ctgattcaag aaataagaaa tgactgttcg aatgataata ataagtgcaa
     2101 gcttcaaaat atctgtccaa gtcggcttga taactgactc gatgatatca gcaacgacta
     2161 gtacttccaa gcttaacaaa atataacttg ctagcagttt tcttgtatct gcattacgag
     2221 tattacgttc tgcatagttt ttcttgacat gagaccaatc aaaaagtttg aatagaacaa
     2281 gaacgatccc gacaattaag ataccgatag aacaaatatt taaaatagca atgatccatt
     2341 ctagaaattc aattaaattt gagcgaaaca tatacgctac ctactttctt ttaatttgtt
     2401 cctattcttt tattgtaaaa gaaagttacc ttgttcgtct atttaaaagt tgttctaatg
     2461 ataacggttc gcttaaattt ttctttttca ctctcccatt tttctccctc catccataaa
     2521 tcgtggaagt atccaaaaca acgtagcaag ttaaaataag gcttagtccg tcatcagctt
     2581 ttcaaagaag cactgtctcg gtgctttttt tgtacccaaa tttctaaaaa tagaaccata
     2641 cacctcctca aatcttttct tcttacctac cctattttta tttacaggaa aatcagacac
     2701 ttcttctttt ttgtcaaaat ttcctttttc ttctcgtcct atcatttggc attctaataa
     2761 aaacgaacta tccttggata tagaaagaga aaacaaggag gcgtttttca tgagtaaaaa
     2821 attaatcaaa gtcggcatcg gtttaggttt gcttgccctt ggcgctgcat atctaggaaa
     2881 aaagacagga ctattcgaag atgacagtca tttatatgat gaattcgaat caatctagca
     2941 tcctatttag ttgaatcact acggacatac ttggaagaca ttggaggaat cacaatgaga
     3001 aaaagtaaag caataatgat tggtgccggt attgccaata tggcagcggc tgtttatttg
     3061 attcaagaag gcaaatggaa aggggatcag atcacctttt attcattgga tgatcacggt
     3121 tcaaatgatg gtgcaccgac cgacactgta gtggatgaat attggaataa aaaccatcca
     3181 ttagaaaacc aaaaaggcta tattgctcga ggcggtcgca tgcttaatta ccgtacctat
     3241 gtagatttga tggatctgtt aagtcgaata ccttctgtta ctgagccagg gatgactgct
     3301 gaagaagata cgagagattt tgatgcaaaa caccgaacct ttgacaaagc acgtttgatg
     3361 gaaggtggca aaggaatcat tgatggcgga aaactgggat tcaataataa agaccgtatt
     3421 cttctgacta aactgattgc tatgcctgat tcagaagaag aaaaactaga caatatcact
     3481 atcgaagaat atttcaaaga tgatccacac ttttttgaaa caaacttctg gtttatgtgg
     3541 gaaacaacat ttgctttcag aacacgtagt tctgctcaag aattgcgtcg ctatatgcat
     3601 caaatgattt atgaattcac tcaaatcgaa catctagtgg gcgtcaatcg aacacgttac
     3661 aatcaatacg aaagtattat gcttcctttg atcgagtact tgaaagaaca aggatgcaaa
     3721 atcattttga accgccgtgt cactgactgg gaattcaaag aaacaccgat gcaagatgaa
     3781 atcactgtga ctggtttgaa aattaccaat acactgactc aagaagaaga atacgttgtg
     3841 gtcgatgaag atacagcagt tattttcact aatgggtcca ttacagattc agctacttta
     3901 ggagattacg aaacaccagc tgtagaaaat atggattatg gtgcagcttc tagtctctgg
     3961 aaaaaagcca gtgaacgttt ctacaacttg ggaaatcctg acaaattctt tgctgatcga
     4021 gatgcaagcg aatgggtcag ctttaccctg acgacgaaaa accatttgtt gttgaatgaa
     4081 atcacccgta tcacgactca agaaccagga aatgccttga attcatttat ttcaaccaca
     4141 ccgatcacgc cgttaggcca aaaagatgtc aatatgtcta ttgtcgtgca tcatcaaccg
     4201 cattttacgt ctcagaaacc aaatgaaaca gttatttggg gttatttcct ttatccaaga
     4261 cgacgtggcg aatttgtgga taaacagtat attaaaatga atggaaaaga aatgctagaa
     4321 gaactgattg gacaactttc aaaagtagat cctggaccag tgaatattcg tgaaaaagaa
     4381 acagaaattt tcgacagcgt aataaataat atccctgtct atatgcctta tgcttccgcg
     4441 ttgttcaata atcgtgccaa aagcgatcga ccaaaagtca ttcctaaaca ttcgaccaat
     4501 ctggccttta caggagaatt tgtcgagcag ccttatcaga tgatctttac tgaacaaagt
     4561 gctgtacgtt ctggagaaat cgctgctttc cattttgcgg gtattcctat gtcccgtctt
     4621 gtcaaaacac cgcgttacga caaagatatt cctactctag ctcgtgccgc aaaaaaaatg
     4681 tttgaataat caagaggttg tgaaaaagct gccctgcatc aagtaataag aacaaccagg
     4741 ctaaaacagc ttcttatgtt tttgatttgg ttggacttat taccgcagat gcaagctttt
     4801 gaacaccgtt taccaagagg ttatgaaaaa gctgccctgc atcaagtaat aagagcagcc
     4861 aagctaaaac agcttcttat gtttttgact tggttagact tattaccgca gatgcaagct
     4921 tttgaacacc gtttaccaag aggttatgaa aaaggcgttt agtttcgagt atgaagaaaa
     4981 attttgtgaa aatggttcct cacgtttttg cataaatttg acttaatacc gagaaactga
     5041 tcccttctgt cataacctct ttttatttat gtctgtttct ttttgaaaac aactattttt
     5101 tcaacgttta ctctcttgcc aatccaacat catctaacgg atacaactat ttcaatgatt
     5161 accattacac taaaaaatcg gaaacacacc tctccgaaca caaatacata agactataga
     5221 atgtttcatt taagaaaaaa agcgtttcat tatcaaaaag gtaagatctc ctttaaaatg
     5281 aaattatctg tagtactaat aatgcagaca attttatgaa tctgaaagga gcatctccaa
     5341 tgaaagcagt cacttggcaa ggaaaacaga aaatggaaat cagaaacgta gatgatccaa
     5401 aaatattaga accaacagat gcaatcatcc gtatcacagc aacagccatt tgcggctccg
     5461 atctgcatct ttaccatcat ggtgaagcag ttttggaaaa agggtatgtt gtaggacacg
     5521 aaccaatggg aatcgttgaa gaagtgggat ctcaagttca aacattgaaa aaagggcaac
     5581 gtgtggttat cccttttaat attagttgtg gtcattgtca tttctgcctg aatcacatgg
     5641 aaagccaatg tgatgaatca aatccagatc agttatatgg cgggcttttc ggatttggca
     5701 agttgaacgg taatcattgg ggtggtcaag cggaatatct aagagttcct tatgcagact
     5761 ctacttcatt tgttgtacca gataatgatc ttcctgatga aaaagtttta tttctatcag
     5821 atattttgcc cacagcttat tggagcgttg aaaacgcagg agtaaaaaaa ggcgatacag
     5881 ttgtgattct aggttctggt ccagtcggtc tattcgctca aaaattcgct gttatggctg
     5941 gagcagagcg cgtaatcgca gtagatccag tacagcaccg tctagataaa gcggctaatt
     6001 acaatggggt tgaaacttat ttcttagaag acacggcaca agctggaaca gaattgtatg
     6061 aactggctaa aggtggcgca gatgtcatta tcgattgtgt aggaatggac ggattagagc
     6121 ctgtcaaaga aaaagcgaaa aatttagtaa gcttacaaag cggcacaatc tctccattac
     6181 agatggcatc gcaagctgtc aaaaaatttg gaacagtcca agtaactggt gtttatatga
     6241 ctccagcttc ttcttacccg ctgcaagaat tttttatgcg ggatatcgct gtcaagcatg
     6301 gacaggcacc aattatccat ctaatgccaa aaatttacgc aatgattgca gaaggactat
     6361 tcgatcctac acaaatcatt actcattcgc tgccactatc agaagcagca caagcatatg
     6421 agatctttga caaaaaagaa gataaaaata taaaagttgt tttgaaacct tgaattcagt
     6481 aaaaaataca ggtgattttc tttatgccca aaatcaaacg aaatacccat gagatcgaaa
     6541 taggaaaaga agaagatatc gaaatacgag gacgtcgctt ccgcttctat ttccaaaatc
     6601 gttacacatt gatctcactg gctgtcgatt tattaaccgg gattttctat atttttggaa
     6661 gccttgcttc cttaactaaa atccccgatc gatatggcac ctatttttat ttggctggtg
     6721 ctattttctt gacgattcgt cctattctca gaatcgtaag gaacattttt atttacgacg
     6781 aaaaaaaagc aatgaagaga acaagcaaaa aaaaagaggc atgagaattt ttcaaatctc
     6841 atgcctcttt tttcacccta tcgtatcact ttgatacaga cgagcggtcg tcccactttc
     6901 ttccttgacc attgtcaaaa atgtccactc gtatcgttca taaaacgtgg tatgatctgt
     6961 aattaagtaa agtttttcgt acccaagttg atgcatttct tttctgattt ccgctaatat
     7021 ccgcttggct atcccctgct tacgcttttc cggttcaaca aacagggcac aaagatttgg
     7081 tgtcagatca gggcggttat ggaagtcgtt ttcaatgacg cccgctcctc cgacgatggt
     7141 ttctttttca tctaagacca cataccattg aggaatactt tccttattag cgattccagt
     7201 acgaatactt tcctcataca caacagcagg aactccccat tttgatgaaa accaattcgc
     7261 gctttgtttt actaattctg ggtgttctct taatttgatc cagttatatg taaccaatgt
     7321 ttaaacctcc gactaaaata aaacgtttac aaaaattata caagtcttta tgaaaattag
     7381 caatgacaac aatagtgatg taaaaaaaaa aacggaaaac aatcacttgt tctccgtttt
     7441 ttgattaatc aagcatctaa agcttctttt cttctttctt ggatcgtagc taccttgacg
     7501 aacggtagat agatcaaaat agaaagaacc aaattgacag cggctagtac accacctgca
     7561 atactttttg ttgccaatac accgccaata attggtggag ttacccatgg aggcataacg
     7621 gtagctgctg gcactaaacc tgtagaagtc gcaaagtaag caacactaac taagaccatt
     7681 ggtgtcaaaa taaatggaat gaacatgatc gggttcaaca cgataggtaa cccaaacatc
     7741 gttggttcat taatattgaa gacacctggc gcaatcgaca agtttgttac aaccatatat
     7801 ggtttgtttt tacgtcctac taaataaata gctaacagta aacctaaagt tgcacctgtt
     7861 cctcctaagt tgacaaagct gtcaaagaaa ggtttgttca cgataaacgg tgcgctatgt
     7921 ccagctgcga ttgcattaac gtttgcttca atggctggcg cattgattgt ttgcatcaaa
     7981 ggatcgacca tattcgctcc gtgtaaacca aagaaccata agaatggtgt gataaatgca
     8041 agcagtaagg cagatggata agagtttgca agtcccataa atggttcttg gaccactgta
     8101 tagaaagaac ctacgatatc atcaacaccg aatgcagcaa aaattgcagc aactaaagca
     8161 aacgcagaga tagtgatcat tgctggtagt aatgaagcaa atgcttttgc aactgccggt
     8221 ggcacaccat caggcatttt gatgatcaat ttttcatttc cgcttaaacg tacaaagatt
     8281 tctgttgaaa taatcccaac aataatagca ataaacaaac cgtttgagct catacctaat
     8341 gctccgccta aagcgaagaa agagcctaaa gaaatcacac ctgcggaaac accgtctttt
     8401 cggtagccgt tagctaaatg ataagcaagc aagaaagcaa tcaagacaga aagaatggca
     8461 aatgtaccgt tccaagcagc agccccgaat cctttccatg attcaccacc aaaaattgag
     8521 ttcatcaatt cttggaaccc gggaatcggt aagttattga tcattactgc taatgctcct
     8581 aagatcatta acggcatact caccataaat gagtcccgaa tcgcaactaa atgccgttgt
     8641 gcaccaattt ttgatgctac aggtataaaa tgtttctcca taaatgcaac aaatttatcc
     8701 ataaatcttc cctcttttct ttactgtaga ttacgcgttc aatcgacgat acagatcaat
     8761 gatctctttt gctaaatctg taaaagctat agatgtcatc agatgatctt gactgtggac
     8821 cgtcaaaagc gtgacttcaa cgtgatttcc ttgtgcttct tgtgtcagca tctctgtttg
     8881 agagtgatgt gcttggacta aagattcctc tgcatctttg attttttcat ctgctaaagt
     8941 gaaatcacct tttttcgcag cagcaatcgc ttccattgca tcgctttttg catttccgcc
     9001 aaacatgatc agacccatga tggcttctag atttttttga tcttccattt attgtatcct
     9061 ccgataattt ttattatttg tttattagtt tttctgcttg gtcgagtact ttttcaccat
     9121 tcatcatgcc atagtcagcc atattgatta catctaaagg aatgccttta ggtgctagct
     9181 tttcagcaaa ttgattttgc ataaagcgta cttgcggtcc taaaagtaaa acgtctacat
     9241 ttttagattc tagttgatta tccgcatctg aagcagatac agcaaagatg tctgcttcca
     9301 ttccttttgc ttctgctgcc ttttgcattt ttgtgactag gagacttgta ctcattccag
     9361 ctgaacatac aagcatgatt gttttctttt ccattttaaa cacgttcctt tctatactta
     9421 cacttgtata taagcaagta gcgtgccaac tttaaaagcg ctttaaaaag ttgatatcat
     9481 cacatttaag gtctatacca agttgcatac acactaaaaa agaaagcgca cactaaacac
     9541 acaaattaat ttttattacc ttttttcttt taacgtgcac aaaaaaagtt gtgacacaaa
     9601 acttgtcaca acttttttca aataaacggt attcaaaagc ttgcatctgc ggtaataagt
     9661 ccaaccaagt taaaaacata agatgttgtt tttactttgc tattcttatt acttgatgca
     9721 ggacagcttt ttcacaacct ctcaataaac ggtgttcaat cagctgaccc tgggtattag
     9781 ctcaaaacgc tggattcaca acctctttta tttcaaataa ccagtaaata caatgaacat
     9841 ctacaaaaaa cttctattta tttatagatt tcgtcaggca aatccaattc tctcttatca
     9901 atcaaagtct gataccacga agcagatttt ttcaatgttc tgcttcgttc atcgttcaat
     9961 tcgattcgaa ctaatccata tcgattctta aatgcattca ttggtgacac acagtcagtg
    10021 aatgcccata acatatagcc ttcgcaattt gcgccttctt ctgttgcttt gatcaagtaa
    10081 tgcaaatgct gtccgataaa ttcgatacgg taatcatctt gcacgattcc tttctcatcc
    10141 atatactgtt cttcatattc tcttcccata ccgttttctg ttatcagcca agggatatta
    10201 tgataatttt cttttagata catggctata tcatacatga ttttcggata gatttcccat
    10261 cccctggaat tattcatttt cttcccaggt aaatcaaaga cttcataata tcgttcagga
    10321 tggaaaggtg tctcttcatt ccattgataa cgaggggcgc gaacgcgttt aggataatat
    10381 tgattgattc caaggaaatc tactgtatga tgctgaatcg tttctaaatc ctctgttgca
    10441 ggatcgaaat aaatcgattg tttttgacac aactccagga actcttctgt gtagtatcct
    10501 tttaccatcg gatcaaaaaa tactcgatta taaaacaaat catacatata agcagctttt
    10561 tggtcttctg gagaattgga tcgagcatag accatttcag gatttaaaat acagccaatc
    10621 cttccaccat aatttccgct gcggtaaatc tctactgctt tagccgttgc taaaacttta
    10681 tgataattcc acatcatcca cttttttgtg ttttgttcat gcggccagcg aacagcatcc
    10741 aaatagcaac gcgtttgggg aacgattggt tcgttgaatg taaaccagtt ttttacccta
    10801 tcaccgtaac gatcaaaggc aatttgagca tacttagcat aaaaatcaac tacttttctt
    10861 gaagaccagc catcatattt ttccaaaaga aaagctggga cttcataatg ttccaaacaa
    10921 atcatcggtt ctacgtctgc ttcgatcaaa gagtcgatca tttcacttat atgctgagca
    10981 tattcttcat ctactataca gttctcataa tcagtaaaaa aacgagccca attgatagaa
    11041 gtccgataat gtgtcagatg gatggatttc atcagatcca catcctgctg gtattgttcc
    11101 ataaaattag ttgctacggc tgggccatac ccattatgcc aaacaaaatg ttcattttta
    11161 taccagctat ctataaacga atcctgtcct tctttttttc ctttccaacc ttccgtttgc
    11221 caagcagaag atgcagcacc aagaataaaa ttttttggaa tagtaatttt catgatttcc
    11281 tcctgttttt tagatcccat cattttccac acgatttgct acttttacaa atggcagata
    11341 gatcaaaata gaaacaataa tacaaacaag ttgcgtaata actgcaccga tatttcctgc
    11401 tgttgccaga taagcattga cgatcggcgg cattggccaa gggaccatta caactgcttt
    11461 cgccgcaaat cctaaagcgg ttgcaaaata accaatcgtt ccagtgataa gaggcgttaa
    11521 gataaacgga atagctaaaa ttggattcag catgatcggc ataccaaaaa taactggttc
    11581 attgatgttg aagatcccag gagcaaggga taacttggtg atttgtttca tatcttcccg
    11641 ttttccaact aacaatactg caatcagtaa accgatcgtg actccagacc cgcccatact
    11701 catatacata tcccaaaatg gcatagtaat aatgttcggt acttcttttc cagcttcaaa
    11761 agcttccgta tttacagcaa ttgccgctaa aagcaacggt tcccgtatcg gcttcaccat
    11821 ttgatttcca tggataccaa tcacccaaaa gacttgcgca ataaacatca atagcaaaat
    11881 acccggtaac ccttgtacga caccttctaa tgggcgttgt acgacattgt aaatgatatc
    11941 ataaaggtac attcctgtaa gttctttgat gataaatccc gcagccgcga tacccgatac
    12001 agtcagaatc gtcgggaata aagcagaaaa actagcagaa acattcgttg gcacggtatc
    12061 aggcattctc agctgtagtt tcttctgttt cctcaaccag caataaagtt caatagaaag
    12121 gatggagacc aacattccca aaaataaccc tttcgtatct gtatattgtt tagccaatac
    12181 gttttctact ataacagtct gattttcatt cactaattca taaacagttg gattaacaga
    12241 taaataagac atcactgcga tgataccagg gaatacacca tccactttat tcagcttggc
    12301 taattcgatc cctatcagaa aaacagcata gatggtcaag aaacttagtg tgacatagct
    12361 gatggcagat gcgataggct ttaattcttc taaaaaacgc aagaaactta tctgtgctaa
    12421 gccattttcc gagtcaaaga ccattgctga aaacaatgtg ccaaaagcac ccgtaataat
    12481 taccggaatc aatgcagcaa atgcgttttt tatcaccatg atatacctta aattattgat
    12541 tctcgttgcc acgttcccta aaacattggc taatttatcc ataaaactca ttccagatcc
    12601 cctcattcct gcttcttctc cttgacgtca tctctttttg tctattagtc agcgcttaca
    12661 tttcgatgaa cagaaactat ttactcctct tttttaccaa atataaaaca aaaattcatc
    12721 tgatgtattt atcataaaat acatcagatg aactgtcaat tagtttcttt ttctcctatt
    12781 attttctgta attctctccg atttattgcc atatggacag tcattgcatc aaacgcagca
    12841 agtgcattcc gcctttcgat ggcctgaacg atctctgtat gaatatcgat cgtctcgatt
    12901 ttcagatgct ggatatcata atttttatta aacaaagcaa ttgattcatt aatgattggg
    12961 ataatatgca gcaaggctac gtttccgcta gcttctgcaa tcatcgtatg aaaatcgatg
    13021 tctaattgaa catgttcttg tgtgccttct cgaaaagaag tttcaatctt ttgcgttaat
    13081 tttttcattt ggacgatttg attcttcgtt gcatattccg ctgccaaacc tgccatctta
    13141 ggctccaata aatatctcag ttcaaataag tctcgtatca tccgatcctg atcttcaatc
    13201 aaagaaaaac cgagtgggtc attggcaatc cctcgcttat cactgacaaa tgtccccgct
    13261 ccttgccgaa cttcaaggat attcctggaa gctagagccc gcacagcttc tcgcaccgtg
    13321 cttcgcccca cctctaaata atcggacaat tcatattcat tcggcagttt atctcctact
    13381 tgcaactgca tttcctttaa atatctaagg atcttgtcag tagttacttc tactagggtt
    13441 ttattttctt ccaaaccaca tacctccttt tcatctgatg tattttttcg taattattat
    13501 aacacgtttg aatcatctga tgattttttg tatacaaaat tgattaatcc gttcatagac
    13561 atacaaacga agaagatatt taccataaaa aagactagga taaaattcac tcctagcctt
    13621 cgatcatttt tattttgaac gacaaaaaat atgatgttca ataacagacg atcttcattc
    13681 gattcttgat gtcatctttt gtttttttta atatatggat aaaaagtttg attacatcgt
    13741 ttctattcta gaatttggtc gattctcaat tcttcttctg gtgagaaatc taaattatcc
    13801 atcattcgaa cactttcttg taactgactt aaccgacttg ctccgaccag tacacttgta
    13861 acagattttt gtcgcaaatt ccatgcaagg gccatttgcg ctaatgattg tcctcgtgat
    13921 acggcgattg tttgcagtgc tttgattttt tccagagttg atccaacttg ttcttctgaa
    13981 aggaatggta tttccttacg atgtgctcta gaatcttcag gaataccatg tagataacga
    14041 tttgtcagca acccttgagc aagcggactg aacgtgattg cccctagccc ttcttcttct
    14101 aatactggag atagatcgtc ttctagtagt gcacgagaaa acatattgta gcgcatctga
    14161 tgaataatga acggtgcttc ctttcttttt aaaatttcag tcattttttt tgtatcttct
    14221 ccattatagt tggatatacc aatatataat gcttttcctt gtcttacaag ttgcatcaaa
    14281 gcttctgctg tttcttccaa aggtgtatca gggtctgggc gatgatgata gaagatgtca
    14341 acataatcta gccccattct ttggagactt tggtcacaac ttgaaatgat ggatttacga
    14401 gagccccatt ccccatatgg cccttcccac atatgataac ctgctttgct agaaataatc
    14461 agttcatcac ggtaggcttg aaaatcttct ctaaaaatac gcccaaagtt tttctctgca
    14521 gctccagcag ggcctccata attattcgca aggtcgaaat gggtaattcc catgtcgaat
    14581 gcgcctctta aaatctctct ttgattatgg ataggatcat aatcaccaaa attttgccat
    14641 aatccgagag ataaaatcgg taatttcaaa cctgaatgac cggatttacg atattccatt
    14701 ttttcataac gtgcactatc tgcaatatac aatttttctc ctcctcatca aatcttttta
    14761 aaacgctttc ttttttctat ttttagttta ctacatttta aagaaaagga gttaatcaaa
    14821 atgatttttt cgtatatttt tttgccattt gttttttact cgttgataga tcagaaattg
    14881 attacgtgct tgctggattt ttttataacg tttcggttgt tttttgtaaa attgctgatg
    14941 atagttttct gctggccaaa acgtaccggc tggttcgatt tttgtgacga ttggttggtg
    15001 gaaagttcct gaactgtcta gtttctgttt tgattgttcc gctaattctt tttgtcgttc
    15061 gacttgataa aaaatcactg gacgatattg cttccctcta tcttgaaatt gtccaaatgt
    15121 atctgtggga tcagtaattt gccaatagat tgtcagcaac tcgctataac ttatttctct
    15181 tgtgtcataa atgatctcca cagcttccac atgacctgtg taaccaccac ttacttgatc
    15241 ataatttggt ttttcaacat gtccgcccgt gtatcctgac aaaacagata ggatcccttt
    15301 tttcgattca aacggctcga ccatacacca gaaacatccc cctgcaaata ctgcacgttc
    15361 ttgatagtca gcatcttgca tggcatgctt ggaaaagtca tatttttgct ccttatcaaa
    15421 tccttccgta atcaataaat aaaagtccat tacatcaggc gtcagattca ttcggatagc
    15481 taatggacgt agtgttgctt ctagttttga taactgttct ttaacggata tattttctct
    15541 tatgtcattc tttgtctgaa tcaatacttt tcgttcccaa tctcgtgtat tcggattcaa
    15601 aatcagatta taaagtgttt gaatgaatat ttgttcctca tccatagatt ctcctccttt
    15661 ccgaagaaga caagctagtg actttagctg taatttatca taaagtgagg aaataagcga
    15721 ttacttcatc cccctacaga tttttcgtat aaaaaagaga gaatccttat cgacagattc
    15781 tcctttttaa tcaatttatt ttataaatga aaagttaatt taccttttat ggaaaactat
    15841 tttaaaaaat aaacataaat atgcagttaa tgtaacaaga taagaaataa tagtcgttac
    15901 tgtataactt gtgcttactt taatatcagc aactcctttg actccgctta tttgtaccaa
    15961 tccattagca ttcacctgct cctttacagg ttgatgattt atttctacat tcgttcctaa
    16021 ataagcatat acaggaagtg tgattacttg gctcttctca ttagttactc tatatatgat
    16081 agaactacca gttgttttat aaggaaggtt tacccattga ctgccaatct ttgcttcgtg
    16141 ttttattata tgctccttat tctccaatga agcgatagga gaataatcat ataaaaaata
    16201 atccattcct ttagtggtat acgcctctac tgtttctttg tttacaacaa tatgtcccgg
    16261 ctgagaaatt attttttgat tgaaattttt tttactagaa acagttaaag tgattaataa
    16321 caaaacagtc ataaataaat aaaatagttc tcttgtctta ttgtatcttc tatttttgaa
    16381 aaatatcatc gttaatatca gagaagagaa tattatttgc aagcttaaga tccgccaagg
    16441 aaattgtaac aatttggctg gcgtattttg cagaagatac catggcacca aactagttgt
    16501 agctagccaa gtcaaacacg taccataata aatctttttt tctatgtttg ttaatttttt
    16561 aaataaaatc aggggaatac ataaagataa cagaccaact agtcccattg agtaagtagt
    16621 taagtcgttg ttcatagctt cagtcagact atcgaacaca ttagatgcat gagcatataa
    16681 atttgtcacg ctaggtttgt tgattttttg gtagagcatt tgttcaaaca tcggatacca
    16741 aaaagcactc gtcagaacca atgtcattcc tgccgcacta aataattttt taaatatagc
    16801 aataaaatct gcattcttga aacctttaga aaccaaacga ataaaaataa aaatgataat
    16861 taatgctgta ctcattaatg ttgatagtac atggctgtac actagcaaac tcatactcaa
    16921 tgctagcttt acagacggat acttttcttc ttttccagag atgatttgat aagcataaaa
    16981 taatacaggg ataacaagtg ttattgcgat agcttcggca attgcggaac gatagtagat
    17041 gtctactgtc cgataagcag agaaaatata gagacaacta aataaaaatg ccgctttttt
    17101 ttgttttaaa aaccgctcgc cataatgata agctacgagt gttgtacaca agttcaataa
    17161 ccaaacgtaa ataatatagc ttacaatcaa attttttgtc atccaatata acattacagc
    17221 tggaaaaaaa gtcagaaagg gataaaaata atttacacca tatccagtat aattgaatgt
    17281 ctcataatta atcggactgg taaaaatagt cgataacccc ttgattcgag ataagtgaaa
    17341 agaaagatct ccagtggtat aaatactctg tgtatttttg aaaaagatga aagaatatat
    17401 actactaact ataattaatc cactcaatat tactactttt ttatttattt tcattcttct
    17461 tgtttatctc ctttttagtc acatatcgag aatctttcaa cttattaggt gcaaatcgtt
    17521 taaaacttga atacaccact aaacaataag tcagaatact gatccataaa gccatgagag
    17581 cagttggagt atattttgtt gtaatttcta tcttattttc tccagcattt acatccacat
    17641 tcactaagcc atgtttttta taagagtcat ttacgacttt accgtttact tttacctgtg
    17701 tacctaaata agcatatact ggtactgtca ctttttgctt tttgttgctt gccactgtgt
    17761 aagtaatgtt attatctgca gctttatact tccctttttc ccacgattct cctactttta
    17821 cttcatgttt ttctaagtga ggcctttctt ttatcgcttc tgttggggcg taatcgtata
    17881 atcctcccat atctgatgtt gtataacgtg ggagtgtttc ttcattgata acaatatgac
    17941 cgtgttttga ttggataact tttgcgtaat tttcttttgc tgctatagac gtgacgagta
    18001 gaaacaccac agtagcgcca atgattaacc atgaatattt tttattcata gtctttttca
    18061 taaaaacaag cgttatgatc attgaagaaa aaaagatttg gatacctaag atacgccaag
    18121 gaaactggag taagcttatc ggtgtttttt gaaacaaaaa ccatggaaat aaattagtta
    18181 cgcataccca tgtagaaact acgccaacat agatgatttt ttcttttttc tccatttctt
    18241 tcagtatgaa taaaggaaaa atcaacgcaa ccaatcctaa taaccccata gtgtatgttg
    18301 taatatcgtt atttaacgct tgaatgatac tatctgaaat agaaagtgct tctagctgca
    18361 aatctgtttt gaagggactg tgtatttctt gataattcat ctgctgcaac ataggatacc
    18421 aaaaatagct agttaatgca caagtcaaaa aaacagcctt tactaaattc acgaccacaa
    18481 attttatatc gttttttatt tgcttgctta aaaacaaacg aactataatc atacaagcaa
    18541 tcaatgcact acacaatagt gtagttaaga catgagtata cacaagtaga cttatactga
    18601 cagataaagc gatgactttt ttttctctat tgaatatcaa tccataagca taatataaaa
    18661 cagctgggat aatcgtaaga gcgattgctt ctgcaattgc ggatcgataa tagatatcaa
    18721 ctgttcgata agttgcaaaa gtatataaac aactaaataa aaaagcagca tctatctttt
    18781 taaaaaactt ttctccataa taaaaactaa tcagaatcgt acaaatattt aataaccaaa
    18841 tatatagaac ataacttaat attaagttat ttgaaattcc ataaaaaacg actgcaggaa
    18901 ttattgtaag aaaaggataa aaatagttca gtccatctcc ataattgtta aatgttgtat
    18961 agttgattgg cccttcaaaa atagaagata accctttgat tcgtgaaaga tgaaaagata
    19021 aatcacctgt tgtataaatt tcttgagcat ttctcataaa atttactgaa tataaagtac
    19081 taagtaagat aagaactact aaaagaaatg cttttttact tattttcata gatttgttgt
    19141 tctccttttt taattctatt ttcagtatac tagaattgtc tttttttaat aagttttgcg
    19201 ttaaattttt catagcacta gtatgatata ctagaaaaga atcaattttt attactttta
    19261 aataggagaa aaaaatgaaa aaaaacaaaa accaaataat agatatcatt tttatgttat
    19321 ttctaagttt tgcttacgtc atccctctat tcatgtctaa gggaatctat catagtgtca
    19381 atcaggatac ttactttcat ttatctcgaa tcataggact agataatgta tggagttctc
    19441 cagtaaactt caataacttc gatcatcatg gaacaatgat gaatattttt tatccatggc
    19501 ttactcttta tccagctttt ttattttata aaatgatggg aaatcttgtt ttaagttata
    19561 atatctacta tttttttatc acttttttaa caatggtcgt ttcttatttt tctatgaaac
    19621 aaataaaaaa caatcgttat atttcgctgt tattttcgat tatttataca ttttccgcct
    19681 atcgtgccat tgacatattc catcgtgctt cattgggaga agctgtcgct ttaacatttt
    19741 tgcctttgat actaatgggg tgttacgaaa tttatattag agattaccaa aaatggtact
    19801 ggttgtctat tggcatgacg ctagtagtgt atactcattt actttctgtc gctatggttt
    19861 ctgtatttat tggaggaacg ttgtttcttt ctttttattt ttgggaccaa aaaatcgcta
    19921 gactcttaag tcttttaaaa gctaccgtcc tcaccttttt tttaagtgcg ggattcttaa
    19981 ttccttttat tcaacaatct agagcacaag aattgaaagt cccactggga aaagaattaa
    20041 gtggtatggc tcctagtgat atgctgacac atattttaaa taataactat aacaactata
    20101 ctattggatt attcttattt ctcggattga ttggtgcttt tatttttata aaaaaattaa
    20161 ctgctgatga tttatttatt ttctttcttg gtgtatttgt tcttttttgt tcaaccaatt
    20221 tatttccttg gcaacttttt aaccatacac cagttaagag tctacaattt gtctggcggt
    20281 taaatggttt ttcttcttta tttatagcct atacgatgag tatagtgatc tattatattt
    20341 tttctactaa aaataattca tggaaaataa tggtctttac gtttcttgca ctaatattgc
    20401 atctctcagg agtaagcaat tctatccatg ctaacaaaga ttcattaaca cttatagcac
    20461 ctgaagacgc tgttgctata gctgaaaatt acaatcatac tgattatgca aacaaagagt
    20521 caatctatca tcctgatatg attaataatg atcaatattt actaggtaac caggaaataa
    20581 atccaacaac tcattttatg agtaacaaac ttacaattga attagataat tcgaataata
    20641 aaaatactgt cttgacgaca cctatttatc gttataaagg gcaagtggct tctattaatg
    20701 gcaaactagt acaaacaaaa ttatctaagt ttggcacaac tgaattaact attcctccag
    20761 gtataaataa agtcgttatt acttatcagt acacaaaact agcaattgct tcaagatatt
    20821 tatctatcgt tactttgatt ttatttttac tttatcgatt tactttttct aaacaaaaac
    20881 aaccgagaag agaagtacaa cattctcact agatttttat ttaagaaaga ctttttagct
    20941 gtacacataa acaggctaaa aagtcttttt ttatatttct ttaatttgct tcatacatta
    21001 tttaacatcg atatttatac tgtgaaacat gcgtttcatc cattatcaaa gtatttttat
    21061 cgataataaa cttcatccaa aaacagacct tgtgcaggga cggtttctcc tgcatgttgc
    21121 cgcactttgc tttcaaatat ttcatcgatt gtttctatcg gcatggcacc tgtgccgatt
    21181 tctagtaatg tccccatgat aatccgcacc attttatata agaatccgtc tccgacaaaa
    21241 gtaaaatgaa gcatttctcc ctttcgttcg atagataatt catcaatcgt acgcactgtg
    21301 gatttttttg attttttcaa tgcagaaaaa ccaatgaaat catgtgtacc cactaatttt
    21361 tcgcaagctg cattcagctt gtccatatcc aactcttgag ggaaataaaa gctgtggttt
    21421 cgctcaaatg ctgaaggaat cacgttgttc caaacataat agctgtattt tttgcccacc
    21481 gcattatatc ttgaatggaa gcgctcaggc atttcttcga ttcttttgat gacaatatcc
    21541 cgcggaaggt aacgattcat aaagtcgatc atttctgcca gtccaatttc tgtgtttgtt
    21601 ttaaaatttg ctacttgtcc tcgcgcatgg gtgccagcat ctgttcttcc tgatccaata
    21661 atttctatct cttcatttgt catctgatgc aatacttttt cgatttttcc ttgaatggtt
    21721 ttatcgtcat ctccaagtct ttgccatcct gaatatcttt ttccgtcata ttcgattgtc
    21781 aacttgatgt ttctcatatt ttagtggctc ctctgtcttc catttggtct tctctctacc
    21841 tttttaagat tgtagcacaa aatatagctc cttgcttctc taagacagaa gctatacaag
    21901 aaaactgtgg aaatatatat ttcagaaaaa caaaaaacag ccaccggatg aagtatccgc
    21961 tgactgttca atttgacggc tcaagtttta ctgtttgaga tgcaagatac tcaaccaggc
    22021 aatgggcaca taattaaaga aaaaactgat tctttggcaa aaacctattt tattcagtaa
    22081 tggccaagaa tttatagaag gaattcttgc cagtccataa atcgccgcaa aaagcaaact
    22141 gatcacagac agtccaaggt ataagtggct tacgtccatt tgcccatttt ttcgatagat
    22201 caagaaaaga agaactggaa acaataaaaa accactgtaa cctaaacctg atccgatatt
    22261 atggacccat gtcgagacat tccacgaaga ttcatgggta ttgatactga acaaacctgt
    22321 aaagatacaa tcacctatac catagaacgc gatggctgct gtaactaggg tagctaacac
    22381 acgagatgta ctaacaaatg cagcatacaa tgcaggcaat gacaggatga aaaagatccc
    22441 tgaaaccaca gaccaaataa gaaacgcttt tcttacagga ctggaaacct ctccaaatac
    22501 actgatcacg ctcttcattt gatctaattc aggataatac aatcctaata cgtacggagt
    22561 caaaaaatca ctcagcacgc ctaataataa aaagaaaaaa ccaaatttac gtaaaaaatc
    22621 catgatacgc ctccaataac aattacctat gcttttaatt gttattataa acgactttat
    22681 cttgatttaa cagaaacctc tatttacacg aacatctata taactcatta aaaactcgaa
    22741 tcattttaaa aatactaaat atctaacgtt caacgttcac ttaatccatc taaacaatct
    22801 ttcaatttga ttttttcccc acttctttta cgcgcgccta gctctcctat tgcagtaaac
    22861 aacagatcac ttgacgaatt taaggcagtt tccattgaat cctggataac accgataata
    22921 aatccaatac cgacgatttg catcgcgaca tcattagaga taccaaacaa actacatgct
    22981 aatggaatca ataacagtga accgcccgca acacctgaag ctccacaagc agctaaagca
    23041 gacaaaatac ataaaaggac tttcaaaaca aaaggtgctt caatccctaa agaatgtaca
    23101 gcagtcaacg tcatcaagga aatggtaatc gcggcaccgc ccatattgat cgtagcacct
    23161 aacgggatcg atatggaata agactctttt gtcaatttca atctttcagc caacatcatg
    23221 tttatcggga tatttgcggc agaacttcgg gtaaagaaag cgggaagtgc gctttctttc
    23281 aaacaaaaga aaatcaatgg atagggattt tctttaataa acaaaaacgt gaggaatggg
    23341 tacacaacta atgcgacaaa cagcatcgta ccgatcaaaa caagtaaaag ctgcagatac
    23401 tctgccaatc cagcgattcc agtcgtagca attgattgat aaaccaatcc taaaatccct
    23461 atcggagcaa atgcaataat cacttgtacg acttgtgaca acgctataga tatctgatcc
    23521 accaactctt ttgtcgattc tgaacgtgct cgaaaagcta gtcccaacaa tacagcccag
    23581 aataagacgc caaggtaatt cgcatcaata agagattgaa caggattttg tgtgacattc
    23641 gtcaacatag tagataaaac actttccaaa ctttgcggtg ctttttcaga tactgtttct
    23701 tgtaaagtaa taggaacagt aaaaattgaa cttacaataa ctgctacaag tgcagaaagc
    23761 aatgttccca ctaaatataa gatcaaaata ggcttcacga atgtcttatt cccaatttta
    23821 tgcttggcaa ttgacgccat cgtcaagaaa aaaaccagaa taggtgcgat tgccttcaag
    23881 caactgacaa acaacgttcc caatattgaa ataaatgtcc atgtggggaa aaagatacca
    23941 aacaatattc cgactaaaat accaacaaca atacgttgaa ctaacgacat atccaaaaac
    24001 ttctctaaca aatgaccacc ctttcacaat tttaacaatc attgtatcat tttatgcaaa
    24061 gaaactaaag gtataatttt ctaaaaattc taacaataca aacaaccatt tcttgctaat
    24121 tttgtacttt ttctgtctac acgttgtttt ttgagatatt ctaagttagg atgttattaa
    24181 tgggcaactt atcaggaaac gttttcttat gtttttgtcc aatttttttg tgaggtgttt
    24241 attcttgaaa aaaataaaga aggagagtta tggcttcctg acaatctttg tcgcttgtat
    24301 aatgatggtt ttacagcgta tattgatttc agcagtcact attcctacat atgcaacaaa
    24361 ccctggtcga ttctacatct atacattttt acaaacttcc gttgttattg gtgcaaattt
    24421 gatcccactt tacatgggtt accaatatca aaaaatcgcc cgtttaaaag ttttacatta
    24481 tttaagtcgt tttgccttta tattcctaat agccacacta gtttgcaata tcttttttta
    24541 cgtacaagct ggcagcttga atattcgtga ttattggctt atcctaacac ctatcagtca
    24601 gaattacttt acttatgctg tttcttgtac tttgcttttt tgtagtattc cttatacagt
    24661 tggattttta aataaattat cgaaaacaac aattaaatat ctactattat ttttaacaat
    24721 tggattagtt ggctgctcta ctctatttaa taaagacccg tttgcattac agaatggaca
    24781 gagtatttta tggatttttt atttattttt aatgggttat ggtttgaaag aatggaactg
    24841 gaaagaaaag gtccgctata agcttcctca agtatttatc agcttgattg ttttattcgg
    24901 tttgattatt ttgatgacac aaatttcact catcatcaga ggaaatacag atacagcgct
    24961 gaggttttct aaaccatatt ctctcttcgc aatgtattat actttctctt cgtttttatt
    25021 tttagaaatg ctatctgata aattaggtat aaaaggaaga ggaaattttc ttgctgtatt
    25081 tttgattgtc actcaagtta tatgtaattt ccctttagtt tcttatcgcg tatctacatt
    25141 tatgaaacgt gaatttccaa actcagggaa ggcatggctg ataaatatcg ggcagttttt
    25201 tatttgatat ttattagcag tgtccctcct agttatcttt ttattttata tacaaaaaat
    25261 ccgtttcatt catcgtttca tcgaatactt cgcttttgat tcgattgaac aattaactca
    25321 gcgttggaaa aaaagaattc attggctttt tgttcataaa agttattttt tagttgcagc
    25381 atttttttac tgctttacct tcgtgcagat tttcgtttta gaaccaaaag aaggttggaa
    25441 agaaactatc caggttgcct taaaaatatt tactcagcga caagcaccca tgatcctgac
    25501 aatcatcatt attatgggat ttttcttctt actattgttg atttccaatc gtttttggta
    25561 cgccttgact gctaccttga tcattaactt actgctcact atttcgacag taatcaaaat
    25621 ggaaatgcgg gaagagcctg tctttccttc agatttaaaa atgctgaccg gattgtcaga
    25681 actattatcg atggttagcc cagtcttatt aatcgtgggc ggattgatcc ttctcctatt
    25741 attgattact agtattattg tacaacgtag actacaaaaa cagtattcct tgaagattca
    25801 ttggaaacgt cgatttatca gtatcgctgt attattagga tgtttttcgg gtgtcttttt
    25861 cattaatcac aaaaattcgc cttctttctt gctgtttaat ttatttaaag taaacaagac
    25921 tttctttaac cagcaaggcg ccgtaaaaga taacggacca gtcattcaat tcctaaacaa
    25981 tatcgacatt aaaatcatgg aagaacctgc tggctattcg aaagaaaaaa ttaatggaat
    26041 aatgaaaaag tacaacacaa aggcagatga aatcaaccaa acaagaagtg actggttaaa
    26101 caatcagacg atcgttctca atttaagtga aagcttcagt gatcctgcac gtgtccctaa
    26161 tctgacagta cctacagacc ctattcctta catcaaaagc attataacag aaggaacagg
    26221 aggattgatg ttatccgtcg gttatggtgg cggaacagct aacatggaat gggaaggact
    26281 gacaggcttg agtatcagta acctgtctgc ttcgttagtt acaccttata cccagctagt
    26341 ggagcgtcag aaaataagtc caaatattac cgatctattc gatgaaaaaa tagccatcca
    26401 tccttttaca gctgctcttt atcgcagaaa acaagtgttt gataaatttg gttttgacag
    26461 gttctattat ttagacagtc cggataaatt aacttatacg gataaaatag aacaaagccc
    26521 acgcatatcg gatgattcag catacaaaga aaccttgaaa gctttacaaa gcaatacgga
    26581 aacgtcacaa ttcatccaat tatccactat gcaaaaccat atgccttatg atgattacta
    26641 tagtgaattg aactacactg ctgaaggaac tgctgtcatt cctaatagaa gaaaagaatt
    26701 acaaacttat atgcaaggcc ttcactatac cgatacagca gtaaaaaaat tcatccaaga
    26761 aatcgacaaa atcgataaac cgattacctt tgttttttat ggtgaccatt tacccgcaat
    26821 ctatagtggg aatgattcga aaaaatatgg attagaacag caccagacag attatttcat
    26881 ttataacaac aagtatagtc gtgaacaagc agctacgtta aataaagaag ttgttgctcc
    26941 taataacttt ggtgctatgg ctcttgagca tgcgaatatc aaagtaactc cttactatgc
    27001 gttgttgaca gaagtatcta atcatctacc tgcattaaca attgatccta cagaaagctt
    27061 gtctaatcgt tttaatggaa aacaggtctt tgttacagag gatagtcaaa ttatccaaga
    27121 aaaaaattta actgagaaac aaaaagaaat tctagaagat tatcgtctga tacaatatga
    27181 tcttgttgca ggtaaccagt acagtgcaac atgggcgaca caaaaaataa aagactaaca
    27241 aataaactga gcaaggggtt gtgataaaag acatgtcaca accccttgtt tatctcatta
    27301 atttgcttgt ccataaacga tttgattaaa gccatttttc aattcattat tcgctgtctc
    27361 gttgaagtaa agataattat cgggattccc ctgattttgt tgtgtcacca atacttttgg
    27421 ctgattttgc tgaaacccga atagatagac gtgctttttc agatatggtt ctgtctctgc
    27481 atcggaatag acggctgtga tttgatagtc tgcttgacct gtcccacttt ctgaccattc
    27541 tgcagaaaca ggcactccac caatagccat cttccactcc ccgttcaaaa tagcttgagg
    27601 gactttaaga ccatataagt ccacactcat ttgattcgta taacttttgt attgttgtcc
    27661 cattgtttgg ccccatttgg tcataaatgc ctctaattgt gcggatttgt ctgcattcca
    27721 cagtgtttgt tcaacttgtt cgctgctttc tgaagaggaa gatgaagcct ctacagaaga
    27781 acttgaagta gatgtttgag ttgtttcagt cgttttggaa gactctgacg aagtagaggt
    27841 atctgctgtt tctgtacttg ctgcagttga cttgctctct gtgctagttg ttgtagtagt
    27901 tgcaactgtt gctttcgctg tttcttttgt tgattctttt ttcgattcat tcccgttggt
    27961 acaaccagct aacaaaaaag ctagaccaat tgttactaaa atcctttttt tcaattaaaa
    28021 aactcctttc gattactccc acttctttat tctatcaaat aagcaatgtg attttattga
    28081 tttttcgtat tttctcatca atctttcaaa tcttctaaaa actgagaagc acccgctgat
    28141 gttgtctgta atacatcagc gggtgcttct tttattttaa tcttcgtgat tttccaattt
    28201 acctcacgct ttatatttgt atttgaagaa acatagactt ttagtcatca tcgtcttcct
    28261 catccaaatc ttgtcggaca gtttttcctt ggagtctttg tacttggtag atgatttctt
    28321 tattgaaact taaaagttca acaagcaatt gttgcaagcc atatttttct tctttttcag
    28381 ctaatttgat tgcccgtgtg ataaagacat tttggaaatc aaaatctttt gcaaagtttt
    28441 ccaacattgt tgaggctggt aaatatttgt tttgaccatg ttcgtaaatt tttccataac
    28501 gcatgacttc ttctaaagta gacggaacga tttcattttc aatcactaac tcatgagaga
    28561 ttttattgaa ccatctcgct tcttgatcag catattctga aaaaagggta cttaattctt
    28621 gcgaagatgt acccaaaaca tacaattgtg cttggatcaa tttcatttct tctaatttaa
    28681 aatttgctaa tacatgcccc accatggcgc cagcagttgg tttatgatgg tcgatatctg
    28741 cttgttttgt ttcttgaaca aatttttctt ccactatatt cattgattta cgcctctttt
    28801 acttttgctg attggacttc ataacctaat ttttccacaa ctgcagctaa ttgttcaggg
    28861 tggacttcat ctggatcaaa gtttgctttg attttgctcg cattaaacaa aactttcgta
    28921 ttgcttaccc caggctgttg agaaaccgca tgttcgattt tttgcataca gcttggacaa
    28981 gctagtgtat ctaattgcat aataattttt ttcatcgtag ttcttccttc ctttttcttg
    29041 atagtcttat tctagattac agcttccata aaaaaattga ttcttatcaa gttttacgat
    29101 ttttcttctt tgctttcgtg tccaaaatac aataaacgca tcgcgttaaa gataacgatc
    29161 aagatactag cttcgtgaac gaacatccca ctagccatgt aaataaaccc ggcaaataag
    29221 ccgttgagta aaaataagac gacaccaatg gcaatcacta cattttcacg ggtatttaaa
    29281 acagttttct tagccaagcg gtaggcatga accaacgatt caaaattaga ttgcatcaag
    29341 acaacgtcac tcgtttcgat agcaacatcc gttcctgatc ccatagcaat cccgatatca
    29401 gccgcagcca aagagggaga atcattgatt ccatctccaa taaaagcaac gcgcaatcct
    29461 tgttcttggt attttttcac aaattgaacc ttttcgtctg gtaataattc agcatggact
    29521 tcatcaatgc ctaacatatc agctacataa tcagcagtca tctgattatc acctgtcagc
    29581 atcactaact gttttgctcc tgcttgtttc aacttagcta attgttcagc gacttctggt
    29641 cgaatcacat ctgacacacc tatgatttga gtgatttttt tgtcgattgc tacaataatg
    29701 accgagctgc ctgtttgttg taattgatgt aaatcttgta cttgctttgg tgtgagagaa
    29761 agtttgtgag cggcaatcaa tttggtgttg cccgcacaaa ctgtatgacc atcaatctca
    29821 gctgtgattc cttgtccctt gattgtctga ttatctttga ctgctaattg ttgaaaatca
    29881 atgtctttct cctgagcata atggatcacg gcgcgcccca gaggatgatc ggataacgtt
    29941 tctaatcgag ccactaaagc taagctgtcc ccttcatcct ctgtatagtt cttgatagtg
    30001 gatacagcag tagttccttt ggtcaatgta ccagttttat caaagacaaa agtatcgatt
    30061 ttggaaaaag tatccattgc ttcaccgcct ttgactaaga tgccccgttt cgctccatta
    30121 ccgattcctg ctacattcga aacaggcgca ccaatgacta aagcgccagg acaaccaaga
    30181 accaaaacag tgattgctaa acgaaaatca cgactaatca gaccaacaac caacgcaata
    30241 agtaaaacgg ttggagtata atactgagaa aatcgatcaa tgaatttttc cgcatgggat
    30301 ttggtatctt gtgcttcttc tactaattcg ataattttgg caaaggtcgt atcatctccg
    30361 accttagttg cttcaatcgt cacgtagcca tctgctaaaa tcgttccaga gaagacttca
    30421 tctccactga ttttgacgac ttgtcgtgat tcaccagtca ctgcggcttc atccgcatac
    30481 cctttcccgt caatgactcg tccgtccaca ggaatagctc caccagtttt tactaagacg
    30541 atatcgcctt cttccacgtc atcgatttcc acttcttcag tcgttccatc ttcttggaca
    30601 acactagcag tagatggggc catctcggtc aaagccttga ttgactcccg cgttttggtc
    30661 aatgtttttt gttccagata gctaccaaac aaaaacaaga atgtaacgat agctgactcc
    30721 ttgtattctc cgatcataaa ggcaccaagc acagcaatag taacgagtaa atcaattgag
    30781 ataactttga ctttcactgc ctgatacgca tggatcataa taggtatgac cgcaataata
    30841 gaagctatgg ctagagcaat gttatagaac aagacaaaac cagtaaattt tccgataaaa
    30901 ccaaaaataa tcaacacagc tgataaggcg gtgatatgat ttcgatgctc ttggatccac
    30961 ttttgtaatt tcatctttct ccctcttttc ctttcattct tacgagacta agtatagata
    31021 cttatccatc ataaaaaatt gaccactatc aagtttagtc aaaaaggcgg ttttcttttg
    31081 gtagaataca ctacaaaaaa tagttagcaa gaagactcac taaaagtgat cttgccaact
    31141 attgtcgttt ctatcgaaat tttcattgaa tgattttcct gtacagcata catcggagat
    31201 ctatttcttt atctaagatt tttatcttgc taattttttc ctttagtctt tcaaatccac
    31261 gtcgttcata gaattgatac gtacagccac tatctgtaaa aaggaatatt tcttttcctt
    31321 tctctctttt ttcaaattct gttagcaact tggtaccgat gccttttgtt ttcaaatcag
    31381 gatttgcagc taaaaaaatg atctctccat ctggcgaatg cttctttaaa tatgctgcaa
    31441 gcatttgttc atttgctgtc tcgtaagctc ctttactttc tttagcaaat atattttgta
    31501 aaaaatcgaa tatcttaaca tatatttgct gtccaaaaga acgatgtttc tttttttctc
    31561 cttttatctc cgccagcaaa acacctgcca actcgtcctc tgcatacaaa gcaagaattt
    31621 gagttgctcg attcaactcc atatacaaaa aatatcttcc gtaaagattc agcagaagtt
    31681 cattttccat atatctctca aagttcattc cttcaacagc aaaatagata gcttttttgt
    31741 aatctttctt ttctaagggt ttaaaagtta gtttcatcat ttcgcctcct caacttcaat
    31801 gattgtgtta tacttacatt ataatagaca cagtgtctac tatctataat caatcatcta
    31861 taagtttgtc gattaagcga cagctttgct ttgatatgtc ggataaggag ataggtaaat
    31921 gaaaaagaca gatagacgcg tcaaaaaaac agaaaaagct ttggctgaaa cactatccac
    31981 attattagta aataaaaaga ttcaagcaat cactatacgc gaactaacag aaacggcaga
    32041 tgtacatcgt tcgacttttt atacacatta taaggatatc tatgatctat atgatcaatt
    32101 agaaagcaac ttttttcggg atctaaatga aattctctct tatgatccag cccatagcta
    32161 tgaggaacta tacactcgct tgattgacta tgtttacgca aatacttttt tatatcgctt
    32221 atttatcctc aaccatggtg atatttcgtt tcagaagaaa gttaaacaag ttattgaaga
    32281 aaactatctg aacatatggc tatatgaaga caagaaaacg attatcacag aagaaatgag
    32341 attctttact acgtaccacg tccaaggttg tctatccgtt ctcaatcggt gggtagaaag
    32401 caattacaag tactccaaaa aagaattatt agaactctta cagaaactga atgatcacat
    32461 agagaaaatc atgccttgaa taaaaacata ctaagcttag ttaagaagaa ccgtaacctt
    32521 ctcgtataac aactgaatct tatttagcca aattgtttac tgaagatttt ttgagtaaaa
    32581 tttctataat tcctacttat tgaaaagtag tttgtagtgc tgcttctccc tctctaagtg
    32641 atatatcttg ttgtaccaat caaattcacc tcatcattaa taaattactt ttaggctaat
    32701 ttattacaac ttataggttg aagctgtaac caatttatag tcatattata tttttatcat
    32761 ccagtttatt gaattcttct cgtttacctc aattcatttt caaggggaat cagctcatca
    32821 tctaacattt tacgccatgc tcgcttcatt tcttgtgggt atttaaatgg tttcgcttct
    32881 ggatgtttgg ctttatatcc ttcgtaatcc ttactgttga taattgcttt catattagga
    32941 attggatctt cacctggcat atattgcaga ttagaagcat gtaatttttt ctcagaaaca
    33001 aaccactcat tggaaaagac atgaatcaaa tcatcactta cttgtgtaaa atagcgacgt
    33061 ttaatgacaa agatatcttc attgctatct agtgtacctt catttctttg tgcttaaatt
    33121 caaagataat tttctcaata aagatttttg attccagtaa gattccttta ctccttttac
    33181 aacatagcgt tgtcctttgt tttgaaacat cttcttcccc tctttgccat taaaaatagc
    33241 ccaattctct ataaagaaga ttaagcttca ttattataat ataaagttta aatttggttt
    33301 attac
//
LOCUS       DAFLWZ010000026        31288 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000026 DAFLWZ010000000
VERSION     DAFLWZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.026"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            147..1016
                     /locus_tag="L1V38_001275"
     CDS             147..1016
                     /locus_tag="L1V38_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBN1315834.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="L1V38_001276"
     CDS             1225..2250
                     /locus_tag="L1V38_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1315835.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="L1V38_001277"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="L1V38_001277"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBN1315836.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="L1V38_001278"
     CDS             3333..5036
                     /locus_tag="L1V38_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1315837.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="L1V38_001279"
     CDS             5038..7071
                     /locus_tag="L1V38_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1315838.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="L1V38_001280"
     CDS             7082..7522
                     /locus_tag="L1V38_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1315839.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="L1V38_001281"
     CDS             complement(7722..8849)
                     /locus_tag="L1V38_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315840.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="L1V38_001282"
     CDS             complement(8852..9529)
                     /locus_tag="L1V38_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315841.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="L1V38_001283"
     CDS             9793..11559
                     /locus_tag="L1V38_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBN1315842.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="L1V38_001284"
     CDS             11574..12011
                     /locus_tag="L1V38_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1315843.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="L1V38_001285"
     CDS             12024..13175
                     /locus_tag="L1V38_001285"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBN1315844.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="L1V38_001286"
     CDS             complement(13237..13935)
                     /locus_tag="L1V38_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBN1315845.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="L1V38_001287"
     CDS             complement(13928..15280)
                     /locus_tag="L1V38_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBN1315846.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="L1V38_001288"
     CDS             complement(15503..16903)
                     /locus_tag="L1V38_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBN1315847.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="L1V38_001289"
     CDS             17064..17801
                     /locus_tag="L1V38_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBN1315848.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="L1V38_001290"
     CDS             17926..18405
                     /locus_tag="L1V38_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBN1315849.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="L1V38_001291"
     CDS             18402..19169
                     /locus_tag="L1V38_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315850.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="L1V38_001292"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="L1V38_001292"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1315851.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="L1V38_001293"
     CDS             complement(20072..20674)
                     /locus_tag="L1V38_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1315852.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="L1V38_001294"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="L1V38_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="L1V38_001295"
     CDS             21355..21939
                     /locus_tag="L1V38_001295"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1315853.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="L1V38_001296"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="L1V38_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBN1315854.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="L1V38_001297"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="L1V38_001297"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBN1315855.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="L1V38_001298"
     CDS             23840..24019
                     /locus_tag="L1V38_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315856.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="L1V38_001299"
     CDS             24041..25066
                     /locus_tag="L1V38_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBN1315857.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25257..26501
                     /locus_tag="L1V38_001300"
     CDS             25257..26501
                     /locus_tag="L1V38_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBN1315858.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26654..27601
                     /locus_tag="L1V38_001301"
     CDS             26654..27601
                     /locus_tag="L1V38_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1315859.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27735..28364
                     /gene="upp"
                     /locus_tag="L1V38_001302"
     CDS             27735..28364
                     /gene="upp"
                     /locus_tag="L1V38_001302"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBN1315860.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28503..28745)
                     /locus_tag="L1V38_001303"
     CDS             complement(28503..28745)
                     /locus_tag="L1V38_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315861.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28866..28938
                     /locus_tag="L1V38_001304"
     tRNA            28866..28938
                     /locus_tag="L1V38_001304"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28899..28901,aa:Thr,seq:cgt)
     gene            complement(29057..29695)
                     /locus_tag="L1V38_001305"
     CDS             complement(29057..29695)
                     /locus_tag="L1V38_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1315862.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29818..30450)
                     /locus_tag="L1V38_001306"
     CDS             complement(29818..30450)
                     /locus_tag="L1V38_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1315863.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30801..31100
                     /locus_tag="L1V38_001307"
     CDS             30801..31100
                     /locus_tag="L1V38_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1315864.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10686 a         5455 c         6295 g         8852 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatcca gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaattgt aggaaaataa aaaggagctg ttgtttgtgg
    25261 tagattacaa aacgtttgac cctgatcttt gggctgcgat cgccaaagaa gaagaaagac
    25321 aagaacataa tttggagctg attgcctctg aaaactttgt ctccgaagca gtgatggctg
    25381 cacaaggaag tatcttgaca aataaatacg cagaaggtta tccagggcat cgctattatg
    25441 gtgggtgtga atttgtcgat atcgttgaaa atttagcgat tgaccgtgca aaagaattat
    25501 tcggagcgaa atttgcgaac gtccagcctc actccggctc tcaagccaac acggctgctt
    25561 atctcgcttt ggtagaacca ggggacacga tcttaggaat ggatctttcc gcaggcggac
    25621 atctaacaca tggatcacca gtcaacttca gtggcaaaac ctatcacttt gttgcttacg
    25681 gtgttgatcc gacaacagaa gttattgatt ataatgtggt acgtatttta gctagaaaac
    25741 atcaaccaaa attgatcgta gcaggtgcca gtgcttacgg acgaacgatc gactttgcga
    25801 aattcagaga aatcgcagat gaagtaggcg caaaactgat ggtagatatg gcacatatcg
    25861 caggattagt agcagcagga cttcatccta atccagttcc ttatgcagat atcacaacga
    25921 ctaccactca taaaacattg cgtggccctc gaggcggcat gattttgaca aacgatgaag
    25981 cattagcaaa aaaaataaat agtgcggtat ttcctggtat tcaaggcggc cctctagagc
    26041 atgtgattgc gggtaaagca gtagcattca aagaagcatt agatcctgca tttaaagaat
    26101 atagtgaaca aatcatcgcc aatgcaaaag caatggtcaa agttttcaat caagcaattg
    26161 gaaccagagt catttcaggg gcgacagata atcatctgat gttgatcgat gttcgcgagt
    26221 taggtataaa tggaaaagaa gcagagagca ttttggacag tgtgaatatc actgtaaata
    26281 aaaactcgat tccttttgaa acactaagtc cattcaaaac aagcggtatt cgaatcggca
    26341 cgccagcaat cactactcgc gggttcaaag aagaagatgc tgtaaaagtg gctgaactag
    26401 ttgtcaaagc attacaagca aaagatgata acgctcaact agacgaagtc aaaacaggtg
    26461 tacgcgaatt aactgaaaaa tttccgttgc ataaaaaata aaaatttaaa ttccattagt
    26521 aaacagaaaa gttcaatgtt gggcttttct gtttattttt tgggaaaacg gattctttga
    26581 caatatcggt gatgctctct agtatatgag gtgtaatttt agtcttcaca ctaaatctca
    26641 gggaggaaaa gtcatgactg atcgtatctc gttagaaaag gaagcagtag cattcagtga
    26701 tgcaaatgcg cctcatccgc gtatctatga actagcaccg gaagaaggaa gagttttact
    26761 agaagaagta caagaatcac ctgtgaacaa atattccgtc gatattgaag acttgatggt
    26821 ggatactggc gaatggggaa aactcaatat tcgtctcgta cgaccagaag ggaatatgga
    26881 taaattacca gttatttttt atattcatgg agcaggctgg gtttttggca gtgctcaaac
    26941 ccatgataaa ttgatcagag aacttgcggt tcgtacgaat tccgtcgttg tctttccaga
    27001 atatagtcga tcaccagaag caaaatatcc aacagcaatt gaacaaaatt atgctgtgtt
    27061 gcaacagctg aataaattag ccaagtcaaa aaatctggat ctcgagaatc taatcgttgc
    27121 aggagattca gtaggtggta acatggctac agtcatgacg atcttaacaa aagaacgaaa
    27181 gggcctccca atatccaagc aattgctgta ttatccagtc acaaacgctg attttgatac
    27241 agattcctat catgaattcg gagaaaacta ttttttgaca agagaaggaa tgatgtggtt
    27301 ttgggaccaa tatacgacga atgaagaaga gcgtgctgaa atcacagctt cgcctttgag
    27361 agcaaatata aatgaactaa atgatcttcc ttcagcaatg attttaacgg gagaagcgga
    27421 tgtattaaga gatgaaggtg aggcttatgc gcgcaaactt cgtgatgcag gggttcctgt
    27481 tacacaagta cgcttccaag gaatcatcca tgattttgtc atggtaaatg ctatggatca
    27541 gacaaaggca acgcgtgcag caatggcatt atctacttct tggatcaaga aaaaagaata
    27601 agctttgctt gtccgcagga aaacttcttt tcaaaaacgg attttcttag gaaaaatggc
    27661 gagtttgact agtcaatcac ttgattttgt tttacaatta aaaagaaacg acagaacaaa
    27721 ggagagctta aaaaatgggc aaatttcaag tgatcgatca tccattgatt caacacaaac
    27781 taactattat tcgggacaaa aactgcggaa caaaggtttt tcgtgaagta gtcgatgaaa
    27841 tcgctatgtt gatggcatat gaagtatcac gggatatgcc attggaagac atcgtgatcg
    27901 aaacaccgat cactgaaaca acacaaaaaa cgttgtctgg taaaaaagta gcgattattc
    27961 caatcttgcg cgcaggtatt ggaatggttg acggtatctt ggaattgatt ccagctgcta
    28021 aagtgggaca tatcggtctt tatcgagatg aagaaacatt ggaaccacat gaatatttcg
    28081 tcaaacttcc agaagacatt gatgcacgtc agttgtttgt agtagatcca atgttggcaa
    28141 caggcggatc agcaatcatg gcaatcgatg cattgaaaga acgtggcgcg tcgaacatta
    28201 aatttgtttg tttggtagca gcacctgagg gagtaaaagc tttgcaagaa gcgcatcctg
    28261 atattgacat ctatacagct tctctagatg aaaaattgaa tgaacatggt tatatcgttc
    28321 ctggactagg ggatgcgggt gaccgtttgt ttggtacaaa ataagtaaat acgaaaaagg
    28381 gtgtgacaca acttttgtca catccttttt tggtcatttt taacgtttga tgcagaacag
    28441 ctttttcaca gctttcgttt gcatataaaa aaaccatccc aaaaatgcag agatggtcaa
    28501 attcaaatct tttttagttc tttgtagtta acgattacta cacccttact ttgcgtcatc
    28561 aagttcgcat tttctgcagt ttcatcaatc tcaacaacag cggaattttt caattgcttt
    28621 gaaatcgttc cagtttgcga cttgccgtga attgtgaaca ttacgtgagt attgatcttg
    28681 aatttttcac caatttccga tggtacgata gttgtatcaa attttccaaa agttgccatt
    28741 ttcataaaac ctgcctttca catcaattat accacgtttt atgaaaaata tcatgaaatt
    28801 aaactaattt tccatcggac tctttacaat cagccaaata gagtatataa tttcttttgg
    28861 ataaggccag cttagctcag ttggtagagc aacgcactcg taacgcgtag gtcgtaggtt
    28921 cgatccctat agctggcatt aaaagagaag acagatatat caaggatttt taatccattg
    28981 atacatctgt ctttttgttt aaaggaaata aagtatgctt tcttagcaat agagcatgta
    29041 ttatttctat aaaaatttag gagaataaaa cgactagcaa tatagctgtg aaatcaaata
    29101 tcacatgaac tgcccaactt gtaatgatcg agttgctttt aatggcagct tggttgaata
    29161 acaatcttgc caccccttgt atcaaaagga tgtgtgctac agtgtgtaaa atatttccat
    29221 tatcataagt actgtaatgg ataaatccaa agatgattgc tgacaagaaa ctagcgacag
    29281 gaatgctgaa cttactagaa aaaatagcga gaaaatacac tgagaacaat tcttctccaa
    29341 gtatcatgat aggcaaaata ataaataata acgggctgaa agcctcattt attggattgc
    29401 ctgttaaacc ccatttcaaa atttgttgca aaaataccga gactgcggca ctgattacta
    29461 cattgataaa aaaatatttg gctatatttt tgacaggagc gacaggtttc gagaacattt
    29521 ttttcgtatc ttttttacca aaaacaagtg taaatgctat aaatccagtg atagttaaag
    29581 aaaaaatgct aataatggat ggcgcaaata gcaaccctaa caaaccgagt acaacgacaa
    29641 tagtgcccaa tatccctttt ttaagttcta ttttttttcc taaaatgtta ttcatgataa
    29701 taactcctac tattcagttt ttgaagatag agtcagtata catgaagagt taaaataggc
    29761 aatgtttttt tatggatatt tgtattgcta aaaatttatc ttatatattc attttgatta
    29821 tactactttt atttgtaaaa attttctagc aaaaccaagt gcttgcaact gattaagcgt
    29881 acaatttttt agatgttccg agcgtacttc aatcatttca aaggagttgc tacttaaatc
    29941 gatatttttt aaatcagtat caaaaaagct agcattttct aaatcattag tagaaaacat
    30001 tattttagtg agggaacagt ctacaaaatc tgcgcttgat aagacagagt gctcaaaggt
    30061 actttctttt atgtttgaac cagataaatt tacatagtcc attttacaat tctcgaataa
    30121 cgtgttccca atataacttt ccatcaattt agtacctgtt aatttacaat tgacaaattt
    30181 cacgcgatgc aacatgcttt ttgtcaatat acagcctgaa aaatcacagt tttcgaatat
    30241 acagtcggta atctccattc tttgaaaatc attggaagca aaaaatgcat acttgaaaat
    30301 agatttgtaa ataattggat ggcagattat ttggttttcg atgacctctt tttgtgaaag
    30361 gatattatac agttcaaaat cttcgttttc atagatatga aaaaaggatc ctttattcaa
    30421 gcttgcttca ttaactttag gaaaaatcat atttaattac ctccattttc ataaagtcat
    30481 attaacaaaa gctaaaccaa cttacattag cagaaaatga gataggtttt cgcctttttc
    30541 gataacgata gtgtcgctat ctcttgaaac gttcttagaa ttgccctgag agacacaaat
    30601 taggcgtaat tctaataaaa atcttagaat aaaaattttt actgatttaa tttagaatgt
    30661 ttttaaaata aaaatcgttg ccataacagt gtattgaaag gttttaacaa tccagtaatg
    30721 atttaaaaaa atctagatgt agcgtatact ttgtttatag aatgtagtgg gaagaaatat
    30781 atttttggga ggaaatcgtg atgtctaaaa gtgaagaaat agaaaacatg gtactaaaat
    30841 tatatgatct cgttttaaat ccagagatca aagaaaagga acgtatactt ttgatagacg
    30901 caaagacagg cttagaaaaa ggtcagtatt atcctaaagt cataaataat ttggaacgta
    30961 gtttacgtcc gttagcaatc aggggagaat tgtctaaacc agtatcaccg ttttatatgg
    31021 agatatcaac aataggaaaa tttgaaaaag aattaggtcg aggaatggct tcggcaccga
    31081 ttacttttgg gcatttataa aaacgagtta ttcatctcaa tgaattaaaa agtatagtca
    31141 atctcataat gcaggctagg ttcatttatt tgaacagagt ctgtattttt ttattctaaa
    31201 taaagaaaca gatgtttctt tatattgtat tttatccttt aattaacaca aaaacagcta
    31261 gtataaacta ataatgttaa ttaaaagt
//
LOCUS       DAFLWZ010000027        29535 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000027 DAFLWZ010000000
VERSION     DAFLWZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.027"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(222..1223)
                     /locus_tag="L1V38_001308"
                     /pseudo
     CDS             complement(222..1223)
                     /locus_tag="L1V38_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
     gene            complement(1223..2005)
                     /locus_tag="L1V38_001309"
     CDS             complement(1223..2005)
                     /locus_tag="L1V38_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315865.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            complement(2022..3779)
                     /locus_tag="L1V38_001310"
     CDS             complement(2022..3779)
                     /locus_tag="L1V38_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBN1315866.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            complement(3754..6585)
                     /locus_tag="L1V38_001311"
     CDS             complement(3754..6585)
                     /locus_tag="L1V38_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1315867.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            complement(6582..7349)
                     /locus_tag="L1V38_001312"
     CDS             complement(6582..7349)
                     /locus_tag="L1V38_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBN1315868.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            complement(7382..10501)
                     /locus_tag="L1V38_001313"
     CDS             complement(7382..10501)
                     /locus_tag="L1V38_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1315869.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            complement(10518..10805)
                     /locus_tag="L1V38_001314"
     CDS             complement(10518..10805)
                     /locus_tag="L1V38_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315870.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            complement(10859..11227)
                     /locus_tag="L1V38_001315"
     CDS             complement(10859..11227)
                     /locus_tag="L1V38_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HBN1315871.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            complement(11273..11785)
                     /locus_tag="L1V38_001316"
     CDS             complement(11273..11785)
                     /locus_tag="L1V38_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HBN1315872.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            complement(11796..12188)
                     /locus_tag="L1V38_001317"
     CDS             complement(11796..12188)
                     /locus_tag="L1V38_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HBN1315873.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            complement(12188..12526)
                     /locus_tag="L1V38_001318"
     CDS             complement(12188..12526)
                     /locus_tag="L1V38_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1315874.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            complement(12510..12836)
                     /locus_tag="L1V38_001319"
     CDS             complement(12510..12836)
                     /locus_tag="L1V38_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315875.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            complement(12833..13162)
                     /locus_tag="L1V38_001320"
     CDS             complement(12833..13162)
                     /locus_tag="L1V38_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBN1315876.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            complement(13174..13437)
                     /locus_tag="L1V38_001321"
     CDS             complement(13174..13437)
                     /locus_tag="L1V38_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315877.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            complement(13455..14378)
                     /locus_tag="L1V38_001322"
     CDS             complement(13455..14378)
                     /locus_tag="L1V38_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1315878.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            complement(14391..14993)
                     /locus_tag="L1V38_001323"
     CDS             complement(14391..14993)
                     /locus_tag="L1V38_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1315879.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            complement(15120..16046)
                     /locus_tag="L1V38_001324"
     CDS             complement(15120..16046)
                     /locus_tag="L1V38_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1315880.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            complement(16051..17550)
                     /locus_tag="L1V38_001325"
     CDS             complement(16051..17550)
                     /locus_tag="L1V38_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1315881.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            complement(17563..18807)
                     /locus_tag="L1V38_001326"
     CDS             complement(17563..18807)
                     /locus_tag="L1V38_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBN1315882.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            complement(18794..19327)
                     /locus_tag="L1V38_001327"
     CDS             complement(18794..19327)
                     /locus_tag="L1V38_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1315883.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            complement(19354..19578)
                     /locus_tag="L1V38_001328"
     CDS             complement(19354..19578)
                     /locus_tag="L1V38_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315884.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            complement(19585..19797)
                     /locus_tag="L1V38_001329"
     CDS             complement(19585..19797)
                     /locus_tag="L1V38_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315885.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            20147..20338
                     /locus_tag="L1V38_001330"
     CDS             20147..20338
                     /locus_tag="L1V38_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBN1315886.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            complement(20331..20672)
                     /locus_tag="L1V38_001331"
     CDS             complement(20331..20672)
                     /locus_tag="L1V38_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315887.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(20971..21438)
                     /locus_tag="L1V38_001332"
     CDS             complement(20971..21438)
                     /locus_tag="L1V38_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBN1315888.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(22030..22317)
                     /locus_tag="L1V38_001333"
     CDS             complement(22030..22317)
                     /locus_tag="L1V38_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315889.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            complement(22314..22523)
                     /locus_tag="L1V38_001334"
     CDS             complement(22314..22523)
                     /locus_tag="L1V38_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315890.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            complement(22520..22717)
                     /locus_tag="L1V38_001335"
     CDS             complement(22520..22717)
                     /locus_tag="L1V38_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315891.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(22714..23040)
                     /locus_tag="L1V38_001336"
     CDS             complement(22714..23040)
                     /locus_tag="L1V38_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315892.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            complement(23037..23318)
                     /locus_tag="L1V38_001337"
     CDS             complement(23037..23318)
                     /locus_tag="L1V38_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315893.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            complement(23331..23549)
                     /locus_tag="L1V38_001338"
     CDS             complement(23331..23549)
                     /locus_tag="L1V38_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HBN1315894.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            complement(23546..23857)
                     /locus_tag="L1V38_001339"
     CDS             complement(23546..23857)
                     /locus_tag="L1V38_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1315895.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            complement(24034..24348)
                     /locus_tag="L1V38_001340"
     CDS             complement(24034..24348)
                     /locus_tag="L1V38_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBN1315896.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            complement(24348..24647)
                     /locus_tag="L1V38_001341"
     CDS             complement(24348..24647)
                     /locus_tag="L1V38_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315897.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(24650..24811)
                     /locus_tag="L1V38_001342"
     CDS             complement(24650..24811)
                     /locus_tag="L1V38_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1315898.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            complement(24826..25185)
                     /locus_tag="L1V38_001343"
     CDS             complement(24826..25185)
                     /locus_tag="L1V38_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1315899.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(25182..26033)
                     /locus_tag="L1V38_001344"
     CDS             complement(25182..26033)
                     /locus_tag="L1V38_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1315900.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(26050..26883)
                     /locus_tag="L1V38_001345"
     CDS             complement(26050..26883)
                     /locus_tag="L1V38_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBN1315901.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            complement(26890..27576)
                     /locus_tag="L1V38_001346"
     CDS             complement(26890..27576)
                     /locus_tag="L1V38_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315902.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(27582..28328)
                     /locus_tag="L1V38_001347"
     CDS             complement(27582..28328)
                     /locus_tag="L1V38_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1315903.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            complement(28321..28662)
                     /locus_tag="L1V38_001348"
     CDS             complement(28321..28662)
                     /locus_tag="L1V38_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315904.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(28841..29530)
                     /locus_tag="L1V38_001349"
     CDS             complement(28841..29530)
                     /locus_tag="L1V38_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBN1315905.1"
                     /translation="MKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAENWADLFW
                     EDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKELKDQLP
                     SIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMVRNKIRV
                     ICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMPSTATMT
                     IIKQMELLEDE"
BASE COUNT         7925 a         6383 c         4678 g        10549 t
ORIGIN      
        1 attttgatgt cgtacaactt aaatccgcca tttattttat ccctgtcaac aaagctaata
       61 ctcatataaa atcgatctaa atttgtgatt tgataattaa cgttagctgt acctttgatt
      121 gttatttctt tccctacatc atctgttgta atatttgtac tatttgcttc caataatatc
      181 ttttctcctg gtgatgtacg atacaccaaa cgtaatttat caatagctcc tgtagttcct
      241 tcatcaaatc gaactttcgc actcagagta taggttttcc cactagcaag ctgaggtgta
      301 ttaatacgcg taaacataat aatgcttcct gtaccatcag aagtaaaatg tagcttttcg
      361 ttatccgaag ttagtgaccc gtggtaacca acgttaaaat cgctcgattt tagtttggac
      421 attaaattcg gattcccact ataatcataa ttcccgaagt cgatgctgtt actgtacatc
      481 tttttcagct tgccgaggtc gccgatttgc tgattggttt gattcatctt gtcttcaact
      541 gctttaagat tgttttgtgc cgatgtaacg ttttgagaaa cggtatcaat cttagtttga
      601 gtagcttgta gttgctctgt tacctcgtca acagtttgat caattgcttg tgtggctccc
      661 tctacaaatt catttatttg ttggtttgcc ttttcaatcg tagaatccac atttgttaat
      721 gctgcgttaa cagcatctgt tgcttcttgt ttgactccat caagtaattg ttgaaagtct
      781 gcaataaagt agtctgcttt atcttgcgct agtccgtcga ttgctgaacg cttcatacgg
      841 aaggtgaagc ctaagttatc acttgttgat ccgtctggat actcgatgta aacataagct
      901 tccaccatac cgttataagc tttcatcgct tctggcaaga tatatacgac ctgtccattc
      961 aagaagcttt cagtgatgag gtttttcgtg ataaaaggga ttggctcttt cgtgatcatt
     1021 ccatctactt catcatagat aaacatcaac aagcgcaagt tagctcctag caagtccgcc
     1081 ggtgtgccgt tctgttgttc gacgttgaac tctaacgcta tttgattatc gtatgattta
     1141 aatacaagcc ccgttgcttg caaatcgtag tctttcggct gtgtaggtac tttgatagag
     1201 ccttttttga tgacatgcgc cattatttca caccttcaat cttagttatt ttcacgttgt
     1261 tgctcattgc gggattggaa acattgccgg atgaaatatc taaagctctg ccgtttgaca
     1321 tcgttatctt tcgcgcttcg attgtcagct caaattcgat gaacgtcact cccgcgtctc
     1381 cattccataa attcgctttt gtaattcgcg cgtatctttg acgtttcact tcttctacaa
     1441 agtctccgtc accgtctgtg tagtggatac gaagcgtttg gtaacggaaa gtatcatctg
     1501 gcagattgac tgattgtcct tttcttaatt cgccttcaaa aagaacagaa gtagtgtaaa
     1561 cgcgccgcca gcctaacgag ttataaccct ctaccggttc gctgttatgt gtcattttga
     1621 tgtaaatttc gccgctataa cgagcaaaag cgacgattaa ttttctcgaa tcgtgatccg
     1681 cgaataccat catttcaaca aaactgtcat cttcaatccc gtcagggttg tctgcgcccc
     1741 atccggcttt ggttgcgtat ttgccgggcg gaatgtctaa aatgttcgga tatttttgtg
     1801 gtagcttata atcgcgtaac caacgcccac gcgcttgcat aactgtttcc ggtgtagcaa
     1861 agcccgcgtt gctttcagta gctaggacgt gcgcgtcgtg atccgagccg tcgtaatgga
     1921 tagccgcttg acgcaataac catttcacag cctcttcata actcatttct tcaaaaatat
     1981 ttggtttgct ttgaaaatct aacatttaat tgttcaccgc cttaatagtt ataagtgaag
     2041 tctctcgcgc gccctacgcc tttgcttgtc acttttcttg ttgctgtgtc aacttctatt
     2101 ttataaaacg ctaattcatc cggtgtatca acttggctag ctgtatgaga gaagccgacg
     2161 tcgcaaagaa tcatttttac tgttccaaac gccccttcga cttgttcgtg ccaatgcccg
     2221 cagaaataac ctactacaac gccggcgcct tttgtattca ttgcgaaggt ctttaatccg
     2281 ccgaacgaac cgtcattcgg ttgtcctaat ttagaccaat cgatagttac cggactacca
     2341 gatttaaacc cttctatcaa cgtgctaatc atgttttcat tgcgaacggg aaacttgctg
     2401 agacctaaag gcgtatgtcc tactaacgcc acatgatagt ttctcggaac gttcactaac
     2461 cattctccga aagcgttaat ttgtttggca ctgaaagctc ccggcgctgt atcgctgtaa
     2521 ccgtccacgt acttgtcgcc tgtgccgcct tcataaaaat cacaagtatc gaaacggtaa
     2581 attgctgcgt ttttatctgg gaacaacacg ccaccgtaca aaccgttcca atactcttcg
     2641 aagtcagcgt tgcataacat tccctttcgc ttgcgccacg cggggtcgaa acaagcgtcg
     2701 tgattccctt tgcagataat aaccggtttt tcttgtcctg ctaccgctgc gttagtgaag
     2761 cgtttgagcg tgcctaacat ggaatgtcgc gcgctccatt catcaataat gcctatatcg
     2821 ctgccgagtg aaccaagtcc gccgtcgata ttgtctccgc cgtaaatcat cacatctgtt
     2881 ttgttcccta atttttgaaa ttgagggatt gcgcgccaat gtcttaaata agaagcatct
     2941 ttgtaaccga cgccatctat acgcaagttg tgattatctg cgtgaatgtc tgtaatgaaa
     3001 gaaaagttaa atttgctgtt attaacactg ttgacaaccg tattcaaatt gcgcggcact
     3061 aggtcaacgt atttcatcgt gtcgtaatca aaaaagcgtg ttgtttctct aatttgtgag
     3121 ctgccgactg gcacttggta tttttggttt aaacgatcag ctaatgattc gtagtcgcct
     3181 ttagcttcat tcagaatgtt aatgatcata ccacctggat cgatattttc cagtatttca
     3241 cgattatctt ctaaccactg ctcccagtca tttttgccct gatccatgta atctttgaat
     3301 tttcttagca aatcctcaaa tgtccacaca tagccagagt cacgtaactg gcttctagat
     3361 attccagaaa tgactcgata ggtaaaatcc tgtgtgctaa attgttcact ccaagttcca
     3421 tcaccattaa gtgatcggaa actgaaatgt gcggtgtttt caccacccca ttgccagtca
     3481 ggctcactta aggtgtaaac aagccttgct tgcgctggac tgtattcttg tactttttgt
     3541 tcaacaggtt ggttttcgcc aaattttgtt gtattaataa aaaacggcac taggccctcg
     3601 aatgttttta gtttgccatg ttccaccact tcaacaacga acttttgcgt taaaacatcc
     3661 ccttgccgaa ttcgaaccaa atttattccg ttgtttggtt cggtggtgga taggaccatt
     3721 ttatgctgcg tttctgccat gactatccct cctttagaaa tcgatgtagt ctcttgcatt
     3781 gtggaaatga cctgaagaag atggataaaa ctcatccata aattgaaaat gaagatgttc
     3841 tccagtggat ggtcctgttg tccccatcag tccaatttgc tgaccagcag ttaccttctg
     3901 accttttgag acgtctactc ggctttgatg cgcgtatcct gtatacattc catcagcgtg
     3961 tttaatcact gtccaatttc cataccagtc aaagtaattt gcatcacctg caacaatcac
     4021 ttcgccatcc gctgaagcaa aaataggtgt attaggattt ccatttacaa ggtcaatacc
     4081 gttatgaaat tcttgtgctc ctgtgattgg agaagtgcgc cagccaaatt cgctcgtcac
     4141 tgtgattgga tccgcaatcg gcttcatata tccttttgat acaggaattt ccaaatcttt
     4201 gaacttgtca taccattctt gtgaccatgc cgtccgttct ggatgtggat cacgtggacg
     4261 ttcaaagtta gccacgaatg cttgtgctgc tgtgttgata tcggtcagat tcatgaattg
     4321 tgtccatgtg taaggataag cgctagttgc gatccattga ccatttggtg catgccacat
     4381 caacaattta aactgtgccg tgattgtgtc tggatcatca ctgatgccag cctttgtcat
     4441 taaattgatc atgtagacac gtccgctagt tgcgccagaa gaatcggtcc attgccatac
     4501 accataaccg aaccctggtg cgccattgcc ctcatcagcg gttggattag catctgattc
     4561 tccttgtgca tttccaagta aggctgcagc agcttgttgt gtaaaaccgg cacctattgc
     4621 cgttgcccaa atttgccaat atcgtttatc ccgatcagta gttacttctg gtgggtattg
     4681 tccgttccaa ccgttatcgt tccctccgga attgcctcct ccattagtgt caatttttgt
     4741 accgttaaca tagagttctt ttacatctag ccgtccatct atggttatat ttccttctga
     4801 aaaattgccg tcaccataaa gattatattt gcgcttatca gcagtaacat ctgctggaat
     4861 ttgaaaaata ggattccctc gatcgccacc gtccccagca ttaatggaaa aaatatagtt
     4921 tggctctttc cagacagcaa agccgttaat ccctttagaa ccataagtag atacaattga
     4981 gcccaagcgt tctccatgta catcatctag tccagtagac ttgacttgtt tttcaaaaga
     5041 aagttctccc ccctctgcca ctaattggaa atctttatcg tcaaatgttt ttaaagctac
     5101 cccttgcacg aggataccag acagaatgcc tgcgcgaata aaattagcat tgaaagttcc
     5161 atccaacgtc caagcggtcg tgctatcacc attgtgtaca tcttgaattg tttgccactc
     5221 acctttttta cattgtttga aagatatccc tgagttattt tggaccataa aaaagcgtga
     5281 tctaggaatg ttaggtccat ccatataaac agtttcatag atttctctac tatcactaac
     5341 accagcttca attccattta cccaataaat agaaccgcca ttatctcctg cacctcgcat
     5401 aatgtcatct tgatattttc caatctctgt cgattcgtaa aatgtcattt tgctagattc
     5461 taaactatta atattattga caatagaagc cgtttgtttt ctaacatctt gtgttaaatt
     5521 atcccctagt tcgatattcg tttgaccggt aagccgattg aatgtagttt tataaatacg
     5581 agttttatag tgataacctt tatcgtatct gtgaatagtc actgtatttc ctatcacatc
     5641 tcctccagtg acttcagctt tgaattgtac taacggtcta gcagaatcga ttaaggttga
     5701 ataagtattt ttaagtaaat ctgttggatc atctatatca tcaaacacta ctacggtttc
     5761 tcgttttctc attgatccat ctttttgtgg tatcccatac ttttgagttg attccggatc
     5821 ttcaagccaa ttttggcctt taggcttatc taaaggatca ccattcgact ttttccattc
     5881 aacatcagtg aattcaattc ttctaccgta accgtcacca acctcttcgc ctcgcccacg
     5941 acctatcatt gaagttgaga ttgagcttct atctatctct cttacaactg ttaatgcttt
     6001 actaccatat acgaaacgtg tattcgattc ttcgccaatt tgttcatata cttcgatcca
     6061 tttatccttt attccatcag aattcaaaga acacctaaag acaaattcca tacctaaggt
     6121 ttgcaattct ttcaacgctt cttttacaga gacatagtaa aaagttgcag ttactgttgg
     6181 taacattgct tctacgtgac caacgcgcca atttccttca gtaaattcaa tcaatcgatc
     6241 aagaacattt tttaagggct gcccactcgg cctaatatct ttgatgatgt aagcatctaa
     6301 ttcatttgtc gcaaatccta accctgtaaa ctctaatgtt tcaaatgggt cgctaacttt
     6361 agtaattcga tacaacgaaa aagacgactc gttttcacga atcgccatat atcttgcatc
     6421 ctctatttct ttatcatatt ttgtcgtaac gtaaagagta tctttcatta gatcactctt
     6481 atcagaacta atttcttttt cttgggagac ttcaatcaaa cttcttgtat tttttctttt
     6541 aataagtttt tgcaagtgat caaagaaata aactgtctca ctcaaattgt cgccccccta
     6601 tagaatattt taagcttccc attattgcta gttatcttct gaccttgctt aagataaaag
     6661 ttctcaaaat cactttctaa atcaatcata gaagtacaat cttctccgtt tacagttacc
     6721 tgctcatcgg aaaaatcaaa aaccaacacg tctcctgttt ttattgccgc gtcagttatc
     6781 gtgatatttt gttctccgtt tgtaattttg attgaattat tcatggataa agtaacttca
     6841 atttttcttg gtgttatagg aaactgtatc ggatttccaa tatagccatc actaacacac
     6901 tctttcgtat actttagtgg atccgcacag aatacattaa aactcgaaat aatcgagttg
     6961 gagtctcctg gaacagtatc agttgatgta tagcgaccgt agtaataata atctaattca
     7021 tcatgaaacc taatttccac gtcttcattc cggtataaat aattcaacag ttctttgaat
     7081 ttaaactgta gtttttctgg atctctatct tccagcttat atgttatttt tagtgttctt
     7141 gaaggtattt tctgatttgt aatgattgaa ccaatttgta tctcttgctg ttcaacttct
     7201 acagaaagca tttctctacc ttccaccgta agtgtttgat aaccatcaat caaatcttct
     7261 aaatacattc catcgtacat catggcagac gtcggaagga atcgtttaga actagtgaga
     7321 ttaatggttg tatctttgaa tgagtacatt ttattttctc gttgatccaa aatattccct
     7381 cctaaaattc cagattaata tctgcacctt cgcccatagc ttgtgaaata tcgtccataa
     7441 acaatctaaa cgattgtctt ccaagattga ttttaaatac agctggttta gtagagccac
     7501 ccatatttat tttatgttca acttgtgcac caatgttttt atttgcattt ttcaaatttg
     7561 cagctatatc tacatcagaa tttgcattga aaagttccgc gataaagtct gccatacttc
     7621 caacagtatt ctgtacgtca ttgaatcctc ctgtcagacc tttattcaga ccgttcataa
     7681 tagcctgacc agctggaatc aatagctttc tatcgtattg gataggtcct ttgtgttcac
     7741 gaatccaatc accaatacct ccaacaaaat cttgcacaga tttccatgca ttttgtaacc
     7801 cttctagaaa actatccatg atagcttttc cggctgctag taaatcgata tttttcaagt
     7861 tatcaaacca gccagttact ctatcaaccg tgtcactaac agcatttact aaattatccc
     7921 atgcctcttg agcaccattt actaaattgt tgaaagtatc tatagtacct tgttttaggt
     7981 tttcccatcc ctgaatgatg ttatctttgg ttccagtaat taaatcacca atccaagatt
     8041 tgaatgaagt ccaaatgtct ttagcacctt gaactgtatt gttgaataaa tctatcgttc
     8101 cttgctttaa gctgttccaa ctttttataa gagtttgcac gatattatta accgtttgga
     8161 aaaaccattg ttttagatta ttccaaagtt caattgcacc atattttgta tcaatccaag
     8221 tttgaattat ggagaatttt agatttatcc acatttgaat tgcactgtat ttaatatcaa
     8281 tccataaatt agtaaaaaat agtttcaaat caatccaaat catagtcgct tgataaacta
     8341 cttcattcca aatattagaa atactttgta tgaatccagt ccataaacta acggcactat
     8401 ttactattgc accgatatat tccgtaaata tattttttac agatgtccaa atatttacca
     8461 ctgattggac aagtgtgttc cagattagat ctaaatcctc tttcatttgt tcgaagtcac
     8521 cagtaattaa atctataata aacagtagtg gcgcagctat taaagactta atgatttccc
     8581 aagcatttac tattatgttt ttaacctcag caaatatact tgttattgct ttcactatat
     8641 tagagaacac atctgaaaag ctacttacaa atggaccaat atattttagt ataaaatcaa
     8701 aaccagattt gattttactt gtaattgttt tccatgcagt agatatagta tttttaaacc
     8761 cttcccattt ttcaccagca cttgaaacta aatcatcaat aactgatatg acaccttctt
     8821 ttaaactatt ccaaatctct gaagcagagt ttgcaatact tgaccataaa tttgaaaaga
     8881 actcttttgt tccagtccat ttgtttttaa tccaatctgc cgctttccca ggggcttctt
     8941 gaactgtagt ccaaacattg tctgcgcctt ctttaatgga cttccataaa ttgttaaacc
     9001 attctcctgt agatttccat gcattctgaa tccattctac tgccgagctt acagcagact
     9061 tgattccctc ccataagcca atccaaaagt ttctaaaatc ttcactcgta ttccaaagat
     9121 agatgaaacc tacaacgagt agtgctaccg cagctataac cagaaaaacc ggatttgtaa
     9181 gaagacccat tgctttactt aatccactaa acaattttga actttcactt aaagctttaa
     9241 aagctacttt caccctattg atccatataa ttactgaacc aatcataaaa attaacggtc
     9301 ctatagcagc gacaattgct cctatggcca ctactaattt ttgagttgat tctggagcac
     9361 ttacaaattt ttctactaag ccggatatgg catctgctac ttttttgatg gatggtgcta
     9421 gaatcttttg aattacaata gctgctgact caaaagctcc aaacatttgc tcgatggaag
     9481 aattcatatt atcttgcatg gtccgagcca tatcgtcagc tgcaccatca gaatctttca
     9541 gagattttgt taatttgccc aatgaatcag gtcctttatc aatcaaagcc atcatccctg
     9601 ataatgattc ttgcccatat agtgttacta aagcattttg ttgttgttca ggcgtcaggc
     9661 cttcaaaagc ttttttaagt aattctactt gagtttttaa aggtttcatt ttaccgtcag
     9721 catcataaaa cgaaacacct aaattatcca ttgtatcttg catagccttt gttggccttg
     9781 ctaacctaga caatgctcct cgcaacgttg tacctgcttg agaaccctta atgcctgcgt
     9841 cactcataat accaatagct gctgcagttt cttccaaaga aatccccatt gaattagcta
     9901 caggagcaac atacttcaat gcttctccca tgtctccaac ttcagcattg gtatccgcag
     9961 cagcacgagc aaatacatca gcgacatgtc ctgcttcact tgcttctaaa ccaaatcctc
    10021 tcaaagcagt agcagtattt tcagaagcta gagccacatc ccctccagat acagctgcta
    10081 agtctaaaag acccggcatt gctttcatga tttcttgtgc gctaaatcca gcagaagcta
    10141 agttttccat tccagcagct gattcttttg cgctaaaagc agtttttgct cctagatcaa
    10201 tcgcttgctg tttcatctgt tcgaatgtgt cgccggttgc tcctgatata gcttttacac
    10261 gactcatttg tgcttcgaag tcgccaccaa ctttagcagc tgctacgcct actcctataa
    10321 gaggagtggt aatatacttt gtcattgcgg caccagtacc ttgcatcact ttaccaacag
    10381 cggttgtcat actatttgaa ttcttttcaa aagttttaac agcatcttgt gcatctttaa
    10441 aagtctttac aaatccacta tctgtggctt ttaataaggc ttcaacagaa aattgttcca
    10501 tgattctcct cctttcctca agagttagct ttagttagta agctttggaa ttttttatct
    10561 tgttttgaaa gttcggaaac tcccatgatt gaatcttcga ttttttgata attgaagaat
    10621 tcttcaaagg atcgatatac aggaactgtc tttttgccta cttttttctc cgcttggact
    10681 tgctgatttg cccacgctaa ttcgtgaatc aacttttctt tgtcaagcca agataactgg
    10741 gctgcagtca tacgaatgtt gtattcatat aacgtcattc tttcgatatc tgagatattg
    10801 gtcattccca aatatcgaaa agaattgata agaatttgtt cgtatgccag tgcagaatct
    10861 attccacttg ttgtttttcc gcttctttca atttctgatt caggtttcgg accgctaact
    10921 ttcccgcgtt cgactccgcc aattctttta ggacttcatc aaacaatttt tcaatgtctt
    10981 taacttcatc gatgtaatca tccaattcat ctaatgtaat agattcatct tcagttctat
    11041 ttgctatttc cagaactcgt gataacgtgt taacgttata agaacgtagc tctggtaaga
    11101 cttttgcgga gagtcccatt ccaaattcca tatttccatc gacgaaaggc atcactttat
    11161 ctaattcacg tacaaattta gtgccaaatt taaacgaata ttctttacct ttaattttta
    11221 atttcaatgt ttttcatcct cctaaaataa aaaagagagc atctaagccc tcttatgctc
    11281 ctgtcgaagt tgctttcacg gtatctttga atgcatattg aacaacatcg gcttgatctt
    11341 ctgtcaaggt tgcataacca tcttgaccaa caccatttac tgcaaatgat aaacttaatt
    11401 caacgttatc ctctgcagca gccgatggag taaattcaga cacatatgct tggtaataag
    11461 tagctttgta cttatttgca ttatcatctg ttccctgttc tgctttatta atttcccaaa
    11521 tttcaatgat atccccattt aataaagctt gtttcatttc atctacatga gaatctcctt
    11581 tagcaactat tgaagtagcc gaaaaatcat attcaaccgg gcttaaactt tgaacgtttc
    11641 catcttttgt cactgtagag tctgaatctc ttgataaacc attttcgtgt tctgtttgaa
    11701 atgccatttt ccaagcggct tcctgagttt cttttttcaa taagcgataa agcaaaatga
    11761 catcaatacc ttttaatgct tccatgttct tcctcctatc taattctaaa ttcaagtgtg
    11821 acaaccgccc gttttagcgg tgtattcgtt gttgtgtcgt ccatcacttg aattccactt
    11881 gcttgataat ttaaagccca ataatagcct tctgtggctt ctatcaatct agcttcatta
    11941 aaaagagcag atgccatatc tgacaactgc tttcgtttct tctgtaatcc ccaaacggat
    12001 aaaaccacaa tcacagaccc tttaatgtca gttttattta cttcatggat tgtctgagtg
    12061 ttctcaaatt ccacaaaagg ataaccaaca tcctctaaag ttttgtaatc gtatgtttta
    12121 tatccaagtt tgttttggga tattttaaaa agttcatcaa aaattgattg atctcttgtc
    12181 ttaatcatca tttcaccaag gctttcattt cagccataaa tttgactttt tggtaattaa
    12241 acgctggtct aacataaggc tgtgccgaca taaatcgagt gccatattct acataaggtg
    12301 cataatctgc tgtcggtcct acaataccag ttaaaccagc ttctaaaaga ttcatgttta
    12361 ttgatcttcg taagtaacct gtatccactg gcgcaccttt ttgcattcgt tcagtcattt
    12421 cagcagtatt acttttcacg actttttgaa cgtcattaag cgttgctgct tttttcagat
    12481 gtcgcatcag ctgatcgatt cctttatatt caagttgtgc cttcatcaag aaccacctct
    12541 tgcacaatta aactatttct atatgctgga tttctagctg ttttttgttg ccaagtcttt
    12601 ccttcaatct cgatatagtc aaatgtaggg atagaaaaaa gaggctgcgt cctaatgacc
    12661 ttcgcccctt cttccacact accaaaaata gtcacacttc tatcagtgcc aatatctgtc
    12721 acgtttgcct ctgttcttgt tctttctggt ttgccttcaa cccactcacc gagatctgga
    12781 tcatatttag agtcagatga acgtttaaca aatataattt catctgtaaa tctcatacaa
    12841 atttaaacct ccctcgcttt ggcttgtaca actcttcctg atctttacgc ttaaattcat
    12901 caatctcatt ttgatactct gaaaaatccg agtcaggaaa agccatagat aaaccttctt
    12961 gagaatatga ctgcatacct tcttgaccaa ttctattgaa tcttttcaac gatacttcat
    13021 atacaactgt ttcaaattct ttaggaactt cttgcgtatt taacaaggtt ttcatacgct
    13081 cattcgttct tcgctcaata acttcaagct tttcatctat tgttccttta agaagttttt
    13141 taatatcatc tgcaatcatc atatttttac ttcctaacta gcaggttgac ctgtcacatt
    13201 gattgaagta gtgaattctc cagaagtaaa tgtgaatgtt gctgaccctt ctgctgcaat
    13261 cgttccatca aaaccaccat tttcattttt ggtcactgtt gcgatagctc catcacttga
    13321 agttgctgta gtagctgcaa caacagcagc tgcatcgcta gcatctgcag gcacagctga
    13381 aatagtaaat gttttagtat cgcctacttt accggtccat gtcttttgat ttggcacaat
    13441 accggtagca ggcgttacgc ttttggggaa atcttcccaa atgcttcatc ttttacaatc
    13501 ataaatccaa catccattgt tgcacgcaaa gcaatcagtt cttgctcaaa caagttaact
    13561 ggggttccat cttcattagt taaagtagac aattgggctt cttcagaaat cttaaatgaa
    13621 atattatatg ggatcccata aaacatgtaa ttaaagtctc cagcgtaaag tgttccttta
    13681 tctaaagact taaggtctac tactggtaat ccgtcaattg tattagtaga gcgatcataa
    13741 ataaactcaa catttgaccc gactgtttga gctgcagaac gtaattctgt acgatttttt
    13801 cggtttgaaa taaacgcatt aggttcgaat tcattttctg ctaacttgtc ttctaaggct
    13861 aggatattat cataagtcaa tccgccttca accacattcc ccgcactaat aactgatccg
    13921 tctagtgact gaggaaatgg gttttcttta tttaataagg cagctgcatc aaatttttta
    13981 tagaaagctt cagcaatttt tggctgcatc tcctcaaaga aatctgataa tttataattt
    14041 aaatattcac gagaaaccgg aagaatgaca ccgagttttt ttgcagtcat cgtagcttgc
    14101 atccatttag gtttagacgt tttaattttt tcaccttcac ccacccagta tgcgcctggt
    14161 ccttctgcaa agtattcaaa tttcttttct ttgtcagtca tttcttcgta ttttgctaac
    14221 tgcatgatct tagaattttc cataacttca ctcaaaatga gcgtattata tttatcagga
    14281 atttttccct ctttcgtttc atataccaag acattatctg gatcccatgt ttgagcaaac
    14341 atttgcaagt tcattggtaa aagttgtttc tttttcatta agttttcctc ctatttgata
    14401 attcgatttt tagcagctag tttagccact gtttctttag tatttttcga tgctgtaaat
    14461 tgtccacctt catttggtgg tgtttgtctt gcgttttctc tcttaatcaa agaagcaaag
    14521 ttagtgatga ctgctacagc ttgttttgtg gcatctgcat catcagaaac aatcagacca
    14581 agtaaatcat catcgtgtgg taaatttgca tctgtcagca ttttagaagc ttctttcgtc
    14641 atttcagata gtgcctgtcc acgctttaat tcagcgattt cagcttcttt ttgctccaac
    14701 tcatgctgta gtttttcttc cgcattcatt tttgccagct ttttagcttc ttcttttttt
    14761 gctgctagtt ctttttccca cgctgctttt gctttattcg tctcagcagc gatcattttc
    14821 gctacttcat cacgagaaaa tgttttgcca gtattgtttt cttcttttgc ttcgggcggt
    14881 gtctcttgtg agccagctgg taggtttcct tgttgtccct catcaccaga tccaccatct
    14941 cctggttcag aaaaaaattg taagttcatt ggcataaata aacgtttttt catgattaat
    15001 cctccacggt tacgccgcta cccgataaat ttgaccagtt acgccggtca gccgaaaata
    15061 gctttctctt taacgcctgt aagctgtaag aaggcacaat aaaaagccgt taatttgtgt
    15121 taacggcttg atattcgttc tatataaggt gctgtactgc atcgacaaaa tggatgcata
    15181 ttaggagcgt tacttcctgg ctgcatatcg gcaacatcaa aaacttgatt atttaacggt
    15241 atacatagtt tgcacgccgt tggttctgct atatagatgt actgggtaat gcctgcatct
    15301 ctataacttc gttcttgaat ccctacctga actctagtcg tttcagtcac catcaaacgt
    15361 tgagtgttga acttagtgtt ttctcgtcct tcagctgtta aatattctgc caatttagat
    15421 gcaagttgct tgggattttt ccccatcgtt atacttctga ctaacaacct atctaattct
    15481 gatttcaatt cagattgata catccataag cgatcactaa aagacacgtc atcactcaaa
    15541 aaggagctgt ttattactag ttctatcagc tttgcatatc cacttgaagc aatagtcatt
    15601 tctaaaatac cggcttgtct cttcaattca gctaaaccag cttttgttaa ttcattcgaa
    15661 aagtacttat ccaattcatt aaacagtgaa atcaattcaa gcccgatatt agcttttaag
    15721 agctctaatc tatttacacg catcgtaaga ttgtatagct ttaattcttg gtttgctgta
    15781 ggagaaaaat ctttctcttt gacatacttc tttgctttgc gagcgaatgc tttgacatcc
    15841 atttcactag cacgcttcat cgcttcgcta cgagtgattt tctggccatt ggagaaactg
    15901 tcccactgcg cgtctatttc tttttgtatc gcatcttgtg cgtattgcat gcgactttta
    15961 atttctgcca tgcgcttttt atcatcttta atttgttgct tttgccattc cttttcccgt
    16021 ttgatccaat attcttggga gttcatttaa tcacccccct gtttcatctt ttttgttgtt
    16081 aattacttct tcaccatctg aatcaaaaat gccaatctgc ttttgcgttt ctttatttac
    16141 tcgtttcaac tctgcctgta catctggaac aaaagaagcg agtcctaaga tcgtctcttg
    16201 actgagttca gctccagcat caaccaaaga tttcaactct tccagaatgg ctttaggtag
    16261 attaggcgta aatattacac gtaagccttt caaatcggag ttatccattt cagaaatact
    16321 tgattttagg ctaaataaaa gacgataacg ccgcataagg ccttttttga atagcctttg
    16381 ctttgttgcc gtcatttgtt caaatccaaa taatttatat ttcattgctt ctcccgattg
    16441 cactccggaa aaattgtcat cagtaagatc aggaaccatg gatatttcgt gaatatcctt
    16501 gcgtactctg tatttgtatg cttctacacc gttcacatca tattgtttgt aaatatatcc
    16561 tgcagtcaca cttgttttat taccgttcac atcagttcca gactcaagca aaagcatatt
    16621 cgcttctttc tgcttgatgg cgtcctctgt ggatagtcct gctgcttcaa tatcaccact
    16681 aataactaga agagcatcgt ttagatcagt catataattg gcggtatcag actgccctgc
    16741 atcgtataga tcaatcaaag atagtacatc ttcatacaag cccatccgaa aacgattagg
    16801 agaatactct gtaataggta cctctttata ttcatgcggt tcatcctggg gattctttaa
    16861 ctcaattgct gttagtgtcg tctcatcata agtgatactt ttttcttttg tgtatacgat
    16921 tggttgaatg tactgtttat cagcatcctt gttgaatctt gtcttaggat accgtacagc
    16981 caaaataggc tctcgtttta ctgtagtatc atatacaaca aacgtttcaa atacattagc
    17041 caaatcaaca taatctgtat catctgaatc tcgatagata atctcatagg ctctcccata
    17101 cttatccata tcaagccaga gttcagcatt taacccatct atgtcattat tagtattaaa
    17161 ctcttcgatt tctttttgtt gatttgtgtc ctcgatttgc acttttatag gattgcctgt
    17221 gttgtaccca acatcaaacg tacaaagaac ttttccaaag ttatgtgctg atcggtgatc
    17281 cgctttttct ttttctctgc gcctacggtt atccatgata tttgtatttc tagctttata
    17341 ataatcatct aatacactta gcctttttac ctgatattca tgatgatgtt ttatcattgc
    17401 tgctaaagta tctaaatcgt taagtaaatc ttctgctgag ctaaatctat agtgaagatt
    17461 tgagtctacg ctaaacttta cataatttgt gttcacgtca ttagaataat gtatatcagc
    17521 tccgtattca aactcgttta ccttatccat ttttcacact ccttaaaaca tgcgtttaat
    17581 acgtttaatc ttttcgttga cattaacttt tggtttctta agaagctcat gagtatatat
    17641 cgcatatcga acggagtcta gcacatcatc atattctttt attggctcgc cttttttctt
    17701 gtcccaaatg tattgataaa tttcatcccg aaatttcatc actctatctt gacagataaa
    17761 caatttatct tgtttaaatc tcttggcgac ttcctcaact ccagataacc gtgctttatg
    17821 agcattttta gcattaatct tttctcttac aaacctagcc acatgctccg gtctcgcaga
    17881 gtcacaataa aaaggtactc gtaagccgta acgctcttga atgccttttg ccacatctac
    17941 ccaataatca atctcttcaa attgagtagc atgttcttcg attaaataag ctgttccgtc
    18001 atccgtttca cctataacta cgattgaacc ccagtgttca tatccccagt caacaccaca
    18061 ataaaagttg ctcaaaggtg gtaagtcttt tgactggatg tagtgcttgc tagcatcaaa
    18121 atcacgataa acgacacctt ctgcagaaac ccataaacct ttgatatcac gatcataaaa
    18181 catgccgctt ggtgttgatt ctttaatatt gttacgatat cgttcagata aaaatgtatt
    18241 atcatctaat tcaaagtgga acgattgaat atttttgctt gaattgtcga tatactcttt
    18301 ctttagccag tgttccgggt tgtcagggtt tgtatcagct agtattctcg ctcctgttcc
    18361 tgaacaacgt gaaacgattt cagcaaatac ttcttgtcta gctagcgatg cctcattgat
    18421 ataagcgcca tatgctgtca taccacgaat tgcgccaaca ccgccaatgt ttcctgtata
    18481 agcttgtacg accttaacgc caaatagctt aaagtttcca tgtttatcga atttaggttc
    18541 tatgctgtac atgttgtata gttcctgtaa gatgttcttt tggattgttg cacttgaaac
    18601 tcctgctagg atatacattg gttccttaat gtcttcttca tcggcaatct ttcgcacacg
    18661 tcgcaattca aacaagaaca aatcattgtt tatttttgtt tttccagaac gttttgctcc
    18721 atgtaataaa gtaataaacc aatcattctt aatggtttta tttaacacgt cgatttgctt
    18781 tgggttataa atatcaacta gtgccatcta attcaccact aatcttttct aacaactcat
    18841 caagtttttc ttcggtagaa cgctctgagt ttatctgtaa ttgttctaat tttgcttgca
    18901 ttaattttat ttctgtttga gctttttcta attgcgtttg tgataacagc gatttatact
    18961 tcaaatacaa atccaaggct ttcaatttgc tttctaaatc tggtgtatat tcatattgca
    19021 tatgtttaat aaccttgttt ttctccaagc ggtctatttg cttgctcacg cttatttgta
    19081 cttctccttg ccaaatatct atcaattcat ttaaagcgtc ctcggcactt aatttgcgct
    19141 tcttttcgat aggatttagc cgttcattaa tatactgtat tatgttaggt ttagttaggt
    19201 tttccttacc tattactctt gctgatcgtt tgctataacc tgctttaatg gcggcttgag
    19261 tagcattacc accatttttt atatattcat ccgcaaaagc tttttgtttt ggtgtcaaat
    19321 ttaccacatt caagccacca cctttcaatt ttattaacaa tatctctcaa tatttgtctg
    19381 tatgttctgc tcactaaaat atccatggcc gcagtaacga agattgtact tatcaatctc
    19441 ttttggcgta gcttctctgg tcatttcaat gatggagtac ttctttttaa tctggactga
    19501 ctggacaact ctaattggat catctgcgtt tggttgcgga tatttatttg ataatgatac
    19561 ataccagtag ttcctcatta cgtatcactc tttctgttgg ttactggcag aaaaggttcg
    19621 catcataaat tccatagcct gtgcgtcatt aaatccttgc agaataagct gatcgtagaa
    19681 atacttagct tgttttgcga ttaacgctaa gcttttttga gtttcgtaga atgtcgcctc
    19741 cattgttttg tttgcttcat tcgttttaaa caactctctt aattggtttt cgttcatttt
    19801 tttactcccc ttccaaaata aaaagaccac tcgatgagtg atctaatatg taaaaactac
    19861 acctcataaa cgagatgcag ttatagttct atcaagcaac ctacaccgat tccatcgatt
    19921 actatcgacc tcgccttgct cgtgtacttt gagcgcccat ttccaaccct cagttgccaa
    19981 agtcactggc aaggaatcga accttgcatg gttgccgaag cattgaccta acacacatgc
    20041 ttagcgtcta ccctttccgc cacagtgaca aattaatatt gtgaaaataa atactaagtg
    20101 tataatttta tttatcagcg agtggtccgc tgaaataaat taaaaggtgg tgaaaaattt
    20161 gtactttgtt ataagagaag caactaatgg ccaatattac ttcgttatta agtccgataa
    20221 caatgaagta gtagcaacta gcgaaacata cttgactaaa tattccgctg aacaaaccat
    20281 taattctata aaaaacggaa tcaccaaaga ctctcaagtt atcgatgtga ctaaataaga
    20341 cgactaactt catttgctag ggagttcatt tcagctgctt tttctaccaa agcagttgag
    20401 atactttcta gcttttctga tttaacagaa ttaaatactg gcgtcttgat actaatcgat
    20461 acatcttgac gaggatcagg actcgttgct ctattttttt gcaccactga tctgtacttt
    20521 tctactgaat gatactcaat tacttgttct aaatgttttt tgtactcttt acatacagct
    20581 tctttttgga tcaattctaa acgttgttgc tcaataatat caatcaaccg ttcccgatcc
    20641 ataccttgat actttatttg ctcgacttcc attcgttttc cctccaatac ataaattaat
    20701 aaacagcaac ggatgataga taataagaac aatttagaag gagttggaat tcacatcctt
    20761 attcttaata tttccgttgc tgtctatcga agcttaattg tgaaacaata ataaaacgat
    20821 gttcctttta ttattatttt gtctcagacc tatcactaat ctttcgacac tatcataata
    20881 aatcatttac caggtaagtg attggtataa aaaaggtata aaatggaaac caaatgggta
    20941 atcaaagggt ataaaaagtg taaaaactgg ctacttaaaa gcaaccagtt ctaacgatga
    21001 agcaaattgg atgataattc tgtttgattc tactttaacc gattcttcgc tagtattatt
    21061 cctttgagca gttacataaa tgggcagacc attgatataa cgatcataga atatcttctt
    21121 gcgcctttct gttacatcag gtttatgcgg atgctgaatt gctgaatagc cacgaacaaa
    21181 taatttgtgc aagtactcaa attcttcttg cgcttcctct ctctcaatca tcattcgttc
    21241 tgcttcaaat gtattatttg ctgtagaagg tggaaccaag gagtaagatg ccgttacttt
    21301 aggctcccga ggttgaccta tcctacatct agctgacaga tatgctgaaa gaaaaacacc
    21361 aacattatgt tttgtgcgat ccatatccac atcttttgcc tctggtgtct catacttctt
    21421 tacatcgaaa agtaccatcc attgattcct ccatttatga tataataatt gtgtcagaat
    21481 tattaattaa ggtcggagga atccggcttt ttttataccc atgcttatgc taagcttttc
    21541 aagtagcgag gttgcactcg ttacccatat acatgttgag ctatctggcg gaaaacagat
    21601 ggctcactat ttcaatattc tgctaaggac agccagtggt cggctgtctt ttttatattt
    21661 taatgagaag ccttacttat ttttttatct ttattacgaa aaatgatatt atctattgat
    21721 aataaagcgt ataggagatg gttgagtgac tatgtggagc atgctgttat tttggattcc
    21781 cgtttgtatt ggtatcgtcg cattttgtta ctttgtcaaa cactctagaa caaataagct
    21841 cctcatgtta tcttttttac ctatagtatt ttttattgta caaattgtta aatataccta
    21901 tattgaatcg caagaaatat tcatttttta tgtggtaggt ttatttatct ctgtggtctt
    21961 tttcataatg atactttcct atttttataa aaaataaatt tttctcttag aagtacattt
    22021 tttcgctgtt tatatagcct tcatatccac caatctcgct acagctaaat tctctttgct
    22081 tttcgctaac cacttatcac attccatcgt gttttcaata cgaatgatcg ctgagtgatt
    22141 atagacgtgt tctacatatc cacgaaatgg atagatgaac ccttctgctt cgcagcgaac
    22201 catgtcaccg actttgaatt ttggtttctt acgtttttta ggattctttg tcggcatatc
    22261 tagcattaaa ccgccgatac catgactact agcgtaaaat ccgtctttta atttcatctt
    22321 tctacctcct catgatcgac agtgaccagt tcatatactt gtgttaatcc accaagtcgt
    22381 cgtgaaactt ggttagcttc ttcgaggcta tcaaaccatc tcgcactttg gagtatgtct
    22441 acaatgaata atgtgttagc ccctatagag cgttcatcac ttctataaaa tttattcccg
    22501 aactttacta cataaatctt cattctgctt cctcctcaat cgtccaagca tttgtaaatt
    22561 tctctaagct tattagttca tcttcattta aatatccgta accatataag gattctaaaa
    22621 ggtcttcttt tgaatagcct ctaaaatcaa gtctgagacc gcttaggatg tatacatagg
    22681 ttttatttcc ataaaacttg attgtgtatg ctttcatccc acttcctcct catcgatctc
    22741 tatctcgaca tctctgcctt ctaaaatctg tttggtatca atataggcta cgagtatttt
    22801 tcgattttgg cttaaagcaa tatacggatc aatcaaagca acttctgcgt gtagacgata
    22861 ataagcaata caatctattt ctaaaaatat caaacgatca atagcatcat taatcataaa
    22921 atctgtaacg ttttctgctg tatttaaacc atctgcatat ttaggcagga cttcattatt
    22981 gatgaactca gctacatgtt ttggacataa atcagtcagt tcttgttgtg tatagttcat
    23041 ttgctgtcct cctgattaat atatttcctc aaactacgta tccctttacc acgttttttt
    23101 gttttgcgct caatccacgt tcctgtagtt ccccagtagt caataattcc attatgggta
    23161 ttaattgcaa attgatgatt gtttggataa tgagtaaatt caaatcccaa ggtttcaata
    23221 tttttagttg ctgaattgcc catctttctg acatgttgtt ttctacgttc ttttagatgc
    23281 ggtttaatat ctttccagta ttcgcccata tcgcccattt cgctgtcctc ctatctcctt
    23341 gtccacaata aaaaccacat caactcttct gtcgtaccgt ttaaataaag atttatttct
    23401 gcaccaatcg caactaaaat tccgacaaca aacaaaataa tccctactgc tgtatatttt
    23461 ttgccttttg cactctcgta aatgaggtat gctcctaaca tcgctagtaa gccgccaatt
    23521 acacaccaaa atattgttag gctgatcatt tgctgtcctc caaatcactc gacttcacga
    23581 atacaccatc taccattttt cctgtgcgtc ctttgatttc gttgtatgct tggttcagac
    23641 actcgtacaa atccatatca ttttgcatag ctaaaataat caaggttact actacatctc
    23701 caattccgtc tcttaaacca tgttcatctt ttctagctag agaagcggca acttccccga
    23761 tctcttcgat cgtttttaac atttgcttgc tggaatcagc ttgatccaat cccttatctt
    23821 tagcccactg ctctactttt gtgattagtt cgtccattat tcattctcct ttatatattt
    23881 aagttggata atacaacttg taacaaatga agctaatgtt aaaattgtgc cgattggtgt
    23941 taaaaaaccg ctttttatcg cattaattaa tatagctaca aatatcgtta tatagaataa
    24001 aaagtgaatt gacgctaacg ttgaattaaa catctagtcc tcctcgaaat actcattcag
    24061 tatctctcta tacttttcta caaatttgaa acgatcctga tgaagtttct tgctccaatt
    24121 tgtttgccga tccagctcac gcatctgatc gaaccctttt tgaatttcgt tgtaataaaa
    24181 ttcaatgttt gctgctgctt tccaatgcct gctacttcgc actcctgctc ctgtttcagc
    24241 catttccaac ttaactaatt ccgctcgttc ttttgctttt ttatctttct gaatcttcat
    24301 catgattttc ttgaggatga tatcactgta ttgtgtaatg agatccatta tttctcctcc
    24361 acatacctaa actgtcgccc ctttgaatca atccataagc tcctagctct atcccagatg
    24421 atgtttttgc tcagtccagt aatttcagat aactgttcag ctgtacccgt tactagaatt
    24481 cgatcaccat gccagattgc aatttttctc ggcgttttcc gtttaggctt ttcagtccac
    24541 attgatttac cgagcttttg gacttctgca actatttctt tgtcttcttg ccaattctca
    24601 gaatgtgtca gttcaatgat tcgtttcatt gctgctttct tacccacgct cattcctcca
    24661 atctacgaat ttcccttctt aaattcacta tgtgcaaatt gattgccttt ctcgccgttt
    24721 cattgaccat cactgccttt atccgttcca gatcgtcaat ctcacgttga aggcttcgaa
    24781 tacgcatttg aatcacttct tctgttgtca tgatggacca cctcgttaaa aacgctcttc
    24841 cttgaacgta ttccgatatt ttttagctaa tatcaacggc acttgatatt gatgacagaa
    24901 caactttgcc ttgatcttaa agtcttttgt ctgcattcct ttgacatcta cgactttgac
    24961 aagtttgccg tttttataaa atgtgaagtc gggaatatac tcgatcttgc gatacttttt
    25021 tccatctagt tcaaatttcg gcatcagctc aaatctttcc tgaagtttta ctttccagcc
    25081 gttcgcttct gcttgccaca aggctaaatc gtaatactct gcttccgcga tagaatcaaa
    25141 cttgatacct cgatgaacag ttttcttatt acggtattta ttcatgcgat actacctttc
    25201 actggtttta tgcgcttgtc tgctgtttgt tggaatttca gcgcataacc ttctgaattc
    25261 ttaaatattc tagaaacaat tctttcgccg taggcttctc ttagttcagg accggataag
    25321 tttgttgtga tgatcgttgc cttgttctgt ctggcttcta agagcgtgtt taacgtgttg
    25381 tttgtaaact gcctactatt tgataccccg ctacctaatt cagctccaat atcgtcaaaa
    25441 accaccaaat cagttgtttt gatatcggct ataagcgatc cttcaatttc ttttctcagt
    25501 tcagcattgt tataagaaaa ctttatttgc tctaataact cttgatagct tataaaaagt
    25561 attttcttgt cataatttga gcgctcaagt atttcccaag ctgtcgccat tgacaagtgg
    25621 ctttttccgc ttcctgattt ccctgataga atgaaatgtg caggatggtt cagtaagaca
    25681 tcatttacaa agcttttagc tctttctaaa gcaattttcg tttcttggtc cactacgtga
    25741 taattctcca ttttgcattt aaacaaagtt ttatctgtta ataccgaacc attttgaaaa
    25801 aaactcaacg ctcgtgcttt taagctgtcg ttatatatcc gttcggtctg tatatcctct
    25861 ttcacacgta acgctttata accacaactc atgcatgttg gtttacaacg ttctgaacca
    25921 tccttatttt tagctcgcca actatacaaa ggttcgctac attctggaca tttcccgctt
    25981 tgcactaata ctcttcttat tagtttctcc atagcatttg ctaggctttc catgtgatgc
    26041 atctcctttt taaattggca agtcgtcata ttcactagga ttgctgtact gtagtttttg
    26101 actttgcttt ttatgattat tcttgtctgc tttgatttcg aatttgagct tctcaaattt
    26161 ttctctcaat ttcttagcac ttctaatatt tccaaaccaa aattcatttg taggtagcca
    26221 attgatcaca tactcaatcg cttctataga cgctttatct ctttcttcca tcaacctgat
    26281 tgtgtctgcc catttttcga tatctacttt gttcatttct tttggaaaat cttcagttaa
    26341 attactttgc aattttttag caaggcgtaa gtgttcgtca gaatacttac ctttcttttc
    26401 ttctttatct atatctatat ctttctctat ctctatctct aactctggtg tagttttgtc
    26461 tggacatttg tccgacactt gtcctccagt tattaaattc cgttttgcct cttctatttt
    26521 ctttctgtat tctctttttc tatctgcttc agttgaggat tttccaatga aactttgtat
    26581 atcagacata taaattgctc cgttatctaa tacgtcaata agctgcaaat cacggaaaat
    26641 ttgtaccgct ttttctacga ctcctacaga atgtcttgta atagttgcga gcattgtaga
    26701 gttaaatgga atcctgtcat taaacatcaa cttaccttcg tgttttagac ttcttaaata
    26761 aagtttgaga agaatattag aataaatata gccatctggc atactttcta agagaaccat
    26821 ctcgtcacta tcgaaaaaat tctcttttag ttttaaatag tagtagcgtt tgttgtcaga
    26881 caatattttt taccctccta ttctaagttt cttaattgtt tcctggttta acttgatccc
    26941 tttgatttga tatttatttt tgaaattgat cacacctata ttgtgtttct ccgtgtgatg
    27001 aatcctgcag agtgctgcaa atgtgtactc tgaatgatca acttctttgc gctttcgtct
    27061 tcctagcgct ttgtcaaagt gatcgatgtc agctcctgtt ttgccacaga tgcagcagac
    27121 tctttttgtg atgcatttgt agaagtaata ttcttgattc gctggtaaaa tctcatagcc
    27181 ttctttgaaa ggaatatgat gttcaaagat gaaatctaag atgatatttg ctaagacatt
    27241 agcatcactc acagttgtat tcgattcgtc tttgaggctt attttgcgcc ctgtgacgcc
    27301 ttcaaaacgg aagtaaaaga attccttcca gaagtccgtt ggcatgcctg tatcgatgaa
    27361 aatatcgcct atcagcgcat agatgaagtt tcgttgctgc acagtaaatc gacgtggatc
    27421 aataaatcga acttcaataa tccgatcgcc atcatatccg tcatacatcg tctttagtcg
    27481 atcaatgttc acttcttcat tgatcgttgc acctatgtct tttcctttga actttttcag
    27541 aaccgctgaa tatgaatcga tcaatggttt aaacactcat atcacttctc ttttgtttct
    27601 tctctgtact gatcttcaat ccagttaacg cctcgtttta gaatgcccaa gtctctcttg
    27661 gtccatttac tgtcatcagc ggttatagaa gccgcatcag tcaatgcaac aattgcttca
    27721 tcaattgatt tttcgtactt gttagcaacc agttgtaaag catccaagaa tagctttttg
    27781 cttctttgag tagctggttc aagcatcgag acatcttctg gcatatcttc gccagcaaat
    27841 atatatagcc ctagcccaaa cattgctaga ttttttacaa gacagcgcat gatcgttttg
    27901 ttgatatcaa acatagttgc tgcttcaact cgcttttcga tttttccaac aatctctttt
    27961 ttcttcgttt cgttattcca ctgataatca ttgacttcgt aggtatatgg ctcatctttc
    28021 attgccttgt ttgcaccatc catgactggt aaccacatgt cacgctttac tccgttgact
    28081 gtgatactgg taaaaaccat atagcctgtt ttcttatcaa agacatacgg cagatatgtt
    28141 tctggatcat gatagatttc ataatctact gcctcacaca ctttgctaac ttctgcccaa
    28201 gcccatgccc acgaaagata agtgaggtta tttcgttttt cagtaacatc tttcacattt
    28261 attttgtata aggtattaaa aagcgtatta tcacttctat ttttcaaagg ttgttccttt
    28321 tcactcatca aattctgcct ccatttcagc aatgtatttc ttacctgatc cgtaataaga
    28381 gatatcaatc aagttatctc tgtcatactc ttctagcgca tcaatcaagc catcttcgat
    28441 gacatagata tattcagttt ttttggactt cctcgataaa tggataagat agacatgatc
    28501 ccaaatactc acaaaatttc ccaaatcgtc ttgatcacat gctagttctt catccgtcaa
    28561 aagattacgt ctgatttttc gattgcttgt ttccttgata ttcgatttgc cccaactagg
    28621 atcagtcaaa tattgatcta gagtggaaag ttcttttttc atgtggtaac atctccttag
    28681 atgtattttc tttgtgactc attgctttgg tcggctgagt cactttttta tttgttgcca
    28741 tgctttttgc ttatcaatat gttgttggct taggatgttt ggtttattgt gtctccacca
    28801 gcgattagca attattacgc ctatttttag cgcttcagct ctattcatcc tctaacaact
    28861 ccatttgctt aataattgtc atcgtcgctg tagaaggcat ccaattgtta ataaaatcga
    28921 taacatcatc gaactgtttt gccttgatac gatttctagc tactgctcca gtgattcgct
    28981 taattccgcc attcaagtct ttaaacaatt ctgcttttgc tttgctattt aaatgctgct
    29041 gattacaaat aactctaatt ttgttgcgaa ccatattaga aattgttcgg taatctggtt
    29101 cagctagaag ttgattgttc ttcaaatcgt ttaaatcaga ctcgatagcg tctactcttt
    29161 cattcgtttc ttcgtttgca gctagagcaa gtaatgccat ttctcgttta gttgctggaa
    29221 ttgatggcaa ttggtctttt aattcttttt ccatcttgtt gaaggcctca atatattgaa
    29281 gtttaaaact taaagctttc ttaccagtga agcccattgc taatagagag aagccgtctc
    29341 tattcatata aataattcgg tatgattgtt tattttgagg atgaacataa gtatcttccc
    29401 aaaataggtc tgcccaattt tcggcaaccc cctcttttag ttcatcaata gccgtcaaaa
    29461 catgtctgtg ctttttatcg aagctttctg caacttgtaa gctcgtagtc acagcttctt
    29521 tatttttcaa aatta
//
LOCUS       DAFLWZ010000028        29097 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000028 DAFLWZ010000000
VERSION     DAFLWZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.028"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1031)
                     /locus_tag="L1V38_001350"
     CDS             complement(<1..1031)
                     /locus_tag="L1V38_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315906.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="L1V38_001351"
     CDS             complement(1113..1802)
                     /locus_tag="L1V38_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1315907.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1V38_001352"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1V38_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBN1315908.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="L1V38_001353"
     CDS             complement(2329..2832)
                     /locus_tag="L1V38_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBN1315909.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1V38_001354"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1V38_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBN1315910.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1V38_001355"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1V38_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBN1315911.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1V38_001356"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1V38_001356"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBN1315912.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1V38_001357"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1V38_001357"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBN1315913.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="L1V38_001358"
     CDS             complement(6444..7463)
                     /locus_tag="L1V38_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1315914.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="L1V38_001359"
     CDS             complement(7636..8541)
                     /locus_tag="L1V38_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1315915.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1V38_001360"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1V38_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBN1315916.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1V38_001361"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1V38_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBN1315917.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1V38_001362"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1V38_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1315918.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="L1V38_001363"
     CDS             9754..10398
                     /locus_tag="L1V38_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1315919.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="L1V38_001364"
     CDS             complement(10454..10957)
                     /locus_tag="L1V38_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1315920.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="L1V38_001365"
     CDS             11554..12519
                     /locus_tag="L1V38_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1315921.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="L1V38_001366"
     CDS             complement(12618..13790)
                     /locus_tag="L1V38_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315922.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="L1V38_001367"
     CDS             complement(13777..14922)
                     /locus_tag="L1V38_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315923.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="L1V38_001368"
     CDS             complement(14936..15868)
                     /locus_tag="L1V38_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315924.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="L1V38_001369"
     CDS             15985..17064
                     /locus_tag="L1V38_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1315925.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="L1V38_001370"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="L1V38_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="L1V38_001371"
     CDS             complement(17789..18016)
                     /locus_tag="L1V38_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1315926.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="L1V38_001372"
     CDS             complement(18119..20707)
                     /locus_tag="L1V38_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBN1315927.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="L1V38_001373"
     CDS             complement(20727..21386)
                     /locus_tag="L1V38_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1315928.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1V38_001374"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1V38_001374"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBN1315929.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="L1V38_001375"
     CDS             complement(22159..23025)
                     /locus_tag="L1V38_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1315930.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="L1V38_001376"
     CDS             23134..23775
                     /locus_tag="L1V38_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBN1315931.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1V38_001377"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1V38_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBN1315932.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="L1V38_001378"
     CDS             complement(25216..26115)
                     /locus_tag="L1V38_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1315933.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="L1V38_001379"
     CDS             complement(26117..26914)
                     /locus_tag="L1V38_001379"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBN1315934.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="L1V38_001380"
     CDS             complement(26892..27596)
                     /locus_tag="L1V38_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBN1315935.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="L1V38_001381"
     CDS             27727..28302
                     /locus_tag="L1V38_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBN1315936.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="L1V38_001382"
     CDS             28420..29097
                     /locus_tag="L1V38_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1315937.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8560 a         6167 c         5232 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaa
//
LOCUS       DAFLWZ010000029        29096 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000029 DAFLWZ010000000
VERSION     DAFLWZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.029"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            278..1063
                     /locus_tag="L1V38_001383"
     CDS             278..1063
                     /locus_tag="L1V38_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1315938.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="L1V38_001384"
     CDS             1076..1927
                     /locus_tag="L1V38_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBN1315939.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="L1V38_001385"
     CDS             complement(2051..2503)
                     /locus_tag="L1V38_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315940.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="L1V38_001386"
     CDS             complement(2968..3336)
                     /locus_tag="L1V38_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBN1315941.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="L1V38_001387"
     CDS             3486..3968
                     /locus_tag="L1V38_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBN1315942.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="L1V38_001388"
     CDS             4005..5015
                     /locus_tag="L1V38_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBN1315943.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="L1V38_001389"
     CDS             complement(5130..5843)
                     /locus_tag="L1V38_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315944.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6033..6623)
                     /locus_tag="L1V38_001390"
     CDS             complement(6033..6623)
                     /locus_tag="L1V38_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBN1315945.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7107..7334
                     /locus_tag="L1V38_001391"
     CDS             7107..7334
                     /locus_tag="L1V38_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBN1315946.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /locus_tag="L1V38_001392"
     CDS             7350..8516
                     /locus_tag="L1V38_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBN1315947.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="L1V38_001393"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="L1V38_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBN1315948.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="L1V38_001394"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="L1V38_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBN1315949.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="L1V38_001395"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="L1V38_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBN1315950.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1V38_001396"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1V38_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBN1315951.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14394)
                     /locus_tag="L1V38_001397"
     CDS             complement(13729..14394)
                     /locus_tag="L1V38_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315952.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14370..14543
                     /locus_tag="L1V38_001398"
     CDS             14370..14543
                     /locus_tag="L1V38_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315953.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="L1V38_001399"
     CDS             complement(14588..15325)
                     /locus_tag="L1V38_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1315954.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="L1V38_001400"
     CDS             complement(15327..16829)
                     /locus_tag="L1V38_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBN1315955.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="L1V38_001401"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="L1V38_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBN1315956.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="L1V38_001402"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="L1V38_001402"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBN1315957.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22171..23436
                     /locus_tag="L1V38_001403"
     CDS             22171..23436
                     /locus_tag="L1V38_001403"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBN1315958.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23440..24171
                     /locus_tag="L1V38_001404"
     CDS             23440..24171
                     /locus_tag="L1V38_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBN1315959.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24306..25190
                     /gene="rapZ"
                     /locus_tag="L1V38_001405"
     CDS             24306..25190
                     /gene="rapZ"
                     /locus_tag="L1V38_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBN1315960.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25187..26185
                     /locus_tag="L1V38_001406"
     CDS             25187..26185
                     /locus_tag="L1V38_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBN1315961.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26219..27154
                     /gene="whiA"
                     /locus_tag="L1V38_001407"
     CDS             26219..27154
                     /gene="whiA"
                     /locus_tag="L1V38_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBN1315962.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27697..28347
                     /locus_tag="L1V38_001408"
     CDS             27697..28347
                     /locus_tag="L1V38_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315963.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28534..>29096
                     /locus_tag="L1V38_001409"
     CDS             28534..>29096
                     /locus_tag="L1V38_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBN1315964.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9564 a         4897 c         6177 g         8458 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgagctta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat gaatttttgc
    21961 ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct acactgattg
    22021 gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag caatcggagg
    22081 actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt tggaaaagaa
    22141 aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa tgaagaattt
    22201 atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc ttttaatgaa
    22261 gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac ccgctacagt
    22321 aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt tatcgagacg
    22381 atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct tttgattgct
    22441 tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc agaatatttt
    22501 atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt aagcttttat
    22561 gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag agaagaaatg
    22621 ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc tttgaaacct
    22681 gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc ttttatttta
    22741 gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg ttataaaagt
    22801 gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt gctaaatgcg
    22861 tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact attagaagat
    22921 cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa cgaaaaaatc
    22981 tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc caatttcgat
    23041 atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt gagacaaggt
    23101 cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt cacagaagat
    23161 cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc agataaagca
    23221 agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga aaatgaagac
    23281 aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt attttatgaa
    23341 aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa ctatattcca
    23401 agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt tttcagtatt
    23461 ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa ccaccgaacg
    23521 aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc aacagttcct
    23581 gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt tctgctggat
    23641 gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg taacaccgca
    23701 cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca tatgccaaga
    23761 gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat tctaggaaca
    23821 gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg tttcgaaaca
    23881 gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca tgagatcaag
    23941 gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc ggtagagcgc
    24001 ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca tgaatttgct
    24061 gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg aacgatcgaa
    24121 cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta aaaaaattgg
    24181 atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa gaaaaagaaa
    24241 actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga gaggggttcg
    24301 taaatatgac agataatttg caattagtca tcataacagg tatgagtggt gcagggaaaa
    24361 cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat atgccgcctc
    24421 gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca aaaatggctt
    24481 taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg ctgatcgaaa
    24541 tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca gacgaagaac
    24601 tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac ggtttgatca
    24661 ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa gcttccgtga
    24721 tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat gagtcattca
    24781 aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt aaatacgggt
    24841 tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct cattatatcc
    24901 cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg atgtcctttg
    24961 atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta ttgcctggat
    25021 acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc ggtcaacacc
    25081 gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat aaagtcaatg
    25141 tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga aaatgaaaac
    25201 ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc tgccagttat
    25261 cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg ttgcagatga
    25321 tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg gtgacttgag
    25381 aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt tccaataccg
    25441 tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga tcattgccgc
    25501 agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa aaatgatgca
    25561 tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg ctgtttttaa
    25621 agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa ccattgaccg
    25681 tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa aagtcgtttc
    25741 agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca ccagtatcct
    25801 tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg ctgaaaccgt
    25861 ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag atgccgatca
    25921 tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat tggtcaatac
    25981 ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc tagtacaagt
    26041 cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca ccgacttttt
    26101 agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag aattgttccg
    26161 tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg agaataggat
    26221 gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc gagaacatgc
    26281 gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg tgaaccagca
    26341 gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct attctctttt
    26401 gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga aattaaaaaa
    26461 gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga tggatcttga
    26521 tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg gaaattcgca
    26581 aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca ataatccgga
    26641 aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc aagacatttg
    26701 cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca atggctatat
    26761 ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg gtgcaaccaa
    26821 ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt cggtcaatcg
    26881 tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt ctaaacaaat
    26941 cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg aaaaacttca
    27001 ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat taggggaaat
    27061 gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca aaataaatga
    27121 atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg atacatgaag
    27181 caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct tccgtcaaac
    27241 tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt tttttaatac
    27301 aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac ataaactttt
    27361 gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac tggagattaa
    27421 ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta cttctggtca
    27481 agattctcgt ggttggtgga taaggatggt tgataagttc attggattag ctagtcgaaa
    27541 acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt tattcagtga
    27601 taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta tacctgaact
    27661 tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg agggcaaaaa
    27721 atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat
    27781 atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata
    27841 acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact
    27901 acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct tgaatatgaa
    27961 atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat aggaagtttt
    28021 agagggaatg tgacaactca acctagacga agttggagta taaaactttt aaataatagt
    28081 ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga tgtaacaatc
    28141 actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa gccacagctc
    28201 acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt agaagaagct
    28261 cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc gccaccgata
    28321 agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa atttatgtgc
    28381 gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg aagcatggga
    28441 tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg gtgatgctat
    28501 aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt atggatattc
    28561 atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc aggttattat
    28621 ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat ttttaattgg
    28681 ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa tagattaata
    28741 ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc ttggataggt
    28801 ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag tatttatagt
    28861 gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt tcttttgtgc
    28921 ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg tgtaaacaat
    28981 ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc aaggttgttg
    29041 ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt tataga
//
LOCUS       DAFLWZ010000030        27890 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000030 DAFLWZ010000000
VERSION     DAFLWZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.030"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(424..1368)
                     /locus_tag="L1V38_001410"
     CDS             complement(424..1368)
                     /locus_tag="L1V38_001410"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1315965.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1664..2608)
                     /locus_tag="L1V38_001411"
     CDS             complement(1664..2608)
                     /locus_tag="L1V38_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315966.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2829..4043
                     /locus_tag="L1V38_001412"
     CDS             2829..4043
                     /locus_tag="L1V38_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1315967.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4065..6080
                     /locus_tag="L1V38_001413"
     CDS             4065..6080
                     /locus_tag="L1V38_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBN1315968.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6163..7536)
                     /locus_tag="L1V38_001414"
     CDS             complement(6163..7536)
                     /locus_tag="L1V38_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1315969.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7562..7846)
                     /locus_tag="L1V38_001415"
     CDS             complement(7562..7846)
                     /locus_tag="L1V38_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1315970.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7848..9863)
                     /locus_tag="L1V38_001416"
     CDS             complement(7848..9863)
                     /locus_tag="L1V38_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1315971.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10042..10347)
                     /locus_tag="L1V38_001417"
     CDS             complement(10042..10347)
                     /locus_tag="L1V38_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBN1315972.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10436..11467)
                     /locus_tag="L1V38_001418"
     CDS             complement(10436..11467)
                     /locus_tag="L1V38_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1315973.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11674..12549
                     /locus_tag="L1V38_001419"
     CDS             11674..12549
                     /locus_tag="L1V38_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1315974.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12701..13543)
                     /locus_tag="L1V38_001420"
     CDS             complement(12701..13543)
                     /locus_tag="L1V38_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1315975.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13635..15512)
                     /locus_tag="L1V38_001421"
     CDS             complement(13635..15512)
                     /locus_tag="L1V38_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1315976.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15509..16930)
                     /locus_tag="L1V38_001422"
     CDS             complement(15509..16930)
                     /locus_tag="L1V38_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1315977.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16933..20322)
                     /locus_tag="L1V38_001423"
     CDS             complement(16933..20322)
                     /locus_tag="L1V38_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1315978.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20579..21970
                     /locus_tag="L1V38_001424"
     CDS             20579..21970
                     /locus_tag="L1V38_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1315979.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22043..22690)
                     /locus_tag="L1V38_001425"
     CDS             complement(22043..22690)
                     /locus_tag="L1V38_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1315980.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22698..23384)
                     /locus_tag="L1V38_001426"
     CDS             complement(22698..23384)
                     /locus_tag="L1V38_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1315981.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23390..24463)
                     /locus_tag="L1V38_001427"
     CDS             complement(23390..24463)
                     /locus_tag="L1V38_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1315982.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24685..25359
                     /locus_tag="L1V38_001428"
     CDS             24685..25359
                     /locus_tag="L1V38_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1315983.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25364..26704
                     /locus_tag="L1V38_001429"
     CDS             25364..26704
                     /locus_tag="L1V38_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1315984.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26853..27839)
                     /locus_tag="L1V38_001430"
     CDS             complement(26853..27839)
                     /locus_tag="L1V38_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBN1315985.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8137 a         5268 c         5052 g         9433 t
ORIGIN      
        1 aaaaatgata aacctctctc gaacggtttt ttatcaaaaa tcgtcatttt tccatcaaaa
       61 tctgcttatg caaaattata aaaaaatttt gcagtttttc ttactttttt tgtcgtttaa
      121 ttgaatgata aaaaccagtt tctttattca gttaatcaaa tatgaacgaa ttagatatga
      181 atcattgtat ttgccgttgc ggaaggattt tttaattaac cacagataaa cattgataac
      241 gattcgctta ttgtaatcaa cagattaaat ttcatatgtt catatgtacg gatacatttt
      301 cggaccgatt aattttaacc attctattta tttgcttacc tattagatat caataaaaaa
      361 ctgcttaaca gctatttcag ctgttaagca gttttaggat ttttagttca tattcattgt
      421 ttcttataat acagtgttca atacttctct taaagcactt gttgatttgc tgaacattgc
      481 tttttcttct tcgttgattg ataattcaac aacttcacga acaccatttt cgtcaacgat
      541 tgatggcaca cctgtaaaga tatctttttc gtcgtattca ccagttaaat aagcagatac
      601 aggcaataca gcttgttcgt tattcaagat agcttttacg atacgtgcag tactcatacc
      661 aataccatag taagttgctt ttttacgatc aatgatctca taagcagcat tacggacttt
      721 atcagcaatc acatctaatt catcttgggc aatacgatgg tctttttcta caatttcaaa
      781 cactggttta ccaccgacag ttgtatgtga ccatgcagca acttctgaat caccatgttc
      841 acctaagata tagccgtgga cgctgcgtgg gtcaactttt aatttcaatg cgatttcttt
      901 acggaaacga gttgtatcca atgttgttcc agtaccgata acacgtgatg ttggcagacc
      961 agattcgttc caagcgatat atgtcaaaat atctactggg tttgaagcaa caacgataat
     1021 accgtcgaat cctgatccca tgatttcttt tacgatttgg cgcatgattg acgcatttgt
     1081 tttaactaaa tctaaacgag attgaccagg tttttggttg ataccagctg tgataacaac
     1141 gatatcagca tctttacatt cttcatagcc acctgaccat acagccacat tttcatcgcc
     1201 ccaagccata ccatctaaaa ggtccaatgc ttccccttct gctttttctt gattcacatc
     1261 gatcaatact aattcattag agattccttg gttgatcatt gcataagcga tacttgttcc
     1321 aacaaaacct gtaccgacga ttactacttt acgacttgtt tttttcatga ataaacagct
     1381 ccttttcata actatttgtt actttcatga aaagtatagt cttgtttatt cattttatca
     1441 acatgttaat tataatagtt gttattataa tttttgatgg aaacgaattc ctgaatacgc
     1501 ataacagata aatgacaaat gtttacacct atatcccctg ataatacaac caaaagttta
     1561 gaactgaaaa taaatccaaa aaaattcgct gcaacgatat aataagacag caatcgcacc
     1621 taaaacaatt ttccttcata tgctttagtg aaagattttc ttcttaatgt ttatttctcc
     1681 attcattggg agtacatgtt gaatacttct tgaataattt gaataaagaa gtcgtttgtt
     1741 tatatccgat acgattagcg atttcttcca acgaaaaact cgtttcttga atcagttcca
     1801 acgcaaagtc gaattttttc tttagaacca gttcttgaaa ggaagcatca aaatacattt
     1861 tcaatttatt actaagatag accggattgt agccaaaatg agctgctgtt tcttttaacg
     1921 tacaagaagt aaaatgctta tcgatataat ctaatactct aagcatctca ttttctgcgc
     1981 atccatctgc tgatgaaaag ctttgttgtt ctaataaatg agtcaattcg atcagtaata
     2041 gtgatgtata gagatttaac gaacggatct tatgactgta tgtatcaaaa taaatcaaca
     2101 gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc gccgcgaaaa tgaatgaatt
     2161 gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa agaagaaagt agattatttg
     2221 tgcttgccaa atgattcaat atctctgtag ataaggtttc ttcttttaat aagatgttga
     2281 ttaaaatatc ctcttgccct gtgtattcga ttctttgagt agcttcttta tcaatgatca
     2341 ccacgtcact ttcttccatc tctatccttt ctccattaat aatttgtaaa catgtaccgc
     2401 tatacatata attgatttca acaaaatcat gtgtatgctc gggaacttcc gcatatcgac
     2461 ggtgtttact gatatgaata tttccctgtt gaaatagatc ccctcggtgg atttttggcg
     2521 gtgtctgaag atggtaagct aagtttaaat cattgatatt cattccttgt tcacgctgca
     2581 gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta attcagctag ttccaattga
     2641 ctccctcctt tttgtaagcg gtttctttcg cttattagtt cacgctgtac tgctattata
     2701 tgcaaagcta tttttggttt cataaagact ttctatggtt gggacatgaa cttcctgtga
     2761 ttccgctatt gagagaataa ccacttcata ctatattttt gataagcgct tacaaaaatg
     2821 aaaggaacat gcttatgaat aaaaagatga tgaaattttc tctgctgtca gtctctctta
     2881 ttttgacttc tgctggtgca gtcacgtctg caattcccag tatgtcagct acttatgcca
     2941 cgcgttcttt atctgctgtt gaattattaa cgactgctcc ctcttttatg gtcactattt
     3001 ttgttttgat tagtagtttt attgctagga aaatcggaca aaaacaaact gtgatcatcg
     3061 gattagtgat tgcatcgatt tgtggtatcc tccccctctt ctcacaaagt tacagtattg
     3121 tcttagcttc aagagctgga ctaggtattg gctttggatt gatcaattct ttggcagtca
     3181 gcatgattgc tgccttttat cacggagatg aacgagcctc tatgattggt tttcaaagtg
     3241 catttcaagg atttggtgca gctttaatga catttgttgc aggacagcta gtacagttcg
     3301 gttggcaata taccttttta gtctacgcca tcagcttacc tattcttgtc ttgtttgttt
     3361 tgtttgttcc tacacctgaa acaactgaac ttcaatcgca tggcacagcc ccaacaagac
     3421 aagtaatcaa aacgaatcct aaaatgatta gttatggtat ttttctcttg ctggtcatcg
     3481 tggtatataa tgctgtatcg attaaattag ccacagtcct gacgacttat tctctaggaa
     3541 acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt ggcaagtatg gctgccggag
     3601 tttgttttgg ctggcttcag acaaaagcac atcgctatat gcttacactt tctttactac
     3661 tgatgggaat cggctttgta ttgattgcca ctgtgataaa cctgtatgtg attgggtttg
     3721 gtgcgatcct aacaggaatt tctttttcgt tattcattcc ttacttattc aaccaagtaa
     3781 gtatccaagc gcccaagtac gcggagagtt tcaatacttc aatcttattg gttggcgcta
     3841 atttaggtac tttcattgca ccatatggtt tgctctttct ctcttttgct tctcttggga
     3901 gtaaaacact tgctgttttc gtcaatggca gtatcttgct gttgattagc gcgcttatta
     3961 gccttctagt agtacacagg acgaatagaa agacagtgat aagagtagat gaagaaataa
     4021 aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg taaaatgaca aatgaaaaac
     4081 ataaagatag atggctttgg tatcctggag actttgagat ccgccatgga ctgctacaaa
     4141 atttccaacg ggaagaacga ggttttgact ggccagcgta ctggtacatg gatgattgcc
     4201 atcggaacgt caagtttaag agatattact ttcttgatca accttccatg tttaaagtga
     4261 cgatccaagg agttgggtat gtagaaatta atggacaaaa acatccatgt ggaaaatggc
     4321 tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt aggacataca tcagggctac
     4381 cagcgatgtt tatcgaggga gacgaagtaa aatcagatat tggctggaca gcaagtaatt
     4441 ttattgaaga atatccagct ggctggagtc cgctttatgt cgatatcgca aaagatccaa
     4501 atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac tgaaacggag attggcggag
     4561 gaatcttatt cgattttggg cgagcagtga atggctgtgt agaactaata tctctggatg
     4621 accatatcga atctatcact ctatgttatg gagagtccga tgtagaagct atggatatcg
     4681 attattgcta ctataagcaa ataggaatga caagaaaaat gaaagctcgt aaacgcgctt
     4741 ttcgctattt gtttatacca gaggtttcta ctggaatggt tcaacttcaa gtttttcatg
     4801 aatttttatc tctttcgaaa caagctgctt tttcaagcga ttcttcttta ctgaatcaga
     4861 tctggtcagt atcagaagaa gccttcaagt tatgtagtga tttgtttttt atcgacggta
     4921 tcaaacgaga tcgctggatt tggtctggag atgcgtatca atcattcatg atcaatcaat
     4981 atcttttttt tgacgaggaa atcaataaac gaacgatatt agcattaaga ggacaaaatg
     5041 aaatcaagca gcatatgaat actatcgttg actattcgat cttgtggttg attggtatcg
     5101 aaaaccacta tatgatgacg aaagactatg aatttttacg catcgtctac cctaagatgc
     5161 aatcattaat gagatacttg atggagcaaa cgaatgaatt agggtttatt tatgggagag
     5221 caaaagattg gatatttatt gattggtctg aaatggataa agaaggaacg cttgctgcag
     5281 aacaagtctt attactgaaa gcctatcatt ccatgatcac ttgcggagat atcttagctg
     5341 aaacatatgg agagaacgaa aattatcata ctcatctcta tcaagaaaaa tatcaactat
     5401 tgaaacaaaa cctatttgac tacttttggg atgaagaact tggcgctttt atcgattgct
     5461 atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat tttcgctgtt ttattcgatt
     5521 ttgctaacaa agaccaacag caatcgatct taaagaatgt cttattgaat gacactatca
     5581 cacagattac tactccatat ttcaaattct atgaacaaga tgctttatgc aaactcggac
     5641 agacgaatat cgtctaccaa acgattcttg attattgggg agggatgtta tctcatgatg
     5701 cggtaacttt ctgggaagaa tacgacccta ctcaaacagg aaatgaaaag tacagtatgt
     5761 atggagatcc ttatggaaaa agcttatgcc atgcatgggg agcaagccca atctatcttt
     5821 taggacgcta ttttatcggt ttgtatccaa caaagccagg ttatgaagaa tttatgatac
     5881 aacctaatct agattcattt gaaacactga attgtacgct acctatcaaa gatggaaaga
     5941 tttcgcttga aaaaacaaaa gataagatcg tgattacttc tgatagaaca ggcggaacag
     6001 tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca gccacttgtc ttaacaagct
     6061 attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac atatcagaag actttaaatc
     6121 ttcttctgat attgtccaag caatttttat tttgaagttt gcttaattct gttctttaga
     6181 aacaatgttt gttctttttc cggcaaaaag aaagctagat aatacgacaa gtaaaaagaa
     6241 agcgatgatt ccaactgtca aggctatttg accgtattct cctagtttcc caagtacaag
     6301 tcctggtact agataatcag tatcggcaaa tgtagaagaa gcgattttaa gatctcctaa
     6361 tactggaagg ataaataatg gcagccaact aatcaataag ctattgaaag cagaacctaa
     6421 taccgcccct cttctaccgc cagtcgagtt gccgaagaca ccagaagcag ctccgcagaa
     6481 gaaatgtcct actaccccag gaatgataac tgtagtttgc aagcctatca tagcaaacat
     6541 ggatagtgtt cctacaaaga agctaacaaa aaagccaatt aatacagcat taggtgcata
     6601 tggaaaaacg ataggaacat ctaatgctgg tttagaatcg ggtacgagtt ttttagcaat
     6661 cccttggaat gctggaacga tttctgccaa caccattcga accccttgaa ggacgataac
     6721 aaacccagct gtgaatgttc cagcttggat cagtgcaaag attacagcgt tgtctccatt
     6781 gcttagttct ctttcaacaa atccaggacc agctaacaaa gcaagtgcga catatacgat
     6841 cgacatcaag agcatgatcg atacagtaga atctcgcaaa aagctgaaac ttttaggaat
     6901 ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac tttccgatcc atccactaga
     6961 agcataaccg atatttccgg tatgccctaa cgcaacttga ttgtttccag tgatgttctt
     7021 cataaacggt tgacaaagag caggcgtaat agttaatagt gttccttcga agaccccgcc
     7081 taataagatc atccacaaat ttgcagtaaa ccccgcgctt actaaaatga ctgctgttag
     7141 acaagaaaca taaagcattg cttgacctgt aagaaaaatg aatttatatc ttgtgaatct
     7201 agcaagtaaa atattcacga tcatccctac tagcatgatc aaagcagtag gtgtaccgta
     7261 ttgttgcaaa gcaatcgcca ctactgcttc attgctagga actactcctt gagtatgcag
     7321 agctgtttgg aacatcgaag caaaaggggt tagtgaatta ctgattaaac cagcaccgcc
     7381 gatcagtact aggaatccga caaatgtttt gatagttcct tggatcactt ctgaaaattt
     7441 cttcttctga agaacgagac caagcagtgc aatcaaagaa acgaggatgg agggctgact
     7501 gacgattgac acaaacaaat tcaacaattt atccattgat agttcctccc ttgaatcatt
     7561 tttattcttt tgacaagatc ttcgttactt tttcttttac ttcttcgctg tcaatgatcg
     7621 attgcaaagg tacgagcttt tcatcaggta tagaagttag cgtatctttc aaagaatgct
     7681 caatgaagaa ataatcagcc atatcgctag atacacttcc aacatccgta tgacttactt
     7741 caaactcgtc cacatctgct ccaagatctg caagtgcttg tttgatgttc atctctacca
     7801 taaaacttgt tcctaatcca ctttgacata ctgcaaaaat tttcatatca ttcgtctcct
     7861 tttcttatga tcgctaatat ttcttctttt gttgatgcgt gtaataaatc ttgaagattt
     7921 tgtttattag aaagtagctt tgttaaattt gccaaagccc gaagatgtgc ctcattatcg
     7981 atagcagcta aacagatgaa caaactaatg ggatgggctg gattatcaag cagatccaca
     8041 ggttgttgaa gtttcagcaa agacatccct acttcgttta cgccatcttc tggacgagca
     8101 tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac catactgctc cacgcgctcg
     8161 atcatagctt tgatataact ttcttctatt ttattttctg ataatagcgg ctgtgcggca
     8221 aatgtgattg cttcttgcca gttttttggt tgatccgata attggatcat ttcttctgtt
     8281 aataattcag atagcatagg acgttgatcc tccttctttt ctaaaagttt gttcatttta
     8341 cgatttaata cttgatagag cttttcttcg tctacgcctt cttttaattc gatataaggc
     8401 agtagcgccg acaacaattc ttgggcagaa ggcattgaaa atcctggtat cagccaatct
     8461 ctttgtactt gattgatcag ctgatttttt tccaagtcag tcatgattgg atgcagaaca
     8521 tagagagact ttttcttatc agtaagtgtg agaggtacag tagaaaaaat aatatcgtaa
     8581 gaagtttcgt caacctcgtg taagcggtca gctgaattag tctctgtaaa aaagatcatc
     8641 gggaataatt gctgaagttc actttttaag atcaatgaag agctaatgcc acttggacag
     8701 acgatcacgg ctcttatttt tctatttctt tcttctgcgt ccgcttttct gatctctccg
     8761 ccaaatagta tagtgaaaaa accaatctct tcttcaggga tgctcttccc tattcgtctt
     8821 tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg aagcatattg atgcttaatt
     8881 tgatcgatca tcacattagg taaataaaaa gaataggaaa tacgaaaata ggcagggacc
     8941 aagtgataaa agacattcat caataattca cgaaacgaag caaattctac ggccatcagg
     9001 aattccatgc gatggatgac ttctgaagaa cattccagca aaaaatcaag tgcaggctcc
     9061 tggacatctc cttcaacgat cgatgctaag caaagagaga aaaatataat ctccgaattt
     9121 tgatgttcgg aatagccaag gccagtcaat acttgtcgac taatgtcagt gactgcaaga
     9181 gaagccaaca gttcagcatc ttttaccagt tccatggatg tttttccaat tcgaatggtt
     9241 gtcaaactca aataataagc taattcatcc attcgatttg gtgcgaatcg aagatctgat
     9301 agtgaaatcg ttttatctag caaatctcta actttggcgt aataatcaat ggaaagggtt
     9361 gcggttaaat acgtgagccc aaatcttcca gcaagtgact gcatcaaacg agcagtgcga
     9421 ttttttgctt ctcttcttaa tattgcttct gaccctagca gcctaaaacc agttttccta
     9481 gtatacgaca gctgacaatc ttccacttct aattcatttc ttatcttttt gatatctgac
     9541 aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat gaaaaacaga aacagacgtt
     9601 gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct cttgttcggt atacacagct
     9661 tcaaatcgag taatatccaa aaatttttct gcccagtcga ttgctcggaa tttctttata
     9721 cggatacggg tatcatccac atattcggca aaaggagtta attgtttgat cgcctcgctt
     9781 gtatttactt cgatgatctc tgctgctttt tctagactga tttctcttgg tgttttcagg
     9841 agataactaa ttttgtagtt cacagcgctg ttcacctcct acttatattc tagtatggta
     9901 gcgcttttaa atcgaggggt gtttggtaca acttacagtt ggattttttt tacgactgta
     9961 ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg tgaccaaatg tctcctgctt
    10021 ttatgaattg atttcgtccg atcaatgatg atcatgttta ttttttgagg tcagttcttc
    10081 aaatttttct ttgacatctt caaccgcttt ttcgatatct ttttcaaagt gattgggctc
    10141 attaggcttt gtttcctctt ctacagaatt tgaaccagat aaagctgttt ctttattttc
    10201 tgtttcacca gagtttgtgc cagctaatga ttcttctttg tcttctgttt caccagaatt
    10261 agttcctgct aaagccactt cttcttctgt tttaggggcc attgaacctc ttaatcgttt
    10321 gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct agtagttcta tactttttca
    10381 tcgtacaata agacagttta tgcgtcaaaa aacaaacccg attcttacaa atatgtcata
    10441 tttttccttc tgattcttga atgcttttga ttccttcttc caaaattttc atttgtaaga
    10501 ttgtttcttc atctttgatg actttttctg cgccattaac taatgtctcg taaatccctt
    10561 cgtagacacg gctgtaatca ccaacctcgg aaattacttt ttcttcatga taactccctt
    10621 gttcatctat ataggtcaat acaccataat gttcgggcaa atcgatacca aagtcttcat
    10681 gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg atcttttgtt tgtttcacga
    10741 acatcccttt ttttccgtaa acgacgaaac ttggacgttc tttgatgcgg aaataactgg
    10801 attttatcga aattttcata tttccataga aaaaatccag atcgaagtaa tcattcattc
    10861 gtcctttccc taaaagttga cgtacatcat agctgatatc atctggttcg ccgaaataag
    10921 aaagaacttg atctactgta tgacaagcat gtccatataa atagctgttc gcagtagaaa
    10981 attcatgcgt attttctggt acttccggtc tgaaataatc ataatgcatt tctacttcta
    11041 aaatatcccc taattttccg ctttcgatta ctttttggac tgtcaagaag tcagaatcga
    11101 accgtctgtt ttggtaacat tggataaata gacctttttc ttttgctaat gcaaataact
    11161 cttctgcttc ctttgacgtt tctgcaaaag gtttctctac tagtacattc ttaccatgtt
    11221 cgagtgccat ttttccatat tcataatgaa attgactagg tgtagtgatg acaactaatt
    11281 ggatctcagg atcatcccaa agatcagaca gctgatcagt atattcgatg tcttcgaatg
    11341 ttttccacac tggttcagat ggggaaaaaa tttttttgat attgattttg ttcgtaagtt
    11401 ttcttgaaaa aggcaaatga tagcgatttg tactctttcc attgccaaga taagcgattg
    11461 taagcatgag tggtgcctcc ttttattgat gttttcagta tatcctagaa aagcgcagaa
    11521 agtatttata atagctattc tggtaaaaaa gttcagaaaa acacttgtta tcattcggtt
    11581 tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa gatagtagcg gaaccaagtg
    11641 tttatcagta agatagaatt tggaggtcag atcatgctta ttgaagaaaa actaacaaaa
    11701 caagagttgt ttaccacgac agagaaacgg attgtcgatt acatccgtag gaatatcgaa
    11761 gctgcagtct acatgacgat tgaagaatta gcaaaagcta cgtatacttc ccattcagct
    11821 atcattcgtt tatgcaaaaa aatgggattc agcggattta aagaattccg tttcgagctg
    11881 gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa cgattgatcc taattttcct
    11941 ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa tggcggattt atcgatccag
    12001 tcaataaaaa aagcacaatt gcagattgaa catgaagatt tagatcaaat cggtaaagta
    12061 ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg attctcaaat cacggcaagg
    12121 aaattccaga ataaaatggt caagttgaat aagtttttga tcatggctga agaatacagt
    12181 gattcttctt ggaatgcagc caatttgact agcgaggatt gcgccatttt tattagctac
    12241 agcggtcgca tccatcatta tgaacgaata atgacctatt tgaagcatgt agaggcccct
    12301 accttgctga ttaccggaaa tcagcattca gaaatggcca aacaggctga tatgtgtctt
    12361 gttatatcgc aggaggaata tgattttgct aaagtagcga ctttctcctc tcaaattgcc
    12421 ttcgattacg tattaaatac gttattctca gtgatatatt ctcaaaattt tgaagagaat
    12481 atccgcaact tgaaaaacaa acaagaattg atgcaaaaag gccttcttaa agaatatcgg
    12541 aaaacttaag aaaagatcct catttagtaa taagaaagat agtgtttgat aggctctctt
    12601 tgatatcatc ataaaaacag gctgaagttt tctttttcaa acctcagcct gtttgtttac
    12661 ggaacgattc gaatagatat attatagaaa tgaggaatag ctaacttctg tttcttattt
    12721 tgaacgattg acgaaaaaga tatataagaa ggaggaaaat cagtatacat gcagctaaca
    12781 atccatacag gaaaaatcgt ttgttctcgg atactttctg tacttctttt tgaacttctt
    12841 ttgcatgata aggaacccgg tgccctctga caagtaagcg atgactgttg accatataag
    12901 gtgtacaagt taggagtgtc acgaaatcct gccctttttc gattctcaga tcttttgtat
    12961 cagtcggttc taccgtcttg atctgatcga cttgataagc gagtgtccgt ccattgattt
    13021 cgatatagaa agaatcacct aaagtcagtt tcggtaagtc tgtgaacaac tttgcttgag
    13081 gcagtcctcg atggctggaa ataacggcat gtgtattttc tccccccgta ggataagacg
    13141 ttccttccaa taatgaggca cctttttcta gcagcacagt attcgtttca tcaaaaattg
    13201 gcaaatggac attgatctca gggatcgtca aaataccgat cgtatgtttc tcaaaatagg
    13261 ttctatcctt tttcgcaggt tcttttttct tagtaaaggg atctgcacct ggatttccac
    13321 cttcttttgc taattgctgg tttttctttg tcatgttttc ttggatttta gccatgactt
    13381 cttcattttc tttgaccgct tgttgctgat aatgagagat gatctgctga tccagataat
    13441 tattcagcgc gtcgctaaca aatggataag ctagtatccc tattcctgag agaagcaaga
    13501 aaagcatcag cagatctaga agtttccttt tctttggttt catttgtgtt ctccttgtga
    13561 tgactgtttg ataataaaag aaaaaggagc atttgcgtaa tccgctgctc ctttttccaa
    13621 ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag caaagtacag tccagcaatc
    13681 agtagaagga ctactcctgc accgatatac acatagattc ccttaccgcc tgttgaagga
    13741 agtgtacctt tgtgtttatt tggtattttt tcaggagaaa tcaactgtcc tgctgttaca
    13801 taagattgtt catcgatagt aaatgctaca cggtttgtta atggaacata tttttctggc
    13861 gctttcgttt cttccagata gtacgtgcca tattttagac ctgtcacatc gattaaaccg
    13921 ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg atacccagct gacggctttt
    13981 gtggatgggt cgatcgataa atatttcgct gtgtcactat cttgatcacg aacgacgaat
    14041 tctgctccag caagtgtttg gtctgatgta acgtcaccat ctactttaac aaatcgtttg
    14101 cccccagtaa cgacatcgac tgacggtggt gtttgatcat ttgtatgccc gttatcgaca
    14161 tttgcttggt tagaaaatcc tttggttgga tctgcttttt cgttcaaatg catatagtaa
    14221 acgaatttca atgtaccgcc aggagttaat gaaggaatat aattcggatc aactgaaacc
    14281 gtgaatccgt ctgtttgctc agtgacagaa taatttactg ggtcgatttc tttatttcca
    14341 tcatataagg cataagcata cgttcctgaa gaatcattat caaatgttaa agcagcgtca
    14401 tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg ttccttcttt atcagcgata
    14461 cctaatggga tattgacaga aatctcatat tgaatttttt caccgattgc gacatctttt
    14521 ccattcaatt gaggtgttgt tttatcaact ttagacgtat catttttgat ggtcttttct
    14581 actggtgttt ggctatttgc caggatctca aaaggcgtga ttgtttgctt ttcaatcatt
    14641 tccgcattat caggagcttt tacttcttct aaattatatt ttccaacttc taaatgatta
    14701 acgatcaact ggcctttttc aatagatgcc tcggcaaagt cattgttgcc gatgtcataa
    14761 gaatgaccag taatgaaatg tttggctttg gtttgatcag ttgtccaagt gtacaatcca
    14821 tctgtgacac tttggatgta ttttttgacg cttggtgttc cttcttcttt agaaataata
    14881 aattctgctc catttagtgc ttcgttttcg gcagtaccga tttttgtaac tttcaacgtt
    14941 ccatcattac cgactgtatt tttagggtag agatggatag tatctagttc ttctgtcccg
    15001 tatttataag agccatctgc ttgtttgatc atctcatata cagggaaagc taaaaccatg
    15061 tttgcggcag ctgacactcc gtcttttggt tcttctttga tcgtgtagac tgcatctttc
    15121 ccattttgtt ttttaggtaa agataaagtg acatttccat cagcatctgt cgttcctgaa
    15181 gcaactggtg taccaggagt caaagactgg actgcttgtt ttgctgcatc cacggacgct
    15241 cctttatctc gttgcgcata aaattcttga gtgacgttat aaactgaaaa tgaaatatcg
    15301 gctaatcctt ggtattgatc gaattcgctc atttctttcc cgctgttttg gattaaagga
    15361 tcgggtaaat cagtcatttt ctttttatga aggatgactt gagctgctgt ctcctctgca
    15421 aacacttttt ttgcgccgaa gctgtttgtg agtaatggta aaataaggaa aaggactcct
    15481 aacataacgt ttattttttt atgatttttc attttttcac tcctgttctt tttttgataa
    15541 acaaccagat tgcaaagctt gcgaatacca taccaacaac gcctaaaagt gtatttttcg
    15601 tttcgtttgt ttttggaaga aatggacggc tattttcttt tttattgact actttcaata
    15661 tactgtccgc ctctttatcc tcagaaagaa aagttgaaat ggtaaacgga atttctgttt
    15721 cacttaaaat ataaccagaa ggtgcttcga tctcttttaa tcgataactt cctgttttca
    15781 acccggaaat tgaaaaagcg ccatttttat cggaaatcag gtgaagcgca tctgattcgt
    15841 tctttgtcca cttgtatccg ttggctgttt gctggaggta atttcctgct ttgtttttaa
    15901 taaggaatac tgcgccagct aatcgtttat ctggtttatt tgtctcgatt ttgacaaatt
    15961 gcttactccc tgtatataca gagactttct ttgtactgac accaaaacca aaatccagtg
    16021 ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact gcttagctgc atctgataag
    16081 aaatggtcag tttttttcca gcatattttt ccaacgaagg gatcgaaaat aaaacatcaa
    16141 atccgtgagg tttcttgtgt atgacaaagc cttctgtcag cttttctcca ttcgatgaaa
    16201 tcgttaaact attaggtaaa aacgttaatg cttcatccgc actatctgac aattcgaact
    16261 tttgatagtc aaggatattt acaggaattg tcgtatgcaa ggaataagtg attttttcac
    16321 caatcgtaaa atcatttcta ggctcttcta ataccttctc aaaaggtgga tcagggtagt
    16381 cgttttcttc atttttagga tacaaatgga tagttgaaag tttttgattg ttttgtccat
    16441 gtacaggaag aacaactacc atattctctg ccttttcttt gacgacttct ggtactttgg
    16501 attcaatgaa aagatacgct ttatctcttt tttcttgatc tttagcggcc agagaaaaag
    16561 aagcgatacc atcttcgttg ttaagagttg tagttgttgc ttctgcggta aacataccgg
    16621 aagacgcacc gttttttgcg atctctgctt gtgcttcttc taccgttttg cccttttccc
    16681 gtagatggta aaaagaatct gtgacatcat aaacttggaa tgtgacacca tttaatcctc
    16741 gatacgtttg taataaagct ttttcttgtc cgtcatttgg atgatttttc ggcagttgcc
    16801 cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat ttctgtttct gtttctgttg
    16861 ctacctgagt aaaagctggt ttaaatagta acaagaagag acacatacta agccaaccaa
    16921 gttttttcat atttagctgc cccctctttc ttttttcaaa aaaagatacc aaatagaaaa
    16981 cgcacaacca atcatcccta ctagatagat tcctaaacgg ccaattcctc ccgtttcagg
    17041 taatggtact tttgcctgat tcgtgatgtc taaagaaatc tggttgtttt tggctcctgg
    17101 tgacagaaca gattcatgat cttgtccatc cacttgaatt gacccatctt cgtgtataac
    17161 tatagtaact ggctctttta gaccttggta tccttctggt gtaaaagttt cggtcagcgt
    17221 ataagttcca ggttttaaat tttcgaatag aaaggtatct gtttcttgtc catcttttgg
    17281 cgattctaag tccatttctg gtccctgcag tctgaatttt gctcctttta atgtctgtcc
    17341 gttgtcttct tttttgtgta ccgttagatc aaacgctttt agtcgatttt gatgagtgag
    17401 cgtccataca ttatttgtca tctcggtatt ttttcccgtg taaatgattt ttccatattt
    17461 atcgatttgg aattcataat ttcccggcga agtatcatat ccggcaggac cagctgtttc
    17521 aacgactcga tatttaccag gtgtgagtga atcaaaactg gcaagacctt tttcattcgt
    17581 tgtttggctg tcaattggct gataagtacc atttgcttct tttttctgta gggaaaatgc
    17641 tgctccttta agatttatct ctttgtccgt cccttgcatc gcatacttac gtactgctac
    17701 aggaacttca acaaaaggat tttcaatagt caactggatc gtatcatcgg aagtagtgac
    17761 tgtttttcca tcaatggtta ccgtaccatc agaagcgatc ttgatttccc aagtagtctt
    17821 tttgcttaat ccatgccctt ctggagcttt tgtttctgtc agcgtatagg tcatttcttt
    17881 ttgcaatttg acattttctg gaagagaata ggttccgtcg ccatgatctg ttagtaaagt
    17941 atcaatagaa tctcctgtta atttgaaaac agcgccaata agatcctttt cacctgtaga
    18001 ggaatttttc gttattttca agtttaacgg tgtgaattgt ttagtatttt tccatgtcat
    18061 tgcatctatt tgttgagaat cgtatcctgg tacaggtaat tctttgattg tttggtaact
    18121 gaatgcttga ccttgattat tgtattgagg tagtgataat atctcttgat aactttctcc
    18181 gctatttgca gataatttgt caatgtctgc acgttcccac gtatttgttg tatctttagc
    18241 tggtttaatg attcgaatat atccgttttt ccaagctgca gcatttgtcg tatgttcccg
    18301 ttgaatctca aaagtaactt gatctggacg atcagctaga ttgttgtcaa attcttccca
    18361 taactttttg atgtgaagac tgactccggg agctttagca gatggtatac cgaattcagc
    18421 taattcattg gtatcaatgt ttggctggaa agttgtcctg ccgttcattt gataccagaa
    18481 atttggatgg aagtcctcat tttctgtttg gattctcact tggtaatgga tttggatttc
    18541 ttggtctttt cctaaataga tctgattgct cttgatggta tttccttcta tggaaataga
    18601 tggagtgacc gttgtaggac ttgtccccac actcttgact gaaagtgtac caggctgata
    18661 aatgaatggt tctgcgattg gatcatttat ttgtccattg cttacagttg ctgagatctg
    18721 tacagctttt ttggctaggt attcagagat atctgttgca tgatcagctg attcatagta
    18781 aagatcgcct ttttcatctg atgaaaccat ttgtcgcata cgagactcta cttctgcttt
    18841 tgagagacca gctgccggat cgctttgaag ttggatgcca agaccatgta tttcgattcc
    18901 tcgttctttg agtgccatcg cttctccgat ggttgcgata aacgtactgt cgattcttct
    18961 ggatagattg ttttggtcag gtgcatcata gattcttgag attagagaag tatttcccgg
    19021 ccgatcttgc gtattagaaa actgagttcc gtaataattg ctgcttgatt gtgcgtgtac
    19081 ccgctgtact ttataggaaa atgttggtac accatccgtc agcaaaacga tcactttttt
    19141 atgtccattt ggaacggata gcatgcttcc tgcatctctt agtgcttttt gtgtaaaagt
    19201 accaccattt gtccgtgaag gtgtaatgga ttttacttga tttttcactg aatcaaatga
    19261 acccatctgt actgcaccgt tactgtagct atatccttcg cttgagtagc cgacatatcc
    19321 catattgatt ttgtctgtga taccgctatc tgctaaagta tcgacaaaac gatcgacacc
    19381 aatctttact tcaccgatcc gattattgtc gttcatactt cctgaccagt ctacgaccaa
    19441 tacgagatca agaggcgtga tatctttttg tacatttcca cgagcattca aataaacatc
    19501 aaacaatccg ggtgtacttg tttcctttgc atactttcgt atcgcatagt ctgcttgatt
    19561 accggttcct ccatattcga tatacgaatg ggtccgatca ttaggatctc cattccaaga
    19621 atttatacca tcccattgat ttgttccgtt tttattgcct tgatgatcaa gaacatttgt
    19681 atttcctgta ggttgccaac tggctttagg ataagtgccc tgatcatctg ttgtatattc
    19741 tgtaggaatc gtttgattag atggcacact cacagctggc aaggataatg taggcaatgt
    19801 aaatgggctg acagaatttt cgttttcttt tgatgattct tcttctattt cgtctggctt
    19861 tggtactgac acatctgtat ctttcttatt ttctgtctca tcaataatgt catattcttt
    19921 attatcgacg atcagcttgt ttgcctggct gtggtaaagt gctggatcga ttggaaaact
    19981 cagatcgata gtttgtttag tgtttgatga gatttccaac gtaattttcc cgctatttac
    20041 ctgataagca tagccatctc cttcttttct ttccacatca cttaagtaat tttcgactag
    20101 accaatttct ttttctatct tttcagcact ggtgttattc gcatttagct tgatgttcag
    20161 tgcttttttt ccagactgat ccgaaatgac ttcagctgaa attgtttcta aaactgttgg
    20221 atcatctgta gtgtctgcta ttgcagataa tggcacaaag tttgataaac tcaatattat
    20281 cagcatgaaa ataactttca gtttcttccc tgtggtcgtc atttttcccc tcctttttct
    20341 ttttttctgt tttgacgtga atagtgaaaa ttattaaaat aaacaggcgt tacataattt
    20401 tatttatttt aatatgataa ttattatacg aagggcgcta aagggaatca caccaatttt
    20461 cataccaatt ggtttcattt atgaagttga ttccttcgat taatgagcgt ttcattgaaa
    20521 gaaaagggtt gagggagaaa aacatatgat caggttgttg gaaggaaact atagaaagat
    20581 ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg atgactaaaa aagaacttgc
    20641 caaacgaatt ggtagttcag aatctacatt tgtaaggtat atcgaagaga tcaaaatccg
    20701 ctggggaacg gatgtaacga ttcaatcttc acaaaaattg gggtatcgtc ttgaacattt
    20761 gaatgtacca gcttatttaa atgttctgat ggaaatgtcg caaagttcta caaacagtcg
    20821 tttattaaat gagattattg tcaatccggg taaaacgatt gagtattatt gtgaaaaaat
    20881 ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa tgcaatcaaa ttttagaaag
    20941 ctatttatta aaagtgatcg ttgaccaagg ttttcagtta actagcctta aaagtgagct
    21001 ccagttgcgt atctttgtta cctttttctt tttaagttac tacggaagac gcacgttgcc
    21061 atttccaatc gaaaaaaaga agatcaaaga aattatggtc aagaataatt gtcagatgaa
    21121 tttgtttcag gaagaaagcc catatgagca atctttcttt attatgtatt ttgttgtgca
    21181 tctcatgaga gaatcccaag gaactccatt tgaatggaaa gctggagact cttatgtaca
    21241 gttgataaat atcgataaaa aagacttctt aatcttgaaa aatctcttag gaaaattgaa
    21301 gtacagcagc tatataaaag tagtgaacta ttttgtcaat acgatttttt cagaattttc
    21361 ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa aatatgtcct actgttcgtt
    21421 ttcatccgct gattgcaaag aaaaaaacga agaatatgtt gttcaattat taacgcaaat
    21481 ttattttttc tcccgtattt tcccatacga tacgactcat ttgacgatcc gtgcaactta
    21541 ctttgcacag cagatgcaac accgccagat acgtctatat gctggatttc gtgcagaact
    21601 tcaattttat tccactctac tgaatcagaa tctgatttat tatttatcta gctatatctt
    21661 ttggatgctt atcggtaatc ctgaaattca ccattatact tctgataaaa aaatactgat
    21721 tatcagcgac ttaagtcttc gacatagtca atatattgaa gaatatatca gtgatattct
    21781 tgctgtgcat aaaattcact ctgagacaac tgctattact gaagatcagc tgtcgaaata
    21841 caatcttctc gagtatgatc tgatcgttac gaatcaaccc attttgaatg cccatgttcc
    21901 tcatatattg attgatgata gtgtgtcatt cgcaaatgaa gaagaactca tccgcttatt
    21961 cgagttatga ataatcaaaa aacagctatg tataaaccac cctgataaaa atttcaggac
    22021 aaatacacat agctgtttct ttttattgta ttccttcagc aatccaacga gatttatagc
    22081 gaaagtcttt taacaactct tcttttgtcc aattatttgc aatgagatcc gtcaaagtgt
    22141 tcattacgag ggtcatggaa aagtatagga aactaactgc ttcttccgac gattgaatgg
    22201 agaaatgatt gattcttaat aattccagcc atttttcgtt cattggagaa tcagccgata
    22261 gttctctacg tttggttgtc tgctgatcat ttcgctgggt taacaagtat aacctttgcc
    22321 aatagatact ttcgtgatct aagtcgcagc accactctaa atatttttcg atccccaaaa
    22381 agaaatgttg tttgttttcg ctaatgaatt ttaagatatc ttgatggact atgtgagaac
    22441 tgcttttgat cgtatacaaa taagcatctt ccaaatcttg aaaatattta taaaaagcac
    22501 cgcgcgacat ccccatcttg tcaacgattt ctgagacttt gacttggctg atgtgctgtg
    22561 agcaaaatat ctccagtaat aggtcatcga ttctctgttt ctttgcgttc gataaattga
    22621 aaaaagtttc ttttggcatc cacatctctc ctttatctct gattatacgt ggatagccct
    22681 tcattgtcat gaaggattca ttccttcttt ttctcttctt ctgtcaagta cccatcttcc
    22741 attcgataaa cgcgatcact ccattgaatc atacggacat catgagtaac cataatagtc
    22801 gctttttgtt tctcatgagc ttctttaact agtaatttga cgacttcata tgcatgatct
    22861 gtatccaaac tagctgttgg ttcgtctgct aagatcaagc ttggctcatt atataaagcg
    22921 cgagcaattg ccactctctg tctttctcca ccagaaaggt ctttaggata actattttta
    22981 agtgactgga tatctaaaga ttgcagcaag gaatcgattt ttgttgaatc ttcttttttt
    23041 gaagtaactt ggtcaactag ttcaaattgt tcctttaccg ttaaaaaagg aatcaaatta
    23101 gagctttgga gaataaatcc tatttcttta aagcgtaaat ctgctcgttt tttttctgga
    23161 agctcagtta gtgagtgacc gttgatcact atttctccgg aagtcggtgt ttgcaatcct
    23221 cctgaaatgg taaggaaagt acttttacct gaaccagaag gaccaatgat gctgacgaat
    23281 tctccttcct ttacataaaa atcaattgct ttcaaagctg agacctttgt atgaccagaa
    23341 ccaaatgttt tggtaacttt tttcatcgtt aatatttttt tcatttttat taacctccta
    23401 ttgctgtaat tgggtctact ttggttatcg tacgtatcga aaacaatccg cctagcattg
    23461 cgacaatgat caaaatccca ctatatagca accattgtga ccaaaaaaca gcaaaaggca
    23521 tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa aagagcaagc agaacgccta
    23581 ccaccccaac aataaaggac tgtgctacta aagatttagc gatgaagaaa tttttgatcc
    23641 cttgtgcttt cattactcca aaaatagcag tcttctgaag tgtcatcacg tacatgaaaa
    23701 taccgaccac ggcagcaacc actaagaaca aaaagtatat catcgcattt aaggtcatat
    23761 tttgggcaga atagccagga atactttcaa tgaatgtccc aatagttaat aactgtagac
    23821 ccttcgatgc tttttctttc gaaattttag ctgaatcctt tattacgatc ccattgatcg
    23881 gctgttcttc ttcagaagca aacggctgtt gtccatactt caaagcagtc cacgtatcta
    23941 gggacgcata gatgacggga gaaactgtgt aataagtttc aggaaagata ccgacaatcg
    24001 tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc aattttatag cctgaatcag
    24061 ccagattttg agagatgatg atttcattct ttgttttaaa ttcatgccct ttcgtgagtt
    24121 ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt aacattttct ttgttttttc
    24181 ctttgattgc tccgctgtac aatccgattg gtgctttctc tcctccttca atgtatttca
    24241 gatctcctct tgttaattgt gaagctgcaa atacttgatt tgcatcctcc gacaaaacaa
    24301 tctcttgtgc gtcccaatca tcgattgctt ttttaaactc ttctgaaagt ccattcgcta
    24361 gtcctgacaa catgaatacg acatacgcaa tcaagaacat aataccgacg atcaagccat
    24421 atcgtaattt agaatagcga atttctttga tagctagaaa catttgtttt tcctccctat
    24481 gatagattga tagtgacaaa atgtcacttg ttgaatagtg taactctaaa gtgacaattt
    24541 gtcacttgtg ttgttttttt cttatcaata aattgtctaa gacatctttc gataaaacct
    24601 taacatgagt cataaaaaat ttatttaagc cttatttatg ctttccatga taaactaaag
    24661 tgaccaaatc aatgaggtgg gaaaatgatt aaactattag tagtagaaga cgataaagta
    24721 ttatccaata atataaaaga aatactcgct gcaatcggcg agataacaca agtttatgat
    24781 ggtagtgaag gactgttcga gttggaaagt ggagtttatg atcttgcaat cttggatttg
    24841 atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa tacggaaaga aaaaatacag
    24901 actccagtat tgattttgac tgcaaaagat agtttggaag ataagattga aggatttgaa
    24961 cgaggtgcag atgattatct aacaaaacct ttctatcgag aagaactgat catgcgcgtg
    25021 aaagcattat tgaaacgctc gctaggtctc tttgatgaaa atgttctgaa gtataaggat
    25081 atcagttgtg atttaaaaag caatgaagtc ttgtataaag aacaagtttt gcccatacaa
    25141 ggaaaagagt ttgaattgct cgtttatttt ttacaaaata agggaatcat tttgacaaaa
    25201 gagcagatat ttgaccggat ctggggattt gattctgata cgacgattac agttattgaa
    25261 gtttatatga gcaacttacg aaaacatctg cgaagtactg gattggataa agaaatcaaa
    25321 accttacgta atgtcggtta tatactgcaa agggtgtgat gcaatgaatg gagatattac
    25381 acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca gcatttgctt ttatcttttt
    25441 tcttttggga ttcattactt tacagatatt aaaccaatct gcatacagag aaacagatct
    25501 gtcattagag aaaataaatt ttgattctcg aacagtacaa ttagagatac aaagatatca
    25561 gcaaggcgat ccctttttaa acccgactca aacggaacaa aacagaacaa acatggaaca
    25621 gccattaatg gaaccatcaa atgaccgttt taacactcaa gtgatcttgt ggtctaaaaa
    25681 tggtgagata ttgaataaag cagctattgg tgggcgtttc aaccaaatca aagaattaaa
    25741 aatggatacg aaaaatctga ataccatcca aaatattgaa ttaaatgaag acagtggctc
    25801 atctgccctc tctttccgtt cgattacgaa aaaagcggag acgaatcaag atggcgttgc
    25861 ctacatccaa attttagaaa atacaaatca aatcaagaat tcattagcga cttttcgcac
    25921 gattatgatt ttgtgtatga ttgttttttg gattctctct attggtatca gttattactt
    25981 gtctagtcta agcatgcgcc ctattattct ttcttggaga agacaaaaag aatttgttga
    26041 gaatgcttct catgaattgc gcacaccgtt aacgattatt caaaatagtt tggaacatct
    26101 ttttaccaag cctaatcata ctattattga agaatccgaa agcatcgctc aagcattgtc
    26161 agagacgagg cgcctcactg gattgacttc ggatttgctg acaatcgctc ggaatgattc
    26221 tgatcagcag ctgctttcaa agcaaatgat caatacacaa gaatatatcg aacaacttgt
    26281 taaaccattt caagagatgg ccatcataga tggaaaagag tttattctcc ataacgatgc
    26341 aacattagaa gtaccaattg atgaaaaaaa aatccatcaa gttttggtta ttttgctgga
    26401 taatgcatta aaatatacga atccagaaga taagatcatt ttggattcat ctgttaacca
    26461 taaagaatgg ctgattcacg taaagaatac tggcccttct atcagtgaag aagatcaagc
    26521 aaggattttt gatcgatttt atcgggaaga tcaatctcgg gcgaaagaga ctggcggata
    26581 cgggcttggc ttggcaattg caaaacaggt aatcgaacag catcatggac agatttctgt
    26641 atccaattat cttccacaag gagtcgattt taaagtccaa ttgccgttga agcctaaaaa
    26701 ataatgctta tccctaaaaa agggctgtga caaaaatctt gtcacagccc ttttttgttg
    26761 cgaataaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt ctttaagctg
    26821 accacttctg tcacaacctc tttagcttac gcttacgatt ttttattgcg gtcttcaatg
    26881 tgtacatcac cgcttgtgtc aatatccaat tcttctcggc taacatcttc tgtcactttt
    26941 tcaacatctt catgttcttc tttatgaatc ccaacttctt cacgaataac tgtatgtttg
    27001 cttacatcta cttgctcttc tttgattggg atagtaatcg tgtcatcttc caatttttcg
    27061 tctgttccct gtgaagattg atctgttact ggtttgcgtt cgatgacgat ttcttcacgt
    27121 ttgaccggta cttctaccgt ttcagtatcg ttgaccacat gtttgtggat gtcgacttct
    27181 ccagttgtca catcatgtgt atttacatct aatttttctt cttttagttg aattgtatca
    27241 tcatctagat ttggtttgcg atcgatgtct tcagtcttgc ttgtacccat tgtatcagtc
    27301 tcgccaggta cgtccatcgg atcagttcct ggtgtcatat tcaatggatc cgttgtattt
    27361 tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc cagtgccagt ttctaatcca
    27421 gtccccattg tgcttgctgg gctaacagta tcttgtgtat ccattgtatc ttctgttgtt
    27481 tctggctgac gatagccttt tactgtgatg acaaattttc catcagaaat atctcctcta
    27541 tattgatata aaggatcatt ttctggtgta gccgtctcag aatcataggt atcaaaagaa
    27601 aaagtatctt ttattttttc ccataaagaa cggtcttctt caccatccat ccgattttca
    27661 tctgtttcaa catctatacc agacaatccg tcaaatccta gtctagatgc tgcttcatca
    27721 gtagtataaa taacgatatc atctcgttca tacccttcgt tacgcaaccg ttcaattact
    27781 gataatgctt cttccctcgt actatagctt ccgatgaccg ttaaattttt ctcttccatg
    27841 taaattcctc ctagcaaata gatttatgat tggtatattg ttacttataa
//
LOCUS       DAFLWZ010000031        27649 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000031 DAFLWZ010000000
VERSION     DAFLWZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.031"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            80..1339
                     /gene="lysA"
                     /locus_tag="L1V38_001431"
     CDS             80..1339
                     /gene="lysA"
                     /locus_tag="L1V38_001431"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBN1315986.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1326..2126
                     /gene="dapF"
                     /locus_tag="L1V38_001432"
     CDS             1326..2126
                     /gene="dapF"
                     /locus_tag="L1V38_001432"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBN1315987.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2129..3010
                     /locus_tag="L1V38_001433"
     CDS             2129..3010
                     /locus_tag="L1V38_001433"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBN1315988.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3007..3723
                     /locus_tag="L1V38_001434"
     CDS             3007..3723
                     /locus_tag="L1V38_001434"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBN1315989.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3729..4424
                     /gene="dapD"
                     /locus_tag="L1V38_001435"
     CDS             3729..4424
                     /gene="dapD"
                     /locus_tag="L1V38_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBN1315990.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4440..5441
                     /locus_tag="L1V38_001436"
     CDS             4440..5441
                     /locus_tag="L1V38_001436"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBN1315991.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5438..6799
                     /locus_tag="L1V38_001437"
     CDS             5438..6799
                     /locus_tag="L1V38_001437"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBN1315992.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6759..7910
                     /locus_tag="L1V38_001438"
     CDS             6759..7910
                     /locus_tag="L1V38_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBN1315993.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7885..9054
                     /locus_tag="L1V38_001439"
     CDS             7885..9054
                     /locus_tag="L1V38_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1315994.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9229..10608
                     /locus_tag="L1V38_001440"
     CDS             9229..10608
                     /locus_tag="L1V38_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1315995.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10889..11686
                     /locus_tag="L1V38_001441"
                     /pseudo
     CDS             10889..11686
                     /locus_tag="L1V38_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11875..12543
                     /locus_tag="L1V38_001442"
     CDS             11875..12543
                     /locus_tag="L1V38_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBN1315996.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(12743..12973)
                     /locus_tag="L1V38_001443"
     CDS             complement(12743..12973)
                     /locus_tag="L1V38_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1315997.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(13100..14482)
                     /locus_tag="L1V38_001444"
     CDS             complement(13100..14482)
                     /locus_tag="L1V38_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1315998.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(14638..15825)
                     /locus_tag="L1V38_001445"
     CDS             complement(14638..15825)
                     /locus_tag="L1V38_001445"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBN1315999.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(15832..16863)
                     /locus_tag="L1V38_001446"
     CDS             complement(15832..16863)
                     /locus_tag="L1V38_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1316000.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(16909..18333)
                     /locus_tag="L1V38_001447"
     CDS             complement(16909..18333)
                     /locus_tag="L1V38_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316001.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            18508..19413
                     /locus_tag="L1V38_001448"
     CDS             18508..19413
                     /locus_tag="L1V38_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1316002.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            19504..20181
                     /locus_tag="L1V38_001449"
     CDS             19504..20181
                     /locus_tag="L1V38_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1316003.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            20178..20348
                     /locus_tag="L1V38_001450"
     CDS             20178..20348
                     /locus_tag="L1V38_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316004.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            20462..21358
                     /locus_tag="L1V38_001451"
     CDS             20462..21358
                     /locus_tag="L1V38_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1316005.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21413..22783)
                     /locus_tag="L1V38_001452"
     CDS             complement(21413..22783)
                     /locus_tag="L1V38_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316006.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            23021..23767
                     /locus_tag="L1V38_001453"
     CDS             23021..23767
                     /locus_tag="L1V38_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1316007.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            23764..24603
                     /locus_tag="L1V38_001454"
     CDS             23764..24603
                     /locus_tag="L1V38_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1316008.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            24604..25554
                     /locus_tag="L1V38_001455"
     CDS             24604..25554
                     /locus_tag="L1V38_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1316009.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            25695..26447
                     /locus_tag="L1V38_001456"
     CDS             25695..26447
                     /locus_tag="L1V38_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316010.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            26466..27617
                     /gene="queG"
                     /locus_tag="L1V38_001457"
     CDS             26466..27617
                     /gene="queG"
                     /locus_tag="L1V38_001457"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBN1316011.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         9078 a         5035 c         5819 g         7717 t
ORIGIN      
        1 attattccaa taaaattcaa atctttatca aatgaaattc caataaaaac ggaaaaaaag
       61 tgaaaagagg aatgaaaaaa tgacagaatt gataattggc ggagtcacag caagcacatt
      121 ggcagaaaag tataagacac ctctgtatgt gtatgatgaa gaaaagatga gacaaacgat
      181 gctgtcattc aagcgaggct ttgtatcgaa acgttttgat acaaaagtgc tttacgcctc
      241 taaagcattc caaacgattg agatgctgca tttagttcgt gaatatggat tcgggctaga
      301 tgttgtcagt ggtggggaaa tctataccgc tttgcaagct gattttccta gagatactat
      361 ctacttccat ggtaacaaca agacgccaga ggaactgatc tatgcacttg aaaatgattt
      421 gttgcatatt gttgccgata atttgatgga agttgaatta ttagcagaat taagccaacg
      481 ctatttaaaa aaaatctgta tcatgcttcg gttgaatgtc ggagtagaag cacatactca
      541 tgaatatatc gtcactgcgc atattgattc aaaattcggc atgagctatg aaagtaaaga
      601 gtgccaacaa gcccttcagt tgataaaaga aagcagctat ctagagttag aaggatttca
      661 tgctcatatc gggtcacaaa tttttgatgt tactgcttgg ttagctgaaa tcgacaaatt
      721 gacgaattac ttaaccgatt ttgaccaacc tctttccttg aatcttggcg gagggtttgg
      781 gattcgttat acacaaaatg atcagccgat cccagtcgaa gaggcactaa aaaaactgat
      841 tgaatatacg gaagaagctt tggaaaaacg aaaactgacc attcgtcaat tactgatcga
      901 accgggtaga agtattgttg gagaagctgg tacaacacta tacacgattg gtttcatcaa
      961 aaagacacca cataaaaaat attactttgt agatggcggg atgacagata atatccgtcc
     1021 agctctgtat caggcagaat acgattgtga tttagcagca aaactgtcgg aagaaaaaac
     1081 agagaaagtg acgattgcag gaaaaatgtg tgaatcaggc gatgtggtaa ttaaagaagc
     1141 ttatttgccg aaagcagaat cgggtgatct tttagctgtt tattccacgg gagcttatgg
     1201 atactcgatg agcagcaact acaatcgagc gacacgacca gcagttgttt ttgtcaataa
     1261 tggccaatca agactgattg ttcgcagaca agcattttct gatctactaa ggggggaagt
     1321 ttcctatgat ccttcataaa tataatggct gcggaaatga ttttatctta ttagattacg
     1381 cagaagacac agattatagt caattagccg cttctttatg cacaaaagaa aaatatgata
     1441 tagacggatt gatcgccgta aaaatcgatc cgttggaaat gatctattac aacaaagatg
     1501 gcagccgcgc gccgatgtgc ggaaatggca ttcgctgttt tgctcgatac gtaaatgatc
     1561 agaacatgat gaatgaacag gaattcaacg tagagacatt agcaggcaca agaaaaatta
     1621 cggtgttgga tccctcacct ttttattgca gcgtagatat gggagtgcca gatgattctc
     1681 cggaaaaaat caaagctaat caaacttatc caataaaaaa ccaggaaata gagatcaatg
     1741 gtgaaaaagt aacgatcact agtttatttt taggaacgat tcataccgtt gtttttgttg
     1801 aaaatgcgcg tgaggaagtc tggagaaaaa gaggtgaact gatctgtcat catcctttgt
     1861 tcaaagaaaa aaccaatgtc aactttgtag aagtagtcaa tgaacaagaa ttgatcgtcc
     1921 gtacctatga aagaggagta ggttggacac ttgcttgcgg tacaggttgc tgtgcctctt
     1981 atgtggttgc taaggaaact gggaaaattt cagcagatca ggtagttgtt cacttggaac
     2041 aaggagactt gatgatctct ggtgaggatg cgatacaaat ggctggccca gcagttcatg
     2101 aatggacaag aatattggag gaatgaagat gataaaaggt tcgatcgtgg cgctgatcac
     2161 gccgatgaat gaagagggat cagtagatta tgctggtttg gaaaaattga tccaattcca
     2221 tttagatgaa caaacagatg gattattagt tttaggtaca acaggagaat cttctacgct
     2281 cacacaatct gaggaggagc agatccttca actgacagta aagaaagtgg ctggccgtgt
     2341 gccggtgatt gcaggagctg gaacgaataa tacgaaagaa acgattgaaa aagcgaagca
     2401 ttttgcttct ttgggggcag acgcactttt ggtcatcacc ccttactaca acaaaacaag
     2461 tgatgcagga ctagctgctc attttacagc aattgcagaa gcctcaccga ttccgcttat
     2521 tttgtataat gttccttcta gaacaggcat gtcgattcca atccatgtat tagtaaattt
     2581 agcagaacat cctaatatca ttggtttgaa agaagcctca ggagatatgg cttatgtgat
     2641 ggatgccgct cggttgattg gagaagaatt cttcctttac agtggaaatg atgatttgat
     2701 cctaccagta atgagtgtag gaggaagcgg tgtaataagt gtatgggcga atatccaacc
     2761 taaaatagtc catgaattag taaaagatac gcaggacgga agatggcagc aagcaaaaga
     2821 aaagcaatta aatgcacttg aactgatcca tgccttgttc agtgagacca atcctattcc
     2881 tgtcaaagca gccatgtcat tattagactt accttccgga cctctacgcc tgcctttagt
     2941 ttctctttca aaagagaaaa agaaacaatt agctcagctt ttgttaaaag aaaggacggt
     3001 tgaaaaatga aaatcggact gattggcagt ggacagatgg gaaatagagt cgaagaagtt
     3061 gcacaagaaa gaggagatac ggtccttctt ttacggacgg cacctaaaga agcaactacg
     3121 cttgctttta cggaactgcc agaactgctt attgattttt ctcatccaga taatttagag
     3181 aaaatccttt cgtatagctt atcatatcaa cttccgttag tcattggcac gacaggttat
     3241 acacaatcac agttccaaga aataaaagaa catgccaaac atgtacctgt gatgtatagt
     3301 gctaattttt cgttcggcat catggtgatg aatcaactaa tcaagcaagc agctgcaatg
     3361 ttgcaaggct ggcagatcga actgattgaa aaacatcata gtcgtaaaaa agatgcacca
     3421 tctggtactg caaatatgct gcttcaaaca atccaagaag tgcaaaagct gcagcccgta
     3481 tacaactggc aagggaaaaa aagagaagaa aaccaaattg gtgtacacag tattcgtgca
     3541 ggttctttac ctggtgaaca tgatgtattg tttgctgcta ctgatgaaat atttacgatc
     3601 aaacatgaat ctttttctaa tcgaatcttt gctgcaggcg cagtagaagc agcggactgg
     3661 ttgaaagatc agtcaccagg ttattacaaa ttagaagatt tattaatgga caaaggggtg
     3721 taaaaaacgt ggaagctcaa gaaatcatcc gctacattca aacggcatct aaaaagacgc
     3781 ctgtgaaagt ctatctgaat gtaaccgagc caatcgaatt taaagaaagt aaagtttttg
     3841 gtgaaggaag cagcttcgtt gtttttggtg actatgagac gattgctccg gttttagaag
     3901 ctgaatcaga aaaaatcatt gaaatcgaaa tcgaaactgc tgcaagatac agcgcagttc
     3961 ctttgctaga tattaaaaaa attaatgctc gtatcgaacc aggtgctatt atcagagatc
     4021 aagtgtcaat cggcaacaat gccgtgatca tgatgggagc gattatcaat attggtgcag
     4081 taatcggtga aaacacgatg attgatatgg gtgctgtctt aggtggacga gcgacagtgg
     4141 gcaaaaactg ccatattggt gcaggagctg tcttagcagg tgtgatcgaa ccagcatcgg
     4201 ccaaaccggt tatcgtagaa gacggcgtac tggtaggtgc gaatgcagtg attgttgaag
     4261 gtgtccatat cggaaaagat gcagtcgtgg cagcaggagc agtggtttta gaagatgtgg
     4321 cagcagaaac tgttgtcggt ggaatacctg cacgtgtatt aaaaataagt gatgatcaga
     4381 caaaagaaaa tacagcattg attgctgcgt tacgcgaatt atagaggaga tggagaaaaa
     4441 tgcgcgaaat agatacctgt attgtggggg caaccggatt agtcggccaa acgatgctca
     4501 aagtgttaga agaatatgat tttccagtag gacgattgaa attattagct tcaaaacgtt
     4561 cagccggtaa agtttgtgta ttcaagaaaa agaaacacac tgtacaggaa ttgacagaaa
     4621 cttcatttga aggatatgat ttagcgctat tttctgcagg tgcttctgta tccaaagagt
     4681 ttgcgccaat cgcacgaagt cagggactat ttgtcataga taattcctca gcatggcggg
     4741 aagattcgga tattccatta atcgttccag aggtcaatct ggaagactat acattgaatc
     4801 ggctgattgc aaatccaaat tgttcaacca ttcaagcggt acttccgctt aaagctttac
     4861 aagaagcctt tggtatccag cgagtcaatt attcgaccta tcaagcagtt tctggttccg
     4921 ggcaaaaagg cattgaagat cttcatcgta cgcaaaatga cgaggaacca gttttgtatc
     4981 cttataatat tagccaaacg gtgattccgg aaatcgatca gcctttggaa aatgggtata
     5041 caaaagaaga acagaaaatg ataaatgaga cccgtaagat tctgcatcag cctgctttgc
     5101 cagtatcagc aacctgcgta cgtgtgccaa tcgaaaatgg acatggagtc tctgtggcag
     5161 ttcaactgca aaaagagttt acgacggaag aaattagaga gtgtctcagc cagtttccag
     5221 ggattcaatt agaagatgat ctagcagcac ataaatatcc gacgagcatt cttgctagag
     5281 gaacagatat ggtttatgtt gggaggatca gaaaagacac ttctttagag aacggattgt
     5341 tgttctatac gactgccgat aacatacgca aaggagccgc tgcgaatgcc gtacagattg
     5401 ctgcagcttt aatgcagaaa atagcggagg tggcaagatg agtaatacgc tgaaagtagc
     5461 gaaattcggc ggaacatcga tgtctcatga agagcaattc aaaaaagtcc gtacaattgt
     5521 tctttcagat cccaatcgcc aagtgatcgt tgtttctgct ttaggcaaac gtacgtcaga
     5581 tgatgacaaa gtaacagact tactttattt gatttatgct taccttcagc atcatgttga
     5641 ttggacaccc ctttggaaaa ggatttgtga tcgtttcatt caagtaagag atgttcttgc
     5701 cctgcagtta cctattgaag atgaactagc acgcatacag aaacaactgg aagacgaaaa
     5761 gataactgaa gattatttag taagtagagg tgaatatctg actgctcaac tgatggctga
     5821 gtatcttggt taccagttta ttgacgcaaa agacctgatt ttctttgact atgatgggaa
     5881 aatcgatcag gaaaaaacag cacaggaaat cacaaaagca tttaaaagat atccgaaaat
     5941 ggttgttcca gggttttacg gggcgaaccc tgcaggaaaa gaaaaattat tgggccgtgg
     6001 gggaagcgac attaccggcg cgatactggc gaagatgttg caagcggaaa gttatgagaa
     6061 ttggacggat gtttcaggaa tcatgatggc tgatccgcga atcatcgatc atcctaaaat
     6121 catcgaggaa atctctttta gagaactgag agagatggct tatatggggg ctaacgttct
     6181 tcatgaagca gctgttttcc cagttcaaga ggctgatatc cccatccaaa taaaaaatac
     6241 caatgatcct ttcgctcaag ggacaaaaat atcgaatcac gaaatagaaa aggaaaatgg
     6301 actgacagga atagctggac gcaaggattt tctttccatc actttattca aacgtcatat
     6361 gtccgatgaa atcgggttta tctggaaagc aatgagcatt tttgctaaac atgagatatc
     6421 aatcgaacat attccttcag ggatcgacaa tatcggagtg atcgtctcag cagaagcgat
     6481 tgccgataag ttatttctca tcacgaaaga attaaaagaa acacttggcg tggaagaaat
     6541 cgtcgtgatc gaagacttag ctttgatctc tgtcgttggg ggtccgcata aagaattgat
     6601 tggattatct gggaaagtgt tatcgatatt gaacaaatta gaaattcgca catcgatctt
     6661 atcacaagga gcacaggagt tgaatctgat catcggtgta ccgaataatc aatatgaaac
     6721 agtagtgaag ggtatctatg aagggatggt gaatacggat gctgaaagaa tatcgaatgg
     6781 cactccatca aattcctgaa atcgggtttc atgaattcaa gacaaaaaaa tatttatatg
     6841 aacaagtaaa aaacagcgag gccgttatcc atgaaatcgg cgaaacagga ctactccttt
     6901 attttgataa tcagcaagaa gaaacgattg cttttcgaac agatatcgat gcactgccag
     6961 tcaaagaaga aacgaatctc tcttttgctt ctaagcatga aggttatatg catgcatgtg
     7021 gtcatgacgg acatatggcg atgcttttag ggttgactga ctttataact aaacacattg
     7081 aggatcttat ttataatgta gtactgatct atcagccatc agaagaaatt tccggtggcg
     7141 cacaaagcgt tattcagtca ggattgttgg ataaatatga agtacaagca atatttggct
     7201 ttcatctatg gcctggacta gctaagggag aagttttctc tcgaccagga cctttgatgg
     7261 cacaaagcag tgaaacagac attatcatta aaggccagtc tgcacatatt gcttctagtg
     7321 aaaaaggaat cgatagtctg gaggcagctg tacgattttt gaagaatgtt tatgattttg
     7381 accggcaatt accggcagag tggaatcatc taatgaaatt tggccaaatc caaggtggaa
     7441 cgatccgaaa tgttttagct ggagaagtta ttgtatccgg aagtatccgt tcttacagtt
     7501 cagatatgca aaattatttg aagaggggat tagaccattt agcagaacag tttcactcta
     7561 cagctactat ttcttttcgc tataatgacg gctatccagc tgtaatcaac catagaggct
     7621 tatatgcagc actgttagat tcaaacaaac tacatgaatt agatgctcca gttcttcaag
     7681 ccgaagattt tggcatatat acgcaacaat atccatgtgt atttttcttt ttaggtgtcg
     7741 gtgatacccc tgctttacat gatccgacgt tcgattttga tatggatgtt ttagaaaatg
     7801 gtgtagaatg gtacaaaacg attcttttta cagaaaatct tcttgtaaaa atcgatagca
     7861 gttcaaaaga ggagcgagta aataatgatg aatttatcca atcgatttag tcctaggctt
     7921 tctagaatag aagtatcaaa aatacgacaa ttcgatcagc aaatatcgtc gataccagat
     7981 gtgatcaaac tcaccctggg agaaccggat tttccaactc ctgaacatgt caagcaagca
     8041 ggaatagcag cgattgaaga agacttttct cactataccg gaatgagagg attagaggaa
     8101 ctgcgggaag cggcttgtat atttcagcaa cagcgttatg gattaactta tgatccgcaa
     8161 acggaagttt tgacgacagt tggtgcaacg gaagcgattg cctctgcgtt gttatctgtt
     8221 ttggaagaag gagacaaggt tcttattcca gcgcctgctt attcaggata tcagccatta
     8281 gtggaactag ctggtgctga attgatcccg atagatactt ctgacacagg gtttgtctgt
     8341 cagccggaac aatttgaacg agcatttgaa caatatggat cagctgtcaa agcagtcatt
     8401 ttaaactatc ctaacaatcc tactgggacg acattgtctg caaaacaatt gaaagcaatc
     8461 gctgaggttt taaaaaaata tccggtattt gttataagtg atgaagtata tgctgaattg
     8521 acttatagtg gaacgcatat gtccatagct acttatcttc cagaacaaac aatcgtgata
     8581 agcgggttat ccaagtcaca tgcgatgact ggttggcgag tgggctttat ttttgctcaa
     8641 aaagccctta ttgacgaact aattaaagtc catcaatatc tggtgactgc cgctacaacg
     8701 atgtcgcaaa aagctgcggc tgaagcgcta ataaatgggg tgaaagatag cgagaatatg
     8761 aaagagcaat atcaaacacg aagagactat ctggtccagc aattggcgcc tttaggattt
     8821 gaagtgaccc agccaaacgg tgcattttac ttgttttgca aactcccagc tgccattcaa
     8881 actgactctt ggcagttttg tgtagaatta gcggaacagg caaaagttgc gtgtatccca
     8941 ggaattgcat ttggcccaga aggagaaggt tatatccgga tttcttatgc tagcagcatg
     9001 gaaaaattac atgaggcctg caaacggatc aaagactttt taacagaaca gtgattcata
     9061 gattttatca aaaaaacaat cgttaatttt gcggtatatt ctgcaaggag acgattgttt
     9121 tttaaattta gttcaaatga acgcgtttct tttgattcat aactaatgta atgttaagtt
     9181 taaattgttt agaatgattt taaaagaata ttcaaggagg tttcatcaat ggaaaaaatc
     9241 aaagttgtca ttgtaggtgc atctcatgga gggcatcaat cgatcttgga actattgaca
     9301 cgatacggtg aaaatgtaga tatcacgcta tttgaagcag gagactatat ttccttcatg
     9361 tcatgtggta tggagctgta tttagaagac aaggtaacag atgtaaatga tgtacgtaat
     9421 ttcagaccag aaaactttcc gcaatccaat gttcatattt taaataatca cgaagtaaaa
     9481 acgatcgatg ccgataaaaa aacagtaacg gttactagcg catcagataa cgaaacaaaa
     9541 gaatatcctt atgacaaatt gattttgagt tctggtgtca aaccaaacaa tctgccagta
     9601 ccaggagcag atctagaaaa tgtctacttg atgcgtggat acaattgggc aaccaaaatc
     9661 aaagaaaaat taaatgatcc ggctattaaa aaaatcgctg tcgtaggtgc gggttacatt
     9721 gggatcgaag cagcagaagc aagccgaaaa gctgggaaag aagtcgtatt gcttgatgtg
     9781 atcgatagac ctttaggcac ttatttagat gctgagatga cagatatttt agaacaacac
     9841 ctaaatgaaa acggtattga agttttgaca aatgcaaaaa tcgaagcttt tactggtaac
     9901 ggaaaagttg aggcaatcaa aacaagtgaa aaagaaatcc cagcagatct agtcattcaa
     9961 gctgccggtg tgaaggcaaa tacagaatgg ttaaaaggga tcgtcgactt agatgaacgt
    10021 ggctggatcc aaacaaatga atacttgcaa acgaatcttc cagatgtgta tgcagtagga
    10081 gatgctacac ttgcttattc tatcccagca cgcaaaaaaa tgccgatcgc tttagcgact
    10141 gttgcacgta gagaagcacg ttatgtagta aaacatcttt ttgaagaagt accaaacaaa
    10201 ccgttcggcg gagtcgtagg ttcctctgca ttaagtgtct ttgactatca ttttgcagca
    10261 agcggattga atagctttac agcagcaaaa gcaggagtag atgtacgagt gtcttattat
    10321 gaagatacgt tacgaccaaa atatgtacca gaagaacaag gaaatccaaa agtgtccatc
    10381 caattattct cggatccaat gacccatcaa ttgctaggag gagcagtatt atctacctat
    10441 gatgttacag gtcaaggaaa tgtattggca ctagcgatcc aaaacaaact gactttagaa
    10501 gaactagcag aagctgactt cttcttccag ccaggctttg accgacaatg gagcatgttg
    10561 aatctagccg ctcaacaagc gttaggagaa gaaccatttg tagaataaga aaacgaaata
    10621 tttgaaaaga ggttgtgaaa aagctgcctt gcatcaagta ataagaacag ccaagtaaaa
    10681 acagcttctt atgtttttaa cttggctgga cttattaccg cagatgcaag cttttgaaca
    10741 ccgtttattt tcaaaaaagg gactgtgaca cgatttgtgt accgaccccc aaaagttaga
    10801 ccaaaaaatc taacttttgg aggtcggtat tttttatggt taaatatact tttgaactta
    10861 aattaaagat cgttcatgat tatttggatg gcaaaggcga ttggaccgta aaaatccaga
    10921 tcaagagatt gaagcggaaa tgcttaaaat tcgggagaag cacaaggatt atggctgttt
    10981 acggatgacc aatgaactaa gaaaccgcgg tttctctatc aataaaaaga aagttcagcg
    11041 cttgatcaag aagctaggaa taaaagtaac ggcatacacg cgtaaatcac gtcgctacaa
    11101 ttcttatcga ggaaaagttg gagcagtagc caaaaatcgg atccatcgtc gtttctacac
    11161 cagtatctgc catcagaaaa tcacgacgga tacaactgaa tttaaatacc atgaagtgga
    11221 tgccaaaggc attatccgtc aaaagaaatt gtatctagat ccttttatgg atatgttcaa
    11281 tagtgagatt ttatcctatc gtatctctga aaagcccaat gcattagcgg taatggaagg
    11341 tttggaggaa gctatccaga ccactaacga ttgtccctat cgtcgtacgt ttcactcaga
    11401 tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa ttgaaggagt acaaaatctt
    11461 tcaaagcatg tctcggaaag ggaactgctt agataattca cttatggaga atttttttgg
    11521 cttattaaaa caagagattt ttcacgggaa agtttataac tgtttcgagg aattaaaatc
    11581 agccatcgat agctatatct attactacaa taatgaacgg ataaaacaga aattaaactg
    11641 gcaaagtctc gtccaatttc gtaaaacaac cgtaacggtt gtgtaaaaat atcattttag
    11701 agcataaaaa aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact
    11761 acagtgtcac agtccttttt ttagtaaaag gatacatttc ttccttgtat attccatgcg
    11821 tgttcgtgag aaagcatata taatttaatt aacagatagt tagggggaga aaaaatgatt
    11881 ttttcaatta caatgaaact ggtgttcggg ttgatcggtt tattattagt ggtacgtttg
    11941 cttgggaaga aatccatgtc agaaatcaca ccgtttgatt tagtctatac gcttgtttta
    12001 ggtgggatct tagaagaatc aacctatgat gacaatgtcc atgtagggca tgtcctattt
    12061 gccattgcgc tttgggcagt aatgatttat ggtatcgaac gtatcgtcca aaaaaatgaa
    12121 aaggtcaatc gttgggtcaa aggcgagcca tctgttctaa tcaaagacgg cgtcatcaac
    12181 atgacagagt tgacaaataa ccatatcgag atggagcagt tgcgagcaat cttaagacag
    12241 caagaatgct tttttcttga aaatgccaaa catgttatcc tagagaatgc cggtcaaatg
    12301 agtgtattga aaaaatcaga tgaagacaaa gctttatcga tcctgcttgt agatgaaggg
    12361 caaattcagc ataaagtgct tcagtccaat caattgactg aagcatggct tatggagaac
    12421 ttgaagaaag aaggctatgc agatgtaaaa cagctgattt atgttgaatg gtcagaagaa
    12481 aaagggctct acatactaaa taaagaagac gtcatgcatg aatcttaccg aatagatgga
    12541 tagatagaca gaggttgtga aatcagcgcc ttggcttgtt actcaaaact aagcgacttt
    12601 ttcacaacct ctgatatcta atatacgttg ttccagaagt tgcttcttcg aaaaataagc
    12661 caaaattcca caaaaattta agaagcaatt ttcgaaaaat cctttcttat tttttgaagt
    12721 tgatcacttc tgtcacaacc tctcatgtca caaaccattt ttttgtttcc tttaactcaa
    12781 tataccgtac gtcttcccac aatatcggct gatggtcaat cataaagtaa tcttcatagg
    12841 cttcaccaat gaagtgccct tcgacctcat ccaagagtct tccaaattca tcttttaaat
    12901 tgagctgaat gattactgct ttacgagata aaaaggcttc tgtcagtata ctatcgattt
    12961 cttgcaatgt catttgttgt ttaggaagag gctgtttgcg tgcttcttct tcattttttt
    13021 gataccgttg actagttctt ccatcgcaaa agcagtcccc cattttaatc caaatggccg
    13081 atctcgatac tcgttatagt caatgaattt ttttgctgtc cgtctcatct tttccacctt
    13141 ctaatccact cataccacct gcatgcccgc caacgagaga actacgtgcg atggcgcgtc
    13201 ctccttgcaa gagactatgc gcatggatga ttgattgaaa gccgtatttt tttctaatcg
    13261 tatcgacaac aaaatcaact ttcgcttcat ttatctgctt ttcaggatct tcaaaaaggt
    13321 taagctgtaa acctgtcgcg tatacgaggt cggaacagtt cacgcctaca cgccgaatat
    13381 cctggtagtg gtaatgctgg tggaaaatgg tcaataaagc atctgcaaga tctctgctag
    13441 catttgtcgc ttcgattttc atttgctggt gaaacccggt cttgccattt ggatcaagat
    13501 agcctaaaga gtatcctacc cataagctga ctacttgtgt ttttgctgca gatcgtctca
    13561 agcgagtgcc gacttggtcg gccatttctt tgataacgat ctcgatttct tctcgtcttg
    13621 tataatctct atctaggatt tgactatttc cgatactttt tgattttggt gtatattctt
    13681 gtcccaaaaa acttcgatcg atgccccaag catgggcata aagctgagta ccgatgaccc
    13741 ctagcttgct tttcaagtga taataatccg cgtgagctaa atcataaaca gaatgtatac
    13801 ccatttgttt cagacgtttt gctgttcgtt tgccgattcc ccaaaagtca gtgatatctg
    13861 agattttcca taacttttct ggtacatctt cataacgcca ttcagcaaac atttgctttc
    13921 cgtcttttga gccattgtct aaggctagtt tagcaagtag cgggttatcg ccaattccta
    13981 tagtcgtgta gattccggtc tgctcaaaca catctttatg gatcagttta gccatgtcgt
    14041 acgcatttgt tttaccaaag agtgccatgc tatttgttac atcaaggaag ctttcatcga
    14101 cggaatagac atgatggttc gcttcgtctg catatttttt atagatagaa ttgatttctc
    14161 tgttcttttc catataatag gccatccttg gggcaacaat atataaatca cttggatagg
    14221 ggaagggaag atctctggca cggctgatat tggtgatgcc gtaagctttt tttgctgcag
    14281 gactggaagc caagattaat ccgctacccc gtgtttctgt cgaatcggac ggataggaca
    14341 tgactactaa tttagttgta aggggatcaa gatccttttc aacgcactct acggaggcgt
    14401 aaaaagattt gcagtcaata cataaaatat ctcttgaagg ttctttttca taaacaaata
    14461 ccggattttg attcgcccac ataacaatca cctcttcaac acaattagaa cacacgttct
    14521 ctttccgtgt caataaaaaa cagcaatttt caaatacgag caaaaggctc acatttggaa
    14581 attgctgaga ggttattttt atctatttgt ttttagctga gatcgttgat ttttttatca
    14641 aacatgaaca gcttctggat cgatctttgt tgtcccattt ccaatgtgtg caacataaaa
    14701 ttccggagca tagccgacaa ctttcatgta ttcatcatag acattgtttt tgaaggcagg
    14761 tatattttct tctttgacaa gagcaatcgc acagccacca aatccagctc ctgtcattcg
    14821 tgcacctaag acaccttctt gtttttgagc agcatctact agtgtatcta attcgatccc
    14881 agttacttca taatcatagc gaagagagtg gtgagaatca tttaacagtt gaccaaatgc
    14941 ttctaagttc ccagcttcta attcagcttt tgccttcaaa gtccgctgat tttcagaaac
    15001 ggcatggcga gctctgcgta tcaatgtatc atcgccgatt tggtcaatag ttgattcaaa
    15061 ttcttcttca tctaagtctc ctaaagaaga gataggcaaa gttttttgca aacgtgccaa
    15121 ggcttcttcg cattcgctac ggcgttcatt gtattttgaa tctgccaatt cccgccgctt
    15181 attcgtattc atgatgacga ttgcataacc atctagtttc actggaacca tttcgtattt
    15241 cagcgtattt gtatctaata agattgcatg atctagctca ccgaagccga tggcaaactg
    15301 atccatgata cctgaattga caccgatgaa ttcattttct acttttttac ctgtttggac
    15361 tagttccaag cgatctgttt ttaaatcaaa cagatcttct aatacaacac ctactaataa
    15421 ttctaatgaa gcgctactgg aaagtcctgc accattaggg attgttcctt ccactaataa
    15481 ctcaaaccca tgatcgattg agtgtccagc ttcttttaat ttaaggacca ttccttttac
    15541 gtaatttgcc cagtttgctt ttttatcata ttctagctca tctaaagtaa aactaatgac
    15601 accgatatcg tcaaagtttg tggaataaac taatatttta ttatcgtctc gaggtgctgc
    15661 tacaccttgc gttccataag tgatggaagc ggggaagaca tggcctccat tgtaatctgt
    15721 gtgttcacca atcaaattga tgcgtcctgg tgagaagtat tgtgtagttt ttttaggtcc
    15781 gaatgtttcg gcaaattttg tgtttaagct tcttttgatt tccatgatga gttattcctt
    15841 tcttgttttg attttgaatt ctgttactgt ttcaaatact gatccggctt ttaaatgaat
    15901 cgaaccaaat gctgagaagc gctctgcacc tggagctgtt tgagtctcaa atgtgatgcc
    15961 accgtgatgt gccagttttc ggttgcgcat ttctggtgtt tctgtgccga aatttgcagt
    16021 gaaaataacc acactagaag catctgtagc aatatctact tggattcttt tatcggggct
    16081 agtcaagcga gcggcttctt tacccaagcc ggtttctttt aagaaaaatg gatgatcgat
    16141 tccgtcaaca agattttttt gatccaaatc actagcaaaa acggacgcta attttttagg
    16201 tatttgaaaa tcgaaagcac ttcctgcagc attttctttt acccctatag gaatactatc
    16261 tgttcgcaaa ggagcataag cttcgctatt gagccaaagc tcatgttgat cgattgactg
    16321 agaagcatct cccgtcaagt tgaagtaaac atgatttgtc ggattgaata aagtatcttg
    16381 gtcactggtg ccgcgagagg tcactcgcca gatattatct tttgtcaaag tatagcggat
    16441 ttccacatcc attgtacctg gaaaaccatg ttctccgtcg ggacttgtag tagtaaaaat
    16501 gacagaagct tcattttcgc cattcaaaat gacataagac cattttttta attcaaatcc
    16561 aggagcacca ccatgcagat tatgtccagt ttttggatct gtggctaatt ggtaagtttt
    16621 tccattgaga gaaaagcggc cattttcgat tctccctgcg gtgcgaccga tagaagcacc
    16681 gatatacgga tctttttcga tatattcttc agcggtgtca aatcccaaaa ctaattctcg
    16741 atcatttgat tttaaactga cgattctagc acctaaatca gagatagaaa gtgctagctt
    16801 gtttttgttc tccaaggtta tcaagtgata accttggcca aaatcttttt ctgtaatctt
    16861 cattttcaag atcctttctt aatgggaagg aactactgca tcgtgaagtt aatcttccat
    16921 tgtatcagct ggagccaatt tgttttccaa tttctcaacg atttgtgcat gttttttctc
    16981 tgtcaatgta atcttccaag caaaaataat agcggagaaa atcatcaaag cagcaggagc
    17041 atagaatgca taagctttga aagtcgttac gccatgagca gtgatatcag cagcagtagc
    17101 attaccagtc atcccagaag cgatagcgac aaaccctacg atcccgttag acaaagcacc
    17161 agcgatttta tctagtaaag ggcgaattga tagagtaaca gcttcgttac ggataccatt
    17221 tttccattga ccatattcaa cagagtctgt gatcgtcatc aaagcggata agaaaatcaa
    17281 ttgttgaggg aagtagaaca atactagccc gatgataacg attggcaaac ttgaacctgc
    17341 gatcgtaaag aaaaagtaag aagaaatcat cattgcgatc cctccaaggt aaacgtagcg
    17401 acgagagatg acgcgtgtaa gcattgggaa tagtggaaca gctactaaac caagtaaggc
    17461 agcaactaga ccaacgatcc aaaattcagt tggttggcca agtacatatt tgaagaagta
    17521 gaataatacg gcagttgttg ctgcattggc aatcgcataa gcgatataag caagggcaag
    17581 ccacatcaac tgatcatttt gagcaactgc tttgaacaca tctttgatcc cagctttttc
    17641 attttgctga cggatcgcag tatcgacttc ttttgtgccc aaggcagtga taatcgcagt
    17701 accgcctgaa ataacagcag caatcacacc gaaccagaac cagcctgaag cgccttcaat
    17761 atgtttatga gtaacaagat aggtaaagaa agtaacgata gggacaacga ctagagtagt
    17821 accatttgca cctagagaag agccgaaacg agcaaacgta gcaaattttt cacgttcctt
    17881 tgtttccgta ctcaaagctg gaatcattga ccaaaaagcg atatccttaa atgaataaaa
    17941 actatccaat aagatgaaaa cgattgcaaa taatatgata aataaagtcg tattatgagt
    18001 agctaagcca aagaaattgg taaagattgc taccaagagt acggaactaa caacgccgcc
    18061 gataactaac catggtttga atttaccgta ttttgtacga gtattatcga tgatgccacc
    18121 aatcaaagga tcaaaaataa tttcaactaa gcggatacct acaactaagc ttgtaactgt
    18181 agcaatcatt tttgcattcg ttgccttatc tgttcctgcg aacatctggc ttgtcacgaa
    18241 taccataaaa taagtgctta atgtaacata gaatgtgtcg tgtccaaaag cgcctaaagc
    18301 gtaggacaca cgttggatca ttttgctttt cataatctgt attcctctcc tgttcaatat
    18361 ataatactaa gtaaaccggt tacaacgaat aacaaagatc ttttaatgac ttaaacttaa
    18421 caagaaatcg cttccttttt aatatatttc tgtgactttt atttaacttt ttgttgcatt
    18481 atactaaagg agtaaggagg gatagacgtg gagcaatcga tttttttaaa aaaggaacat
    18541 caacaagtag aaaaagaatt gtattttgat ttttgtggtt tctctaaaac gatgccgttt
    18601 cattcttttg gtcctgctat tcgcaatgat tacatcctgc atgtcgtgat ggaaggcaaa
    18661 ggatcttatc atgtgaaaaa tcaacaattc caattgaaaa aaggtgatct gttcttgatt
    18721 cgtccaggag actcgacgtt ttacttatca gatggagaag atccgtggat gtattgctgg
    18781 ctttcatttg gtgggagtgc tgcagaagaa atcattcggc agtcgctttt cagagaagac
    18841 caatacacga tggtctcttc tgacatacaa aaatatatcg acattatttt agaatgcatg
    18901 aaagatacgg aagaaacctt ggaaaatgaa ttacagttaa cagcattaac ctaccgtttt
    18961 ttatcagtcc ttttaaaaga tggcggaaag gtcagcggtg gtgtacaaaa ggttcattcc
    19021 tctttagctg ttgaaacagt caaatacatc gaggcacatt atgctgaaaa attgtctgtt
    19081 gaggaaatcg cccagcattt agcggtcaat cggagccatt tgtcgcgagt attcaaaaat
    19141 catatgggta ccagtatcaa ggaatatttg atcggggtac ggatcaatcg aggggcgttt
    19201 cttctttctc tgacggatga atccgtggaa agtattgcct atcaagtagg gttcaatagt
    19261 ctagtcgtat ttagccgaat gttcaaaaag agtaccggag aaacggctac gaactatcgt
    19321 aaacgtatga aaaacgaaaa ttttaagaat attgctttgg ataccttgaa aaaacagttg
    19381 gaaaaacaaa ccgcagtttc ttggacaacc tgattagtct ggttaaaatg acaagcatcg
    19441 gcaaaagaaa cttgtggcgg ttatgctaca ctgtaaagcg aagactaaaa aggaggaaaa
    19501 gggatgcgta cacttatcat cattagccat ccaacgatcg aagaatcttt aaatcagcaa
    19561 tttttcaaag aagcttctgc tggtttacca gctacttggc atcatttgga atcaagttat
    19621 ccagacggaa aaatagatat agagactgaa ctacagctct tggcccagca tgatcggatc
    19681 attttccagt ttccgtttta ctggtatagt tctcctgctc atttaaaaat ttggcaagat
    19741 aatgtcttgg aacgagcagc acatgtatta aaagggaaag aactaggaat cgtattgaca
    19801 acaggtgtgg cggaaaaaga ataccaagct ggaggaaaag aagaatatac gatttccgaa
    19861 tttttgaggc cgtatcagcg aatcgcaaat aaattccata tgacctatct tccgccattc
    19921 gttttagcac aatttatgta tttatcccag gaaaaacgtt gggagaagct aattgcttat
    19981 cagcagtatc tctcattgga aggcaaacca tcgctgactc agcggattga ctggtttatt
    20041 caaagagtac aggaaaatca gaaaatgcag gaagaagaat ctgaaaaaca agcatatatc
    20101 gtagaagcac tgactgaggc aaaagagcag atcgaagact tgacctttac actgcaagaa
    20161 atgaaaggaa cttcattatg acaaatgatt ggctgatcca acaattagat gaattaagcg
    20221 aaaaatcaga atatcaagac cgtgcgctct tatatgaaat aaagaaactg atggctgaga
    20281 tagacgaacg aacaatgcag ctgcaaggag aaatcgacgg acaatcttgg aatcatctca
    20341 actggtgaaa ttttcttata aataacaaag ataaaaatgt gcacagcgac aattatttgc
    20401 tacaataaga atatgaagcg tttgataacg ctattataca taaaaattgg tggtgaaaaa
    20461 aatgtatgat gaaaatgagt ggggagaaaa tgttcggatg acccgaagaa gacagcaaaa
    20521 acaggcagct cgtaagcgga tgatcatgat tggggcagca gttgccgtgt ttttgatcat
    20581 agcaggagga gttgcgggtc tatattttca tggaaaaaat tcgtcagaag cgaaaagtac
    20641 gaccataacg gaaacaacga caaagaaaac agagacgaaa caaacaagtg agtcatcaac
    20701 taaaacaaaa gagacacaaa cttctgaaga aaaaacagca aatggtttgc cagagcaact
    20761 tcaagcaatc gtaaatgatt attcgaaaaa gatcgaagaa aagacgcctg cattgattga
    20821 agaataccag acagaaattc agggaaatca agagggaata gctggtttat cagcagttgc
    20881 taaccaaaaa gcacgtgagc ttcaagcaat ctccgacgaa gggatcagaa aattacgtgc
    20941 agcgtatcag gcagcagaaa ataaagacgg tgtagactta gatactttga tcaatcaatt
    21001 atcggctaat tatacgaatc atgtcgctaa gatttccgat atttatttgc agactagcgc
    21061 ctctcttcaa gcagagtcaa caagcacaca agacacaaca tcttctgatt ctgagacagc
    21121 agagtcggta gaagcttctg aaatgcaagc tcgaacaaca caagacacaa cagattcctc
    21181 tgaaactaat accaacagcg cgacttcaca ggctgcgaca accgtagttt tggaaggaga
    21241 aggtccaaat caaatagccg aacgaactgg cgtaccagta gaaacgatct tgtcgctgaa
    21301 tgggatgagc atggagaatt atttcctgac tcccggtgag acgctaaaat tgaattgata
    21361 aaagcaataa aaaagaacga agcttccact aaggtgaagc ttcgttcttt ttttattttc
    21421 cggttctttt ttcgcgtaca aagtaatgga tcgtcatgta aagcaagaaa acgagtccaa
    21481 taatcaatga gattctcgtt tcaggattga taaacatgaa aatcaatacg atagctaaaa
    21541 aagcaagtgt cacataattc gtataaggag atagtggcat tttaaaagga tgatcatgca
    21601 ttttatctgc gtgcttcttt ttgaagcgaa tctcgctgat caaaatcact acccaaggaa
    21661 ccataccagg caaaatactt gagctgtata cgaaaacgaa aatattttct gactggttga
    21721 tgaacattgg tagaagataa tttaagatca gaccaattaa gattccacct gagattgcta
    21781 cgacaggata aaaaggcgca ccgtgacgag atagtttcag aaatttttta gacatctttc
    21841 catttatggc aagtgtatag accatacgac ttgcgctgaa aatccctgaa ttgcaacctg
    21901 ataatgccgc tgtaatcacg acaaaattaa tcagtcctgc agcaaatgta atgccgactt
    21961 tagaaaaagt ttgtacaaaa ggtgaaccaa tctcactcaa ttgattccac ggatagatac
    22021 tcacaatgat aaaaatagca ccaatataaa aaatcaagat tcgaccgata gtggactgga
    22081 cagcttcaat gatcgtcttt ttaggattct ctgcttcacc agcagtcatt ccgatcagtt
    22141 cgattccttg ataggaagca acaacgatcg ataatgcaaa gaaaaatcct ttgacgcctc
    22201 cagtgaagaa tccaccattt ttccaaagat ttgaaatccc tactgcctga ccatgattac
    22261 caaatccaaa taagattacc ccaagacctg caatgatcat caaaatgatc gttatgactt
    22321 tgatgatcga aaaccaaaat tctaattcgc caaacgcctt gacagaaata agatttgcca
    22381 gcataagaaa caagacgaca atgattccgg gaataattgc cggcaaatca ggccaccaat
    22441 aattcatata agatcctaca gcaatcactt cacttattcc tacgacaata tattgaaaaa
    22501 tattactcca agcggtcaag tagccagcca caggatggat gtactcgctc gcgtaatttg
    22561 caaaagaacc agtcgaagga tcaacgtaaa gcatttcgcc taaagcacgc ataatcaaat
    22621 acaaaaagaa tcctgcaatc gcataggctc ccatcactga gggccctgtc caacgtatgg
    22681 ttgaggaggc acccataaac agaccgacac cgatcgttcc acctagtgcg atcatttgga
    22741 tatgacgggc actaagactt cgagttaact tttcttcttc catacaaaaa ctcctttcgt
    22801 tgttgagtca acaagaaaaa ataatcaaac gtttcaacac atgtttttca ttattaggtt
    22861 agccttattg aactcttgat gtgattctac agaaaatttt cataaaatgc gaggaaaatt
    22921 cgaaaaaaac tttttcatca ttctacttga aaatgctttc cattttagtt aaactatatt
    22981 taaataaaaa gttaggtaaa cctaaaaagg agtgtaagat ttggaacgta cggccattgt
    23041 aattcaagac ctttcagccg cttatcaagg gaaaactgtt ttgaaaacta tcaacttgac
    23101 gataaatcca caaaaaatta ccggtattat cggaccaaac ggtgcaggaa aatcaacatt
    23161 tatgaaatct ttgctagagt tgataccagc tactactggt aaagtcacct tttctggaca
    23221 gtcggtaaac tcagtccgta aaaaaatagc ctacgtggaa cagcgaagtg aattggatct
    23281 ttcctttcca attgatgtat taggcgttgt acttttagga acatatccat ctttacgaat
    23341 tggacaaaga cctgggaaaa aagaaaaaga acgtgcaaga caagctttga aaaaagtagg
    23401 gatggaagaa tatgccaaaa gacagatcag cgaactatcg ggtggacagc ttcagagagt
    23461 ttttattgca agagctctag cccaaggagc agaatggatc tttttagatg aaccattcgt
    23521 agggattgat gcgttaagtg aacgaaagat ctttgacatc ttgcaggaat tgaagaattc
    23581 aggaaaaacg attttgatcg tccatcatga tcttcataaa gtagaagaat atttcgatga
    23641 ggttattctt ttaaataaac agctgatcgc ttccggtcca gtacaagaag tctttacatc
    23701 gaagaacctt caattggcct atggtgagat catcagacat ttagtaaaag gaggagagaa
    23761 aaaatgatcc aatcctttat tgatggatta atgaattatc aattcctgca atacgctttg
    23821 gtcacttcca tgcttgtagg acttgcttct ggagtcatcg gttcttttat tattttacga
    23881 gggatgtctt tgatgggaga cgctatctct cacgcagttc ttccaggtgt agccatttct
    23941 tatatgtttg gttttagtta catctttgga gccactgctt ttgggatgct aacagcagca
    24001 gtgattggtt tcgtgactca gcggagccga ttgaaaaatg atacagcgat tggaattgtc
    24061 tttagctcct tttttgcatt agggattatc ttgatttcat atgcccagag tgcgacagat
    24121 ttgtatcata ttttatttgg gaatgtctta gctgttaggg aaagcgattt gttgctgaca
    24181 gcactcgtta gtggaatcgt cttgatattt gtctttttct tttataaaga attgaagatc
    24241 acatcattcg atccgacaat ggcaaaagct tatgggctga acacatcgct gatccattat
    24301 cttttgatgt tctttttgac attagtggct gtagtcagtt tacagacagt aggaacaatc
    24361 ttggtgattg ccatgttgat cacaccagcc gccacggctt acttgctaac gaaccattta
    24421 ctgaaaatga tcattacagc tgcaggaatc ggtatgctaa gtgcagttgt cggtgtgttt
    24481 ttcagttata gttacaattg gccatcagga gctacgatcg tgttagcatg taccgcattt
    24541 tttatccttg cttttttatt ttctccaaca aaaggaattt tatttcagaa aggaagcaga
    24601 tagatgaaaa caaaaaaatc actcttttta atcttggcag ttagtttctt ggtattagcc
    24661 ggttgcggaa agcaggcttc tgaccaagcg gatgaaggaa gtaaagaaaa gttgtcagtc
    24721 gtggctacca attcgatctt ggcggacatg gcaaaagagg tcggaacaga tcaaatagat
    24781 atccacagta tcgtaccagt cggaacagat ccgcatgaat atgaagtact accagaagac
    24841 atcaaaaagg caagcgatgc agatgttatt ttatacaacg gtttgaatct tgaaacaggt
    24901 aacagctggt tcgataactt gatggaaacg gctaaaaaag aagaaggaaa agattatttt
    24961 gcagttagca aaaatgtaga acctctttat ttaactagcg gtgaagaaca tacaaaagca
    25021 gatccccatg cttggctaga cctatctaac ggaataaaat atgtggagga aatcgcacgt
    25081 atattctctg aaaaagatgc agaaaatgcg acactctata aaaaaaatgc agaagcatat
    25141 gtggaaaaac taaaagaatt agatacacaa gcgaaggaaa gttttgcttc tatcgaagag
    25201 aacaaaaaat tattagtaac aagtgaaggg gcattcaagt atttttcacg agcatatgat
    25261 ttgccagcag cttatatatg ggagatcaat acagaaagtc aaggtacgcc tgatcaaatg
    25321 aaagcgatca ttgatcagat aagagcaaaa gaagtaccgg ttttattcgt ggaaaccagt
    25381 gtagactcaa gaagcatgga acgggtagca aaagaaacgg gtttgaaaat ctatgataaa
    25441 ctgttcactg attccatagc aaaagaagga gaacaaggag attcttacta tcagatgatg
    25501 aaatggaata ttgaaacgat ccatgaaggt ttgtcacaaa caaaagaaag ctgaaaagtg
    25561 caaggtctag cttgaggagc agaccttgca ttttttataa gagatatgaa aaaaaattat
    25621 gctgtttttc gtcgtacaga tacctttttt gaagaaattc cgttatagtt agagtaagga
    25681 aggaaggtgt ggctatgaat tttacacgta aagataaata tacgattaaa gaagaagtct
    25741 ttcgattgat cagccagcag gaaaataccg acaaggatca agaccttcaa tttcttgaag
    25801 cagaattagc taaattattc atagcaaatc aaaatgagac aacagaacca gatgaagagc
    25861 tgtacatagg caaatggttg tttgatgaat ttcagccttt agatgaaaat accggtatcg
    25921 gttattttgt gttcctttct ccagtcggct tcacacctgg cgtattagtt aaacaaaacg
    25981 acgaaataac cgtcaaagca tggcctgcat tattttcagt catcaaagca gaaggagtaa
    26041 tcaaaaagat ccagtcggcc tattataaaa gtcaatttat tgccaacagc aaattaatga
    26101 atatgtttta taatcgtcta gtagaaattg ctaggcctgg gaaaatcccg caaacattca
    26161 cgtacacaca gcaaaaaaat ctctatgaag aagtattgta ttcccgcgat ctgtctgagt
    26221 tttcgccatg ggaagaggta aggctccatg aactgttaag tacaaaacca gtttcattga
    26281 atttttttaa tgcattagat aacaaaagaa aattaatttc aacaaattat tgggaagtat
    26341 ttgctgcaag aaaaaaatgg atggaagaaa agaagattgc cgatcagcag atccagtttg
    26401 tccagctgaa aaaagaaaaa ctatattatg ggttatacag ccgttaacag caagcgagga
    26461 agaccatgac attaaaagaa gaaatcatac aagaaagcaa acgattagga attgacaaaa
    26521 tcgggttcac cacggcggaa ccttttgatt cattaaaaga atcgttggaa gaacaaaaag
    26581 cagctggcca tacttctggc tttgaacatc caaatatcga tgagcgtctt tatccagaaa
    26641 tgacatttga tcagccgaaa tcgatcattt ccattgcact tgcgtatcct actaggatcc
    26701 atgaagaagt gcctagggat gaaaaacgcg ggcagtttgc tcgtgcttct tgggggatcg
    26761 attaccatga tatactcaga gaccgtttga accgattgat cgaattcatc caaacaagag
    26821 cagaaaaatg gcaaaaagaa gaggaatggc gtctagctcc gcaagtagat actggagaac
    26881 tgatcgatgt cgctgtagca cagcgagctg gtttaggatt tattggacga aacggattgt
    26941 tgatcactga agagttcggt tcatttgtct atcttggtga gatcgttact aatattgtat
    27001 ttgagcctga taaaccagga gaatttggtt gcggtgactg tatgcgctgc gtgactgctt
    27061 gtccgacaaa agcattgctt ggtgacggaa gaatgaatgc ccagcgatgt ttgtcttatc
    27121 aaactcagac aaaagggatg atgccggaag aatatcgtaa aaaaatgcga aatgtcattt
    27181 atggatgtga tatctgccag ttagtctgcc cttacaatca aggaaaagat tttcattttc
    27241 atgaagagat ggaaccaaaa gtagacgaaa tatatccaaa attaaagcca atgctttcga
    27301 tgtctaataa agacttcaaa cagcaatttg ggcatttagc tggttcatgg cgtgggaaga
    27361 aacctttgca gagaaacgca ttgattgctt tagctaatct aggtgatcga acggcattgc
    27421 ctgagatttc agaatgttta acagatgtcc gccctgtcat cagaggaaca gcagcttggg
    27481 ctattggacg tctaggaaca aaagaaccgg aaaaatggct tgatgtatta gatgaaatat
    27541 tagctaaaga aacagaagaa gtcgttataa acgaattgga acatgcccag aaattattgc
    27601 ggagaaagtt aaaataaaaa aatagttaac attattcaaa gtttttgtc
//
LOCUS       DAFLWZ010000032        27646 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000032 DAFLWZ010000000
VERSION     DAFLWZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.032"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(342..704)
                     /locus_tag="L1V38_001458"
     CDS             complement(342..704)
                     /locus_tag="L1V38_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316012.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(778..1158)
                     /locus_tag="L1V38_001459"
     CDS             complement(778..1158)
                     /locus_tag="L1V38_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBN1316013.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1222..2415
                     /locus_tag="L1V38_001460"
     CDS             1222..2415
                     /locus_tag="L1V38_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1316014.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2492..3076)
                     /locus_tag="L1V38_001461"
     CDS             complement(2492..3076)
                     /locus_tag="L1V38_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1316015.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3277..4275
                     /locus_tag="L1V38_001462"
     CDS             3277..4275
                     /locus_tag="L1V38_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1316016.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4387..4896
                     /locus_tag="L1V38_001463"
     CDS             4387..4896
                     /locus_tag="L1V38_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBN1316017.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4926..5585)
                     /locus_tag="L1V38_001464"
     CDS             complement(4926..5585)
                     /locus_tag="L1V38_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBN1316018.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5587..6351)
                     /locus_tag="L1V38_001465"
     CDS             complement(5587..6351)
                     /locus_tag="L1V38_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBN1316019.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6359..7036)
                     /locus_tag="L1V38_001466"
     CDS             complement(6359..7036)
                     /locus_tag="L1V38_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBN1316020.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7073..8458)
                     /locus_tag="L1V38_001467"
     CDS             complement(7073..8458)
                     /locus_tag="L1V38_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1316021.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8668..8752)
                     /gene="ffs"
                     /locus_tag="L1V38_001468"
     ncRNA           complement(8668..8752)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="L1V38_001468"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8775..9290)
                     /gene="tadA"
                     /locus_tag="L1V38_001469"
     CDS             complement(8775..9290)
                     /gene="tadA"
                     /locus_tag="L1V38_001469"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBN1316022.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9396..10253
                     /locus_tag="L1V38_001470"
     CDS             9396..10253
                     /locus_tag="L1V38_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316023.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10334..10669)
                     /locus_tag="L1V38_001471"
     CDS             complement(10334..10669)
                     /locus_tag="L1V38_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316024.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10736..12106)
                     /locus_tag="L1V38_001472"
     CDS             complement(10736..12106)
                     /locus_tag="L1V38_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBN1316025.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12184..12720)
                     /locus_tag="L1V38_001473"
     CDS             complement(12184..12720)
                     /locus_tag="L1V38_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1316026.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13029..14510
                     /locus_tag="L1V38_001474"
     CDS             13029..14510
                     /locus_tag="L1V38_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316027.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14613..15320)
                     /locus_tag="L1V38_001475"
     CDS             complement(14613..15320)
                     /locus_tag="L1V38_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBN1316028.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15399..15737)
                     /locus_tag="L1V38_001476"
     CDS             complement(15399..15737)
                     /locus_tag="L1V38_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBN1316029.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15848..16810)
                     /locus_tag="L1V38_001477"
     CDS             complement(15848..16810)
                     /locus_tag="L1V38_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBN1316030.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16825..18156)
                     /locus_tag="L1V38_001478"
     CDS             complement(16825..18156)
                     /locus_tag="L1V38_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1316031.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18164..18844)
                     /locus_tag="L1V38_001479"
     CDS             complement(18164..18844)
                     /locus_tag="L1V38_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBN1316032.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19063..19542)
                     /locus_tag="L1V38_001480"
     CDS             complement(19063..19542)
                     /locus_tag="L1V38_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBN1316033.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19669..21348)
                     /locus_tag="L1V38_001481"
     CDS             complement(19669..21348)
                     /locus_tag="L1V38_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1316034.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            21896..23398
                     /locus_tag="L1V38_001482"
     CDS             21896..23398
                     /locus_tag="L1V38_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316035.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23411..24073
                     /locus_tag="L1V38_001483"
     CDS             23411..24073
                     /locus_tag="L1V38_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316036.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24174..24377)
                     /locus_tag="L1V38_001484"
     CDS             complement(24174..24377)
                     /locus_tag="L1V38_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1316037.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24488..25672)
                     /gene="iadA"
                     /locus_tag="L1V38_001485"
     CDS             complement(24488..25672)
                     /gene="iadA"
                     /locus_tag="L1V38_001485"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBN1316038.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25829..27568)
                     /gene="yfcC"
                     /locus_tag="L1V38_001486"
     CDS             complement(25829..27568)
                     /gene="yfcC"
                     /locus_tag="L1V38_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBN1316039.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         8230 a         5771 c         4677 g         8968 t
ORIGIN      
        1 tcttttttaa cgactcagtt atcttatcat gtcgttagta acatgtcaat aactattttt
       61 taaatttttt agaaatgtga tataacatcc acttcagaat caacgctgtt aaatttatca
      121 tgtatttctt ccttggtcaa ctataaatta agcattactt tgtgaaatga tttttcgatc
      181 aattattatt attcgttata caaccgtttt caacatattt tgaaaataaa atgcactaaa
      241 aaactatctt tagcagaaca tttcattgta ttttttggac caaacaataa aaaaagaagt
      301 ttgaaaaaaa ttcaaacttc tttgttcgct taatctgtat tttagaagaa aggcactccc
      361 tctacttcgt aagttccaag aacagagcgc atttgacctg gttcttccca aatatatcct
      421 tcgcctaatt cttctctttg attcttttgt tcagtttcaa agacaaacaa cggaacattt
      481 tcctctttaa tatgtgtatt tgtcaattcc atcaaactaa tcttgctaac atcgatatga
      541 actatttctt ttaagaaatt aagtatattc gctaaaccag tctttccttc agaaagttcc
      601 gctaacgcaa attccaactt gtcatcaatt gaatggacca aaaatttttt agtaccatcc
      661 tccaaatgca acataattgt accagcaact cttttgcttg ccaaaatttc cacctcgatc
      721 aacttgttct atggcttaca taaaaattct agcacatttt cagaaaaaat acacttttta
      781 tttcttattt tctttccgtt ctagttcaga taatgcttct tctatccaaa taggtaactg
      841 ctccgcaata gtggtaaatc cgatcttacg atttttattc gtgaaatacc tttttctgcg
      901 atatggaaca gctggatttg ttttttctaa cgttcttaaa gataaactga tttttttgga
      961 atattcatca atgtcgatga tctgaactgt tactggctgt ccgactttta acaatgaatg
     1021 gatatttttc gtataaccgg attgtacttc tgaaacatga ataagtcctt gcgtctcgtt
     1081 atcaagagaa acgaatgcgc cataaggctg tatccctgtc acttttcctt caattatttg
     1141 tccaatttta taagtcatct acttccctct cttcgcattt atcattatac tgtaaatagc
     1201 tcaaaaaaag aagcgacgaa aatgactgga ggtcttaaga tgatcgaatt tgataaacag
     1261 atttcaagaa aagatacaga aagtgtaaaa tgggacgcaa ttgctgagac atatcaaatg
     1321 gatgacttac ttcctttgtg ggtagcagat atggacttct tgtctcccgg tggggtagct
     1381 aaagcgttta gtgaatacat caaacatgga atctttggtt atgccactct gtctgataaa
     1441 ctatatcagg ctatcattca ttgggaacgc caacaccatg ctgtggagtt gacgaaagaa
     1501 aatatcgttt ttacaagtgg tgtgttaacc agtttagctg cagcagtaca aacttttaca
     1561 aaaccaggcg attctatttt gattcatgac ccagtttatc ctccattttc ctctattata
     1621 gaaacaaatc aacgtcacat cgttcgaagc tctttgctag aaaaaaataa tcatttcatc
     1681 atggacttgt ctgacatgga gaaaaaaatc gaagaaaaca atgtaaaagc aatgatttta
     1741 tgcaatcctc acaatcctgg agggcgtgtt tggagcaaag aagaattgaa acagttaagc
     1801 gaattgtgtt taaaacatca agtgattctg tttagtgacg agatccatca agatttaact
     1861 ttattcgatc atacatttac ttccatgcta acgattgatc ctaatttaga tgatctacta
     1921 gttgctttta cttccgcaac caagactttc aatctagctg caatcaaaaa ttcaatggta
     1981 tttatcaaaa atccagagat gaaagctgat tttgaaaaac atttagtgat gaaccaacag
     2041 cacgaaatca acacttttgg actgattgga acccaagcgg cttatgagac gggtggagaa
     2101 tggttaagcc aactgattcc ttatctagaa aaaaatgttc aaacagttaa tcagtttttt
     2161 gaacagtatc ttccgaaagt gagaataatg aaccctgaag gaacttactt aatgtggtta
     2221 gattttaccg cctatatttc agacgaccaa gaattggaga acactcttgt tcggaaagga
     2281 aaagtcgtat taaatcctgg catcacgttt ggtccttccg gtcatgggca tatgcgcttg
     2341 aatattgctt gtccagaaga aactttactg gaaggactta atcgaatcaa gtatgcttta
     2401 gagacaatcg attaaatcat ttattcaaaa taaaaggacg agaccttact aggtttcgtc
     2461 ctttttcata attactccgt accataccaa actattctga aatttcaatt gtttcaatca
     2521 ctacatcatg tacaggtcgg tcttgtggac cacgttgtac atttgcgatt tcatctactg
     2581 tgtccatccc ttctagtaca tgtccaaaga ctgtatgtcg gaaatctagc caaggagttc
     2641 cgccaccttt atacgcttca atgatttctg atgggaatcc agcaccttct agttgtccaa
     2701 gcatattagc tggcacattt gtgttattta caataaagaa ttggcttccg tttgtgtttg
     2761 gacctgaatt tgccatagat aaagctccgc gaaggttgaa cagttcacga ctgaattcat
     2821 cttcaaaact ttcgccataa atactttcgc cacccattcc tgttccagtt ggatcgccgc
     2881 cttggatcat gaaatcagga ataacgcggt gaaaaatcac gccatcataa taaccttttt
     2941 tggaaagttc aatgaaattt tgaaccgtct tcggtgctag ttcagggaat aattgaacag
     3001 taatgtcacc acggtttgtt ttgataacag cttttggtcc tttttcactt tttaaatcta
     3061 gttgtgggaa tgccatattg tttcctccta atatttgcat acttcataat aataataaca
     3121 taatacctaa cctctcgtaa aaatactaga tttgttttct tttatttttc atcactagat
     3181 acattctata acttaccgtt tcgatttcga attcaaacat ttttgagaag cattctcaat
     3241 taaattctga tatagtgtga aaagggagga atttttatgg aaatctatga cattacaatc
     3301 atcggtgcag gtcctgtagg gatgtttgcc gctttttacg caggaatgcg ccaagctaaa
     3361 acaaaaatca ttgacagtct acctcaactt ggtggtcaat tagcaacttt gtatcccgaa
     3421 aaatatattt acgatattcc tgggtatcca gcaataaaag caagtgaatt aatcgatcaa
     3481 ttagaaaaac aattaactac ttttaaccat acattccatt taaaagaaga agttctctcg
     3541 cttactcgtg aagacgaagt tatcgagatt actacaaata aaggcatcca ttattccaaa
     3601 gcagtcattt tagctttagg aaatggttca ttccagccaa gaaaattgaa tttagataat
     3661 gctgaatcat ttgaaaacca cggattggat tatttcgtga atgatttgat gaagtatgct
     3721 ggaaaaaaag tcgctattgc tggaggtggt gattctgcta tcgattggac gttgatgtta
     3781 gagcctattg caagcgaagt ttacttgatt catcgtcgcc cggaatttcg tgcgcacgaa
     3841 catagtgtat cacgcttgaa atcttcatct gtcaacttgc ttactcccta tctcatcgat
     3901 ggattatcag gcaataatgg ggaactgaca gatatccggt taaaaaaagt gaaaagtgac
     3961 gagacgattg atttgatgat tgattctctg atcgtcaatt atggattctc ttctaattta
     4021 gaacatcttt cttcttgggg acttgatagt accagaaatg ccattactgt aaaatcagat
     4081 atgtctactt ctattccagg cgtttatgca gctggtgaca tctgtaccta tgaaggaaaa
     4141 gtgaaactga ttgctactgg gctcggtgaa gcacctactg cagtgaacaa cgctttacac
     4201 tatattaatc caaaggaacg aactcagcct ggtcacagca caagcttata cgataaaaat
     4261 cttcgtccta gttgattttt tatatctctt tgcatttcaa gttaaacccg aaagcagttt
     4321 cttgcatttt tttcatgttc cgttaacatg aaatagagaa agaaaaaata aagggggagc
     4381 aataatatgg tcgtcaaaac tgagacttta gaagaaaagg caagagaact attgaaggaa
     4441 cgtggcgtaa ctgtagaaga tatcgcacaa cttgtcatgt ttttacaaaa agactatatt
     4501 tctgatttga ctttggcgga ttgtactgaa agtgtcaaca gcgtgctaac aaagcgtgaa
     4561 gtacataacg ccattatcac tggaatccaa ttagatatat tagcagaaaa gaaaaaattg
     4621 atgagtccgt tgcaacatat tatcgaagat gacgaaggcc tttacggtat cgatgagatc
     4681 ctagccttgt caatcgtgaa tgtttacggt acgatcggct ttacgaatta tggttatatc
     4741 gacaaggtga aacctggtat tttaaaagaa ctaaacagcc acgatggcgt tcatgtccat
     4801 accttcttag atgatatcgt cggagcgatc gccgctgctg ctgccagtcg attagcacac
     4861 aaagaaccag aaaaaagaag tcgccttact caataattca acaaaaaaag aaagaaaacg
     4921 tctatttaga cgagttcttt cttttttgtt tgtttcaagc tattttttcc taagaaaaga
     4981 aaaacagcaa aaaataattc taataataca aaaaataaga taaagctatg catgaaaaat
     5041 tcttctggaa gtacattgat gattggatca gtaacgggat cgaataacca gtcatcgttg
     5101 ttgaaaaacg tttcatgaaa aaggataaaa aagcgatcaa atcctatcat catgaaaaaa
     5161 ccgaaaacaa ctggcagtaa catgccgatt tgaaacggac gaatcaaccg ccaaagccga
     5221 tcattctttt gcaaatattt gataaacaaa atactcggga tcaaagtgat gaaaaacaca
     5281 gcataatcca ctaaaaacaa aattttcact tcataaaagt gatgggctcc gctagcagaa
     5341 actgggaaat ctggcaagct gaggatggtt ttgaagggat tattgagata attcattagg
     5401 tgatcaaaat ttttcagtaa cgtctcttga tctaaagaag tataatccaa aatttgcaaa
     5461 tgtccgatat caaatacgta tagtggtcga aagttgatcg tcacaccaac tgccagactg
     5521 atcagtgtca gaaataggct gaacaatcca gcatattcca tccactgcca tctcgaattt
     5581 ttcatattag aagctccatt catccagtga ttgtttcaca taggtagctg ggataggcaa
     5641 cccaggtaca tcttcttctt ttgtaaaacc tgataaaacg agcaaagtat ctatattatt
     5701 gcgtatccca gcttggatat ctgtttcata gttatctcca accatgatta cttcttcttt
     5761 ttgcagccct aatacttcaa cggctttatc cataatgatg gcttctggtt ttccgatgta
     5821 gatcggcggc gtttgggttg ctgtctctac aaaagagatg actgaccctg ctccaggaag
     5881 aaggccgcgt tcagtaggta tattcttatc tgggttcgtt ccaatgaaag tagcaccttt
     5941 ttgaatagca agtgttgctt taactacttt ttcataggtc agataattat ctaagcctac
     6001 cactacatag tcaggagcct cttcttccca tgtaaatccg gcagctaaaa tcaagtcaat
     6061 caatcctgct tctccgataa catagacttt tttccctttt ccatctgctt tcataaaatc
     6121 gattgttgcc aaagtagctg tgtagactgt ctctggagct acatgaatgt caaactcatc
     6181 tgctagacga ttagctactg tttctggtga cttagtcgtg ttattggtaa caaacaagaa
     6241 aggtaatttt cttttttgca attcttccac aaatcgttta ccggccggta tgggttgtgt
     6301 cccacgataa atcgttccgt ctaaatcaat taaatatcct ttatagtcca ttcatccact
     6361 actcttccct ttttctgatc gtaaatgctg tttttgtttt ttctacttgt ttaggttgtt
     6421 cttgtttttt tactttttca gaggtttttg ctgactctgt ttttcgattt ttaataaccg
     6481 gttttttgcg attagatgcg actggtcctt ttttctcatc gatatacgca cgattatggt
     6541 tttttttctt ttttcggcgc tgagttgtct tttctttttt accgccgatt ctctcgatga
     6601 caaaatacgc acaaccaaaa ttgcaatatt cgtaaagata gtcttccaag gaatcgattc
     6661 gctgatctgg atgcgcccgt cgattatccg cttggaaaaa tccttttagg cgtagttgtt
     6721 cataacccca atctcctacg atataatcat atcgggctag tacatcactg taacgttctc
     6781 caagcttttc tgcattaaat ccttcacgat aatcggacac aagccgataa tgtctttcac
     6841 ctatcaaaaa attactgtca tctaacagtg tcactagctc gcctttgact ttttctgctt
     6901 taggctcctc aacgatttct tccaaagcag ctgtcagttc ttcggtgact gttgtttcct
     6961 gttcagctga tgattttttc ttagcaattt ctgttttatg ctcaacgttc tgctgttcat
     7021 tttgttttgc agacatgcgt tcaccaccta tcttttttat tataccttgt ttttatttga
     7081 ttgggtagtg agctttcaag taatctccta ccacacttcg gataaattca gggaacaaaa
     7141 attcattttt tccagcaatc tcaatcgttg gaaaaaatgg aacaaacatc aaatgatcta
     7201 cggtagtaaa agtataattt ttattcagat cgattggctt gttcttccaa aagacttgat
     7261 ggttaataga atcatatgtg attccattat agaccatctg cccaaaaatc ttaccgcgaa
     7321 atcccattcc cttcatagga tagttacgta aaaagttacg atttttttct atttctaaaa
     7381 ctaagcggat cagatcattt ccacccaatg tgacatttaa caagtgcatc ggatgcggca
     7441 acgcagtgtg aagctgatcc tgattgaccc gcccttttgg aatttcagtt aaaaacagac
     7501 cactgtttaa tattgctgct tccgtctttc ctcgttcttt caccgcctca aaggctactt
     7561 ggataaacga atgctcattg aagatatcta gactcagaga aaatggcaaa tctgctactt
     7621 ctttttcttt taataattca tgcccacgtt ctagacaact atttatttct tgttcatctt
     7681 ctgtaaaagc tgtcattgtt tcggtaggga tggctttggc tgaatgctta aggatttttt
     7741 tctcttcatc gatggttaaa tggacttcac cgacatactg cccgtacttt ccagcggctg
     7801 ctatttggac atcattgatt acgtgacctt ctctgaataa atgatgggtg tgcgatccta
     7861 aaataacatc aattgctggt atttcttttg caatttggaa atcatcctga atcccgagat
     7921 gactcatcaa aactaaaaca tccacttgtg aacgtaaatc ttcgactaat tctggcaaaa
     7981 tatcataagg attccgtatg tcccagccat tcggattata agtaagcgga aatggagcag
     8041 taaatgcaat tagtccgatt ttcgtctggt gtttcgttgt aatgatttta tatggtttcg
     8101 tccatgccgg tggctggagc gtatttttat cgaataagtt atccaggatg atatcaaact
     8161 cagcatgatc gtataaatga ttcaactctt ctttggaatt tcctacgcct tcattgtttc
     8221 ctatcgtcgc tgcatcataa ccaacttcat tcatcagcaa gatattttcc tgtccattcg
     8281 ttgcttctga caatggatgc caacgatcca caaaatcacc tagatctact gcaatcgttg
     8341 tcgttttttc tttcttttcg ttttctcgtt tacgttgatc caaaaacctt ctgatccttg
     8401 gccaattttc taaatgagaa tgcagatcat tcgtatgtaa aatcactatt ttttccatgt
     8461 accctctcgc ctctctttat ctttatcata ccataggcag ctttttcttc cattgaaaca
     8521 agctctattt cagagttttt cctgccttga agcaaattgt ataagtacaa tattcgataa
     8581 atcagtctgg ctaaaaaatc aggaacattc atttttacag tactataaaa ataaaaaaaa
     8641 cagacccgaa agtctgttgt cgtttcatta taatcagaca catggcggaa cctgcttagt
     8701 gctgcttcct tccagacctg acacgcttca caagcccacc attgtcctag cctttcggca
     8761 aagaatagta taccttattt ttcattcgtt gaccagtctt tttttaattt cttttttcgc
     8821 tggcggagct ttcggaaaaa gtcagtcaaa atcatcccac attcgtcttc taaaatgcca
     8881 ccttctacat atgcttggtg gttaaaccgc tcgtcctcca aaagattcat caaggtaccg
     8941 gctgttccgc cttttggatc atacgcgccg aaataaactt ctgctacacg agacaaaatc
     9001 atcgcgccgc tgcacatagg acaaggctct aaggtaacaa aaagtgcagc atcttccaag
     9061 cgccagcttc ccactttttc acaggcttcc ttgattgcaa gcatttctgc atgtgtagta
     9121 gcatcttgcg tggtttctct aaggttatat cctcttccaa tcacttttcc atccaataca
     9181 accactgctc caatcggaac ttcatgaagc atttctgctt tctttgcttc tgccaatgca
     9241 aggcgcatcc atttttcttt ttctactgca tcaagatttg tatttaccaa ttacccttcc
     9301 ctgcctttgt tttttcttgt tttactttag catatgataa aaaggctgta actaactttt
     9361 tttctatggt aaaataaata caagaggtga acaagatgaa aatggataaa ttacttgctc
     9421 tttacccaca agcacagaaa aaaaactctc cagcatcaga agcggatatc ctttcttttg
     9481 caattgatga tgcttttatc tggatcaaac aagattcatt atctcaacaa gaaaccagcc
     9541 ttttgaaagc gttattccct gtaatcaacg atcaaaaaaa acacccatgg tatcactatc
     9601 tttttaaaga tgcttcttgt gttcaagaaa aaagctttcg tttgatccag cttcacgtcg
     9661 aatcaaaagg agaattctta aaaaaagaat ggcaagatac tattttggaa ttatttcgct
     9721 attctgctga tttctttttt tatacagaca cagatgcgct cttagtcgaa caaataaacc
     9781 gtgattatct tgatgctact gaaatcaacg gtatttttct atctttagat gctgattttg
     9841 atacgacaac gtctgtattc gttggttctt tccattcacc tggcaccgac ctcgtccctt
     9901 tgtttgctga agaaagaaaa atttttttaa cagagcaaaa caatctttat actcacagcc
     9961 gtactttttc tatgcaagat gtggctttac attactatac aaaagatact gtaaaagata
    10021 gtaagttgat caaaagttac atagaactga tcaaacaaaa tgaaatggaa gtgatcattc
    10081 aagaattatg gaatgaatta ggcaatgtca gctctgctgc aaaaacactg tttcttcatc
    10141 gtaatactct aaaatatcga atcgaaaaat ttcaagaaca gtctggtttc aatctaaaaa
    10201 aagccaacga tttactgttt tgctatcttt tattgcttca tgaacataat taaagataga
    10261 ttaaaggggt tgtgacaata attttgtcac aaccccttat ttcgaatgaa tagtgttcaa
    10321 aagctagttt ctcttacatc attttttcaa caaaatgcat tagccggtct tttacatctt
    10381 cggttgaatc tttgattgaa tcaccataaa cagagatttt cttttttcct gatttgattt
    10441 ttgctaacat tcccatcaaa gaatccaagt cactatctga aagaccatct acgatttcta
    10501 gtaatttttc atttccatca aatttgtcat agacgaattt ttttactttc gtccgagtag
    10561 tcatatgatg gatcttttcc attacttttc ccgatacaac gactgctgtc gctacactgg
    10621 cagcggctgc tacgcttaat ccgattgtta cttttgttga tgttttcata agtatcagct
    10681 cctttttatc tatctccatc atagcataga caaaaaaata aacgaactaa tccactcagt
    10741 gaaatctcaa tcctttaggg aaaaagttct ttactgttcc ttttacttgt ttcccaaatc
    10801 cgacaggtat cttatctaat actagcaaaa cccatccttg attcccatca cgttgaaatg
    10861 tttctcctgc tgtgtaagat tgccattcct tttgagtgat cggcaagcaa ggtatattct
    10921 ctatcttttt tgtagcaagc gctaatgcat agctaggttc aaatcgattc tttttgaaat
    10981 ctcctaaatg caaacctgta cgtacgactt ttaaaccatc gagagaaggg gctaactcag
    11041 gaacttccca aagatggtcg ttgaacacta aaagtcttcc agtagcttca taatgaaaat
    11101 catttgaaaa ctccgtccag agtttttcct gctcttttgt catttgcact ttactttttt
    11161 ttcgtgtctt cttttcttta tgcatctgat tttgtccatg aaaagtcagc tttgcaacaa
    11221 aatgtccttc accctgatct ttatgaggcc atatacgtat tgttttttcc aaaccagcta
    11281 cgcttcccca ttcagaacgt cctgaactaa cggattgagt caaaggaatc tcctcaatcg
    11341 ttactggata attttctaca agccagctaa tgatctcttc attttcttct ggtgcaaacg
    11401 tacaagtcga ataaatcagt tgtcctttat tttttagcat ttttattgct gaagacaaaa
    11461 tctcttgctg acgtttttga cagtatagcg gagattcttc tgtccactct tttattgcat
    11521 ttggatcttt tcggaacatt ccttctcctg aacaaggagc atcaaccacg atccgatcaa
    11581 aaaagcccga aaaatgaggg acaagttctg cgggtgcatg atttgtcact attgcgttcg
    11641 aaactcccca tcgttctata ttttctgata aaatcttcgc acgtttcgga aagatctcat
    11701 tcgtcactaa taaccctttc cccttcattt gagcagctaa ttgggttgat ttaccaccgg
    11761 gagccgcaca caaatccaaa actttttcac cgggttttgc tgcagcagct gttccaacga
    11821 tcattgcact tggttcttgg ctatattcat acccagcttg atggaggaaa gactttccat
    11881 tgacagtgcc aagaaatccc tcattgctgt agggagcggg ttgtaattct tcgctatggt
    11941 aagtttggac catgtccaat cctgccggtt ttagtggatt ccaccgaaat ccttttttca
    12001 cgcttccttg ttcaagcgca gaaaaaaaat cggatgcttc ttcgcctaaa agaagacgat
    12061 attttttgat aaattgctgt ggtaacgttg tcgcttcctc cttcattcca atgtttcgtt
    12121 agacatttta caatcttttt tacgaaaaat aaaggtggct gatctacttt ttcatgttgc
    12181 tgcctaaggt gactgttcct ttaagatatt ttccaagtat tcatccgtca cctcgttttt
    12241 atcccaaaca gcgttcatca tttcaagaaa atcttgagaa gaatcatctg agcgcaaact
    12301 tcccaatgca ttaagccata ccaattcaag cgacttttct tctttgatct tcgtgtgacc
    12361 tttgacatat gagaaaaatg gccgcttaaa tagcgaatcc atgtctaaat cagattttgc
    12421 aatgatttca cgaatacttt catggataga aaaaaaatct ttcaataagt agacaatgct
    12481 taaaacatca tcggaactgc attcagctaa gtagttttca aaataaacag tgatttcttc
    12541 taatatcttc tcttttaacc cgctgattga tttgaaatgt gtataaatcg ggtatgtaga
    12601 acaaccgcag aactctgcta actctcttgc agtaattgac ttcattccat attcttccac
    12661 gtataccata cttttgaaca gcaaatattc tttactataa tttgttactc tccccatcat
    12721 tcttacctcc gtctcttttc atctacccat aaataaataa cataaataat tctaaaaata
    12781 ttattgataa ttatcaaaac atatttagtt atatccatta aaaatcaatt tttccgcctt
    12841 aaaaacaaga atatcttgac aaaataccct aggaaataaa caatagaata aacaaggtaa
    12901 caaaaaaatt aaataacgtt atataaaaaa gaaggcgaca ctctgtgaga ataacacaga
    12961 ctgaaatgac tttccactca cagtttttgt ctaactatat acaaaaacag aataaaaagg
    13021 aggtatttat gctaattgaa gcaagaaaaa aagagttact tgttctacaa atggtcattc
    13081 aaaaaaataa ttgttcttta caagaattat ccaatgactt acatattcca aaacggacaa
    13141 tcaaagaact gatccgaaaa ataaatgtat cactcaagca atttttattg attgatgaat
    13201 ttatttattc taatcataaa ggagagatcc aaaccaaaga aaccgatcaa actaaaaagt
    13261 tagctgtttt ttctaagtta aaattatgct acctaaaaga atccaatcgt tttaactatt
    13321 tgatgttact aatcaattat ccacaaactg ctgtaccaaa aaaatattta cttgaacaac
    13381 tttatatatc gccctcctat ctcgaaaaac tgacaaaaca gctcaatcat tccttaataa
    13441 aattccattt acggatccta tctgtaaaaa attgctgtac tcttgaagga aatgagttat
    13501 ctatccgtct ctatctttac ttttttcttt cagatacatt tggaggtaac gattggccat
    13561 tttcctcact tgaattaaat gcactaaaaa tgaacagtac agatgagcaa atagaaaaaa
    13621 tttcaaaaca agaaaaaaat atctacttgc tgttaacttt attcatatta cgaaacaaac
    13681 aacaggcata ttttccaaaa acttcttctg aaatcactga attgatggac ttattgcagc
    13741 atacacatga ttattcagaa tactttactt ctttttcagt gagtcgccct tgtgaagaga
    13801 cagaaacaga gagagcctac tttaattatt ttttctattg tttttttcca aatcaaatct
    13861 cttttcgaca aaaacaggag attggttttt tattttccac aagcaaaaac cttatttgtc
    13921 gacaagtcgg tcaattgatg acttacttaa ctcaacagtt tcctctcaac catttagaaa
    13981 ataaaatacc aatttatttt tattttcttg tgttggcagt tgtttttttc gaactgttgg
    14041 gtgaatccag cagtagtttt tctacacttt gctttccaga agccacgtcc aatcattcta
    14101 gttcttttat acaggaaaag aaattaagag aaaaaatcga tacaattttt tcaaaaaatg
    14161 gggaaagaaa ccaaatcagt caatacctta gtcaattgat ccaacactta ctacaaacag
    14221 aaacgaaaga gcagttactc atccatttgc agataaccaa acagtttaca ggaaattatc
    14281 atcttcaaag ccatttgcag cagttatttc gcaaagatgc tgttaaaatt accgcatatt
    14341 cagaacatgc tgatttgatc attacagatc agcatgagaa aatttcagat gaaacggaga
    14401 ctttctatct ggatacaacg cacaatacag tgttatttgg caagttaata aaagcggttc
    14461 atgaactgta tatgaaaaaa ggttatgaga acaaaacaaa gaggatgtga caaaattctt
    14521 gtcacatcct cttattccaa ataaatggta ttcaatcagc taactctcgg tattagctca
    14581 gatcaaagcg ctgatttcac aacttcttta ttttaatctc ttcggttgcc gccgaacaat
    14641 aagatcaagc gcaacagctg caggaatgtc gaaagcgctg ctgcaacata agtcagtgct
    14701 gctgcaaata atacgtgtct tgccatcggt acttcttctt ccgtcagtag tccgccttca
    14761 ctcaaaattt ggattgctcg ccgagacgcg ttaaattcga ctggtaatgt caccaattgg
    14821 aaaagtaatg ctaaagaaaa agcgaaaatc ccgatattga ttaacgtaga gttccagcta
    14881 agcaatacac ctaccataat caaggggaac gaaatcatcg aaccaaagtt agctgctgga
    14941 acaagtgctg cacgaatctt caatgggaca taacccgaag catcttgtac cgcatgtccg
    15001 cattcatgag ctgctacacc tatcgcagca actgaagtag actgtgcagt tgcttgagac
    15061 aaactcaaca tcttattacc tgaattgtag ttatctgtga gatctccggc aatttgttga
    15121 acaccgacat tatttatctg ttgactttgt aatatatatt gtgctgcttg tgtaccagtc
    15181 acattgtttt tgcttctcac ttgatcgtat tttcggaaag tactattgac gtacgctgac
    15241 gcaattccgg aaataactaa tccaagaatg accaaaagaa atgtcggatc taaaaaacca
    15301 tacattccat aaccatacat tttcgtttca ctccttttcg tttactttat tttatcatta
    15361 gtagtaggaa aagaatgtga aaagaccttg aatattcttt aattcttttt cacaaattcc
    15421 gatttcagtt tcatcggtcc aaatccttct accttgcaat cgatattatg atcgccttct
    15481 actaaacgga tgttcttgac ttttgttcct tgtttaatgg cacctgacgc accttttact
    15541 ttcaagtctt taatcactgt cacgctatcg ccctctaaca gacggtttcc atttgcatct
    15601 aataccacta atccgtcttc tatgacagtt tcttgttctt ctttgttcca ttcgttcccg
    15661 cattctgggc aaatcaacaa gcctcgatct tcatatgtgt actctgagcc acattctggg
    15721 caatttggta atgtcatctt ctttctcctt taaaatcttt agtgagcact attgtaacgg
    15781 aaaaagaaga tcttgaaaag atacatttgt gatttttact acaaaaggca cgttttcgaa
    15841 cgaagtatca ttctgttttt ctgctcttat acgattggca tatatcttgg atctctttat
    15901 agatttcctc tacttctgct aaatcttttg cattcgcacc acttgctaat ggatggcctc
    15961 ctccatgatg gcgtttagcc aattcattga tgatcggccc cttagaacgt aaacgtacgc
    16021 ggtaataccc tgaaggctgc tgaacaaaaa tcccccaagc cagcacttcg tcaatcactc
    16081 caggaagtga aacgatcgaa gctgtctctg aatcatcgat tccatattta tcaagaattt
    16141 cttgcggaag gattattctt cctgcaccat tttcatccac ctggatattt tgataaagat
    16201 aaccggaaag tttagcgact ttcatcggca tttgttcaat ctctctgttc aaagcacttg
    16261 catcaaatgg ataatttctc aatatcgaag caatctctaa tgtacgggac gtcgtggagg
    16321 gatacaaaaa gcgccctgta tctccgacga ttcctgcata aagtaaccgt gcagccttaa
    16381 cgttcatctt taaagattca ggaaacatca aagcaaattc tgcaatcatc tcactacagc
    16441 tacttgcttt tgtatttacc cacacaagat ctccataagg gtcatcattg ggatgatggt
    16501 cgattttgat cagtttttct gccaactgat atctttgatc actgattctg ggtgaattag
    16561 ctgtatcagt cacgatgact agcgctcctt ggtagaagac atcttcaact tcttgcattt
    16621 ctgctaaaaa gcgaagccct tcaatcgttt cacctacttg acgtatttct ttttctggga
    16681 aactttcccg taatagttcg gctaatccta cttgtgatcc taatgcatca ggatcagggc
    16741 gcaaatgcct gtggataatg attttatcgt atttttttat tgtatctact atttcttgct
    16801 gtactgtcat ttcactcctg ctttctaaga acgttccatt acttgacaaa caacgattgc
    16861 tttggaaacg atggtgtttt caataaacac ttcgatatcc agtttagcgg aacgtctgcc
    16921 gatttccaat acacgtggac gaatgtctaa ttcgctttcc aattggatca gccgcaaata
    16981 atgtaggttc acttgttcaa tcaagatatt tcgtttttgg ttcatcacca ttgttttttg
    17041 tgcgacatca gaaatgattt cgctaagtac gccaaaagaa atggttccaa cgccattgac
    17101 catttgtggt gctactacga atttgaactt agggttttcc aaacgatttc cttcacggtc
    17161 agtatcaatc gtatggatat ttccagatat ctgatccgaa atcgtatctg caatctgcgg
    17221 ttgtcgctgg acaagctgca tcgctttcat tacatcttgc cgggtaatca agccttccaa
    17281 tgtcaagtca tcggaaacga ccggcatgac ttctagccca tcccagatca tttgatggct
    17341 aacagaggca atactcattg ttttctttac actgattggt tctttcgtca tcacccgatc
    17401 gatgatctgg tttggcgatt tccctaaaac atcttttgcc gtaacaatcc ccatcaaacg
    17461 atgatggcgg ttgacgactg gaaaacgcga atgctgcgtt tcttctgaca aacgctgata
    17521 atcagaaatc gtatctgtct gctgcaaata atgagtcttt tcagctggca tatagatatc
    17581 actgacaagc atgatatctt ttttgatcaa ttggtcgctt aacgctcggt tgatcatggt
    17641 tgcgactgta aatgtatcat aagaggtgcg taagatcggc atttcaagat catcagctag
    17701 ctttgcaatc tcagcagtcg tattgaatcc tcctgtgatc aatactgcgg cgccatcttc
    17761 caatgctaat ttttggactt ccgcccggtt gccgacgatc attagtgatc ctggcgtaat
    17821 atagcgttcc atggcatgtt tagtcatcgc gccgatgacg aatttattca agaccttgtc
    17881 taatcctgcc gccccgccta aaacgtcccc ttcaatgatc ctgacgacct cgccaaatgt
    17941 caaacgttca atatgttttt ttaatttgcg ttcgatacgg atggtcccta ctcgttgaat
    18001 tgttgaaact agtccgacat tttctgcatc tttgattgca cggtacgctg ttccttcact
    18061 gacattcaat tcttttgcga tgcttcttac agaaattcga ttgccaacag gtaaactttc
    18121 aatatattct aaaatcaaat catgttttgt cgccattttc tgcctacact tccagcgttt
    18181 ccgagacgct cattattttt ccttcactat cttccagtaa ctctacaaaa gattcgggat
    18241 cttgttcaat gacagggaaa gtattgtaat ggattggaac tactttcttg gcacgaattg
    18301 tttgcgcagc ctttgctgca tcttctggcc ccatcgtata gttatcgcca atcggcaaga
    18361 aagcgacatc aatatcgaat tcttctgcaa gcaatcctag atcactgaaa taagcagtat
    18421 cccctgcatg ataaatcgtt tttccttctg cttgaataat aattccgcta ggctcgccca
    18481 tatactgaac gataccgtct acttcatagc ttgaactatg ctgtgcatgt acgaatttta
    18541 ccacgccgaa tggaaacgca tgttttccac cgatattcat accgaatgaa tctactcctc
    18601 tgctgttcgc ataatcagca atctcaacaa tactgataat tgtggcttga ttttcttttg
    18661 caataggaat catatctcct atgtggtcac tatgaccatg agtaatcagc aaccaatctg
    18721 tctttacttc ttctgcagtt aagtctgtca atggatttcc tgtaataaac gggtcaatca
    18781 tcacgcgttg gccattttcc atttcaattg ttaaacagga atgtccatga tacgtaattt
    18841 tcatatttta cacctcgcgt tttctctgta tcttttttat taaaaacgat ttcatcactt
    18901 gcacatcaat gaaaaaatat agctgctaaa tatattttca ttggattgat agtacagtat
    18961 gtacaaagca attgtaacag ataatacagg atgcaccaag taccaagcag atataatctc
    19021 aagtttgagg tctctgctct gcttagcttc tcttctcgtc ccttaactaa ttaaatcagc
    19081 gtaaatagga tggacgatct tttctaaatc ggctactttt atccgaaggc ttctcccgat
    19141 ttcaccgctt gacacaatta cttcttcttt ttcttttaaa gaactgtctg ctaaaaaaca
    19201 ataatcagga tgtgcgagtt ttattccaat aggggtgttt gctccgtggg gatatcctgt
    19261 atgcattaat acaaaatcca ttccaggaaa accaacttta cgatctttcg tcacttgtct
    19321 cgtttttttg taatctaagt gatcgttcaa aggaatcaat gcgatgatca ccccagtttt
    19381 gtttcctttc actacgagag ttttacatat caaagctgga tcaatccctc ttttttgtag
    19441 ttcttctgtg aaagattctt ctaccacatg actaaaatca agtggttgat agctgatctt
    19501 ttgttcttct aaataacgtt cgacttttgt ttgactcatc attgattcac tccctttatt
    19561 ctatcgttta ttataaagcg agggatgctg tattcaaaaa ttatttgttt ttcgcaaaaa
    19621 aagagcaaga cgagcactct atagagaggt tcatcttact ctttttgttt attttttatt
    19681 tcgacgttga gtagcttcca taatgactgg caagatcact gggcggcgtt ttgtttgttc
    19741 aaataagtaa cggcctaatt gatctcggat gtcttgcttt aatttgctcc actcaaaatc
    19801 attgctttct aaatgtttct caacgattgt ttcaatcata ttgctgcttt ctttcatcag
    19861 atcacggcta gcttttacgt aaacgaatcc ccgtgaagta atttgaggtt ttgaaatgat
    19921 tttcttttct cgccgactga tagtgacaac cgctacgaaa atcccgtctt ctgacaagat
    19981 ttttcgatca cgtaaaacaa tgtttccgat atcacctatg cctaatccat caatcattac
    20041 attttctgca cttgtagttc ctgcaacact catacgcttg ttcttatatt ccagcacgtc
    20101 tccgcgtcca gtaatataga tatttttgta tggcatccct actgcatgag ccaaatctgc
    20161 atgagcagct aattcacgat actctccttg aactggcaca aaatatgttg gtttcatcaa
    20221 attgatcatt aattgcaagt cattaggatt ggcatggcca gaaacgcgca tattctcaga
    20281 gatcaacttc actgttccac cagctcgata aatgatatct tccgttttcg ccacgatggt
    20341 ttccatcgcg atgcttggcg tagtagtgat ataaaccaaa tctccttctt caatcttgac
    20401 attacggtgt gtaccgtttg ccattttttg cagagacttg atgggttcac ccattcggcc
    20461 agtttctaaa atgatcagtt cttctggatc atagtttttc atgtctttca acgtaacaag
    20521 cagatcttca cttggtaatt gaagtttttc taaacgcatc gctgtgcgaa taattcgttc
    20581 gaaatcttga ccagtcaaga caacttttcg ttgtgctttt tctgctgcat ccaatacttg
    20641 ttgcactcgt tgcaaattac ttgctacaca agcgacgatg atacgccctt cccaatattt
    20701 gatcgtatca aatacttcat ctgctatttg ggcttcagaa gctacaggct gaggattttc
    20761 tgcatttgcc gattcactta gtaaggctaa gactccttct ttgccgattt ccgccaatcg
    20821 tgcataatct gtttgataca ttgggatagc cgtttggtca aatttaaaat ctcccgtata
    20881 aacgatacta ccttcttttg ttttcagatt gatccccact gaatctggta tcgtatgagt
    20941 ggtacggaaa aagctcacta ctgtttcacc aaagtctatt tctgtatgct catctaccac
    21001 atggaaatcc ttaaatcctt tggctgcttc attacgactg acattcaatt ttgctaactc
    21061 gatcgtcaac tctgtcccga atactggtac agaaattttt gacaacaagt aaggaagtgc
    21121 cccgatcgca tctgcatgtc catgtgttaa aaagacacca gctacacgat caatgttttc
    21181 ttctaaatac gtaaaatcag ggattacgac gtcgatcccc aacaactcat tttcaggata
    21241 ttttagccca caatctaaaa taaaaatatc ctcgcccact tctgcgacat acatgttttt
    21301 tccattttca cgaacgccgc ctaatgggat aattttaatg gtactcacaa acttcacctc
    21361 ttcttatgac atccaagttt aaagatgtcg attttcttct ttatctaaat atatgagcca
    21421 ttccaatgaa gcatatgcaa aatcactatt tctcaactta tggagaatca gcaggaaaat
    21481 taccagcaca tccgcgttct gacagttgga tgggcatttt attttggata tacttcatta
    21541 acaaaatgga tcttttgcga aacgctatag ccagaatact tatataagta ttcagctgtt
    21601 ccccattatt atacaacaaa taaactaaat cgctagtatc agcaattgtt agaacaacta
    21661 tgcacgtaaa aatccctctg tagcatctag gatttctttt gctattcctc tttcatttct
    21721 tcttcgtcgg tttgaaacat acttttttca ttttaccaca ttttttgcaa taactatagt
    21781 gactttttat atatacagaa cctcatgttg atggtgtgca aacagcataa gatttaagct
    21841 agctttaaga taggttgtct attatcaaat gcatctacta ggagggatgc aaaatatgaa
    21901 ttttatgaaa cgtgcatgga aaagtacaaa agtaaaatgg ggacgttcat tgttattgtt
    21961 tgccgtgttc acagccattc ttatttttgt gctagctggc ctcacgattc gaagcgctgc
    22021 agaagaagca gcgaatcaag cacaaaaaga agttggagca acagtgactt taagtgccaa
    22081 tcgagaagct tcatttaaaa aacaggaaca aacttcttca agcggttcta ccactgaaga
    22141 acgtccagat ccaggcagtt tttctcttac accagtttcc ttaacggacg cggaaaaaat
    22201 agctgaatta gataatgtaa agagttattc ctttgaaagt tccgcctcag ctatggcaaa
    22261 agatggaata actgccatca ctagttctga ttcaagtgaa gacagttcag aaactactga
    22321 tgcaggcggt gaacctgctg gaggaatggg cgggaatccg caaatgactc aagcagactt
    22381 tcaaatcagt ggtgtgtcag caactgcaca aaatagtaat ttttctgatg gaacagcaaa
    22441 aatcacggat ggtgaaggaa tagatgacag cgacaaaggc acaaacaatg tagtcattga
    22501 ttctactcta gcagaaacaa atgacctggc agtcggagat actttcacaa tcacgagtac
    22561 tgaagatgaa gataccactt atgaaatgac gatcaaagga atttatgaat ccagcgaaac
    22621 aagcggcagt atgggtatga aattcaactt catgaatccg tcgaatacac tttacacttc
    22681 ttacactttt gcaaatgaac taaatgggac atctgacgat aacacgatag attctgctat
    22741 ttacactcta tctgatccag ataaaatgga tgagtttctc aaagaagctg agaagctgat
    22801 cgacacagat acatttagct tacaatcaaa tgattccatg tatcagtcaa tgttggaacc
    22861 tttaaacaac gtggcaagtt tttctaaaaa tgttgtttta ctagtggctg tagccggtat
    22921 tatcatactt actctgatca ttatgattac cattcgggag cgtcggcatg agttaggcgt
    22981 cttgctatct ttaggagaat ccagaagtaa aatcattctc caattgttta ccgaagtggc
    23041 tatttgtatg attcttgcat taggagttgc ttcgcttagc ggaaacgtcg tcgcgaatgc
    23101 cgtgggacag cagctacttg accaacagac agaaaccacg acacaaaacc agcaagctcc
    23161 tggcggtgga caaatgccag gtaacagaca agaacaaggc ggtcaacgcg atggtcaaca
    23221 aggaaccacg aataatccat ttgctgtttc tgatcaagtc agcgaattgg aaatcaatgt
    23281 caaacctgca caattgggac tattagccgg agtagcattt ggaatcagtc tgttttctgt
    23341 ctttttagct tctataggga tattaagatt aaacccaaga aaaatcctat taaactaaag
    23401 gaggaatttg atgttacgga cagaacaatt gggattttgg tatcaagatc cgcaagatgc
    23461 gctttataaa gatgtagaac tgaatttcga agctggaaaa atgtacgcta ttttaggagc
    23521 aagtggttct ggaaaaacga cttttctttc gcttatttct ggactagatg caccaaaaga
    23581 aggaaaggta tactatcaag atcgttcact gaacaaaatc gggttaagaa gttatcgtaa
    23641 aaatgatgtc tcgattattt tccaagctta caacttgctt ccttatttat cggctctaga
    23701 caacgtcata gcagcaatgg aaatcactaa gaccaagcaa gagaattatc gacaagttgc
    23761 tttagatcga ctggctcgtg taggaattga tgaaatatta gcaaaaaaac aggtgaccaa
    23821 actttcggga ggtcagcagc agcgagtcgc tatcgttcgt gctatctgct gtgaacatca
    23881 actaatcgta gcggatgagc ctactggaaa tctagatgaa acaacttcac aagatatcgt
    23941 caaacttttc caagaaatcg cccatgaaca aaatcgctgt attatcatcg tgactcatga
    24001 gattgaagta gcaaaaagct gtgatgaagt ctttgaacta aaaaataaaa aatttcaaaa
    24061 aatcgaagtt taaaaaacag gataatgatc aaataaaaaa tccgaaccat atctgtctcg
    24121 cagatatggt tcggattttt tatttgcttg attcaattag taataagtgg tttttatttt
    24181 ttttcgtctt ttcgagaaaa cttgtctttg acttcgtcgc ctaaatttcg agctttttct
    24241 ttgatgtcag cacctagtga ttgtgctttc ccttctgttt ctttgctctt gtcgtctgtt
    24301 gctttgccgt atgcttcttt tccttcaccg actactttat ctttcatatc tttagaacgt
    24361 ccttttaaat ctgccattgt gcttcctcct cttagtttgt ttattgatct accttcaggg
    24421 taacatcaac aacagataca gacaaacaga acgctcgttt tctaaaaaag atagttagag
    24481 ctgttgatta aaaacttttt tcgaaagtcc cccatacttt gacttctttt tcttggacca
    24541 ttatttctcc tttagcgata actgtatcaa tatcaagcgt ttctttatcc aagatacaca
    24601 gatctgcatc agcaccaatt tcgatttttc cttttttatc caatttcaat atacgtgctg
    24661 gattactggt tatagctcgt aaggcgattt ccaaagggat actttctttt tgcacagctt
    24721 ctttgatccc tactagcaat gccttggcac ttcctactcc taaccctagg aaatgattgt
    24781 tttcatcaaa ataaggcaag cttccttgtc catctgaggt catcgtgaaa ttatctaaag
    24841 aaacatcttc ctcgatcaat cgtttcagtg ctttgctgaa gcgaacttca ccatctgtct
    24901 tctcccaaaa atcaggatct tcgctagcag tgaagtcaat cgtgccacca cgtttggcaa
    24961 atgccacgca agcttcaaat aattctggtg tgcgatttgc atgagtaggc aaaaattgtg
    25021 tgatcggaat ttctgtttct tctacgattc gtgtcaatag ctctagcttt ctttttcctc
    25081 cgcctaagtg gacattgatg atcccagctt ttccggataa catgcctcct acacgagcat
    25141 ctgctactgc acgagcgaac tcttcaaaac ttggctgaga agaacggtga tcggatactg
    25201 cgatttctcc gattccgata attttatcaa ttgtcaaaaa gtctttgatg atagaatctg
    25261 ttactgtttt taccggcaat cggtacgaac cttcgtatac ataagtggag attccttctg
    25321 cttccagacc tttcgctttg ctgatcaacg cagtcatatc tctaccttct ccgtctgttc
    25381 ccaaacaacc gacaactgtc gttacaccag ctgtagtcaa ttggctcaat gtgacttctg
    25441 gcgttcgatt ttgataaccg ccttctcctc ctccacctaa aatatggaaa tgacagtcaa
    25501 tgaaacccgg ggttagtact tttccctcac ctgaaagttc ttctacttcc actccttcgt
    25561 agccgccttc tagctgttct tctacagcca aaatcttccc accggcaatc agtacatcca
    25621 tttttcctaa gtaatctggt gcaaacactt caatttgtcg aatgattttc atacattttt
    25681 cctctttctt taagtataac tgatgatagg atcttaaaaa ataatccaaa cgataggatc
    25741 tttactcctt tgattttacc gtaaaatgac ggttcttgga gtccttatct actgtttgga
    25801 ttactttttt atttacaggt ctccagtact actgcagacc tattgcaatg gcaatcatga
    25861 tgaaaatagt tcctaaaaca aacaggaatc cttgcatctt gatttggaat cttgcccatt
    25921 ttgcccattc gatccgtgca acacctagca caccaatcaa gctggctgat acgggtgtaa
    25981 aagcgtccat aaaacctgaa ccaagctgat aagcaagaac tgctacttgt ctggatacac
    26041 ctactaaatc tgccagtgga gccatgattg gcatagtcaa agctgcttgt cctgaatttg
    26101 atgtaacaac caagttgaac aaactttgga agatgtacat cgcccaagca ccaatgacag
    26161 ctggaacacc ggtcaacgcc gtcccgatcc catgcaaaat cgtattcaaa gctgaaggaa
    26221 cagatgcatc agatcctccc aagacaagaa gaatcccttt ggccatacct actacgattg
    26281 ctgtaccagc taaatcagct gcaccagatt ggaaagaaga agcgatgtca ttgactttca
    26341 ttccatctaa tttgaaaaga acagcaatga ttccagcaac taatcccatc acaaagaatt
    26401 gagaagcgat ttctggaatg taatagcctt tttgagtcac gccccaaacg atccagacaa
    26461 ggacaactaa catctctaat aagatcaatt tatgcccaag catgaatttt ttattttcat
    26521 cagatgtctt tttgatatga gaacggaaat aatcatctga tttgtaagtc aacgaacttt
    26581 ctggtttttt acggattttt tctgcatata tcatcatata accagcggct aatgcagtaa
    26641 caactaccca cataatcaat cggaatgtcg caccagacaa cacggggatt ccagcaatcc
    26701 cttgagccac cgctacgcta aacgggctca tccaagaggt cgcatttccg acttgagatg
    26761 cgacataagt cacggttact gctacgatcg agtcatatcc taacgcaatg acaaatggaa
    26821 ccatcaccat tgagaatgga attacctctt ctgccatccc gaatgtagcg ccaccgaatg
    26881 aaaaagcaaa gaataatagc ggtaaagcta aacgctccag tcccttagtt ttactgataa
    26941 acgcatagat acctgcgtcg atcgctccgg tacgcataat aataccaaaa gcacctccaa
    27001 caacaaggat caatgcagcg atccctacag cagatccata cttatctcca gatactagtc
    27061 cttcaaaaac aaaatttaag aaaccaaagc cgccaaaatc atctgttccc catattttgg
    27121 ctgttttatg caatttttta gaagtatcat agatattttc gccgtactga tcgtaaagca
    27181 catcatctgt caaggagatt tcatctagtt tttcctgcgt aagatttttt tctccgtcag
    27241 caatgacttt ttccaatcct ttttccggaa catccagttt ttcacgttct gctggatgat
    27301 cttgcagttc ttctaattga tcaaacacat acgacttatc cagctcgtaa gcataacgga
    27361 aggaatcttg acgtaaaaca gtacgagtac ttgtttcgcc atttgcatct ttgtattcaa
    27421 tatcttgcgt gctgaacttt cctgctggaa cgacaaaagt cagtatccat gcaaagatga
    27481 ctacaccaaa aataatgaca tacgtatggg gtgtcgataa tttagtgaag tcgcgtttcg
    27541 gttttcctga agaatttgtt ttcttcaaat ttatttcttc ctttcttttt tcagtaattt
    27601 tgatgaataa aaaatggata atcaaatgaa ttatacagta aaaatg
//
LOCUS       DAFLWZ010000033        26657 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000033 DAFLWZ010000000
VERSION     DAFLWZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.033"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1301)
                     /locus_tag="L1V38_001487"
     CDS             complement(<1..1301)
                     /locus_tag="L1V38_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316040.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFL"
     gene            complement(1312..1980)
                     /locus_tag="L1V38_001488"
     CDS             complement(1312..1980)
                     /locus_tag="L1V38_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1316041.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2110..2694)
                     /locus_tag="L1V38_001489"
     CDS             complement(2110..2694)
                     /locus_tag="L1V38_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1316042.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(3025..3258)
                     /locus_tag="L1V38_001490"
     CDS             complement(3025..3258)
                     /locus_tag="L1V38_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBN1316043.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(3273..4223)
                     /locus_tag="L1V38_001491"
     CDS             complement(3273..4223)
                     /locus_tag="L1V38_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1316044.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(4220..5062)
                     /locus_tag="L1V38_001492"
     CDS             complement(4220..5062)
                     /locus_tag="L1V38_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1316045.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(5064..5783)
                     /locus_tag="L1V38_001493"
     CDS             complement(5064..5783)
                     /locus_tag="L1V38_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1316046.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            6475..6633
                     /locus_tag="L1V38_001494"
     CDS             6475..6633
                     /locus_tag="L1V38_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316047.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            6705..7931
                     /locus_tag="L1V38_001495"
     CDS             6705..7931
                     /locus_tag="L1V38_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1316048.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(8019..8411)
                     /gene="rpsI"
                     /locus_tag="L1V38_001496"
     CDS             complement(8019..8411)
                     /gene="rpsI"
                     /locus_tag="L1V38_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1316049.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(8427..8870)
                     /gene="rplM"
                     /locus_tag="L1V38_001497"
     CDS             complement(8427..8870)
                     /gene="rplM"
                     /locus_tag="L1V38_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBN1316050.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(9389..9856)
                     /locus_tag="L1V38_001498"
     CDS             complement(9389..9856)
                     /locus_tag="L1V38_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBN1316051.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(9976..11514)
                     /locus_tag="L1V38_001499"
     CDS             complement(9976..11514)
                     /locus_tag="L1V38_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBN1316052.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            11594..12280
                     /locus_tag="L1V38_001500"
     CDS             11594..12280
                     /locus_tag="L1V38_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBN1316053.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(12481..13008)
                     /gene="msrA"
                     /locus_tag="L1V38_001501"
     CDS             complement(12481..13008)
                     /gene="msrA"
                     /locus_tag="L1V38_001501"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1316054.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(13092..13769)
                     /gene="pgmB"
                     /locus_tag="L1V38_001502"
     CDS             complement(13092..13769)
                     /gene="pgmB"
                     /locus_tag="L1V38_001502"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1316055.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(13766..14896)
                     /locus_tag="L1V38_001503"
     CDS             complement(13766..14896)
                     /locus_tag="L1V38_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1316056.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(14896..17079)
                     /locus_tag="L1V38_001504"
     CDS             complement(14896..17079)
                     /locus_tag="L1V38_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1316057.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(17076..18101)
                     /locus_tag="L1V38_001505"
     CDS             complement(17076..18101)
                     /locus_tag="L1V38_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1316058.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(18146..18973)
                     /locus_tag="L1V38_001506"
     CDS             complement(18146..18973)
                     /locus_tag="L1V38_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1316059.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(18970..20037)
                     /locus_tag="L1V38_001507"
     CDS             complement(18970..20037)
                     /locus_tag="L1V38_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBN1316060.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(20063..20899)
                     /locus_tag="L1V38_001508"
     CDS             complement(20063..20899)
                     /locus_tag="L1V38_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1316061.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(20896..21765)
                     /locus_tag="L1V38_001509"
     CDS             complement(20896..21765)
                     /locus_tag="L1V38_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1316062.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(21835..23118)
                     /locus_tag="L1V38_001510"
     CDS             complement(21835..23118)
                     /locus_tag="L1V38_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1316063.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(23132..24817)
                     /locus_tag="L1V38_001511"
     CDS             complement(23132..24817)
                     /locus_tag="L1V38_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBN1316064.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            25092..26117
                     /locus_tag="L1V38_001512"
     CDS             25092..26117
                     /locus_tag="L1V38_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1316065.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT         7997 a         5381 c         4453 g         8826 t
ORIGIN      
        1 taaagaaatt ccggatcatg agtagctata actactgcac ccttttcttt taagtcttta
       61 ataaggtcag caatcctttc catattaata taatccaacc cacttgtagg ttcatcaaat
      121 agaaataaat tagtttttga caatgaagct atagaaacca ataatctttg tttttctcca
      181 ccggataaat caaacggtaa ttgatctttc attttataaa gttccatttt ttttaaaatt
      241 ttttcttgct gatctttact aactatttca ttccccaggg ctaactcgct cctcactgat
      301 tctgtgaaaa attggtaatc catttcttgc attactaaaa acggcgatga caaatttttt
      361 ttattttcga ttatctttcc tttggtaggg cgaataatct tcatgagtat tcttagtaag
      421 gttgttttcc ccacaccgtt tttccctacc aaaccaataa catctccaac tttgacatca
      481 aaatttatgt cttttagaat attttcataa gtaatttctt caacttttaa tacatctgca
      541 cttacctttt cgatataggg aacttcaatc gaactattaa aaatgtcaaa tttccttaat
      601 gcgttattgt tttcagtttt taacaactga atagttgtag tttttacagt tctattttta
      661 acaaatagaa cttgatcaat taattctttc aaatagtaaa aacgatgttc agctataaca
      721 atagtaaatc ctttattttt taaatcacaa agtaagtcag caagtttctt agtcgctttg
      781 aagtccaaat ttgaagacgg ttcatccaat ataattaatt tagagtttag cgataaacta
      841 catccaatag aaattttctg ccgttcacca cttgatagcg aaaaaatgtt tttatctaat
      901 atatttgaaa gatctaataa ttcagctaat tcattgattc ttttatccat atgctctttt
      961 gtaaatccaa agttttccat cgaaaatact aactcactcg ttgtatttgt tgtaaagaat
     1021 tgtcctctag gatcttgact tacgtagcca atattttttg atatactttc ttgtgttaag
     1081 gattgtagcg agttattttc aaataaaatt tccccaacca attttccgtc ataaagtctt
     1141 ggaataagtc cattcattaa ctttaatagt gtggatttcc cactcccaga agaaccagta
     1201 atcaatgtaa gactgccttt ttttattgaa aaattaaggt caacaagcgc ttgttcctta
     1261 acatccttat atgaaaaaga aacattgtta aattcaaaca attctttcac ctcaaatcaa
     1321 aatacttaag aaaaaaatag taacggaaaa caggatgata tagtctaata agctcatgtt
     1381 tgttttatag taagaacttc ttttcacagg agattctatc ccctttgtta ttgcattagc
     1441 ggtcatttct tcagcaatca tagttgcacg tataagaacg ggaactaaca gaaattccaa
     1501 atattgcaga ggctgaaaaa aagacaagcg aatgtttctc atttttaaag attctttaat
     1561 cattcttatt tcagaacgat aagtcggaaa gaatctgatc actactgtaa tacttaacat
     1621 tatttttttc ggtaaatgta ttttttctaa agaggataat aattcattgc tagtatagac
     1681 actaaccaac aaccatgaga tcattacgac cggcaacatt cgaaatacaa tatataagga
     1741 tgtcgcaaaa aatatagtaa aaaactctat cttgatagca tcaataattt tcattactaa
     1801 aaacagaact gaataaatca agatgaaata aatacatgtc tttattttac gaaacatcaa
     1861 tactaaaact gtagcaataa tgaaacaccc cacttgaaat atatttccct ttcctaaaaa
     1921 aataatgacc ggaaaaaaaa tatttaaagt aatcaaggtt aacggattga tttttgacac
     1981 tctttcacct ccaaaaaata agatcgcact gttatcttaa gctgataaaa atgcaccgtt
     2041 attcagataa cagtgcgatc ttatcaaaaa gcataactga gaacaattct caatgcaagc
     2101 tttttttaat taactcagta attcaatcca cccaggaaca gaaaattgat acaatcttct
     2161 ggttaatagc atagtctttt cttttgaata gctatgcttc aatatatcat agaatgtagc
     2221 gtagaatgag taaatgtaga agtggatttc ttcttcatta aagactaaat tttgattgat
     2281 cattccgata gtctttaact tatctagaca acagactgtc tttttcgtca caaatgatgt
     2341 aattttttca acaatatctt gatatttggt tccagctgat tggaataaaa tcaaatcgaa
     2401 tatacgttta ttctcaaaaa tataattaat aaatggatct aattcattga agttctctct
     2461 ccaacttttc tctatatcta tattttctaa gtttaagagg tatttggtaa actcttcatt
     2521 atacatatta ataagcgcat taatatgcgg ctgaataatt tcttcaaata acgcttcctt
     2581 agaagtaaaa tgtttataaa aagcacccgt agttacgcct gcggtcaggc acagttgcct
     2641 tatcttagtt tgctgaaatc cttctttttc aaaatggctt agtccacttt ctattaactt
     2701 ttggtgagtt ataatataat ctctggtttc tatgggtact tcctcctaat aagatgaatt
     2761 aactttatta tcttacacag gacttgaagt ttcaatcgtt aacgtttatt actgaactca
     2821 ttccttagag ctaaactaat gagaaagagc agaataactg atacaaaaag caatcctaca
     2881 agaattaata gactcatcta aatcattcac cttttctaaa ataatccgag aaagatttaa
     2941 aaaaattata tccagctatt aggataagtc ctatcataat cactccaata gccattttct
     3001 tatcctccct aaaaataaag tcttttactt aaaacctttt ttgtaatcgt caataaattt
     3061 tttcccttta tcagttaatt gaaatcctat atctaaatag tcctcatatc taagtttagc
     3121 cagcatctca cttacagatg ctggactaac acttagaact tttgctaaat cattattttt
     3181 taatttcttt tttctttttg ataattcctg aattgctagt aaataaatta gtatagtagt
     3241 cgttttaatt tgtaccatac ctaccctcca aattatttcg aaaggccttc agcaatttta
     3301 tccaggttcc atttcatcat cgcatagtaa ctatcaccat cttgtccttt ttctgcaatt
     3361 gaatcagtaa aaatcgttga atagatagga atattggtat cttttgatac tgttttcatt
     3421 ggtctatcat ccacactgct ttctacgaat aaggagggaa cttttgttgt gcgtaatttt
     3481 tcaactaagt gttttatttg atctggtgtt ccttcttctt cagtgttgat ttcccaaatg
     3541 taagcagaag gcacattata cgctttcgag aaatatttaa agcatccttc acttgtaaca
     3601 atcatttttt tatcattcgg aattgaagca aatttagatt tagcttcttt gtctagagaa
     3661 tccaattttt caatatactt atctagattt tctttataga attttttatt atcaggatct
     3721 ttttccgcta actgtttttc aatattttta gcgtaaataa taccgttttc taaatttaac
     3781 caagcatgag gatcttcctt ccctttctca ctctgaccct ctaagtaaat aacatctatg
     3841 ccatcacttg ctgcaaaata gtctttgttt tcctctttgt tcgcattttt aactaatttt
     3901 gtaaaccaag catttcctcc agtttccaag ttaacaccgt tataaaaaat caaatctgct
     3961 tttgaagttt tttgaacatc ttcaggcaaa ggttcatatt cgtggggatc tttcccaata
     4021 ggtacgatac tgtgtaaatc aattttatct tttgctatat tttcggtaat atctgctaaa
     4081 atcgaattag taactactac ttttaatttt tcgttcgaag ccactttatc tttgtcttta
     4141 ctatttattg aacatgcccc gaatataaaa agagcaatca aaatccccag acttcccagt
     4201 actgctttcc attttctcat cataacgatc tctccttctt tcttaaaaat ttttgttttg
     4261 gtgagattag aaaactaatt acaaataaga atgccgctgt taaaacaata cttgatcctg
     4321 ctgctatgtt aaaactataa ccaataaaca atccaagcaa tgatgaactt gctccgactg
     4381 ttgcagaaat aaatatcata gttttcaagc tatttgcata taaatatgct gtagctgctg
     4441 gtgtaattaa cattgcaaca attaatatag ttcccacact ttgcatagct gttactgcta
     4501 ctaaagttaa tagaaccatc aatagataat gataaaaact gacattcatc cctattgctt
     4561 ttgccattaa tggatcaaaa gaagtgatta ataattcttt aaaaaataga actactataa
     4621 ccaacactaa aaccgaaacg ccaattgtaa tccacttatc aatatcttgt acagctaaaa
     4681 tatttccaaa taaaatatga aataaatccg ttgagctatt tgcaactcct ataaggataa
     4741 ctcctagtgc taaaaaagaa ctgaaagtaa taccaattgc tgtatctcct tttattacac
     4801 tattgctttt tataaaagta ataatgatag aagctaatag accaaataca atcgcaccaa
     4861 taaaaaaatt aatacctaaa atataagaaa ttgctactcc tggcaaaaca gcatgagaaa
     4921 tagcatcacc cataagagac attcctctta aaataataaa acaacctact gttccagaaa
     4981 caatccctat aactacagat gtaattagag cattctgtaa aaagtgaaag tcatacagac
     5041 cattaataaa attttgaagc atattattcc ccctctccaa taaatatagt atctccatag
     5101 gcttttttta aattttcttc attaaataca gattctacac ttccgtgagc aattagattt
     5161 cgattcaaaa gaataatatt atcaaaatac ttctttacct tgcttaaatc atgatgcaca
     5221 attagcactg tttttccctg atgtttcaat ttttttaacg tatccataat tattcgttca
     5281 ctaactaagt ctatccctac aaatggttca tctaaaaata tgaaatccgc attttgagca
     5341 agacatcttg ctaaaagtac acgttgaaat tgtcctccag ataattctcc tatttgatga
     5401 ttagaatatt ttcccatatc gaccttttcc aaagcctttg aaactctttg ccattctgca
     5461 tttttaattc tttgaaaaac tttcattccg gcatatgttc ccatagatac acattctttt
     5521 acttttattg gaaaagtaaa atcaatatca gctttttgct ctacatatgc aatcttcacc
     5581 agttttttat tgatatcttc attattaatg gagacctctc cctgatgagg gataatattt
     5641 aacattgctt taagcaatgt ggattttcca gcaccatttg gaccaataat acctgttaaa
     5701 gcaccttctt gtatttttaa agaaatctcg ttcaatgcta aaaaatcgtt ataacaaaca
     5761 ttaagctttt tcacttctaa cataactttc tccttctaaa tgataatgat tatcacgatc
     5821 atatggtata caaaaattat attttagtca accctaaatt ttatagttta gatttttttc
     5881 tgttgctgaa gattagaatg acaaaactat ttgaaactac gcgtatagta agtagctttc
     5941 aaaatatata aaaaaggagc gttctcaaat gagaacatgc tcctaaaact actttattgg
     6001 cgtatggaaa aattatactt gaagtggata gcgggttgaa taagttgata agcatcaaaa
     6061 catttataaa aattattcaa gactatgtct gttccatata caaatatgaa aatcagtaaa
     6121 ctccatttaa cttttttcgt agtgtgtctt tttatacatg tttatcgtta ttaatagtga
     6181 ataggaaaaa aactattttt gatcattgac aattaaatac aatttttgaa taacgatccc
     6241 tgctattcga gctagaaact caagtacgcc atgacctgat tagcgacaaa tacttagaga
     6301 tttctttttg ttctgggaaa acaaaatgcc atgacaatag cagcaaataa tgatacttcc
     6361 gtaaggctcg ccgtaaactg gggagaggtg aaattcctat gtgcttaccc aaagcaattc
     6421 aaaaatttca taactactat tttaggagat gattttatag aatccagagt ctacctgaat
     6481 aaaaaacaaa cctgtgcatt tctaggaatc gataataata ctctagataa gtggattcgt
     6541 atatataatt tcccagtaat aagagttggt ggtgtagttc gctttgacgt agaagatatt
     6601 aaagacttta tgaatacatt taaaataact tgaaattttc ttctcgccgc atatactaaa
     6661 attagtgaaa tatactgcct tacttttttt aaggagtgag gattttgcct acaaagcttt
     6721 caaatgggaa atataaaact aatctgagat atccaaaaag gtttaaagaa ataacaggaa
     6781 ttgcatcaga aaagtatcaa aaaacatttc caaataggca attggcgatt aaagccgaaa
     6841 atgatatgaa gaagaaaata gaaaaagttt tgagagagga gaatgcaaac tcattagaat
     6901 taaaaggaaa aataacgttt aaaaaatttt acgaatctaa atggcttcct agatatgaat
     6961 taggtcaaac aattagatca aacaggcctc ctagtgatat aaccattagt aatacaaaag
     7021 atatatttcg gttgcatatt ttacctatgt ttggtgaata cgcaatgaat tatctaaata
     7081 tcaatactga gataatatca gatgaattaa ccaaaaaatc gaaagaatat gcaaatataa
     7141 aaatcataaa aggatatgtt cgttccatgt tcgatattgc agaaatacta aattatatcg
     7201 aatttaatcg aactactaaa attattcaaa gtatcactgc acctaaaaaa aatgctttag
     7261 aagaaaaaag aatacaagaa ggtaagcaag cactatcatc aaaagaactt actaattgga
     7321 tagaagcagt aaatgatgat tttaataatc atttacttac ttttcatgat tacacacttt
     7381 ttatgattac cctgtatctt ggtgatagaa aaagtgagac ttacgctttg caatggaaat
     7441 atattgattt tgaaaaacaa acggtccgtc ttaaacatac tttagataaa tatcaaagaa
     7501 aaaagtttac aaaaggtcga aaagataccg tcattcaagt accagaagtt gtaatgacat
     7561 tgctaagtga atggaaatcg gtacaagctg atcaattgtt gaaattaaaa attaagcaaa
     7621 cgttagatca gtatctcttt acttatacta aaccatctgg agaagtaaat tgtcctgttc
     7681 atgccgatta cctaaactat cgaatcaatt caattaaaag aaggcatcct gacttagttc
     7741 atttatctcc acacaaactc cgtcatactt atgcaactat agctagacaa ggtggagcag
     7801 atatgaatca aatttcaaat gctttaacac actcagatat ttctacaaca aagatatatg
     7861 tgaacacacc agatatagtt gataaggctg tttttgaagc ttttcagaga ggattgaata
     7921 agtgtgattg atatgtgttc ttaaatgtgt tcttaaaaac aaaagaagca ctttccaaat
     7981 aattgaaaag tgccagaaac gttgatatat aaaggatatt aacgttttga gaattgtgaa
     8041 gctttacgtg ctttcttaag acctggtttt ttacgttcga ccatacgtgc gtcacgagta
     8101 agtaagccag cacgtttaag agctaaacgg aagtcaggat caacttctag caatgcacga
     8161 gcgataccat gacggatagc tcctgattgt ccagcgtatc ctccgccgtt tacgttaaca
     8221 aatacgtcat atgcgccttt tgtttcagta acagcgaaag gttgattgat tacttcacgc
     8281 aagtcagcat gtggaatgta ttcttcaaca tcttttttat ttacagtaat tttgccagtt
     8341 cctggtacta gacgtacgcg agcaactgcg tttttacgac ggcctgtgcc gatatattga
     8401 acttgtgcca atgaaattcc ctcctattag attaagtttg tgatgtctaa aacttctggt
     8461 tgttgtgctg catgtggatg ttctgctcca ccgtatacgt tcaattttgt aaattgtttg
     8521 cggcctaaag tgtttttagg aagcatacct tttacagaag tttcgatcaa acgacgagaa
     8581 tttttagcac gcaattcgcc agcagtgatt gatttcaatc ctcctgggta gttgctgtga
     8641 cggtaataaa ttttgtcagt cgctttttta cctgttaatt tcactttgtc tgcattgatg
     8701 acgatgacga aatcgccagt atccaaatga ggtgtgaaag ttggtttatt tttaccacgt
     8761 agtacagatg caacaactgt tgaaagacgt cccaatggaa catcagttgc gtctactaca
     8821 taccatttac gttctacttc gcctggtttg gccatatatg ttgtacgcac gttattttcc
     8881 tccaatttaa gttctgatgt ttgacataca cttcgagttt ccggggctct ttgtggggca
     8941 aacaatacca tttaacatat tacccgctaa tctagtcaat gtcaacgttt ttctgcttga
     9001 ttgaaaaatt tatatgaaac tttacttctt ttctttcttt tatataaaag ggtcgtttcc
     9061 tgtcaaaatg aaaaacaaaa agaggctgtg acaaaagtct tgtcacaacc ccttattttg
     9121 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca taaaacataa
     9181 gaagctgttt tttaaaattg tttcttgtga ctcggagctg aacggcaggc ttacaacctc
     9241 ttggtaaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg
     9301 aggaactatt ttgacgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct
     9361 ctttttcggt caagttcaac aacagttttt acgcgtcgat ctctggcgct ttgcccaaat
     9421 gagcttggat catccagata cgtttttctg tggctgtttt gaattcgata aagatatctt
     9481 gtgttggatc gtcgccttct tctccagaaa cttcgattcc tttttggtaa agatctgcta
     9541 gataacgata gcctgcaaca agtgtttcca aacgttctgg aatagtacga tcccagcggc
     9601 caatttcatc agggattttt gtgttatctg caaattcacg caatgtagaa taaggtgaac
     9661 cgtctaatgt gatcaagcgt tcggatactt catctaactg agcgttcaaa tcatccatga
     9721 actcatccat cattgggtgc aatgtaagga aacctggtcc tctcatgtac caatgtgttt
     9781 ggtgaacaac aacagacatt tggcttagat ctgcaactaa ttgatttaat acttctttgg
     9841 tttgttggaa tttcatcttt cttgcctcct aacattttct tacacttaaa ataatagtag
     9901 actttcaatg aaaagtacaa caaaatcatt tacctgagaa cgattttcag ttcgcttttt
     9961 tatccgtaaa gccaatcatt tttcagaatc agctaattct tctcgcagtt gagcaaattg
    10021 ctgataagtc tgtgctaaat gcttttgtgt cgaaacaaat aatggataga ttttctgata
    10081 ttttttatga tcagtttctt gtactccaac ttgctctttc aattctatca attcctgtgc
    10141 ttcactgata ctttggatct ttccgatgct tctccagcct aaaatcacag ctcctaatgc
    10201 ggatgcttct gtgacagtag ggaaaacaag cgggtaaccc agtacatcag ccatcatctg
    10261 acgaaaaatc ggagattgag caaacccgcc tgtagcacgg atctctgtga gctgattttc
    10321 ctggcaaact ccttttaaaa tccgataaag gttgagacag atcccttcta gaatcgcctt
    10381 catcatttct ttttctgtat gttgccgctg taaaccgata aaactgccaa acgcatctgc
    10441 gtcccaaagc ggtgctcgct caccaagtaa atagggatga aaaatcagac cattggcacc
    10501 cgctggcaca aaagcgatag ccgaaagcag tgcatcatat ggattttctc ctttttcttt
    10561 agcagattga acgacttcct gtaaaaatgt atgccctgcc caatcaaaga tgccagcacc
    10621 attgctagtc gctcctccca ctacccaatg tttctgatcc agaacataac aaaacgtctc
    10681 catttctgga tggaactgag gctgagtagt aataaaacga agtgctccgc tcgttcctac
    10741 ggtcaaagcg gcgatcgtat caccaaaagc acctaaccct agattagaaa gcggcccgtc
    10801 tgcccctccc aaaacaaatg atatatcatt tggcaaacct agttctgctg ctgtttttga
    10861 tggtagacct gttacttgat aggtggaagg aaagacttgc ggcaattgct ctattcgaat
    10921 gttcaagtag tcaagcactt cttctgccca ttggaattca tggatatcaa aatatccagt
    10981 tcctgaagct gttccgtagt cgctgatcag ttcgccaaac aatctataaa agatatagtc
    11041 tttgataccg acaaaataag cagttttttt gaataattca ggttggctgt tttgcagcca
    11101 cttgattttg ttcaatggtg tcattggatg aatcggcgtc ccagtctgcc gataaaattc
    11161 tttgccaagc acggtatatt tcagtttttc tgcttcgtcc gctgctcggt tatctgccca
    11221 agtgatcatt cgagataacg gtgttttctc ttcatccaac aatatcaggc catgcatcgc
    11281 agaggagaag gagacaaatt gaatgattgt gtctgaaggc aactgtttaa ttacttcttt
    11341 tataacggtg cagacacctt gaaagatcaa ttcctgatct tgttctgcca tcccttgtgt
    11401 ttcttggatc aaagggtagc gaaaataagc ggatgctgct tcttgggctt catctgtgaa
    11461 agcaactgct ttggtttgtg tggttccgat atctaatccg attgaaacgt tcattttttc
    11521 acctcaaatt ttatgtatgt acaaaaattt agtttaagct tgcgtatctt ggttttgaaa
    11581 agggggagat ggcgtgttac tttattttat cattggttgc tgtatcggat catttttatg
    11641 tttaaccgcc cagcggattc cgttaggtca ctctattatt tatcctagat ctcattgtgt
    11701 caaatgctgt cgttcgcttt cttggtatga attgattccg attctctcga tcatcgtcca
    11761 acgatttcgc tgccgctatt gcaggtgtcg gttgcccttc tactatttgt tggcagaagc
    11821 cttatgtggt ggtctttttg cctggttctt tactttttct tccgcaagaa atttttcgac
    11881 gttcatatgg atgctttcgg ctttgctatt ttcgttgatg gatttatttt acttcatggt
    11941 ccattctcac acgctattct gttcttgggc aattttatgg attttttggt tgcaggccgg
    12001 cgtcttccaa tggcaaagtg tgctgttaac gtttatcgta ggcggtgtgt gccttcgcta
    12061 tggtcaatcc tatctcggag ctggcgatac tctgttgatg ctttcttgga gtggtggctt
    12121 gtctctagaa gagttgcttc agatcttgtt tcttgctagt ctgtttggaa tatccgtttt
    12181 ttctgtttac tttatctgtc ataaaaaaaa gttggaaaag ctgcctttca ttcctttttt
    12241 gagcagtgcg ttgctgattg tccttcatct taggtattga aaaaaggttg tgacaaacga
    12301 cttgtcacaa cctctgatat atagtgttct cttaccaaat ccttgtgact tggagctagg
    12361 cgacaggttc acaacctctc cactaaatgg tgttcaatca gctgaccctc agtattagct
    12421 caaaatgctg gttttacaac ctctgatata cggtgttcca taagtagctt tttcggcttc
    12481 ttatttcttg acgccccaat gtcgacgaag gaaacctgca cgtccagaac cttctcgata
    12541 aagattgtaa tggagcttgt ttttcttgta ataatcctga tggtaatctt ctgcaggata
    12601 aaattcgctt cttggttcga tttttgtcac gattggctta tcgaatcgcc cgctgtcttg
    12661 caatgcttgt tttgaacgct ctgcaatatt tcgttcttct tcatcattat agtagatcac
    12721 tggacgataa gaatcaccgc gatcagcgaa ctgtcctaat gcgtcagtcg gatcggtttg
    12781 ctgccaatag atttccacca actgatcata agaaataact tctggatcat attcgatctc
    12841 tactgcttct gtatgccctg ttgtgcctgt tgttacttgt tcataagttg gatttggtac
    12901 atgcccgcca gtataaccgg atgtcacaga aatgatccct ggctgctctt caaatggttt
    12961 gaccatacac caaaagcatc cgcctgcgaa aactgctttt tttgtcatat aaaatccccc
    13021 ttttttctca tcataccttg atttccaaaa ggaggataac gttttgcttg tgacagaaaa
    13081 aacggaaact attatatacg tgatacggct tctgataaat gccaaaacga acgtacttga
    13141 tcaaaaacgg ttaaatcagg aatcacatat tcagcagaag gaagatttat gttttcacct
    13201 attcccaata catgcatgtt accagccaaa gctgcttgac aaccagcttc tgaatcttca
    13261 atgaccaagc atgcatttgg cggtacattc aattgctgtg ctcctttgag aaaaacttct
    13321 ggatcaggtt ttgcttttga tacttgcgtg ccgtcaataa ggacatcaaa ataacttgtc
    13381 aaattcgttt tttctaaaat gaggcgtgca tttttgcttg ctgatcccaa tccgatcttg
    13441 atgtttgttt ttttcaagta ctcaagaaca gctattgcac caggcaaaac ggatgtttca
    13501 tccatttttt gaatcgcttg aagatataga ttgttttttt gctcagcaaa ggctgatttc
    13561 tctttttctg agaatttctg ttccattttt ccaaatgaca gcaatcgctc tagtgactcg
    13621 gttctggata ttcctttcag ttgctcgttt tctttctcag tgaatggaat ggacagctgg
    13681 ttagctaaaa ccagccacgc ttcgtaatga taacgagctg tgtctacaag aacgccatct
    13741 aaatcgaata gtgctgcttt gattttcatc gattacctcc ttgaaaatga acgacttgaa
    13801 gtaaagatgc gatgttttta gctgtgcgat gaagattatc agtggcttgc tgtaaagctt
    13861 cttgtaaagg cacagctgca ggaaggatcg gaaaaacggc cgaaatgcca acatctgctg
    13921 ctttttcgct tcctttacca acacttccgc aaatagctat cacaggaacg ccctctggta
    13981 ctcttctagc aatcccaact ggcgcttttc cttttagact ttgtccatct agacgtcctt
    14041 cgcctacgat tacgaggtct gcttgctgta cccgtttatc gaactccagt aaatccaata
    14101 cgtagtcgat gccagagact attttccctg aagcaaatgc taacagtcct gcacccattc
    14161 caccaccagc actactgccc gatgcctcga ttacttgagg ggcaaatctc atataaaaat
    14221 catgcatggc ttggtcagcc actgctaatt cattttcttt caagcctttt tgtggtccga
    14281 aaacaaaaga agcgccttct tttccgcata aaagattagt aacatcagta atgacagtga
    14341 ttttggcttt aatcagctca ataggcacgt tcgttttatc aactgtagca attttaccta
    14401 gattttctcc cagtgcttct actttttgat tatcttgatc gtaaaaagca taacctagac
    14461 cttctgccat gccgatgccg ccatcgttgg tactacttcc gccaacgccg atgatgatgt
    14521 gtcgaacacc ttgttgcaac aattgtcgta tcagttctcc tactcctcgc gtggataacc
    14581 taagtggctg ttgttggttt agtgggacat ctttcaatcc gacgatttct gccatttcaa
    14641 aaatcgcagt ttgaccgtct gaagcgtact ggatttcttt gtttttgcca aatgcattag
    14701 taacgactgc tgtttgccgc ttcaacctta aactgtctgc taatgatgaa accgttcctt
    14761 ctcctccatc gcctataggt agcagatcat attcagcctg aacaaaaact tcttgaaaac
    14821 ctgattgaat ggcttgtgct gcctctaagg ctgtcagact ttctttgaaa gaatctggcg
    14881 caatcagaat acgcattatt ttcccctccg ttccaagatc agttcttttt ccagctggta
    14941 ttggtctcca ttgacaaaaa taggtaatgt ttctttcgtc tcttttttta ttactatttg
    15001 tttttttgtc aaaacaaata gcaacctgtg atttttccaa ataaaaggaa aagaaatttt
    15061 ttcccatgct gaaggaagtc ttggagaaat agaaagagtt ccattcgtta ctgtaatacc
    15121 tgaaaaacca aatataactg ctagccatag tgctcctaat gaagcagcat gaattccgtc
    15181 atctgatgaa tgcggatctg gtcctaaatc aatcaggcac gcttcttgga ataaatgata
    15241 cgcccattcc atttcttgga tacggcaagc ctctatggcg tgaatcgctt tactcaacga
    15301 tgagtcgtgg attgttttgt tttcatagta atgcaaattc ttagaaacga ttggttgaga
    15361 aaaatactca ggtaataagt ataacagcat gacaagatct gcttgcttgc tgacttggag
    15421 ttcatttact tcgctacggg cataatcaag taaaatagac tggctgccag gacgttcttt
    15481 gtaagtggtc aaatcaataa ctggcttact gagatacgtg tcatcttgcg gaatcagctg
    15541 ttctttgtta ggcactggca aatataactt atctaaaaaa ttttgacatt ctttcaaaaa
    15601 aagcggatcg ccagcttgat atttaacagc taaggccaca ttataatgcg ccagatagtt
    15661 cgtatatgca ttattgtcga tatattctgt gtattcatct ggaccaatga ctctgtgtat
    15721 ctctaaatga tcatcgactt ttacagctct gctcagccaa aaagctgctg tttcatgaat
    15781 gagcgttttt ccctttgttt ctaaaaacga ttgatcctct gttgcttgga catactcttg
    15841 aacggcataa gcaaggtctg cactgatatg atgttctgcg gcagctgaag caacttcttg
    15901 tcttgttccg gttttgatat tcaatgcagc aaatttgggt gtctcttcct gaccagtgtg
    15961 tgcgctttcc catgggaaaa gtgcaccttg atagtgataa tctcttgctt tttgccgtgc
    16021 gccttctaat cgatcataac ggtacagcag caaattcttt gctacttcag gaaactgata
    16081 taaaaagaaa ggcaggataa aaatttccgt atcccagaaa acatgccctt tataaccttc
    16141 gccagttagt cccttcgccc ctacactaac acttggatca ttgcggggag tcataatctg
    16201 taaatggtaa gcagcgaagt ccatcgctaa ctgatcgaaa gaagaatcgc cttggatcgt
    16261 tatccgatgc tgatgccaaa aatctgtcca ataagacatc gactgctcta aaatttctgt
    16321 ataactaacg cttttctggg cttgggcaat acttttctta aacgggtctg tttgctgaag
    16381 agaggtagag agcacgatga tcttctccag cgtaaaggac gtattttttc tgatcttttc
    16441 tgaaaaggaa gcggtgatcc ggcgattttt tgcttggaat acacctgctt tattgaattt
    16501 agctgcaatc ccaatatcaa ttttactttc tgttgtctgg taggatgcac tgatcaaatc
    16561 gtcaccaaat actcgcagtt ctttttcaac caactgctgt gtaccaaaat tggtttgctg
    16621 tccatcgata cccgttttca catctacttg gcagtcttcg gtcaacggct tgatgaccac
    16681 tttcagggct gcctgatgga gattattttg atcagcaaca cgacaagtaa tgacttccac
    16741 tttttttcct tgagcagttt caatgagcgc atagcgttta agctctccca tttctaaatc
    16801 tagtgcccgc tcgtatgcaa gaactttcat cgtctcaaga gaaaaatgtt caccgtcgat
    16861 ttttatttcc catctgatga catctgggag attcactaac tcggctgatt ctgctcctaa
    16921 aggtcggtta tatacaccag ctgcaaacat tccccttact tgattccgat agtcttcctc
    16981 ctggcttcct ctgataccaa aaaatccatt tccaatggtc atctgactcg catacttatt
    17041 gatatactct aaatcaaact gtttttcttc tactttcata aggtaataac ttctcctgtt
    17101 tctgccgaac gatataaatt ttccaccaga ttctggatga catatccttg ccagccatct
    17161 gcaatcatct gagtctggtc accgagcgcc cgattcacaa aatgagccat acttagttca
    17221 tgtgggtcat taactggcgt ggtcttttgt aaggaaacca gctttccatc tacatcttcg
    17281 aatagttcgc ctggatacag attagcacct gcctgatcgc cacaaaaagc cacattcagt
    17341 ttgtcttctc tgatattcaa agcaaacgaa gtattcagtt ggatgatctt gccgttttct
    17401 aattccagtg tgccaaaaat tgcatcttct actgtgaatt tgcttggatc ccatttcccg
    17461 aatttccctg aatttttttt cgtaccaatt ttttggaagc tgtacgcccg aacgcttttt
    17521 actttaggaa atccagtaat atacatcgct gtatcaagca tgtgaatgcc ataatcgatc
    17581 aaaggcccgc ctccttgaag ttctttgtcg ataaacgttc cccagcctgg aacaccagac
    17641 cgacgaagcg cattcgcttc tacgtaataa atatccccga gaacatcaag atgattcttg
    17701 atcattgttg cttcgtcaga aaaacgatgc tggaatccat aagccaaaat ctgcccgttt
    17761 ttatcggctg tctctgccat ctttcttgct tgatcagctg tcatagctgg tggtttctcg
    17821 cacatcactg aagcattagc ttcgagggca gccaatacat gttcgaagtg aaagcgattg
    17881 ggtgtacaga cactcacgat atcgggagaa atctcattca gcatttgtgt aactgatgta
    17941 tacgcatgag aaaatcctgt acgtcggcaa aagtcttctg ctcgctggct gactggatca
    18001 accacagcgg ccaattctaa gacatctgat cttttttgat aataagcagc atgtactttt
    18061 tctgctactt gtccagcgcc tatgattgct actttcttca tttatttctc cctcctttgc
    18121 ttatttactt attgttattc tttctctatt ctttctctaa atcatttaaa tgacgcgctg
    18181 tttccagaca gtttttcaag tattgcaatg attcctgata aattttcact tcattttctc
    18241 ctcgcaaacg acattcatat accatataac cttcatactc attttgaagt agcgtttgaa
    18301 aatggcgagt aaaatcaatt gcgccagatc ctggttggta gcgatgatta tctgctaaat
    18361 ggatatgacc cacatactct ttttgcgtag tcaatgcttt tgaaatatca tcttcttcaa
    18421 tattcatatg ataaaaatca gcgatgatct gcacatgttt caattgatta gagtcaatgt
    18481 aatgacgcgc atccgctaac aaattgatca tatggtcttg gtatcggttc aaaggctcca
    18541 aataaataac cgtacctgtt tcttcggcta ctttatctaa ataacgaagt gattcgctga
    18601 ctgctttata gtctccttct ttgcttcggg gtgaaaccat cggcggtaat cgataagtga
    18661 acattcccca agctgctggg ataacgattc ctttgcctcc aacctcgctt agtgcacgca
    18721 aaatctcagc aatttgacgt acaccattaa gacgccgttc ttcgataaag tcaccgatcc
    18781 acccatcgta gccgttacaa gctgtcacta ctgggatccc tgtttctttg attgcctgtt
    18841 tgactgtgtc gatattttct attaacaact taccgtcgat ttcgtattct tcaaatccac
    18901 agtctttgat aaatctaaat ttttctaaaa tgtctcttgg gaaaaatgct tgatcttgcg
    18961 taccgaattt cattgttctc ctcctcggac ttgaacgccc attttgatac tttcttctgg
    19021 gtgctggtct acataacgca tgtaagcttc tgcgctttct gcaaatggca caactggatc
    19081 aatgatttct tcacaatcca agtaaccgtt catcaataat tcccaacatg tgtcctcgat
    19141 tcgtttacgg ttccatcttg ggtaatctgg gtttggttca ctagatgctc gagcaaagac
    19201 gatttttgca ttattgaaat gtgcttcgcg accaagatta aacccagctg gaaaaggttt
    19261 agcaaaggca acataagaaa tgatcccgcc atagccgatc cctcttaaag aagcttgtaa
    19321 tgcggcagca ctgccactcg tttcaataac tgaatctact ccacgtttat ctgtcaattc
    19381 ctttagacga aaaccgacat ctgctttcat aggatctagc gtgtaatcgg caccgtattt
    19441 ttctgctaat tctctacgct gcgctatggg atcgatccca acgatggtag tagcacctgc
    19501 ttttttagct aattgaatcg caatttgccc gatagcgcct aaaccgaaga ttgctacagc
    19561 atcacctgct cgaacatgtg cttcccggat accacctaaa gcgaattgag caggatcgta
    19621 acatactgca tttttccatt gatccaaccg atcaagttta cgtagtttat aattatcaac
    19681 accgtttgta atcagcgttt cacgaatggg tccataagtg cagactaact ctcctttttg
    19741 atactctgtc accaaactgc ccgtttcttc gatcgtaccg acaatcatat ttcctaattg
    19801 aaattcgcca aataccacac cgcgttggct tccttcttct cttggcaaga ataggcgcca
    19861 ttcttctgaa aattcttcat cgataaatgg acttaatcct ctaaagtcga caatttctgt
    19921 tcctggtttt ggagtagcga aaattactcg gatacgtact tcgttctttt cgatctcacg
    19981 gtcttcgtaa tctttgaatc cggctattct tggttctaat gcaactaatt ttttcatctt
    20041 ttctttcctc tttcttttct ttttatcctt ttacgccgcc ttcgactaaa tcacctttaa
    20101 taaatcgttc agataacgca tacataatga tgactggtaa agcggtcacc aatgaagcgg
    20161 ccatcattcg tccccaaatg tagtctggtg tactgaataa tgtgttcaaa ccgattggta
    20221 aagtaaattt ttcggaggtc gacaggaaaa tcgaagcaaa taaataatca ttccacgaaa
    20281 ccataaagca ataaacgaag acagaaatga ttccagaaat agccaatggt ataatgatcc
    20341 gaataatgat ctggatccgg ctaagaccat cgatcattgc tgcttcttca atatcagtcg
    20401 gaatcgtgtc aaaataactt tttagcatga atatcgcagt aggaagtgtt tgaacgacca
    20461 tcgtgataat cagtgctgta ttggtatcat acaaacctag accggaaatg attttaaata
    20521 atggaacaac gatcaaaata ccggaaaaca tataaacggt gtaaaagcta gcattgattt
    20581 tcgagcgagc tttgaagcgt agttttgaca aagcgtatgc cccgctgatc ccaatcacta
    20641 ctgcagttac ggaggctatc aaggagatca ctaaactatt tttgaaatac atgatgaatg
    20701 gaaaaatctc agcattgaaa atatcctgat aatgttcaaa agtccattct ttcggaaaaa
    20761 tagtttgtgt cgttgcaatt gcttcttgtg aatccttgaa tgatgtcatc agcatgatca
    20821 aaaatggaaa caaattgaca gctaatagca acaaaatcgt cgcgtaaaat aagattttcc
    20881 tgctcttttt atttttcatt tcaagtccac cttctttcgt gagagcaaga cgaccgctgc
    20941 aataatgatg aacaatagaa tcgatatagc tgctgctttt ccaagatcat tgaacgcaaa
    21001 ggctgtctga tacaaataaa cgcctaagat attgacttta ttcgtcagta gatagacatc
    21061 tgtaaacata tagaacatcc agatagatcg taaaacaatc acagttgcta gtactggttt
    21121 gattgccggc agtgtcacga tcttgaactt ctgccaagca tttgcaccgt ccatttcagc
    21181 tgcttcataa agcgttttgt cgactgtttg caaaatagcc aaaaatgaaa taaacgcata
    21241 cggatagtat ctccagatag caaacaaaac gaccataaag aagctagcaa ctggctggtc
    21301 gaaccacagc ggtgcttcgt tgaaaagctg caacctatct actaacagat cattgacgat
    21361 tccataacta ttattgaaca tatatttcca agcaaaaatc aaagaaatag atggcgtaac
    21421 ataacttaat aaaatcagtg aacgcaccgt tttcctaaat ctgaacttgc ggttaagcaa
    21481 aatagctacg gctaatccta aagctgtact gcctgctaca actaagaatg tgtaagcaac
    21541 tgttaaacct aaagaacgat aaaattcact atcacttaaa atttcaagat aattgcttaa
    21601 tccgataaaa acggcgtctg agttaggatt cagcggcata tcgaaaaaac tgatctgaat
    21661 attggaaagc attggaatca gcactaaaac agctaataaa agcatgcttg gtgctaaaag
    21721 tcccatggct aattttaagt cagaatgttt ccttggacga ttcattgaaa cctccccctg
    21781 ataatctgcc aatagctatc tacttttttc gaacaccatt ggcagaactt cttgttattt
    21841 cgtatttttt tgtgcgtcag ctaaagcttg atcgacatct tcgtttccga cagttacttg
    21901 gttcactgct tttccgatca cacctgagct tgtgatatct cccattttcg tgaaattctt
    21961 ttccccgact agtccaaaga cttgtacttc atcaaaagca ctagcaatct cagatggcag
    22021 ctcgccaaaa gacttgatga cttcattttc tttgtaacca tccagttcga ctacttgttt
    22081 attcactggt tgagcaccac caggagacat caagacccac ttttccatgt ttttcggttg
    22141 agataagaaa gctgtgaatg cttcagcagc ctctttttgt ttctcgtcta gaccagaaga
    22201 aatcgtcaat ccagatactg tgccatagac agcttgatct ttttgtgttg ggatagcaaa
    22261 accgatattt tctgagttcc ccgcttcata aacagaaggc aaaatgtaag ttgaatagat
    22321 tgccattggt gctgttccat tcatgaaagc atctttgatt tctgtcacat cattagagcc
    22381 tggcatcgtg tattgggata agttttgata aaacgacaat gcttctctca tcttttccgt
    22441 atcgatcgtt acctcgcctt catcatccaa aacatttgct ccatttgaca aagcaaattg
    22501 agagaacgct tgctcactca ttgttccttc agcagtaggc atagcaattc catattgttt
    22561 attctcttta tctgtgaaat gttgagcaat ttttaaaata tcatcccaat tttctggttc
    22621 tgaaaaacca gcttctgata atttttcttt gtcataccaa ataccttgaa cccagccgct
    22681 aattggtgca gcaatatagc tttttccatc ttctgaacga acaaggtttt tggctccgtc
    22741 ataataatta tcttctccag cttcctcgat aacgttttgg actgccgtct gatcaatcag
    22801 ttcatcttta tccatcactt tagcaaaatc ctgactgact tccattactt ctggtaattt
    22861 accggaacga gctaacgtaa cgatttttgt attgaacgct gattcttcta ccggcacttg
    22921 cttgattttg atgtctggat tttctttttc aaaatcagca accagttcat tgatcacact
    22981 taatcgttcc tgttcgacag aagagtgcat gaattgaatc gttgtctgtt gtgattcgtt
    23041 agagctttga ctttcaccac aagcagtaag aagaaatcca gtagctagca gacaggtagt
    23101 aacaataatt tttttcattt ttttccacct cttattttat tattttcagc cacatatatt
    23161 catacggctg gaatatcaac tttcgttctt gactgcaatg gataatttgt ccagaaaaca
    23221 ggtctaggta atctcctttt ggtaaaagat aacctgctga ttgattggaa aaattatgga
    23281 taactaagac tttctcttcc ttcgcttcgc gaataaaact gataaaagaa tctgctgagt
    23341 ccagtaagta aatcaaacta ttcggatgga aggctttttc tttttttcga atagatagca
    23401 tctgggtcaa ttcaccatat actgctgttc ttaatggatc tgtctgcaac tctttctcaa
    23461 tatctgctaa caaaaatttt tgccgattga tttttcgatt ctctcctgtt ttttctacgc
    23521 ctttgtaatc atttcgactt cccagcacac tttgaatata aattgccggc acgcctggta
    23581 acgttaccaa aaatgaatga gcagctaaaa agcgtttgct tctccattcc gtcgtatctg
    23641 ttggagaact taacgcatct agatacgtag cgtttatctc atatggactg gtcgttccat
    23701 ctgggttttt cttgtagttt actcgggtac cctctttctt cagctgttcc actaattcaa
    23761 ggatcgtttt ttccggcaga atacctcgta ccggattcaa tccgataccg tcatgggagg
    23821 ctaaaaaatt aaaaaaagtt gtttttttcg atgcgaaatc gatggttttt aaccattctt
    23881 tcaacttact tgtattaccc gaacgaatcg cttgaagggt caaaggtggt agcgaaaact
    23941 gatagaccat ctgtgcttca ttctcgccat tcccaaaata actgatatta tctttgtgtg
    24001 gcacatttgt ctcagtgatc aataccgttc ctggagctgc ttcatcagcg attgcacgga
    24061 ataattggat gattttatgc gtttctggca ggtgtataca agaagttcct agttctttcc
    24121 ataaaaatcc cacagcgtcc aagcgaataa atgaagcgcc tttttctaag taaaacaaaa
    24181 gaatatcgat cattttcaat aaaacttctg gatttttaaa attcaagtct acttgatctt
    24241 cgctaaaagt cgtccatacg tgtttttctt tcccgttttt gtcaatgaac gttgtaagta
    24301 acgggctggt ccttggtcta gtcacgctgc ttgtatctgt atccagtggc aaatcaataa
    24361 aaaaatcttt gtacgtatca ttcaagttta aatattcctg aaaccaagta ctttcggcag
    24421 acatatgatt gcagacaaag tcgaacatta accgtgtttc gcttctcatt tcttctatat
    24481 cttcccatgt gcccaaacgg tcgttgattg cctgataatt tacaacggag aaaccatcat
    24541 cagatgtata tgggaaaaat ggcaagaaat gtacaactct aaatgtatct gccaaatact
    24601 tttgataaaa tttcttaaat gtacgcaaag ttggttgctg ctcttcaaaa aattgatccc
    24661 cataagtaat caagaaaata tcttcttcgt cccaatgcag tttgcctgcc tggcctttct
    24721 tctgctgata aacactgact ttttgttcaa tcatagaggc ggttttctca gacaaatctg
    24781 agtcgcgata aatcgcttgt aaaagttttg tatacatcgg attccccttt cttttttggg
    24841 agcgttccca acgatttgat catattatgg aaaacgctta ctgtcaatag cattttttta
    24901 aataattttg atatacacaa aaatacaaat aagaaagctt atgtatcaat aattaatagc
    24961 ttcttaaaaa aatatggtct ctcatgatca tgcaagctat tcctaaattt tcaaaatcat
    25021 agacaaaaaa gaatgtctat tgtactatgg aattattcta aaacgctccc aaaaaggagg
    25081 tgcatataaa attgaaacct actatttatg acattgcgaa aaaagctaat gtctcaaaat
    25141 caactgtctc cagagtatta aataaccagc caaatatctc tgataaagca aaagcaagtg
    25201 tacttcaagc aatcaaagaa ttgaattatg aaccgagcaa aattgcaaga ggactgtcag
    25261 gaaatggttt tgacgcgatt ctagcattat ctcatcgtac ttctcatacg acctatggca
    25321 atcctttttt ttcagatgtt attcaatcca tttctgccgt ttctgaacaa aataacttcg
    25381 acttgattct acaaacggca aaaacaccag aagaagagct agaaaaatgc gcgaaaaaga
    25441 tccaagaaaa aatgatccga ggaattatta ttttaagctc tacgatggat gaaacacttc
    25501 tttttgaatt ggatcaatac aatattccta ttgtggtaat cggaaaagtc ggaaacgact
    25561 acacgaacat ctactcagtg gacacggata atttccagga tagttacgat ttggtggaaa
    25621 cactgatcaa gaatggacac cgtcatatcg gctgtctcca tgctccgaca gaagtttatg
    25681 tatccaatga tcgtctcaat ggttaccgtc aatgcttatt tgatcaccac ctagatatcc
    25741 gtaatgaatg gattatagac ggcggctttc gcttagaaga tagcatggca gcaatgaatg
    25801 atttaatgaa gctacgagaa agaccaactg cgattttttc taccgatgca ttaaaatcat
    25861 tgagtattta caaagtggca gaacaatctg gaaagcagat acctgatgat ctttcgatcg
    25921 caggattcag tgatccctta ttgtcctccc tattttcgcc acagttgact cggatagaca
    25981 ttccgacaaa tcagttagga atcaaagcca cagaactttt attccaacta atccaccacc
    26041 aataccctga agaaaaaaga atcattcttt caaccgagat tactctcaca gattcgatcc
    26101 aacaacaaga aatgtagaac agaattataa aagaacagaa acactgagga taagtcagtt
    26161 actctgttct tttttcaatc actcatccct cgttaccccc tcccggtatt ttagcgaatt
    26221 tttcttattt tccatctgtt ttagatagct gtggataact ataatgtttg tgttaaacta
    26281 ttttttccac agggaagaaa aaactatttt taaccacgtt gtgtataagt ttttatagtt
    26341 cgttttttta aacacattta cccttatttc aatccatgtt atttggggat acttatctct
    26401 aaaacataaa tagaataaca gacatgtcta ctggttttgt tttattcgag gaattattca
    26461 ataatagcta gcaaaatatt aaaaataacc gctctatctt cccatcaatt tattttgcat
    26521 tcaaaaaatg atctatcttt acttttgttg attgacttct cttggaagat gatcgttccg
    26581 ataccttaat tggatacgaa ccgatgttgt taagatcctt tcccactttt cttctagtta
    26641 gacaaattat tttagac
//
LOCUS       DAFLWZ010000034        26041 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000034 DAFLWZ010000000
VERSION     DAFLWZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.034"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(207..659)
                     /locus_tag="L1V38_001513"
     CDS             complement(207..659)
                     /locus_tag="L1V38_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1316066.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(672..1082)
                     /locus_tag="L1V38_001514"
     CDS             complement(672..1082)
                     /locus_tag="L1V38_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316067.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1357..1569
                     /locus_tag="L1V38_001515"
     CDS             1357..1569
                     /locus_tag="L1V38_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316068.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1572..1784
                     /locus_tag="L1V38_001516"
     CDS             1572..1784
                     /locus_tag="L1V38_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316069.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1924..2079
                     /locus_tag="L1V38_001517"
     CDS             1924..2079
                     /locus_tag="L1V38_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316070.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2076..2300)
                     /locus_tag="L1V38_001518"
     CDS             complement(2076..2300)
                     /locus_tag="L1V38_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1316071.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2378..2566
                     /locus_tag="L1V38_001519"
     CDS             2378..2566
                     /locus_tag="L1V38_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316072.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2892..3227
                     /locus_tag="L1V38_001520"
     CDS             2892..3227
                     /locus_tag="L1V38_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316073.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3460..4401
                     /locus_tag="L1V38_001521"
     CDS             3460..4401
                     /locus_tag="L1V38_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBN1316074.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4403..5293
                     /locus_tag="L1V38_001522"
     CDS             4403..5293
                     /locus_tag="L1V38_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1316075.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5336..6136
                     /locus_tag="L1V38_001523"
     CDS             5336..6136
                     /locus_tag="L1V38_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBN1316076.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6151..7002
                     /locus_tag="L1V38_001524"
     CDS             6151..7002
                     /locus_tag="L1V38_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1316077.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7203..7664
                     /locus_tag="L1V38_001525"
     CDS             7203..7664
                     /locus_tag="L1V38_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1316078.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7690..8142
                     /locus_tag="L1V38_001526"
     CDS             7690..8142
                     /locus_tag="L1V38_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316079.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8248..8442
                     /locus_tag="L1V38_001527"
     CDS             8248..8442
                     /locus_tag="L1V38_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316080.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8473..8859
                     /locus_tag="L1V38_001528"
     CDS             8473..8859
                     /locus_tag="L1V38_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316081.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8856..9059
                     /locus_tag="L1V38_001529"
     CDS             8856..9059
                     /locus_tag="L1V38_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1316082.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            9056..9352
                     /locus_tag="L1V38_001530"
     CDS             9056..9352
                     /locus_tag="L1V38_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316083.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9428..9844
                     /locus_tag="L1V38_001531"
     CDS             9428..9844
                     /locus_tag="L1V38_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1316084.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            10105..10242
                     /locus_tag="L1V38_001532"
     CDS             10105..10242
                     /locus_tag="L1V38_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316085.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            10652..10882
                     /locus_tag="L1V38_001533"
     CDS             10652..10882
                     /locus_tag="L1V38_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316086.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            11041..11874
                     /locus_tag="L1V38_001534"
     CDS             11041..11874
                     /locus_tag="L1V38_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBN1316087.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11867..13282
                     /locus_tag="L1V38_001535"
     CDS             11867..13282
                     /locus_tag="L1V38_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBN1316088.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13294..14823
                     /locus_tag="L1V38_001536"
     CDS             13294..14823
                     /locus_tag="L1V38_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1316089.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14741..15793
                     /locus_tag="L1V38_001537"
     CDS             14741..15793
                     /locus_tag="L1V38_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1316090.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15795..16112
                     /locus_tag="L1V38_001538"
     CDS             15795..16112
                     /locus_tag="L1V38_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316091.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16239..16862
                     /locus_tag="L1V38_001539"
     CDS             16239..16862
                     /locus_tag="L1V38_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1316092.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16877..17767
                     /locus_tag="L1V38_001540"
     CDS             16877..17767
                     /locus_tag="L1V38_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBN1316093.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17790..18005
                     /locus_tag="L1V38_001541"
     CDS             17790..18005
                     /locus_tag="L1V38_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316094.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18017..18358
                     /locus_tag="L1V38_001542"
     CDS             18017..18358
                     /locus_tag="L1V38_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316095.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18358..18729
                     /locus_tag="L1V38_001543"
     CDS             18358..18729
                     /locus_tag="L1V38_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316096.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18722..19117
                     /locus_tag="L1V38_001544"
     CDS             18722..19117
                     /locus_tag="L1V38_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1316097.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19119..19496
                     /locus_tag="L1V38_001545"
     CDS             19119..19496
                     /locus_tag="L1V38_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316098.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19497..20105
                     /locus_tag="L1V38_001546"
     CDS             19497..20105
                     /locus_tag="L1V38_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316099.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20105..20446
                     /locus_tag="L1V38_001547"
     CDS             20105..20446
                     /locus_tag="L1V38_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316100.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20688..23477
                     /locus_tag="L1V38_001548"
     CDS             20688..23477
                     /locus_tag="L1V38_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1316101.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23467..24207
                     /locus_tag="L1V38_001549"
     CDS             23467..24207
                     /locus_tag="L1V38_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316102.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24204..>26041
                     /locus_tag="L1V38_001550"
     CDS             24204..>26041
                     /locus_tag="L1V38_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316103.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         9462 a         3705 c         5319 g         7555 t
ORIGIN      
        1 tttagttttt catcattttt ttgttctaat tcataagctt ctttttttat tgtgttagct
       61 ttcgacagtt tagtgattcc tataattaat aaaataagtc caatcaataa taacattcaa
      121 aactcctcat ttctttgata taattattgt agagtttact cagaaatgag gaaagagtcc
      181 atgtgaaagc atgggctttt ttatttttaa tgttgtaata ctaaatgttc aagattatga
      241 ggaagcccta aatattcaat aatttggaac tgactcatat cagataaatc ttgttcatct
      301 attgttctag ttaacatttc aattgcaaac atattagctt cagcttctat accataaatc
      361 atacaactaa ggttgtttgc tctaaaagct gctgtgcaaa tacctttatg gagtctaacg
      421 tgggctattt catgccataa tacaaatctt ttcatagaag gtgataggtt ttgattaatt
      481 aatatcacat aacatctttt attgtgtatc gtttgtccta atgttttatt ccctaaatca
      541 gtttcaatta aatctatatc agaatatttg attattttat atggattaat cgcatcagat
      601 ccaaactcta caaataattt ttctatttct tctaatatcc agtatttgtt taaatgcata
      661 ccaaagccca cctattgacg atatttttta ggagtgaatt ttttctttgc tttaactttg
      721 gttaaggcaa gtgcaagttg aatggcatcg tataattttt ccttatcttc atcgtctaaa
      781 ggttcaccat aataatttgt ttcagcatct gaattcaagc cttcaagtaa tttttcagct
      841 tgtaaagcaa tatcttgttt atctttttct gttaaatcat aataatggcg tttatcagta
      901 cgtcctaaaa gataatcagt tgatacatta aagtaatctg caactttttg tattttatct
      961 ccagatggag tacttttatt ccatctagac atgcttccat ttccgaaatt taactttctt
     1021 tcaagttctg ccaacgtcat tgaacgttct tttaataaga tttttatacg gtctaatagc
     1081 ataggatatg cattcctttc aaaataccga caaaaaaagt atttttctgc aaattatcta
     1141 tttacaaata gagaatttgc agttatacta gttttgtaag caagatattt acggcataca
     1201 aagactaaaa gcaataaact aatagtctcc ccagacatca gtaagctcgc tttttgtgcg
     1261 ctgtattttg tatgcttaca taatagcata tttgcagttt ttgtcaaact tattagacaa
     1321 aaatattaga aaatattcga taagggggta tgaagcatga ctttaaaaca gcaagtatta
     1381 attgctttag taaagaaagg ttggagtcaa agagagttag ctcgacgaat gggtatatca
     1441 attacttatt tacgagatat cttcatcgaa aaaagaaaac ctaaggaacg tttaaaacaa
     1501 atcgaagaac ttttggatat caagttagaa gtagattcta atgatcagcc atcagaacag
     1561 gaggcgtaaa aatggtacaa cgtttgagca aagcggagtt taaagagaaa tataagtatt
     1621 ctgaaagtac ttatcaaaga agaatgaagg aatttaaaaa atcacgtttt agtgaggggt
     1681 ataacgcagt tacttccaaa gaaataacaa ttgatgtcga tttatatgaa cagtttagaa
     1741 catggcgttc taaaaatcga tttagagtta gagctgtttg ttaatagcta aaaaatctaa
     1801 attcaccact tctgaaaaga ggagttgctg ctctcctttc aagtttgcca aagtccacgt
     1861 tttttcattt tggcaactcc tcttcttgga ggtggtgacg gcgagagacg aaggagggat
     1921 gacatgaagg aagaatcaaa aatagggatt ttgaatgaga acaattacac aagattaatt
     1981 attgaaacag aagaagggaa aaaagtagca gaagttacat tgaccgatgc aactcctgct
     2041 gacggttatc gtattcgatt aactcctaaa tatgattaac cttttggtgg gtgtggatcg
     2101 tttccgtgac tatcacggct ttgaattttt ccatctctgc catgaataaa tagctcagat
     2161 ccttgatttt tagaaatctc tctagcgatt tttactgctt ctgattttgt attagtatgt
     2221 gcagtcgctt tagaatttcc agcacctttg acattccaac caccattgga attaggtaca
     2281 acatgttgat tttttcccat agttttcacc tccatttcta tagaaatatt ttatcaaata
     2341 gaaatggaga aattcaataa acgaaaggag aagtgatatg gcatatacct tgcaacaaga
     2401 acatcaaatt ctcggtttga ttaaacaacg caggaaacaa ttacaagatg accgtgcagc
     2461 gcttagaaaa gccgatgagc tatcagatag gcaagctgaa ctaattgctt ctgaacttga
     2521 ggatttgaga atgctagaaa taaaaaatag ggagattaga ttatgaagaa gacagacaca
     2581 ctttttatag gattcatttt ggggttatta gtgattgtag cgcaccaaag tattatcggg
     2641 ggaagcttgt tcgcagcatt gatggtttta atcaatctgc ttgattcaaa agaaaggagc
     2701 aactatggca cgagaagaag cgctaaaaat cggtaaagtg attgctgata atcggtgggg
     2761 aaatagccgc cctattattt taagcaagca acatatcgaa aagcaaaaag catggcaaca
     2821 aataaaaaag tgactctgcc agccagcaaa gagtcacata caaatttata aaactaggag
     2881 aattatatca catgaataag aaaattgaaa atcttatcga agaattgaaa cgtgaatgcc
     2941 aaaagcaagg tgtttctatt atttgtacag cccaaaaaga aggggaactt aaaagtctcg
     3001 tttatggtga gacaacagaa attttacttt gtcttgctat gcaagaagaa catttagatg
     3061 aaaatctccc attgtcagca catattatgc gtagaattgc tgtggatgct tacgaacaag
     3121 cgaaaaatga agaagaaaat caaccttcaa atcatacttt tgttattaat aacaaggaag
     3181 atttagctga tgtgatgact cgtattctca agggggaatt tcaatgatga atgaaaaaac
     3241 aattgatcta ctcattattt tatttttcac gttagtgatt gtagcgaaaa gttatgtaat
     3301 ctttggcttg ttattcgcaa ttaccatgct tgtgctttgc gtgttagcaa gcagaaaaga
     3361 ggttaaacat gaacgagtta gcaaatcttg acaactattt aactgatcct gattatgcta
     3421 aaccaccata tgaagcacca attgatgagg aggatgaaga tgagtaaatc taccttagaa
     3481 atgagccatc aagaatggct tgaagaccgt aagaaaggca tcggaggttc ggatgttgga
     3541 acaattttag gattgaataa atggaaatct ccttatcaac tatggctaga aaaaacagga
     3601 caagtagtac ttgaagaatc aggaagtgag cccgcttatt ggggtaatgt tttagaagaa
     3661 gtggttgcta aagagtttca ggaacgtaca ggcaaaaaag tacgcagaag aaaccaagta
     3721 tttgaacatc cattacatcc atttttaaga gcaaatattg atcgggaagt agtgggagaa
     3781 aatgccattc tggaatgcaa aacagctaat caatttctcg gtaaagaatg ggaaggcgaa
     3841 gaggtaccgc ttagctatct ctgtcaagtt caacattaca tgaacgttct aaacaaagac
     3901 tattgttaca tcgctgtctt aatcggtggt caaaaattta tctggaagcg gattgaacga
     3961 gatcaagagc tgatcgatac aatcactgaa caattagtag agttttggga aacaaacgtt
     4021 cttggaggta tcgagccaat tattgatggt agtcaagcga cagctgattt cttgaaagag
     4081 aagtatgcag atgttgaaga cgttcaaacg acgttaccaa ttcatttcga tgaactagtt
     4141 gaacagaaaa acgaactcaa acggactaag aaagaaattg aatcagctat ccgtcaagta
     4201 gacaacgaga ttatcagcga gctaggtaaa cgtgaagcca gtatcggtat cactcaaaaa
     4261 aacatcatca gttggaaatt tgtccgtacg agacgtatga actcgaagaa actagcagag
     4321 aaatatccag atgtcgcaaa tgatgaagag atttataacg ttactgaatc aagaaggcta
     4381 accgaaaggg agatcaaata atatggcaac aaatgaatcg ttaaaaaatc aattggcagc
     4441 aaagccacag aaacaagttg caccaggtca attaggactt aaagctttga tgaatacacc
     4501 aacaatgaga aagaagttcg aagaggtgct tcatgacaat gctaatgctt ttatgtcgaa
     4561 tgttatgact cttgtatcta atgacagtta tcttgcagat agtgaaccga tgtctatcat
     4621 gagtggtgcg ttaactgctg caacattaaa tcttgggcta gataagaatt taggttatgc
     4681 atatttagtt ccattcaata gtaaaaacaa gcaaacagga aaatgggaaa agaaagctca
     4741 attcatgctt ggctataaag gatatatcca attagcccaa cgatcaggta aatacaaagc
     4801 attaaatgtg atcgaagttt acgaaggaga actaaaaagc tggaaccgac tgacagaaga
     4861 gtttgagttt gatccaaatg gtagaacgtc tgatgaagtc attggatatg ttggctattt
     4921 cgagttactg aatggattca aaaaaactgt ctattggacc aaacaagaaa tcgaagctca
     4981 tcggattgct aacaataaag atcgcgataa gacaaagtta agtggtgtgt gggcatctga
     5041 ttacaatgca atggcacgaa aaactgtttt gagaaatctt ctttctaaat ggggaatctt
     5101 gtccatcgaa atgcaagaag ccaccacatc ggatgagaga gtccaaaggg ttcaagaaga
     5161 cggcagcatt attgctgaaa cagaagttga agaagatatt cctgaaagaa aagaagcaga
     5221 ggttatatct gaagaaaatg aagatgtaca aactggatta tttgatgcat ctaatccgcc
     5281 gttaaacaaa taatgaggga gctttctccc ttgcttttct agaggagaaa tacgaatgaa
     5341 cacaggatat gtcaaattac atcgaaaagt gatgaattca ttcgtttgga ccaatcctta
     5401 tatgtataaa ttatggaact tgtgtttgat gaaagcgagt catgagaatc gcaagatact
     5461 ttttaatgga aaagagatac aagtgaacag cggagaattc gtcacagggc gcgatgctat
     5521 cacatctgag atgaacgaag gcgtgaaacg tgaacatcaa gtgaacagcg gttctgtatg
     5581 gagatggcta aaacaatttg aaaaaaacgg aatgttgaac atcaaatcaa ctacgaaata
     5641 cagcgttata tcaataaaaa actggtcttt gtaccaaagc agtgaacaac aaatgaacat
     5701 caaacgcaca acaagtgaac aacaagtgca cacaaacaag aatgaaaaga attataagaa
     5761 tgaaaagaat aataaaacat catcgtcgca accacgcaaa aagcgtgttt acgacaccga
     5821 ctcagtttac tacattctcg cggaggagtt attcaaacag atttgtcaga atcaggaaat
     5881 caaaaagccg aatctgcaaa gttgggcaga taacattcgg aaaatgatcg agatcgacaa
     5941 gcggaccgaa aaccaggtac ggggaatgat tgaatggagt cagcacaatg tgttttgggc
     6001 atcgaatatt ttatctgcta aaaaattgcg agaaaaatac gacacaatgg cagcgcaagc
     6061 caatcgtgat tataaaacaa aacaaactaa aacgcttgaa tacgagaaat ttagcacaga
     6121 tgagttgcct atttgagagg aggcgtaggc atggaaactg ttggggaaat catggaaaag
     6181 ctgatacaga aagtgcttgt ccaacgtggc gaatgtcctg aatgcggaca gcctttgtat
     6241 ggatggcgta cgaagaaccc tgatggctca gaacgttgta agccaacctg tatgcaatgt
     6301 gggtataaag cattgcgagt tcaggaagac ttacaaacag aacgaattta caacgagagc
     6361 ctgaaagcaa gagcaatcaa ttttttcaaa ggtggttctg ttgtgcctaa tcaagcgttg
     6421 tttgattgca cattgcagaa ttatcaaatt gtcgatcaag aaacaagaca agcggttgaa
     6481 gtaaccaaac gctttgttaa ttcagtcttg ttaggaaatc caagtcacct tgttttaact
     6541 ggaaaacaag gaacaggtaa aagtcaccta gcgatggcag cggcttggga agtcttgaag
     6601 cgatcaaact acgataaaaa aatcttattt atcgggttac aggaaatgct ggatcaaatc
     6661 aaattttcgt acaacaatcc tgaactcaga aaaacgattg agggatcgtt gattgcagat
     6721 atcaaaacag cggatttagt catcattgat gatatcggtt cagaactagg aaaagatgca
     6781 tcagatagtc gagcgtttgg cataaacacg ctaaattcgt tcttggatgc acgacagaac
     6841 ctagcaacga ttatcacaac gaacttgctt ggtgaagaac tgaaaaaagc ttacggtacg
     6901 agaacaatat caagaatgtt tgtcaactct gatggattta cgatggtatt ttctcaaaca
     6961 gcagacaagc gcataaaacc agtcaaagga gcgatcgcat gaatttgact aaacaagaaa
     7021 aaagaatctg tcgtcagata atgttgcaaa ttataggtga tcgtgacatg gacgaattat
     7081 ctcaacaaga gagtcgaatg gttcggaaga taagtaagct aattatttat cgggatacag
     7141 aaagatttct cactgtttta ggtaacgtct acgagaatcc agagttattg gaggtagagt
     7201 aattgccaaa aatattagat gcatgttgcg gtagtagatt gttctggttt gataagaaca
     7261 attctgacgt aacatttatg gattgtcgtc agcagtatga agaattatca acaggtcatg
     7321 tgatcaatgt tgatccagat gtggtcgcag actttcgcga tatgcctttt gaagatgatg
     7381 tgttcgatat ggttgtattt gacccgccac acttaagaca tgtcggcgaa aactcatggc
     7441 ttgccaaaaa atatggaaaa ttagacgaac tttggccaga agacatcagg caaggttttg
     7501 cagagtgtat gcgagtttta cgaccttcag gaacattaat ttttaagtgg aacgaggaac
     7561 agataccact ttctgatgtg ttagaggcta ttggagaaca gccattgttt ggtaataaac
     7621 gaagcaaaac acattggctt gtgtttatga aaaaattcag ctaacggagg aaacaaagga
     7681 ggaaaagtaa tgaagattgt attaaataaa tgttttggtg gctttgggtt gagccatgaa
     7741 gcaaaaatgg aaatttttaa aagaaaaaat attgaagtat tcccatacat caataacttt
     7801 agctatgact cagatgatga atacacgaga tacacaggcc aaaagctagg ttcgatggat
     7861 tttatctact atttcaaaaa agacccgaaa atcgacaaag ttacaggaat ttatagcgaa
     7921 attgaccgac tgtacggaat tgctgatgat tccagttttt caagtgattc aaacagaggt
     7981 gataaggacc tcgttgctgt tgtcgaaaaa ctaggaagtg aggccagtgg accatatgca
     8041 agtcttaaag tcgttgatat acccgatggg gctgagtggg aaataagtga ttatgacggc
     8101 gttgaaactg cacattatgg ttttcaaaca ggtagtattt agtccactaa tgacaactaa
     8161 agaggaggca gaaggatgag tgaagatgaa tactttgaac agtagtctat taacgacaga
     8221 gatttttaac tggaaagggg tgtagtcatg gacgcatcgg aagtagtaaa taaaattaat
     8281 agtctcaaag aggttttcgg agacgtcgaa gtagtgataa acgcacaagg ctatgacaac
     8341 ggatttttta agcagattac cgacattagc attcagcaag gaatggaaga cgaagatgga
     8401 aactttatcg atgaagtagc cattttagtg acttgcgagt aagtaattga cagctaaaga
     8461 ggaggcagaa ggatgaaaaa attgcaccaa ctcatatctg agaaagaaag cgaactccaa
     8521 aatttagaag atagtttggg attggggttt ccaattgttg agcaagctaa aatgactcaa
     8581 atcagtcatc tacgacttga attggaagat ttaagacaaa tagaaaaatc aattcaactc
     8641 aacgacaacc agaaaatcgt gttggagtgg ttgaaaagcg agacaatttt aactagagaa
     8701 gcaccaatat tatctgttaa tgctttttct gataaaaatt tactaggaaa attacctgat
     8761 aaagtacgca aagcttataa actattggct tgtaaacaag aatatgaagt cctatcagca
     8821 ttcgctcaat ggggattaga acaggaggaa gcggaatgaa caacagacat cgcagaataa
     8881 caaaactaag aaaacaggaa ctgaatgtac taaagacaaa gtttgaaaaa gaatatggaa
     8941 tttcagcaga agaaacatat aaagtggcaa gtcagtttgt tgctgatgcg agtaatgcta
     9001 ttcgtaagtt tgggatttcg atattaaatg atgatcgtaa atgggaggaa atgagatgaa
     9061 aataaaagac ggattttacg ctagtagtca tggtatcggc ggtttaatgc tagacatgcc
     9121 gataaagaac cctaaaacac gtcagaaatc aaaattcaaa atcggtgaca tggtccgatg
     9181 taaagcagaa gagttcatct atccgtttcg tggatatgta gagcatgtct ataatcattc
     9241 agcaatcatt cacattgaaa acacgatgga atgcgataag tggttagcga aaagcaaaga
     9301 taatttagca gtggctcgtt tggtggatat ggaactaatc aatgacaaat aaaaaagccg
     9361 gatcgctccg actgattcaa taaatccaac acatttatta tatcacataa aggagcggtt
     9421 tgacttgatg caattgttac gagaggtaga tttcaaacag acaagatgta atgcgagaga
     9481 tgtgctgaag aactttcggc gtttggagcg gatggcaggt cgctctttga tagatattaa
     9541 gtcgccgatt attacggata tgccgaaggc accgaagcac ggcaataagg cagaagacgc
     9601 gatcattcag atgatggata tagaagcgga gagagacgca atactagcgg ctttgatggc
     9661 tcttagtctg attagccgtc agatactcta ctacagcttc tgtgacgtaa acaagcactc
     9721 taattatgaa atagggcaat tgatacgagg atacggagag aagaatgtag agaagttgaa
     9781 atccatcgca ttaatcgaat ttgcagaagc atacaaaaaa ggcgtgttag ttcagtatcg
     9841 ttgattttgt agggtttttg tagggatagt gtagggtttt tgagcggttt aacgtgatat
     9901 tatggtagtg tcgaaagatt agtgataggt ctgagacaaa ataaaatgta agggaggaaa
     9961 tctccctcat cgttttaact taagcttcga tagacagcaa cggaaatatt aagaataagg
    10021 atgtgaattt caactccttc taaattgttc ttattatcta tcatccgttg ttgtctatta
    10081 atttatgcat cggaggaaaa acgaatggat aaagaaatca aagtaactgt caaattagat
    10141 ttgactgaac taaaagaact gctcaacaag gctagtgacc aagtcgaaca gttacaagaa
    10201 actttagatg aaattgctaa ttttaaaatc caagtttctt agcagtatat tttttagcag
    10261 ctgcactcat aaaatcatac caagtatcag aaaaatataa cttaactaaa taattaaaaa
    10321 aggtgggtaa atagaaatga cggcgttaat aatttcaatt tttgcgctct gtcttaatgt
    10381 ctatatgatt ggatttaaaa atggacaaaa taaaaaatag tagcagccga gaataatttt
    10441 atagtgtcac tgtggcggaa atagaagacg caaaggtgga ggtaggaagc gtatggcgca
    10501 ctatcgggac cttgtacaaa actagaaagg actagtacgt gtgtggtgcg agccctaggg
    10561 aggaacagga taaccgcctg tgtgtaggtt gctattacat attagatcac tctttgagtg
    10621 gtctttttat ttacataaag gaggctacat aatgagaaac tactggtata tatcgctaac
    10681 taatgaatat cctcgaacca ttgatgattg ttcagtgcgt gttgtgcgtt ctgtccaaat
    10741 caaaaagaag tactccattg ttgaaatgac cagagaagct acgccaaaag agattgataa
    10801 atgcaaactt ctttattgcg gtcatggttt ctatgatgaa ccaaacattc aaaataatat
    10861 taacaagaat ttgagggatt agaatgcaag aaatggctta aaaatctcca atcaggacaa
    10921 atcaagttag acaaagtttc cgatttaaag atattgattg aagctgattt aatgctaaaa
    10981 gatattgaaa attagaaaac aaaactcaac ctaagaagat tgcgaggtgg tgtgtattga
    11041 atggcaagac aacgtgatcc aagacgtgat gaagccaaaa gaatttggtt agaatccaac
    11101 ggagaaaagc agttaaagga aattgcatct gaattaaatg tttcagattc tcaggttaga
    11161 aaatggaaat cgcaagacaa atggagcgct gaattgaaaa gtaacgttac caatggcaaa
    11221 agtaacgtta ctaatcaagg tggcgctcct attggtaatc aaaatgctaa aggtaacaaa
    11281 ggaaacagca gagcatcacc gccaaagaga aataagaatg ctcttaaaac tggtgagtat
    11341 gaaacaatat tttttgacac gttaaccgat aatgagaagg acatctattc tagtttgaat
    11401 gatgatcctt cttttgcttt gtccgaagaa atacgacttc ttaaaataag acaacttcga
    11461 atgatgaaaa gaatccaaca agctgaagct ggactaaatg atgaagaagt cgaacgattg
    11521 cagcagctaa gaaagattaa aactccgatt gaaaaaaatg gtaaaaagct agaaatcaag
    11581 cgtgaggtta tgcaagatgt gcagattagc agaaaaaaac atcgcaaaat tgatgatatt
    11641 ctttcaattg aagattcatt gactcggatt agcaaccagt tagctaaagc catcaagcaa
    11701 atgaatgaac tttatatgaa tgaatacaga actgatttaa ttaaagctca gactgataag
    11761 atccaagctg agacaaatga aattggcgga aataattcag gtgaagaaat agaagaatgg
    11821 aaacaggcag ttttaaatgc cgcaaacaaa cgggcggtga aagaaaatga ataatgaatt
    11881 tattcctttt gctgatattg gttctgccat tgattattac tatgataaac cagtagcttt
    11941 ttgccaagat attttgcatt tgaatcctga tgaatggcaa gaaaatgttt taaatgattt
    12001 agctgaattt tcaaaggttt ctgttcgttc tggtcaagga gttggaaaaa cagcattaga
    12061 agcaggagca atactttggt tcttaacgtg tcgaccctac gctaaagtaa tagcaacagc
    12121 tccgacaatg aagcaacttt acgatgtact ttgggcagag gtagctaaat ggttaaatga
    12181 tagcttgatc aaaaacttac tgaagtggac aaagaccaaa atttatatgg ttggtgattc
    12241 agagcgttgg tttgctacgg ctagaacagc gactaaacca gaaaatatgc aaggttttca
    12301 cgaggaccat atgttgattg tggtagatga agcttctggt gtgtctgatc caattatgga
    12361 agctattctt ggtacgctat caggttttga taataagctg ttgatgtgtg gaaaccctaa
    12421 taatattgaa ggtgtctttt acgattccca caattcagac cgtgataaat acagagttca
    12481 taaagtatca agctatgata gtaaacgtac aaacaaagac aatatagaaa tgattcttaa
    12541 aaaatatgga aaagaaagtg atgttgctcg tgtccgtatt tttggagaat ttcccaaagg
    12601 tgcgttggat tcatttatca gtcttgaaac ggttgaattg gctacagaaa aacaaattag
    12661 tgattcttta gtcaataaaa caacggttgc tcatattggt gttgacgtag ctcgatatgg
    12721 tgatgattct acgattctct ttcctagaat tgctaccagg gcattggagt atgagaagta
    12781 ttcaaaacgt agcactatgg aaacaacagg atatgtcatc aacatggcca agaatctaat
    12841 gagtcaatat ccgagtattg ataaagtgat gattaaagtc gatgacactg gtgtcggagg
    12901 tggtgtaacc gaccgcctag aagaacttat agaagacaag cattatcctt ttgaggtgtt
    12961 tggagtgaat aacggttcaa catcagaaga cgatttttac gataatttag gtactcaact
    13021 atggggaaac atcaaggaaa tgttagaaga aaatatgaca gcaaatctta acggagaaca
    13081 gcctgttatt gaattgcctt ctgatagttc gttaatcaaa gaattaagta ctcgcaaatt
    13141 caaaatgaca agtagaagtc gtatacgttt agaaagtaaa gatgatatga aaaagcgaaa
    13201 tattggtagt cccgatattg ctgacgcact ggctttagcg ttttatgagc caccaagtca
    13261 ctatcaattt attcaatttt aggaggtgag tttttgatta gtacagtatt atctttagag
    13321 agatataaga agctacgtgt taaatatgca acacaaattg aagatggaat gtttgatccg
    13381 aatggtttta tagaatatat gaaaccattt tttgctgatc gcgaaagaaa atatctagct
    13441 tatactagcg aaaagaatga aatagacaat agaccaaagc ctaacactga tattgtaaaa
    13501 gttaataata aacttcatgc tggtatgtat tcaattgtcg tagaccaagc agtcaatcat
    13561 tttactggta tacctatcaa atgggattac gatgtatcgg aacaaaaaag aacactcatt
    13621 caaagattaa aagataaatt cttaaaaaat gatatagaac ttccaacagt tccagaagct
    13681 tttaacaaat taacaagcaa tcttgattcc atgagattcg caatgcttga ttctgaaact
    13741 gcaacttttc aaggagcttg tggagtagct ttccgattgt tagagcctgt ggaagaagat
    13801 gatggttgga agttaagagc aagtaatatt gaaccttgga gagcagaaag atatggaaat
    13861 gccggaatct atatcaaaga aaagtatgac tcttaccaga aaaaattttt tcaagaaatg
    13921 aaagttatga caagaaataa aattctgaca tatgcttgct atggtgattt gaattttgtt
    13981 acaagcggaa cgttcaaaaa aattgatgag accgataacc ctttggggac gattaccttg
    14041 gcagaattta aaaataatac gaatcgttat tgtgattttg aagtagctga ggaaattgga
    14101 gatgcaattg atcgtgcttt gtctgatcaa caaaacgaaa tcgaacaatt taagcttgcg
    14161 tacatgcttg ttactggcac aacaatgagc aaaggcactg ctaaagaaat gatgaatcag
    14221 ctagggatta tcaacttaaa agaccctact gcaaaagctg aatatgtcac aaaaaaatta
    14281 gcaaaagatt tcaatgaata tcatatggat ctattgaaaa aacagtttta caccatttgt
    14341 aaagcaatcg attttaacga tgaggtgttt aaatcaaaca gttctggaga agctcgcaag
    14401 tggcaaatca ttagcctaga agcgaaaaca aatactaaag agcaatattt tagagaagga
    14461 ttgaaagaat gcgcagaaac aattgctgct tttcttaagt ttcatgacaa agtagaaatt
    14521 gagcctgaaa aaattatttt tactttctct agatctttgc caactgattt aagttattta
    14581 gctgaagctt tacctaaact tgcaccatac gtatccaaac gaactattca gagccaaatt
    14641 ccatttgtaa cagatgttga ttatgaaaat gaaatgatgg aattggaaag tggaagtgct
    14701 tatccagata gtgaatacaa ttttggcgga ggtggcaata gtgacgatag aaacgaagta
    14761 ttggaccaaa cgtcgagaac tggaggatca agcaaggctc aaacaagaaa atcagacact
    14821 taaaaaatta actagtgtat ttcctgaagc actgaaagag atacaagcaa aactattatc
    14881 acaagctgac ttacacaata tcacttatcc agaaatgatg gagttttaca gtacaagtaa
    14941 tcagaaaaaa tatcgtgaat atgtggaaaa aaattataag tcattaaaaa tgtatgatgc
    15001 aaaatacaaa gagtttatcg atgaattttt tccaccattt gactatgcaa aagtcaatcg
    15061 cttattacaa atacgatcag atgtatttaa aattcttgca gaatatgcga tggatgcaga
    15121 tgtgaatcaa tatttttctg atcgcttaga ggaaattctt caaagaacat attcttctaa
    15181 tgctaatgtt tttgttcaac ttttaaacgt tgatatacca aattatttac cagaaaatga
    15241 aattaaacat tatttgaact atccatggtc aggaaagaca ttttcaagaa gactttgggg
    15301 aaatatttca tcgcttgaac agaaactctc taatgctatt gtaaaaagtg ttgctagtgg
    15361 agaaggcgtt atacacgcat taaacaccat gagattagac tcagaaattt gtgacatgtt
    15421 taagttagaa gaatcaaagt ataacaaagc gatagaaaat ctcgttcgaa cggagtatgc
    15481 aaaatttgca caagatggta ttgaaaaatc atatttagaa acaggtattg aggaatacaa
    15541 cgtattgact gcaaaagatg agagagtttg ccggatttgt ggaggaaagg caagtaagaa
    15601 tccctataaa ctgaaagatg ctgtcatagg tgaaaatcga gcacctttcc atagtcgttg
    15661 tagatgtacg gatgttccta atttaccaaa attaggaaag gatattgatg aagaatatga
    15721 ccgtttattt ggcgatttat tagatgagtt tgcacatgat tcttttggaa ttaatttgaa
    15781 acggaggaag tagaatgaaa gatttttttg aagcagtact aacaattaat gtaaatgctg
    15841 atattgcaga agcctacaaa acagctattg agtctgagaa ccatcctaat ggcttgagag
    15901 accattggaa tggcaattat gcctacgtgg ttattggcga tcaaactgtt aattatcaag
    15961 ataatactcc agttgataag aataccgtta atttaacgat tcaattatta tctcattcat
    16021 taccaaattt aaaagaaaca gttgattggt atgaaaagat gggatgtatt gttgttagaa
    16081 ctgactacaa agaaggaaag tctagtaatt aggctttttt attttgtccg aaatgacgtt
    16141 aaactagcgc aatactgggc ttggttgaat ggtggggcgc aactattaaa actcaaagca
    16201 atgcggggcg tgaaaacgaa tcgtggggcg aaaggagaat gagcatgaaa cacaaatcat
    16261 taatgccaat gaatttgcaa tactttgccg aaggtgacga tcaaaagttt tcttttgatg
    16321 acttcaaatc ttttgtggaa tccaatgaag aagctcaaaa atttattcag tcacaatctc
    16381 aaagtgttgc cgacaaacaa ttggaagctt ggaaacaaaa taacttagat aaaattaaac
    16441 aggataccat caaggaatat gaggaatcta agaaaaacaa gtcacctgag caaattcaac
    16501 tggaaaaact acaagctgaa tttgaagcag aaaaagcgtt gcgtgtgaca agtgataata
    16561 aagcatttgt tgcagaacaa attgctggat tagaactaga tggagagtta aaagagtcta
    16621 tttctcaatt tatgctaaat aatcttgtta gttcggatac agatttcact aagaatgctg
    16681 ttgaaggttt tacaagtgtt ttgaatgcaa ttaatgagaa acatgcagat gcattaaaag
    16741 aactacaaat gaagtctgca tttggtggaa ctcaacaatc gaataaccag gttcagcaga
    16801 acaatgaaac attaacaaat ccagaagaac aattaggaca aattcttcaa caatttaact
    16861 aggagagtga aaaattatga aaaaaacatc tttaaataat ttagagtatt tggatatttc
    16921 accagcgatt aatgctatgc aagtaccaaa tacacctttt ttaagctatt tacttggtgc
    16981 tggaaaaaca gagccagcaa actcgacaga aattaaatgg cgtgaatatg atatcaacaa
    17041 cgatgattct tctgaaaaac ttgagggcgg agaatatcca gatgctgaat caggtcgaac
    17101 ttggtttaac aactatactg aaatttttag aaaatcaacc tctgtatctg gtacattaga
    17161 tgctattaat gtgaatggag tcggaaatga attaactaat caagtagcac tacgtggtat
    17221 ggaaatgaaa attgatttga accgaaaatt gattactggt gtaaaagctg atgaaaatgg
    17281 ttctaaaggt cgtcgaatga atgggatttt gaacttgatc aattcagcaa ataaggcaga
    17341 aacagccact gcgggtgcag taacaagaaa agatatcgat actttattta aattgatgta
    17401 tgaaaaaggt tatatgggag aaaaactatg cttgatttct ccagatatgc aggagttaat
    17461 gactgatgag ttagatggaa aatcaacaaa aattgttcag ttcggggaaa gagtaacttt
    17521 tggattgcaa attggaaata tcgtgtctaa ttacggtaca ggtattgctc tactagaacc
    17581 atcattgcca aaaggaacaa ttgccgcaat cgatactaat tatgtgaaac tacgtccatt
    17641 acgtgaatgg agagcagaag aacttgcaaa aacaacggat tctagacgta tcggtcttgt
    17701 aggtgaatac tctcttgaat acaatgcttc aaactctggg gcaattttaa atttaaagtc
    17761 tgaataaaag ggagttagta ctcccttttt tgataggagg aattacagtg gtaaaaaaag
    17821 atgaaactaa aaaagatgaa gtcgtgaaat atagagtagg taaaactaaa aattttgttg
    17881 ggtttgttca tcctaaaact cgtagattta tcacagcaga ttcaaataac gaatttatca
    17941 tttctataga tgataaagaa gcaattgcaa ttttggaaga tgcaattgat gttaatgaaa
    18001 tttaggaagt gatctgatgg atgaatcgct aaaaacggaa atcattgagt ctacaaaaga
    18061 agattttcca gatttgagtg aagaacgcat aactaattta ttagaaataa ttttgctaga
    18121 aattgaatca tacaacactt gtaaaaatga tatttcatgg gaaaagttaa aaagcgtgat
    18181 tagtgaagtg ttgtataaaa taataaaaaa tgaatcagaa aaaacagtat cttcagttag
    18241 acgtggcgat acaacgatta gttatgcttc aacaacaaat gatgttagtg agttacttct
    18301 aggctatggt gatttgatac gaagagttat tggttgtgga ggattggagt ttttttaatg
    18361 aatgaagcag atattttaga aactacttat gaagatagtt gtattattga aagactgacg
    18421 gacattgaag attctaatac aaatattact attcaagatt acaaaaaagt atatgataat
    18481 cctatttctt gcgctctttc acaaggtcaa atcgatggac tagcagtcat agaagatgga
    18541 gagatggtaa atgtttcaac tgacacatat aaattatttg ttcatcctaa gattaaacta
    18601 aaaaaaggag atcgaataac aataactcaa aaggccagtg gcttaatttt ttctctattt
    18661 gctactaagc ctttttacta tcctagtcat tgtgaagtga atttgatagg aagtgagaaa
    18721 aatgggtaat ctcaaatatg aatcaaatgc agaaaagatc attgagaatt ttaaaaatat
    18781 gactgtaatt gctcaaaaag aaggaatatc cttcgttaac gattcaatga ataaagtcgt
    18841 tagtttagct aaaccattaa ctcctgtaaa atcaggtaat ttaaggcgag gatatcgtgt
    18901 agtaaaagct agaaaactat caagcggtcg aattgttgga gcagttataa acaatgaaca
    18961 ttattttaaa tatgtagaag aaggtcatag gactaaaaat ggtggctttg tcaaagggaa
    19021 attcatgtta actcgtgcaa cgaatcttgc aaatatgtct tatattcctc gaagatttaa
    19081 acaaatggca ataaaaatcg ttaagaaagg aaagtaacat gaaagatgaa atcattgctg
    19141 caatcagtag caaattaaaa gaaatctatc ctgatgggac aatatatctt gattcagtta
    19201 tgcagtcaac taaagatttt tatttcgttt tatcagtaat ggaatctgga actgaaaatg
    19261 taggaattga tattcaaaat gtttctttct taattgatat tgcattgatt gataataaac
    19321 ctaatagaaa tttaattaat gaattagtct cacgttgtgg gacttttttt aatacgatta
    19381 caatcgatga gcaaatatta tttccaaaag cctatttacc tgatgaagca gatggtgttc
    19441 aacatattcg ttttacatta gaatttccac aatatattga atggagtgaa agataaatgg
    19501 gagaaaaaag aagtaaaacc ggaattattt ctgtcgaaaa acctacttgg tttcctttgg
    19561 aagatgagac agggaatttt ccggtatatg gtactgcgtt gccaatggga acagcagtaa
    19621 gtatcaaacc aacagctaat tatgaaacaa cacaagatta tggggattca gtggttcaag
    19681 atcaatttac agcttttggt ggtgcagaag ttgaactgga agcaaatgga tatactcata
    19741 aagttttatc tacaattact ggagggaaaa ttgttaaagg tggtgccttg cgttctggag
    19801 aagatattgc gcaagatggt gcgtttgcat atagacgtaa aaaatcgaat gggaaatacc
    19861 gttatacggt cttttataaa ggacagtttg ctctagattc agatgaaaca tcaacgattg
    19921 aaggaagtaa agtaagtttt actcatccaa cttggaaggg ttcatttgta gatgtaccag
    19981 gacttggata tatgtattca gttgatgaag atgatgaagg cgtggataaa gcaatgatcg
    20041 gaaattggtt tacaaaagta gcaattccaa ttgaagaagc agaactttca ggaggtacag
    20101 aataatgtca aaatatcaaa caacgattaa attaacgaaa aaagatgaag aaggtaaata
    20161 tgagcaagta caatttaaat ctgctgaatt tctaccaggc ccagtcgtag aagaagcagc
    20221 agaagtaatg gagggaatgc aaaatgctgt agatggaaaa tcagtatcag aagcattaag
    20281 tcgagcttat tcatttattg cagatatttt gtttgaagga cagtttactg gtgaagatta
    20341 tcgtcaaggg atcgatgctc gagaaattgc ttcgttgaca ggtaagttat taaaatctgt
    20401 tactgcaggc tttgatgaaa cttatacaga aacgaaaaaa aagtaagcga agctctcaga
    20461 tatccttttt ttaaacattc gattacttat cgagaattag atttaaagac gcaattactc
    20521 gaagcaggtt ggacgttacc agaaattgaa cgtactgact ttgacgagtt aatgcgtctt
    20581 tttgcttttc gagatgcagt aaaagagcat gaggatgttg agtactacga taacttcacc
    20641 caattttagg aggtgatact ttgaataacg atgacctaat tctgaagatg atactagatg
    20701 aatctggttt tactgccggt atgaataatg ctgtcaaaaa gttgaactct tttgatgaaa
    20761 caatcgaaag aaaaagtaga aatagtggca gttcattagg tagtatttgg aaaatatttg
    20821 ctggaagttt tctagctagc ggagtaacta gaatcgtagg agctggcttt gatctaatca
    20881 agggttccat aagtggagcg gttgatcgag tagatacgat gaataacgct ctacgaaatt
    20941 tccaaaatat gggatttagt aattcagaaa ttatgaagaa tatcggaaag aatgggcttt
    21001 tatctcaagg tattcaagga cttcctactg ctttgaatga tgcgataagt catgttcaac
    21061 ttcttgcttc ttctacaggt gatttaactc gttcaactca aatatttaaa gctttaaatg
    21121 atggaattct tggtttcggt ggttcaactg atcaagttaa tgaagctgtt attcaattat
    21181 ctcaaagttt ctcaaacgga aaagtagacg cacaaacttg gaactcaatg atcaacgctc
    21241 aacttggacc tactctttct gctattgcta aaaagatggg aattacaatg ggagatctga
    21301 aagaaggttt atctcaaggt aagatttctg ttgaagaatt ccaaaatcaa ttaatagaaa
    21361 tggataccaa aggtggcgga ggacttaaat cattaagtca aatcgctaaa gattctacta
    21421 agggaattaa aacctctata caaaatgcaa aaacagctgt tacacgtggt gttggtgagg
    21481 taatagaagg attaaataaa gcattagtag attcagattt aggtggattt aagggaatta
    21541 ttgataaagt gggcagttca atggaatcgt tcttaaaagt aattgctgca aatattccta
    21601 cagcagtatc atttttaagt aatttattta acgaaattca aaaatttggt tctgctttga
    21661 aattcatgat gccctttctt gttcctgcag ctaccgcttt tggagcgttc atgtttcaac
    21721 ttaaaggtat accagcaata ataaaaagct tcaataattt taagaatgcc ataattggcg
    21781 ttggaaattc attaaagatt atgggggcaa tagctgctgc taattcattt gttttaatta
    21841 ttggtgcagt cgttggtgca atagctgttt tcggttactt tatggcaacc aatgaagagc
    21901 ttagaaacaa ggttatatct atttggaatg atgtgaaaga ttccgtaatt ggtgtattaa
    21961 aaaatataaa ggactgggga attgatactt ggaattctgc taaagaaatg gcatcaaatg
    22021 cagttgaggg tgtcaaagat gcttggtcag gaacaaagga atggttttct aacacctgga
    22081 aaggtattaa ggatggggcc acaggtttat ttgataaaac agtagagact tcaagaaatg
    22141 cagtcgatag tgtaaaaaat gcatggtcta atatgaagaa atggttttct gatacttggc
    22201 aaagtataaa agattcagcc agagaaaaat ggaatggaat caaaggttct attatgtcag
    22261 ttgctggtcc attgattaca ggtataaaga atgcattttt acatgttact ttttatctag
    22321 agaccttatg gaataattta gttgagattg gtaaaaacgt ctttgagatt ttaaaaaatg
    22381 ttatacttgc gccggttttg tttattacct ccatgatttc tggtggatgg gaagaaacaa
    22441 aaaataatat gattgctgtt tggaataata ttaaagaaag tgccataaat atttgggaat
    22501 ctataaagaa tatatttgta agttatttta caaatattta ttttgctgca ctcaatattt
    22561 ggacagggtt caagcttaca ttgataaata tttggaatga agtggtaaat caagctaaat
    22621 cgatttggtt aaacataaag tattttttta ttaatctttg gattgatata aaatattttg
    22681 caattcagaa atggattgaa ttgaagtttt ctattattca aacttggatc gatttaaaat
    22741 ataatgccat tactacttgg aataatatta aacagttttt caaagatact tggaaaaata
    22801 ttaaagatac ggcatacaat acgtggattt ctataaaaaa taccatgatt aatacatgga
    22861 ataacattaa ggactctttc tggaatattg ttactggaat tgttaattct gctgaaaatg
    22921 catggacaaa tctaaaaaat ggtgtttcaa atgctattaa tcgggtaaaa gaaatcttta
    22981 attcgttaag ggaagtcaat ttatttgaaa ttggcaagaa catcattgat ggacttataa
    23041 atggtgtaaa agaaaagtgg aatgctttga aagatactat caaaggtatt gcaggtaata
    23101 tcaaaaattg gattaaagga gctttagata ttcattctcc atcaagatgg atgcgtgata
    23161 tggttggtaa aaatattgtt caaggtatta tcgttggtat tgataaagag caaagtaagt
    23221 tagatcaaac catgacaaat ttagtaaaaa caccgtctgt tcaacctgta gtaaatggaa
    23281 taagtcacct accaattaca caaacaaagc aaaatatatc tgctagtgaa acaaaagaaa
    23341 ttcatttaca tttaaatgtt tatggagatt tacctgattc aatggttcga aagattacta
    23401 caaaaattaa aacagaattg acaagacaaa tgaaacgaga tgctggtgca gtaggaggaa
    23461 cattatatgc aacttaagag aggacaattt tttattaatc aacattattc ttctgaattt
    23521 aatgtgtata ttcaaaacag gcctgcttct gtttcagcta gtcgagtaat tgaattgaga
    23581 gagcgagaag gaaatgattc tatcattatt gataaaggct attacaaaaa tgtgactaga
    23641 aagattgagt gttactataa agcaccttca attgatatgg tgcaggagtg ggaagatcga
    23701 atcactgaat ggttagatat gtcgtcttat agtgatttta ttctttacta tgatgaacaa
    23761 tatatttatc aagctgtagt aatagaagga cctgaattta aaggaacaag aaaaacagga
    23821 aatattgtcc cttttgaatt tacagtgagt attcgaccat ttaaggaaaa ttacaatggt
    23881 agatttacta ttcgacaaac agaaactttt gaaatttata acccagagaa gtattcttca
    23941 aaaccgctta ttaaattgag tggttctgga gatgcttctt tttatattaa taaggataaa
    24001 tatgatttga aatcgttgga cagagaatta tttatagatt ctaaattaga agaggcttat
    24061 cgaaaattag atggtaattt agaacatcag gatcaggtca ccttattttt agattttcca
    24121 tttttatatc ctggaaaaaa tgaaattaaa tggacgaaaa atattcattc atttgaaata
    24181 atgcctaggt ggtggagaaa agtatgaaac caagaatata tagtcctact gaaacagatt
    24241 tctcaacgaa tggcttagga attttaaagg attgtacaag atgtgaaata tatgaagtag
    24301 ctaatggaaa atatgaatta gagttggatt atcctttagg aactagattt gatgaatatt
    24361 ttgaaaatga ctatcaaata aaagcaaagc caaacgatca agaagagtat catatctttt
    24421 ttattgatga taaagatata gatacttttt taaatacagt aactatttat gctcagagtc
    24481 gtacaaatcg acttggaaga cgggtagtca ctcttgtgga agtggactct aaaactggtc
    24541 aagaagcgat atcaattatt gaaactaaaa tggataaaaa atctgacata cgactttatt
    24601 ctgatattac ggctgtttct agcacaatct ttgaagcgag aaatgtttta aattgtattg
    24661 ctggtgaaca aggatcattg cttcaatatt ggggcggaga aattaaacgt gaaccattta
    24721 agctttcttt gttaaagcga agaggtcgca ataatgttgg aacgattcgg tatggaaaag
    24781 atatgtctgg tttgaaggtc aaattagatt ggacaggtat aaaaacaaga attattccat
    24841 atgctgatcc tcaaagtgaa gtaggtacga ctaatcgaat ttatggttcg ccagtagata
    24901 gtgcctatat taataactat cctgatgtct atacagaaca tgttcagttt acagaagaac
    24961 aaggagtaaa agacattaag agcttaaata aaatagctaa aaattacttt aaaacgatca
    25021 atcctggctg tgataagcct aaagtttcta ttacggttga atttgataag ttgactgata
    25081 gtgaagaagc gaaagaattt gcgaagatta gaaattatgg tctgtttgat acatttaaaa
    25141 tatatcataa aaaatataat atttatcttg aatcaaaggt tagtggacta caatacgatt
    25201 ctttatctga aaaaactttg aaattagaag caggagacat tcaagttgct ttttatcagc
    25261 aacaagctgt aactattcag gataaattaa aagattatgc aacgaataat tatatgagtg
    25321 attttaatga ttatgtttct tcaatgatta caggtcaagg cagtgcagga ggatatgtag
    25381 ttttatggcc aaaagaaaaa ccttccaaca tctttattat ggataatcca gatttagaaa
    25441 aggcaagaga agtactaaga atgaataaaa atgggattgc tttttctaag aaaggatggc
    25501 gggggccttt taattcagct tggacattag atagtatatt taatgccaat tttatacaaa
    25561 ctggattaat caaagcagat atctttcaaa attcttttaa caagactgga gatgtattga
    25621 aattagttaa tggactactc caaatttgga acaacaaaaa gaaaataatg gagttaacta
    25681 aaaaaggaat ggaattttgg aattctaagg gttcaattgg aacgattgga acaactgatt
    25741 ctgttggtaa tccttttcct ggggcttcta ctccaacccc tattgaagat aattctttag
    25801 ttattcgtac aaatggagac ggcaaatata ttttgatttc tcctaaagta ggaaaaggat
    25861 tagttttatt aggaaatggt aaagcaattt attttggaga cttagatgta caaggaaaac
    25921 ttacagttaa aggaaaagaa ataattcctg gacaaggtgg tggtccatcg ggaggtggag
    25981 aatctactgg tgggtatcct agtgaattaa aaacagatgc agaaaagaga gcttggagaa
    26041 t
//
LOCUS       DAFLWZ010000035        25767 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000035 DAFLWZ010000000
VERSION     DAFLWZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.035"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1835)
                     /locus_tag="L1V38_001551"
     CDS             complement(<1..1835)
                     /locus_tag="L1V38_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316104.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="L1V38_001552"
     CDS             complement(1832..2536)
                     /locus_tag="L1V38_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316105.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="L1V38_001553"
     CDS             complement(2548..4857)
                     /locus_tag="L1V38_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1316106.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="L1V38_001554"
     CDS             complement(5052..5516)
                     /locus_tag="L1V38_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316107.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="L1V38_001555"
     CDS             complement(5516..6142)
                     /locus_tag="L1V38_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316108.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="L1V38_001556"
     CDS             complement(6149..6514)
                     /locus_tag="L1V38_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1316109.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="L1V38_001557"
     CDS             complement(6504..6842)
                     /locus_tag="L1V38_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316110.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="L1V38_001558"
     CDS             complement(6832..7158)
                     /locus_tag="L1V38_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1316111.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7139..7417)
                     /locus_tag="L1V38_001559"
     CDS             complement(7139..7417)
                     /locus_tag="L1V38_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1316112.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7419..8783)
                     /locus_tag="L1V38_001560"
     CDS             complement(7419..8783)
                     /locus_tag="L1V38_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1316113.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9365)
                     /locus_tag="L1V38_001561"
     CDS             complement(8796..9365)
                     /locus_tag="L1V38_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBN1316114.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="L1V38_001562"
     CDS             complement(9337..10524)
                     /locus_tag="L1V38_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1316115.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="L1V38_001563"
     CDS             complement(10588..12315)
                     /locus_tag="L1V38_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1316116.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="L1V38_001564"
     CDS             complement(12312..12764)
                     /locus_tag="L1V38_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1316117.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="L1V38_001565"
     CDS             complement(12876..13256)
                     /locus_tag="L1V38_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1316118.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="L1V38_001566"
     CDS             complement(13253..13639)
                     /locus_tag="L1V38_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316119.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="L1V38_001567"
     CDS             complement(13641..13919)
                     /locus_tag="L1V38_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316120.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="L1V38_001568"
     CDS             13967..14695
                     /locus_tag="L1V38_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBN1316121.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14826..15302)
                     /locus_tag="L1V38_001569"
     CDS             complement(14826..15302)
                     /locus_tag="L1V38_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBN1316122.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15262..15609)
                     /locus_tag="L1V38_001570"
     CDS             complement(15262..15609)
                     /locus_tag="L1V38_001570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316123.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15596..15781)
                     /locus_tag="L1V38_001571"
     CDS             complement(15596..15781)
                     /locus_tag="L1V38_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316124.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15782..16054)
                     /locus_tag="L1V38_001572"
     CDS             complement(15782..16054)
                     /locus_tag="L1V38_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBN1316125.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16051..16254)
                     /locus_tag="L1V38_001573"
     CDS             complement(16051..16254)
                     /locus_tag="L1V38_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316126.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16379..16591
                     /locus_tag="L1V38_001574"
     CDS             16379..16591
                     /locus_tag="L1V38_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316127.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16624..16818)
                     /locus_tag="L1V38_001575"
     CDS             complement(16624..16818)
                     /locus_tag="L1V38_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316128.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(16831..17013)
                     /locus_tag="L1V38_001576"
     CDS             complement(16831..17013)
                     /locus_tag="L1V38_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316129.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17010..17150)
                     /locus_tag="L1V38_001577"
     CDS             complement(17010..17150)
                     /locus_tag="L1V38_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316130.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17640..18005)
                     /locus_tag="L1V38_001578"
     CDS             complement(17640..18005)
                     /locus_tag="L1V38_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316131.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18045..18347)
                     /locus_tag="L1V38_001579"
     CDS             complement(18045..18347)
                     /locus_tag="L1V38_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1316132.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18347..18646)
                     /locus_tag="L1V38_001580"
     CDS             complement(18347..18646)
                     /locus_tag="L1V38_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316133.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18639..18803)
                     /locus_tag="L1V38_001581"
     CDS             complement(18639..18803)
                     /locus_tag="L1V38_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316134.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(18809..19078)
                     /locus_tag="L1V38_001582"
     CDS             complement(18809..19078)
                     /locus_tag="L1V38_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316135.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19090..19839)
                     /locus_tag="L1V38_001583"
     CDS             complement(19090..19839)
                     /locus_tag="L1V38_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316136.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(19836..20528)
                     /locus_tag="L1V38_001584"
     CDS             complement(19836..20528)
                     /locus_tag="L1V38_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316137.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            complement(20534..21205)
                     /locus_tag="L1V38_001585"
     CDS             complement(20534..21205)
                     /locus_tag="L1V38_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1316138.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(21198..21539)
                     /locus_tag="L1V38_001586"
     CDS             complement(21198..21539)
                     /locus_tag="L1V38_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316139.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(21717..22415)
                     /locus_tag="L1V38_001587"
     CDS             complement(21717..22415)
                     /locus_tag="L1V38_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBN1316140.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            22502..22972
                     /locus_tag="L1V38_001588"
     CDS             22502..22972
                     /locus_tag="L1V38_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316141.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(23015..23194)
                     /locus_tag="L1V38_001589"
     CDS             complement(23015..23194)
                     /locus_tag="L1V38_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316142.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(23181..23519)
                     /locus_tag="L1V38_001590"
     CDS             complement(23181..23519)
                     /locus_tag="L1V38_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBN1316143.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(23535..23738)
                     /locus_tag="L1V38_001591"
     CDS             complement(23535..23738)
                     /locus_tag="L1V38_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316144.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(23753..24529)
                     /locus_tag="L1V38_001592"
     CDS             complement(23753..24529)
                     /locus_tag="L1V38_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBN1316145.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            24828..25148
                     /locus_tag="L1V38_001593"
     CDS             24828..25148
                     /locus_tag="L1V38_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316146.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            25166..25597
                     /locus_tag="L1V38_001594"
     CDS             25166..25597
                     /locus_tag="L1V38_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1316147.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
BASE COUNT         7247 a         5321 c         3993 g         9206 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 agtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta cgaacattta gtgaacagtg
    14821 taattttaga ataaagagag ttgttctttg tacttctcgc tattgtaaaa atcaatttcg
    14881 ttttcttttt tcaatcggtc agcttgtctg tgttcatact catctaaaaa gttcaatgtc
    14941 tttctaattt ctgcatgtcg ctgtctgaca tacgatgagc tatacccaac agattcagca
    15001 atatcttcta agctcatttg atcaacatat ttcatcttaa caatttgatt atcgatacca
    15061 gaaaagctat ctatcagcaa taacatttct tctttttgct cgatcaacaa ttccaattca
    15121 ttttctatct tttggatatt ctcttctaaa gaagaagttc tcgaattctt ttcgatgcgg
    15181 acgtttgcta aatcaccaca gacccatcga ttcaattcaa gcttactttt attaagattc
    15241 cactttaagt aaagaatctg ctcatctagt tcttggtaat cttttaacca atgaaatctc
    15301 acaaacgcca ccccttatgg tagaatagta ttgcgctgct atctcgaaag gggtagcttt
    15361 tttatttttt cttagccgtt ccattctgga ttgccttttg ttccaaacgt cgttttttct
    15421 tcttaatctt tgattttgtt tttcccatac aattctcctt tccgaaaaca cattttgttc
    15481 gatttttaat actaaataaa agttggccag aatttttcgt tcgtctttac tcatcttttt
    15541 ttgaataaga ttactagcat aaaaatagtt agtaccacga aaatgaacag gtaaatcaat
    15601 tacgttcacc ttcttcatgc cagttatcag ccactagaat ctttgcgtta gtgccgccac
    15661 cgttttcttt tttgtatttt tcaaatgctt tataagcagc tgtttttgat ttatagattt
    15721 ttccggaacc gactgggaac atccatgtgc cctctgtgat agctaagatg tatactttca
    15781 tttaattcac ccctttaatc cccaacacta catatccgga cttctgcatg taatcagtaa
    15841 tataagtgat ctctgctttg tatgagtcac cagtgtaact aaatgttggt ctcgttagtc
    15901 caggtaattc atgtttaatg tattttttat attcacgtag tattaactga tcaccaactt
    15961 tgaagtcacg atcattcttg cggatctcga attgtttgcg tccgctcgtc actgcttcaa
    16021 aatattctgg tagtattttt agttcgtgga tcattctgtt tcctccttca aaattcgctc
    16081 atcatcaaaa agtgaatctc cacaaaatcc ttctcccaaa tatttatcgt tcatgtataa
    16141 gtcaaccaaa tatttgtgat ctgcttctcg atattcatta atattaacga tctttatttt
    16201 gtaaacatta ccttcgtcgc tcactatctt gaattgttct ctgactttca ccaccgttcc
    16261 tcctcttttt gaaaaaattt tagtgttttt gtaagacccc ctaaatcagc ttttttattt
    16321 gatataatac ttgtatcgat taatcaaatc gaaattaaat ttaaaaaggt gatttatcat
    16381 gaatatcaac aatttagtaa aactcgttga acaacgtttt aaagaatcag gattagaaca
    16441 attaaaaaaa gataattctc cagaattatt ttctaatttt accgaagacg acattcctac
    16501 tcttaaacaa ttaaaatatt attctgatta ttggacgcaa actcgtgaga atgaattaaa
    16561 tttagaaaaa ctcattatta aaaagaaata gcaactccag cccacacggc tggtttttta
    16621 gtttcaactt ccctccttac gggtcaaaat catcggttcc ggcataatct gatcatcctt
    16681 tagcaacaaa tcaggatatt ttttccttag cttcttattg ttcgtgtaag ttttcaatag
    16741 ccattggttg gcttcgcttt tgctttctcc agaaaaataa attttccctg tttggatgcc
    16801 tgcaagttga atcatcattt tcacctcaaa tcaaattttt tctgctagat ggagcaaaag
    16861 caatccgaca tcaagaatct tttgacccat tatttcagct actttgctcg gcttaactcc
    16921 ttgagaaaag agcaagcgtg cttgctctat ctcttcgtga gtccaaataa atttggcttc
    16981 ctcaaggata attactggat cagttgctct cattgttcct ctggaaaaat gatgtcattc
    17041 ttatgcttgg accaggtatc tgcatatgga acaaagtatt gtctagctaa ttcgatttga
    17101 tcaattaaag cagtttctga taattcatgg tctgcagcaa tttcattcat actatcgcct
    17161 tcatctaaac agataagacc gttgacgtta tcgattttta catttgtgac tgcttgactt
    17221 tctccacgct cataatattc tacagttgat actgatacat cagcttcgga gtttaattgc
    17281 agaatctgtt actgccggga taatttaata ttcttttcat aattcacctt ttttcctact
    17341 gacatcgaat atttttcatg ttatgattag ccgtgaaagg agagctatat tatgtgttta
    17401 cacatgatgt ccttagctca ttcggttctt tggaagcttt tttggaaata actctcaggt
    17461 tcttgacgca aatctcattt attctttgaa acaaaaaact tccattttcc gagagctttg
    17521 gatcacttca aaagagattt gcatttatat ttctgtgacc ttgagtcgcg taaagaacct
    17581 tacagcaatg gcggcaattc cactttcagg aaaccgcctt ttttcattga tattggtggt
    17641 tagcggacta cccattttct ttcggcagtg ccaaaccaca aatgatctgt gttgatgttt
    17701 aggtagttgt ataccagata agctaaatcc aaagtgcctg catcttcaag acgacaatat
    17761 tccaaaaatt ctcccatagc tggacataaa aatcctggag ctatcatatc ccaacagtta
    17821 atagtgcaaa gaaattcgtt tagcttctga acgttttctt tggtttcacg aattacaaca
    17881 tactccaatt cttctccgct ggcagagcat tccaaaactt caaattgatt aagaaatggt
    17941 agaacatatg cttcaaacat caacattcca tctttctgtt tttgcacttg ttttgcatca
    18001 atcatgtcta tcctcctatt cagttatttc ttccattaat ggaattattt caggtcactg
    18061 gacttaacga aaacaccatt gaccatcttt ccagtccgac ctttgatttc gtcataagca
    18121 aaatccaagc actcgtataa atccatatca ttttgcattg ccaagatgat caaggttact
    18181 actacatcgc caattccgtc tcttaaacca tgttcatctt ttctagctag agaagcggca
    18241 acttccccga tttcttcgac cgtttttaac atttgcttgc tgaaatccgc ttgatccaat
    18301 cccttatctt ttgcccactg ctctactttc gcgattagtt cgtccattat ttctcctcca
    18361 catacctaaa ctgtcttcct tttgaatcaa tccataagct cctagctcta tcccaaataa
    18421 tatttttgct cagaccagta atttcagata actgtttagc ggtacccgtt actagaattc
    18481 gatcaccatg ccagattgca atctttctcg gcgttctccg tttgggcttt tcagtccaca
    18541 ttgatttacc gagcttttgg acttctgcaa ctattttttt atcttcctgc caatcttctg
    18601 aataagtcaa ttcgataatt cgctgcattg ccgctttctt atccatcccg acattctcct
    18661 ttcagtaatt tgagtacttg atcaagtgcg ctctcacgtc cgccatgaaa tgtgttgagc
    18721 cacttgtctt cgtacgacac actttgtctt aaagcttctt gatgcattaa ttcgatctgt
    18781 gctgtaaatg tctttaggtc catcttgttt acacctgctc aagttcatta agatgttttt
    18841 gcaagccttt aacacaatca atgaatagta atttggtata tgctaaattt cttaattgcg
    18901 ttccatcgat atagagtgcg aaatagtatc tgagtttact ccaactcgaa cgatcattct
    18961 taattccttc aattccagct tcttcgagtt gatcatatac gtctctcagg acgtctaatt
    19021 cctcgccctt tttataattc gctatttcat taattagttc tagataatcg atcttcattt
    19081 ttccacctct tagaatggtg cttttgattg tctattagct cgttctagcg cttttttctt
    19141 gagataggct tcttggtcga ttgcccattc aggaagcttc tctcgtcttc ctgtgcgctt
    19201 gtatccactg cttgcgttct taggttcact tttttctttc cttgcccaac ttcgaatagt
    19261 tgccaaatag tttttataag tcttaccaga tgattcacaa tactctgaca gtcgttcgat
    19321 tcgctcttgg taatcattag ggaattctgt tttgagtttc tccatctgct catctgacaa
    19381 aagaacattt ttatactctc cgtatttatg acggacgggc ttagccttcg attttttcga
    19441 aggcggtaac tctcttatat attcttttgt attattaaat gtattattaa tagatgtatt
    19501 attatctttg actttttcgt caataggggt attgcgtttt tcgtcaatag ggtattgatt
    19561 aattcgtagg tacctattga ttatttgatt ggtaccctct ttgtaaatga tttcccgatt
    19621 caagtatcca aacttaatca aatcacttac ccatcgcgat atggtctctt tattcacacc
    19681 atataaatct gcaaagtact cattgcctgc ccaacaaaag cctctttcat tacacaaggc
    19741 cgttatctct ccgtataaca acttagtatt tggtttaagt cttttgtcgt accttacgtt
    19801 ggctggtata atcgcataat aacttcgatg ttctgtcatt tttcccctcc aatatttaac
    19861 tttttgattg ttttctggtt taatttgatc cctttgattt gatatttatt tttgaaatta
    19921 atcacaccta ttttgtgctt ctctgtgtga tggattctgc agagtgctgc aaatgtgtac
    19981 tctgcatgat caacttcttt gcgctttcgt cttcctagcg ctttgtcaaa gtgatcgatg
    20041 tcagctcctg ttttgccaca gatgcagcag actctttttg tgatgcattt gtagaagtaa
    20101 tattcttgat tcgcaggtaa aatctcatag ccttctttga aaggaatatg atgttcaaag
    20161 atgaaatcta agatgatatt tgctaagaca ttggcatcac tcacagttgt attcgattcg
    20221 tctttcaggc ttattttgcg ccctgtgaca ccttcaaaac gaaagtagaa gaattccttc
    20281 cagaagtccg ttggcatgcc tgtatcgata aaaatatcgc ctatcagcgc atagatgaag
    20341 tttcgttgct gtacggtgaa acgtctagga tcaataaaac gaatttcaat gactcgatca
    20401 ccatcgtagc cgtcatacat cgtctttagt cgatcaatgt tcacttcctc attgatggtt
    20461 gcgcttatgt cttttccttt gaactttttc agaaccgctg aatatgaatc gattaatggt
    20521 ttaaacactc atatcacttc ttatctaatt cttttctctt agctgctatt gctcgctcca
    20581 tcaaggcaca ttgctcatag cttaactgtt caatagtttc aacgttatca gctaagagcc
    20641 ctaatttatc tgtctgctca ttaacatatt cgattaaggt tttggtcata tctttaccca
    20701 tctgctcatt gaaagcttct agaatcgtct ctagcatgtt taatttcttt gtatcgattc
    20761 taggtggtgt tggaatatct tccccttgaa atacatataa tcccagtccg tgtagagcca
    20821 atgctttcac aaagcatcgc ttcaatgagt tattgatttg cattgcattt ggtttaacaa
    20881 ctggttggtt tcgataatct aaaacaggaa ataattcggt ttccgtgtgt cctttaaccg
    20941 ttactgagac agatacataa gtcccagttt catccataag aaaaggttta tattcctcaa
    21001 caagaaagtc ttgatgagtt ccagaaacaa ccctgtagtg tttgtactca ttaatagtta
    21061 ccgttgcctg tggatcattc tttttcataa tctcccacgc gtgagcccaa gataaataat
    21121 caaaatttcc ttttttcttg agaattttat ttaacttacg actaaaaagt ttttcaaagt
    21181 tcgttgtccc tttgatttca ctcatcaaat tctgcctcca tttcagcaat gtatttctta
    21241 cctggtccgt aataagagat atcaatcaag ttatctctgt cgtactcttc tagcgcatca
    21301 atcaagccat cttcgatgac gtaaatatat tcaggtttat tcgaatgctt cgatagatgg
    21361 ataagataaa catgatccca aatagttaca tggttgccta aatcatcttg atcccaagct
    21421 agttcttcat tcgtcaaaag atttcgtctg atttttcgac cacttgtttc ctcaattttc
    21481 ggcttgcccc aatcaggatc aatcaaatat tgatctagag tggaaagttc tttttccata
    21541 tgctaaaatc tccttatgat gtgttttctt tgtgactctt tgcttgccgg cggagtcact
    21601 tttttatttg ttgccatgct ttttgcttgt caatatgttg ttggcttagg atgattggtt
    21661 tatagtattt ccaccagcaa ttagcaattg ccgtccctat tcttagcgct tcagctctat
    21721 tcattgtcat caccaaaaag tctctgttgt ctgttcagtt gatcaatttc catacggatc
    21781 gcagtttctg gcaaccacat ttcaataaat gaaacagcat catcgaatct cttacgaggt
    21841 aactcgccat atcttgggat tgaaaaggta cgtttaaatt cagaccaaaa ttttgagaat
    21901 acttttttgc tgatttcttc ataagctcgg ctttcttttc cccctagaac tcccataact
    21961 ttcatatttc ctttttgctt aatttcaaac tcttgttgtc cgctaattcg catagtatct
    22021 ttaagcatgg aaacatcttt tttaacatct ttcatttctt ctaattgata gatcatcata
    22081 tcttcaattg tttgaggaac agtattcttg cgaataacat cttccatttc gttgaatgct
    22141 tcaatgtatt tttgtttgaa gtagatagct ttctttcctg taaaccccat agccagcaag
    22201 aaaaatccat ctctactaat gaagaaaact cgtcgatttc tgccatatga atctggttca
    22261 ttaccttcta caaacatctg tccaaaattg gacacatctt tttttagtgc atcaatatct
    22321 cttaaaacat gttgatgttt tttctcgaag ctttctgcca cttgtaagct cgtagtcaca
    22381 gcttctttat ttttcaaaat tactaattct tgcattattt cttctctcct ttttggtata
    22441 atttagttaa aaactggtgg tgtttatttt gaattttttt cacttaacaa tttttcaatg
    22501 gatgtcaata ataagtttta tattgagtac gtttttaaca gggataaaaa taaaaggaat
    22561 gcgccctcaa ctagaagttg aacttaatgc ttcttacttc gctgcagata tgatttatac
    22621 aaaagtaatc atttctaact attcaacaga accagctatg ttagttaatt tagaactttc
    22681 atccgctaac ttaaaccgca gatggtcagc tactccattt aagaaattaa ttgctaaagg
    22741 aggatcagtc gatgataata gaatatactc tgaagctgta ccgctaaata ttcctcctaa
    22801 aagtgctata tcttgttacc ttgcatttga agtagggaaa attaatttta ataaactcct
    22861 taatcaccaa acaaaaatga tatttactct aaatagaacc caaatccaca aaattgttga
    22921 tatcaaaaat acaaacttcc caatagagaa attagtgaaa gaattaaact gagtaatagt
    22981 aatatacatt ctagtttctc ttttctattc atttttagtc agccccctcg gttggctttt
    23041 tcgctctgta ctcagcttca gcttcatcaa gccccataaa aatccaaacc atgtaaacaa
    23101 tcgttcctat caacgcttgc ctgcttcccc aaagtcctaa agcgtagatg attagcggtg
    23161 cgctgaacac tagcgctcta ttaaattttc ccatccgctt gcctccttaa gatttccgaa
    23221 aaatttgttt ctaaaaattc aagtgtttta cttcttaaaa atagatatgt gtctcttcct
    23281 tcaactggat aatagacaaa tccatttttg tttttctcga tatcgataat atttctatat
    23341 cttgggttct ttaaaactct agaagtaaac caatcatatt ttctgttaat ccgttctagc
    23401 acttctggca acgtcatcca tctaccagta tcatcagctt tttttaactc ctcataatcc
    23461 acttgggaga taattacata gccttctgga attgggattt ttgcttctag atattgcatt
    23521 agctgttcct ccctttacaa ttcgtacata gtgataatcg aatctataat tctgtttgct
    23581 tctgcagaag tctttttacc gtttaaaatt aaagataagt agcttttgct aattccaaat
    23641 ctttcagcaa gcatggtgta agttaagaac tttgaacttt cgacatattc tttgattttt
    23701 tctctatctc gttgagtgat ttctgcaatg tcagtcatac taaaactcct ttctaaccaa
    23761 tttcctctaa atccatttga gggtaatatc cttctttttt tagtaattcg tagataaata
    23821 gacgcccttt ctgtgtccat ttggtattca ttacaatttt agtgccacca tcggctttcg
    23881 ggatctcagt tgtatgagat tttgtgtatc cttggttcat gtgttttttg cacaataacc
    23941 attggttacc gacttttttc tgaataccta gtttatgaag taatttattc atctgttgtg
    24001 gagacatccc ataatctgct gcaatctgac taattgttac tgaatctgta gaagataata
    24061 tgctatctaa ataggagatt ttaggttcgt actctgcaat cttttgttct gcgattaatc
    24121 ttccagttct ttcttctttt agttgagttg ctaattgaat gattgtatct ggattaagca
    24181 aagcttcttc tactttttct ggagttagat aacctccatg ttttctaatt gctggcaaca
    24241 cttcacttgt tacccaacgt ttaaattttt tggcagaggg aagttttgat tttaagatta
    24301 aactgtacaa accagattcg ttgatgattg tcatctctct tgattgacct gaggtcgtga
    24361 ttcgcgaccc catcttatct tccaaatcta catgccgcga caaagcatct ttagtgtttg
    24421 aataacccaa aacactcgca acgtctttgc ctacaaaata tggttcatca tttactaaaa
    24481 ttgtccgaac ttcgttttgt tcgaaattaa aaatttgcgg tgtgttcata tttctcattc
    24541 ctttctttta tattcgtaaa caaatttaac aacttttttc taaattcaat tgacagtatc
    24601 tgagtaatac tctatactaa gagcataatt aaataagaca taaaaacatt gattttaaag
    24661 ctttcttggc ggtctgcatt tacatatcaa tagtgttttt tgttgtcttt ttagttgtta
    24721 aatctgttta caagatatag tatagctcat tactcagaat tagtcaaatt atttctgcgt
    24781 atttttctaa actttttttg taaacattta gaaaggttgt tttatcgatg aatacctatg
    24841 aaataataaa agacttggcg aagaggaaaa agatatctat acggcagtta gaaattaatt
    24901 ttggatattc taacggttat ctagcaaagt ggaaaaataa tactcctaat tcagatgaat
    24961 taagtcggat tgctgactat ttcgatgtct ctgtagacta ccttctaggt agagaagaaa
    25021 gagaaacccc taaacatgtg gatttatcag aagacgatac tgttttttct tttgatggaa
    25081 aagaaatatc taaggagaca atgcgtaaag cgattgcaat tgctaaagct ttagaggaaa
    25141 atgaatagtt ggagtgatgg tttgtatgta tttgaaattg aaagaaatgt tgagcgaata
    25201 caatttgaaa gtagtttata tggagatgaa agagcctggt ttctactatc caaaacccag
    25261 aatcattttt ttgaatgaaa atctatacgg tgaaactgca gaagcctttc atttatctca
    25321 tgaacttgca catttcagcg cctctcattt tgaattttca gttttgtacg atacttctac
    25381 aacttttcac tcaaaatttg aaacagaagc agataaaata gctattctaa ttttattaaa
    25441 tatctatatt gagaacgaac tgactgatga atctcagttt aatctcgaaa aatttatgga
    25501 gtattattct attcagaata agctcagata cacttgttat gctgtctgcc aatgctattt
    25561 taagaaaaaa tattcttacg caaggcaata tgtatgaata catcaagaat tattaaaaaa
    25621 accgatttca gcaaaacatt aaaaaagccc gtgctgcaac acgggctctt tcctcatata
    25681 tgagcttcta caaaaaaaat catatcacag aaatgaggaa gaaaaaatgg aaaaagagat
    25741 tttaataaaa tctccaggaa aaacctt
//
LOCUS       DAFLWZ010000036        25539 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000036 DAFLWZ010000000
VERSION     DAFLWZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.036"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            138..2198
                     /locus_tag="L1V38_001595"
     CDS             138..2198
                     /locus_tag="L1V38_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBN1316148.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2281..2850
                     /locus_tag="L1V38_001596"
     CDS             2281..2850
                     /locus_tag="L1V38_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1316149.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3025..3831)
                     /locus_tag="L1V38_001597"
     CDS             complement(3025..3831)
                     /locus_tag="L1V38_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316150.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3969..5483
                     /locus_tag="L1V38_001598"
     CDS             3969..5483
                     /locus_tag="L1V38_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBN1316151.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5886..6869)
                     /locus_tag="L1V38_001599"
     CDS             complement(5886..6869)
                     /locus_tag="L1V38_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBN1316152.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6874..7521)
                     /locus_tag="L1V38_001600"
     CDS             complement(6874..7521)
                     /locus_tag="L1V38_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1316153.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7606..8238)
                     /locus_tag="L1V38_001601"
     CDS             complement(7606..8238)
                     /locus_tag="L1V38_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1316154.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8254..8805)
                     /gene="coaC"
                     /locus_tag="L1V38_001602"
     CDS             complement(8254..8805)
                     /gene="coaC"
                     /locus_tag="L1V38_001602"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBN1316155.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8802..9539)
                     /locus_tag="L1V38_001603"
     CDS             complement(8802..9539)
                     /locus_tag="L1V38_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBN1316156.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9536..10525)
                     /locus_tag="L1V38_001604"
     CDS             complement(9536..10525)
                     /locus_tag="L1V38_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1316157.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10783..11325
                     /locus_tag="L1V38_001605"
     CDS             10783..11325
                     /locus_tag="L1V38_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316158.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11342..12427
                     /locus_tag="L1V38_001606"
     CDS             11342..12427
                     /locus_tag="L1V38_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316159.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12439..13245
                     /locus_tag="L1V38_001607"
     CDS             12439..13245
                     /locus_tag="L1V38_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316160.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13246..14073
                     /locus_tag="L1V38_001608"
     CDS             13246..14073
                     /locus_tag="L1V38_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316161.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14070..15143
                     /locus_tag="L1V38_001609"
     CDS             14070..15143
                     /locus_tag="L1V38_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1316162.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15571..18267
                     /locus_tag="L1V38_001610"
     CDS             15571..18267
                     /locus_tag="L1V38_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1316163.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18344..18832
                     /locus_tag="L1V38_001611"
     CDS             18344..18832
                     /locus_tag="L1V38_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1316164.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18844..19338
                     /locus_tag="L1V38_001612"
     CDS             18844..19338
                     /locus_tag="L1V38_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316165.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19359..20168
                     /locus_tag="L1V38_001613"
     CDS             19359..20168
                     /locus_tag="L1V38_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1316166.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20165..20986
                     /locus_tag="L1V38_001614"
     CDS             20165..20986
                     /locus_tag="L1V38_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1316167.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21037..23136
                     /locus_tag="L1V38_001615"
     CDS             21037..23136
                     /locus_tag="L1V38_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBN1316168.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23133..24251
                     /locus_tag="L1V38_001616"
     CDS             23133..24251
                     /locus_tag="L1V38_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1316169.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24290..25168
                     /locus_tag="L1V38_001617"
     CDS             24290..25168
                     /locus_tag="L1V38_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1316170.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25359..25511
                     /locus_tag="L1V38_001618"
     CDS             25359..25511
                     /locus_tag="L1V38_001618"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1316171.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8067 a         4449 c         5408 g         7615 t
ORIGIN      
        1 ttttcttgaa acaataaaaa atcaaaaaaa atactctcct aatagtccat cttcttttga
       61 ttttatttat ataatgaaat catcttatga aaattactac ttcatgttta gacaagagta
      121 gggaggacta agaataaatg tgttcaaaaa gacgttcaaa acaactaaat aaacacgctt
      181 gtcgtttaga taaggaacgg tcgtgttctg aaaaacacta cgttaagttt atgatgcgca
      241 cgatgctgat cagtttatct gtaggtgtct atatgcatgt acccgttcag gcaacgacac
      301 aaaccatcaa ggtcgtacgt acctctgttt ctgagaccac tgattcccct atcactatta
      361 ctcatacttt cactgatgca aatggaaaac agctacttcc tgcattgact tcctataata
      421 aagtcagtta tcctccaacg ataaaccact actggttaat tcctaacaaa acattatgga
      481 catcggaaac cggaagcagt gtgccgcttt ctatcttttc cgatatgact gatcctacaa
      541 aaggtgatca gttaaaacag atcactgata ttttgaatca tgctttgaca gatataaagg
      601 acggtggaag cgcacaagtt tcttatgtat atgaaaaaga ttattcacag tttgaaagaa
      661 agaaaatcga tgttctggca gggacaaaag tttcgatatc tgatctggta gaaaggctga
      721 agaacgcaga tggaacacaa ggagatatgt ccaaagtaat ttcaaacaat gggaatatcg
      781 tggatacgac taatacagga acatctacta tttccttgtc ctattttgat ccaattgctt
      841 taaaaacaat gactgcatct gctgtgatcc atgttcgtgc tgatcaaaca gctatcaaag
      901 gaaaagatct tcacttaaga acaggagaga gttacgcccc taaagatctt gttgaatatg
      961 taacaaaaag cgatggaact tcaggaaata aagaagaaat caaaatgaac gggacagtag
     1021 atactacaac tccgggagaa tatcccgttg tattaactta tatagactcg aaaacatcaa
     1081 atgtggcaga aacaacagct gtagtttatg tagaagcatc tgctgcttca tcgactgtca
     1141 tcactcattt tatagatagt caaacaaata aagaacttca agcagaaaca catatgagta
     1201 gtgtaaatcg tattcctgat ttgcgcctac ctgctgaatt ttctgatcga gtgccaaata
     1261 tagatttatc gacttatgaa caaaatggga aagtcacttc tatttctgat tggatgcaag
     1321 caaacggatt agacagaaaa agtcactggt cggagatcct tgaagtactt cactcagaac
     1381 tgatgaataa taggaagcaa tcaggagggg aaattacctt tacttatgtt tatataccag
     1441 acaatcgttc attagaaggt catgatctta ttgttcatcc aaacgaaaaa ataaacaaag
     1501 aagagttgat ccaatcagca acaaattcct taggtaaacc cgtaccgtta aaggatgtat
     1561 cggttacaat caatgaagta ccattggagg atggttattt gaccaaacaa acaggtgatt
     1621 ttacgattat gtatagttat catgacccgt attcactcca agaactccat gctcagtcac
     1681 tattacatgt tttaccatta aacaaacaga tagatcaaaa agaacaaaaa agacaagaag
     1741 aaagcttgtc agaaaaaaaa caacaaatgg ctcatgcagt ttctccaaca gggaaagtaa
     1801 aacaaacaag aagcctagag ttagcaagaa tatctagaaa aatctcagaa tctaataaaa
     1861 cgataaggca agaagctcat ttggccccac aagtttctgg attggaaaat gaaattttag
     1921 agcctaaaat aaaacaacaa tcagaaaaag aatttgttgc taaacagtcg gaagatcaga
     1981 aggaatcaga tgaccagaag gaaacgaaga aaaaacgctt gtcaactatt gattccaccg
     2041 atgagcatct gcagccgcaa gtaccacttc ctagtccggg aacacccgca cctggtggag
     2101 gtattccttc ttctgcttta ggagatttca tgcgaggtat ggcaggaaca tgggtatacg
     2161 ctaatcgaaa tgaatttgac gcagatgact ggttctgatt tatatctcta tctgttatag
     2221 tcaaataagt agctgagtca tatgttattt ggcataatgg agacgaggag ggatagaaaa
     2281 atgttagata aaacgttacc ttacgcagaa atctggatga caagaccact tcaacaaaat
     2341 gttccaatca cgcctttagc ggaaggtttt gaatttcgat tttatcaaaa agaagatgaa
     2401 tctgcttggg cggagattga gacttccgtt ggggaatttc aaacgacaga tgaagcactt
     2461 gagtattttc aacaaaactt tgctccttat cctgaagaac ttgaaagaag gatgtttttt
     2521 gtagagacaa aaaaaggaga aaaagtagca acctgtaccg cttggcgaaa aaaatcaaga
     2581 gagcaagtgt atccggtttt tcattggtta gcagtgaaat cagattacca aggaaaaggg
     2641 ctcgcaaaag cattgactgc cagagtcttg caagaatttc ctaccctcca tacggacgga
     2701 ccaatctatc ttcacacaca gacatggagc catcaggcga ttgctcttta taaaaaaatg
     2761 ggttttactt ttattgctga aaatctagac ggcacaccta atccagatta tgaaaaagtt
     2821 atgcaggttt taagtaaatt agataaataa cgaaatggtg aaataagtcc tcagtattgg
     2881 gataaaaaac gaaatagtca ttcctcatat cttacttttt tgagttaata ctatcggata
     2941 actaatggca tgccatacat tcaaaaaaga aggggcagtg acaaaagtat tgtcactgcc
     3001 ccttctcttg ttttttagca tgttttatcg tttgattttt ttaggaataa aattcttgat
     3061 gaacgtaaat ttttggtaat cgtttcgact atagaggtaa ccaaatacac tgaaaacaac
     3121 tgctccaata aaattaacaa ataaatcctt catagtatcc atgattccca cgtctaagta
     3181 accattttgg atgattgttt tatctgtttt accatctgca ttttgacttt caatgattgt
     3241 ccgagtgata tctggaacat gatagacagt gtttccgtct ttacttaact ccacactatt
     3301 gatttgctgg atgatcgtat ctttttgcat atcgaattgc agtaatttat ctgctgaaaa
     3361 ttccacaaac tcccacataa caccaactgt catcgaaaaa cagaaggaaa caactgctag
     3421 taataaagga gtcaagttca tggtttttgt atttttattg agcaaataaa caagggaaaa
     3481 gccgacaccc ccagctaaaa atccgctgaa tgcatgtaga aaagtatccc acattgaaaa
     3541 atagccataa aaatcactta actctcctaa aactgttgaa ctaaaaataa aagataacaa
     3601 aatgatttct agcatatttg gaatctgtat ctttaatatc ttttccagaa aataagggat
     3661 ttcaaataaa attaatgtca gtaataaaag cattgtattt ccccagtgtt ggttccagac
     3721 ctgatccact agcataataa cgacgatgat acgtaataaa atatagattc cgtttgtgat
     3781 tctacctgca gtttttgtac tgttcgtaaa aaaggttttc aaatgattca taaaataact
     3841 ccttcatgta tatccttaat tatactaaga agcgtgtgtt taccaaagct atatgactta
     3901 aagaaaaaca gagttgatat tgtgaaaaaa atcacttaat atagtataag gagaaaaggg
     3961 ggatacaaat gaaaaaatta gttgctggtt tattaacagc cgttgcactt cttgctatga
     4021 gcgcatgcgg cgcagatcag aaaaatacag cgcagacaag ttctagtacg aaggaatctg
     4081 ccgaagtatc atcaggcgct tctgaacaag tatatacaga tccaaaagaa atgaaagaat
     4141 cttatgatgt cgtgattatt ggagctggtg gtgcagggat ggcagcagct atcgaagcaa
     4201 aagatgctgg gttgaatcca gtaattttgg aaaagatgcc tgttgccgga ggaaacacat
     4261 ctaaatcatc aagcggtatg aatgcttcag aaacaaaatt tcaaaaagaa gaaggaatca
     4321 aagactcgaa tgatgccttc tatgaagaaa cgctaaaagg tggtggagga acgaatgata
     4381 aagaaatgct tcgatacttt gtcgatcact ctgctgatgc ggtcgattgg ctagatcaaa
     4441 acggtatcaa actggacaac ttaacgatca ctggagggat gagtgaaaag aggacacatc
     4501 gtccgtctga tggctcggct attggtggat acttagtgga ggggttattg aataacgtcc
     4561 atgagcggga aatccctatt tttgtcaacg cagatgtgac agacattaag aaaaatgggg
     4621 aaacggtcaa tgaagtgact gtacatgttc aaggagaaga accaaaagag gtcaccggaa
     4681 aagcaatcgt agttaccaca ggcggttttg gtgccagcaa agaatttatt gaaaaatatc
     4741 gtcccgattt agctgattat attacgacaa atcaagaagg atcaactgga gatggtatca
     4801 ccatgattga aaaattaggt ggacaaaccg ttgatatgga taaaatacaa attcatccaa
     4861 ctgtgcagca ggatgagggg gtcttgattg gtgaggttgt tcgcggagaa ggagcaatct
     4921 tggtcgatca agaggggaaa agatttgtca atgaaatgga tacaagggat aaagtatctg
     4981 cagcaattac agcattgcct gaaaaatcag cttatttgat ttttgaccaa ggcgtgcgtg
     5041 atcgtgccac agctattgaa ttttatgacc aaaaaggata tgtcacaact ggaaagacaa
     5101 tggaagaatt agcagaaaaa atcgatttac caaaagaaac actagcaaaa acagttgatg
     5161 gatggaatac ggatgttgcg gagaaaaaag atgctcaatt caaccgtgcc acagccatgg
     5221 aacatgactt atcgtctccg aattattatg cgatcaaaat cgcaccagga atccattaca
     5281 cgatgggcgg tgtgaaaatc aatacgaaca ctgaagtatt agataaagaa aaccagccaa
     5341 ttagggggtt atatgctgct ggtgaagtca caggtggctt acatggaaac aaccggatcg
     5401 gtggaaattc agttgcggag atcattattt ttgggcgaca agcgggcata caagcagctc
     5461 gatttgcttc ggaaaatgaa tgaaatagaa cgtaaataaa aagaggttgt gaaatcagcg
     5521 ttttgagcta ataccgaggg tcagctgatt gaacactgtt tagtgaagag gttgtgaaaa
     5581 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac
     5641 ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg gaaaaagagc
     5701 gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
     5761 cagaagaaat tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt
     5821 gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt ttgatcagca
     5881 tgattttatt cagttatctt caaaatgatt tttccgatgt ttttgtttgc ttccatatat
     5941 tcatgcgctt gtttgactgc gctgaattgg aatgtacggt caatgattgg ccgaatcttg
     6001 ccattttcta gaaaaggccc agctttttgc ataaaagttt gtgcgagctc tgctttatac
     6061 tgatcacttc taggtgtcaa taatgtacca agcagttgga cacgtttccc aatcaataca
     6121 ccaaggtcta tctcaggcac gatggtccca cctagcatac caatcaagac ccaacgtcca
     6181 tcaacggcta tagaagctaa attcttttcc cagtaagaag cgccgatgaa atccaaaata
     6241 acatcgactc cccgaccttc agtgattttt cgtacctctt cttgaaagtc ttgtttttta
     6301 tagttgatca attcatctgc accaagttct ttacaaaagg cgagtttttc ttctgatcct
     6361 gcagtaacga tgattttcgc gtgagaaagc tgtctagcta attggatcgc tgctgttccc
     6421 acaccacttg ctcctgcatg gatcaagaca gtttcgcctt cttgtaattt tccaagccag
     6481 taaagtgttt gataagcagt caaaaaaact tctgagattc cagcagcaga aacatagtct
     6541 agcgtatcag ggagaaggat tgcacgatcg gcaggcatca cagcatattc ggcataacca
     6601 cctagattga ctaatccgta tacttttgtc ccaggagtaa aagtggagat atcactttta
     6661 ttctcaacta cctctccagc tacttcgact cccaaaatag ggtagggagg tttcaaagag
     6721 actgattctc ttttcataat atctgttcga ttgacagctg ctgtatggac tttgatcagt
     6781 aattcgcctt gttttggttt aggaacaggc acttcaattt gttctaatac atctacagaa
     6841 ccaggatgct tgattgaaat ggcacgcatg gatctattcc tcctttgccc attcttggaa
     6901 tgctgtattc aactctttgc taccttcaga aagtactaga gtcgtacgag aaatatccgt
     6961 ttcttccact agagcggcaa gtacagcagc aactgtagag cgagtgatcg tttttgatgc
     7021 cttctcatta ggcttagtta attgaatgga agtaacttct tcatcgttag tcaatgtgac
     7081 tggttgaaga atgacaaaat ctaagttagt tcgtttcagc cattcatctg cataatgttt
     7141 agtaatataa taatctgtca tggactcagg ccattttgct ggttcatctg cataaacagc
     7201 actgaccatc agatagcgag agacatgcgc attttcagct gcgatcactg ttttgattgc
     7261 gccatccaag tctacttgca gaagattctt tccttgagag ccggcagcaa aaatcaatac
     7321 atcgatgcct ttgaatgctt cggtcatttt ttccacggac caagttaaat caaaagagac
     7381 atacgaaaca ttctcttttt ttactaatgt ttgggaagca acatctctca cccctgcaaa
     7441 aatttcatgg gaacttggag ctaaatcttt tatcaggtgt cggccaattt gtccgtttgc
     7501 acctacaaca aaaattttca tttggatcat cctttcgacg tcaaatcttt ccattcaata
     7561 gtaacaccaa aagagaaaaa aatcagagat cggctacgat gactatcagt tagtaagaga
     7621 agggtgcttg aagtatctta acaagacatt gcatactgct gcagtcgcaa gacctgcgac
     7681 gattccttca ggtataccac ttgtaaaaat aaccgctaga atagctgaat aaacagcatt
     7741 taaatttgtt ccgatgactt tggcataatc ttgctggaat aaaaagtaga tcatattcat
     7801 cactaaaatc gtattggtca atgaaccgga aagtccagct aagaataaag aaacggaatc
     7861 tgctttttgt ttcattagtt tgcgcagacc tttataaacg aaataaggaa ccaccccaat
     7921 caagatgcga ggaataaacg cgatcagcaa ggctttccag cttccatgtt ctgttccgat
     7981 gactgggata aacggagaaa agacaaaaga caaaggtgtt tggataactg tgctacggat
     8041 catgctgatc agtccaaatg taccgccaag aaaagcacct agtcttggtc ctaaaacgat
     8101 cgaagcaatg attacaggaa tatgcatggt tgttgcattg attggaccga tagggataaa
     8161 acctaaaggc gtaacagcta ataaaatcaa aatagctaaa aacatcgcag ttaatgtaaa
     8221 gttttttgta tttttcataa gtactccttt tttctaagca tttctttcat taagagtcag
     8281 catgacctgt tcgatgatcg tctgaatatc agctaaggca ccttttccaa aatctccaca
     8341 agctaaaaga gattctcttg gttcaatttc ctgatagccg acagatctca atgtttccag
     8401 attacgctga gtgatcgggt tttgatacat attcgtgttc atggcagggg caatcaattt
     8461 tggtgttccc actggaagcg ccattgcgac tgttgaaaga agatcgtctg caatgccgtt
     8521 tgctagcttg ccgataatgt ttgctgtagc aggcgcgatg agaaacaagt cagcttgttt
     8581 tgctagttcg atatgattga ttacctgcgg atttgattct tgcatgacgt ctgtatggac
     8641 tgcgcgcttc gacagagatt gcaaggttaa tggcgtgata aaatgtgtgc tgcttttaga
     8701 cataatcaca tctacctggg cacctaattt gacgaattga cttgtaagat cagcgctttt
     8761 gtaagcagaa atacttccag taacgcctag taagatcttt ttcattttga ttcctccagt
     8821 ctaattttct cagtaatcaa tgcagcaatc tcagatttac tttgagcttc ttccactgtt
     8881 ccatctttag ataagagata gccgtggtgt gtctcgccat ggatttccgt caaatcattt
     8941 gcgaaaataa aatcagtttt gttatttatc agactatttt ttgcgactgc cagaagagat
     9001 tcctttggta catctactaa tagtttgaaa ccaatgattt ttgcttttgg ctgccattca
     9061 cgtagataag aaatgatttt tggtgttttc ttcaaaacga gcacaagatg ctcggtgtta
     9121 gaagagatct ttgaaacagt ggtatctgtc tgttcatttt ccgcaaacca attgtccagt
     9181 tcttcttgcg ttgaagaagt gggtaggttt tttgccagct gttcttctga aaaactaaaa
     9241 gcaggagtaa aatcactgac tgccatactg tggataatcg catcgtagtg ttcttttttc
     9301 gttagttctt ctaattgtaa aaataagtcc agtgcagatt cgatcgtata aatcgttata
     9361 ttggagtgtc ttttcggttt cagtgcttgt ttcgtagtca cgtaatcgat tgtggtatcc
     9421 ggattggcag ctaaataatc agctaatgct tgccctaatc gtcctgtcga atgatttgta
     9481 atagcacgta cttgatcgat tttttcagtc gttcctccag ctgtgattag aatcttcatt
     9541 tatggtcacc tacatttact agtgttcttc cttggtgtgt tccagcaagt agtttagatg
     9601 ctgtttcagg caattgatcc agagtaatct cttggacgac cagttcatct gcaatctgca
     9661 aatccgccat ctgttgccat aaagaaagac gttgatctat tggtacattg acagaatcaa
     9721 ttccaatcaa ctggatgttt cgcagaataa aaggcaagac agtcgcgttt agtttgattc
     9781 ccccagcatt gccacataaa gctactgcac cgttataaga gatcaatgga agaagactgc
     9841 ttagctgctc gccacctact gtgtcgatga catagtcgat ttgctgtttt cctaaagctt
     9901 ttgttgtctc tggcagaaat tcatcaggtc gtacgacttg caaagcacct agacttttta
     9961 gccatgtgac agactcttct tttctggaaa aggcaatgat tgactggaat cctagtttat
    10021 gtaacagggc tatcgctgta ctgcctacac cgccagaagc accagtaacg acaacttttt
    10081 tatcggaggt cataccttga cggattaaag cgttcacaca caacatagca gtaaaccctg
    10141 ctgtaccaag gatcatcgct tgacgcagcg tcatattttt tggtagagga actaaccagt
    10201 ctcctggtac tttttgatat tggctataac cgcctggatg ggtgacgcca agcccaaaac
    10261 cagtagcaag tacaagatct tcttttgaaa aacgtggatt gttactttgg acgacagttc
    10321 cggataaatc aatccctgga gtcatcggat atgttcgtat cacctgacca gactcgctca
    10381 ttgccaatgc atctttataa ttgacatcag aataggcaat ttttaccaag acttcatttt
    10441 cagccaactc agtaaatggc agatcactga ttgctgtatg gaaaacaggt tcctttatta
    10501 cctgaaaaga tcgaaaagcg ttcattcgtg agacactcct tttaaaattt tcttttatca
    10561 taccataaag cctactcttt tattcttgtt cttccgtaaa tttagacaaa aattaggtga
    10621 aaaataaaga atcaaacaac tagaatttat tccaaaagat aaagaaatat tcagcaaaaa
    10681 aaattttaca aagggttgcc tttttcaata aatttcgtat actaatacga gtggtagtaa
    10741 acaggaagtt tactattaga aaacttcgat tcggaggaaa ttatggaaat tggtgagaag
    10801 ttaagaaatt tgcgcatcca aaagaatttg acacaagaag aactaggcga acgcacagat
    10861 ttgtcaaaag ggtatatttc ccagttggaa cgagatttaa gttcaccatc aatggaaaca
    10921 ttcttttcta ttcttgaagt cttaggtgtg actccagaag aattttttca tcaagaagca
    10981 gcgaatctgc aagtggttta ttcaaaagaa gatcatacgg tttatttcga tgaagaaaac
    11041 gggtatgaat tggaatggct cgtggctgat tcgaatgaaa aagaaatgga gcctgtcttg
    11101 ctgacttttg aaggtgcagg agaatataag acgtttgaac cttcattatc tgaaacgttt
    11161 atttttgtat tagaagggga attagagtta agcttaggag agacggtcta tgtggcaaaa
    11221 gcaggacagt cgatctatta tcaagcgaca aaacaacatc aattaaggaa tcatctcaaa
    11281 aaacgaacaa aagtattgat tgttgcaacg caatcatatt tgtaatatag ggggtaaaaa
    11341 cgtggggaaa ccaatcattt catttgatca agtagtgaaa cgctatgatg atgaaacagt
    11401 attaaaaaaa gtaagttttg agatcgaaca aggaaaattt tatacactgc ttggtccttc
    11461 cggctgtggt aaaacaacga tcctacgtat tatagctgga ttcaccgaag ctacagaagg
    11521 ggacatctat tttgaaggga aacggttgaa tgatttgcca gctaataagc gacaagtaaa
    11581 tacagtcttc caagattatg cactttttcc tcatatgaat gtttttgata acgttgcttt
    11641 tggattgaag atcaagaaaa tgtccaaatc agatatcgaa aagaaggtaa aagatgcttt
    11701 gcgtatggtc cagcttcctg gatacgaaaa acgggagatt agtgaaatgt ctggtggtca
    11761 aagacagcgt gtagcgattg cacgagcaat tgtaaatgaa ccgaaagtat tgctattaga
    11821 tgaaccgtta tcggcgcttg atttgaaact acgtacagat atgcagtatg aactgcggga
    11881 tctgcaacaa cgattaggaa tcacgtttat ttttgttact catgaccaag aagaagcgtt
    11941 ggcaatgagt gatgagattt ttgtcatgaa taaagggaaa atcgtccaaa gtggtacacc
    12001 cgtagatatt tatgatgagc caatcaatca tttcgttgct gattttgttg gggagagcaa
    12061 tatcgtggac ggtgtaatga tcgaagataa tctagttgag tttgttggta agcaatttga
    12121 atgtgtcgat ggcgggatgc gtctaaatga accagttgaa gttgttttac gcccagagga
    12181 tttgacgatc acgacaccag ataaaggaaa actagtcgta acggtcgata ctcagctgtt
    12241 tcgtggtgtc cattatgaaa tcatctgtta tgatgaacag caaaatgaat ggatggtcca
    12301 ttcaacgaaa aaagctaaag aaggaagcaa agtaggattg gcctttgagc cagaagatat
    12361 ccatgtcatg cgtttcaacg agtctgaaga agaattcgat gcacgtcttg acagctacga
    12421 agaatagggg ggacaagaat gaaaacaatg cgcaggatct attccgtccc ttatattttg
    12481 tggctcggtt tattcgtgat cgcgcctgta ttaatgatca tttatcaatc tttttttgat
    12541 atgaatgggc aattcacgct gaataattat ctatcttatt ttacgtcggg gacatcgctt
    12601 tctatgacga tcaattctgt atggtatgca tttttgatca cgtttttcac gctgatcatc
    12661 agttacccga ctgcttattt tttaacaaaa ctgaagcaca agcaattatg gctgatgctg
    12721 attattttgc ctacatgggt gaatctgctg cttaaagctt acgcatttat tgggattttc
    12781 agtgtgcacg gcagcgtgaa tcatttcttt gattttatcg ggatcgggcc gaaacagata
    12841 ttattcacag acttcagttt tctgttcgtg gcaacgtata tcgagattcc atttatgatt
    12901 atgccaattt tcaatgcatt ggaagagatg aatccttctt tgatcagtgc tagtagagat
    12961 ttaggcgcga atagctttga gaccttccga cgagtgattt ttccgttatc attaaatggt
    13021 gtgaaaagtg gtgtccaagc agtatttatt ccttctcttt ctttattcat gctgactcgt
    13081 ctgattggcg gaaatcgggt gatcacttta ggaacggcta tcgaacagca tttcttggtt
    13141 acacaaaact gggggatggg ttctacaatc ggtgtgattt taatcattgc tatgttcatc
    13201 gtgatgctcc tgacaggcga gaagaaaaaa ggaggtcgct cataaatgaa aaaatttaaa
    13261 tggtcgtatc tttatttagg gatcgtcttt ttattcctat atgcaccgat cttctatctg
    13321 attttttatt ccttcaatga aggaggaacg atgaacagct ttacaggatt tacttgggaa
    13381 aattatgaag ctgtttttga agatacacgt ttgatcatta tcgtattgaa tacgttcatg
    13441 ctggctttct tatctgcatt gatcgccacg atcatcggga catttggggc tatgggaatc
    13501 tattacacga aaaaacgacg tgcacggaca gcgttgttga gcatgaataa catcttatta
    13561 gtctctcctg atgttattat cggtgctagt ttcttgattt tctttacact actaggattc
    13621 ggattaggtt ttcagagtgt attgctttcc catattgctt tcagcattcc aatcgtcgtc
    13681 ttgatggtct tgccaaaatt gcaggaaatg aacgattcaa tggtcgatgc ggctagagac
    13741 cttggtgcta ataatttcca agtagtcaaa aatatcattt tgccttatct ttctccagga
    13801 atcatagctg gatattttat ggcatttacc tattctcttg atgattttgc ggttacattt
    13861 ttcgtcacag gaaatggctt tacgacgctc tcagtagaga tctattctcg tgcaagacaa
    13921 ggaatcagtt tagaaatcaa tgcgctaagt gcgttagttt tcttgttctc catgatattg
    13981 gtcattggat actactttat tagtaaagaa aaccgtccaa aacggctgaa gaaaaacaga
    14041 agagtacgcg agggggtggc acggctgcga tgaaaaaatt acaatctctg tttttaggta
    14101 ttctcatcat tattgcggtg ctgctgcttg gtgttcgtca acttgaaaaa acaagtggca
    14161 tgagtggagc aaaggtactt accatctata actggggaga ttatatcgat cctagtttga
    14221 tcacgaaatt tgaaaaagaa tatggataca aagtgaatta tgaaacattt gattctaatg
    14281 aagcgatgtt cacaaaaatc cagcaaggtg ggacaaacta cgacatcgct ataccaagtg
    14341 aatatatgat ccaaaaaatg atcaaagaaa aactagtact tccattagat cattcgaaga
    14401 tcaaaggatt aaataatatt gatccacgat ttttagactt ggattttgat ccagataatc
    14461 agtattcgat tccatatttt tggggaactt tagggatcgt atataacgat aaattctttg
    14521 atgcaaatca aattaagcat tgggatgatt tgtggaagcc ggaattaaaa gacagtttga
    14581 tgctgattga cggtgcacga gaagttatgg ggctttcttt gaatagttta ggctattctt
    14641 tgaatagtaa gaatatggca cagctgacag aagcagcaaa taaattgaat catttaacac
    14701 caaatgtcaa agcaatcgtg gcagatgaga tcaaaatgta tatgatcaat gaagaagcct
    14761 ccgtggcagt gacattttct ggcgaagctg ccgatatgat gtgggaaaat gaacatttac
    14821 attatgtgat cccaccagaa ggatccaatc tttggtttga taatatcgtt atgccaaaaa
    14881 ccgtgaaaaa taaagaaggt gcctatgatt tcatcaactt tatgctagaa ccggaaaatg
    14941 cggcacaaaa tgcagagtat attggttatt ctacaccaaa tgaagaagca aaagcgttat
    15001 tgccaaaaga catttcgtcg gacgaacaat tctatccatc tgatgacacg atctcccatc
    15061 ttgaagtcta caaagatcta ggatcgaaat acctaggcat ctataatgac ctattcttag
    15121 aattcaagat gtataggaga taatggcaaa actcagtaag aatggggact tatcaacgtt
    15181 ctaaagagct aaaaatcgtc ctttttctat ctgagttttc caatcttcta ccaaaagcgg
    15241 atgaaacgcc gctttttttg tgttatttta ttttttctac cacgtttttc taccagagaa
    15301 aagtggacaa aaccattgta aaatagggcc cgagacgggc tagtaaatct aagattgaaa
    15361 aagttacaga aggataaagt aattggaaac tatgcaaata tacttaaccc ttctgtaatc
    15421 tattaataaa actaatatat gaatccagtt caatatttgt agctatgaaa aaacataaaa
    15481 atcatattag ataaaaacta aattggtaga taaattattt tgtcagatat ctgaggcaaa
    15541 tattcgacta tttgtgtttc aaagtaaaaa ttggaataca aatatagaat agacatattg
    15601 cagccgatag tttattatgc ttttagacac attaaactgg aggaaaaaat gaaaaagagc
    15661 gctaaagatc gagtttttga tgagctgata cgactaacag ggaatatgtc ttctgtcact
    15721 gccgagaaaa tttcgaagaa tctaggtatc tctcgtcaga atgccagcca ttatttgacg
    15781 agattagtgg aagataaaaa ggtcgagaaa ttaccgggaa agcctgtttt gtggaagcct
    15841 ttagatgaat atgcggttgt agataatacg gagcaaataa acgaagcctt tcattctgta
    15901 gttggtcatg acggaagtct gagagaggtc attcaaaaat gtatagccgc tgtcaaatat
    15961 ccgcctaacg gactcagtgt attaataaat ggagccacgg gtgttggaaa aagtttttta
    16021 gccacaaaaa tttttgaata cgctatccat gagcaaatta ttgaaaaaga tgcaccattt
    16081 gctatcttaa actgtgccga ttatgcggac aatcccgaac tgctttcggc aacactgttt
    16141 ggatacaaga agggggcctt tacgggggct gaaaaggata ccgatggttt attggcaacg
    16201 gccaacaacg gctatctttt tctcgatgag gtccatcgcc tatcgaaaga aaatcaagaa
    16261 aagctctttc tatttattga tactggaaac tatcgtccag tcggtgaaaa tgtaaattgg
    16321 cattctgcta aggttcgttt tattttcgcc acgacggaaa aaggtgaaaa ttatttatta
    16381 gacacctttg atcggcgtat tcaaattagt gttatgttgc caacttttga agatcgcccc
    16441 attcgagaac gattagagct gattcaatta ttttttcaaa atgaagcgga tgttttacaa
    16501 aaagatatta ttgtttcaag agaagccttg tctttaatgt tatctcatcc ctttagtggg
    16561 aatattggta agctgaagaa tatcattaaa atcagttgtg cggatgtgta tagtcgaaca
    16621 caagaagaac cattaacgat tgggaaaaat gagatcttga ttcagttaaa tatgctggaa
    16681 tccgaagtag aaagcttgcc gattgctagt ttattgataa agaaaaatca aaagataaaa
    16741 acggatcgaa tcaaaccgtt tgattatgat tcgattttgg aaaaaattac tcagctgata
    16801 aatgaaggta atttcaatga aaatttttct tcgataaaga atgaagtaca gcatttggtg
    16861 catcacattg ataaggattc ttttttatca atgagtagaa aattgatgat tcagatgttt
    16921 agaaaggtct gggtatccgt tttaggaaaa acgtacggat tgacgacgag tggacctgtt
    16981 gcagaaatta ttagcagatc ctatgtcatt tccccaagct ataagacaga cttaaccggg
    17041 ataaatcgta cattagctgc aaatctacct cggacgactt acttatgtaa tcagttcttg
    17101 gagcatttac caccgctctc agaaaaggac gagaactttc taagactgct tattgtcgtg
    17161 actttatctg attatgtaga tgaatccatc gagctgaagg gcctgttgct tgctcacgga
    17221 gatagtacgg ctagcagcat tcaagcagta gtgaatcaat tatgcggcaa ttatgttttt
    17281 gaagcgttgg atatgccagt agagagtaat gtgtcagaga ttgtcgaatc gacaaggaat
    17341 ttcgtgaaac ggcaagtgaa tacagatagt ctagtgctga tcgtagatat gggctcttta
    17401 aatcaaattt acacacagat caagaacgat ttaaaagggg agttacttct tctgaataat
    17461 ttgacgactt ccattgcact tgatattggc ttgaagatga cgatgaatgc gccatttaaa
    17521 cagattgcgg aggatgcagc agacaagtat tcaatcaatg ttcaatactt tgaaggcttt
    17581 tctcaaagta gcaacattat catttcctgt atgtcgggtt tggggatttc ggacaaattg
    17641 aaagatgttt ttcgtcatca tttatcggat gaatccatcg aagttttcac gaaggactac
    17701 agagaactac gtgaattaat cgaccaaaat gatgaaactt attttgacaa gacaaaattg
    17761 gtcatcacga cttcggatct tccacgttcc ttttcaattc ctaatattaa tgtttatgac
    17821 atcttagacg gtgatggagc agccaatttg gagcatattt tgagtcctga aatgaagccg
    17881 gcagaattta accgcttgat tcaggagcta gtaaaattct tttcgttgga aggaattgcg
    17941 gaccgtttga actttctgaa cccaacgatc gtgatgagtg aagtggaaac agtcatttct
    18001 aaatatgaaa attactatca tttcacttta aatggccgtg taaaactaaa tctctatatg
    18061 catacggcat tgatgatgga acgtttattc ttggctcgga cagaaaaatc tgaagaaccg
    18121 aattatgatt tgaaaccaga tgaagatgaa ttttattatg tttctagaag tatttttcaa
    18181 tcaatggaga tgaaatataa ttttaaagtc aatgcttatg agctttcgct gctctatgaa
    18241 ttattaggac cgtatattca aaaataaagt gtctaaaaaa gtgtctaatc tgtttttttt
    18301 aggttagaca ctttttttaa tgtgaattaa cgtgattaaa ccaatgtttt taaaagttgg
    18361 cacaggaatt gcttatataa aagtgaacag aaagaaagga attaaccata tgaagaaaat
    18421 tctaatagcg actcacggtc acttagcttc aggctttctt agcagtattc aattactgac
    18481 ggggaaggtt caagagatta cggtgattaa tgcttatgtg gatgagtgtg attttgaaca
    18541 ggagttgaat gtatttgtaa accaggtgaa cgagcaggat cagatttttg tttttaccga
    18601 tttatttggc ggaagtgtca atcagaagat taccaaaacc tttttggaga aagagattgc
    18661 tgtaactatt ttgtctggct ttaatctgcc aattctgctc gaaatagtat tggcaaccaa
    18721 ggaattaaca aaggaggata ttcaggaact ggtaaataaa tgccaacagg aattaaagat
    18781 gaccattctt gatgaggtac atgtagtaaa tgaagaggaa gatttttttt aggaggaaga
    18841 aaaatgatta aagcagtgcg aattgatgaa cgattaattc atggacaagt agcgatgact
    18901 tggacaaaga gtctaaattt aaccgggtta gtagtagcaa gcgatgaggc ggctaccaac
    18961 gatattcaaa agatgacatt gaagatggct gcaccatcga atgtcaaagt cattattaaa
    19021 acagttgatg acgcgattca tttgttaaaa gatccgcggg cgaaggacat gcgcttgatg
    19081 gttttagtcc ctaatgtcaa agatgcggta aaagttgcga aagctttccc aacggaaatc
    19141 gaattaatga acgtggggaa tgctgggaaa atgacaccgc catcggaaga taagaaaacc
    19201 ttatcaaagg aagtgatgtt aacgacgtca gaaattcaag acttaaaaga attagttgaa
    19261 ctttatccag ataccgtttt tcagcctaca ccggcgatgg aaaaacgttc agctatctct
    19321 attttgagtg atttttagaa aaaggaagga gaaaaattat gtatgatgca tttgtagtcg
    19381 ctttggccgt ttttattgga gttgctggac atgaaatgtt cgggatgtcc atgctgagtc
    19441 gtccgattgt tgttgctccg ttagcaggag cgttgatggg ggatttgcag acggggttga
    19501 ttgtcggggc gtcactagaa gccatcttta tgggtgtcgt caatatcgga atctctagta
    19561 cggcggagcc ttctttggct gctgggctgg ctacagcgtt cgcaatcaaa atgggaggaa
    19621 acgtggatgc gattattccc attgtctttc cactagcagt attaggatta cagttaatga
    19681 atatgatttt ttcttttgta tgtggaccga tggctgctaa atttttcaaa tttgcaaaat
    19741 ctggtgatca aaaaggaatc atcaatctgc acttctttat gtggtttgtc cactatgcgc
    19801 tttatgctct tattccattc tttgccgttt tatttggagc agatgttgtc aaaagcgtct
    19861 tggataatat tccagaggtc atcatgaacg gattaacagt cgctggaaat ctgctgccgg
    19921 cagttgggat ggcgatgctg ttacggatgc tttggagtaa aaatattgct gtgtggtttt
    19981 tctttggggc cgttgttatg gcgtatctcg agttaccatt gattgcaatt gccgcagttg
    20041 gaacgattat tgcaattgtt atagcccaaa gagatctaca actaaaaaat atatctgttc
    20101 atgcagttca aagcgatgct gctgtaaatg caacgcttga ccaagaagag gaggatttct
    20161 ttcaatgaaa ttagctgatg gaatttctaa agatgagaaa aaattggttc ggaagatgtt
    20221 ttggcgctcg atgactatgt atgcttcggt gaatccggtg acgatgggcg gcggtggttt
    20281 cgcctattct atgatgccct tcattaatca tttctacaaa agtgaagaag atcgagctgc
    20341 ggcgctggaa cgtcatacac agtatttttc gacgaccatt ccttgcgcgt cctttgtcat
    20401 ggggattgcg gcatcgatgg agaaggaaaa ttctgaaaaa gctggttttg acgtggaaag
    20461 tatcaacgcg atcaaaacga gtttgatggg accattggct ggaattggcg attcattgtt
    20521 ctggggagtt tggcgtgtcg ttaccgcggg actagcgatc aacttagcca atgccggaaa
    20581 tattttggca ccaattatct ttttagttat gttcaatata cctaattact tgatgcgata
    20641 ctatggcggc gttttaggct attcattagg ctctaaatat attgaaaagc tgtatgcgaa
    20701 cgggttaatt gaaattctga caaaagctgc tagtatcttg ggtctgatca tggtaggtgc
    20761 aatgacgatc agtatggtca aattcaatac cgttttgagc ttttcaatga agggcgaaga
    20821 actaatgaat gtccaagaaa tcctcgatag tatttttaaa ggaattgtac cgttattggt
    20881 aacattgagc tgtttcaaat tactagataa aaaagtcggc gtcatcaaaa ttatttttgg
    20941 aatggtcgtc ttgggaattt tattgtcatt acttggaatc gcatagtagg aagctgcagc
    21001 tactaggctg cagttttttt agcaaggagg gaaaagatga ctattaatga agtaatttat
    21061 tcacccaaac acccattttt taatgctgag ttaaacgacg gaaatgtgac tacttcaaac
    21121 gaatacagct actatcggaa tattcctgat gtaaagggat tgaccttcga tgtaagtaat
    21181 caaaagacat tagcaaacct tgatgtttgc gggacgattc aaacgttgac cttttatcga
    21241 gaaaatttac taactgagga aaaaccaggt gtttgggtca ataaacagct ctctcaaacc
    21301 aattcgttat ccttaaaggt tgaagtaaac gggattgtct accatttgtc agaatcggat
    21361 catcgtattg aagtcgatgt gattcaagac tgtttgccta gatatattca tcattattcg
    21421 acgtttaagg tcattgtagt atcctttgct cccatactgg ctaataagcg tttaagtatg
    21481 cttgttcaac aggtttacat tgtgaatgaa acacacgaaa gccttcaagt ttcagtgaaa
    21541 gatgtgcctt cgtatcaaga gaagtattcg gatcagcaaa atgtgttgat ttctcaaaaa
    21601 ggaaataagg acacgatcgc acaacaggaa gtggcaagct tcgccattgc ttttgtggac
    21661 ccaaatgctt ttgaagaagt aatgactttt caggaatctg atatcgaaaa atggctgaag
    21721 gaaacattga actattttgc tcagctattt gggcagctgt caatgccaaa cgatagagtt
    21781 gtccatctct atcgtcgtgc actttatcaa agcttttcta gtttcggtat gaatcgacag
    21841 ggacaggtcg tcggcagcaa ttggggcagc tatcctgcta ctaatcgaat ttggaataag
    21901 gatatgtatt acgcatcatt gccattcacc atgtttgaac cggagttatg tcaaaaaacg
    21961 gttctatggt ttgatcaata tggcgttaag tttcctggtt caaaatttac aggaggtatc
    22021 aatcattctc tgagtaattc gttatccagt gcgttactgg ctagtcttta ttttgaacat
    22081 actggggata caaaattctt tgagcggtgt ccgcaggttc tactgaatgc ttcaagaatt
    22141 attgaggaca tattagctca acgtcggtca ggggaaccaa tgctttttcc atctgtttgg
    22201 ttatcagacg cctttgcact tggaaagtat cataccggca gcaatctttg tctttggaag
    22261 gcctgtattg gacttgcaga aatttttgaa gccctagaac aactgagtct tagcaagcga
    22321 tacaaaaaca ttgcctgtaa actaaaggaa tcaatttgta aacaaatgac tatcgatggt
    22381 ccttttggtg agcaattttt ggagggaatc ggtgatgagg agaaaacaac ctattcagtg
    22441 aagcactatc aaaaaccgat tcttgagcaa gggttaatct ttttaagtga tgtgattgtg
    22501 gatggaaaaa ttaatttatt gatgcatgat ggagaagaat cagacactac gttgatgcct
    22561 ttttatcaat ttttagataa taaagatcat ttatatcaga acaccatggc cttttctgct
    22621 agttctttca atccaaccta tagcgaggaa atcaaaggca tcacttgggg attagaatcc
    22681 ggcgccactt ttcctggctt tatcactgtt ttaatgagcg agctgcacaa ccctcaagct
    22741 ttcgtaaccc gattagaaga actaatttgt ttggcagatt tagacggttc gtggtggtgg
    22801 tggccgtatc gcttagaggc tcaacaagga gaagtcgtgc gagactttgg ctgcggcaaa
    22861 tgcggctggg catcgggtct ttttgtcagc ctaatgatca gtcaatattt cggattgaaa
    22921 ttcaaaaaag gagtattgca aattgatcct gttgataatt taacgttttc ttggaagaat
    22981 ttgaagttcg gtcaagcctt catttcgatt gaatgtacgc aatccgagtt gagtatttca
    23041 aatttgtcag aaaagccatt gaaaataagt gatacgaaaa aaattcttca cgtagaaaag
    23101 ggaaaaacga ttcacattca aaggagaaaa agatgagtat actaaaaaat attacccaat
    23161 ttaaaaaaat ccagagtcga gcaatcactc ccgaaaatcc aacaggcgag aaaggtaaag
    23221 ctgcgatgtt gccaagcgag ctaggaccaa gccgcaaagg tcgtggcgca attccgctga
    23281 cttctggtga agaaactgtg attgcggata ttactggaac gggaataatt cgtcatatgt
    23341 ggatgacgat tcgtgatcga acagaatttg gcagttttgt tttacgtgat ttaatcttaa
    23401 gaatttattg ggatgggtcg gatagccctg ctgttgaaag tcctttaggg gatttctttt
    23461 gtaatgggtt tggagagcgt tgcgaggtga actcgttgcc gatagtggtt aatcctacag
    23521 ggggctttaa ttcctatttc gaaatgcctt tccaaacatc cgctaaaatt acgatcgaga
    23581 atttacatcc gaaggatatg tcctcatttt tttatacgat aaattacgct ttggtggacg
    23641 aattggaaga aaatagccta tattttcacg caaattggca tcgggaacgc attaccaaat
    23701 tacaggagga ttataagtta attgatcgat taaagggtca aggctattac gtgggtactt
    23761 accttgcgct tacctgccta gaacgttatt ggtggggcga aggcgagttt aaattctaca
    23821 ttgatgggga tagtgagtat ccgaccgtaa cctcaacagg ttcagaagat tattttggcg
    23881 gggcgtgggc ctttcatgag tacgatgagt tcggacgtcc acatgcgaaa aactattcaa
    23941 cagccttttt agggtatcct taccaatcaa atagagatgc cacaagagat cgttttgaaa
    24001 cgggaaaatt gaatgccgtt catgcctttg gtgacgacgc aatgccacga catggtcttt
    24061 atcgttggca tcttcaagac cccatctgtt ttaccgaaga tttatcggtc actttacaac
    24121 aaatcggcaa cgatgatgtt cgcttatttg agcggcaaga cgatgttgct agtgtcgctt
    24181 actggtattc aacagaagct tcaggaaata ctaaacgtca tttcactgat cgagaacgct
    24241 tgccgcgtta atgaagtgtt tttcacatat tcgaagggag gaacctatga tgatatatgg
    24301 ggcaattgaa gctggaggga ctaaatttgt ctgtgcagtc ggtactgagg aattaacgat
    24361 tttggaaaga gtcagttttc ccacaacaac tccagttgaa acaatgaagc aggtcattga
    24421 tttttttaaa ccttttaagg aacaattggc aggcatcggg gtcggctgct ttggtccaat
    24481 tgatattcaa tgcaaatcaa cgagtttcgg tcatatcaca tcaacaccaa aacttgcttg
    24541 gcaaaatttc aattttgtag gaacgctaaa gcaatatttc aatattccga ttgaatggac
    24601 aacagatgtc aatgcggctt gctatggtga atatgttgct ggttctggca aagggttagc
    24661 aggtgttgca tacttcactg tgggaacagg tatcggaggt ggtgccttgt tcaatgggac
    24721 tttcgtggaa gggttcagtc atccggaaat ggggcatatg ttgatcaagc gacatccaaa
    24781 ggacaatttt tcaggaaact gtcccttcca ccaagattgt ttagagggga tggcagcagg
    24841 accagcgatt gaaaaacggt tgggtgtaaa aggccagaat ttattggctg acgattcgtt
    24901 ttggcagatt gaagcctttt accttgccca atgtgcatac aatacaacac tgatgttttc
    24961 gccagataga attatttttg gcggtggtgt aatgaaacaa gaacacatga agaaaaaagt
    25021 tcaggataaa tttgttgagc ttataaatgg atatgttgaa ataccaccaa ttgatagcta
    25081 cattattacg cccgaattag gtgataatgc cggaataatc ggcggattag cattggccag
    25141 aaaagcggta agaaataagc aaccataatt aatgaatgtt tcattgatac tcatgtcaaa
    25201 agtatttaac cgagtaatca aatgatcaaa tgaagttgga taaagcgaaa atgaattcaa
    25261 ataaaaaggc tctaagtcaa atcgtgttgt tttcattaaa tcactgaaag gaaatgcttc
    25321 tgcgtttcct tttttctttt tgttgtgcgc tgtatacctt gaggatattc actggtggcg
    25381 tacacttaaa tagtaatata ttgtgttact ttatgtctgt ggtaatagtt atagttgctt
    25441 accaatgtat gttcattttt cgaaatgttg acttcataat ccttggctta atgtttgaat
    25501 ttttttggtg atagattttt tcagccgtat aaaataaat
//
LOCUS       DAFLWZ010000037        25348 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000037 DAFLWZ010000000
VERSION     DAFLWZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.037"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(122..499)
                     /locus_tag="L1V38_001619"
     CDS             complement(122..499)
                     /locus_tag="L1V38_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316172.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /locus_tag="L1V38_001620"
     CDS             755..1483
                     /locus_tag="L1V38_001620"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBN1316173.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="L1V38_001621"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="L1V38_001621"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBN1316174.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="L1V38_001622"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="L1V38_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBN1316175.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="L1V38_001623"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="L1V38_001623"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBN1316176.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /locus_tag="L1V38_001624"
     CDS             4618..6057
                     /locus_tag="L1V38_001624"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBN1316177.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6080..7132
                     /locus_tag="L1V38_001625"
     CDS             6080..7132
                     /locus_tag="L1V38_001625"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBN1316178.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="L1V38_001626"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="L1V38_001626"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBN1316179.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="L1V38_001627"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="L1V38_001627"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBN1316180.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="L1V38_001628"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="L1V38_001628"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBN1316181.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="L1V38_001629"
     CDS             10651..11565
                     /locus_tag="L1V38_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1316182.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="L1V38_001630"
     CDS             complement(11698..13263)
                     /locus_tag="L1V38_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1316183.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="L1V38_001631"
     CDS             complement(13256..14707)
                     /locus_tag="L1V38_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1316184.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="L1V38_001632"
     CDS             complement(14721..15737)
                     /locus_tag="L1V38_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1316185.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /locus_tag="L1V38_001633"
     CDS             15957..17045
                     /locus_tag="L1V38_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBN1316186.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /locus_tag="L1V38_001634"
     CDS             17099..18625
                     /locus_tag="L1V38_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBN1316187.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /locus_tag="L1V38_001635"
     CDS             18627..19832
                     /locus_tag="L1V38_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1316188.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="L1V38_001636"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="L1V38_001636"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBN1316189.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="L1V38_001637"
     CDS             21330..22754
                     /locus_tag="L1V38_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1316190.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="L1V38_001638"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="L1V38_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBN1316191.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="L1V38_001639"
     CDS             24327..25304
                     /locus_tag="L1V38_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBN1316192.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8194 a         4316 c         5694 g         7144 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DAFLWZ010000038        24259 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000038 DAFLWZ010000000
VERSION     DAFLWZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.038"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1V38_001640"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1V38_001640"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBN1316193.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1V38_001641"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1V38_001641"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBN1316194.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1V38_001642"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1V38_001642"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBN1316195.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="L1V38_001643"
     CDS             complement(3373..4680)
                     /locus_tag="L1V38_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBN1316196.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="L1V38_001644"
     CDS             complement(4683..5264)
                     /locus_tag="L1V38_001644"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBN1316197.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="L1V38_001645"
     CDS             complement(5836..7128)
                     /locus_tag="L1V38_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1316198.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="L1V38_001646"
     CDS             complement(7125..7748)
                     /locus_tag="L1V38_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316199.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="L1V38_001647"
     CDS             complement(7751..8587)
                     /locus_tag="L1V38_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1316200.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="L1V38_001648"
     CDS             complement(8604..9491)
                     /locus_tag="L1V38_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1316201.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="L1V38_001649"
     CDS             complement(9507..10790)
                     /locus_tag="L1V38_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1316202.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="L1V38_001650"
     CDS             complement(11473..12156)
                     /locus_tag="L1V38_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1316203.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="L1V38_001651"
     CDS             complement(12174..12791)
                     /locus_tag="L1V38_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1316204.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="L1V38_001652"
     CDS             complement(12801..13625)
                     /locus_tag="L1V38_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBN1316205.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="L1V38_001653"
     CDS             complement(13618..14178)
                     /locus_tag="L1V38_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316206.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="L1V38_001654"
     CDS             14352..15308
                     /locus_tag="L1V38_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1316207.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="L1V38_001655"
     CDS             complement(15613..16569)
                     /locus_tag="L1V38_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBN1316208.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="L1V38_001656"
     CDS             16673..17275
                     /locus_tag="L1V38_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1316209.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="L1V38_001657"
     CDS             complement(17363..18862)
                     /locus_tag="L1V38_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBN1316210.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="L1V38_001658"
     CDS             complement(18878..19402)
                     /locus_tag="L1V38_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBN1316211.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="L1V38_001659"
     CDS             19700..20449
                     /locus_tag="L1V38_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1316212.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="L1V38_001660"
     CDS             20440..21225
                     /locus_tag="L1V38_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBN1316213.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="L1V38_001661"
     CDS             21194..21910
                     /locus_tag="L1V38_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1316214.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="L1V38_001662"
     CDS             complement(22012..23046)
                     /locus_tag="L1V38_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBN1316215.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="L1V38_001663"
     CDS             complement(23050..24108)
                     /locus_tag="L1V38_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBN1316216.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7624 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgtaa agtgatttt
//
LOCUS       DAFLWZ010000039        23829 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000039 DAFLWZ010000000
VERSION     DAFLWZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.039"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(53..787)
                     /locus_tag="L1V38_001664"
     CDS             complement(53..787)
                     /locus_tag="L1V38_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1316217.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="L1V38_001665"
     CDS             1114..1524
                     /locus_tag="L1V38_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBN1316218.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="L1V38_001666"
     CDS             1517..2218
                     /locus_tag="L1V38_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBN1316219.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="L1V38_001667"
     CDS             2218..3804
                     /locus_tag="L1V38_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316220.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="L1V38_001668"
     CDS             3823..4044
                     /locus_tag="L1V38_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBN1316221.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="L1V38_001669"
     CDS             4041..4802
                     /locus_tag="L1V38_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBN1316222.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="L1V38_001670"
     CDS             5182..5691
                     /locus_tag="L1V38_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1316223.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="L1V38_001671"
     CDS             complement(5766..6305)
                     /locus_tag="L1V38_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBN1316224.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V38_001672"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V38_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBN1316225.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="L1V38_001673"
     CDS             7318..8169
                     /locus_tag="L1V38_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBN1316226.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="L1V38_001674"
     CDS             8197..8832
                     /locus_tag="L1V38_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBN1316227.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="L1V38_001675"
     CDS             8852..9625
                     /locus_tag="L1V38_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1316228.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="L1V38_001676"
     CDS             10033..10830
                     /locus_tag="L1V38_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBN1316229.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="L1V38_001677"
     CDS             10808..11221
                     /locus_tag="L1V38_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1316230.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="L1V38_001678"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="L1V38_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1316231.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="L1V38_001679"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="L1V38_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBN1316232.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="L1V38_001680"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="L1V38_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBN1316233.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V38_001681"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V38_001681"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBN1316234.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="L1V38_001682"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="L1V38_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBN1316235.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="L1V38_001683"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="L1V38_001683"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBN1316236.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V38_001684"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V38_001684"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBN1316237.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V38_001685"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V38_001685"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBN1316238.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="L1V38_001686"
     CDS             21905..22483
                     /locus_tag="L1V38_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1316239.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="L1V38_001687"
     CDS             22535..23017
                     /locus_tag="L1V38_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBN1316240.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="L1V38_001688"
     CDS             23134..23508
                     /locus_tag="L1V38_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316241.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DAFLWZ010000040        23653 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000040 DAFLWZ010000000
VERSION     DAFLWZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.040"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..506)
                     /locus_tag="L1V38_001689"
     CDS             complement(<1..506)
                     /locus_tag="L1V38_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1316242.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="L1V38_001690"
     CDS             779..3250
                     /locus_tag="L1V38_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1316243.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="L1V38_001691"
     CDS             complement(3353..5089)
                     /locus_tag="L1V38_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBN1316244.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="L1V38_001692"
     CDS             complement(5086..5790)
                     /locus_tag="L1V38_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1316245.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="L1V38_001693"
     CDS             5921..6424
                     /locus_tag="L1V38_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBN1316246.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="L1V38_001694"
     CDS             6384..6722
                     /locus_tag="L1V38_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBN1316247.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIEEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="L1V38_001695"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="L1V38_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBN1316248.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="L1V38_001696"
     CDS             8273..8851
                     /locus_tag="L1V38_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBN1316249.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8855..9376
                     /locus_tag="L1V38_001697"
     CDS             8855..9376
                     /locus_tag="L1V38_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1316250.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9455..10009)
                     /locus_tag="L1V38_001698"
     CDS             complement(9455..10009)
                     /locus_tag="L1V38_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1316251.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10262..10537
                     /gene="rpsP"
                     /locus_tag="L1V38_001699"
     CDS             10262..10537
                     /gene="rpsP"
                     /locus_tag="L1V38_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBN1316252.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10549..10800
                     /locus_tag="L1V38_001700"
     CDS             10549..10800
                     /locus_tag="L1V38_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBN1316253.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10925..11716
                     /locus_tag="L1V38_001701"
     CDS             10925..11716
                     /locus_tag="L1V38_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316254.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11886..12407
                     /gene="rimM"
                     /locus_tag="L1V38_001702"
     CDS             11886..12407
                     /gene="rimM"
                     /locus_tag="L1V38_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBN1316255.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12397..13158
                     /gene="trmD"
                     /locus_tag="L1V38_001703"
     CDS             12397..13158
                     /gene="trmD"
                     /locus_tag="L1V38_001703"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBN1316256.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13294..13641
                     /gene="rplS"
                     /locus_tag="L1V38_001704"
     CDS             13294..13641
                     /gene="rplS"
                     /locus_tag="L1V38_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBN1316257.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14014..14676
                     /locus_tag="L1V38_001705"
     CDS             14014..14676
                     /locus_tag="L1V38_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316258.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14755..17982
                     /gene="fss3"
                     /locus_tag="L1V38_001706"
     CDS             14755..17982
                     /gene="fss3"
                     /locus_tag="L1V38_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1316259.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18096..18410
                     /locus_tag="L1V38_001707"
     CDS             18096..18410
                     /locus_tag="L1V38_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1316260.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18423..18797
                     /locus_tag="L1V38_001708"
     CDS             18423..18797
                     /locus_tag="L1V38_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1316261.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18807..19151
                     /locus_tag="L1V38_001709"
     CDS             18807..19151
                     /locus_tag="L1V38_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1316262.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19222..20574
                     /locus_tag="L1V38_001710"
     CDS             19222..20574
                     /locus_tag="L1V38_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1316263.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20634..21776
                     /locus_tag="L1V38_001711"
     CDS             20634..21776
                     /locus_tag="L1V38_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBN1316264.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21801..22055
                     /locus_tag="L1V38_001712"
     CDS             21801..22055
                     /locus_tag="L1V38_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316265.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            22311..23495
                     /locus_tag="L1V38_001713"
     CDS             22311..23495
                     /locus_tag="L1V38_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1316266.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            23492..23629
                     /locus_tag="L1V38_001714"
     CDS             23492..23629
                     /locus_tag="L1V38_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1316267.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         7833 a         4217 c         5073 g         6530 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgagg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8881 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8941 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     9001 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     9061 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     9121 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     9181 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     9241 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     9301 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     9361 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     9421 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     9481 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9541 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9601 cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9661 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9721 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9781 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9841 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9901 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9961 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
    10021 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
    10081 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
    10141 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
    10201 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
    10261 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
    10321 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
    10381 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
    10441 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
    10501 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10561 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10621 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10681 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10741 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10801 ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10861 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10921 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10981 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    11041 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    11101 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    11161 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    11221 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    11281 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    11341 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    11401 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    11461 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    11521 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11581 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11641 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11701 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11761 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11821 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11881 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11941 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    12001 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    12061 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    12121 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    12181 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    12241 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    12301 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    12361 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    12421 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    12481 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12541 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12601 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12661 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12721 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12781 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12841 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12901 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12961 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    13021 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    13081 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    13141 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    13201 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    13261 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    13321 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    13381 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    13441 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    13501 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13561 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13621 atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa tttgtgaaaa
    13681 gtccttgtat atcaagggct ttttcttttt tctctatcac agttttaagc catttttggc
    13741 tgttttggac catttttcaa tcatattccc ttaaaaattg tcctagattg tccgacattg
    13801 actatcagtg tcgtcaaaat agggcaaaat ttagtagtca gcttgacgac aaatataata
    13861 cgaaaaatac caaaacattt accgaattta gcaacttttg aacccaagtt tctcaaaggg
    13921 tcagctatta gcaaaaaaga caaaacatgt acttttctac taaaaagttg atgtgatagg
    13981 cttctatcta aataactatt aggagttttt atcgtgaagc aaaatgatgg acgtatcatt
    14041 tggaaaaatc aaagtgagtt aaaactgatt ttaacaatta atgaattcat cgaaaaacac
    14101 ggaattacat ctagccgtca ataccagaaa aagctatcag aaaatccaaa ttctgcacca
    14161 agtatgtggt tcattaacaa aaaatatgga tcatgggaga atttattgat tagtatagga
    14221 cgagaaaata ctgggtatgg aaaatgggct agaatgtcag aacaagaatt attggaaata
    14281 gtagaagcct ttattaagtg cgagaagata acctctcaac gaatgtacga acaaaaatca
    14341 gtagggaaga atattccttc acttagtacc attaaaaaga tgttaggaga tatacgtcca
    14401 ctttttaaag aaaaaaatga tggatctcga tttactgatt tcgaactgct gttagaacta
    14461 aaaaatgaaa taatccgatt aaaactacag gatgatttat caatgacaaa gtttcgaaaa
    14521 ctagttcaat ccccaaaact accatcagtt gatacaatta tgaaaagaac gaacaaaaat
    14581 tgggaggaat tgatggcaga gattggattt gattatcgaa gaatcaaaat ttataagcag
    14641 agaaacaacc tatccaagac aaagaaaact aaatagtatc actctaaatc agacgttcaa
    14701 aattaaaatt tggacgtctt ttttattacc caaaaacgaa aggagattta ttttatgaaa
    14761 aagccaagat ttaagaattg gcgtttgctc gcaacactga gtctattatg ccaaacaatt
    14821 ggtggatcgc ttggcccaac gattgccttt gctgatgaaa ttactcatcc acaaacggta
    14881 actgtggaat tggatttggc tcaccagtat gctgtcgaag gtacatttag cgatggtcgt
    14941 cccatgtcag aagttaccgt tccgcactat gcagtttaca atggtgtgaa gcaagatatt
    15001 ttctgtattg agccaggggt gccgatttac aatgagttca ctcctggtta tgagaaaaat
    15061 ccattgcctg atatgtcgga gaaagcgaaa ttagtttccg ttttatggaa ggaagctggt
    15121 acggatgtgg atacacatat tgtggcccag aagatgattt ggcaagaagt taatggctac
    15181 acgcttcact caattaaacg ttctgatggt agtgcagtaa atatcgcagc cattgagtca
    15241 aaaatcaatc aagccattgc ggattatcaa aagaaaccaa gcttccataa ctccacagtg
    15301 aaaaccgtgt taggtcaatc gactactgtg acagatacga acggcttgaa tttatcggag
    15361 tttgatgaag ttgtcgagaa tatcgcaaat attgattatc gtgtgaacgg caatcaacta
    15421 gtgattactc caaatgccaa ttcaaaagag agtggtgaat taaccctaaa gaagtcagct
    15481 aatacaggaa caccggtagc ttataaaatg gctggtcaac aaactttgat ggcgggggca
    15541 attgataagc ccaataccta cacaatcaaa attgatgtgg aaactgaggg ttctttgaag
    15601 attaaaaaag tcgataaaga aacaggaaat gttgtaccgg gaaccgtttt ccatttagac
    15661 tttggaaaaa cattacctgc aaaagacgtg accaccgata aagaaggcat tgcgacattg
    15721 gatgagattc ctcatggcgc gaaagtaacc attactgaaa aatcagtgcc agctccttat
    15781 acgattgaca ctacaccaat caccgcaacc attaaatctg gtgagactat ttctgtgact
    15841 tcaaaaaata ctcgcgaaaa aggtcaaatc attttgaata aaatgggggt ggaaacagga
    15901 actgatcttt ggaacgacaa atactcatta gccggaaata cgtttgccat tcgcaaagac
    15961 agtccaaccg gtgaaattgt ccaagaaatg accacggatg aaaaaggtca tgcggaaaca
    16021 ccaaaagaga ttgccaatgc gttggaattg ggaacctatt atgtgaccga aaccaaagct
    16081 agtaatggct ttgtgaatac ctttaaacca gtaaaagtcg aattgaacta tgtcaatcaa
    16141 accgtggctc ttgttaccag taacgtaaaa gggcaaaacc aagaaatcac tggtgaaacc
    16201 actttgacaa aagaagacaa agataccggt aatgaaactc aaggtaaagc tgagtttaaa
    16261 ggagctgaat atactctctt tactgcaaaa gatggtcaag cggtcaaatg gagtgaggct
    16321 tttaaaccag agttagtgaa gggaacgaaa gcttctgatg aaacggtgac tttgacttta
    16381 gatgaaaaga atcaagttgc tgttaaacac ttagcgatta atgagtatta ctggcaagaa
    16441 accaaagcac ctgaaggata taccttggat gaaacaaagt accctgtttc catcaaaaag
    16501 gtggatgata acgaaaaaaa tgccgtgatt acccgagatg ttacggcaaa agaacaagtc
    16561 attcgctttg gctttgattt ctttaaattt gctggatcag ctgctgggac tgccgaaact
    16621 ggcttcaatg atctgacctt taaagtatcg ccattggaag gaaccagtga gattacaggt
    16681 gccgaagatg aagcaattac agcttataac gagcaactag gttttgatgg ctatggcaag
    16741 tttgaaaatc ttccttatgg ggattattta cttgaagaag tagaggctcc agaaggattt
    16801 caaaaaatta cgccattaga aatccgttct acttttaaag aaaataaagc ggattacact
    16861 aagagtgaat acatttttac gattaccgaa aaaggacaaa aacaaccaat taaaacggtg
    16921 accgttcctt acgagaaact gacgaataaa gcattttctg ttagcttgaa tcgtttgatg
    16981 ctctatgatt tacctgaaga agaagatagc ttaacttctc ttgggacttg gaaagacgga
    17041 ggcaaagaat tgacagacct tgattctacc gagctagttg ataaattgag ctataacttg
    17101 catgaaatca aagaagactg gtatgtggta gcgcaagcca ttgatgtgga agcgacaaaa
    17161 gctgcccaag aaaaagatga aaaagccaaa ccagtggtaa ttgccgaaac aaccgcaacg
    17221 ttggcgaata aagagaaaac aggaacttgg aaaattttgc ataaattaac cgcagaacaa
    17281 gttttggata aaaccatcgt cttattcaac tatgtgtatg aaaacaagaa accctatgaa
    17341 gcaggtgatg atccagtagc gaaagatgct agcttgaaca atcaagccca aactgtcaat
    17401 tgtacggtgg aacgccatgt ttccatccaa acaaaagccc acctagaaga tggttcgcaa
    17461 acctttactc atggggatgt ggtggatatg ttcgatgatg tgtcgattac ccatgatgta
    17521 ctggatggct caaaagaagc ttttgaaaca attctgtatg cattacttcc ggataatacg
    17581 accaaagaaa tttggaaatc tggcaaaatt gattatgaag tgaatgacaa agaattcact
    17641 aaaaccgtac ttgcggaaaa agtggacaca agtaaatatc cagaaggtac aagttttacc
    17701 ttcaaagaaa ttaactatgg caaagacgga aacatcaatg ggaaacacaa tgaggatcta
    17761 aaagaaaaaa ctcaaacttt aacacctaaa aaagttccga caacaccaag tgcaccagaa
    17821 caaccggaaa taccaactgt tccaagtgac tctcaagaat ctagtcctac agtaaagaca
    17881 ttcccacaaa caggggagaa aaattctaat gttctgctgt ttattgggtt taccttgatc
    17941 tttgcgactg ctgggtatta tttctggaat cgccgaaact aaggtgatgt gatgaaacaa
    18001 ctaaatagga aaaaccaacg tgcgcgaccg cctcctaaaa aaagtggtcg cgctattttt
    18061 gtatccaaaa ctaaaaatga aaagaggaaa agaagatgga attgaaattt gttgtgccag
    18121 atatggccga aacctttgga aagataaggt atgccggcga aggcgaagtt ttaactgaag
    18181 gatatgggcg gaatactaca gtaattggtc gtagttatca tttgtattcc agtaagcaac
    18241 gagccgatga tattgaagtg gtggtagctg cggaagccgg cgaaaaggat tttgatcaag
    18301 atcaaccact aaaagccgtg aatccccatt tggttgccaa aggctatgag attgagaatc
    18361 gtgggtttac cgactacgtg ttgtatgtcg atgatttagt gaaagcatag gaggaaaaga
    18421 agatgagatt aacagaaggt attgttgtag attcaggact aacgtttggg aaattacgat
    18481 tttccgcatt acgccgagaa gtacggaagc aaaatgagga tggaacggtt agtaacgagg
    18541 taaaagaacg gacttataat ttgaaatcct ctgcgcaagg tcgaatgatc caagttagta
    18601 tcccagcaaa tgtaccctta cgcgagtttg cctatgacgc agaggtagag ttggtcaatc
    18661 caatcatgga tacggtcgcc aattatgttt tccgagaagg aactactgtc aattggttca
    18721 ttaaggccga tgatttagtc ttgaaacgac aaccagatca gggaaattct acaaaccaaa
    18781 atgaaggaaa gaaataggtg aagcgtatgg aaattaatgt tgaacatatt ttagattgtc
    18841 tcgatcaata tggaaaaggt gagctaacgg aggaacaact cactaaagca ttaacctatg
    18901 atgaaaaaat gtttctgatt atgcatcaag ggttactgga agtaggtaac gatgtcgaag
    18961 aagattttga tgtactgaat tggttagggg aagaagagtc cttctttatg gttatcgaag
    19021 taaatgaaag tctatgtcga gaagccgaaa ccgtattgga agaaattggt gtggaaatgc
    19081 cggatgccat tgaagttttt ttaaagcaac tagtggaaac gaaacaactc cctatagcag
    19141 taaatgacta gcataactgc ttgaaattgg atcaatgaaa tcctatgaag cttttttcga
    19201 ttggaggtgg aaaccataaa aatgtacaaa gggcatcgta tacgggcagg agatcagcac
    19261 ttggtttatc actttgttct tggctggcta ctcgctctgt tcatcggttg gatgagcgtc
    19321 ttttattttc aagagcttag acaatttgat atttctaagc tatcactttc tactatagaa
    19381 atcgttcgtt ctataaaaga tttaatctat ttgctaggaa gtctcgttct ttcaggaagc
    19441 acgatgttgc tttatataca cttttttcag gatcattggc gcagtttgtg gcatcgacaa
    19501 aagctagccc ggatgattct agaaaatcat tggtacgaag taaaacaaac tcagagtgaa
    19561 ggatttttca aagacctcaa tagtagtcga accaaagaga caatcagtta cttccccaaa
    19621 atctattacc gtatgaagga tggtttactt tctattcgcg ttcaaatttc actgggaaaa
    19681 tatcaagatc agcttttaaa gctggaaaag aagttagaaa gtggtctata ttgtgaacta
    19741 gtagaaaagg aactcaaaga ctcctatgtg gagtacactt tactgtatga tataattgcc
    19801 aatcgaattg ggatagacga agtagtggca gaaagtgggg ctttgcgatt gatgaaaaat
    19861 caagtatggg cttatgattc tttacctcat atgttaatcg ctggcggcac aggtggtggg
    19921 aagacttact ttttactcac tatcatcgag gctttattaa aatctgatgc cgagcttttt
    19981 gttcttgatc ccaaaaatgc ggacttagcc gatttaggta cggtaatgcc tcatgtctat
    20041 tcccaaaagg aggaaatttc tgcttgtgtg gaagatttct atgagcgcat gatgactcgt
    20101 agcaaggcaa tgaaagaaat gcccaactac aaaacaggag agaattatgc gtttcttgga
    20161 cttccaccaa actttttaat ctttgatgaa tacgtggttt atatggaaat gttaacgacg
    20221 aaggaaagtg cggtgatttt gaataagctc aaacaaatcg tgatgttagg tcgtcaatct
    20281 ggtttctttc tgattctagc ttgtcaaaga ccggatgcga aatatttagg agacgggatt
    20341 cgcgatcaat ttaatttccg ggtggctttg ggtcgtatga gtgaactggg atattccatg
    20401 atgtttggcg aggttgataa aaaattcttt atgaagcgta tcaaaggtcg aggctatgta
    20461 gatacgggag ggagtgtgat tagtgagttt tatacgccac ttgtaccaaa aggatatgat
    20521 ttcttaaggg aaattagcga cattggtgga ttaaacgtta atacggaagg ataaaataat
    20581 agtatgtagc ctaggagtgt caagaatcct gggctttttt tacgaggtga tttatgacat
    20641 ttttagattt attcgctggg attggtggct tttgcttagg tatggaacaa gcgggtcacc
    20701 agtgtatcgg cttttgtgaa attgatgatt ttgctcgcca gagttataag gcaatccatg
    20761 atacaagtaa ggaggtggaa atgcatgaca tcacaagtgt atcagacgag tttattcaat
    20821 ctctcggacc agtggatatc ctttgcggtg gatttccgtg ccaagctttt tcaattgcgg
    20881 gaaagcggca aggattttcc gatactcgag gtactttatt ctttgaaatc gctcggttcg
    20941 ccgctattct ccaacctaag tttttattcc ttgagaacgt ccggggatta ctcaatcacg
    21001 aaggaggggc tacgttcgag acgatcctcc gaacgctgga tggattgggg tatgatgtgg
    21061 aatggcaagt gcttaactca aaggcctacg ttccccaaaa ccgtgagcgg atcttcctta
    21121 tcggacattc tcgagacgca tgtaccgaac aagtatttcc tatcattgga tcgtctccaa
    21181 catctgatca aaacatcaga aacttattaa atatcaaccc ttccaatcga ggaatggggg
    21241 gacaagtcta tgggtcagat gacgtagcgc ctaccttgac cggtgatgaa ggaatcaaaa
    21301 tcgcattgcc ggtagatgat ggaatttctg tagcgggtat gttactggga aattttgaac
    21361 aaggcaatcg ggtttatgag ataactggaa cagcgcctac tttgtcaacg aaacaaggcg
    21421 gaacgaagat catgcttcgg aaaaacgaaa cagaatatca agaggtgaag ccagggaaca
    21481 gtgtgaacct ggcttttcct aattccacaa gtcgtcgagg ccgtctggga aaacaaagtg
    21541 tgcatacctt attaacagga gaccaacaag cagtcgtcac ggatcagtat caaattcgaa
    21601 agttaacacc tagggagtgc tggcggcttc agggctttcc ggactgggct tttgatcgag
    21661 cttctcaagt caattcagat agtcagttgt ataagcaggc tggaaattct gtaacagttc
    21721 cggtcatttt tgatattgct agaagattaa aggaggtaaa aacagatgat ttatgatgag
    21781 ttgattgggg aatctactgg gtgattggca agattcagtc agatccggaa ttggaagaag
    21841 aactgtaccg gctcaatttt gatattcgca aaaacggggt gaaagtccct gatgatccgt
    21901 atgtaattga tgaggaaacg gatgctcgaa tggagctgaa tcaagtcatc agtgaattgg
    21961 aacgaattgc ggactttgct aaagaacctg atatccgcca atacttgttt gagataaaag
    22021 cagagttgga aattgagggt attaccgcgg agtaacggcc aaataaacca ctgataggca
    22081 ctgaccgcgg gggatttgcg aagcagaaat cctccgtggt gctgtgcctg tttatggacg
    22141 gcgttagccg gccatgatgt ctcacccccc gtatctaaca ggggggtaca aaaacacaaa
    22201 aaataagcaa gcaacgataa ggaatggctg tcctatcaag gataataagc aatttgtgta
    22261 gatgttaact gatttgaaaa agttaacacc ttaaatttgg aggtgagaac ttggcacaaa
    22321 ggaatttaga ttatcggcta ttaaaagacc ggcgtaatga atatggcgtt tcacaaaata
    22381 aattagctac gacttgtgga cttagtcgcc cgtacttaaa tcagatagaa aatggtggcg
    22441 taaccgcatc gacaaaaacc atgaggaaaa tttttgacca actggaaagt ttcaatcccg
    22501 agttaccttt aacgttactg tttgactatg taaggattcg ctttcccaca acggatgcga
    22561 ggaaaatcat tcaagagatt ctccatttga aatttgatta tatgctccac gaagattacg
    22621 ccttttactc ctatcaagaa caatatgtta tgggagatat tgtggtgatg ttgtcacatg
    22681 aagaagataa aggcgtcctt ttagaattaa agggtcgtgg ttgtcggcag tttgaaactt
    22741 ttttactcgc ccaaaagcgt agctggtatg actttttcga agattgtcta aaagccggtg
    22801 gcgtgatgaa acgcttagac ctggcaatca atgatcgagt tggcctgtta gatattcctg
    22861 atttaacgaa aaaatgtcag aaggaagaat gtatctcctt gtttcgtacc ttcaaaagct
    22921 atcgttccgg ggaactgttg aaacctgatg ataaagatgg tatgggcaat actttgtata
    22981 ttggcagtct taagagtgag gtctatttct gtttgtacga aaaagactat gagcaatata
    23041 tcaagttagg gattccttta gaccagaccg aaacgaaaaa tcgttttgaa atccgactga
    23101 aaaatgatcg agcttatcat gcaattcaag atttgttaaa aggtcgcagt attgaaagta
    23161 ccacattttc cattattaac cggtacttgc gatttgcgga taaggtggaa ggcaaaaggc
    23221 gaactaactg gcccttgaat gaacaatggg ggcgcttcat tggacggaat cagaaggaaa
    23281 ttcaattaac ttctgaaccg aagccttata ccattgaacg aacgttgaac tggcttggac
    23341 gacaagtcgc ccctacgtgg aagatggcca aggagttgga tcggttgaat cagacaacgt
    23401 acattcagga tatggtaaat aatactcgac tatcagaccg gcacaaaaag attttggagc
    23461 aacaaagtat ggcaattgaa aatttgatta tatgaaaaga ggaatcgtga tggaaattgt
    23521 gaaagatatt ttattggtgt ttggtggcag tatgcttggt gttactgtga tgtgcttgat
    23581 gcatgcaagt gcagcggcgg accgagcaat ggaaaagaaa ggaaagtgat gaaatgaatt
    23641 tcggtcaaaa ttt
//
LOCUS       DAFLWZ010000041        22729 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000041 DAFLWZ010000000
VERSION     DAFLWZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.041"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(22..1953)
                     /locus_tag="L1V38_001715"
     CDS             complement(22..1953)
                     /locus_tag="L1V38_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1316268.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1971..2885)
                     /gene="pfkB"
                     /locus_tag="L1V38_001716"
     CDS             complement(1971..2885)
                     /gene="pfkB"
                     /locus_tag="L1V38_001716"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1316269.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2882..3634)
                     /locus_tag="L1V38_001717"
     CDS             complement(2882..3634)
                     /locus_tag="L1V38_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1316270.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3793..4002)
                     /locus_tag="L1V38_001718"
     CDS             complement(3793..4002)
                     /locus_tag="L1V38_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316271.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4013..5340)
                     /locus_tag="L1V38_001719"
                     /pseudo
     CDS             complement(4013..5340)
                     /locus_tag="L1V38_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5476..5631
                     /locus_tag="L1V38_001720"
     CDS             5476..5631
                     /locus_tag="L1V38_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316272.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5705..6292)
                     /locus_tag="L1V38_001721"
     CDS             complement(5705..6292)
                     /locus_tag="L1V38_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBN1316273.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6375..7625)
                     /gene="clpX"
                     /locus_tag="L1V38_001722"
     CDS             complement(6375..7625)
                     /gene="clpX"
                     /locus_tag="L1V38_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBN1316274.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7872..9161)
                     /locus_tag="L1V38_001723"
     CDS             complement(7872..9161)
                     /locus_tag="L1V38_001723"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBN1316275.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9315..10247)
                     /locus_tag="L1V38_001724"
     CDS             complement(9315..10247)
                     /locus_tag="L1V38_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316276.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10404..11063)
                     /locus_tag="L1V38_001725"
     CDS             complement(10404..11063)
                     /locus_tag="L1V38_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1316277.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11066..12091)
                     /gene="sppA"
                     /locus_tag="L1V38_001726"
     CDS             complement(11066..12091)
                     /gene="sppA"
                     /locus_tag="L1V38_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBN1316278.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12104..12394)
                     /locus_tag="L1V38_001727"
     CDS             complement(12104..12394)
                     /locus_tag="L1V38_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316279.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12803..14608
                     /gene="glmS"
                     /locus_tag="L1V38_001728"
     CDS             12803..14608
                     /gene="glmS"
                     /locus_tag="L1V38_001728"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBN1316280.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14680..16035)
                     /locus_tag="L1V38_001729"
     CDS             complement(14680..16035)
                     /locus_tag="L1V38_001729"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBN1316281.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16059..17228)
                     /locus_tag="L1V38_001730"
     CDS             complement(16059..17228)
                     /locus_tag="L1V38_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316282.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17225..18112)
                     /locus_tag="L1V38_001731"
     CDS             complement(17225..18112)
                     /locus_tag="L1V38_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBN1316283.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18301..21993)
                     /gene="nifJ"
                     /locus_tag="L1V38_001732"
     CDS             complement(18301..21993)
                     /gene="nifJ"
                     /locus_tag="L1V38_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBN1316284.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22192..22713
                     /locus_tag="L1V38_001733"
     CDS             22192..22713
                     /locus_tag="L1V38_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1316285.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6327 a         4938 c         4044 g         7420 t
ORIGIN      
        1 ccagcctctt cttttttatt tctatgcttc tgctactgca ggagcttttc tcaataaacc
       61 ataaatcaca ccagatacga ctgctccgat agcaataaac accaaataca tgaccgggtg
      121 actcagtaag aatacaacga aaatcccgcc gtgaggagcc agtaatttga ttccgaaagc
      181 tccgactaat ccgccagtta aagcagaacc aataataaaa cttggaatgg cacgaatcgg
      241 gtcagctgct gcaaatggaa tcgatccttc cgtgacaaac gatagtccca tcacgatgtt
      301 cgtcaaacca gcatcttgat ctgttttgct gaatttattc ttaaacaaac gtgtagcaac
      361 gaaaattgcc aatggaggta ccattcctcc agccataaca gaagccatca cgacacttcc
      421 gccagttgca acagtcgtag ctaaagttgc tgtaccaaac acataagcgg ctttgttgat
      481 tggaccgcct aaatctgccg ccatcattcc agctaataat gcaccaagta aagcagcatt
      541 cgaaccactc atacttgtca agaaaccgtt caatgcatca ttgattgctt tcatagggac
      601 attgaccagc aacatcaaga aaccagtaat cagtaagcca aacactggat aaaagaggat
      661 cgttttaatt ccatccaatg attttggtaa gttcttgaat aatttacgta aaaatacgat
      721 gacataacca gctaagaatc caccaatcag tgcacctaag aatcctgcac cgcctgtatt
      781 agctaatgca ccagcagcaa atccaacgat caaaccaggg cggtcaccga tacttgaagc
      841 aataaatcct gctaataccg gcagcatgaa accaaatgca gcttgtccga tttggttgaa
      901 ccagctagca gcttgattgt aattccctag atttgataat tgatcatgtg gcacgccaat
      961 aaattggtcg atcatgaaag aaagcgcaat agcgattcct ccaccaataa cgaaaggtaa
     1021 catgtgtgat acgccgttca tcaaatcttt gtaaattctt tgtccgatag taccatccgc
     1081 atttccttct tctgaactgc tttcttttcc atcaccatgg aatactggtg cagtaccact
     1141 aagggctaga ttgatcaact cttctggttt acggatacca tcactgacag gacgattgat
     1201 cagttctttt ccgtcaaagc gattcatctc tacttttttg tctgctgcaa cgattacacc
     1261 ttctgcacgg gcgatgtctt cagcagtcaa tcggtttttg attccttctg aaccgttcgt
     1321 ttcgactttg atctccacac ccatttcttt cgcttttttc ttcaaagcat cttctgccat
     1381 gtaagtgtga gcgatccctg ttggacaagc tgtaacggca acaacgaatt ttctttctgg
     1441 atgagcagaa gcttctgcag cttgtgtttc ttgttctgct ttttcttctg cttctttttg
     1501 ctcttcagct gtttggaaca agtcttggac ttcttctggt gtatttgctt cttttaattt
     1561 tcctacgaaa tctgcatcaa tcagcaatcg agatagtgct gctaatgctt gcaaatgtgt
     1621 gtcgtttgcg ccttctggag ctgcgatcat gaaaaacaga taagttggct gtccgtctaa
     1681 ggcttcataa tctactcctt tttggctttt tgcgaataaa actgttgctt ctttaactgc
     1741 actgtttttc gcgtgaggca tggcgattcc atcaccaaga cctgtagaag tttgtgcttc
     1801 gcgggctaga attccttctt tatatgtttc gatatcggaa atccggccgg catcaaacat
     1861 tttttggacc atttcatcga ttgcgccttt tttatcagtc gcttgcaaat ccatgatcat
     1921 cgcttctttg accattaaat ccttgatatt catgattatc ctccttgaaa ctaatcaatt
     1981 tttgtgattt caacttctgg cagcaactca tcaatcaatt cgcgagctgc caagtcatca
     2041 gaaaaagctg ttgcgcttcc gcaagcaact ccccatttaa aggcttcgat tggatctttc
     2101 gtacggctgt aagccccaat aaagccagca atcattgaat cccctgcacc tactgaattt
     2161 ttcaatgggc gaactaatac attcgtttta taagttcctt gttccgtgaa gagcaaagca
     2221 ccgtctccag ccattgagat cagcacattc tgtgcccctt cagctagtaa ttttttccca
     2281 tacggaatga tttcttctac agattggaag gttgtgttgt aaagctcagc taattcgtga
     2341 ttgtttggtt tgatcaacaa cggtttctta acaagtgcat tttttaggtc atcacctgtt
     2401 gtatcaatca cgaaatctgc acctttttct cgaatgatat caatcagttc ttgataaaat
     2461 ccttttcgca ggctagctgg cgcgcttcct gacaatacga cgatatctcc ttgtcctact
     2521 gttcctaatg cttgcttcaa ctcatcgatt tcttcatctg aaatagatgg gcctaagcca
     2581 ttgatctcag tttcagtgtc tgattttagt ttgatattga ttcttgtatc ttcttttacg
     2641 gttgtgaaca aagactggat ttgttctttt tcaagccact tcgaaataaa ttcgccagtg
     2701 aaccctccta aaaaccctag tgctgtagat tgagaatcga tccgtttcaa aatacgggaa
     2761 acattgatcc cttttcctcc aggtaacttg aagtcttcct tcattcggtt caaatcgcct
     2821 agttttaacc catctacgcg tacgatataa tcaattgatg gattaagtgt tactgtgtaa
     2881 atcattgtat tgcctcctta attgttgtct tttcacggaa ttcattaacg aattctaatg
     2941 gacaacgctc ggttatgatc gtggctgctt ccaaaggtgc aacagaggtg aaggacaact
     3001 ggttgaattt ggtatgatca atcaatacaa atgtctcttc ggaatttttc atggctaaac
     3061 gtttaacagc tgcctcttct ggatccggag tcgtgaatcc ttgttcaaga tgggcaccgt
     3121 tcattcccat aaatgcttta ttaaaatgaa aattttttag ttgttctatc gcattagatc
     3181 ctaaaacagc attagttgcc agctttatcg ttccacctaa aataatggta gcaagctcca
     3241 aatcaactaa atttgccgca tgttgaacgg aatttgtcac tactgtgatc tgttttcctt
     3301 gcagaaaagg aatcatttct aacgtagtag agccagcgtc taaataaatg acatcttcgt
     3361 cattaatggt ttcagctgcc gatttggcga tttgctgttt ttcgtgaacg tttttgagtg
     3421 atttttcact catattctgc tcaaaattca ataattgctc tttcttagct ccgccatgaa
     3481 ctctttctag aaacccacta ttctccagct cttgtaaatc acgtcttatc gttgattcag
     3541 aagcattcaa aaggtttaca agatcttgtg atttcacgat tttctgctgt tcaagcaagt
     3601 ctaggatttt ttgtctgcgt tcctctgtaa gcattttcac gatcacctca atacaaataa
     3661 tagcatattt tttttctact agcaatataa atcagtcaaa aacgttcata aaaattataa
     3721 atcagtcaaa aaaaaataaa aaaccagtca gaaagactgg ttttttattt ttttgtctat
     3781 catcaagccg ttttatcgtt ttttattttc gcttcttgtt tttttcatat aaacagaagc
     3841 aggttttctt tccttatgaa gaagataata ataaagtccc atcccgccaa acatgaccaa
     3901 aaaaccgatg actgatcgaa taggaaaatt aggaacaaaa aagagacaga cggataataa
     3961 tgatgccgga accattattc gataatagag ttgtttatcc attttcttca cctcatattt
     4021 tttgtaaagt aatcaattgt tctaattctc ggtaatctaa aaattgcaca cgcagatgct
     4081 gctcaccttt cttgacatcg aattggatac ttcgccgctt tttctttatt cgtttgaagg
     4141 taacatcaga gagtctatgt ttgatttcct ttaacggtaa ttctgacagg gattctgaag
     4201 gaacatagat tcttaaggat aaaagatact cttgatattt ttcatctgtt acctctactt
     4261 ctagatattc cctaatataa taacaataag cttcgattcc attatccaaa gcaacagtcg
     4321 gatcgataac tttatagcac atcatgcgtg atcgattctc gtcaacccaa ggaaaatacg
     4381 cctgagcatt tagtgttccg cgaacacgcc tttctttata atctccttgt tggatatcat
     4441 aactttttgt tacaaaaaat gaagcattct ttttaggaac aggttgcatt tgtgcattct
     4501 gatactggac agattggatc gtatggtcag tgtaaatgta ttcaacgaat ggcggtttca
     4561 ataaaccgac accattgtcc caagcaagat gatcaaaccc aagctggtcc ctaaaatagg
     4621 attgaaacat ttgattgttt ggcttttgcc agttaaaggg gtctcgataa agctggatac
     4681 atatgacttc gttttctaat tccttcactt tttctacttg ttggatgtcg agaaaaatcg
     4741 gtttagggat gatttgatga taatagcgac tataatacat ttcccaacac gaagtgaaac
     4801 ataaaccttg gtaaaaaaga tcgtatcctg gaaattggtt gcaatcgact actacttccc
     4861 cgttttgttg tttcatttta ggtaaatgtt cgatttcatc ctttttctca aacaatagcc
     4921 gttgagagat ctgttttgta ttgtgataga taaactcgct ataagctcgc atataggcga
     4981 acaccccatg agcaatcatt tttttctgaa tgaagtctcg aatcaaaaat tgcttttctt
     5041 tgaaaacaga gatagacaat acatttttta tcaataattg attatcttcc aagcgaaaac
     5101 tacattcgtt ctcgtcattt cctacaacta accaactttc gtctcttacc gatgctagca
     5161 ttattttttc ttgaagcttt cgaagatcat acggatccgc ttgttgtgtg aaagagcgga
     5221 taaatgttgg ctggatcaac agacgtgtca aaatagccca atcgcttatt tcctgttttt
     5281 ttcttcttca tttaagtctg tgagctggat agtcatcaat aatttatctt cgccaatcat
     5341 tttctcacct ctttcaaatc tttttataat ttaattataa ccaatgataa agaaaaacta
     5401 aaactttatg tcttagaaac caatttggac gattacatga tagactaagt aaaaagaaac
     5461 aaagaggtgt ttacaatggg gttgaaattt gaacgtacag ataatttaga taaacttttc
     5521 gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt
     5581 ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga aacaaaagta agttaagctc
     5641 aaaaaaagac ttaccagcca aacttttatg aaagagtttg actggtaagt cttttttatt
     5701 ctttttatga ttcaattgct tgttcgattg ctgcccacgc ttcttctttt ccctgttttg
     5761 taacggaaga aaagagaata aacgtgtcat tgcgatcaaa atccaacgct tttttgattt
     5821 cgctctcatg cttgttccat ttaccacgag ggatcttatc tgccttagtg gcaacaacaa
     5881 ttacagggat atcataatac ttcaaaaatt gatacatctg gatatcttct tgagaaggct
     5941 tatgacgcaa atctactaaa gaaacgaccg cacgtagctg gtctctagtc gttaaatatg
     6001 tctcgatcat ctttccccat tttgctcgct cagttttgga tacttttgca tacccatatc
     6061 ccggaacatc gacaaaatgt aatgcgttct cgatcaaata aaaattcaat gtctgggtct
     6121 ttcctggctt accggaagta cgggctaaat tctttcgatc aatcaatgtg ttgataaaag
     6181 aagatttccc tacatttgat cgtcctgcca gagctatttc tggcaattgt gtatctggat
     6241 attgttttgg tgccactgca cttatgataa tttcagcttg atggactttc atggtctctc
     6301 tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg
     6361 gcagcctctt ttcatcaacc cgcttttttc tctgaatctt tatagattac tgttggctca
     6421 ccagacaatt cagctgcttc ttttgtgata atcacttttt cgatgttttc atttgaaggg
     6481 atatcaaaca tcacatccat catgatttct tcaatgatgg aacgaagtcc tcgagcaccg
     6541 gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg cttcaggttc gaattcaagt
     6601 tcggtattat ctagagaaag aagtttttga tattgtttga ctagcgcatt tttcggctca
     6661 gtcaagatcc gtaccagatc atctgttgtc aatttctcta aagctgccat aacaggtaat
     6721 cgtccgataa actcagggat caatccgaat tttagtaaat cttcaggaat gatatgctgc
     6781 atgacacttt cgtcttcaga aagtttttgg ttttgtgtac caaatccaat cgtcttttcg
     6841 cccatacgat tcttcacaat cgtttcgatg ccatcaaatg caccacctac gatgaacaat
     6901 atgttcgtcg tatcaatctg aataaattct tgatgtggat gtttacgtcc gccctgaggt
     6961 ggcacacttg caacagttcc ttctagaatt ttcagcaagg cttgttggac accttcgccg
     7021 gaaacgtcac gagtaataga tacattttcg cttttacgcg caattttatc gatctcatca
     7081 atatagatga tccctttttc tgcaagttcc acattgtaat cagcagattg aagcaattta
     7141 agcaaaatgt tttctacatc ttcccccaca taaccagctt ctgtcaaact tgtcgcatct
     7201 gcgattgcaa aaggtacatt caatgttttt gctaatgttt gtgctaaaaa tgttttacca
     7261 gaccctgtag gtccgatcaa gcagatattg cttttttgca gttcaacatc atctgtgttt
     7321 tcttgtgctt gctgattgac acgtttatag tgattgtata cggcaacagc taacgagcgt
     7381 tttgcgcgat cttgtccaat cacgtagtta ttcaatactt caagaatttc tagtggttta
     7441 gggacttcag tgaattcgcg tacagcttct tcataaaatt cttcatcaat gatttcttta
     7501 cataggtcga tacattcatt acagatgtag acccctggac cagctacgat ctttttcact
     7561 tcttcttggg ttttcccgca aaaagaacag cgtacggtct cattgctact tggattgtca
     7621 tacatggtct tcacccctta acttgcaaaa agtatgcaag aaactatcaa agactttaca
     7681 gtcttttact atcataacat agtttagtaa aaagaaaaag tgtttaacaa aggatcaact
     7741 gacctatacc tttgcatttt ttactcttaa caaaaaataa ggaactgtga caaaatcgtg
     7801 tcacagtccc ttatttcgaa taaacaattt tctagaagta gcttcttcag aaatgattta
     7861 ttacttgatt tctattcttt cgcttctgtc gctgtacctg tgatcaattc gattgctttt
     7921 ttcattgtca catcatgttc cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt
     7981 ggcatgttgt atgtttctga taattcttgg atttctgcat tgatttcttc ttctgttgct
     8041 tgaagatttt cagcagctgc aattgcttcg atcacaagat ttgttcttgt gcgcatttct
     8101 gcttcacctt cgaattgttt atgcaagtct tcttctgtag aaccagttaa ttgatagtac
     8161 atttcaggag agataccttg acgttgcatg ttgttcaaga attcgtccat tgaacgatgt
     8221 acttcatcat gaaccatcac gtgtggcaat tcaacgattt ctgcgttttc aacagccata
     8281 cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt cttttgtttc tactaattct
     8341 ttgcgatatt tttctttcaa ttcgtctaat gttgatactt cgtcatcaac atcttttgcg
     8401 aattcgtcat ctaattcagg cacttctttt gcttttactt catggattgt cactttgaag
     8461 actgcttctt ttccagcaag atcttctgct tgataatctt ctgggaaagt tacatttaca
     8521 tctagacttt cacctgattt atgaccaact aattgatctt caaaacctgg aatgaatgag
     8581 cctgaaccta attcaagtga gtaattttcg ccttttccgc catcaaacgc ttcgccatct
     8641 acaaagcctt cgaagtcgat tactactgta tcgccatttt cagctgcagc atcttctttg
     8701 ataactaatt cagcttgtgc ttcttgttca cgtttgatac gtgcatccac gtcagcatct
     8761 gttacttcac ggtcttgttt ttcaacaact agatctttat attgtcctaa ttttacttct
     8821 ggtttcactg ttacttcagc agtgattacc cagtcttgac ctttttccat gctttcaaca
     8881 tcgatttttg gttgagaaac aggatcgatg ccagcttctt tgacagcagc ttcataagct
     8941 tctggtaata cagcattcaa tgcatcttca tataaagctt cttcaccgta catacggttg
     9001 aatacttgac gagaaacttt ccctttacgg aatccaggta cgttcaagct ttttttcact
     9061 ttattaaacg cagttgttaa tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa
     9121 acaccatcat tcgtgccttt tttttcaaat gttgcagtca tttaattccc tccgagttta
     9181 gaaattcatt ttatacatca aaaacgtttc atgcatacct ttaaatagta cactaaccct
     9241 ttcaaattgt aaacatattg aatggataga atccttgttt ttcataacat ttttatcttt
     9301 ttcactgata aaatctaatg gaagaagatc atttgctgca aaattttttc tctttttttt
     9361 aaaaaatctt gtttttcatc ttctgtacct tcatacatcg tttttcctgt acacgcctct
     9421 acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg tatcatagac aggataaaca
     9481 attgcagatt gcaacgtgaa ttcttctttt aacacggaac taagcagcgc atcttcattc
     9541 ccgtaacgat ctgaaaatac acataattgc tggtaacttg cctgctgctg cggctttggc
     9601 agatcttttg gtatgacttt gactaacttt tcttcaatcg tcaaatagaa aacaggatgg
     9661 cattcgttca attgcctaag tgtctccagt aattttgccc ttgctaaaat atggacctct
     9721 ggcgatacaa taagtttact cgctgtttgg ataaactcat gataaggaag ctgttcgatc
     9781 tcatcaatag acgcaagctg acgtgcaggt tccaacgaag gaagttcctc cgatttattg
     9841 tggagtgcct tgatcttctg cctctccatt tgtccggata attcttctgc aaattggatt
     9901 ttttcaatga cccgctgctc gaaagcttca taaaaatctg tacttgctat caattttcta
     9961 gcatataaaa aatcttgtgt actgattaac aagtcaaaat aaaattcagc aaactcctca
    10021 ttttgaagat actgtttttc atgcaagagt gcttgcttca atgcttcttt tttctcgtcc
    10081 aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa agctttcttt caactcgtaa
    10141 gctcgttgaa ataattcttt tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc
    10201 actcgcatta aattctcata tttttctgga aaatcaatcg gcttcacgca gtgtcctcct
    10261 cttgctcata ttcagctcat gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa
    10321 ataactgaag caccctctaa aagctagatt ttagatctga cttttagaag gtgctttcaa
    10381 ctgttactgc tttttattgc tcatcagctg ttgacttcct ggttgaacgc tttgatcaga
    10441 ttgatcgtaa caacacttgt attagtgaaa aaatcgccca gatgttgctt tttctgatta
    10501 aagactgctg gaagataccc taacatcagc aaaggaaatt ttagaatgaa ccggcaagca
    10561 ccttctctaa ctaaaacggt tgaccagcta agttcttctt catcaaagct gatgactcga
    10621 ataccaaaga tcattttccc aatcgtttgg ccatgattga atttcgtcaa taaaataaaa
    10681 tacgctagat aaataagtaa ggctgtgaat ccgtagagac tcagataaga atctgaaaaa
    10741 ttaagccaac ctagattttt ggcaatacca agtgttaaac gcgtaatagc tccgatacac
    10801 aaaagatcga ccaagaaggc aaacattcgg ataaaaaaac ctgcatagaa atacttagga
    10861 aaatcatttg cttttggcgg ttcatttctt gtgtccgtat actttttcca tttacgttgt
    10921 ttctttttga tttcttcggg cgtcaaaggc tctctttcaa aagagctcag taccttttgg
    10981 gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct tatctttttc ttgttcctta
    11041 ttttcatttg aaagctctga catgcttact cacctccgta ataatacatt gcttttggtg
    11101 attccgctgt ccctagattc tcaagaacgg ataagatctg actagtctca gaaggcttca
    11161 atccctggaa ttctgctagt ttacttccta accatgtact agcaaaccca gatggcgtgg
    11221 aagaatattc tactagttcc gcatcttcaa gctgttgttc ctttcgtata gcttttaaag
    11281 catcttcagg aaatcccaat tcatcgacta aacctacttc ttttgcttgg acaccatcat
    11341 aaatccttcc atcagcaatt tttttgactt cttcttcaga tttattccgt ccctcgctga
    11401 cgattgctac aaaacgacta tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt
    11461 cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa cgctccgctt ttaactgttg
    11521 tatcttccac acccagtttt tctagaagtc ctgaataatt caatcctgac atgatcacac
    11581 caattgagcc ggtcactgtt tcttctgttg caaagatttt atctgcttga gcagaaatat
    11641 agtagccacc gctagctgcc atgtttttca tgctgacata cattgggata tcatgttctt
    11701 tacgaatcgt atccaatttc ttagcgattt ccgcactttc gtagacaccg ccaccaggag
    11761 aatttacttc taaaaagata cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt
    11821 ccataaaatt tttatgattg taaccttcag aagcaaataa acctgaagac cctcccgcag
    11881 caatcgttcc atctactgat aattttacga ttttttgcgt actgtctccc tcttccaaca
    11941 catttggagc tagttcttca tccccatata accaactgtt caatccctca atttgatcgt
    12001 tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa
    12061 tcagaactgc tgcccaacgt cttttattca ttctttctcc tttctaatac aagtttttta
    12121 tgacgatcac agtttctgac tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg
    12181 catacccgga aaacgactct tttgttaatt catcttctac cgtaaactca cgagcttgag
    12241 caacttccaa ggcatcaggt gcgatttctt ggatgctatc ccagccagta tctaaaaata
    12301 ttttcgtatc atctgataca ccagctgatg cttcgaattt ggacaattgt ttttttaaca
    12361 ttcccagtgt catgatctca atttttgaat ccatttttac tcctcctcta tccgattact
    12421 ttctattgta ccgaactcct gaaaaagatg atagataaaa acccattatt ttttgacata
    12481 aaaaggacat ttgacaaaga atttgatata taccaattta ttttttattc tttttttgtt
    12541 gacaagaaca ttcgcaaaag gttatgattt taaatgtttc cagataaaaa acaaaaagga
    12601 ggatagttat accttttagg atagcgccag gtctgtgtaa acagatgacg aggagagggt
    12661 ttatcgaaag attcggcgga tggccctagg gactgcactc tacagaaaat ccacaaaaaa
    12721 tgtctgcaaa gataaaacaa aaggattttc ctgcagctgg aagcattcat acgaattcat
    12781 tatagaaagt aggatgtttt ttatgtgcgg aattgttgga atgattggat taaaaaatgt
    12841 aacaccagga ttgattgacg gtctagaaaa attagaatac cgtggttatg attcagctgg
    12901 tatctttgtc tcagatggca caactgatta tctggtcaaa gcacaaggca gaattcaaaa
    12961 tttgaaaaac aaaataaata ttgatactac aggaaatata ggtattggtc atacacgatg
    13021 ggcaactcac gggcaacctt ctgaagaaaa cgcccatcca catacttccc aaagtggacg
    13081 cttcgtgctc gttcacaacg gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt
    13141 agcaaatgac cactttattg gtgagaccga tactgagatt atcgctcatc taattgaaac
    13201 tttcgcgaag gatactacaa cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg
    13261 ttcttacgct ttcgctttga ttgatcggac agcacctgat gttatttacg tcgctaaaaa
    13321 taaaagtcca ctattaatcg gactcggcga tggattcaat gtgattgcca gcgatgcaat
    13381 ggctatgctt gctcatacga aggaattcgt tgagattgaa gatgaagaga tggttaccgt
    13441 cacatcagaa aaagttatta ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt
    13501 cgaagcacaa gtagatgctt cagatatcga gaaaggtacc tatccttttt atatgctgaa
    13561 agaaatcgac gaacagccta ttatcatgcg tcgtatcgct caaaaatacg taacagaaga
    13621 caatcgtgtc tctcttgatc aaaagctggt cgatacattg tctgatagcg atcgaatcta
    13681 tatcgttgct tgcggaacta gttaccatgc ggggttagca ggtaaacaga ctttggaaaa
    13741 attgacacag attcctgttg aggttcattt agccagtgaa tttggctata acacacctct
    13801 tctttcaaaa aaaccattct ttattttctt gagtcaaagt ggcgaaacag cagacagccg
    13861 ccaagtgctg gtaaaaatca accgtctcgg ctacccttca cttacgatta caaatgttgc
    13921 tggttctact ctttcgcggg aagcatcctt tacactgcta ttgcatgctg gacccgaaat
    13981 cgcagtagca tcaacgaaag cttatactgc acaaatagct gtactaactt tattagccaa
    14041 agctatcggt gataaaaaag aatttgaaac ttctcttgta ttcgatatca ctcatgaatt
    14101 gagtttagtt gctaatgcga tggaatcggt catcgcccaa aaagattatt tagaagagtt
    14161 ggcagaagta tatctcagcg atacaagaaa tgccttttac attggacgtg gtgctgacta
    14221 caacgtttct cttgaagctg ctttgaaatt gaaagaaatc agttatatcc aggcagaagg
    14281 ttttgccgct ggcgaattga aacatggaac gattgctttg atcgaagaag gaacaccagt
    14341 gatcggaatc atcagtgaag aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt
    14401 cgaaagccgt ggcgctaaaa cactagttat tgtctcagag ggattagaaa aggaaagtga
    14461 ccagctggtg ctaccaactg tccaccctta tctaactact ctaaccacag tcgtaccgac
    14521 tcaattactt gcatattacg caacgctatt acggggattc gacgttgaca aaccacgtaa
    14581 tttagcgaaa tcagtgacag tagaataata aaagaacaag gaccagtgtc agacatctga
    14641 cactggtcct tgttctttta ttttttatga aaatatctct taatccagtc cgatttcttc
    14701 tttgactact gccgcgattt tatcgacata gtaattaact ttctcatcag taggcgcttc
    14761 tgccatcact cgaagtaatg gttctgtacc ggaaggacga actaggattc ttccttctga
    14821 tcccatttca gcttctgcct cttcaatcac ttttttgatt gccggaacat ccatcgcacc
    14881 gtttttatca cttacgcgga tattcactaa tttttgcgga tagattgtta cctctgctgc
    14941 aagctctgat aatttcttac ctgtctgttt catgatattc agtaactgaa ttcctgaaag
    15001 catcccatct ccagttgtgt taaaatctaa gaaaatcatg tgcccagact gctcgccgcc
    15061 aaagttataa tcgtttttgc gcatttcttc tacaacgtaa cgatcaccaa cttgtgtaac
    15121 gacatctttc aaaccgattc cttccaccgc tttgtggaat cctaagttac tcatgacagt
    15181 cgtaacgatc gtatcttttt tcaatcgatt tttttctgcc aagtatttag cacagataaa
    15241 catgatttta tcaccgtcga caatgtttcc aagttcatcc accgcaataa tacgatcgcc
    15301 atcgccatcg aaagctagtc cagcatctgc tcctttttca acgaccatct cagctaaacg
    15361 ttctggatgg gtagagccta cgccgtcatt gatatttaac ccgtctggat ttgtgcccat
    15421 tgtataaaaa tctgtttcaa gatcggcaaa caaacgatta acacttgttg aagttgctcc
    15481 gtttgctgca tcgacacaaa tggtcaaacc ggaaaggtca ccgttgatcg tttgtacaag
    15541 gaattgagaa tatttcaata agccttctgg aaattcttct acagttccca atccttcagc
    15601 tgatggacga ggcaattcat ccacttcagc atctaataat gcttcaattt ctagctcttg
    15661 gtcatctact agtttaaaac catctgcacc gaaaaatttg attccattat cttgtgctgg
    15721 attatgagaa gcagaaatca tgacccctgc gcttgctttt tgcaaacgtg tcagataagc
    15781 aacacctggt gtagagatca cacctagctg gaacacttcg atacccaccg ataaaagtcc
    15841 tgaaatcagc gcttcttcta acatttgacc tgagattctt gtatcccgcc ctactaacac
    15901 gcgtgggcgt tttccttctt cttcatgctg gcttaggaca taacctccgc accgtcccag
    15961 cttaaatgca agttctggcg taagttcctt gttggcttca ccgcgtacgc cgtctgttcc
    16021 aaaatattta cccatagttg taaaattact cctttaactt aattttctga ggaatttgtt
    16081 ctgctcattt gtgttgattc gcttgtttct gatgtttctt ctgtacttgt ggtcgagctg
    16141 cttgtcccag attccgaact ggaagaaatg gttgttgtcg atggttccgt tcctgaatca
    16201 gcagatgaaa tacttctact cgtacttgta ttttcttgtg tccgactgct cgtcgaagca
    16261 gagctactgc ttgacgtttg caacacgggt gtaatctcca cactaactga ttcgggcttg
    16321 atacttaacc cctcttctac tggtatttca attttacgag ttgttcgatg attgatacct
    16381 gagacattga tcggtacagc aatactgtca ccgatcgatg caagcaaatc gctagagccg
    16441 cttacttctg cttccagttt tgaaaaactg aaatcatagc tttctacccc ggcagctggt
    16501 gttccttgct gtatcccata aagtcgtacc gacttgcttg gcttgatcga atcagctctc
    16561 actgttactt gcactggatc agagacgata cttaatactt cccctgctgc attcagcgcc
    16621 tgtattggga cctcactatt aatcccatca tctgtgacca tcgaagcgtc cacatcagct
    16681 actactcgtt tgatttctgc caatgttttg tcacctgtag tgatagagac ttttttagga
    16741 ctaacggaag tatcatcaag ttcatatcca gatggtgtga acgttgaagg aatcaacgtt
    16801 tccacatcga aatcttttat tacctttttc tcaaccgtta ctgtaatagt cgatggttcg
    16861 atctttgctg tgacagcact gctcaaattt tgaattttta gcggaacttc atgtgttcct
    16921 tcgcccagct tagtgatatc tgctgtgacg cggaacatcc gtgtatcttc gtttgcctct
    16981 gcattcaact gaactcggtt tgcactggaa agtttgacag tcactgcatt ttcatatcca
    17041 tggatatagt agcgctttga atcataagaa atcttgatcg gcacccccgt aactgtttga
    17101 ttatacgctt catttccaga aagcgtattt ggaacggact ggccatttgc attgaagtac
    17161 agcgcaatac tgaacagcaa tgcaataaaa ctgtaaagaa tgcttgtccg tttctctttt
    17221 gagatcattt gcgatcccct cccttagtca taccgtctag gaaagattga atcacgtttt
    17281 tcttgttttt tgttttctct tcagcaatta gttctctacg caagattgcc aaatattctt
    17341 gctgggataa gccagccatc agttcattat ctaacgtgat gctgacgtcc ccggtttctt
    17401 cagagacaac gatggtaatc gcgtcactga cttcgcttat accgacagct gcccggtgtc
    17461 gagtcccgaa ttctttaggg atcaacatac tttctgatag aggaagatag gcgcttgcta
    17521 ctgcgatctt tccttctttt acaataactg caccgtcatg cagcggtgta ttaggaataa
    17581 agatattgat cagcagctcc ccagtgatat ctgcatctaa agcaatccct gtctcaatat
    17641 actcatctaa tccagtatga cgttcgatag tgatcaacgc accgattttt cgcttggaca
    17701 tatattggat ggctttgtca aaagacaaga tcatcttctc atcttcctgc tgttcgcttt
    17761 ttgattgttt gaaaagcgaa ctgcgtccaa gatgttccag tcctctccgg atttccggct
    17821 gaaaaatcac gatagcagct atcaccccgt acgtaatgac ttggttcatc agccaagaca
    17881 aggtgtgcag accaatgatt tccgctacga ttcggataac aataaaaata gctacacctt
    17941 tcagaagctg aatcgctttt gtgcctcgca gcagttggat cagtttgtat acaagatacc
    18001 agacaaccag aatatcaagt atgttcacca aaaaattcag agagaacaag tcaccggaaa
    18061 acatttgctg ccaatagtcc aaattaaaaa gttccccgat ttgaaatgac ataaaaagcc
    18121 tctcttctct tttgagattt cctctctagt atatcatatg ttttaatttt agaggctgat
    18181 atgctcgtat ttttcttgag aaaaacgcat aattttcaag aaaattgcaa gtatgcgttt
    18241 tatttttctc tgcaataaat atttttaaac ttcagagaat tattcattat attttttctg
    18301 ttatttttcc tttttttctt ttgtagcttg ttccattttt ttacgtcgtt ctgctctggc
    18361 agctcttcta gcagctcttc tttcttctgc ttcaaggtcc gtcgtttttt cttttctagt
    18421 cttaacgggt acatcgatag attcctctgg ttcaagtcgt ttcttgattt tttctaattc
    18481 tcccgtcagt gcagcatagt tgtaaaaacg tgttttagcg tcgtggacag tcttttcaaa
    18541 taaagctttt gcaagatttg gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct
    18601 catgaaatca ggcatagcag agaaatcagg ttttttgtag tccaaagtca ttgggttctt
    18661 gtttttttcg accattgtag ggttatatcg atataatgac caataaccag aagaaacagc
    18721 ttcttttgct tctttaagcg attctttcat tccgccaagc aagccatgtg tgatacaagg
    18781 cgtataggca ataatcagag aaggaccagg atacttttct gcttcttcaa atgccttgat
    18841 cgtttgcatt tgattggcac ctgaagcaat ttgcgccaca taaacatttc catatgtcat
    18901 cgccatcatt cctagatctt tctttgaagc atactttcca ctagccgaaa atttagcgat
    18961 tgccgaagct ggtgttgctt ttgaggtttg accgccagta ttggaataga cttcgttatc
    19021 caaaacaagg atattcacgt ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc
    19081 aatgtcgtaa gcccatccgt ctccaccaat catccattgg ctgtttttta cgaatagatc
    19141 ctttctcttg tatatatcct ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc
    19201 ttgcagtttt gctgctcttt gctgcgttcc ttcactctca aacatgtgta ctaaccagtc
    19261 ttccatcaat tctcgtagtt cttctgatac ttttggcaat acttctttga ttgaacttgc
    19321 caaagcctcg cgacgagtct gtgccgctag aagcatacca taaccaaatt cagcattatc
    19381 ttccaataaa gaatttgacc atgcaggccc ttgaccacat tcattggtcg tataaggaga
    19441 agcaggagaa gcaccgcccc aaatagaaga acagcctgtc gcattcgcga tcatcattcg
    19501 atcaccgaac atttgtgtca ataattttac ataaggtgtt tcgccacagc ctgagcaagc
    19561 gcccgagaat tcaagaagcg gttgattgaa ttgtgtagac aagacagtat tctttccttt
    19621 gactggattt gctttttgtc ttaatgtcat tgcaaaagcc caattcacag cttgttcttt
    19681 ctgttcttca taaggcttca tcactaaagc tttttctttt gcgggacaag cctctacaca
    19741 cagaccacaa cctgtacagt cttccactga aacttggata cggtatttta cgccgtctgc
    19801 gcctcgcatt tctctcacga taaatccttc tggcgcttct tccatttcct cttcatctgc
    19861 taaaaatgga cggatggcag catgaggaca aacaaaggca cattcattac acatcgtaca
    19921 gcgatcacta atccactcag gtacttctaa agcgacgccc cgcttttcca tagaagccgt
    19981 tcctaaaggc atttcgccag ttgtcattcc atttgctaca agtgtaccaa cagagagttg
    20041 atttccttcc tgtgcattca ctggttcaag tatttcttgt atataaccag tgttcctttt
    20101 attgattttt tcaggcatct ccaacgttct ccaatggtct gggatcgcga cttgatgaag
    20161 cagttcggtc gtccgatcga ttgcttgtat gtttttttct acgatagcca ttgatttatg
    20221 tccatagctt ttcagggctt cttcttttag cagcggaagc acctcatcaa aaggaatgat
    20281 gtcagctaat ttaaaaaaag ccgtttccat tgccgtattg atccggcgtc ccaaaccgac
    20341 ttcttgggcc aatctcatgg cattgatcgt atagaatcta atgttatttt cagccaagta
    20401 acgttttaat tttaagggca gatgcgtttc taattgttcg tcgctccaaa gagtattcaa
    20461 taaaaaaatg ccacctggct tcaatccttt gaccaagtca tagctatgca ggtaagctgg
    20521 tgtgtgacag gcaacaaggt ccgcatgctc gacaagatac gctgaacgta tcggcgtatc
    20581 tccaaaacga agatgagaga cagtcagacc gccagatttt ttcgaatcat aataaaaata
    20641 gccttgcgca tatttatcgg tgtgatctcc aataatcttg atagctgatt tatttgctcc
    20701 aactgttccg tcagatccaa atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa
    20761 atccagactt tcctttggtt ccaaagattg ataagtcaca tcatccacga tccctatggt
    20821 aaaccgtttt ttgcgtatgc ttgggtcttt tttcaattca tcaaaaactg ctgagatttg
    20881 gtcgggagtc acatctttag accccaatcc gtagcgacca ccaataacag ccgggcgaag
    20941 ttcagaatca tataacgcac tttgaacgtc taataagaga ggttctccac ctgcccctgg
    21001 ttctttactt cgatcaagaa cagcaattgt ttttactgta tgaggcaact tttgcacgaa
    21061 tgtttccact ggaaaaggac gataaagatg gatattcaaa aaacctgttt tccgtccgtt
    21121 tgcattcaag taatcaatcg tttgttcaat cgtctgtgca actgatccca tagaaacaat
    21181 gacttcttcc gcatcgtctg ctccgtaata agtcaccaag tcataagaag ttcctcgtaa
    21241 tcggttgatc tctttcatat atttttgaac gatttcaggt aatttatcat aataggggtt
    21301 gatcgtttcc cgttgttgaa aatggatgtc tggattctgg ttcgtaccac taacagtcgg
    21361 atgattggga ttcatccctc gtttacgaaa tgaagctaat ttctcctgat tgatcagagg
    21421 agctaattct tcatattcca aaacttcgat tttttgaatc tcgtgactcg tacggaatcc
    21481 atcaaagaaa ttcaaaaaag ggacttctcc ttcaatagaa gcaagatggg caacaggtgc
    21541 taaatccatc acttcttgta cactgctttc agctaacata gcaaatcctg tttgtcttgc
    21601 agccatcacg tctccgtgat ctccgaaaat attcaacgca tttgtcgtca ctgcccgact
    21661 agcaacgtgg aaaacacttg gcagtagttc cccagcaatc ttgtacatat tcggtatcat
    21721 caaaagcagc ccttgtgaag cggtatatgt agttgtcagt gcaccagttt tcaatgatcc
    21781 atggaccaca ccagctgctc ctgcttcgga ttgcatttct actactttta ctggttgacc
    21841 gaatacgttt tcttttcctg ctgctgacca ttgatctact aattcagcca tggtcgaact
    21901 gggtgttatt ggatatattg cagcaatctc ggtaaatgca taagaaatat atgcggctgc
    21961 cgtattgcca tccattgttt tcatttttcg catgattcat catccttgtt catattctct
    22021 cttattatct gttccattat aacgtaaaac atgccatttt tttcttttat ttataaaaat
    22081 attttacatg tatctatttg aattggtcat ctaattttta gacaaacagt ctaaatcgtt
    22141 gccttttttt gtcagacatg tataaactat aagcgaaaga ggtgttttaa catggatata
    22201 tcagtgattg atgcaacgaa aacaaataca caaaaaggaa tcctttatgg ttcatcgaat
    22261 gctcctaaaa aaatggtcga attcatcaac ttagcttgtc cgtattgccg acaatggttt
    22321 gaagaatctt atgagctatt agaagaagca gtccaaagcg ggcaattgca gcgagtgatc
    22381 aaattgttcg ataaagaaaa agaaagctta cagcgaggga acgtgatgca ccggtatctc
    22441 acaatcagcg atggccaaaa agcgatcaaa gagatcaaac aaatattcga tactcaagac
    22501 gagtggaaac atctttctct ccaagaagta gcggattttg cagtagataa actaaagctg
    22561 acagaacaaa aagacgaaca gctgagccaa gctgtcatca acgaagctga gcaagcacat
    22621 attcgatttg ttccaactgt catcttgggt aaagaaatct ttgatgaatc tatttcaata
    22681 gaggaattaa aagaattgat ccaaacaaaa taaaaaaata aggagcgtg
//
LOCUS       DAFLWZ010000042        22325 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000042 DAFLWZ010000000
VERSION     DAFLWZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.042"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            5..403
                     /locus_tag="L1V38_001734"
     CDS             5..403
                     /locus_tag="L1V38_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1316286.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1081
                     /locus_tag="L1V38_001735"
                     /pseudo
     CDS             387..1081
                     /locus_tag="L1V38_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(1675..2562)
                     /locus_tag="L1V38_001736"
     CDS             complement(1675..2562)
                     /locus_tag="L1V38_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1316287.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2747..3586
                     /locus_tag="L1V38_001737"
     CDS             2747..3586
                     /locus_tag="L1V38_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1316288.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3782..4756
                     /gene="sgrA"
                     /locus_tag="L1V38_001738"
     CDS             3782..4756
                     /gene="sgrA"
                     /locus_tag="L1V38_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBN1316289.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5054..5410
                     /locus_tag="L1V38_001739"
     CDS             5054..5410
                     /locus_tag="L1V38_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316290.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5413..6570
                     /locus_tag="L1V38_001740"
     CDS             5413..6570
                     /locus_tag="L1V38_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316291.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6596..7036)
                     /locus_tag="L1V38_001741"
     CDS             complement(6596..7036)
                     /locus_tag="L1V38_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1316292.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7196..7702
                     /locus_tag="L1V38_001742"
     CDS             7196..7702
                     /locus_tag="L1V38_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1316293.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7870..9783
                     /locus_tag="L1V38_001743"
     CDS             7870..9783
                     /locus_tag="L1V38_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1316294.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9788..10789
                     /locus_tag="L1V38_001744"
     CDS             9788..10789
                     /locus_tag="L1V38_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1316295.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10991..11197)
                     /locus_tag="L1V38_001745"
     CDS             complement(10991..11197)
                     /locus_tag="L1V38_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBN1316296.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11843..12691)
                     /locus_tag="L1V38_001746"
     CDS             complement(11843..12691)
                     /locus_tag="L1V38_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1316297.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12690..13757
                     /gene="gnd"
                     /locus_tag="L1V38_001747"
     CDS             12690..13757
                     /gene="gnd"
                     /locus_tag="L1V38_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBN1316298.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13759..14760
                     /locus_tag="L1V38_001748"
     CDS             13759..14760
                     /locus_tag="L1V38_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBN1316299.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14757..15041
                     /locus_tag="L1V38_001749"
     CDS             14757..15041
                     /locus_tag="L1V38_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBN1316300.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15074..15871
                     /locus_tag="L1V38_001750"
     CDS             15074..15871
                     /locus_tag="L1V38_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1316301.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15885..16718
                     /locus_tag="L1V38_001751"
     CDS             15885..16718
                     /locus_tag="L1V38_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1316302.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16736..17593
                     /locus_tag="L1V38_001752"
     CDS             16736..17593
                     /locus_tag="L1V38_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1316303.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17615..18124
                     /locus_tag="L1V38_001753"
     CDS             17615..18124
                     /locus_tag="L1V38_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316304.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18161..18562
                     /locus_tag="L1V38_001754"
     CDS             18161..18562
                     /locus_tag="L1V38_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316305.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18674..19027
                     /locus_tag="L1V38_001755"
     CDS             18674..19027
                     /locus_tag="L1V38_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316306.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19061..19504
                     /locus_tag="L1V38_001756"
     CDS             19061..19504
                     /locus_tag="L1V38_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1316307.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19521..20606
                     /gene="uxuA"
                     /locus_tag="L1V38_001757"
     CDS             19521..20606
                     /gene="uxuA"
                     /locus_tag="L1V38_001757"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1316308.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20599..21312
                     /locus_tag="L1V38_001758"
     CDS             20599..21312
                     /locus_tag="L1V38_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1316309.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21519..21668)
                     /locus_tag="L1V38_001759"
     CDS             complement(21519..21668)
                     /locus_tag="L1V38_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316310.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22064..22264
                     /locus_tag="L1V38_001760"
     CDS             22064..22264
                     /locus_tag="L1V38_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1316311.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7689 a         3429 c         4623 g         6584 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcagcgata acgttaggta aagagctact
      961 agatcaagta ttagagatgc cctcgattga taaagcagtg aggggcttcc aagaagattg
     1021 ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa aaggtcgctg attacttctg
     1081 aatcaatttc tccataaaat aaacgatagc cttctcgaaa actcgaggag gctatctgac
     1141 gattcaatat tcattaattt aaagtttggg tgactattac taactattac ttatttctca
     1201 tttaaacgat gtattcccta acctctaata catccttgta actctgaagt tacgccagtt
     1261 ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt tcgtgtttct
     1321 ctagtataac agaataagaa gaacaagtcc agaagggata tttttagtct tttttaaaat
     1381 aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg gcaagtgaaa
     1441 aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga tagaaataaa
     1501 aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt tttggtacaa
     1561 ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa taagaaggaa
     1621 tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat ttgtttattt
     1681 gaatatattt tttacataag gatctttaat agttacattg tcttttttca tcactttacg
     1741 gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa ttttttctag
     1801 ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca tttttactag
     1861 ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag aaacttcccc
     1921 gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat tggttgaatc
     1981 aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag cttgaacaag
     2041 cttggagaaa ttttctcctt catttgcttc tttttttgct ttatctgctt cttctttagt
     2101 cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag cagtgtctag
     2161 atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca gcatctgttt
     2221 aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt ccttgtagtt
     2281 tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg aagaaatctc
     2341 ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata gtgtttgatt
     2401 atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc cacctttaaa
     2461 cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg cacatgctga
     2521 aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct tattaaaaac
     2581 agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct gtagatattc
     2641 ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt ttcacgagac
     2701 aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga tcaggattat
     2761 tcggttgatt ggatctgttt taatagtctt tgttggtttt gttttaggaa ttcttgtcaa
     2821 taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa ttgccggtac
     2881 ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg tcgaaggaaa
     2941 aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt tagcgggagg
     3001 tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt tgacgggggc
     3061 gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt ttattttatt
     3121 tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc atcagatgct
     3181 tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc ttttgcacgg
     3241 attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag gttgcttttt
     3301 cagcgcactt atctacagta caggaagttt atttacggct attggtgctc atattacttg
     3361 gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag aacaaggttt
     3421 tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact ttggggctga
     3481 agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt tactctatgc
     3541 atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga tgaagaaagc
     3601 aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa aagtaaacaa
     3661 attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc gtgttctcat
     3721 cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga gagtgataga
     3781 aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa ttgcagcaat
     3841 gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat ttactgtgaa
     3901 aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag tcaaaccaaa
     3961 caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg atggtaatgg
     4021 aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga ccgctggtat
     4081 tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga gtaaagataa
     4141 agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt tgaaaccaag
     4201 cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg aaagcagtac
     4261 agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaatta gcacagaaaa
     4321 cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag gaagcacgag
     4381 cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca tgagtagtga
     4441 gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata atgaacttga
     4501 tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca acctaaaaag
     4561 tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa aagcgaaaga
     4621 aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga acaagctaat
     4681 tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc gttctctctt
     4741 ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa cgatagattt
     4801 ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag ctttgccaga
     4861 tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac aaatggaaaa
     4921 taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga aaaatcagta
     4981 acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata atagataaaa
     5041 aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag tatatcaatt
     5101 tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata tcgctttaga
     5161 tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat cgttttgcga
     5221 aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa aagtcgagtt
     5281 ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa cgattggtta
     5341 tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc ttagtcaaaa
     5401 aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac tattttgaaa
     5461 aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga agaataccgt
     5521 atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca ttctgatata
     5581 ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca tgcgccatat
     5641 acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt gcaacgaatg
     5701 aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt gcatccattg
     5761 ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc aaacttctgg
     5821 tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt tggtgtaatg
     5881 aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga aagttggggc
     5941 tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg ttttacaact
     6001 tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc aagggttttt
     6061 gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga ttttcagcat
     6121 atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc tcgcagaatt
     6181 ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata ctgtatgtta
     6241 gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca atcaaagtat
     6301 ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga acgcccaata
     6361 aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta tcctatcgac
     6421 aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca acctacaaaa
     6481 aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa aaatagatcc
     6541 atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc caaaattaag
     6601 acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc aagagttcgt
     6661 tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct tcgctaaatc
     6721 cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa gaaggggatg
     6781 tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga acaagatttt
     6841 tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc aattttagta
     6901 agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg ataaacggta
     6961 tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca gaacctgtat
     7021 acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa taacatgaag
     7081 aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca cgtataatgg
     7141 aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca caagtatgtc
     7201 aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt ttgattcttc
     7261 gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca aaacatacga
     7321 aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag tgccacaaac
     7381 aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt ttgtgagaaa
     7441 aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg aattggactg
     7501 tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga ctgtgaagtt
     7561 tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa cttatgataa
     7621 tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg ataaacgatt
     7681 tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa tggatactgg
     7741 tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat ttttatggga
     7801 taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct cctagaaaca
     7861 taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt ggtcatctta
     7921 tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat ttcttccgaa
     7981 tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga aacgaaatcg
     8041 agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt tactagcaca
     8101 gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac agctacaaaa
     8161 atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg gacagaaaat
     8221 gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta cttcggtaaa
     8281 cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt aatagagtta
     8341 ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat caaacatctg
     8401 attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt gatgtcgatg
     8461 cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta tccaaataca
     8521 aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga tgtatatgca
     8581 tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt tcgagggaat
     8641 tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg gtataattta
     8701 ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac ctatggacaa
     8761 tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg gccatctcaa
     8821 aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt attagcgaaa
     8881 gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc aattgatgaa
     8941 caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc cataaaaaat
     9001 cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct tttgaaacaa
     9061 tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac gattggaatg
     9121 tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt acctgtgtct
     9181 aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt agtagaagga
     9241 gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca tgtaacggac
     9301 tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga aaacaataaa
     9361 agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga aaattatatg
     9421 acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc gactgaaggg
     9481 atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc agtagctcca
     9541 ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga acctcgagag
     9601 gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca aaaaaagaca
     9661 gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct tctcatttat
     9721 tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag aaagagaggg
     9781 taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca tcgtagttat
     9841 tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct tgcttgttag
     9901 aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg atttccagca
     9961 aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt acaaaaataa
    10021 taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc ttttctggat
    10081 gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt tggaatatct
    10141 atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac cggaagcaaa
    10201 acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa aagagataaa
    10261 agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg cacaaattag
    10321 tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc atcttgatcc
    10381 gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt tggatccttc
    10441 tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat gtggatgggc
    10501 ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag ccttggtcag
    10561 acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa atacgtttac
    10621 gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag tcacaaaagt
    10681 agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt tcagcaataa
    10741 acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa gtcttatgat
    10801 gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt tcaataaaca
    10861 agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga tggcaagggg
    10921 caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc ttttacgtaa
    10981 attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat ccgaagcctg
    11041 cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt tccactaata
    11101 ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa atcaatgcac
    11161 tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc ttttttataa
    11221 ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga tgtgaataaa
    11281 atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa tgattcagca
    11341 atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa atatgggaat
    11401 ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg atgtatccta
    11461 aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca aatgataacc
    11521 taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa aatttttttt
    11581 aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa ttttttacta
    11641 ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt
    11701 ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct
    11761 tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt
    11821 tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag
    11881 cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca
    11941 aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag
    12001 aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa
    12061 taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg
    12121 attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca
    12181 tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat
    12241 gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag
    12301 attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt
    12361 catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg
    12421 ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg
    12481 ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag
    12541 agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg
    12601 gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg
    12661 ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta
    12721 tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa
    12781 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
    12841 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
    12901 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
    12961 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
    13021 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
    13081 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
    13141 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
    13201 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
    13261 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
    13321 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
    13381 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
    13441 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
    13501 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
    13561 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
    13621 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
    13681 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
    13741 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
    13801 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
    13861 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
    13921 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
    13981 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
    14041 caccagacaa tcgtatctat catacctgct ttaattgaac gaaatgctgt agcagaaaat
    14101 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
    14161 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
    14221 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
    14281 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
    14341 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
    14401 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
    14461 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
    14521 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
    14581 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
    14641 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
    14701 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
    14761 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
    14821 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
    14881 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
    14941 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
    15001 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
    15061 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
    15121 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
    15181 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
    15241 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
    15301 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
    15361 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
    15421 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
    15481 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
    15541 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
    15601 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
    15661 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
    15721 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
    15781 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
    15841 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
    15901 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
    15961 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
    16021 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
    16081 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
    16141 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
    16201 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
    16261 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
    16321 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
    16381 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
    16441 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
    16501 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
    16561 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
    16621 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
    16681 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
    16741 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
    16801 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
    16861 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
    16921 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
    16981 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
    17041 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
    17101 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
    17161 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
    17221 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
    17281 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
    17341 agttttaggg ttgtttatga tgggggtgct tgcgggaaat tatgtaaaag tagaatcttc
    17401 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
    17461 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
    17521 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
    17581 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
    17641 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
    17701 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
    17761 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
    17821 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
    17881 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
    17941 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
    18001 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
    18061 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
    18121 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
    18181 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
    18241 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
    18301 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
    18361 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
    18421 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
    18481 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
    18541 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
    18601 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
    18661 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
    18721 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
    18781 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
    18841 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
    18901 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
    18961 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
    19021 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
    19081 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
    19141 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
    19201 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
    19261 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
    19321 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
    19381 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
    19441 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
    19501 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
    19561 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
    19621 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
    19681 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
    19741 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
    19801 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
    19861 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
    19921 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
    19981 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
    20041 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
    20101 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
    20161 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
    20221 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
    20281 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
    20341 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
    20401 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
    20461 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
    20521 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
    20581 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
    20641 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
    20701 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
    20761 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
    20821 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
    20881 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
    20941 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
    21001 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
    21061 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
    21121 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
    21181 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
    21241 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
    21301 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
    21361 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
    21421 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
    21481 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
    21541 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
    21601 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
    21661 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
    21721 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
    21781 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
    21841 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
    21901 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
    21961 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
    22021 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
    22081 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
    22141 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
    22201 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
    22261 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
    22321 aaatt
//
LOCUS       DAFLWZ010000043        22175 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000043 DAFLWZ010000000
VERSION     DAFLWZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.043"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            240..2075
                     /gene="tdc"
                     /locus_tag="L1V38_001761"
     CDS             240..2075
                     /gene="tdc"
                     /locus_tag="L1V38_001761"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1316312.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2380..3858
                     /locus_tag="L1V38_001762"
     CDS             2380..3858
                     /locus_tag="L1V38_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316313.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3824..5155
                     /locus_tag="L1V38_001763"
     CDS             3824..5155
                     /locus_tag="L1V38_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316314.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5269..7821
                     /locus_tag="L1V38_001764"
     CDS             5269..7821
                     /locus_tag="L1V38_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBN1316315.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7828..9267)
                     /locus_tag="L1V38_001765"
     CDS             complement(7828..9267)
                     /locus_tag="L1V38_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316316.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9613..9975
                     /locus_tag="L1V38_001766"
     CDS             9613..9975
                     /locus_tag="L1V38_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBN1316317.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10162..11019)
                     /locus_tag="L1V38_001767"
     CDS             complement(10162..11019)
                     /locus_tag="L1V38_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1316318.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11139..12050
                     /locus_tag="L1V38_001768"
     CDS             11139..12050
                     /locus_tag="L1V38_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1316319.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12057..13708
                     /gene="mdcA"
                     /locus_tag="L1V38_001769"
                     /pseudo
     CDS             12057..13708
                     /gene="mdcA"
                     /locus_tag="L1V38_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13810..14109
                     /locus_tag="L1V38_001770"
     CDS             13810..14109
                     /locus_tag="L1V38_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBN1316320.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14099..15775
                     /gene="mdcD"
                     /locus_tag="L1V38_001771"
     CDS             14099..15775
                     /gene="mdcD"
                     /locus_tag="L1V38_001771"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBN1316321.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15779..16372
                     /locus_tag="L1V38_001772"
     CDS             15779..16372
                     /locus_tag="L1V38_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBN1316322.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16396..17472
                     /locus_tag="L1V38_001773"
     CDS             16396..17472
                     /locus_tag="L1V38_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBN1316323.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17497..18366
                     /gene="mdcB"
                     /locus_tag="L1V38_001774"
     CDS             17497..18366
                     /gene="mdcB"
                     /locus_tag="L1V38_001774"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBN1316324.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18477..19241
                     /locus_tag="L1V38_001775"
     CDS             18477..19241
                     /locus_tag="L1V38_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBN1316325.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19730..21823
                     /locus_tag="L1V38_001776"
     CDS             19730..21823
                     /locus_tag="L1V38_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1316326.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21848..22150
                     /locus_tag="L1V38_001777"
     CDS             21848..22150
                     /locus_tag="L1V38_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316327.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7179 a         3788 c         4725 g         6483 t
ORIGIN      
        1 tgtttgttcg ctttttttag gttatctatt ttagaagact gatttattga aaaattgttc
       61 gcttttttgc gttgaattat cagaaaaatc cgactttatt tatttttgtt tgtaaaaatc
      121 tacgtggatt tgatgttata aaaaaaaaat tctcattttt ggcgctatag tgaagaggtg
      181 ttacagataa acacatgtat ctgcaagaca ttgaccaaca aaatatggag ggaagaaaaa
      241 tgaaagatat ggatatcaag gccgtcttta taggcgacaa agctgaaaat ggaccagttt
      301 ataaaatgtt gttgaacaag atggtagatg aacatcttgg atggagagaa aattatattc
      361 cttcagatat gcctgcaatt agcgaaggag ataagctcac tccagattat ctagccaccc
      421 gcgaccatat gatagaggtc ttggatgaag tcagtcagcg attacgcgca ggatcgatcc
      481 catggcattc agcaggccgt tactggggac aaatgaatgc tgaaacattg atgcctgctt
      541 tattagctta caactatgcg atgctgtgga acccaaataa tgttgcattg gaatcttcta
      601 tggcaacttc gcaaatggaa gcagaagtag gacaggattt tgcttcatta ttcaatatga
      661 cagacggatg gggacacatt gcagcagatg gttctattgc taatcttgaa ggattatggt
      721 acgcccgttg catcaaatcg attcctttag ctgtcaagga agtgctgcct gaaaaagtga
      781 aaaaaatgtc tgagtgggaa cttttgaatt tatctgttga agaaattttg gaaatgaccg
      841 aaagctttac ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt agcggaaaaa
      901 atatccaaag attagggaaa tggctggtcc ctcaaacaaa acactattct tggatgaagg
      961 cgttagatat ttgcggagtc ggcttagatc agatggttgc tatcccagtt caagaggatt
     1021 atcgaatgga tattaatgct ttggaaaaaa caattcgtga attagctgga caaaaaatcc
     1081 caattctagg tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta gacagtgtag
     1141 ataaaatcgt ccaattaaga gaaaggttaa aagatgaagg gatctatttc tatttacatg
     1201 ttgatgccgc atatggcggc tatgcgcgtt cactgtttct aaacgaagca ggagaatttg
     1261 tgccgtatgc ttccttagct gaattctttg aagaacatca tgttttccac cactgcgtaa
     1321 cgattgacaa agaggtatat gaagggttca gagctatttc agaagcggat tctgtcacga
     1381 tagatcctca taagatgggc tatgtccctt atgctgctgg aggaatcgta atcaaacata
     1441 aaaatatgag aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa tcagtaaagg
     1501 ctccagatat gttaggagct tatattttgg aaggatcaaa agctggagca accgccgccg
     1561 cagtctggac agcacatcgt gtattgccat tgaatgtgac cggatatggt caattgattg
     1621 gggcttcaat cgaggcagct caaagattca gagaatttct cgatcatctg acttttactg
     1681 ttaaaggaaa aacaatcgaa gtctatccat tgaatcatcc tgattttaat atggtcaatt
     1741 gggtattcaa agaacaaggc tgtacagatt tgaacgctat caatgaatta aatgaaaaaa
     1801 tgttcgatcg gtcttcttat atggatggcg atgtttatgg tgaacggttt attacttctc
     1861 atactacatt tacacaagaa gattacggtg attctccgat tcgttttgtt gaaagaatgg
     1921 gtctaacgaa agaagaatgg aaaaaagaac agaaaatcac tctgctacgt gcggctatca
     1981 tgactcctta tttgaatgat gatcgaattt tcaattttta tacaaaaaaa atcgccaaag
     2041 caatggaaaa gaaactaaac gaaatcatcc aatagaactg atttttgtgt gaaagaataa
     2101 caagagacat atggagaaca gacaattatt tgcttcatca aaacaattgt atttccccct
     2161 gtttttcata tattcctcgc caagatattc ttttttataa aacgttctat aagttggatc
     2221 gttcgtttca tgtatcaaac ccagttcact aagatcgttc aatggatgtt tcggtgatac
     2281 tgggttttgt actgaatcga tgaaaccttg tcatttctgt tcttgaacaa aaataaaaga
     2341 aaacaaaaac atatgtcgct attgaaagaa ggaataaaga tgaaagatac tggttcatca
     2401 aagcaaatca cgaccatgac ctttatcgga atgacctgcg cccttgtagc aagtgtacga
     2461 aatattccag atgtagcagc aacgagctgg acgatgattt tttacatgct ggttgcagta
     2521 ttattgtacg cttttccaat ctcattgatc tctggtgaat ttgctggaat gtttccccaa
     2581 aaaggtggtc cagaactttg ggtatcgaat gctctaggaa aaaaatgggg gttcgttgtc
     2641 tcatggctgt tatgggtcca aatgtttcct gggatggtga tggtcgcttc agcactcgct
     2701 ccgttgtttg gtaatattat cgataatgtg ccgcttggtt tgaacagcaa atttacatta
     2761 gttgtcattt tagtcgttta ttggatcatc acttttttga atttgaaatt tgatatggca
     2821 aaaatcggcg gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac gatgatgctc
     2881 ttattagggt ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac attaggcagt
     2941 ttttcatggg acaaattaat accagatact acgactgcat cctcatttgt ttattttgcg
     3001 ccgatcatgt ttatttttac tggtatcgaa atgtcctctg tgtatatcac tcgattggaa
     3061 aatccagtta aaacgtatat tcgcggagta tttgccgcgt taatttttat atttttcgtc
     3121 aatattttga atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat ggaattgaat
     3181 aatatcgcgc aatctatttc gatttattgc caaattcttg gtttgccaca tcttattgtg
     3241 aatctgttta gtttacttgt cttcattggt gtagcagtcc aattatctgc ttgggcctca
     3301 ggaccagcaa agacagtgac agaaagtgct agaaaaggtg cgtatccacc aaaattcaat
     3361 ttttggaaga cgaatcaatt tgacgtatcc aaatccgtta ttttgactca gtctgtcatt
     3421 atctcaatct ttgcactttt ttatttgctg attcctggcg tcaatcaagc atttttgatg
     3481 ctcgtaaatt caactactgt tatctactgt atcgtctatg tcatcatggg gatcgcagtt
     3541 ttgagattgc gttatacaca tgcaaagttg aatcgaccat ttagaattgg aaaaaaagag
     3601 aaaaagagca atcttggagt ttggactgtc gttattgttt tatttgcggc aatcggattt
     3661 tctgtcggac tgacgatgaa agctggaaca tggatcaatc taattgcagt cacagccatc
     3721 agtgtcattt tgtttgtagt accactctgt attgaaaaaa taaagaaacc ttcttgggaa
     3781 caggaagtcg ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa aaccggcaat
     3841 gaaacggact ctaactaatc gaaatatcca gttaatcgca ttaggtggcg caattggaac
     3901 aggattattt ttaggttcag caaaggcaat tgcatcagca gggccagctg ttattctcgt
     3961 ttatttgata tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg atttattttt
     4021 agcaaatagt acatttaact ctatcagtga tttcgttgac tattatttag gcaaaaagtg
     4081 ggcatttttt gtcaattgga cttattggct ttgctggctt ggagctggac ttgcggaatt
     4141 aacagcaata ggattgtata tccatttctg gtttgtacat gtaccagctt tgataagcgg
     4201 aggtagcgca ctaatgatct taatggcagt caaccttgtt gcagtcaagt ggtttggtga
     4261 attggaatct tttttctcaa tcatcaagat cttggggatt ttccttttta tcttattggg
     4321 tataggattg agtgtctcag attttcatac ccagtctatc ggaatcaaag aaaattttgg
     4381 acagatcgat gaattactac cgtttggctt tgctggaatg gtagtctcat ttcctatggt
     4441 tttattcagt tttgctggaa ttgaaatgat cggcttaacc gttggcgaga caagtgatcc
     4501 gcaaaagaat ttgaaaaaag caatcaactg tctgccttgg cgtattctct ttttctatat
     4561 aggaacgatt ttgtcgattt tatttgttgt tccatggcat tgtttagatt taaaagaaag
     4621 tcctttagtg actatgctgc aagtgatcca ttgccaaggc ggagcagcaa ttgtcaatct
     4681 aatgattttg gttgcttctt tgtcctcagc aaatagtgca gtctacagta ctagcaggat
     4741 tttatatcaa acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc tttctaagaa
     4801 aggcgtacct ttacacggta ttttaattac aggaatgtta ttttttgccg gtctttgtct
     4861 acattttttt gtagctgata gtcgattgtt ttttcagctt ttggcaggca tgacaacgag
     4921 ttgttttcta tttgtgtggt cttcgatctt gtgtgcacat gttcaattta ttaaagaaaa
     4981 gaaacggaac actacacaaa gatataaaga tcttgctttg ttggtgtttt ttacttcaat
     5041 tgctttcagc ttgttattcg aaagcacgac acgctttatt ccttttttat tggttatctg
     5101 gtttgtattc ttaaattttg tatataaaag aataagcaat agaaatatca gttaggccca
     5161 gatacatttt gcaaaacgaa ttatttcaga cccccctgaa ataatcgata cgcctgaaaa
     5221 aacttccctg cgtataataa cagtatcaat taaacaggag gggataggat gaactggtac
     5281 agattgacgg tagaagatgt attgaaaaac tatcaaacat caacagaagg cttgtcgcaa
     5341 gaagaacgac agaaacgcct gactgatcaa ggatataatg aaataaaagc aaggcagcag
     5401 acaaaacgat ggaaaaaaat agcaaagcat tttactgatc tgctgatgat cgtgttgatc
     5461 attgcctctt ttttgaaatt tgcttctagt gaatatattg aaggaagtat tattttattc
     5521 gtagtgatcg tcaatggact cgttagttac tggcaagaaa gaaaagcgga agaatcattg
     5581 aatggtttga agcagctgat gggacaagaa gcgatagtac tatcaaacgg gatgcaagaa
     5641 aaaatccctg cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc cggagatgtc
     5701 gttccagcag atatccgatt aatcgaagca catgatttat tagtggaaga atcgattttg
     5761 acgggagaat cagaagcatc tgaaaaaagt catgccgttt tgacagaaga agaatcgatc
     5821 ggcgaccaga aaaatatggg tttttcagga acgcttgtac aatctggttc tgcagtcggt
     5881 gtcgttgtag aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc attgcaatcg
     5941 gtcgaacaac aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa acaaattttt
     6001 caaggcattc tttgtttgag cctattctta gttattttta cgacatttcg atatggtatg
     6061 gattggcata tccttctttc ggctacgatt gctttggtgg tgtcaatggt acccgaagga
     6121 ttgccagctg ttttgaccat gattctatcc gttggagtac atgaaatggc aaaagaaaag
     6181 gcgatcatca aaggacttcc ttcggtagaa acattaggtt ctatgacagt gatctgttca
     6241 gataagacag gaacattgac aaaaaatgaa atgacagttg tggatgtagc tgcaaaagaa
     6301 gaagcctgcg tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa agaagaacag
     6361 aaaacagaaa atttaagtgg caatccgaca gaagttgcgc tgattcgaca cacagaaaca
     6421 gccaatctac ctttgaaaaa aatagaagca aagattccgt tcagttctga atacaaatat
     6481 atggcaacga tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg tgcaccagaa
     6541 gtattatttg ctaaatcaac tctttcttct gcagaacaag aagcatggag tcagacagct
     6601 gcagaatttg cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa agtagattcg
     6661 aaacaggaac tcacgcatga gactttaacc caattaactt ttgcagggat cgccggattg
     6721 atcgatccgc caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca agcagggatc
     6781 tcagtgaaaa tgattacagg ggatcacaaa gacacagcaa aagcgattgc ggaacaaatt
     6841 ggcttaaaac atactgccaa agttttagaa gggatcgatt tggatcttat gtctgatgaa
     6901 gagttgattc agcaagtgcc aatagtcgat gtctttgctc gaacgacacc agaacataaa
     6961 ctgcgaattg ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac cggagacggc
     7021 gtaaatgatg cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg aatcaaaggt
     7081 agtgaagtaa gcaaacaggc agctgatatg gttttaggag atgataattt ccatacgatt
     7141 gcaaaagccg taaaagaggg ccggcggatt ttggataatt tgcaaaaaac catcaatttc
     7201 ttcttgccaa ctgcattagc tcaaggattg atcttgattt gggcacttat gctgaatcgc
     7261 ccgctacctt tgtccccagt acagatttta tgggtcaata tggtaacgac aatcacttta
     7321 tcttatgcac tagggttcga gtcgccagat ccagaaatca tgaagcgccc accaagagat
     7381 ccaaagcaag gaatcctatc tggttatcat ttgtttcgga tcatctatgt ctccctactg
     7441 atcatggttc ctgcctattt attggctatg cagtttgaag ggcaaagctt acagcaaacc
     7501 attcttctgc aaaatatcgt cttagctcaa gctgtttaca tgatcaattg cagagagttg
     7561 tccaagccgt cattgaacca aggtcttttg caaaacaaag cgctttttct ttcattaggt
     7621 atccttgctt tattgcaagg gatggttatt tttctaccag tcggccagca gctgatcggt
     7681 acagtaagtt taacgatgac acaacagtta ttgattggag caaatgtgat tcttctattc
     7741 ttagttgtag aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa agaaaaaaca
     7801 gctagagaat acagtcgcta gccgttacta taaaaaagtt ttgaaagtga gttcagtcaa
     7861 acgattgagc tcatttttcg ttggaataga agaaatgtat acaataggga tatctagaga
     7921 atctagaggg aaattggaaa tcaagatatc tgttttttca aaagaaatag tggaaagatc
     7981 ggttagttcg ataggtaaga agcagacacg ttttcctaag taatctttta attcctgctg
     8041 caagaacgcc ttccatgaag gttctccttg gaaaataaaa tagacattga acaaattcgg
     8101 tttgatagaa aaaatcgttt gttggatcag tagagacaag agttggagaa agtaatttgg
     8161 ttcattgatt tctatttctt tttttagatc gttcagtaaa ttctctttct gttgatacaa
     8221 gtgtgcatat tgctgatcat atgtttctaa aaaacgatgg tattgacggt ccaatgcttc
     8281 aatcaatatc ggcgattcat gatattttaa tatgaggaga gccaagttat cagtcagaga
     8341 tgtttttttt agttgatcaa gagacagctc tgaagctagt tcctctacaa acgtttcgag
     8401 gacctctaaa aatggagaat gatgcaggca gcgagcggtt tcttgtccat agttattgtt
     8461 gtaattccaa ctttccagaa agcagaaaga agcaaaagaa agctcagtgt ctttaagata
     8521 aataccttcc gttaaataca attttttcaa tgcagagtca tacagggagg agagtgtgct
     8581 gttggtatgg atagaagaat ctaatcggca attcgctttt atacggatcg tattgataaa
     8641 gaaccaacat gttccgaaaa tctcttctgt ttcaaccgct agttcagttt gactgaggtt
     8701 tcttaaaaat tgaaaataat gggattcatg gatcgaataa tcctcgaaaa aatagttgtt
     8761 atgagtgaaa ggaatcagca atcgatgata aaaagtacga atcgcacgct cttttccaag
     8821 aatacaagct gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta aacgctgatt
     8881 gattttagtc acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg ctagaaaatc
     8941 agggacagca actttttttg taaaaagcag atttttcagc agttcgacac tgactgattg
     9001 tttgaaaaaa atctcccaaa ggtcatttgt taataaattt tgctggtttt gcaaactgat
     9061 tcctgcttga tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa tagattgaag
     9121 gtcagaaaaa atcgttcgtt cggttgtccc tatgatttca gctaattcat ttacggttat
     9181 ctttgtatga ttcagcaatt gttctactaa agaaacatga cgtcgaatat ctttttcggt
     9241 aatgattttt ttcattagtg aatacatcaa tcagactccc ttctattcta agaatacgga
     9301 gaaaataaac ggtggtcaag tttcaactga tttttcaatc attgtttatt tttctggagc
     9361 atttactgat gataagaatt tcatcatgaa cttgaaaaat gataccacta aaatcaaaaa
     9421 ataggtgggc aaacaataat aaacatttta atagtagatg gtagcaagac caacacaggc
     9481 ggattgaaca tttaagagtt gataaaaaag aaaaatatcg aagtatttga ttagcaacta
     9541 cttgtattca tttttctatt cttacgtggt atctttgaat aaagcgaatc aataagaaag
     9601 agatggaagc agatgctaac gaaaaaagaa ctaatcgatc acatcaatga aacatacaat
     9661 ttgtctccag aatatatttt taaaaaattt cctgattatt gcgtattcag acatcaaaaa
     9721 agcaaaaaat ggtttggggt cctgatgtct gttccagaag aaaaaatcta tgatgatgca
     9781 agtgaccata ggatcatcaa tattcttgat ttgaaggtcg atcctgaact tggcggaatt
     9841 ttgcgaggaa aagaggggta ttttccagcc tatcacatga ataaagaaca ttggatctct
     9901 attgatctac gtaaaataga aaagctagat gaactagcag atttgattga tggaagtttt
     9961 aaatcaacgc aatgaatgtc taggacaata gagaagaggt tgtgacagaa atgtttagct
    10021 tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa atttcggctt
    10081 attttctaag aaattacttc tggaacaccg tttgttcgaa aaaagagctg cgacaagaat
    10141 tttgtcccag ctcttttttt tttattttcc taaataaaat tcccgcatcg tttttgcaat
    10201 cattttgatc aaaggatgat cttctgtgaa gctagaagat aaataaattg ttcgtgtcaa
    10261 gggcaaatct ttgatttccc gcaagacgaa aggatcattt ttatcgtaag accaagaaac
    10321 ttttgggaaa aagctaacag ctaatccttg cttgacaata gaacgtaatg tcgcaggatc
    10381 atctgtcgtc gaactgatcg tcaattcgat acttttcgct tcaagtgctg catccagtgt
    10441 atgacggaag gcgttgctct ttgacagcat caagatgggg gtgcgttgga tatcttctaa
    10501 ttgcagatgt tcttttttag caagaggatg tttcttagga atggcgacat aaacaggttc
    10561 tttcatgata ggaatattgg tcatgccagg cttcatctcc gaagtgatgt acagtacagg
    10621 atcggtaata tcatctggta aatgatgttg catgatcgtt aattggatat caggatgctt
    10681 ttccataaaa attcggacca agttcggaat agaaacagag gctacctcta aatacaatat
    10741 gacggaagta acgatcttct cattgaccga agacaataat ttgattcctt cttctaatgt
    10801 gtctaatgtc ttgactgcat atggataaaa ttcttctgca taaacggtcg tctcaatgtt
    10861 tctgccgcta tggtaaaaca aagggacacc taattcgttt tccaaatgtt tgatcgcacg
    10921 gctcaaggca ggttgagaaa taaataattc tttggctgct tgggtaacat tttttgtttc
    10981 gaatactttt ttaaaatact gcagatgaag caatttcata attatccatc ccatccatac
    11041 ctttttgtta tggttttttc tttttttggc attttttatt atagcagaaa ttgactaaga
    11101 tagcagtgga aaaagtaagt gctgaggagg cgaggctcat gagtacaggt ttcttatttc
    11161 ctggacaagg cagtcagaag ttagggatgt tagcggatat ccctgaaatg tacatggaac
    11221 gtttagaaaa tgtgacgggg tatcggttag ttgataaaga agaaaactat caagatacgg
    11281 tttttatcca gctagcatta ctgacaaaag cagtatttta tttagatgaa atggaaaaaa
    11341 acggtattca gcctgatatt gcagcaggac attcgattgg tgctttttgt gcagctgttg
    11401 cttgtcgatc tttgagattt gagaatgcag cggaactagt ctatcaccgc gcagtcttaa
    11461 tgaaagaagc ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg acgagaagcg
    11521 aagctgagga aattgtagca aaaacatttg atcctgacca tccagtttat ctgtcaaatg
    11581 aaaattgtcc gatgcaacat acgttatctg ggagtatcga aggtttatcc gttacgttgg
    11641 cagaagccaa acggcaccaa gcgcaaacag cgaagctgct gaaagtccct gtgccatctc
    11701 actgtctctt gatgaatgat acggtcaaga aattcaagcc gtatatgcag tctgtccatc
    11761 tatctgatgc tagatgtttg tatataaaaa atacggatgg aagagccact caggacgcag
    11821 aagagattcg taaagatttg ttggaaaacc tagctttccc tgtgcagtgg aaccaaatga
    11881 tggacttggc aaaagaatta ggaatggatc tgacgattga atttcccccc ggcaatactt
    11941 tgacaaagct gattcataca aaatttggtg tagataaagg gatccgtacg atcaatctag
    12001 accaacatgg tattgatgac gccacgtttc tatatcaaaa atggagatga ctaattatgg
    12061 aaaaaccaaa ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga ttggaaaaaa
    12121 tcagcaactt gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa gtaatggaaa
    12181 aactgattgc tcccggcgac aaagttgtat tagaaggcga caatcaaaaa caagcaagtt
    12241 ttctttcaga aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg catttgatca
    12301 tgtctagtat ctcacgacca gaacatttga atatttttga aaaaggaatc gcaagcaaga
    12361 tcgatttctc ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt gaagacggca
    12421 caatgaaatt aggtgatatc catacttatt tggaacttta tggacgctta ttcatcgatt
    12481 tgattccaaa tgttgtttta gtagctgcag ataaagcaga taaagacggc aacttgtaca
    12541 caggtttcaa tacggaagaa acaccaacaa tcatcgaagc tgcagctttc aaagatggta
    12601 tcgtgatcgt tcaagttaac gaagttgtcg attctttacc acgtgtagat atccctggtg
    12661 actgggtaga cgttgtcgtg aaagcagata aaccttatca attagaagct ttattcacac
    12721 gagatcctca aaacatcaca gaattgcaaa ttctaatggc aatgatggca atcaaaggaa
    12781 tctacgcaga acacggcgta caatctttga atcacggtat tggattcaat acagcagcta
    12841 tcgaattgtt actgccaact tatggtgaat cactagggtt aaaagggaaa atcgcgaaga
    12901 actgggtatt gaacccacat ccaacgatga ttccagccat cgaatcaggt tgggttgaaa
    12961 gcatccatag ttttggtggc gaagttggta tggaaaaata tattgctgct cgcccagatg
    13021 tcttttttgt cggtaaagac ggcacgatgc gcagtaaccg aacattatca caagctgcag
    13081 gacaatatgc catcgatatg tttatcggtt caaccttgca attagattac gaaggaaact
    13141 cttctaccgt aacaaaagga cgtttatctg gttttggcgg tgcgcctaac atgggacata
    13201 atcctggcgg tcgtcgtcat tctacaccag catggcaatc acttcgcgac aatgatgatc
    13261 cattagggaa aggccaaaaa ttagttgttc aaatggttga aacatatggt tcaaataaaa
    13321 aaccagtctt tgtcgaagaa ttagatgcac tagctgttca aaaacaagca ggcttagcca
    13381 atgcaatgca ccagtgatga tttatagcga agatactaca catatcgtga cagaagaagg
    13441 aattgcttat ttgtacaaag caaaaacaaa agaagaacga caagcagcaa ttgcagcaat
    13501 tggcggtgtt acacctcttg gaatgactag cacgaaagaa tcactagata gcttgcgtgc
    13561 agccggcatc gtgaaattac cagaagatct aggcatcaaa cgtagtgaag cgaaacgttc
    13621 attattagct gcacaaacca tcgatgattt gatcgaatgg tcagatggcc tgtatgaacc
    13681 accaatgaaa ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg tcgccattta
    13741 cccagatgga agaagaaaga cgaataagca gaacgtgtat gctctgtttt acaaaaaggg
    13801 gagagatcca tggaacaatt agcttataaa tatccaacga aacagccgat caataagaaa
    13861 atccatgtag gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc aacagaaaaa
    13921 acagaatcta ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt atggaacaat
    13981 gtattaacga gattttttga tcgttatcca atttcagcag atatcgtgat caatgacttc
    14041 ggtgctacac caggagttgt gtacctacga ttgacgcaag caatggagga actttcagat
    14101 gaaaaatagt tttgtagaat taaacgccag agaacgagtg aacgctctac ttgacaatgg
    14161 acgtgaattg attgatccat tcgatcaaat catcgcgcca agtttaccag cacaaggaat
    14221 cgtccctgaa agtgatgacg ggatcgttgt cagccgtggc acgatcaatg gcaaacaagc
    14281 agtagtaatc gctatggaag gaaaattcca aggtggcggt atcggtgaag tttccggtgc
    14341 aaaaatcgtt gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa atgagatctt
    14401 tccagtcatt gtactagata caggtggtgt tcgtttgcaa gaagcaaact acggactgtt
    14461 atctatttca gaaatcggaa atgtaatcat tgctctaaaa caatatgtac cagtcatcgg
    14521 tttgattcca ggacgtgtag gatcatttgg cggtatgtcg attacttcag cattaatgag
    14581 ttatttaatc gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag ttattgaaca
    14641 agaagcaggc gttcgagaat ttgattctag tgacaaagac ttgatttgga atacattagg
    14701 atctcgtcaa cgggtagaat caaaaatcat tgatgaatta gtgactgata gtgtagaagc
    14761 aatcaaagct gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc gcagtgaaag
    14821 ctcagcattt tatttatcat tacttgattc tttagatctt tcaaaaccaa tggccattga
    14881 cgattacaat gaagcaattg ctaaccatca agcaaaatca attgacttac cagaagtagc
    14941 agaaggaaat gaaccagctg cagcaagtgt tggttacgat tggtttgcgg cactaactgg
    15001 catgaaaaat ccaacttctt ctattagtac tgtgtattat ggtaaatcaa gtaaattcat
    15061 agaagaagcc atcgtgacat caatcgtacc tgatcctaaa aacccgatgt accgtgtacg
    15121 aaacggtgaa gttggtttag ttgaaggttt ccgcatggga caaattttgg atcacgttta
    15181 cgaagaagat aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg atgtaccaag
    15241 ccaagcatac ggctataacg aagaattgat cggtatccat gtggctttgg ctaatagtgc
    15301 tgctgcttat gcaaaactcc gtcaagctgg acatccagtt attggattga ttgcaggaaa
    15361 tgctatttca ggtgcatttt tagcacatgg attacaatca agccgcttga ttgctttaaa
    15421 caataaagaa attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg tgacaaaacg
    15481 ttcggttgct gaaatcgaag cagctgctga aaaagttcca gctatcgctt acgatatcaa
    15541 taattataca aaactaggag cgatctatca tttcctagaa gatatcaccg accaagctgc
    15601 ttcagaacaa aatgtcagca aagtcatcga agcaatcaat gaagccattc aagatgtccg
    15661 caatacaaat gacacgatgc tgacaaatcg atacacaaac gaaacagcca aaacattcgg
    15721 acgtgtcgaa acaaataaag tccgtgccaa aatggacgaa gaatgggatg cataaaaaat
    15781 gattcaagca catgatattg tcctttttga taaacatgaa atagaagggt tcaccttgcc
    15841 tgaatgggtc gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt cgacggatca
    15901 cgcagaaata ctaccgattg gtttacgtgg acctgcccgc aatcagagat ggtcaacaga
    15961 aatctcaaaa catgccgtca aacaagtcat tcatccgtgg gacatcatcg aacaagaatc
    16021 gtatagacaa gagaaaatca tggattatcc tgtttatcag caatttcatg ctgctagaaa
    16081 catattatca ggatgtaaat ggggaatcgg cggcagctta ggatttgaat tatcgactgg
    16141 gattccggca gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa attcaccgat
    16201 tgaattgcca attcaggtaa ttcaatcgca tcctgctttt tttgagcaat tcgataccca
    16261 agtagtgact cggcaaggcg gtttttcact aaaagagtat ttgagagagc cagagaaaaa
    16321 aattctattg aaaacagtcg aaggacctaa attaaccaaa gaactttggt aataaagaaa
    16381 aagagagaga aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag tgacttccag
    16441 aaagtatcag ctgtaacggc tgttatgatg caaacgatat tgagctttgc tttggcaaac
    16501 agccacagcg caacaaatac agcttttctt ggtacctttt acgtcatcgt taaatacaca
    16561 gcaccaatgt ttatttttgc aattgtttat aatatggtaa aaacaagtca gcatttgtct
    16621 tattgggaat ttttgaaaga aaagtttttt gaactagtcg ttccgtatct tctatggacg
    16681 acggcttatc tttggctatt tccagcagtc caacaacaaa ctccgtatac ggatactgca
    16741 agctttttac tgaaatatgt cacaggtgat ggagcgcctc atttatggta taccgttatg
    16801 atgctgcaga tccaattgtt catgccgttt tttgtttggc tcggttacaa agtatttgct
    16861 aataaaaaat atgtatggcc agtattgatt ggttcaacga ttttatatgt cgcatggtat
    16921 ctgttctatc aaacacaagt attgactggg ccttatcatg acagctggta cttattagat
    16981 cggtttgttg ctagtttcat gatttatggg gtagccgcat ttgtttatca cgaaaaagtc
    17041 tatcaatatt tggacagagt acgttatctt ttcttacctg ttgccttagt tatcgcgttc
    17101 ttttctgtcc gttcattgct cgcacatcca ggagacttga gctttgcgaa tgcaccttac
    17161 ttgaatacga tccaaagttt atacagttta gtcatcatct ttgctgtctt cataggcgct
    17221 tccaaaatga ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt gtctgtttat
    17281 gcttatcgta cgtatttagc caatgtattt gttttccaag tactgttatt attgtttaaa
    17341 gatagttggc tgcagttacc ttcaggagtc atgattcttg tagcttatct aatgacggca
    17401 agttgtgcat ttgctttaag ctggttactt catatcattt gggtagctat caaaaaaggt
    17461 ttcagcaagt aatagtagga agaaggagtg agtgtcatga taaatgacga acgaaaaaaa
    17521 gcagtgactc agcaactcgc tgcgttggta gaggaagcat tgatcgcaga agtaacatta
    17581 agtccaaaac ctggattagt ggatgcactg gatgcgggtg cacattccga tatggactat
    17641 gctttatttc ttaagtctgc taagacgcta actccttttt ttgaagaaat ggctcaaata
    17701 gcatggcatc atgctattga tcaggagtta agagaaagaa ttgctgagat tgggcgaaaa
    17761 gcggaaaagg caatgctgat tgctacaaat ggcatcaata cccataaagg agcgatttgg
    17821 gcaatggggc tattgatcag tgtcattgca caaaaaatca gtatggaaca gcctttttct
    17881 ttatcgaaaa tacttgatga tgtcagcaag cttgctgctt ttcctgatac aaaatatcgt
    17941 cataaaaaaa ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa tggtgcatat
    18001 gaagaagcga tattagggta tccgcatatc aggcttgcaa ttcaagcagc taaggagcta
    18061 gataatgatt catatgtaca gaaacaaatg catatgttgt tagttttgat gagttcgcta
    18121 gatgacacat gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat gcaaaaactt
    18181 gctcatgctg ctagtcaaag tgctttacca aatcgtccat ttacagcact gttgcacttt
    18241 tgtcaggaaa accaaatctc tcctggagga agcgcagatc tcttgtctgc aagcttgttc
    18301 atgctgaaga tagaggaatt atggactgcc gacacataca tttgtccgat gttactcaat
    18361 gactaaataa gacaaaattg ctaaaaaaac agtttatgca tctggttatt gactcttcct
    18421 tttagcaagg ctatcataaa aatagttttt tgtaataaaa gataacgagg aagacaatga
    18481 aaaaaatcaa ttatttagca atcattttgt tagtgggcct atgtttgttt gctctgccga
    18541 cccaaggatt cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt cgaagttcgg
    18601 gcagaggttc atttggtggt cgttcatatg ggggcagtta ttttggcagt cgttcttacg
    18661 gcagagattc ttatgggtat tatggtccag gtacaggtcc ttctagttat gagcaaacgg
    18721 gatttcttgc attagctgtt ttgtcagtag gaggggtttc tgctttttct atcgtcaaga
    18781 ataaaagaca aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca ggaacggcta
    18841 aagaaaagaa agcacagttt ctggaaatcc aaaagatatt catgaagatc caatccgctt
    18901 gggaagaaga aactcctgaa aaagccagaa gctgttatac agacaagctg tttgccgaac
    18961 atcagaaagt tctgcaaaaa aacaaagcag acggtgtaag aaatcatact aaaaaaataa
    19021 ctattcagga agtaggaaat tatcgacaga tccacgaaaa tagttttgcc atccgaattg
    19081 atttcagatg ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc tcaggaagta
    19141 agacacaacg acagtatttt tctcagatat ggtattttga tttttctgag aaagaaaaaa
    19201 gatggcaagc cgattttatt cagccgatta tgctggattg acaggaaata tttatgaacg
    19261 gagttgtgac aaaagccttg tcgcagctcc tttttctgaa taaacggtgt gccagagata
    19321 gcctatcggc aataaggcac gattttgtaa aatatgggaa gcgatttttc aaaatcgctt
    19381 cttatcgctc aaggctgaac atctctgtca caacctctcc actaaatggt gtttaaaagc
    19441 ttgcatctgc gataataaga acaaccaaac gaaaaatagg aagcactatt ttagtttagt
    19501 tgttcttatt acttgatgca ggacagcttt ttcacaacct cttttttgta tagatgggca
    19561 aaatttttgt aataataggc gtatgtcttt ttcgttgagg agatgaaaaa gcatatggct
    19621 tattttttgt ttgctttgct tactttcttt ccacttcaag tggcagaaat atctactttt
    19681 tattatgtaa gcggaaccat atacttgaaa tcagaaggag atcatttcta tgaaaacaag
    19741 aacaattgaa atacttcaca gaatcatgac agcccaatat ccagtaaaag caaaacatct
    19801 agcaagtgag ttcaatgtca gtcagcggac gatccgtcag gaagttcttg aagcgaatat
    19861 ctggttgagc agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag gttttttgtt
    19921 gaagctggaa aaggaaaagc aagctcgatt agaaactgaa ataaaagatg tgaaagacgg
    19981 ctttttgaat cggcgcgaac gtatttttga tctagtttta gccgttgctt acagccgaat
    20041 cccgatccat ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta cattagatga
    20101 agatatgaga cggttacgag caacactggt cagttatggg atagagatcg tcagttatgg
    20161 aaagcaagga ctggtttata aaggttcaga acgatctatc cgtacgatga tctatgattt
    20221 tatcaatcag aatctgggaa tgaccgactt ctttatgaat caagatgcac aattaacacc
    20281 ggctcaaaaa atctttctcc attattttcc tttggtggaa atcaaaaaaa tacaggagat
    20341 ctattccaat aagttgttga aacaagaaga tgatatttat aaaaaacaaa tcctgctttt
    20401 tacattgatc tggatccagc gaatcaggaa acatgaattt atctctgcca ttaattggaa
    20461 aaatacagaa ataaaagaca gtagcttttc tgcatttatt gaccacatga tcgaggaatt
    20521 tcaattggac aatgtcccgc aagtagaaag aaattatctt cgtttcacta ttgagacgtt
    20581 caatgctaga gatatctcca attcaatcga gtgggtacaa gctcaattac taacgatcca
    20641 attgatccaa tttgtagaga acgagacaca cgtacctttc catctaaagg aagaagcttt
    20701 attcgaaaat ctctataagc acatggctgc actgattgta agaatcaaga atcatatcca
    20761 agtcatgaat ccattgaaag aaaacatccg aacaaattat ttcccaatct accgcgcagt
    20821 cactcatttt gttcctacga tcgaagaagt aattggtggc aagatactgg aggacgagat
    20881 agcttttctt gtcatccact tttcgacgat cgccagtgta atcaagcgag acttgaatta
    20941 tgtttataaa tcagtcgttg tctgtaacca tgggatggct actggaaatc tgttagcaga
    21001 gaatctgaaa gaaaagtttc ctcagatcga gattactgca gttttaagtt caaaagaaat
    21061 cgaattagta gataaattgg atgtcaatct ggttttcagc acctttcaat tgaattatcg
    21121 aaataagccg cttttagttg tcgatccgat tttaactgag acgaatatct tggttataga
    21181 agactttttg aaaagaaatg aagaactaca gcggttagag cctaacagtc atgaatcgac
    21241 ggagttattc actcaaataa tagatgtcat gaaagaaagt ggtggccgag tagatcgaat
    21301 catctatggc aagttagaaa aattattcga aacaaacaat ttagaaatca acaaaaggga
    21361 gatccagcct atgttaaaag atattttgac ggacagcaat atcatgatca aagaaaaagc
    21421 cactacttgg gaggaatcga ttgaactagc tgctagacca ttggttaaag aaaacattgt
    21481 cgaagagcgc tatgtcgaag cgatgattcg tgcagtgaat gattacggac cgtatatcgt
    21541 gattggcaaa cacatggcac tagcccatgc ccgaccagaa gatggggtca ataaattagg
    21601 agtcagcgta gctacgattg agcaaccaat cgatttcggt aatcctgaaa tggatccagt
    21661 aaagattatt ttttgtttgg cagcagtaga ctcctactcg catctgaaca tcatgaaaga
    21721 actaattgaa ttgatcaaca acgaagagaa gttggatcga ttgattgaat gcacaaatat
    21781 cgaagatttc aaacaactgc ttttttcagt agttgagaaa taataaatga tacgggggag
    21841 aacaaagatg aacaaattga acattttatt cgtatgcggt gcaggtttag gaagtagttt
    21901 tgcagcacag atgtctgctg aggatgtttt gaacaaatta ggagtagaag ccaaactgga
    21961 ccattgtgat atttcttccg cagtttccat gaaaccagat gtgatcatca cagcagaaaa
    22021 ttttcgttcg cagttcgaaa agttcgcagt tgatcctaaa acggcgatga tctatttgaa
    22081 aaatattgtt tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc aagataaggg
    22141 agttatctaa atacaaaaag aaaagagggt aaaaa
//
LOCUS       DAFLWZ010000044        22023 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000044 DAFLWZ010000000
VERSION     DAFLWZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.044"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="L1V38_001778"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="L1V38_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBN1316328.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="L1V38_001779"
     CDS             complement(2017..2919)
                     /locus_tag="L1V38_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1316329.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="L1V38_001780"
     CDS             complement(2916..3608)
                     /locus_tag="L1V38_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBN1316330.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="L1V38_001781"
     CDS             complement(3651..4292)
                     /locus_tag="L1V38_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1316331.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="L1V38_001782"
     CDS             complement(4330..4644)
                     /locus_tag="L1V38_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316332.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5984)
                     /locus_tag="L1V38_001783"
                     /pseudo
     CDS             complement(4632..5984)
                     /locus_tag="L1V38_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5981..6913)
                     /locus_tag="L1V38_001784"
     CDS             complement(5981..6913)
                     /locus_tag="L1V38_001784"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBN1316333.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="L1V38_001785"
     CDS             complement(6910..7686)
                     /locus_tag="L1V38_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBN1316334.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="L1V38_001786"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="L1V38_001786"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBN1316335.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="L1V38_001787"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="L1V38_001787"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBN1316336.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="L1V38_001788"
     CDS             complement(12011..13291)
                     /locus_tag="L1V38_001788"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBN1316337.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="L1V38_001789"
     CDS             complement(13310..14236)
                     /locus_tag="L1V38_001789"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBN1316338.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="L1V38_001790"
     CDS             complement(14249..15532)
                     /locus_tag="L1V38_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBN1316339.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="L1V38_001791"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="L1V38_001791"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBN1316340.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="L1V38_001792"
     CDS             complement(16320..17231)
                     /locus_tag="L1V38_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1316341.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="L1V38_001793"
     CDS             complement(17228..17692)
                     /locus_tag="L1V38_001793"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBN1316342.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="L1V38_001794"
     CDS             complement(17697..18395)
                     /locus_tag="L1V38_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1316343.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="L1V38_001795"
     CDS             complement(18382..18768)
                     /locus_tag="L1V38_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316344.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="L1V38_001796"
     CDS             complement(18915..20585)
                     /locus_tag="L1V38_001796"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBN1316345.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="L1V38_001797"
     CDS             20768..21001
                     /locus_tag="L1V38_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBN1316346.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="L1V38_001798"
     CDS             complement(21100..21531)
                     /locus_tag="L1V38_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBN1316347.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="L1V38_001799"
     CDS             21610..22023
                     /locus_tag="L1V38_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBN1316348.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
BASE COUNT         6229 a         4922 c         3889 g         6983 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taa
//
LOCUS       DAFLWZ010000045        21975 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000045 DAFLWZ010000000
VERSION     DAFLWZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.045"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            278..787
                     /locus_tag="L1V38_001800"
     CDS             278..787
                     /locus_tag="L1V38_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1316349.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="L1V38_001801"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="L1V38_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1316350.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="L1V38_001802"
     CDS             2322..3302
                     /locus_tag="L1V38_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1316351.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="L1V38_001803"
     CDS             3424..4842
                     /locus_tag="L1V38_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBN1316352.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="L1V38_001804"
     CDS             4913..6382
                     /locus_tag="L1V38_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1316353.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="L1V38_001805"
     CDS             6392..6859
                     /locus_tag="L1V38_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1316354.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="L1V38_001806"
     CDS             6895..7767
                     /locus_tag="L1V38_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1316355.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="L1V38_001807"
     CDS             7848..10382
                     /locus_tag="L1V38_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1316356.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="L1V38_001808"
     CDS             10538..11311
                     /locus_tag="L1V38_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1316357.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="L1V38_001809"
     CDS             11304..12095
                     /locus_tag="L1V38_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1316358.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="L1V38_001810"
     CDS             12105..12596
                     /locus_tag="L1V38_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316359.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="L1V38_001811"
     CDS             12614..13024
                     /locus_tag="L1V38_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1316360.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="L1V38_001812"
     CDS             13028..14428
                     /locus_tag="L1V38_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBN1316361.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="L1V38_001813"
     CDS             14451..14825
                     /locus_tag="L1V38_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1316362.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            15314..15508
                     /locus_tag="L1V38_001814"
     CDS             15314..15508
                     /locus_tag="L1V38_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316363.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            15498..15851
                     /gene="tnpB"
                     /locus_tag="L1V38_001815"
     CDS             15498..15851
                     /gene="tnpB"
                     /locus_tag="L1V38_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBN1316364.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            15953..17500
                     /locus_tag="L1V38_001816"
     CDS             15953..17500
                     /locus_tag="L1V38_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBN1316365.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            17652..18080
                     /locus_tag="L1V38_001817"
     CDS             17652..18080
                     /locus_tag="L1V38_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1316366.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            18067..18309
                     /locus_tag="L1V38_001818"
     CDS             18067..18309
                     /locus_tag="L1V38_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316367.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(18609..18824)
                     /locus_tag="L1V38_001819"
     CDS             complement(18609..18824)
                     /locus_tag="L1V38_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316368.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            18931..19245
                     /locus_tag="L1V38_001820"
     CDS             18931..19245
                     /locus_tag="L1V38_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316369.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            19349..20527
                     /locus_tag="L1V38_001821"
     CDS             19349..20527
                     /locus_tag="L1V38_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1316370.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            20930..21223
                     /locus_tag="L1V38_001822"
     CDS             20930..21223
                     /locus_tag="L1V38_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBN1316371.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         7584 a         3213 c         4370 g         6808 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag agtaagcgcc
    15241 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
    15301 ctggaggttt tctatgtata aattaaatga gattgttcct gtccaattag gaaacgaaaa
    15361 gagtgcacca gaaaaaggta aacccgcggc tgccaagtta gcgatgcgca tcaaaagaga
    15421 gaatggttct gaagttttga tctataacgg tattaacaat tatattcttc aagctatttt
    15481 gaaagaactg ttgtccaatg ctttatgatt tacttcaaac caaacatatt tatattgtgt
    15541 gcggaaaaac agatttgcga aaaggaattg atggtcttgc cagtcttatt caacaagagt
    15601 atcaactcga gctttacgaa gatgccgttt ttttattttg cgggaaccgt caagaccgtt
    15661 tcaaacttct ctattgggac ggtgatggtt ttcttctctg ttataagcgg atagaaaacg
    15721 gcaagttaaa atggcctcgg acgaaagacg aagttcgaac cttaacgaac caacaggttc
    15781 gatggttgtt agaaggatta agtatcgatc aacctcgagc tattttgcca ggaaaaaaag
    15841 gagtttttta agctgggggg ttaacacaaa aaatgtgttg aacccctatt tcttgtgcgt
    15901 ttcttgtggt attctgtaac aaaatcagtt cgattcaagg tggtgaaaaa ttttggaaac
    15961 tacagatacg ttgcttcagt tgcttcaaga agcccataaa accaatcaag cacaacaaca
    16021 aaccattcag aatcttacaa ctgaaatcca actattgaat gaaaaggtca attatttaac
    16081 caacaaatta tttggacgct ctaaagagac tctctttgag gaaacgaatg ggcaattgaa
    16141 tctttttagt gatgaagaaa tttctgtaag tgttccagaa gcagctgcca ccattattcc
    16201 agtaaaagga catcaacgag ttgtaggaac gaaagcagac aaaatcaaac acttacctat
    16261 aacagagaaa gaacatctcc ttcctttgga agaacaattt tgtgaacatt gcggttcaca
    16321 gatgaaagat atcggacgga caaaagtacg agaagaaatt cgtttccatc aggctatgtt
    16381 ggattgtctc acccattatc aacataccta ttgttgtaaa agctgcgaaa aagaaggact
    16441 ttcttctttt aaaaaagcga tcgttcctaa acctttgatt tctaatagct taggttccaa
    16501 tagtttagtg gcggaaacga tccggatgaa atttggtcag aaagttcctg cctatcggca
    16561 agagaactat tggaaacaaa cacatgggtt ggatatttcg agagataata tcaccaattg
    16621 gcatattaaa gcagtgcaaa acgcgttaga ccctttagga gaacgattaa gagtctatct
    16681 taatcaagaa gagattctac acggggatga aacaagttat cgtgtgattg aaagtgccaa
    16741 aacagatacc tattactggc agttttgtac aggaaaagac agtcagcatc ccatcgttta
    16801 ttatcaccac gacgaaagtc gtgctggaga tgttccgaaa acttttctca aggagtttac
    16861 agggtattta cactgtgacg gctatagcgg gtataatgcc gtggaaagtg tacgacttgt
    16921 ctattgtttc gcgcatgttc ggcggaaatt tttcgaagca attccaaaag gaaagaaaaa
    16981 cacggatatt cccgcagctc aagcagtcaa acaattggat aaatggtttg tcctagaaaa
    17041 gaaatggaaa gacttttctc ctgagaagcg attaagctgt cggcaacaag aactgcgtcc
    17101 attatttatt gctttttatg agtggatggc aacgatagat cctgttgcaa aatccaagtt
    17161 ggatgcagcc gttcaatatg cgtgtaaact acgaagtggt tttgaaccta tttttgaaga
    17221 tggtcgttta gaactcacaa ataatcgtgc ggagcgaaat atcaaagagc tggtgatagg
    17281 acggaaaaat tggttgcatt ccacaagtct tgaaggagca cgaacttcag gaatcattct
    17341 gagtgtatat aaaacagcag aacttaacgg attgaatcct gtaaagtatc tagagtttct
    17401 atttgataag ataccaaatc ttcccgtact ttcagcagaa actttagatc aactgttgcc
    17461 ttggaacaag gatgtacaac aacatttttc tcgtaactaa aaacgccaaa cattcccgat
    17521 tctattctat aggtcgggtt atttgacgta caggtactgt tctatggggc gcttacctcc
    17581 tagattgtag taataatgga aagggataga agtaaaacga gttgaatgaa ttttttgagg
    17641 gggagaatat tatgggcgac tcagaggaaa cccacattca acatacgttt gacagttttt
    17701 gtaagaaagt agtctgcaat gaggcgttaa atattcaaaa gaagtacgct agatttcgcc
    17761 aacggcaaat atcaatggaa atattggaac aaaaagggtt aggtacagag ttctattatt
    17821 tggaaccaaa tttgaatagt agtggtactt ttattgtcct tggtatgaaa atctttattt
    17881 ccaatgagga gttggcaaat gcgattgcag cattacctag tcaaagacaa gaaatcattt
    17941 ttatgtcctt cttcatcggt cttaatgatc gtgaaattgg cgatattatt gggaaaagtc
    18001 tcggcagtgt ttggtaccaa cgacaaatgg ctttggaaga gctaggaaag tatttgggtg
    18061 tcaaatatga agcaaaataa acgatatata ccattcatac cactaacgac aatcaaagcc
    18121 gcagcttctg gtgattcaat tgccatgtcc atcgttctgt caaaatatca aaattatatt
    18181 tcacggttag ccatgaaacc agtttatgaa gaagaaaaag gaatggttat gtatgtagat
    18241 gaatatatgc gtagacaact ggaaacaaaa ttgattgaga agatacttga atttgataca
    18301 actcgttaaa gtattttttc cctttccttt tcattctatg gaagtttttt atcgggtcaa
    18361 aataaaggat ttccataggc tgaaaatagc ctagcgctct ttgacaaatg aatagcaaat
    18421 ctatcagtac atgtagattt tgattctcta gttacgccat gacaaggtta gcttttaagc
    18481 gacaaatttt aatatgagaa tcgcgactac gataatgata cttccgtaac caaatcggcc
    18541 cgccattact ggggggaggt gagattccta tgtgctttgg caaaacagct gatagatcag
    18601 aaaaactact atttccatat ttcgattttg gttggcatat ttttcatgcc aaattctgtg
    18661 attttaatag catcggcaag atttaatttt tcttcagctc tctctccact tttaagtttt
    18721 tttactgtac tcaagttgat tcctgttccg aatgctattg cattagccgt agatttttca
    18781 agaatttctt taattatttt tatgtctgca attccttgtt tcatattaaa aattcctctt
    18841 ttctagtccg ttttgatgga gtactggagt gtttttttac aattttaagg ggtaccgtgg
    18901 tggtcgtttt gattttgaga gagaagggtg atggagttgg aagttaaaac aaatgttaat
    18961 tctctggaaa tagagttcta ttcaatttta caaaaaaaac tggaagatta cacggaaaaa
    19021 ttgcttgcag tcagtcattt acctctggta ttaacaaata ctgatttaaa gcgactattt
    19081 cagataagtg atagtacact gaaccgttta gtaaaacttg gtgagtttcc tccctgttgg
    19141 tacgggattc gaggacacta ttttcgtgat gatgttttag aatggatgag aaagagtgat
    19201 tcgaatgact atcgagaaaa attgcgacta cttcgatctt tataagttac attttctttc
    19261 taagatgcgg tacaatgatg acatagatag aaagatttcc aaagggtttc tgcttgttgg
    19321 gttccttcaa aataggagga atcaataaat ggaaaaaaca gatcgattca agaagcaaat
    19381 cagttctact ggtaggatca catggtactt tcaagcatat cgaacaacaa gacgtggctt
    19441 taattcaaaa cgtgaggcgc aactcgctta tctggaaatg gagaaacaac aaaggcttaa
    19501 gaaaaaaatt gttgcaagca atgacaagtt tagtgttgta ggtgagcaat ggttccaata
    19561 ttaccgttcg ttaaatgaac aaaaggaaat aacctatgat aagcgagagg aacaattaaa
    19621 aattattgtt cgatggattg gtgataaaaa gttgtctgat ttgacaccag agtgccttca
    19681 agaattgctt tttaccttaa aggaatgtgg cgttaatgga acaaatgttg gctatgccaa
    19741 aaatagttta caatcactta ttcaagttct aaatatgatt tttaaatatt gtcaaagaaa
    19801 gaatttgata agtgaaaatc caatgaagtc tgtgagaatg ccaaaatatc agttaacggt
    19861 aactgattta aaagaagcca taaataatat tgaggacaag tttcttactg tcgatgaatt
    19921 gagaactttt ttgaattatg gcattgttca tgaggaatta ccgatgtctg tacttttcca
    19981 tgttctattt tacactggct gccgagtcag cgaggcgctt gctctacagc ctggagatat
    20041 agatttcaaa agaaatgaaa ttctgttcta taagcaaacg gcagttaaag gtaagagtaa
    20101 ggattttcga attgaaacta ctaagacagt tagttctgct agacgagttc tagtaactcc
    20161 tctagttatg gaaaagctac aacagttgat taaggctttg ggtgagatga ggcaacatta
    20221 caggtttatt atagaagaaa catatttgtt tgtgtatctt gattctagta aacgtggtgt
    20281 tccttatcgt cgagagtatg taaatgatca cgtcaaacgg tgcgtgaatc gctcaggaat
    20341 taataagcca tttcatactc atttagctcg tcatacaatg gcaagcttag tagcggaaca
    20401 ctgtagctgg gaagtcttga aagatcgctt aggccatact gaccaaacaa cttcgaaaat
    20461 ttatcgccac ttaacgtcaa atgaaaaggt aaaacctctg attgctttta gttctttaga
    20521 gagttaaaaa aacggtgaaa gcactggtat tacaggattc ttgaaaaacg attttttaac
    20581 aaattagtca atatgtagtc agaggtaata aaaatccttt tatatcaata ctttaacgac
    20641 ttttcacaag tatcaaagaa atccgtcgtt aatcattgtt atcagactga gaaagaaccc
    20701 ttggtattca agggttcttt tttcttagca tgtaatttga acaccctgat ccagtttttt
    20761 ctttaattat tggtagggga gaataatgga ttagaataaa tctacctata agtagtagta
    20821 aaaaaaagag cactatgata atatctttct taagagtaac cgctttaata aaaaatccag
    20881 aatattctaa cataaatgga gtattcttag aatcaaaagg agaaagaaga tggtttatac
    20941 ttatacggag caagaaaaga tgaaagtttt agacacattc atgaatgatg gaaaagtaaa
    21001 acaagtacca agttcaacaa aaaagaaata catcctattg aaagaagtct tgaaacgctt
    21061 tgaccatgga gtgacttata cagaaacaga ggttaattcg atactgctga acgtattttc
    21121 tagtggcgat tatgtcgaac aaagacgtta tctaatcaca tttggctttt tcaaaagaag
    21181 ttcagacggt cgggcatatc agatgatggg aattgaaaat tagaagtttt aatttatact
    21241 cattgaaaaa agttcaagta tgcgatattg gttctacacc gcatacttga actttttttg
    21301 tcatctgtat ctataataca aagccaagaa cgttattcaa aatatggata gctatgataa
    21361 aagctaatga gcgattcgca gttaaataag caatcgtcag taaaatcgtt ccaggagcgt
    21421 acatgaaaaa atcaattgga tgcgttacat gaataaagat aattctcttt tatttgtacg
    21481 aataaatacc aaaacgtacc tcctaaaatt agattttgga cagatgccct ttaaaaagat
    21541 aacaagattt cgttcttgaa acaatatata tgcttttatt ccaatgaggt tgtgaaaaca
    21601 gtattttgtc ctgagcgtta gaaaattgaa aatggggaat agcaactcgt actttaccat
    21661 tttttaagtg aatacaagat cagctaattg aacaccgttt attcgtgatg agggacacaa
    21721 cactgcagtc gacacatttc tcttttatgt tcaaagataa caaatattta aaacaaagaa
    21781 aaatagtaga taatcccgtc ctaactcttt tattcttccc tcatagcttc caaatttaag
    21841 caatacttca attaatcaag ttttatcttt ttttttcaat aatcgtaaaa aaagagtatt
    21901 ttttatttaa aaataaaatc tttgtattaa aggacaagac taaaataacc ttagaataaa
    21961 aagagaaaaa aagcc
//
LOCUS       DAFLWZ010000046        21424 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000046 DAFLWZ010000000
VERSION     DAFLWZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.046"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(231..842)
                     /locus_tag="L1V38_001823"
     CDS             complement(231..842)
                     /locus_tag="L1V38_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1316372.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(965..1090)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(1172..1888)
                     /locus_tag="L1V38_001824"
     CDS             complement(1172..1888)
                     /locus_tag="L1V38_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1316373.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(1894..2463)
                     /gene="scpB"
                     /locus_tag="L1V38_001825"
     CDS             complement(1894..2463)
                     /gene="scpB"
                     /locus_tag="L1V38_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBN1316374.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(2447..3244)
                     /locus_tag="L1V38_001826"
     CDS             complement(2447..3244)
                     /locus_tag="L1V38_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBN1316375.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(3214..3585)
                     /locus_tag="L1V38_001827"
     CDS             complement(3214..3585)
                     /locus_tag="L1V38_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1316376.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(3604..4491)
                     /gene="xerD"
                     /locus_tag="L1V38_001828"
     CDS             complement(3604..4491)
                     /gene="xerD"
                     /locus_tag="L1V38_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBN1316377.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(4587..5060)
                     /locus_tag="L1V38_001829"
     CDS             complement(4587..5060)
                     /locus_tag="L1V38_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1316378.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(5165..6028)
                     /locus_tag="L1V38_001830"
     CDS             complement(5165..6028)
                     /locus_tag="L1V38_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1316379.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(6224..8323)
                     /locus_tag="L1V38_001831"
     CDS             complement(6224..8323)
                     /locus_tag="L1V38_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1316380.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(8543..9652)
                     /gene="rpoD"
                     /locus_tag="L1V38_001832"
     CDS             complement(8543..9652)
                     /gene="rpoD"
                     /locus_tag="L1V38_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBN1316381.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(9676..11517)
                     /locus_tag="L1V38_001833"
     CDS             complement(9676..11517)
                     /locus_tag="L1V38_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBN1316382.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(11699..14014)
                     /locus_tag="L1V38_001834"
     CDS             complement(11699..14014)
                     /locus_tag="L1V38_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1316383.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(14199..15059)
                     /locus_tag="L1V38_001835"
     CDS             complement(14199..15059)
                     /locus_tag="L1V38_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBN1316384.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(15118..15639)
                     /locus_tag="L1V38_001836"
     CDS             complement(15118..15639)
                     /locus_tag="L1V38_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBN1316385.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            15917..16678
                     /locus_tag="L1V38_001837"
     CDS             15917..16678
                     /locus_tag="L1V38_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1316386.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            16704..19295
                     /gene="mprF"
                     /locus_tag="L1V38_001838"
     CDS             16704..19295
                     /gene="mprF"
                     /locus_tag="L1V38_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1316387.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19483..20670)
                     /gene="tuf"
                     /locus_tag="L1V38_001839"
     CDS             complement(19483..20670)
                     /gene="tuf"
                     /locus_tag="L1V38_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1316388.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            21038..21394
                     /locus_tag="L1V38_001840"
     CDS             21038..21394
                     /locus_tag="L1V38_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1316389.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         5881 a         4483 c         3740 g         7320 t
ORIGIN      
        1 tcaggttttt aaagctttct tctttttcat tgtagcgttt cctttttttt ataaacaaac
       61 attttcgtct tttaaaagga gaagaatttc acatttgcaa agaattgatt gatttttatg
      121 cataaatcaa aaaaatactc aaaacaaaca aataaaacgt ttacattatt gcatgtcttg
      181 tatttttttc caaaaaaaaa gaccaagaaa tttcttgatc tttttgatat ttatttgact
      241 gctgtatgac gttgttcgaa ctgatgttgt tttcgactta accatggaag aagttgcgca
      301 tgcagcacta aaaagacagc actcacgatg aatcctttga tcaagttgaa aggaacgatc
      361 ccaatcagta catagtttgc taaagacatg cccagcatct gtgttgcgtt cagccctaaa
      421 aacattaagt aaagaggcgt aataacgaaa taatttgcga tactcataaa aatagttaga
      481 gcgatggttc ctgtaatgac acctaaaaat ttgtttcttc ctttatgctg tttctttaca
      541 ctaaagaaat aataaatcgg gaatgtaaag atcgttgttg ataagaaact agcagtgtct
      601 cctaccaaat tatccggaga aaaacctgta gtcagcagat gtaatactga acgcaagaac
      661 gctgttgcaa ctccggccgc tggaccgaat aagaacatgc tgatcaatac cgagatatca
      721 ctaaaatcga tcttcaaaaa actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa
      781 actaatgcga tcgcagcaaa catcgctact gcaaccattt tctgtacacg ggtgttcttc
      841 atttgaaatc ctcctgttag gactcctctt cagcgaactt tttgacgttt ctctccaaat
      901 gaaaaaactc tattttccag ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa
      961 taagctctat cttctttatc cagactatac tgtcggtatc ggaatttcac cgattcagct
     1021 atttttttgc aaaataggtc gtggactata accaccggtc gggaatttca ccctgcccct
     1081 gaagacgaac cttatataat ttttgtttac atattcatta tacatatcta ttcaaaaaac
     1141 gcaacatcta acacttataa aaagtaagtg ttcattttga gtggttcagc aaactgctga
     1201 cttctttttt gttcagttca cggtaatccc caggacgtag gccttgtaaa gtcagatctc
     1261 cgtatttttc acgttttagt ttttgcacag gaagaccaac tgcttgaagc atatttttca
     1321 cttgatgatt acgtccttcg tggatcgtca attccacgat actgtggttt gtcttaggat
     1381 ccactgataa aatttggaat ttagctggag atgtttttcg tccttcgatc tttattcctt
     1441 ttgtcaaagg tgcaagcatc gattttgtag cgatcccttt tacctttgca acgtaaactt
     1501 tatccacttc atgttttgga tgtgtcaggc gctgagcaaa atctccatca tttgtcagta
     1561 gcaagatccc cgaagtatcg taatccagtc gacctacagg atagatacgt tcttttacca
     1621 tcggcaaaag atccgtaaca acttttcttc ctttgtcatc tgcaacagca gaaataactc
     1681 ctttaggttt gtacaataaa tagtaaccgt attcttcttg ataaattggg acttcatcca
     1741 cttccacagt gtcatgtttc ccaactttta tccctaattc ccttacaact tgtccgttta
     1801 cttttacacg tcctgcaagg atgaattctt ctgcttttcg acgagaagtg atgccagcgt
     1861 gggcaattac tttctgcaat ctctccatta caattattct cctttattca ttccatcaaa
     1921 gaatagatct ggtgacacgt cttcttcaag tgaaatttcc atttcttgtg tatcaggcag
     1981 ttcttctaat gatttcaaac caaaataatc taagaagtag ccagttgttc catataatat
     2041 cggccgacct ggtccttcta ctctaccttt ttcttcaatc agtttatggg cagctagacg
     2101 ctgtaccgct cctgaaacct gaactcctcg aatctgctcg atttcagctc ttgtgattgg
     2161 ctgtttataa gcgatgattg ctaaggtttc gacggcggct tgagataatg tgtttgatgt
     2221 cccttgcgca tatcgcttaa gtaagggagc cagctctttt ttagtcgtta atacataatg
     2281 gctttccgtt tcaaaaatat gcaaagctga gtgcgagttt tgagtgtaag attcttttaa
     2341 ttctttcact aaacttgtga cttctgcttc gctgagattt aacagtccgc ttaattcttc
     2401 attactgatc ccttcctcgc caacaataaa aagaagggct tcaagttcac ttaatttcgt
     2461 catgttcggt atctcctact gctggataaa gcataattga ttcatagttt tctttttgtt
     2521 gcgcaatgat ctgccctttt ttcatcaatt ctagcaaagc cataaaagta gtgacaactt
     2581 cacttttaga aggtgactca aaaaaagaat cgaaagtaca gccatgcgca tttcttttta
     2641 tacgctcttc gataaatacc attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt
     2701 tttccacttt ttgagaaaat ttcttacgtt ctaagatttt ctgcatggca cggatcaaat
     2761 cgattttttt gacttgtcct cgcttcaacg gcttttcagc atccgctaac ccatcgatgt
     2821 tcataggttc ttttgtgtaa taaagacttc gttcctctgc tttttctgtc agtctttcag
     2881 ctgcatattt atatttacgg tattctaaaa gctgagtgac caattcttct cgaggatctt
     2941 cttcccataa ttcttcatcg tctgtgacga attcttggac aggaagcaat gtcttgcttt
     3001 tgattgccat caatgtagca gccatcacta agtattctcc tgcaacagct agctcgagtg
     3061 ttttcattgt atggatataa ttcatatatt gctccgtgat cgtagcgatc ggtatatcat
     3121 atatatcgat ttccatttgc tgaatcagat gaagcagcag atcgagagga ccctcgaata
     3181 catctaattt aatattgatc tccgtcaact cattcactct ttcttctttt tctttgctag
     3241 ccattttcca atgtaaggct ctgtgatttc agttgcacgg atggagacat ccgggtactt
     3301 ttcctgtaat tcatctaaca tttgaaagcc catattctca ccgcgataag acggattcaa
     3361 agaaatgtca tggatgatca gctgatcgtt cgttgcccag taaataccaa taatcccttg
     3421 aatgttggtt gaaccttctg gcgtaaagaa aaaaagttca taatcgtctt cagattcgta
     3481 cgtatcaatc tccttcaaca aagaagtttt acctgtcagt ttcttatgga aactcaatag
     3541 tcccatagca attttacggt tttctttccg gtaatgtgtt aacatcttct caccttccta
     3601 tgactaagcc cttggaaaat gctgcttata aacatccgtc attcttttct tcgtgatatg
     3661 tgtataaatc tgagtcgtag agatatccgc gtgacctaac aattcctgta ctgtccgcaa
     3721 atcagctcca ttttctagca gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac
     3781 ttctttgtaa atcccagcct ctcgtactaa ctgcttcaga tttttccaga ttccttgccg
     3841 agaaagacct ttcccatgat tattgacaaa tacatgcatt tcagatgcgt cctttacaag
     3901 taatggacgt gcttcgtcta agtagcgttc cagccattgg atcgcataat cacctaaagg
     3961 aatgatccgc tctttatctc cttttccaac tgtctgtacc agtccaagag aaagatgaag
     4021 atctcccaat ttcaatccaa tcaattcact gacgcgcatc ccagtagcat acatgacttc
     4081 caagattgca cgatctctta tccctaacgt ttttgtcgta tcaggtgctt caatcagctt
     4141 ttctacttct gtcagagtca atgtacttgg taatttctgt gctttcttcg gcgtatcgat
     4201 atgttgcatc ggatcatgat cagtgatacg ctcttgccgt aaaaactgat ggaatcttct
     4261 gagacttgag atcatccgag taacagttgc tgtcgctttt ttttcttcat gcaacttctc
     4321 cagaaaacgg atgactaaaa agcgatcgac atcctgccat gaagcaattt tctgctcctg
     4381 tagaaaatgc aagtactgtt ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa
     4441 tccccgttca atattcaagt agtggagata atcgttgatt tgctctttca taataatccc
     4501 cctcatgcct ctctatcata tcagataccg cttcattctg atagtctttt tccataatct
     4561 gagcaaagaa aaagccgtct agacactcag acggactggt ttcttttttc tttttcatag
     4621 cattcctgac agattccatg gaacgttagc cgatgatctt ttactaaaaa atgataacgt
     4681 tcttctacta cttgctccac ttcaagtaaa agatcctctt ctacttcctc gatcgtgccg
     4741 cagttcaagc atagtaaatg atgatggaaa tgtttggcgc cttcttttct caaatcataa
     4801 cgggctaatc catcattaaa acttacttta tcgacaattt tcaattctgt caagatttca
     4861 agggttcgat aaacagtagc aagtccaatt tccggactct tttttttcac taaaaagaag
     4921 atttcttctg cagataaatg ctctttctca ttttccaaaa gcacaagcag agtagcttct
     4981 ctttgcggtg tcagcttaaa ccccgcttca tgtagctgct gttttgtttt tttcatcgcc
     5041 gaaatagcat tcatgaccat ttactcaacc ccaacaattt ataataatta caaataaaaa
     5101 aagatataac actatgttaa ttaaaattat tataagctag ttaagaaaaa catgcaaggg
     5161 attctcaatt agattttttg actagttttg tcacaccgtt ttcttgtgta atcaatcctt
     5221 gtttcaaaag attacctaat gcgcgcttaa atgctccttt gctgatacca aaagctttca
     5281 tgatttcttc tggatccgat ttatctgtaa agttgatttg ctgatctgca gaacgttcta
     5341 aaatggttaa aatcatttgt gcatcatctg atatagcttc atatgctctt ggcttcaatg
     5401 aaagattcag tacaccgtct ggtcggacac caatcactcg accttttatc tgctcgccta
     5461 gacgaggttc attatatcgt tcagaaggat ggataaaccc aagatagaaa tcttccgtta
     5521 aaacgtacgt acctgttaat ttcaagcggt atgctgttcc tatcacatct ttgtttttca
     5581 tttcttctgt tccatatttg cttaaagatt tgaatatttt ttcatctgct aaactgcccc
     5641 aaatacggtc ttttgcatca actctaaggg aaatcatcaa gcgatcccct tttttaggcc
     5701 atagctctgt cattgtcggc aattcatcaa gagatacgac aaagtcttta tctggaagac
     5761 cgatatcgac aaacgcacct aaatcttttc gtgtagcagt aacgattcca aaagcgtaat
     5821 gaccgatacg gcttttagga atttgtgtag tgatccgatt ttcatgtttt tgattttggt
     5881 aaccgaatcc ttcaactgct tcaccgattt tgtgttcacc ttctgatttg cttaagccaa
     5941 aggtttgtcc gtttttttgg acaaagtagt ttttttcatt ttcatcaata ataatacctg
     6001 taaatatagt tgctaataaa tcgttcattt ttttctccct ctatagtgaa aggttttctt
     6061 aatacatttc tttgctatca taacataatg ttatctactt gaatagctga gccttggttt
     6121 ggaaaggtga aaaaaggagt atgacaacag ttgtgtcata ctcccctttt tcgaataaac
     6181 ggtgttaaac ggcaggctca cagcctcttt catttgccta aaattaattg ctcccatttc
     6241 ctccgaacca tccagtttta cagttgatgg ttacgatgta aaatggcaaa gcactttctc
     6301 caatgccttt catcaatgca gattttgttg aagtggcata tagattataa tagccttccc
     6361 cattttcgat tctggctttt tctaatctgt aacctccttc aacgatatat ccacgttgga
     6421 tacatgtagc aatcactttg ctttggacac ctggtgccca cgtccatgct ggattagatg
     6481 catcggcaat atcacttgct ctggcagatt tgattggctg attcgctgag tttgaagagg
     6541 aaggggtcga ggatgccgct tcttgctgtg ctgcttgtgc gaccgcagct tgttgagcgg
     6601 cttgagctgc agctgctgct tgagcggctt gttttgcttg ttcttcagct gcttttttcg
     6661 cttcttctgc ttttttcttt tcctcttctt cttttttctc tttatcagtg agcatcttat
     6721 ctacttgttt caattgttca ttcaactgag cagatagatc tgtatttttc actttttcta
     6781 ctgcttcttt tgccgtcttg tattggtcgc gtgttgctga atccactact tttccgtctt
     6841 taaagactat agctgttttt tctttagctg tttgcaattc agcatattga tttttagctt
     6901 ctgtttgtgc ttgttgaatc aattttccaa aatctgtgtt atccgtttcg attgcttgga
     6961 tctctttatc tgctttcaac ttgatgtcat ctgctagatg atcatcgacg atggcaggtg
     7021 ctatgaacca ctcattcact ttttggatat ctcggatctt agattggata tcttggtaag
     7081 ttgtttctaa ctctgaatat cctttttcat tcttaagact ggataaatca ttttttagtt
     7141 ttgataaatc ttgatgaatc atatctgcac gaataaattg atggtgatca tctgtataaa
     7201 aggcagcaag tttctcatga agttcttcca tttgttgctg tctttttgct tctgctgcta
     7261 cttcggcttc tactttttga tgatggtcat aataagccca gcttcctcca ccgagtagaa
     7321 gtactgctgc taaaacgaga taaggtactt tttttgattt tttcttttgc gctttatctg
     7381 gatctgtttt ttctaagttt gattcttgat gtgttttttc agtatctggc acgattgtta
     7441 ttgatttcgc ttctgcttca aacagcttag gctggttctc ttctttttct atttttgctt
     7501 caagatcagt accctctttg cttacagatt gattttcagc atcggattca ctatttattt
     7561 catcgggctc tgttgacttt ttgtctgtgt tttcgagtat ttcttttttc tctgcttccg
     7621 gcagtttatt cgttttttcc ttttctaatt gtttttcagt aaatacttca gttttttctg
     7681 tgatatccgt ttttacgtct tttattttta ctgtttcttt acctgtggcg ttttctctat
     7741 cagagtcttt ttcagtttct tgttcctttt ctggctctac tttgttttcc tgtgcaattt
     7801 tttcactgat cattttgagc agctctttcg cgtgctcttc ttttgtatct tcacgatgtg
     7861 ctttgatata agcggatagt atcgaatttt cttcctcatt atcgacgatt tctttcagtt
     7921 cagctactct tcttttttgt tttgattcaa gcgtttcttc ttgattcttt cctgattctt
     7981 ccgaagtctc atgaacagtt gctttcttct gttcattttt ctctatatta gttacttgat
     8041 cgtgagcagg tggttcttcg tcttctggtt ctgctttttc gaataattcc attacagatt
     8101 ctagaggtaa atctttcaat tccgaccatt cgattggatc gtttaattct gtatcaggaa
     8161 agactgcatc ttcagttgat ttatcctgca tagctgcatc tgtatttgtt tcttcaattg
     8221 attcttttat ttgctgatct tctgcagtta tttgatgacc gcagtctgga cagatagtat
     8281 tctgctccat ttttttcgat ccgcaatttg gacatttttt catcacttag cgatcggctc
     8341 ctttactagg tttacgctac catttaatct atcatattct atacgtcacg ccaatagctt
     8401 atttttagga tttacttaaa aataatgaat gaatttcctt cctatagaaa aaaaagcttg
     8461 agactgcgta gtctcaagct ttttttcttt taaaataaac caaacagttt tactgatttc
     8521 tcttctggtc aatagtccac gcttattcta agaaatcttt taattgtttt gaacgagaag
     8581 gatggcgcaa ttttcttaat gctttagcct cgatctgacg aatacgttcc cgagtaacac
     8641 caaatacttt ccctacttct tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta
     8701 agcgaaggac attctcttcc cgatcagtca atgtatctag tacatcttcc aattgttctt
     8761 ttagtaactc ataagctgcg tgttctgctg gacttgttgc ttcctggtct tctatgaaat
     8821 cacctaagtg agagtcatct tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg
     8881 cgattttcaa gatttctcgg actttttctg ttggaagatc catttccgca ccgatttctt
     8941 ctggcgtagg ttctcttcca aggtcttgca gcaattgacg ttggatacgt atcaatttat
     9001 taattgtttc aaccatatga actggaatac ggatcgtacg tgcttggtca gcgattgctc
     9061 gagtgatggc ttgacgaatc caccatgtag cataggttga aaacttaaat cctttgcggt
     9121 agtcaaattt ttcaactgcc ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga
     9181 actgcatgcc tcgtcctaca taacgtttag cgatacttac tactaaacga aggtttgctt
     9241 ctgccagacg ctgtttcgct tcttggtcgc cttcttcgat tttcaatgct aacgctactt
     9301 cttcttccgc agttaaaagg gagacacggc caatttcttt cagatacata cgaaccgggt
     9361 cattgatttt tacaccggtt ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt
     9421 tctcagcact cttcaagctg tgaattgatg gatcaccatt ttcatccacc acactgatac
     9481 ctgcgtcttc aatcttttgg atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg
     9541 tagcaagctg attggataaa tcatcatata caacttgtcg tttgggtttg ttttctttga
     9601 tgaaagctgc tactgctgct tcatacgttt ttttatctgt tccatttgcc ataaaagaag
     9661 gccccccttg agtagctatt tggcttgttt taactgtttc gttaaattga tgatttcaat
     9721 cgtcaattca agctcaagct gtttgtttcc agttcgtctg gcttcttgct gcatttgttt
     9781 ttttaatgtt atttcatcag ctaagccaga tttgctgatc acatctagca agtcttggat
     9841 ttctcgtggc gaactttctt ctgccaccgg taaatattcg atttccacca ccaaccgcct
     9901 taaattttca tcttgcaaaa agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga
     9961 gacatatgca tcgaataaaa aataaacttc tgcatatgca tcatgaataa actgaaattc
    10021 tcgttctttt aaaatattac ggacagaaac ttctttaaat gcacgatata atagaatctg
    10081 ctctgccttt tctacttgcg tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac
    10141 ctgagtgtgt tgactttcct gaggttcttg acgattttgc tgatttgtcc ttcgaagatc
    10201 gcgcagttgt ttttgtatcg tctctctgcc gatctgaaac tctgttgaca gttgagatag
    10261 atacatatct tgttcgattg gtgaaacaac tcggctaagt tcaactagta attcttcgag
    10321 gtattcgatc ttgtcttttt cattatctaa atttttccct tgttttaaat aacgtgattt
    10381 aaaagtaaag actgtttcgc gcccatgagc cactaattct tggaaagatg cttctccata
    10441 cttacggaga tattcatcag gatcaagctt ttctggaacg actacgacag aaagtgctaa
    10501 tcgactgttt tgccgaagca attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc
    10561 tccgtcatag caaaagacca attctttcgt cagcttttcc atttgttgga tctgttgagc
    10621 tgttagactt gtccccatag aagctaatcc agttttgata ccagcctgcc atgcagcaat
    10681 cacatccata aacccttcga acaacaaaat ttctccgttt ttccggatat cgcttcttgc
    10741 tttatcaaga ttaaataaaa cttgtctttt attgaacagt tctgtttctg gactattcaa
    10801 gtatttgggc tgatcttttt cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc
    10861 gatcgtctgg ccttgagaat tacgaagtgg aaacatcact ctttgataaa aacgatcaga
    10921 catacggcca tcatcatgcg tgacaaacaa tccagagcgt tctaacaatt catttgaaat
    10981 tgattcattc ttgaatactt gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt
    11041 gaattcttca attaattcta aagacaaccc acgactttgc aaatattcta aagctggctg
    11101 tccagctttt gtatgcaata gcatgtgatg atagatttcc gctgcttttt catgagcagc
    11161 aatcagtttc cccgtagcag attcaggatt ttggacagct atagtacgct gacgccattg
    11221 atcttctaac ggtatctgtt cgaagtctgc cacttttacc actgcttctg gaaaacttag
    11281 accttctagt tcttgaagaa aagtaaacac gtttccgcct ttaccacaac caaagcaatg
    11341 aaaaatctgc ttgtcttctg caacagaaaa agacggtgta cgttcttcat gaaaaggaca
    11401 cagccccaag taatttttac cagacttttt caactggaca tattgtccaa tcacctcaac
    11461 gatattcgtt tgactgcgta ctgtttcgat aacctcttga ggaatccgtt gagccatttt
    11521 ttcaccccct gctctattga tatcttttgg gtttaacaga agatatttca ggagaataac
    11581 cggtaaaaaa tcgcactaac tgaaatcagt gcgattttaa aggacacaat tatacatgtt
    11641 tgattgtatc atatttcatt gctttttcaa gtataacaca tttctatctc attaagcatc
    11701 aatttgctac tcttttcagt aactgatttt gaatatcagc cttccagtac aatactcgaa
    11761 gaacaatatt tacgagcatg aatacaaaga agtatcctac gctctctccc aaccctaagt
    11821 ttacttccaa aattccatgg aacagcattg cagctacata tatccctacg atcgtcgtta
    11881 ctgctaggaa gatgcgcaat gggttgaagg gataacaagc ttttacaact gccatgcaac
    11941 tgatcccaat cagcaagtaa tacatcaaag tagtagtttc agcatttccc catgcgaatg
    12001 tttttccaag tagatacacc gcaatgatat tcactactac aagcaaggca tttggtaaag
    12061 cattaataag tgctgtaggc aaataacggt aagtgatttt tcttttatct tgttcaaaag
    12121 ataaaaagaa ggaaggatac ccttcaatcg ctaaatcaat cagcgtgatt tggataggga
    12181 taaacggaaa tccaattgct gtaacggcac atataatcga taaaataaat gaataaatcg
    12241 ttttgataaa aaagatgcct gagactttcg tcacattgtt gaccactcgg cgtccttcaa
    12301 acaggacttc tggcaatgta gtaaaatcag agtccaacaa taccagattc gcaatctgac
    12361 gtgttgctcc atcaccttct gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa
    12421 catcattcac accgtcgcct gtcattgcaa ccgttctgcc gctttctttc aattcattta
    12481 ccagcaattt cttttgctgc ggactcactc gtccaaaaac cgtatagcga tgagcagctt
    12541 ctcgcacttc catttcttca gtaatttgag aaagatcgac atacgcatca taattcggta
    12601 atcctgcacg tctagcgata ttggagacag taaaaggatt gtctccagaa atcactttca
    12661 gatccacacc ttcctcatga agataagcta gtgtttcttg agcgtttttt cggattggat
    12721 catcgatttc aaacagagca accggctcaa caaatgctgg tttttcttcg ttcaattgct
    12781 gatttggagc gatccccaac ataagtacgc gatagccatt cgcttgggct gtttttagac
    12841 tgtccggaag ccgatcttct tccaccaaac gttcaggcgc tcctacgtac acgactccca
    12901 gttctggaaa ttccatcgcg ccccatttgc gatcagaaga aaatgcgact ttgtttgtca
    12961 catcataccg attagaaagc tcaaaataat ctctcatagc ccgcatagtg atgttgttat
    13021 cactgctttc tgccagatac gtccccataa tttctgggat ggctttctcg tacagcggat
    13081 gtagtgcttc tacccgctgg atactcattt tcccttcagt aatggtccct gttttatcca
    13141 agcataatgt atcgacatgg gccagcgttt caattgaata catgtcttga acaaggattc
    13201 gtttttttgc cagtttggtt acccctgtcg ttaatgcaat acttattagc aataccaaac
    13261 cctttggaag catgcctaac aaagctgctg cagatgcaat aacagaaatt ttgatagaag
    13321 catcgcggat gaacagtgct tccaaaaata gtatgatccc caaaggaata atcacgaaac
    13381 tagtgaattt ggatactttg cgaatcgaat ctacaagttc agaacgaata gctttgtgag
    13441 tctttgcctc gctagtcaag cggacagcat aattatctgc acctactcgg ataacttcag
    13501 ccatgacaga accgcttgtc aaaaagcttc cagaaagcaa ttcagctcca gtttctttga
    13561 caatcaaatc agattcgcct gtcaaaagag cttcatttgc ttctgcccgt ccagatataa
    13621 cctgtaaatc ggctggtatc tgttctcctg ctccgatttt taccaaatct cctaatacca
    13681 gctctttagt agaaatcgat tgttctttac cgtcccggat cactagtact tctgattggg
    13741 aaacaatcga taatttccgt acaagatttc ttgcatgtat ttcttgataa attccaataa
    13801 cgatattgac gacaataatt gctaaatacg ccatgttgga atacgcacct acaaataaca
    13861 gacaaatccc aataccaaag ttcagaaaat tgaataacgt caatatatta tcgctgaata
    13921 tttgttttgt actttttgat gcatcttcct ggtagtcatt ttgctggcca gaagccattt
    13981 tctgaactac ctcttgctgt gtaagtccat tcattttctt tttctccatt ttccgccaac
    14041 tttcaaaaat aatcacgtgt ttaagtctag cgtgttccaa gattaaaaac aacttgtttt
    14101 tataaaattt atagaaaaac acacgaatga ttttacaaaa aagatgccaa cctttttgtt
    14161 tgaatcaccc gtgtgctgtt tttattatca atctatcttt acttatattg ttcctccaaa
    14221 cggctcatcc accaacctag tgctgtaccg gctataaaaa gaacaggaca agctagtacc
    14281 ccagcaactc ccaatcccgc gtaatcggta ggaatgatca taatcgttga agcaaaaact
    14341 acacctaaaa tgaaatggaa tagcttgcta tatgcctttg agaaaatgta atccatgatt
    14401 tttgacaatc caagaacaca aagaatccca ccaattccga tcggcacaat cacttcaagt
    14461 cgtacttctt taaatccgtc agccatcgct ttatacaatc ccatatacac caaaaaatta
    14521 gaagggctca atcctgggac gatcataccc aaaccaatca atccgccggc aatcagccat
    14581 gttccaaaat tctgatcgac ttgcccgtca aataattgag cgccgtataa taaaaacaaa
    14641 taagccagaa caaaagtaac aaccatgatg atcacatcag aagtatctct tccttttttc
    14701 cctgcttctt tccataacgc aggaacagtt ccagcgatac atccgacaaa aaaccataat
    14761 atcgttgttt catacgcacc taataaaaaa ctgactaaaa aagaaagtag aaagatgcct
    14821 gtcactccgc ctagaccaac aggcagaaaa aacaaaacat tttctttgaa attttttgta
    14881 aggtgggcta aaaaagaaat cagccgctca tacatgccaa agacagctgc taatgcacca
    14941 ccgctgactc ctggcaagat aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac
    15001 atccagtctt tggttgtgta ccccacttct tgattttcca ttttttgcct tttttccact
    15061 atttgcgtac tccttctttc atttaatttt attcatgatt gaacatttcc tgctatttta
    15121 cttaaagact ttttcatagg tctctattat tttttcattc attttgacaa tatcaggata
    15181 aaacatgtta cctccattat gatagagata gccgccattg taaagcaagg actggatccg
    15241 ccaatatcgg tattgtttcc cttcctcatt tcctaaaagt gggctcagca catctttaga
    15301 atacgcttct gctaattcta ctgtgttttc tccgccatga ttttttacat aggcaatata
    15361 atctttccca aaattatatg cttggacagc tgtccataaa tcgcatcctt gtttctttgc
    15421 ttctactatc atttccgcca aatatttgac accttgatca atactgtcag ctggattatc
    15481 aatgatctca gcttctccat gcagactttc cgagctctgc atgagatctg tcccttttcc
    15541 ttttgattcg gtcaatatta tcgccttgat caaattctcg tagttttcca tatgataatt
    15601 ttttgcagct gttgttattt ctatttgata gctttccact cgttttaccg aacgataagt
    15661 tcttcctcat aaaaacaaca ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat
    15721 acggataata gataatcgtt ttcgcttcat ttcatcacct agttattttg acatcttttt
    15781 ttatcttact atttctttat cttcttggct atttcttcct tgatttctgt gtacgcctta
    15841 agaaaaaatg aattttcctg tattttttga catcttacga aaatgatcgt tgtttttcag
    15901 taaaaacaat tgcccaatga ctgatataat cgttatactt tacacagtag gtgattatgt
    15961 gaaaaaagaa aagaaatatg caaaaatgcc agatgggagc gaaatttact atgaaaagag
    16021 cggtcaaggc ttccctctct ttttactgca tggcaatgac ggcagcggcc gctttttttc
    16081 agaacaggtc cctgtactcg aacgctacta taccgtgtat ctagtagata gccgaggaca
    16141 tggtcgttcg acaaacgaag catctatgtt gaattttcag ttaatggccg aggatctgaa
    16201 tacgatcatg ttgctggaaa aaatcgatca ggcagatttt cttggattta gtgatggagc
    16261 aaatctagca ctggtatttg ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa
    16321 ttctggaaac acgcttgtta aaggcgttcg tttttctgcc agagtcatca gtaatattca
    16381 ttatgcatgg gtatggttac tctctttatt tcgcccaagt cttcgcaaaa atcttttagt
    16441 tatcaaactt ttgctgcatg acatcgggct tacagaaaat gatttaaaaa aaatcaactc
    16501 ccccactttg atcatcgtgg gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat
    16561 agctaaaact ataccaaaag cttcctttgt gcttgtgaaa gaacaaggac atgaattagc
    16621 tagaaaagat cctgaacgct tcaatcgaga agttcttcaa tttctttctg aaacataact
    16681 attaggaata gaaggtgatt tatttgttaa aaaataccat acaatggctg aaaaaccacc
    16741 taggactgtt caaaacaatc tttttgattt ctgtcattgt cattattgtc ggtgaattga
    16801 tgtccatcgg taaaactcta tctatccagc aattaggaga aacgtttgcc actatacctg
    16861 tatggaaaag cggactaatg ctattgattg gtcttatctc tgtgttacct atggttggtt
    16921 atgatattat tttgaatcgg atgcttgaac aaaagcagaa tcctcgttac ctgtttgaga
    16981 caagctggct gatcaatacg atcaacaata ttgccggttt cggcgggttt gttagtgtgg
    17041 ggcttcgctc tgaactatat ggacaaaaga aagagagcag aaacgtgatc caagcattat
    17101 cgaaagtttt cttgtttttg atggctggac tttctattta cagtctgctt tcttttttac
    17161 ttgtagtctt cacgccagtt gctccttttt tgaagcaata ttggatatgg ttgatcggcg
    17221 gcggtctata ttttcctgtc gtctttttat ttactacttt caaaaagaaa ggattccttg
    17281 gtggtacctc acttaaaact caaggacagc tattgctagt ttcattgttg gaatggaccg
    17341 gtgtcctgtt tagtttcctt tctgttggtt atttaatgga aatccggatt gatctgtggc
    17401 aaacaattcc attattcatt gctgcttcag tgataggaat cgtgtctatg attccaggag
    17461 aaattgggag tttcgatgta atgatgatta tcgggttgtc cgctattggt gtgccaagag
    17521 aaatagtcgt tgtgtggatc ttgctctatc gcctgttcta ctacatcatt ccgtttttga
    17581 ttggaatcgt ctttttcttc aaaaatatcg gttccacttt tgatcagcgt tattctggta
    17641 tccctaaaca attagcaaca gaaattgcgc ataaaatcgt ggttgtctta ttatactttt
    17701 ctggaatcat gctagtactt tctgccacta tcccgcaagc ttttacagag tttcgctggc
    17761 ttcatagttt gaacccattg aaatttcatt ttattatcca atttcctagt atactattgg
    17821 gatttctttt aatcattatg ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc
    17881 ctacaatctt cttgattgtt ctagctttac tttatgtttt attaagtgat tttagtttca
    17941 caccggtggt tttcttgtct attctgcttc tgatcattct tgcttctaaa aacgaattat
    18001 ttcgggaaca attgatctat tcatgggagt ggcgtacgat cgatggaatc attattggtg
    18061 cactgtcctt gctttacatc gttattgggg tatacaatct gccggatttc cctcatcggc
    18121 gtcaccattt tatttccttt ttcttatttc cttctgaaaa gatttggttt tcgggattgt
    18181 tggccatcat cgctgttagt ttcatgatcg ttctatttgt tcatttcctt caaggagaaa
    18241 agaaacagat tggcgaagcc tttaatgaag aaaaggccct gaagatcctt acaacttatg
    18301 gaggaaactc cgatagtcaa ttgatcttct taaaagataa gcggatgttt gcctatgaaa
    18361 aagacggtga accaactgtt cttctccaat tcgcttgctt caataataaa tgtattgtaa
    18421 tgggtgatcc ttctggtaag aaagaagatt ttccagaagc aatcgaagct tttatcgaag
    18481 aaacagatcg actatgctat ttaccagttt tctacgaaac aagcgaagag attgttatga
    18541 ttttgcatga attcggctac gatttcatta agatggggga agaagcttat gtagacctga
    18601 atagttttac aacttcaggg aaaaaaatga agggcactcg tgctgtcttg aatcggatcg
    18661 aacgagaagg atttacattt gatgtcttac aaccaccatt ttctactgag caaatgagta
    18721 ctttcaaaaa tatctctgat aattggttgg gttcacgaaa ggaaaaaggg ttttctttag
    18781 gctttttctc tgaagattat ctacaaagag cgcctattgc agttgtcaaa aatacccaag
    18841 aagaaattgt cgcttttgca acgatcatgc ctacttacac gaacaataaa gtaggaacga
    18901 ttgatctgat gcgatatgat tctaaaaaag caccttctgg cagtatggat ttcttgttct
    18961 tgcatttgtt tgcctatatg aaagaagaac atatccaatg gttcaattta gggatggccc
    19021 ctctttcaaa tgtcggaact tccagaaaga gttttttaca ggaaaggatt gcatacttgg
    19081 tttacgagtt tggttctcat ttttattctt tccatggatt aagagaatat aaaagcaagt
    19141 acgctacaaa ctgggtctca cgttatactc tatattctag agatagttgg attgcatatg
    19201 ttatgattgc tttgctgatt attgataatg cgccagttga gcagacacaa ggtagaataa
    19261 gtggtttgaa aaaatggata cgaagaaagt attaaaaact gcataccgat agatgaacac
    19321 tctcatgatg aataaaagag actgaagtaa aacgaaagtt catgcttcta caatctcttc
    19381 ttatacaatt gaagaacaaa gagcggtcca aacagaaatc ctgtttggac cgctctttta
    19441 ttttaaacat ttttcattac caaaatattc gagtcgcgtt tcttatgctt cgatctctgt
    19501 aacgatacct gaacctactg tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc
    19561 aacagcgatt ggatggatca agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat
    19621 ttctgtatct tctggcaatg tgattgttcc tgtaacatca gttgtgcgga agtagaactg
    19681 tggacgatag ttgttgaaga atggagtatg acgtccacct tcttcttttg tcaacacgta
    19741 cacttctgct ttgaattttg tatgtggagt aatggaacct ggtttagcaa gtacttgtcc
    19801 acgttcgata tcgtcacgtt ggatcccccg taacaacacg cctacgttat ccccagcttc
    19861 cccgtaatct aacgttttac ggaacatttc tacacctgtt acaactgctt tttgtgtttc
    19921 aggtttgatc cctacgatct ctacctcatc accgacacga acagcaccac gatcaatacg
    19981 acctgaggca acagttcctc gacctgtaat tgagaagacg tcttccactg gcaatagtaa
    20041 tggtttatct gtatcacgtt ctggtgttgg gatatattca tctactgtat ccatcaattc
    20101 cataatagca gcttcagcat ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat
    20161 cacaggagtg tcatcgcctg ggaaaccata ttcgctcaat aactcgcgaa cttccatttc
    20221 taccaaatcg atcaattctt catcatcgac taaatcaact ttgttcaaga aaacaatcag
    20281 gtattttaca ccaacttggc gtgacaataa aatgtgttca cgtgtttgag gcatcggacc
    20341 gtcagttgca gaaacaacta agattgcacc atccatttgt gctgcccctg taatcatgtt
    20401 tttcacatag tccgcgtgtc ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc
    20461 atattctacg tgtgcggtat tgatcgtaat cccacgttca cgttcttctg gagctgcatc
    20521 aatactagca tagtcttgag gatttgctag gccttttttg cctaatactg tagtgatcgc
    20581 agcagttaaa gtagttttcc catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg
    20641 tttacttctg tcataatgtt cttttgccat aatttacaaa cctcctaaat aatatagatc
    20701 actgaaaaat ttcagctctc acctttttat tatagtcttt ttttgactaa atcaaaaaga
    20761 atacgtccga cttacttttt gtaagattcg aactaagctt attatacgtc aatattggtc
    20821 aaagtcaact aagagcactc gtctgtctta tacgcgaaaa aagtaccttt tataaataaa
    20881 aaaatgtgtt ttttgagaaa aacttcaaga tagtccttaa ctttcttttg aagcaataag
    20941 aacaaaatga ggaaaagttt aaaattcagc tgttgccaac aactttcaat agacgaaatc
    21001 ttctatttcg ttaataataa ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact
    21061 tgtcgtttta ggcatatttc tcggcggaag ttttgcagct tatcattatt tttacggcgg
    21121 cgaagcttat tatacaaaaa tcacgacgaa tggcgaaatg tcagctaccc aagcagataa
    21181 cggagagaaa ttcacgactt atacctacaa gcaagcggct tataataaag atggtgaaaa
    21241 aaaacaggtg acgcttcgcg aagaaagaga acatccatta aagatgaatg cgtatcttaa
    21301 actcaaagtc aatcctcgta aaggtgtatt aagctgggaa gaaataaagg cttctgaagt
    21361 gcctaaaaat gcggcagaaa aaatcgataa ttagtaaatg gtcttaaaat tttattagat
    21421 aaaa
//
LOCUS       DAFLWZ010000047        20400 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000047 DAFLWZ010000000
VERSION     DAFLWZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.047"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(387..1853)
                     /locus_tag="L1V38_001841"
     CDS             complement(387..1853)
                     /locus_tag="L1V38_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316390.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L1V38_001842"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L1V38_001842"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1316391.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4753..5112)
                     /locus_tag="L1V38_001843"
     CDS             complement(4753..5112)
                     /locus_tag="L1V38_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBN1316392.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="L1V38_001844"
     CDS             complement(5142..5483)
                     /locus_tag="L1V38_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316393.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="L1V38_001845"
     CDS             complement(5480..6154)
                     /locus_tag="L1V38_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1316394.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="L1V38_001846"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="L1V38_001846"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBN1316395.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="L1V38_001847"
     CDS             complement(8668..9858)
                     /locus_tag="L1V38_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1316396.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="L1V38_001848"
     CDS             complement(9879..10406)
                     /locus_tag="L1V38_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBN1316397.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="L1V38_001849"
     CDS             complement(10453..13242)
                     /locus_tag="L1V38_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1316398.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="L1V38_001850"
     CDS             complement(13389..13589)
                     /locus_tag="L1V38_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1316399.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="L1V38_001851"
     CDS             complement(14042..14362)
                     /locus_tag="L1V38_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316400.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="L1V38_001852"
     CDS             complement(14865..15983)
                     /locus_tag="L1V38_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316401.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="L1V38_001853"
     CDS             16454..17761
                     /locus_tag="L1V38_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBN1316402.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="L1V38_001854"
     CDS             17882..19081
                     /locus_tag="L1V38_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1316403.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19108..20376)
                     /locus_tag="L1V38_001855"
     CDS             complement(19108..20376)
                     /locus_tag="L1V38_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBN1316404.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         5906 a         4344 c         3559 g         6591 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    19141 tattggcaaa aagagtatcc cttttctgac cgctacttgc tgagcagaat aaataccgct
    19201 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    19261 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    19321 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag
    19381 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    19441 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    19501 tccattaaat gattcctgca gtaatggaag actcaatccg agataacgtt gtgtttgcaa
    19561 aatcaatgct gcggctacaa ctacagcccc acctatcgta tttcgccaaa caggatgagg
    19621 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    19681 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    19741 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca taaaatttgc
    19801 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    19861 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    19921 actgattcca ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc
    19981 tgtattatct gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc
    20041 tccaaataaa tgggtagtta tggttccaaa cagtgtaagt ggaataagtc gcaacgggat
    20101 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    20161 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    20221 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    20281 taagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    20341 taaaatgcgt actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa
//
LOCUS       DAFLWZ010000048        19798 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000048 DAFLWZ010000000
VERSION     DAFLWZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.048"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..168
                     /locus_tag="L1V38_001856"
     CDS             <1..168
                     /locus_tag="L1V38_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBN1316405.1"
                     /translation="VFWGAYALWGMNPWLFSFVMNGASGLSTAIVTIIVLLGIQQTTP
                     SIFVPDKRQEL"
     gene            complement(249..1022)
                     /locus_tag="L1V38_001857"
     CDS             complement(249..1022)
                     /locus_tag="L1V38_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316406.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            1289..2989
                     /locus_tag="L1V38_001858"
     CDS             1289..2989
                     /locus_tag="L1V38_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBN1316407.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            2959..3177
                     /locus_tag="L1V38_001859"
     CDS             2959..3177
                     /locus_tag="L1V38_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBN1316408.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            3197..4087
                     /locus_tag="L1V38_001860"
     CDS             3197..4087
                     /locus_tag="L1V38_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBN1316409.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            4105..4389
                     /locus_tag="L1V38_001861"
     CDS             4105..4389
                     /locus_tag="L1V38_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316410.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            4876..5490
                     /gene="gmk"
                     /locus_tag="L1V38_001862"
     CDS             4876..5490
                     /gene="gmk"
                     /locus_tag="L1V38_001862"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBN1316411.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            5495..5800
                     /locus_tag="L1V38_001863"
     CDS             5495..5800
                     /locus_tag="L1V38_001863"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1316412.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            6053..8461
                     /gene="priA"
                     /locus_tag="L1V38_001864"
     CDS             6053..8461
                     /gene="priA"
                     /locus_tag="L1V38_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBN1316413.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            8476..8967
                     /gene="def"
                     /locus_tag="L1V38_001865"
     CDS             8476..8967
                     /gene="def"
                     /locus_tag="L1V38_001865"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1316414.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            8960..9898
                     /locus_tag="L1V38_001866"
     CDS             8960..9898
                     /locus_tag="L1V38_001866"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBN1316415.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            9898..11256
                     /gene="rsmB"
                     /locus_tag="L1V38_001867"
     CDS             9898..11256
                     /gene="rsmB"
                     /locus_tag="L1V38_001867"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBN1316416.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            11269..12009
                     /locus_tag="L1V38_001868"
     CDS             11269..12009
                     /locus_tag="L1V38_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBN1316417.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            12006..14075
                     /gene="pknB"
                     /locus_tag="L1V38_001869"
     CDS             12006..14075
                     /gene="pknB"
                     /locus_tag="L1V38_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBN1316418.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            14240..15139
                     /gene="rsgA"
                     /locus_tag="L1V38_001870"
     CDS             14240..15139
                     /gene="rsgA"
                     /locus_tag="L1V38_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBN1316419.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            15152..15802
                     /locus_tag="L1V38_001871"
     CDS             15152..15802
                     /locus_tag="L1V38_001871"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBN1316420.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            15803..16441
                     /locus_tag="L1V38_001872"
     CDS             15803..16441
                     /locus_tag="L1V38_001872"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBN1316421.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            16596..17450
                     /gene="mreC"
                     /locus_tag="L1V38_001873"
     CDS             16596..17450
                     /gene="mreC"
                     /locus_tag="L1V38_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBN1316422.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            17454..17963
                     /gene="mreD"
                     /locus_tag="L1V38_001874"
     CDS             17454..17963
                     /gene="mreD"
                     /locus_tag="L1V38_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBN1316423.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            18218..19792
                     /locus_tag="L1V38_001875"
     CDS             18218..19792
                     /locus_tag="L1V38_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1316424.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         6685 a         3623 c         4224 g         5266 t
ORIGIN      
        1 gttttctggg gagcgtatgc actatggggg atgaatcctt ggctcttttc tttcgtaatg
       61 aatggtgcca gcgggttgag tacagctatt gtaacgatca tcgttttatt agggatccaa
      121 caaacgactc cttcgatttt tgtgccagat aaacgacagg agctgtaaat aaaaaagaag
      181 caagaaactt gagacagaat catgtcctag tttcttgttt cctttttatt ttttgataag
      241 aaatagatct acttcaatgg cagataagaa agatcggcat cttctaccaa ttgccagtgt
      301 cgatcggtga cagagtagat taaagtagcg atgatttcct cttctcgata ccgggtgcct
      361 tttaatttcc aaatataatc ttcaatcaca tagattggga tacgatattt accatcgatc
      421 aaaccaactt gatcaaaaga aaaaatgatc ccttcctgca tcaaattacg catttctttc
      481 aataattcca cactgatttt ttcaacaggt gtttcttttt tgaaaaaaga tttttttaca
      541 ttgatcttat ctgacaagat cgaacttaat ttactagcaa aaatcctata aaattcatct
      601 aaatagcgat aataaatccg attcagctga tcattaagat cgaagtatac aaaattattc
      661 tgtagtttat aaaaaaacgg cgaatgaaga tgtgttttca tatgaccaaa atataataat
      721 tctgaaattt ctaaaggtgt caattctttc agcatcgtta aatcagtaaa gtcgatccac
      781 ttcaattcat cgaatccacg cctgttacga gaagaggaaa agaaacgctg aatattttct
      841 gtaccacgga ttactttcag ccctgtatgg gattcatatt ctccagcaga agcagatgga
      901 tcaagcaaga gcaagttttg aggaaaatgc acgatactgt ttgcaaagtc agtagcagtc
      961 agcccttttg ttaaaacagc attacttgtg gtatcaatat gtacataaac tgactcagtc
     1021 atcatgttcc tcctcttatt tcctcttaat ctcttttatt ttacaacatt tgcattaaaa
     1081 aagcttgttt cttttatttt aaaattccat tacaaaatca cgttttcatt gaaaacactc
     1141 tcattttcaa ttaatttttg tgatttttgt atttttttat ttaaaggagg ttttatgaat
     1201 tgttttctta tggaatctac aaagtcgaat acgagactca tgaccttttt atgacgtact
     1261 ggtatacttg aagaaaaagg agagcgcgat ggagataaaa aaagtttact tttcacagaa
     1321 aatgtcgctg tattcgccta tccagcaagc aaaacaaccc cttccatttt ttcaaagtca
     1381 tcaagaaagt agagacgctt tttggcgttc tgcaaaaaag caatgtgctt ttaaagcagt
     1441 atcgaaaaaa tataccgtct attttactat tgctaaaagt agaggagatg ttatttttaa
     1501 taatctgttg attgaaggtg aaacttttga atggaaaaaa ttttttcggt atatggaagc
     1561 ttgcgctcgt ttttttatta aagaaaactg ttgtttttta tttcaatctc ctctatcaga
     1621 agaatggttg cgtatttttc ataaaaacgg ctatcaagga accacacaat taaataaaaa
     1681 gctggtctat catacagcac ttgttttagg tggaggagga gcgcacggtg cttatcagat
     1741 tggtgtgtgg caggcgctga aggaacatga tatcaacttt gagattatca caggtacctc
     1801 ggtaggtgcg ttgaacggcg cattgatttt acaaggagat atgaaaaaag ctgtgaattt
     1861 atggaaaaag ctgtcgacaa gacaagtgct tgcgttacca gaaatggctg cagttgaaga
     1921 ccttcgtgaa cgcttctatc gagaaagacg ccaaatgacg aaaacagcac taattgaagg
     1981 cggggtttct tctgctccat tggaaaagat ggtcaaagac aatttggatt tgtccttact
     2041 caaacataat cccaaaatac gtttatatac ggtgtctact aaactgccag aactagcgga
     2101 agtagtgact gatatccaac agacaaaaac agaagaaata ccagattgga tactcgcctc
     2161 tgcttcattt tatcccgcta tggcttatcg aaagatcgga aaaaataaat atgcagacgg
     2221 tgggtatcgc aacaaaatac ctattgatat tgcgattaac aaaggagcaa cagaggcatt
     2281 tgtcgtagat gtgcaagggc caggcccagc gaaaaaaatt cgtatgccag acatttttat
     2341 ccattggaaa tgtcaaacat tgtggacact aggcagcttt ctgctttttg atagccaaag
     2401 gaaccaatta aatttacaat taggctatct ggaaatgaaa aaacgattag gctattacta
     2461 tgggaactgg tatacatttc attctgttaa acctgcaaga acatactggc gaggattttt
     2521 gtcttactta acaaaagaaa ttcagttaga attatctttt ttcaaaagca taaaattttg
     2581 gcaaaaactg cgtaatttat ataagaacag ggtcgtacca gagacatgcg gattggcgat
     2641 gctagaactt ttagcaaaaa aacatttttt actgcccaat gaaatctatc aagtagacat
     2701 gatgattcaa atgatctgcc aacaagatat aaaaagtatg ccggatgatt tattggcaca
     2761 aattggtcaa ttaagtactg aagaatggcg aaggtatcga aaataccagc aaaaaataca
     2821 aaatgagcgc acgaaaactg tttattttga ttatctgcta caaggaaaac gcaaggatcg
     2881 tttgcagcat gaattgctta agcaaccagt tgacacatta ctgatcctat atttatatta
     2941 tctcaaggag gaacaaccat ggcacaagaa ttttcatatg aaatcgtaga agaaatcgct
     3001 atattgtcag aaaacaacaa ggggtggcgt aaagaactga acctagtcag ctggaatggt
     3061 cgcccgccaa aattcgatct tcgagattgg gcgccagacc atgaaaaaat ggggaaaggc
     3121 ctgacattga cgaacgaaga gtttgaacaa ctgcaaaaag caatagaaaa tatgtaatga
     3181 ggaaggaccc tgtcgaatga aaagtatgac tggttttggc aaagccatcc gcgaaacaaa
     3241 agcgtatcag ttagatattg aaataaaaag tgtcaaccag cgttttctag atgttcaaat
     3301 acgaagtcct aaaatcctga actttgttga aaacgatttt cgtcagctta ttaaacagca
     3361 gttaagccgc ggtcgaatcg aagtatttgt gaatctagct tatattggca aaaacgaaaa
     3421 acagatcgtc atcaactggg aattgattga ttcacttatc actcaattga cagacggaat
     3481 tcaacaacga tacggtagtc aaaatcaagt gtcaattagt cggatggcgg aacgcttcgt
     3541 gctggacgaa aacttcgtaa cggtagaaga aaaaccggaa gagagcatgg aagaattggc
     3601 acagttagct ctagatacat tgaaaagcgc acttgattct attgaggcga gtcgagaaaa
     3661 agaaggtcaa gctttagctt tagtgttgaa aaagaatact gaagaattca aagaagtact
     3721 aaaaaaactc gatagttttg tagaaatcta tgaaaaggaa tttcaaataa ggtatcaaaa
     3781 aaagctggag gaatttcttg gagcgaaagt cgatgagcaa cggttgttga cggagctagc
     3841 catcttgttg gaacgcggag atattcacga ggaactggat cgtctggcga tccatgtaca
     3901 aaaactagat gaacttatcg aagcacaatg tcctgtaggt cgggaattag atttcctgat
     3961 ccaagaaatg aatcgggaaa tcaacacgat cggttccaaa tcaaatgcaa tcgaaattaa
     4021 aaatcaagtc gtccagtcta agacgatctt agaaaaaatc agagaacaag tacaaaatat
     4081 tgaatgacga aagaggtaga gataatgaaa tattatgacg taacgttcca cgaattaagt
     4141 ggaaaaactg tggttaaacg ggatatccct tctgaaaaaa acggctttga cgtatggaaa
     4201 gatgcctgtg cagactataa tgagaacgaa ctgtttattt tgatcaacga cggtgcttac
     4261 gtgacgatga atcggaaatt tattgttcga attgacacag aagaggtaga agatccgaca
     4321 gaaaaagcac gttctcgaaa agatgagatc atgggtgtag tgaatacttt gtccaatatg
     4381 ggcttttagc aaggatgctg aacaaagaaa tacaataaat aaacagaatt ggatttcttc
     4441 gcttagcttc tttgctctag gaatacattt aaaggttgtg acaaaattcg tgtcacaatc
     4501 tttttttatt ttgaataagt gatgttcaaa aaccattttc tcggtattaa gccaaattta
     4561 tgcaaaaatg tgagaaacta ttttcacaaa atttttcttc atactcgaaa ctaatcggct
     4621 tcttcacgac ctcttataca cggcgttcaa aagcttgcat ctgcgataat aaccccaacc
     4681 aaacgaaaaa catgagaagc tgtttatgtt tggctgttct tattacttga tgcaggacag
     4741 cttttttacg acctcttggt acagggtagc ttttttacca atttctagct ataattaaag
     4801 ataaccttga aagttgcaga aaaaaagtgc aaaataaacg ataagtacaa aaagactagt
     4861 tgaaaggacg tcgtcatgtc agagcgtgga ttattaatcg tgttgtctgg tccatccggt
     4921 gtaggaaaag gcacagtacg aaaagcaatt tttgagagtg aggataatga ttttcagtat
     4981 tcgatctcaa tgactacccg taaaatgcgt gaaggggagg tcgaaggcgt tgattatttc
     5041 ttccgaagca aagaagagtt tgaatcaatg atcgaagctg gagagatgct ggaatacgca
     5101 gaatatgtcg ggaattatta tggaactcct ttgtcatatg tcaacaagac attggatgaa
     5161 ggaaaagatg ttttcttgga gattgaagtc caaggagcaa aacaagtcaa agaaaaagtg
     5221 cccgatggtg tattcatctt tttgactccg ccagatttag cggaattaaa atcacggatc
     5281 gtaggccgag gaacagatgc agatgaagta atcgaaaaac gaatgaaagt tgcaaaagaa
     5341 gaaatcgaaa tgatggctct ttacgactat gctgttgtaa atgatgaagt gccgctagca
     5401 gttgaacgaa tcaaaaacat tattgccagt gaacattttc gagtagatcg cgtaatcggt
     5461 aaatatatta aaatgttaaa ggagatgtag tcttatgatg ttaaaacctt caattgactc
     5521 actattagat cgtgtaaatt caaaatattc tctagtgatt ttagcaagta aacgcgcgca
     5581 tgaattggat gcaagtgcac agcctactct agattctttt gattcagtaa aaagcgtcgg
     5641 tcaagcttta gaagaaatcg atgcaggaaa tgtagtcaat gatccacatc ctgaattaaa
     5701 acgtgaacgt ttgaagatgg aagaagagga acgtcaagca caaaaagagc gtgaacaaca
     5761 cgaattggaa tcacgtatcc gtgaagagca aaaaatgtaa taaagaaaaa tagagcgaac
     5821 atctaaaaag aaaagcaaac ccagctgttt ccttttcaaa cattcgccac ttattgtctg
     5881 gtagaaaagg ctgtgtctga actttttgac acagttcttt tttttcttat ctgctgttaa
     5941 ttttttgtta ggatttggca gaagataaga caaatccatc gatctctagt aaaataggca
     6001 aggaactttt tgtcgcttga taagaaaaga caaaaaaagg aggaaacgaa ccatgacatt
     6061 aacagctgaa gtcattgtgg acgtacctac tatgcagacc gatcagccat tcacttattt
     6121 ggttccctct gaaatggaaa cagctttgca agtcgggatg cgagtagaag tcccttttgg
     6181 taatggcaat cgtcatgtcc aaggatttgt tatggctatc caaaaatcag aagaatcagc
     6241 taatccatct ttgaaggcag ttattcgttt gctagacctt gctccggtgg tcaatgaaga
     6301 attactttca ttagctgatt atatgaaaaa aattacttac gcattcaaaa tcacttgtct
     6361 acaaacgatg cttccgagtg tgatgaaagc agaatatgat aaattgatct atcctttggc
     6421 agacacacca gaagttcagg tattgtttga tcagcgagaa gtgatttcct ggaaggaagc
     6481 agaagaagaa ggcagccttt ctcaattgat tcgctggcgc caagagcaat tagtagatat
     6541 caaatatgaa gtccatacac gaaataaagt aaaaacgatt cgtttggtcc gttctttgtt
     6601 aactgaaaag caaatcgaag aagaatgggc aaaattacgg caaaatgcca agaaacaaaa
     6661 agaacttctt ttgtgtttat ctgaactgag ccaagaagaa ccaattgctt atttcaaaaa
     6721 taaaggaatc agtactgctg tcttgaatca aggaaaagaa aagggctggc tggagtttat
     6781 agaatcagaa cgttatcgcg acccttataa agaccgagta tttgaccaaa cgacggcatt
     6841 ggaactgaat gcagaacaaa aaaatgctgt cgaacaaatc atcacagcag gtcagcagca
     6901 aaaagatcag gtctttttgc tggagggaat cactggcagc gggaaaacag aagtatatct
     6961 tcaggcaatc gctgatgttt tgtcagaaaa taaaacggct attatgttag tgcctgaaat
     7021 cgcattgact ccgcaaatgg tcgagcgatt caaaggacgc ttcggagaat cagttgcggt
     7081 cttacatagc ggactttccc aaggtgaaaa atatgatgaa tggcgcaaga ttgagcggga
     7141 agaagcgcaa gtagtagtag gcgcacgatc tgctattttt gccccgctga aaaatatcgg
     7201 gctgatcatt atcgatgaag aacatgaatc aagttacaaa caagatgaga caccgcgtta
     7261 tcatgcgaga gatctagcaa tttggcgcag taaatatcat cattgcccaa tagttctagg
     7321 aagcgcgacg ccctctttag aatcaagagc acgagctcaa aaaggcgttt atcagttatt
     7381 gcagttaaac caccgagcca aagcagctgc acagcttcca gctattgaga tcgtagatat
     7441 gcgtgaagag tttcagaatc atcggacctc tactttttct gctaatttgc aggaaaaaat
     7501 acaaaatcga ttagacaaaa aagaacaaac tgtcctactg ctcaatcgtc gaggatattc
     7561 gtcttttgtg atgtgtaggg actgtggatt tgttcttcca tgtcctaatt gcgatatctc
     7621 tcttacactg catatggata cacgttcaat gcgctgccat tattgcggac atgaagaacc
     7681 tattcccaat cgctgtccta attgtggcgg caataaaatc cgctactatg gaacaggtac
     7741 tcaaaaagta gaagaggaac tccgagaact ttatccgcaa gctaggattt tgcgtatgga
     7801 tgtagatacc actcgaagaa aaggggcaca cgaacagatt ttacaaaaat tcggtgcaaa
     7861 agaagcagat atattattag ggacacaaat gattgctaaa ggtttggact ttccagaagt
     7921 gacattagtt ggggtgttga atgctgatac ctccctgaat ttaccggatt ttcgttctag
     7981 tgagcataca ttccaattgc ttacccaagt ttcaggacga gcagggcgag cggaaaaagc
     8041 aggcgaagtc gtgatccaaa cattcaatcc tcaacattac gccatagaat tggctaaaaa
     8101 acaaaattat gagcagtttt atcagcagga aatgcatgta cggcatcgtg gaggctatcc
     8161 tccttattac tttactgtga aaataaccgc cagccatcct gaagaacaag tagcggcaaa
     8221 gaaaatcttt cagattgcca atcagctaaa agaagtgtta agccctcaaa gcttgctatt
     8281 agggccaacg cccagcatga ttttgagagt gaaaaaccga tattattatc aactaatcat
     8341 caaatataaa catgaaccga atcttcctca tgttttggat gaaattttga atggaagcca
     8401 gaaagaacag cgacaaggtc tttttgtggc aattgacaac gaaccattaa actttattta
     8461 agaaagggcc aaattatgcg ctatcctata ttgatccacc ctaatgataa attaaaaaga
     8521 actgctcagc caatcgatgt aatcacggac gagacaatcg ctttattaga caatttatat
     8581 gagacaatga ttgcgaatga cggaataggg atcgctgctc ctcaagtagg acaaaacaag
     8641 agaattgctg tgatcgaagt agatgaaggc gagaaatttg aactgattaa cccagaaatc
     8701 atcgaagcaa aaggtgaaag ccttgacgta gaaggttgtc tcagtattcc gcatgtctat
     8761 ggaacggtca agcgagcaga tgaagtgacc gtgcgttatt atgatcgaga cggagaagag
     8821 atagaagtga cggcttttgg ctatttagcc cgtgccttcc agcatgaaat cgatcactta
     8881 gacggtatct tgttcattga gaaaatgata cagcagatcc cggaagaaga acttgaagaa
     8941 tatatggagg aacatcttga tgactaagct agtatttatg ggcacacctg ctttttctgt
     9001 gccgattctt gaagggctga tagaatcagg ttacgagatc caggcagtgg taacacagcc
     9061 cgaccgtcca gttgggcgga aacgagtaat tacgccgaca ccggtaaaaa aagcggctct
     9121 gaagcacggt atccgtgtgc tgcagccaga gaaaatctcc ggttcgccag aaatggaaga
     9181 aatcattgaa ttggtgcctg atgtgatcgt cactgcggca tttggccaat tcttgcctga
     9241 aaagttattg caagtaccaa aattaggggc aatcaatgtc catgcttctt tacttcctaa
     9301 atatcgggga ggtgcgcctg ttcattatgc catcatgaat ggggagaaag aaactggtgt
     9361 aacgatcatg gaaatgatca aaaaaatgga tgcaggcgga atctatgcgc aagaaagcat
     9421 accaatcact aaacaagatg atgtagggac gatgtttgaa aagcttagcc ttttaggaag
     9481 aaagctattg ctagaaacat tgcccaatat tttggatgga caaaaaccag tacctcaaga
     9541 cgagtcagaa gcaacttttt cgccaaacat cacacgggaa caagaagcaa tcgattggca
     9601 taaaactgca gaagaaattg acaaccaagt acgcggaatg cgtccttggc caattgcatt
     9661 cacgacctat gagggcatac gctggaaatt attatcggtt gaagtattgg cagaaactac
     9721 agacaaagca cctggtacga tcatccggaa agacaaaaaa aatctatgga ttgcttgcgg
     9781 taaacagacc gtcttagcca tcaatgaatt acagccagct ggtaaaggaa aacaggccgt
     9841 acatgatttc cttaacggaa gcggtcagca agttcagatt ggtcagcagg tgaaataatg
     9901 aaaaaaatcc ctaaaaaaat gaaaaaatca gtacgatata tggcattact gacattagag
     9961 cgagtgaaca agggtggcgc ctactcgaat cttttgttga atgagatgat caaacaaagc
    10021 gagctaaatc aaaaagatgt gggtttattt acagaattga tctatggtac gattagccat
    10081 cagcgactat tggaatttta cgttgcacca ttgatcgcta aagcaaaaaa agtggatgac
    10141 tgggtcaaga tgcttcttta tctttctgta taccaattag aatttttaga taaagtccct
    10201 gcacatgcta ttttaaacga ggcggtcgaa atcgcaaaag taaaaggaaa tcctgggaca
    10261 gggaaatttg taaatggtgt cttgaggaat tatcagcgtc aaggagcacc agatctgcaa
    10321 ggcattgctg atcctatcga aagactttct gtcaaaatca gcctgcctct atggatgacg
    10381 aaacgactgg tggatcaaat cggatacgaa gaaactgaaa agctcggttt atcgctatat
    10441 cagcctagcc atgctagtgc ccgagtagat acacgccgac tttccagaga tcaggccatc
    10501 actgttttgc aagaagaaga gatcacagct gaaaaaagcc aagtcagtcc atacggtata
    10561 gtagcgaaaa aagggcattt agcttctagc tcattgttcc acgatggcgt catgacgatc
    10621 caagatgaaa gttcgatgct tgtagcgccg tctatgcaaa tcgagcctga acatcatgtc
    10681 ttagatgcct gtgcagcacc cggaggtaag acgacgcata ttgcttcttt tttagatccg
    10741 tcatgcggtg gagaagtggt cgctttagat gtacacgaac acaaagtcaa actcattgaa
    10801 gataatgcag cacgtctagg tgtctcttct gctgtctacg ctcaaaagat ggatgctaga
    10861 gaagtcagta aacagttcga agcagagcag tttgatcgga ttttagtaga cgcgccttgt
    10921 tcaggtcttg ggctgcttcg gcgaaaacca gatattcgtt ataaaaaaca gccggatgaa
    10981 ttagcgaatt taccaaaaat ccaattggaa attttagaaa gctgcgcacc aactttaaag
    11041 tcttccggta ttctgactta tagcacttgt acgatcttaa aagaagaaaa ccaagacgtt
    11101 gtttctgctt tcttggaaag acaccctgat tttgagagga ttgatgtttt gaccaatcct
    11161 atgctacaat catcaatcga agagaaaatg ttgactttgt atccgcatca gttttacaca
    11221 gatggatttt tcatttgttg tttgcgcaaa aagtaatgag gtgaaaaaat gcagattgaa
    11281 tatcaatcag atgtaggaag acgacgtaac acaaatcaag actatgccag tgtatttacc
    11341 agccgttcag gtctcaagct tgctgtatta gcagacggga tgggtggtca tcgtgccgga
    11401 gacattgcca gtcagatggc ggtaacgaat ctaggcgaag cttgggaaaa acaagaagct
    11461 gttgacgatg aaaaaatcgc ccaatggttc attcaatcga ttcaagaaga aaatatgctg
    11521 atttatcagc gtggacaaga acagccggaa tataacggta tgggaacaac aatcgtagcg
    11581 gccgctctgt cagatgactg gttcacgatt gccaatgttg gggatagcag agcttatttg
    11641 attcgtgaag ataaaatcat gcaattgacg gaggatcatt ctttagtcaa tgaactagtc
    11701 aaatcaggag aaatcagcga agaaatggca gtgaaccatc caaggaaaaa tattttaaca
    11761 cgttctgtcg gcatgcctgg aacagtcgaa gtagatgttt ctactcatct ttggcaacta
    11821 aaagatcgac tgctgttatg ttcagatggc ttgacgaaca tgctgtctga agaagaaata
    11881 ggaacgatca tcaatcaaga aggcccattg tctcataaag taactgagct gattgatcgt
    11941 gccaatgaag caggcggagc ggataatatc accgttcttc ttatcgaata taaggaggac
    12001 agtgtatgat cgagttgggc aaaaaattaa atggccgtta tcaaatcact ggaaatatcg
    12061 gtagcggtgg tatggcaaat gtatttttgg cgcacgattt aatcttggat cgtgatgtag
    12121 cagttaaagt cttacgattt gactttcaaa atgaccagac tgcgattcga cgatttcaga
    12181 gagaagcttt agcagcaaca gaactcgttc atccaaacat tgttagtgtt tacgatgttg
    12241 gtgaagaaga caacatgcag tatctggtga tggaatacgt caaaggaatg gacttgaaac
    12301 gatatatcca aacacattat cctgttcctt atgaaacagc agtaaatatt atgcagcaga
    12361 tcctttctgc tatttcttta gctcataacc atcaaatcat ccaccgagat ttgaaacccc
    12421 aaaacgtact gatcgataat gaaggtgttg taaaaatcac ggatttcggg attgctatcg
    12481 ctttatctga aacatcgatc acgcagacga atacgatgct aggatctgtt cattatctgt
    12541 cccctgagca ggccagagga agtatggcaa cgaagcagtc agatatttat gctttaggga
    12601 tcatccttta tgagatgttg acgggtagcg taccgtttga tggtgaatct gctgtaacaa
    12661 ttgctttaaa acattttcaa gatgatcttc catctataaa agcacttgat ccaaatgtgc
    12721 cacaagcact ggaaaacgtg attttacggg caacggctaa agaacctgca gaccgttata
    12781 agtcagccga ggaaatgtct gatgatcttt ctacagtatt atcaccagct cgtgcaaacg
    12841 aagaaaaatg gcagcctcat gtgatggata atgaaacaaa agttatcaca ccccttacgg
    12901 aagatgcacc aatgcctgat tcattcaaat ctatgcctct gccaaaagac aagccagaaa
    12961 acgaaacctt accagaggag gaagaagttc tgcctgatcc taaaaagaaa ggacagaaaa
    13021 aatggtggct gatcctatta gctattcttg ctgttttagg aatcggaaca gctgtattct
    13081 ttgcttctgg cgggcgagga gaagttgttg ttcctgatgt ttctgatctt tctgaagctt
    13141 ctgctagaga aacactcgca aaagcgaaat tagaagtagc aacaaaaaca gaagaaattg
    13201 cagatgacaa aatcgaagaa ggtaatgtag tgaagacaga cccggcagcg ggaacgacag
    13261 tcaagcaaaa acgcgaagtc actctgtata ttagtagcgg cacgaaaaaa atcaaattag
    13321 atgattacag tggtaaaagt tatgaagatg ccgaagcaag tttgaaagaa ttagggtttt
    13381 ctgctgactt gattcaaaaa gaagaggaat tcagttcaga ggtagaaagc ggaatgatca
    13441 tttcgcaatc tccatcagaa gatacagaag tcgatcctaa aacagacacg attactttca
    13501 cagtcagcaa aggaccagaa acagtgactt tgagtagtca tgtaggagaa aactacgaaa
    13561 ctgttcgtaa ttggcttgtt acacaaggat tcaatatcaa taatattagt gctacttatg
    13621 actatagcga cactgtacca tcaggttcga tcatcagtca ggatccagcc tcgggtgaag
    13681 ttgtagcaga agaaacttac atcaattttg tcgtaagcca aggaacagag cctaaattga
    13741 atgatatctc cggctataca aaaagcgaag cacaaagtta tttagctagt gtcggtgcag
    13801 aatatatcgg gcatgagact tccgaatatt caaacacggt ggataaagat aaagtgattc
    13861 gtacagtacc aggggcagga acgacaatta ccaaaggaat ggttgtgaac gtaatttact
    13921 ctaaaggacc agatccagcg tcttctagtt ctgaaaaaga ctcttcagac agttctagca
    13981 gctcaagtag ctccagtagc acaagcaact cttcaaaaga agaatcttcc agctccacaa
    14041 gttcatcagc tagcacctca gaaagttcaa aataagtgct gaataaaata tatcagaagg
    14101 gaatgcgaca ttgatttgtt gcattctctt ttttgtgttt ctatctcttt tgatcaattt
    14161 tcaagccata tactttgaga agtttgcatg gaataacacc tactttcctc ttcgtatggt
    14221 aaaataaaca aaaacggagg tggcacttat caaaggacaa atcagaaaag caatcagcgg
    14281 tttttactat gtatacgcaa acggagagac ctatcaaaca agaggaagag gaaatttccg
    14341 gaatcggaaa atcacgccgc ttgtcggaga tcaggtgatc tttgagagtg aaaatcaaac
    14401 agacggctat cttctggaaa tcttgccgag aaaaaatcaa ttagttcgcc caccagtcac
    14461 aaatgttgat cttggaatca ttgtcacaag tatcgtagag cctgcatttt cttataatct
    14521 acttgaccgc tttctagtta ccttggaata cgagtcgatc gaaccgatta tttttttgac
    14581 aaagaccgac ttgtcagacg acccagaaaa aatcgaagag atcaagcaaa cctatactaa
    14641 aataggctat ccggtgattg tacccaatca tacgggtgat acgacagaac tgatccgtta
    14701 cttcccagaa cggctatcgg tctttatggg tcagtctgga gcaggaaaat cgacgctact
    14761 gaatcaaata tcaccggaac tgaatttagc aacaggagag atttctgatg cacttggaag
    14821 aggacggcat acaacacgtc atgtggaact gattcctatc tatggcgggt tagtagcaga
    14881 tacaccagga tttagctcga ttgacttttt gacaattgaa gcaggagaac tgccgagaca
    14941 atttcctgaa tttgtagaag cttctgtcca ttgcaaattt agagagtgca tgcatgctaa
    15001 agaacctggc tgcgaagtaa aacatagagt agaaacaggt ggtatcgcac agacacgtta
    15061 cgacaattat ttgcaattct tacaagaaat cgaaaaaaga aaaccaatgt atgcaaaaaa
    15121 agaaggtaaa cgaaaatagg aggaaacaag aatgaagata gcaccatcca ttttgagtgc
    15181 agattttgcc aatttacaaa gagacattga gttagtggaa aaaggaggcg cagattacat
    15241 ccacgtagat gtaatggatg gccgatttgt cccaaatatc acattagggc caaatattgt
    15301 tcaggcaatc cgtcctgtta ctaaattacc gttagacgtc catctgatga tcgttgatcc
    15361 agaaaactac attccagcat ttgcaaaagc tggagcagat atcattactg tccacgtcga
    15421 agcaactcct catattcatc gggcacttca aatgacaaaa agcttaggag ttaaagctgg
    15481 agtagttatc aatccaggaa caccagtctc catgatcaaa catgttttgc ctttggctga
    15541 tcaagtacta gtcatgactg tcaatcctgg gttcggcgga caaagcttta ttgaagaaac
    15601 agtagaaaaa attacggaac tcgctgatct acgtagagag aacaattgga cttatgcaat
    15661 cgaagtagat ggcggaatcg ttccagaaac agcaaaaatc tgtaaagatg caggggcgga
    15721 tgtcttcgtt gcaggatcat atatctatgg agccgaaaat ccagtcggac aaatcgaacg
    15781 attaaaagag gcattagact aaatgaaaat tttattagct gctggaggta atccgcaaaa
    15841 ctggccgcag tctctgctgt ccaaatacga tgcctatgtc gggatagacc gtggtgcgct
    15901 gtacctgctt caagcaggct acccagtaga tctggcagtg ggtgattttg attcattgtc
    15961 gaacgaagag cagaaggaag tatttgcaaa agccaaagag tatacccgtt cccctgcaga
    16021 aaaagacgat acagatacac agttaggtat cttaaaaaca tttgaacgtt acccgcaagc
    16081 ggaagtcact ttgattggag ctacgggcgg aagattggat catcttttag ccaatctctg
    16141 gttaggtatg gaacctcgct tcaaaccctt tgcccatcag cttattatca gagattgtca
    16201 aaattatttg tcttattatt tgcctggaga gcatatagta agacagatac cagatatgaa
    16261 gtatttagct tattgctgct tgactcccgt ctcgaatctt acattaaaag gcagcaagta
    16321 tgtattggaa aataaagaag tagaatatcc gacatcttat gcaagtaacg aatttctttc
    16381 agataccgca gaattttctt tttcagatgg tatgattgca gttattcaaa gcaaagattg
    16441 atccataaac aaataaaaaa atttgtcttt caggctaaaa atgacagaat ctattatttg
    16501 ctaaaaaaaa gcttaagagg agcaacttac cttttgtttc acggcattta gtgataaaat
    16561 tgaacacaag agtctaatta attcgaggtg tctttgtgaa gaagttcaat cctaataaaa
    16621 atattattat taccttggtt attgttatca tcgtggtgac gatactaagt gtgaccgctg
    16681 cgcagcgagc gaatgaagga aagcccaatt tcttccaatc catcgttaat gacagtgttg
    16741 caatggttga taaaacaatc tctgccccag tacggtgggt acgaaatgga gtagattctg
    16801 tccataatct tttttcaact tatgccgaaa atgagcggct aaaagaaaaa atcgatagct
    16861 atgatgacgt ttcacagcaa aacaagaatt acgagagaga aatcgaagcg ttgaaaaaag
    16921 aacttgagtt gaatcagacg ctgactagtt acgaaaaagt aacggcaaat gtcattactc
    16981 gttcgcctga cagttggcag gacatgctga tcgtagacaa gggttctaaa gacggtatcg
    17041 aagcaaatat ggcagtcatg tcgcaaaaag gattgattgg ccgagtgatc gaggtcaata
    17101 cggcttcgtc taaaatcgaa ttactgtcat cctctaatga aagctccaat cattttccag
    17161 tacgggtatc ttcggctaat ggcgaagcgt ttggtttgct taaaaactat gatgaaaagc
    17221 tccatgcctt agtggtgacc caattaactg gtgatacgga tatcaaagaa ggggatgttg
    17281 tccagacatc cggtcttgga gggaattctc cagctaactt gccgatcggt acggttatta
    17341 aaacgaaacc agatagttat gggctggatc gggaagttta tgtgaaacct tatgcagaaa
    17401 tgtatgacgt gtcagttgtg acgattgtcc aacggctagc ggaggattag tccatgttga
    17461 agaaagaaac aatgaagtac tatctgccaa tcgttttgtt ctttttgatg ttgatagatg
    17521 gtcatttaac aagaatgcta ggggagtggt cgaaaggcac ctatatgtca aatgcccact
    17581 ttctgatatt ggcattatta tgttgcagta tggcgtttga aaaacgttat ttactgatta
    17641 ccacgattgt tctcggggct atctatgacg cttactatat tggcgttatc ggtatctatg
    17701 cagtagctct ccctttaatt gtatggttga tgtatgtaat gaaagacgtt atccatgtca
    17761 acatctttac tgaatttttc agtatgatca tctttgtcac gggttatgaa ttgtttacga
    17821 tggtggtcca gttgattttt aaattagcag tagtaaataa cacgtatttt attacaaggt
    17881 ttttaggacc tacactgctg ttgaacatga ttatatttgt attattcatt tttcccttta
    17941 agaaattatt cagtgatgaa taatttcttt ttttattttt aggtcgaaag cgaaaaagaa
    18001 tcgttgttat cttaagaaat gctagactta acgcggcttt ttcatgatca ttttctgaaa
    18061 cgaacagttt tgtcattttt aaaagttgtt ttgaaacatt tttgtaacat aactattata
    18121 tcgttgacac actgctatgg tacaattttt atatcgttaa gaaagactta aatatattta
    18181 gatatttatt aaattaagcc agtcggagga atgaagagtg aaaaagagtt taatatcagc
    18241 agtaatggta tgttcaatga ccttgactgc cgtagcatca ccgatcgctg ccgcggcgga
    18301 cgattttgat tctcagatac aacagcaaga tcaaaagatt gcagacttga aaaatcaaca
    18361 agcagatgca caatcacaaa tcgatgcctt agaaagccaa gtttctgaaa tcaacacaca
    18421 agcacaagac ctattagcaa aacaagatac attgcgtcaa gaatctgcac aattagtaaa
    18481 agacattgca gatttacaag aacgtattga aaaacgtgaa gatacaatcc aaaaacaagc
    18541 acgcgaagca caagtaagca acacaagctc aaactacatc gatgctgtat tgaatgctga
    18601 ttcattagca gatgctattg gacgcgttca agcaatgaca acgatggtaa aagcaaacaa
    18661 cgacttgatg gaacaacaaa aacaagataa aaaagctgta gaagacaaaa aagctgaaaa
    18721 cgatgctaaa ctaaaagaat tagctgaaaa ccaagctgct ttggaatctc aaaaaggcga
    18781 tcttttatct aaacaagctg atttgaacgt actgaaaact tcattagctg ctgaacaagc
    18841 aactgctgaa gacaagaaag ctgacttgaa ccgtcaaaaa gcagaagctg aagcagagca
    18901 agctcgtatt cgtgaacaac aacgtctagc agaacaagct cgtcaacaag ctgcacaaga
    18961 aaaagctgaa aaagaagcac gcgaacaagc agaggctgaa gcacaagcta ctcaagcttc
    19021 atctactgca caaagctcag caacagaaga atcatcagct acacaatctt caatgactga
    19081 agaatcatca tcagctacac aatcttcagc aacagaagaa tcaacaacac ctgaatcttc
    19141 aacagaagaa tcaacagcgc ctgaatcttc agcaacagaa gaatcaacaa cagcgcctga
    19201 atcttcagca acagaagaat caacaacagt gcctgaatct tcagcaacag aagaatcaac
    19261 aacagtgcct gaatcttcaa caacagaaga atcaacaaca cctgcgccta caacaccatc
    19321 aacagatcaa agtgttgata caggaaacgg cacaggaagt agtactccgg ctccaacgcc
    19381 aacaccaaca cctgaacaac caaaacctgt aacacctgct ccagctcctt ctggaagtgt
    19441 gaatggtgca gcaatcgtag cagaagctta caaatatatt ggtactccat atgtttgggg
    19501 cggtaaagat ccaagtggct ttgactgctc agggttcaca cgctatgttt acatgcaagt
    19561 aactggtcgt gacatcggtg gttggacagt tcctcaagaa tcagctggaa caaaaatttc
    19621 agtttctcaa gcaaaagctg gagacttgtt attctggggg tcacaaggcg gaacttacca
    19681 cgtagcgatt gctttaggcg gaggacaata tatccatgct cctcaaccag gcgaaagcgt
    19741 aaaagttggt tcagttcaat ggtttgcccc tgactttgct gtcagcatgt aagaatga
//
LOCUS       DAFLWZ010000049        19633 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000049 DAFLWZ010000000
VERSION     DAFLWZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.049"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1V38_001876"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1V38_001876"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBN1316425.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="L1V38_001877"
     CDS             complement(1172..1867)
                     /locus_tag="L1V38_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBN1316426.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="L1V38_001878"
     CDS             complement(1880..2596)
                     /locus_tag="L1V38_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBN1316427.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="L1V38_001879"
     CDS             2926..3534
                     /locus_tag="L1V38_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBN1316428.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="L1V38_001880"
     CDS             3859..4182
                     /locus_tag="L1V38_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1316429.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="L1V38_001881"
     CDS             4364..5734
                     /locus_tag="L1V38_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBN1316430.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="L1V38_001882"
     CDS             complement(5864..7165)
                     /locus_tag="L1V38_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1316431.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="L1V38_001883"
     CDS             complement(7519..9477)
                     /locus_tag="L1V38_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBN1316432.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="L1V38_001884"
     CDS             complement(9654..9920)
                     /locus_tag="L1V38_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1316433.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1V38_001885"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1V38_001885"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBN1316434.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1V38_001886"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1V38_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBN1316435.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="L1V38_001887"
     CDS             13264..13827
                     /locus_tag="L1V38_001887"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1316436.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="L1V38_001888"
     CDS             complement(14080..14601)
                     /locus_tag="L1V38_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBN1316437.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="L1V38_001889"
     CDS             complement(14604..15446)
                     /locus_tag="L1V38_001889"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBN1316438.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="L1V38_001890"
     CDS             complement(15439..16164)
                     /locus_tag="L1V38_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBN1316439.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="L1V38_001891"
     CDS             16340..16636
                     /locus_tag="L1V38_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316440.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="L1V38_001892"
     CDS             17204..18796
                     /locus_tag="L1V38_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1316441.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="L1V38_001893"
     CDS             18809..19549
                     /locus_tag="L1V38_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1316442.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3724 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaa
//
LOCUS       DAFLWZ010000050        19574 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000050 DAFLWZ010000000
VERSION     DAFLWZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.050"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(270..1766)
                     /gene="lysS"
                     /locus_tag="L1V38_001894"
     CDS             complement(270..1766)
                     /gene="lysS"
                     /locus_tag="L1V38_001894"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBN1316443.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="L1V38_001895"
     CDS             complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="L1V38_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBN1316444.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="L1V38_001896"
     CDS             complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="L1V38_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBN1316445.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3986..6097)
                     /gene="ftsH"
                     /locus_tag="L1V38_001897"
     CDS             complement(3986..6097)
                     /gene="ftsH"
                     /locus_tag="L1V38_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBN1316446.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="L1V38_001898"
     CDS             complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="L1V38_001898"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBN1316447.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="L1V38_001899"
     CDS             complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="L1V38_001899"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBN1316448.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8297..8767)
                     /locus_tag="L1V38_001900"
     CDS             complement(8297..8767)
                     /locus_tag="L1V38_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBN1316449.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8813..9238)
                     /locus_tag="L1V38_001901"
     CDS             complement(8813..9238)
                     /locus_tag="L1V38_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBN1316450.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9305..9574)
                     /locus_tag="L1V38_001902"
     CDS             complement(9305..9574)
                     /locus_tag="L1V38_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBN1316451.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9585..11180)
                     /locus_tag="L1V38_001903"
     CDS             complement(9585..11180)
                     /locus_tag="L1V38_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1316452.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="L1V38_001904"
     CDS             complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="L1V38_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBN1316453.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14733..15293)
                     /locus_tag="L1V38_001905"
     CDS             complement(14733..15293)
                     /locus_tag="L1V38_001905"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBN1316454.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15646..16620
                     /locus_tag="L1V38_001906"
     CDS             15646..16620
                     /locus_tag="L1V38_001906"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1316455.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16790..18190
                     /locus_tag="L1V38_001907"
     CDS             16790..18190
                     /locus_tag="L1V38_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBN1316456.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18268..18990)
                     /locus_tag="L1V38_001908"
     CDS             complement(18268..18990)
                     /locus_tag="L1V38_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1316457.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19069..19554)
                     /locus_tag="L1V38_001909"
     CDS             complement(19069..19554)
                     /locus_tag="L1V38_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1316458.1"
                     /translation="MKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLESWLPNQPF
                     KDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGVFPKLKIW
                     WLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVLFAAFKKR
                     L"
BASE COUNT         5328 a         4345 c         3495 g         6406 t
ORIGIN      
        1 ttttgttatg tttttgaata aatattttct tctgtctttt ggacaagtaa taatatacca
       61 actaaattta gcttggtcaa cgaatttttt gtattttttc aagttttttt caataaacga
      121 ttattcataa cttttctttc tttatcgttc gttttcgtct tctttaatgt ctagaatagt
      181 cggcattagc ttttgaactt tcgttattat ttattccttt ctacacagca aaagctgcct
      241 aaggaattcc ttagacagct tttattcgat tatctcattg ttgggaatag caaaacatcc
      301 cgaattgatt gtgcatcagt tagcaacatt actaatctgt cgatcccgat gcctagacca
      361 ccagttggcg gcataccgta ttctaaggct tccaagaagt cttcgtctac accgtgagct
      421 tcgtcatttc ctagttcacg ttctttttct tgcgcttcga atctttctct ttgatcaatt
      481 ggatcgttca gttctgtaaa ggcattagca aattcgcgcc ccactatgaa tagttcgaat
      541 cgatctgtga atcgaggatc ttctggattt ttcttcgcta aaggcgaaac ttcgactgga
      601 tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa caaatgtttc aaagaattca
      661 ttgataacat gtccgacacc catagcttcg gttacttcta cattgtgttt ttcggctaaa
      721 gctaatgctt cttccaatgt catttcttgc cagaagtcta caccagtttg ttctttgatt
      781 gcatctacca tatggatgcg tttaaagtca ctttctaagt cgacagcttg tccatcatat
      841 gtgatttttg ctgttcctag tactttttca gctgcgttac ggataatacc ttctgtcaga
      901 ttcattacat cattgaaatc agtatatgct gtgtatgctt ctaacatcgt aaattctgga
      961 ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc cgatttcata aactttttcc
     1021 attccgccaa caattagtcg ttttaaatga agttctagcg caatacgcaa atataaatca
     1081 atgtccagtg cattatgatg cgtgataaat gggcgtgcgg cagctccacc tgcctcattg
     1141 tgcaatactg gtgtttctac ttcaatatag ccattgccat ctaaatagcg acggatttcg
     1201 ctgataattt ggcttcgttt cataaatcgg tcaaagcttt cgcgattact gattaaatcc
     1261 aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc catggtattt atctggcagt
     1321 ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt tgatagaaac ttcgcctgtg
     1381 tctgttttca tgatttgtcc agttacacca aagaaatctc caaggtctgc atgtttgaat
     1441 acttcatagg cctcatcacc tacttggtct tttcttacat aaatttgaat ttggccttca
     1501 cgatcttgta gatgcgcaaa tccagctttc ccttttcctc ggcgagtcat catacgacca
     1561 gctacactag cggtcaatcc catttctgct agttcttctt ttgttcttgg atcaaatagt
     1621 tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt ttccaaatgg atcgattcca
     1681 tcttcacgca attgttccat tttttgacga cgtacaagca tttgatcatt taaatcttct
     1741 acttgatgtt gttgttcctg tgtcacaaaa gttcctccat tctcatgtta atctctttcc
     1801 tataatgcca atgaaacaca aaaaaagcaa gccgaacttg gaatttcggc ttgaaaattc
     1861 acgaaaaact tagaaatcac aacgtttgtt tcaatagtac tttttccgct ttttctacaa
     1921 attgatccag caggtcattg atttcttgct gtttttctgt ctgattgatt gctactttca
     1981 ctttcgctgc tcgaggaatc ccttttaaat aataagccgc atgtgttctg aattctctac
     2041 aagctacttt ttctcctttg agatctgcta agcgttgtaa atgaagttta gctgtagcaa
     2101 ttttttcggc tggtgttggt tcaggaatca gttcccctgt ttcgagataa tgctgtgtgc
     2161 ggtgaatcat ccatggattg cccagcgctg cacgaccaat catcacaccg tctgcaccga
     2221 catagtcaag catccatttt gcatcttctg gcgttttgac atccccgttc cccataaatg
     2281 gaatcgtcaa atgttttttc acttctttca atacttccca gtccgctttt ccttcataca
     2341 tctgaacccg tgtacgtcca tgcatagcga tggcacttgc tccagctgat tgtgctgcta
     2401 atgcattttc tacagcaaag acgtgctctt catcccaacc aatacgcatc ttgattgtta
     2461 ctgggatatt tactgctgaa gaaacagctt ggaccatttc gtatactttc tcaggatcta
     2521 aaagccattt tgctcctgct tctgctttga ttactttatt tactggacag cccatattga
     2581 tatctattat atcggcagct gtgttttctt cgacaaattg agcagcttca actagactat
     2641 ctttatttcc gccaaatatc tgtaaactta atggatgttc tgtttcttca atgtggagca
     2701 tctctaaagt ttttttgttt ctgaaatgaa taccttggtc actgatcatt tcacatacga
     2761 ctaagcccgc accaaattct ttgacagtga ctcgaaatgc tgaatttgtt attccagcca
     2821 tcggtgcaac aacgacacga ttagggattt ccacattgcc aattttccat gtgtgttcca
     2881 cttaaatccc tcctaaggct tctttcttca atccatctaa ttcttcttcg ctatacttgt
     2941 atttgttatt acagaaagaa caaaccgctt ctgcaccgtg atcttcgtct atcattgctt
     3001 ggatttcttc tgcacctaac gcgataattg cttctgcaaa tttttctttt gaacagtcac
     3061 atttgaattg aacaggcatt ttttccaaaa tgttcaattc ttctgtacca agcaatcctt
     3121 tcaatatttc ttctggtgtc tgtccttcat ctaagagggt agagattctt ggtgtcgttt
     3181 ttaattgttc ttcgatcttg ctgattgttt cttcatcggc acctggcatg atttggatca
     3241 tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac caatacactc agtccaacag
     3301 ctgaagggat ttgttctgag atagcaagat agtaagtaaa atcttcagcg atttctccag
     3361 aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc taagtctttt gtgacagtaa
     3421 acattccttg tgttccaact gctccccgca catcgatttt accttcacta tttagaggaa
     3481 gactgagatg cggatttttg atgtaacctt tcacatctcc ctttccattt gcatctacta
     3541 caattcctgt tgctggacca tcgccttgga ttcgaacagt tagtttgtct tctcctttga
     3601 gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc caaagcagct gaggaggtgt
     3661 gccaagtatc atgacgtctt tgtgcctccg ctacggtatt tgttgcttga acggcgtatg
     3721 ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata atctttcatt tgttatgtac
     3781 tcctttttcc gtttttaaac tcatagtgaa tcatactagc aactactgct tttttcaact
     3841 ttggaatgct tcttttaaaa ataattcaga atcatctaga aaacaggaca tcaccctatt
     3901 tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg ttccggtttt cgggagtcat
     3961 atcagatcaa ttgacctata tttttttatt tgtattgatc gtctgaatga ttatcttctg
     4021 attgttgaga atctgaatca tgttctgctt tattttcctc attcagttca tgttttgctt
     4081 cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc tttttcttcc aaagcacgtt
     4141 ttgcttcttc aaaagttttc gcttcttttt cgcttggata atcatttgac tcagtacctt
     4201 caggcatcac accgtgttca aacaatgact tgattgcttt ggcatccaat gtttcgaatt
     4261 ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg agcttcgatg atttctcgag
     4321 ctttatcatg agcttccatc aagatttttc gtacttcttg atcaatctcg aaagcgactt
     4381 gttccgagta agcttttgtt tgaccatagt cgcggccaac aaacacttga tggtttcctt
     4441 catattgaac aggacctaaa cgatcactca ttccatattc tgttaccatg cttcgtgcta
     4501 gagctgtcgc ttgctcaaag tcattggaag caccagttga ttggacattg aagatgattt
     4561 cttcagctgt acgtccacca agtaagccta cgatttgttc aaacatatct tctttcgtca
     4621 tcaagaactg atcttctttt ggtaaagcga tcatatatcc gccggcgcgt ccgcgaggga
     4681 tgatcgttac tttgtggacg acccgagcgc gactcaatac taatccgaca atcgtatgac
     4741 cagcttcgtg ataagcaacc atttcgcgtt cttttttgct gattacgcga tcttttttag
     4801 ctggacctgc aatcacgcga tcttccgctt catcgatatc agaagcatcg attttctttt
     4861 tatttcttct agcagctact aacgctgctt cattcaagac attttctaaa tctgctccgg
     4921 caaaacctgg tgtctgttga gccacaactt tcaagtcaac gtcatctgcc atcggtttat
     4981 tccgtgcatg gactcgcaag attgcttcac gaccttttac atctggacgt ccaactaaaa
     5041 tctggcggtc aaaacggcct ggacgtagta acgctgggtc tagtacatca gaacggttgg
     5101 ttgcagcaat gacgattact ccttcatttc cgtcgaagcc atccatttct acaagcaatt
     5161 ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat accggcacca cgttgacgac
     5221 ctaccgcatc aatttcatca atgaaaatga tagctggtgc gtttttcttc gctgtttcaa
     5281 acaaatcacg aacacgactt gctccaacac cgacaaacat ttctacgaaa tcagaacccg
     5341 agatcgagta aaacggtact ccagcttctc cggcaacagc ttttgctaat aaggttttac
     5401 ctgttcctgg aggtccttct aaaagtacac ctgccgggat acgggcacct aattcaacaa
     5461 atcggcgagg atctttcaga aattcaacaa cttcaactag ttcttgtttt tcttcttccg
     5521 cacccgctac atcagaaaaa cgtacgcgat tagctttttt gtctgcttct ttggcttttg
     5581 atttaccaaa gttcatgaca cggccgccac cgccaccgcc gccgccttgt tgtcccatca
     5641 tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa gctaagcaat agggaaaccc
     5701 atataccgct gcttgattct tcttttactg ttgtagcaac tttgttttct tttgccagtt
     5761 ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat tgttgtgaaa tgggtagtag
     5821 tcgtatctgt tgaacctaag atagctaacc caccgctgtt agcgacggtc tgctgttctt
     5881 tgtattcacc agtgatctta tatacaccat ttgcaggctg cacttcaaat tctttgatct
     5941 tgcctgcttg tagttgttct gtgaattttg agtactcgat atctgacgat cgctggccgt
     6001 tattaccaaa aatgaaataa acgaccatta ccatcgctaa gattacgagg acataataca
     6061 aggcattttt catcatgccg ttgttctttt tgttcatagt tgccctccct aagcgtcaat
     6121 ttaatttaac agttttttat caatcctgac cattctattg taccataatt taattgagat
     6181 acagcattaa tttgattgat aaacactagg tttcaataca ccgatgtacg gaaggttacg
     6241 atatgcttct gcataatcca agccataacc gaccacaaat tcatttggta cgttgaagcc
     6301 aacataatct gcttcgatat ttactactct tccttcaggt ttgtcaagta gtgtaacaat
     6361 tttgactgat tttgctttgc ggtatttgaa aagatccact aaataagcaa gtgttcttcc
     6421 gctgtcaatg atatcttcaa cgatcaacag atcgcgacct tctacattcg tatctaagtc
     6481 tttgacgatt tttacttccc ctgacgagac tgttgcattc ccgtagcttg aaacatccat
     6541 gaaatccaat tccaaatacg tatcgataga acgaacgata tctgccatga atggtaccgc
     6601 tccttttaag acacctacta ctaggggatt ggtgttttgg taaatttctg ttaactcttt
     6661 gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag atcaaaattc tctcaatatc
     6721 cttttccaac atcaggttct ccttccaatt gcttcttttt gatatttgta aagaagtatg
     6781 tagtgtattt tatcagtttc ttcacgaata ctcaaatatg aaaaggcaaa aggtatcaag
     6841 ctatatatat ttcttttggc atctgtaatg atccaagcat gctgcctttg tgaattaggt
     6901 actttctgat cgataaaata tctagatact ttttttgtga gattctctgt taatttaatg
     6961 cggtctcctg cttttctttt ttcgacatac agttgcacat cagcaggaat ccaaatgtca
     7021 tgagaaaata gagaccatga atctgttgct ttgatgtccc ctgcattttc aggtttgacc
     7081 agaccaatcc attctgtttc attcaaatat attccttgtt ctggaatcag caacaagcgc
     7141 tggtcttctg tctggctagt tgcttgtttt tcttttttag agagtacaac aaaatgatac
     7201 tctcttttca gtatccaatt attgccaata ctgagttgcc attggctttt tttctgttgc
     7261 cactggtcta aaatcgactc catttgttgt tctttcaaaa taattcctgt ttttgagaat
     7321 gctttgtcga aaaaggagta aaaaaaatag tatcgttcag catctgtcat ttcttcaatc
     7381 atttctgcag aaaatcgaaa ttgttcctcc cactgttcga cttccttttc gatcaactgt
     7441 cccatatatt tttgaatgac ttggtctgcc cattggatct gttgcgaaaa ttgctggaaa
     7501 tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa ctaccaaatg acgaagccga
     7561 tttctctgga tatctaacaa ttggtttgtc tgatcctcaa agtaaacaag ctgcgattcc
     7621 gctgcataag tatataggtc ttctttgcta aaactcagca acggacgaat cagtctgccc
     7681 gtagcaaatg gttgtacttc tttgattcca gaaaaagtat ttaactgtcc cccacgaacg
     7741 attttcatta acaccgtctc gatttgatca tctccgtgat gagcagtcat caacgtgtca
     7801 tattgtcctt cttccatcac gcgagtgaat tcttgataac gaaagttacg agcttctgtt
     7861 tctatggcgg atttggctgg atcttcccaa atacttacat ataaagggag attcttctct
     7921 tcacaatatg agcgaagata ggcagcttct tctgctgatt cttctcttaa ttggtgattg
     7981 atgtggacga tacctaaaga aaaaccgatt tggcgttgca cttgtaaaag taaatggagc
     8041 aaaaccatcg aatcaacacc acctgatacc gctgctaaaa ttctcgatcc ttgttgccag
     8101 aatccttgtt cattcccgtg ccgaataaat gactgctgta atagcggtgc ttttttcccg
     8161 cctttttcaa cgttcatcct ttccacaccc tttcttccta aaaaaaagag agcgggaaaa
     8221 cgtctaaaac gacaattaac ctgccctctg ttgatactat gacccaaata gtcgcactat
     8281 cattatttgc ggctttttag ctgcgacgtc cgccacggcc accgcgcttt ccttctgtgt
     8341 ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa aaatgaactc atcaatgaat
     8401 cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa agattttttc tgtgctggac
     8461 gatttcggtt gtcacgggga tctttttgtt gatatttttt aggacggctt tcttctccag
     8521 attcagcagg ttgttcctgc gctttccgga tagatagtcc gatttttcca tcatcattta
     8581 ctgaaataac tttaactgtt acttcatctc ctacacttaa aacatcatgg atgtctttta
     8641 catagccatt tgacacttcg ctaatatgaa ctagacccgt ttttccagca cctagatcaa
     8701 taaacgcacc aaaatttgtg attcctgata cttttccttg cagttttgct cctacctcga
     8761 ttgacataaa aaaaatgttc ctcctaatta tttccctttt ttatattcct gcttattttg
     8821 cagttgtaga actagttgat tgatctgttt catttgtcga gctgtctgta tttgattcta
     8881 atataggata aactttttca ccgtcttttg agtaaaagaa tttgcttctg gcaagtttag
     8941 ctacatactc atcatctttc agcaatgaaa catcttggtg cagctgatca acgtctgcgt
     9001 tgacttcttt catttcagta tttgcttcga ctctcaattc gttcaattga tgcatccttt
     9061 gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat gaccaaagca ccaacaaaaa
     9121 ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg ttgttgctga aattcagcat
     9181 actttttctt tgcatattcc gtatctagcg cagcgatttt attgcttttt ttcgtcactt
     9241 ggattcgctc caatcttttt gattgtcttt ttcattatac caatatcgtg aaagcttgtc
     9301 taatctattt ctctagtgtt tctgtgcgat tttcagaaat aatttcgtac attttttgtg
     9361 catcttcttt tttggttgat tcatgtaatt ccgtaatttt cacttccaac gttttgttgc
     9421 caaactggac tttcaaaata tcgcctactt tgacatcact ggaagatttc gccaatttac
     9481 cgttgatttg aattcttcct ttatcagcta cttcttttgc tactgatcgt cttttgatga
     9541 ttcgggaaat ttttaaaaat ttatctaatc gcatatctta ttcctcactt tttaattttt
     9601 ttatttaatc gcaggatttt cttaccaaaa ggcaacatta gccattctcg tactgtaaac
     9661 agacgaagac gaatcactgc ataaatgaac acagaagccc cgatcccaac tcctatcacg
     9721 ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa atactatatt caatacacca
     9781 taatacagca gcagtactac tgtcatacaa agaaggctga acatcaactt ccgtccaaaa
     9841 tgccgttctt tccaaaaagc atttagctct tttgtttcaa ttcgaacaaa ataccaaagc
     9901 gtcacaccta atcctaaaag ggtagacagg cttgcacctg ctgttcctaa taaaccggtc
     9961 agaaaagaag tagtcaatcc ttttaccaat agtccccatc ctgcgccttt taaagaaggg
    10021 cgaaacgagt tcttgctttg agcaatactt tgataagctt ggatgactgc agtgaaagca
    10081 atggaaaaaa caaataatac aagcgctgca tttcccgcat aatctttaaa caacgcataa
    10141 ttgatataag ggagcagcaa ggctaatccc aaagacgcag ctaatgctaa agcggtcgtc
    10201 aatctaagat agattttggc tgtctgtaaa aactgacgat agatccggtt ggtcaaatga
    10261 cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg caatcactaa acctaattgt
    10321 actaaaggct gacctcgatc atagacccct tttgctatct tcgcaccgta ttctgacagt
    10381 ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga tcagctggaa aaagataagc
    10441 aatccactat aaatcgaaac cagtccgcct tctaccagaa aacgccggat caagggcttt
    10501 gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg ctcctccatg aatcttttgt
    10561 tcatagtagt gaaggatccc atatgcgcat aaaccgccaa aaacagctcc actcattgct
    10621 gccgtccctg tttggtacac cgtccatcca agctttctaa aagcaaacgc actacagaca
    10681 atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa cagcagttgg ttccatcaag
    10741 aatcttcctt ggaaattccc tcgataaaaa gatagaccag gcatcagcaa aaaggtaaag
    10801 gaaactactt ggatcagcgg tttcaattgt atgtctccca tcatccaagc aatccagctg
    10861 ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc aaaatactaa gggataaaga
    10921 ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt ctgcaacgta ctttgatatg
    10981 aactgcggaa gaccggataa agctaaagtc attgctatcc cataaattgg ataaacttgc
    11041 tgataaacat aaaaaccttc gtcgccgact aagttttgga ggggaattcg gtaaagggca
    11101 cttaatactt ttgctatgaa agaagcaatc gtcaatacaa atgctccttg catgacgcgc
    11161 cgcatttctt tatgatccaa atcattgctc cttcctacgc tgacagatat ttttgctcac
    11221 gcaacgcttt gacaaacttt tggatttcct gaagccatac tgcttcttcc atttggttgg
    11281 ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc tagactggct tttagttttg
    11341 tcgctgtcag tgcttcgaat aactgttcca cactatagcg ttttgttcca actttactta
    11401 gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc taggagcgct cgatcgccat
    11461 ccattttgat ctgcccaatt gtcaagagat gtgctacttc ttctggatat tctccaaaac
    11521 ggtcgagcag atcatcttct agttcatcta gcatttcttg cgaatcaagt tcacgaattc
    11581 gtttatagat ctcgattttc tgccgttgat ctgccacgta tgtttcaggt agatacgcat
    11641 cgacaccgag gtcgatctca acagtggtct tctccacttg actattcttt ccttgtttac
    11701 gagaaacagc ttcgcttagc atttgagaat acatatcgaa accgactgca tcaataaatc
    11761 catgctgctg agcacctaag agattacctg caccgcgaat ggaaagatcc cgcatcgcaa
    11821 tcttgaatcc agatcccagt tctgtaaaat ctttgattgc ctgaagacgt ttttcactga
    11881 cttcgttaag gatcttctgc tgctcataca taaagtaagc atatgcgaca cggctgcttc
    11941 ttcctacccg ccctcgcaat tggtataacg tggataatcc catataatca gcgttctcaa
    12001 cgaacaacgt atttgcgttc gggatatcta ctcctgtttc aatgatggtt gtagtgacaa
    12061 gaacatcata ttgaccttca ataaattcaa aaagcgtatt ttctaattgc gcctctgtca
    12121 tttgcccatg agcataaccg atccgtgctt ccggaacgag ttcttggatt tcttctactt
    12181 tttgttcgat cgtttctacc cgattatata aatagaatac ttgtccacct cgtcccattt
    12241 ctcgatggat tgcttcgcga atagccccag gatttttttc cataacatac gtttggatcg
    12301 gataacgatt cgcaggcggt gtttcgatta ctgaaagatc ccgcacgcct aacatcgaca
    12361 tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa aacatccact tgtgcacgta
    12421 actgtttcaa tcgttcctta tgttttacac caaaacgttg ttcttcgtca atgatcagta
    12481 gacccaaatc gctaaattca atatcttttg acaaaattcg gtgggttcct acaacaatat
    12541 caacttgacc tgtacgcagt tgttcgatgg tttctttttg ttgctttctt gttctgaaac
    12601 gacttaatag cccgatattt acggggaaac cttcaaatct ttccagcatc gtttcatagt
    12661 gctgctgtgc caagatcgtt gttggaacta aaaaggctac ttgtttgctt tcctttatcg
    12721 ctttaaaggc cgctcgaagc gctacttctg ttttcccata accaacatca cctacgagta
    12781 gtcgatccat tggtttttct ttttccatat cccgtttgat ctccgctgca cttctcaact
    12841 ggtcatcagt ttcagagtag gggaaggcat tttcgaattc tttttggtag gcgtcatcag
    12901 gtccaaaagc atatcctttt tctgactctc ttgcggcata taatttgatt agatcgtcag
    12961 cgatatcctc gatttttgaa gagacttttc gcttggtttt cgtccattca cttccgccta
    13021 gcttattgat gcgaggcgct ttggcttcag aggcgacata tttttggatc agattcagtt
    13081 gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa aatagtcata tagtcttggt
    13141 gaacgccatc tacttctagc gtttccatcc caatgtattt cccgatacca tgattggcat
    13201 ggacaacgta atctcctgct tttaactcat tatagctttt caatcgctct gcgtttgtta
    13261 ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa aatttctttt tctgtgatag
    13321 ctactatttt ttcttgagga agttcaaaac cagcctgcaa agctccttca actaattgta
    13381 cctgtcctct gatcaatgca tttttttctg tttctactac taatatgtct tcatctcgaa
    13441 gcatttgttc tgctttgcgt attctgtcct ttgtcggaat aaagatcaca acagtctgtt
    13501 tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg catttgtccg aagaactgtt
    13561 gcatcgtccg atattgaaaa ttatggattg cttggaaacg aagatttccc atcccttttt
    13621 ggaagagtga gaaaaaggtt gtggtgaact tttccttctg cacgattttt tgtatatctg
    13681 ctgaaaatgt ctgctcagaa aacacccgca attcgctgat tttttgagtc tgccattctg
    13741 ccgcttccct ttcgatttcc cgatttgttt ccatgattcg ctgataatca tcaacgacta
    13801 gtaaactatt tgaagggaaa taatccaaga tcgtcacaga ttcttggtaa agaagatctg
    13861 agtagaattt tgcttcttct gtcgggacac ctgcttgcca gcttgaagtc agctgaccga
    13921 agtaatcttg caaaaactcg cggtctgctt cttctgtggt cgcagcaagc cgtttttcta
    13981 gcattttttg catttgctct attccatgtt ctagatcctc tggtccgtag acttgttcac
    14041 tcgttgggga aacccagatt tcttccgttt tttcgattga gcgttgtgtt tctgcttcaa
    14101 aataccgcat agaatctatc tctacatcaa atagttctac acgaacagga taggttgtcg
    14161 ttaacgggta aatatcgata atgcttcctc gaatactgaa ttctcccggt tttgcgacca
    14221 tctcttctcg tacatagccc atcaaagtca attggcgagg aagattttcc acgtctatct
    14281 catcaccaat atgccaattc aattgcgcct gtagccaagt tttcttattc ggcagtcgtt
    14341 tgtgcaaaga tgcgactggc aacaaataga tacctgcttt tttttcttga agtgcgttaa
    14401 gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa ggccatttca gcagaaagca
    14461 cttcatccac tggaaataaa tggatctgat cttgcggaat cacatgttgc agatcttctg
    14521 ctaactgatt cgcataatac aaatttggca tcagaataat catgttttta tttgttttct
    14581 taaacgctcg agcaaataga agtgttttcg ctgagcccgc taatcctgtg attagttgtc
    14641 taggcatttt ttcttctaaa ttgctgaccc attcttttac ttgcggatct tttccgacta
    14701 attgaataat atccattcct tttcctcctt cctcaattga atcgattcat cgcatccacg
    14761 aacgaatgcc cttctatgag atattcgact gctttaacag attgacacat gctttcttct
    14821 atcaaaggct gattttcttt gctgaaagga ctaagcacat gctggactac tgtttttttc
    14881 ccttctggcc tgccgattcc caccttgatt cgatcaaaga cattcgtatt caaatgggaa
    14941 ataatacttt tgataccgtt atgcccgccg gcacttccct tttgacggag ccggattttt
    15001 cccactgcca gatccaaatc atcgtagatt acgactaatt cctctggata aatcccaaaa
    15061 taagtcatta gtgggccgac tgcacgacca gattcattca tgaatgtttg tggtttgact
    15121 aaaaggatct tttctccatt atgaaaaaat tcggcaactt ctgcttcgaa cggatttttt
    15181 ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga ccataaagcc gatattgtgt
    15241 tttgtatatt ggtatttggt acctgggttt cctaacccga cgatcatttt catttttgtt
    15301 ttccacctaa ttctaaaaag cagcacaaaa ggctggactg ctaattagcg gtccagtcca
    15361 tcgagctttt ttctttttta cacttgtcaa tgcatagtat aacacaaaac aaggcgtttc
    15421 ggctaaaaga gaatcgttaa taaatgataa agaaattaaa aatttcttca aagtttaatg
    15481 aaataattga tatataaaaa tagtgaaata acgcacatgt aagcttttac atataataca
    15541 accttgttat ctgttatatt ttatagccaa atagcgtgac atggggcttg agaaatgtta
    15601 gcataagcat gggaaaaaac aaatcaatgg aaggattgat actaaatgac tgcagctgca
    15661 gaaaaaaaag atcatcaaaa agttattctt gttggagacg gcgccgtagg ttctagctat
    15721 gcctttgctc tagttactca aaatatcgct caagaagtag gtattgtgga tatcaatact
    15781 gctaaaactg aaggagacgc aattgacttg tctcacgctt tggcatttac ttcacctaaa
    15841 aaaatctatt ctgctactta cgcagacgca catgatgctg acttagttgt tattacagct
    15901 ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag taaacaaaaa cctaaaaatc
    15961 aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta acggtatctt tttagttgcc
    16021 gctaacccag tagatatttt gacttactca acttggaaat tctcaggttt ccctaaagaa
    16081 cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt tccgtcaagc acttgcggaa
    16141 ttagttgacg ttgatgcacg taacgtccat gcttacatct taggtgaaca cggagattca
    16201 gaattcccag tttggtcaca tgcaaatgtt gccggcttgc aaatctatga atgggtaaaa
    16261 aacaacccag aaatcgatga agaagctatg gttaacctat tctttggcgt acgtgacgct
    16321 gcttacacaa ttatcgagaa aaaaggcgct actttctatg gtatcgcagt agcattagca
    16381 cgtatcactc gtgccatctt agatgatgaa aatgctgttc ttcctttatc agtattcatg
    16441 aatggcgaat atggattgaa cgacatctac attggtgcac ctgctgttat caaccgtcaa
    16501 ggtatccaaa aagtaatcga aattccttta agtgacagcg agcaagaccg tatggctgct
    16561 tctgctaagc aattaaaaga aattctagat gaagcttttg ctaaactaga cgctgaataa
    16621 tctttgaaca tgacggaaaa catctattcg gtgttttccg tttttttatt ttatcaccct
    16681 tatggtttct aaattttttc ataaagtaga gataaccttc gtcttttcct ctaaattatg
    16741 ctatcatgag accgttccac cctaaacttt tacttaagga gttgtcgata tgacaagatc
    16801 ttcgcatcga aaaaaatcga aacatgttgc tttgctttca gttcttggtg ttctcttagt
    16861 gctgatcagc ttttatacct atcgcagtac atactacaca aagcattttt tgccgaatac
    16921 agaaataaat ggaataaatg tcagcaatct aacagtcgaa aaagcaaatg aaaaattaaa
    16981 agaagcttat tctgataaaa aactggctat taaagaagat ggaaaagtct ggcaggaagt
    17041 accaaaatcc gagctcggct acaaagatga tttcacttcg gagctttctc cgatcctaaa
    17101 tgaacaaaac ggatggactt ggggaatgac ttatgtctca gcggcagaaa aacaagaaat
    17161 agatcctgtc agtcaaaacc accaaaaact agacactacc gttcagacat tgacaactaa
    17221 gctgactgat ttgaacaaag accggacacc tactactgat gcaacgatcg aaaaagcagg
    17281 tgactctttc gttatcaagc ctgaagtcaa tggaaatacg atcgacgtcg atgctgcggt
    17341 caaacaatta aaaagtgcgg taaactctgg taaagataca attgaattga ctgaattcaa
    17401 agaaaaacca aaagtaacat ctgaagacag ctcactgaaa gaacaactcg catccatgaa
    17461 tgctatcgca aatgtaaaag ctacttacag tataaacggt gagactttcc agatcccatc
    17521 aagtgatatt atgagttggc tgacctacaa tgatggaaaa gtcgatttag atacagaaca
    17581 agtacgtcaa tatgtaacag atttaggcac aaagtataac acaagtacga atgacacaaa
    17641 atttaaaagt acaaaaagag gagaagttac ggtcccagtt ggcacttaca gttggacgat
    17701 ccaaacagac agtgagacag aagcattgaa aaaagcgatt ctggcaggcc aagattttac
    17761 tcgttcaccc attgtgcaag gtggcacaac cgctgatcat ccattgatcg aagatacgta
    17821 tatcgaagtt gatctggaga accagcatat gtggtattac aaagacggaa aagtggccct
    17881 tgaaacagat atcgtttccg gaaagccaac tacacctaca cctgctggag tcttctatgt
    17941 ttggaataaa gaagaagatg caactttaaa aggaacaaat gacgatggaa caccttacga
    18001 gagtccggta aactactgga tgccgattga ctggacaggt gttggtatcc acgattcaga
    18061 ctggcaacct gaatacggtg gagacttatg gaaaacccgc ggttcacacg gctgcatcaa
    18121 caccccacca agtgtaatga aggaattatt cgggatggtc gaaaaaggaa cgcctgtatt
    18181 ggtcttctaa caaaaataat atataaaaag aaagcacccg tacgattggt acaggtgctt
    18241 tctttttatt atctaacaat gtgctactta catttcagca gcagtaaaga cttctgaaac
    18301 atcatcatcg tcttctagct tatctactag acgttccaat tgctcttttt gttcctcatt
    18361 taaatcaatc gtcgtttgtg gaatcatcgt caattctgct tgcgccaaag tgaactcttt
    18421 ttccaactca tctcgtacag cagcaaaatc ttctggtgca gtataaatct cgaatacttc
    18481 aggagaagtt tgcagatctt ctgcccccgc ctctaataca tcctcaaaca tcgtctcttc
    18541 atcaacagtc aacccatcgc gttcaatagc gatatatcct ttgcggtcaa acaagtaact
    18601 gactgaaccc gtttctccca gtgatccacc gtttcgagta aaagctactc ggacatttgt
    18661 cgctgtccga ttacggttat ctgtcaatgc atggactaag attcctactc cacccggacc
    18721 atatccttca tacgtgattt catcgtaatt cgtttcatct acggcactcg tagccttttt
    18781 aatcgcccgt tccacattgt cgttaggcat atttgcagct tttgctttgt ccacaacaag
    18841 ccgcaaagct ggattcatag atggatcagg accgcctgct ttagctgcca tataaatttc
    18901 acgagaaagt ttctgaaaga ctttccctcg ttttgcatct tgggcatttt ttcttccttg
    18961 gatattatgc catttactat gtcctgacat gatttttcct cccttgttct tttgagaata
    19021 cacttctatt ctagtactat ttcacaaaaa aacaaagcca cagccaatct ataaacgctt
    19081 cttgaatgcc gcaaaaagca cacataatat cacagcagtc agagcaccga tcgaatccaa
    19141 catgacatct tggaacatag gtgttcgtcc accggtcatc atctgatgga attcgtccaa
    19201 acctgcgtac cctgttgctg aaagccaagc aaggatcgct gtcagccacc aaatttttag
    19261 cttggggaaa acacctaaaa acaagctgcc tcccaaaata aaataggtac cgaaatgtgc
    19321 gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc agatggttga tactcaccat
    19381 acttccacca taattaaaac gtatacccgc taatgtgtct ttaaatggct gattaggcag
    19441 ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa gtttgagaag aactgtaaaa
    19501 taagattata acgactatca gtgcgattac taaataaata tttccgtttt tcatttgttt
    19561 ttttgaagaa ttca
//
LOCUS       DAFLWZ010000051        19458 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000051 DAFLWZ010000000
VERSION     DAFLWZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.051"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            134..3661
                     /locus_tag="L1V38_001910"
     CDS             134..3661
                     /locus_tag="L1V38_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBN1316459.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="L1V38_001911"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="L1V38_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBN1316460.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="L1V38_001912"
     CDS             7449..7790
                     /locus_tag="L1V38_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316461.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="L1V38_001913"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="L1V38_001913"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBN1316462.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /locus_tag="L1V38_001914"
     CDS             9147..11567
                     /locus_tag="L1V38_001914"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBN1316463.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="L1V38_001915"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="L1V38_001915"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBN1316464.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13001..13738
                     /locus_tag="L1V38_001916"
     CDS             13001..13738
                     /locus_tag="L1V38_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1316465.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13752..14567
                     /locus_tag="L1V38_001917"
     CDS             13752..14567
                     /locus_tag="L1V38_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1316466.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14580..15227
                     /locus_tag="L1V38_001918"
     CDS             14580..15227
                     /locus_tag="L1V38_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1316467.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15243..15899
                     /locus_tag="L1V38_001919"
     CDS             15243..15899
                     /locus_tag="L1V38_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1316468.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16061..16882
                     /gene="racE"
                     /locus_tag="L1V38_001920"
     CDS             16061..16882
                     /gene="racE"
                     /locus_tag="L1V38_001920"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBN1316469.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16885..18240
                     /gene="rph"
                     /locus_tag="L1V38_001921"
     CDS             16885..18240
                     /gene="rph"
                     /locus_tag="L1V38_001921"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBN1316470.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18241..18759
                     /locus_tag="L1V38_001922"
     CDS             18241..18759
                     /locus_tag="L1V38_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1316471.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18866..19366
                     /locus_tag="L1V38_001923"
     CDS             18866..19366
                     /locus_tag="L1V38_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1316472.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6541 a         3340 c         4178 g         5399 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcactgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaataa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa ccgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataactaa tagattagaa atggaagaaa tatttatggg agaataaacg
    12901 ttctaagaaa ctttacaaat tactaaacta tcagatataa tgtattttat tatacatctt
    12961 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
    13021 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
    13081 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
    13141 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
    13201 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
    13261 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
    13321 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
    13381 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
    13441 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
    13501 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
    13561 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
    13621 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
    13681 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
    13741 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
    13801 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
    13861 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
    13921 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
    13981 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
    14041 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
    14101 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
    14161 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
    14221 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
    14281 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
    14341 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
    14401 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
    14461 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
    14521 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
    14581 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
    14641 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
    14701 aattatcaaa gaataaagta gtgagcgcct tagcaaaggc atatgtagaa ttttttagaa
    14761 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
    14821 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
    14881 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
    14941 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
    15001 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
    15061 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
    15121 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
    15181 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
    15241 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
    15301 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
    15361 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
    15421 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
    15481 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
    15541 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
    15601 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
    15661 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
    15721 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
    15781 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
    15841 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
    15901 agatgattct tttagcggtt gtggcaaact aaagtcacaa ccgcttttcc tctttccatt
    15961 cgaaaaaaag agatttcgat tgttttaagc aagtaagagc acttgaaaat tcacgctaaa
    16021 aagtacacaa tagggaggat agaatttatt gaaaaaaagg atgatacgat tgacagataa
    16081 tcgccctatc ggatttattg attcaggtgt cggcggcttg actgtagtaa aagaagccct
    16141 gaaacaatta ccgaatgaaa atattttatt tgtaggagac acagcacgct gcccatatgg
    16201 ccctagaccc gcggaacagg taatccagta tacttgggaa atgacggatt atctggtgga
    16261 gcaaggaatc aagatgctgg tgatcgcctg caataccgca actgcggtgg ctttagaaga
    16321 aatcaaagct gctctttcta ttccagtcat cggtgtgatc cttcccggta ctagagcggc
    16381 agtaaaaaaa acacaaaata aacaagttgg cattatcggt acgattggta cggtaaaaag
    16441 tcaagcttat gaaaaagcac tgaaagagaa agtaccagaa ttgactgtga caagtcttgc
    16501 ttgtcccaaa tttgtttcag ttgtcgaaag taatgaatac cattcatcgg tggcgaaaaa
    16561 aattgtggca gaaacattag ctcctttaac cactaaaaaa atcgatacat tgattttggg
    16621 atgcacccat tatccattat tacgccccat cattcaaaat gtaatgggag aaaatgttca
    16681 actgatcgat tctggagcag aaacagtagg tgaagtatct atgctgttag attatttcaa
    16741 tttgagcaat tcaccgcaaa atggtcggac attatgccag ttttatacaa ctggctctgc
    16801 caaacttttc gaggaaatag ctgaagactg gcttggaatc ggacacttaa atgtagaaca
    16861 tatcgaattg ggaggaaaat aaggatgcgt catgacggga gaaaagccca agagcttcgc
    16921 aaactggagc ttcaaacaaa tgttttcaaa tatccagaag gatcggtagt gatccgtttt
    16981 ggtgatacaa cagttatttg ttctgcaaca atagaaaatt ctgttccccc ttttttgaga
    17041 gaaacaggaa caggatgggt gacagcagaa tatagtatgc tgcctcgagc aacgagtacg
    17101 agaaatcgta gagaaagcag caaagggaaa ctttctggta gaacaatgga aatccagcgt
    17161 cttattggtc gttccttgcg tgcagtagta gacttggaaa aattaggaga acgtagtatc
    17221 atcgtagact gcgatgtgat ccaagcggat ggcggtacta gaacagcaag tatcactggg
    17281 gcatttgtgg cattgaaatt agccattgaa aaacttttaa gagaaaaaga attgtcagaa
    17341 gatccaataa aagaacatct tgctgcagtt agcgtaggaa tcttaccaga tgggacttgc
    17401 gtcacagatt tggattacca agaagattcc gcagcacttg tagacatgaa tcttgtaatg
    17461 acagaatctg gaaaattcgt ggagattcaa ggaactggag aagaagcaac gtttgatggt
    17521 gaacagttga atgaaatgct cttttttgga aaaaacgcga ttgaagattt gatcaaagag
    17581 caaaaacatg ctttgctaac agagtttgct caaaatgatg agcggataga agaaacaaaa
    17641 acaatcatca ttgcgacaag aaatccagga aaagcagaag agtttcgaaa tatgttcaaa
    17701 gaagcgggat atcatgtaaa aacattactt gactatcctg aattgccaga tgtggaagaa
    17761 actggcagca catttgaaga aaatgcccga ttaaaagcag aaacgattgc acaattgctt
    17821 gatcagccag tcttagcaga tgattcaggt ttgaaagtgg atgctttagg cggtatgcca
    17881 ggaatctatt ctgcacgttt tgcaggggaa caaaaaagtg atgcggggaa taacgccaaa
    17941 ttattatatg aattgacaga tgtgccggat gaaaaaagaa cagcacaatt ccattgtacg
    18001 ttagtattcg cggcacccaa aaaagacagc cttgtagtag aagcggaatg gcccggtcga
    18061 gtagcccgta taccatctgg cgaaaatggc tttgggtatg atcctttatt tatcccagaa
    18121 ggtaagaaac aaacagcagc agaattatcg agcgaagaaa aaaacaagat cagtcatcgg
    18181 gctcaagcaa tgaaaaaatt gagtgccgag tggaaacaat ggctggaagg agagagatag
    18241 atgcggtatt tagtagtaag tgataatcat ggagacagag atatcctcgt tgacttagta
    18301 gatcgttatc gttctgaagt ggatatcttt ttccattgtg gtgattcgga attagaagct
    18361 tctgacccat tatgggatac attccaagtg gttcaaggta attgtgatta tggaccagga
    18421 ttcgaacaga aaaaagtgat ccaaactggt caggatacag tattcatgac tcacggtcat
    18481 ttatcgaatg tccgatttgg tttgacacag ttagcaatcg aagctcgagc tgcaactgcc
    18541 gatatggtgt tttttggtca tacccatcaa ataggctgtg agatggatca gaaaatcctg
    18601 tttttgaatc ctggtagcat ttctcagcct agaggcccga tccaaatccc atcatatgct
    18661 cttatcgaaa gtttagatga ccaaatttct gttcaatact ataaccgtgc ccatcaggca
    18721 gttgaagagt tggccttttc tttttcgaga gagcgctgaa taaaaaaact ctaattttta
    18781 ataaaaataa gctttatttt atgaattttg catccggttt cggtaaaata gtagtgttga
    18841 atgaaataga aatggaggcc atcagatgat tggacctata gtaagagaaa tgctgctgga
    18901 aaatcaggaa acgtttttga ttcctgcaga aaatgtggca aatgttatgt atcatcatcc
    18961 attgtcccat ggtttacttg tgttatcgaa ggtcggttat tccaaaattc ctgtattagg
    19021 aaaagatgat cactttgtag gactagtaag tttatcagat gtggtcaata aaatgattga
    19081 cttgcaaaca atcagcatgg acccgttaga aggactaacg gttgctgatg tgacagaaac
    19141 agatgttccg acaattgatg aaaattggga actagaagaa gtactccatt tgttagtcga
    19201 ttcgcctttt ttaccggttg tcacagaaga tcggattttc aaaggaatca ttacaagaaa
    19261 agagctgctt aaagccgtaa acttcatggt gcatgaatta gaacgtcgta atatattgtc
    19321 tccgaaaatc gaagaattaa aagaacaaat cgatatcgtg agctaaagaa cgagaaacta
    19381 aaagataatc aaaaaataag tagaaaaaac agcgtaccag ttttgacttt atcttgaaaa
    19441 agaggctggg acaaaagc
//
LOCUS       DAFLWZ010000052        18686 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000052 DAFLWZ010000000
VERSION     DAFLWZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.052"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            129..776
                     /locus_tag="L1V38_001924"
     CDS             129..776
                     /locus_tag="L1V38_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1316473.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    905..1121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1169..3814
                     /locus_tag="L1V38_001925"
     CDS             1169..3814
                     /locus_tag="L1V38_001925"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBN1316474.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4124..5437
                     /locus_tag="L1V38_001926"
     CDS             4124..5437
                     /locus_tag="L1V38_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBN1316475.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5427..6080
                     /locus_tag="L1V38_001927"
     CDS             5427..6080
                     /locus_tag="L1V38_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1316476.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6135..6827
                     /gene="radC"
                     /locus_tag="L1V38_001928"
     CDS             6135..6827
                     /gene="radC"
                     /locus_tag="L1V38_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBN1316477.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6977..7177
                     /locus_tag="L1V38_001929"
     CDS             6977..7177
                     /locus_tag="L1V38_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1316478.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7431..9110)
                     /locus_tag="L1V38_001930"
     CDS             complement(7431..9110)
                     /locus_tag="L1V38_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1316479.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9112..9324)
                     /locus_tag="L1V38_001931"
     CDS             complement(9112..9324)
                     /locus_tag="L1V38_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBN1316480.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9717..11447
                     /gene="efrA"
                     /locus_tag="L1V38_001932"
     CDS             9717..11447
                     /gene="efrA"
                     /locus_tag="L1V38_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBN1316481.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11444..13204
                     /gene="efrB"
                     /locus_tag="L1V38_001933"
     CDS             11444..13204
                     /gene="efrB"
                     /locus_tag="L1V38_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBN1316482.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13299..13496
                     /locus_tag="L1V38_001934"
     CDS             13299..13496
                     /locus_tag="L1V38_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316483.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13649..14134
                     /locus_tag="L1V38_001935"
     CDS             13649..14134
                     /locus_tag="L1V38_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBN1316484.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14238..14831)
                     /gene="clpP"
                     /locus_tag="L1V38_001936"
     CDS             complement(14238..14831)
                     /gene="clpP"
                     /locus_tag="L1V38_001936"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBN1316485.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15011..15538
                     /locus_tag="L1V38_001937"
     CDS             15011..15538
                     /locus_tag="L1V38_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316486.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15629..16366
                     /locus_tag="L1V38_001938"
     CDS             15629..16366
                     /locus_tag="L1V38_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1316487.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16370..17287
                     /gene="miaA"
                     /locus_tag="L1V38_001939"
     CDS             16370..17287
                     /gene="miaA"
                     /locus_tag="L1V38_001939"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBN1316488.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17289..18518
                     /gene="hflX"
                     /locus_tag="L1V38_001940"
     CDS             17289..18518
                     /gene="hflX"
                     /locus_tag="L1V38_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBN1316489.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(18552..>18686)
                     /locus_tag="L1V38_001941"
     CDS             complement(18552..>18686)
                     /locus_tag="L1V38_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1316490.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT         6037 a         3228 c         4058 g         5363 t
ORIGIN      
        1 ccgcagatgc aagcttttga acaccgtttt atttgtctca cacccttttc cttcctactt
       61 gtaaccttgc tcccgtgtta gaaacatgtt acactaaata tgtgaaatta ttaacaagga
      121 gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc aactgcgaaa agattacctt
      181 tatatttacg ctacttgaag ttgctggatg actcaggtat aagtagaatc aaatcaaatg
      241 agttcagcga aatcacccaa attccttctg caacgatccg cagagacttc tcgcaattag
      301 gcgagctagg cagaagcgga tatggctatg atgtcccttt tcttatcgat gtattcaata
      361 atatccttaa tactaaagaa gaaaaacgaa tcgcattagt aggatatgga aatcttggca
      421 aagcattgaa acacaacaat tttagaagaa atgaaaatct aaatatcgtg tgcgtctttg
      481 ataatgatcc agcactgatc aatcgagtaa ttgatggaga aatgatctat ccgattgatc
      541 gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc aatctctacg gtaccaagta
      601 aatattcaca atctgctatt gatgaaattg tcaaaggaaa tgtaaccgct atacttaatt
      661 ttgcgcctga cagagtaact gtcccagctt atgtcaatgt tcaatacatt gatttgacaa
      721 ccgagttgca gacgcttatt tactttgatg agaattactc agaagttttt tcttaggaaa
      781 atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa ttctttcaaa aattttttag
      841 tactaaatga agtggttttt tcacgaccac ttgttgacta aaaaaaaaaa ccattgtaga
      901 atgaagcata acgctgaaca agaggagtaa ctggcacatt cattcttaga gagagaacta
      961 tctgctgaaa ggttctcaat gacaaccagt gaaggtagct tgggagtttc tgtcttgaat
     1021 ggagtagaga tagacgagtc gtgatcgtta actcacttga gaggcaataa tgattgatta
     1081 ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga atacgaaagt attttaggac
     1141 gttttttagt ttaaaggagg aaaacagcat gacggaagaa aataacctat caacaaaata
     1201 taatccgcaa gaagttgaag ctggacgtta tcagcattgg ttagaacaag atttgtttaa
     1261 accgagcgga gataaaaaag caaaacctta ttcaatcgta atcccgcccc caaatgttac
     1321 tggaaaactt catttagggc atgcttggga tacgaccttg caagatatgc tgattcgtca
     1381 aaagagaatg caaggatatg atactttatg gctgcctggt atggaccatg caggaatcgc
     1441 gacacaagca aaagtagaag cgaagcttag agagcaaggg atttctcgtt atgatctagg
     1501 tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa gagtatgcga gccacatccg
     1561 cgaacagtgg gctaaaatgg gcttatcttt agattacagt agggaacgtt ttacattaga
     1621 tgatggatta tctgaagcag tacgtaaagt ttttgttacc ttatacgaaa aaggtttgat
     1681 ttatcgtggt gaatatatca tcaactggga tcctcaagca cgaacagctc tatctgatat
     1741 cgaagttatt cataaagata tcgaaggcgc cttttatcat atgagctatg aactagcaga
     1801 tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa acgatgttgg gagatacggc
     1861 gattgctgtt catccagaag acgagcgtta tcaagcgctc atcggcaaaa aagtgattct
     1921 acctttagtc aataaacaaa tcccaatcat tgcagatgaa tatgtagata tggaattcgg
     1981 gacaggtgta gtaaaaatca ctccagcaca tgatccaaac gactttgagg taggtaatcg
     2041 tcatgatctt ccacgcgtaa atgttatgga tgatgatggt acgatgaatg aactagcagg
     2101 aaaatatgct ggaatggaac gttttgctgc tcgtaaagca atcgtgcaag atctgaaaga
     2161 aatcggtcga ttgattaaaa tcgatacgat gatccacagt gtgggtcatt ccgagcggac
     2221 aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt gtaaaaatgg cgccgttagc
     2281 gaaaaaagcc attgataacc aagaaacaga tcaagcagtg gaattcttcc ctccaagatt
     2341 caatcaaacg tttttacgtt ggatggaaaa tgtccatgat tgggtaatct cacgacaatt
     2401 atggtgggga catcaaattc ctgcatggta tcacaaagaa acaggtgaaa tgtatgtagg
     2461 gatggaagca ccagcggata gtgaaaactg ggtacaagat cctgatgttt tagacacttg
     2521 gtttagttca gctttgtggc ctttctcaac aatgggctgg ccagatacgg aaagcgaaga
     2581 ttataagcga tacttcccta ctagcacttt agtaaccggt tatgacatca ttttcttctg
     2641 ggtaagcaga atgattttcc aaagcttgga atttactggc gaacgtccat ttgagaatgt
     2701 cttgattcat ggattgattc gtgacgaaca agggcggaag atgagtaaat cattaggtaa
     2761 tggaatcgat ccgatggaag taatcgaaaa gtatggagca gatgctctcc gctggttctt
     2821 atcgaatggt tctgcaccag gacaagatgt ccgcttcagc tatgaaaaaa tggatgcttc
     2881 ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc gttatcatga atatcgaagg
     2941 aatgaccgta gaagagatcg atttatctgg agaaaaatca gtggctgacc ggtggatcct
     3001 tactcgtttg aatgaaacga tcgaacgagt aactgagcta tttgatcgtt ttgaatttgg
     3061 tgaagcaggt cgacaactgt ataactttat ctgggatgat ttttgtgact ggtacatcga
     3121 aatgagtaaa gaagtacttt atggagatga tgctgtttca aaacaaacca cccgtagcat
     3181 cttagtccat acacttgatc agatcctacg tttattgcat ccaatcatgc cattcgttac
     3241 agaagaaata tgggaacata ttcctcatca gggaaattct ctagtagtgg cagaatatcc
     3301 tgttgtacgt ccagagtttg atgatgaaac agcttctaaa gggatggaag tattgaaaga
     3361 attgattcga gccgttcgaa atattcgttc agaagtgaat acaccattgt ctaaaccaat
     3421 tacgttgcta attaaaacaa acgatgctaa aatcgatcaa tttttagttg aaaatacaag
     3481 ctatatcgaa cgcttctgta atcccgaaga gttgacgata tcaagtgaga tcactgcgcc
     3541 agatctagcg atgtcagctg ttctgacagg tgcagaaatc ttcttgccgt tagcaggatt
     3601 gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa ctggaaaagt ggacaagcga
     3661 agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt gtttctaacg cgccggaaga
     3721 agtagtagag gcagagcgtg caaaagaaaa agattattta gagaagcaaa cggctgtcaa
     3781 agaacgaatc gaaagtttgc gtactattca ataagaatag aaaaagagag tgtgaaatca
     3841 gctagctatt actaaaagct agctgattga acatcgttac aggaaagagt ttgagcctca
     3901 ctcttagctt cgattcataa ggagatgtga cataaatttt gtcgcatctc ttttttagtc
     3961 tactcttatt atgtaggaga aggagggagg tggatcatgt atcaagagtc aataaagtag
     4021 ttgataaaat cgttcctctc tctgtttctt ttctctttgt catactttta tttttcttat
     4081 gtgttctatt tgttataata aaagagaaat gggggaattg ttgatgacga ttgaagaagc
     4141 aatagaatgg atccatagtc gattaccatt tggttcacgt cctggccttg accgagtcga
     4201 agctttatta gaagtggtag ggcatccaga gagaaaagta aaaacgatcc atatcgctgg
     4261 aacaaacgga aaaggttcta ctgtagctta tttgagaagc ctattagaag aggctgggct
     4321 gacagtaggt acatttactt caccttatat cgaaacgttc aatgaacgga tcgcaatcaa
     4381 tggcaaaagc attccagaca atgatttgat ccagcttgta aaaaaatatc agccactgat
     4441 caaacaactt gatcaatttg aagcagtagc tggtattact gaattcgaga cattaacagc
     4501 aatggcattt gattattttt tgatgaagaa agtggacgta gcgattatcg aagttggctt
     4561 aggcggctta ttggattcta ccaatgtagc tgtaccaatg ctgacgggaa taacaacgat
     4621 tggacttgat cataccgaaa tacttggaga tacaattgaa gaaatcgctg cacaaaaagc
     4681 tggaatcatc aaacaaggcg ttccagtagt aacaggaaat attgccccag aagcttttac
     4741 tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt tatgtatacg gggaaaatta
     4801 taaaataaac tatctgcatc ctgatgagat gtggggagaa gtatttgaat tttttaatga
     4861 aataggaaag atccctcaat taaccactcc gcttttaggg caacatcaag ctgaaaatgc
     4921 aggagtagcc atcgaattgt attttgttta ctgtcaattg gaaaagctgc ctttccgaga
     4981 aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca ggaagaatgg agcgtttgag
     5041 taacgagcca ttagttgttt tagatggtgc ccataatacg catgcaatga accggcttgt
     5101 tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac attttgtttt ccgccttacg
     5161 aactaaaaat gttagagaaa tgctagaacg attgcagcaa gtaccaaatg tccatattta
     5221 tttgacgacc tttgaacatc caaaagccat cgaattaagt gaagtatcag atttagcaag
     5281 tgagagagta tcaatcgttt cattgtggca attcggatta gcagatatat tggaaaagat
     5341 gacaaatgaa gacgtattag ttgtgaccgg ttcactttat ttcatttcag aagttcgcca
     5401 tttattaata caattaggag gagatcatga agtataatgc agtgattttt gacatggatg
     5461 gtttgctgtt cgacacagag ttagtgtatt acgaagccac acaagtagta gcagacaaga
     5521 tgggttttcc ttatgataaa gacctgtatt taaaattctt aggtgtttca gatgaagaag
     5581 tatgggcgaa ttatcatatg attttctcgg aatttggcaa aacaagtgta caaagattca
     5641 tagatgattc ataccaggaa acgcttgaac gtttttcgca aggagcggta caaatgaagc
     5701 ccggtgtgtt ggaactcctc tcttttttag aagaacatca gattcccaaa gttgtcgctt
     5761 ccagtaacca acgagcagtc attgaacttt tattgaagaa gaacaatctg tttgaacgat
     5821 ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa accagaccca gaaattttct
     5881 tgttagctaa tcagaagcta ggtacagcga agaaagaaac attgatttta gaagattcac
     5941 aaaatggtat tttagcagct tctgcggctg agatcccggt agtcatggta ccagatctgc
     6001 ttccaccatc ccaagaattg atcaaaaaaa cagctggggt tgtttcttct ttacatgaaa
     6061 tccctgcatt gttaaaataa aaatccatct cttttcgtat cttattttag ataagataga
     6121 aaggagatgt ttttttggga aaacgattga tcaaagaagt acctactagc tctttaccaa
     6181 gggaacgtat ggaaatttat ggcgcggaag ctttatcgga tcaggagctt ttggcaatct
     6241 tactgcgtac cggtcaacac ccttatagtg tgatgtcgat tgctggaaat ctgttaaaaa
     6301 cgtttggagg actggcctct ttacgacagg ctactttgca tgagttagaa gagattcgag
     6361 ggataggacg cgtgaaagca atcgaaatca aagccttgat cgaattaggt cgacgaattc
     6421 agacggatca tgaaagagcg gctccaccgg ttcgtaccag ctacgaattg gcccagcaat
     6481 tgattctgga aatgaaagat cacaaacaag aacatttggt ttgtatttat ttggacacga
     6541 agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc gctgaatcag tcagtcgctc
     6601 atcctagaga aattttccat tatgctgtac gttattgtgc agcaaggatc gttttagcgc
     6661 ataatcatcc ttctggtaat gttattccat cgcagcagga tatgaatttt accaaaagga
     6721 tacaaaagtg tggagaaatg atggggatca ctgtactgga ccacttgatc atcggacgca
     6781 aacgatattt tagtttgaga gaagaaggaa tgatggaaga gaagtaagtt gctttcttgc
     6841 aaaaaaaatg aagcaagtgt acaattatat tgtaattttg tttgggaata gaagttgaaa
     6901 catctgttgc acctctatcg tacacgagca atgttacaat ttaaattagt gcttttggca
     6961 cgaggaggat attattatgg aaaacggaac agtaaaatgg ttcaacgctg aaaaaggatt
     7021 tggatttatc tcacgtgaag atggaagcga cgtattcgtt cacttctcag ctatccaagg
     7081 tgacggattc aaaacattag aagaaggtca agcagtgact ttcgacgttg aagaatcaga
     7141 ccgcggccca caagctgcaa acgttgtaaa agcttaattt tatctgtaaa tcaaattgat
     7201 ggtagacatc aatttttacg agagaacaaa gcgagtaaca aaaatacctg ccacaagaga
     7261 caatttctct tgtggcaggt atttttttgt atgaaaaagt aaataaattt aagaggctat
     7321 gaaagagcca ccttgtatca aggaataaga acaaacaaaa atggcttctc atgtttttca
     7381 tttgttttct cttatattca ggacaaggtg ctgatttcat aacctcttat ttattcttca
     7441 tctggtgtca ttaccattgg caaaatcatt ggatgtcttt ctgtacgttc gaataagaaa
     7501 ggctgaagcg cgccagtcat cgcttctttc aatttatatt ctgaacagtc aggtccattc
     7561 aaacattctc ttaaagcgtg gaataagatt cgctgagctt cattgatcat ttctcctgat
     7621 tctcgcatgt agacaaatcc acgagagaga atatctggac cagccaagat ttcttttttc
     7681 ttgatatcca ctgtcgcgac agctaataca agaccttctt ctgaaagcag gtgacggtca
     7741 cgtaaaacga cattaccaat atcaccgatc ccgctaccat cgatatacac atctccagcc
     7801 acaaaatgcc cagcaggacg cgcagaatcg ctagttaacg ctaaaacatc gccattttcc
     7861 atgatgaagc agttttctgc aggaacacct acatcttgtg ctagagaagc atgtactttc
     7921 aacatgcgga attctccgtg gacaggaata aaatattttg gcttcatcaa acgaagcatt
     7981 aatttttgtt cttcttgtcc accgtgaccg gaagtatgga tgttattgat ttttccgtga
     8041 atcacttctg caccagcttc agacagcaaa ttgatcaaat gattgacact tgttgtatta
     8101 ccaggaatag gtgaacttga aaagatcact gtatcgtctg gctggatttg gatttgacgg
     8161 tgagtaccat tcgcgatgcg gctcaacgcg gccatcgctt ctccttgaga acctgtacat
     8221 aggatcatcg tttcattggc aggcaagcga ttgatttcgt gtgcatctac aaatgtgccg
     8281 tctggaactt tgatatatcc taaacgttga ccgttgacga tggcattttc catgcttcgt
     8341 ccgaaaacag cgattttacg accagttgcc acagcggcat ctgctgcttg ctgcaaacgg
     8401 aagatgttag aagcaaagct ggcaaaaatg atacgtcctt cgatttttga aaagatcttc
     8461 aaaatagaat gcccaatcgt tttttctgat ttagtaaatg ttggaatctc agcatttgta
     8521 ctatcagata aaaggcacaa gactccttct tccccgatac gagccatttt atgcaagttt
     8581 gctggttcgc caacaggagt gaaatcgaat ttgaagtctc cagtcgctac gatatttcca
     8641 gaaggtgttt tcaccacgat ccctaatgca tctgggatac tatgggtcgt tctgaaaaag
     8701 ctgacagaag tctttctaaa acggatgatc gtatcttcat tgatctcatg gagctctgca
     8761 tctcgaagca agccatgctc atctaatttg tttgtgatca acgctaatgc gagaggacca
     8821 gcatagatag gaatatttgc ttgtttcagc aagtagggta ttccgccgat gtggtcttcg
     8881 tgcccgtgag taatcaccaa ggcttttact ttgtgtaagt tttgtatgat gtagctgtag
     8941 tcgggaatga catagtcaat tccaagtaaa tcgtcttccg ggaatttgat cccggcatca
     9001 atcaaaatga tttcatcttg gaattgtacc ccatacgtat ttttcccgat ttcacctaat
     9061 ccaccaatag caaagacgcc tgtctcgtta tttttgatgg aaagtttcat attaaaactc
     9121 cactaatgag aaatcagcat tttctttttc gtactctaga tgacttcctt ctagaagttg
     9181 aacgaattca atattgtatg gggtattttc ttccacacgt tggcgagcgt ctacatcgct
     9241 ttttgcctca atgtaaagag attttgtttc ttcccgttta gggttgcgta cttttgtttc
     9301 ttgataataa actttataga tcattgtttt gtctccttta tctgcgtaaa gcagtgattt
     9361 agctagttga tttttttaga caacacaaaa cgaggggaca agccacctgg tttttcatat
     9421 gctttgacta gaatactgga ttcgagtcaa agagacaagc ctcgtttttg cttatctgtt
     9481 cggatatttt ttcaaccgta ccttctgtat aaaaaatata caacaattaa ttgttattct
     9541 agcataaaac agcaaataag tatagaaatc aactagattg aaagaaaaaa tcaatgttta
     9601 tcatcccgct ataatcataa tgactttttt atgagagaag tgttctatta ataggctcgt
     9661 tgtgctatca tttttagtaa tgaaaatgta acaaaagatt aaaaggagat gagaaagtga
     9721 aactaatgtg gcattatacc atgcgttata agaaattctt gtttttcaat ttcatatgcg
     9781 tatttggttt tattttgatt gaattaggac ttcctacgat tttagcacgt atgatcgatg
     9841 taggaatccg caatgatgat tttgattatg tgaagcaaca agggatattt atgatcgtta
     9901 ttactgtaat cggtattatt ttgaatatct tgttaggtta ttttggttcg aggattacga
     9961 ctaatatcgt agcagatatt cgagatgatt tgttcgaaaa gatccaaagt tattcgcatc
    10021 aggaatacga aaatctaggc gtatcttcat tgatcactcg tacaacaaac gatgcttatc
    10081 agatcatgtt gttcctgcaa aatattttac gtatcggttt tatggcacca atgatgttca
    10141 ttgtcagttt gtacatggtc atgcgtacaa gtgtgacact cagtttgtat gtagtaggtg
    10201 cattaccttt actattattg gcagtcgtag cgattgctaa ggtgtctgaa ccgttatcta
    10261 aaaagcaaca aaaaaactta gataaaatca acagtatctt gcgggaaaat ctttcaggat
    10321 tgcgtgtgat tcgtgcattc gtcaatgaaa agtttgaaga aaaacgtttt gctgtagtca
    10381 atgagaatta tgcttctagt tcaaaaagct tattccgttt gatggctgtt gcacaaccgg
    10441 gtttttattt cttatttaat atcgtaatgg tattgatcat ctggagcggg gcagtgcaaa
    10501 tcgatgcagg cgagcttcgt gtaggagatt tgattgcgtt tatcgagtat atattccatg
    10561 ccttgttctc attcatgtta tttgctagtg tgttcatgat gtatccaaga gcagctgttt
    10621 cagctggacg tatccaagaa gccctagatg ccaaaccttc gattgtagaa gatccaaatg
    10681 gtatatctga tacaaaaact aaagggtata tcgaatttca aaatgtaaca tttgcttatc
    10741 caggccattc gcaagagcca gtgatacgaa atgtcagttt tacagcctct ccaggagaga
    10801 ccgttgcttt tattggaagt accggtagcg gaaaatctac gttgatccaa ttgatccctc
    10861 gcttttatga tgtgagtgaa ggaaagatct tgatcgatgg agtagacgtg agagattatc
    10921 ggctaagcaa gttgcgagat aagattgggt ttattccgca aaaagcgctg ctatttactg
    10981 gaacgattgc agataatttg cgatacggga aagaagatgc tacgcaagaa gaaatggaac
    11041 gtgcagctga gattgctcaa gcttcagaat tcatttctcg aaaaccagat ggatttaatg
    11101 aacatttatc agaaggtggt tccaattttt caggtggaca aaaacaacga ttggcaatag
    11161 ccagagccat catacgccgt ccggaaatct atatttttga tgacagcttt tctgcattag
    11221 attatcaaac ggatgcgaag ttacgtgctc gtctgaaaaa agaaacgaca gaatctactg
    11281 tattgatcgt agcacaacgt gtgggaacga tcatgcatgc agataagatc atcgtattaa
    11341 atgaaggaga agtcgtcggt atggggacgc atcgggagtt gttggaaaaa tgcccgattt
    11401 attatgatat tgccgcttct caattatcaa aggaggaatt agcatgaaaa aaaccttttc
    11461 ttccttaaaa cgtttagctc gatatatcag accgtatcgt gagacttttc ttttagtgat
    11521 cctatttaca gttctgacag tggctttcaa cgtggctttg ccatatgtta caggacttcc
    11581 tactacagaa atcagccgta atattgccaa tggcgaatca atcaattttt cttatatatt
    11641 caaatgtctc atttggatca cagttgttgg aatagggtat tgtatttcgc aattactttc
    11701 tggtgttttg atgacaaatg tcgttcaaag tgccatgcat gatttgagaa gagacataga
    11761 agaaaaaatc aatcgtcttc cggtttcata tttcgataaa aaccagcaag gaaatatttt
    11821 gtctcgtgtg acgaatgatg tagatgcagt cagcggtgct ttacaacaag cttttattgg
    11881 tatcgtaaat gcgatattgg gaattacgtt ggctgcagca atgatgtttt atatccagcc
    11941 gatgatggcg ctgatctcta tgatcatgat tccaacatcg atctggatct caaaacgagt
    12001 gatcaatgct tcgcagaaat attttcaaag catgcagaat tctcttggtg agctaaacgg
    12061 ctacgtccaa gaaaatatga caggttttag tgtattgaaa gtatatggac gcgaaaaaga
    12121 aacattggaa ggattcaaaa aagttaatca cagcttgaaa tactttgggt ttcgtgcagc
    12181 attcatttct ggcttgatga tgcctctagt tcaattaact gcctatgcta cttatattgg
    12241 tatggctgtt ctaggaagct tttatgttat tactggggcg atcgttgtcg gtcaactaca
    12301 agcattcatc caatatattt ggcaaatcag tcagccaatg gggaacgtga cacaattgtc
    12361 ttcagttttg caaagtgcat cagcggcaac gaaacgtgta ttcgagattt tagatgagcc
    12421 agaagaaaaa gaaaacaaag tagatgcttc actgccagaa acgattttag gagatgtgac
    12481 attcgatcat gtcgattttg catatgatcc gaagaaacca ttaatccaag atttgaattt
    12541 tgaagtgaaa gctggtcaaa ccgtagctgt ggtcggtccg accggtgccg gcaagacgac
    12601 attgatcaat ctattgatgc gtttttatga cgtagacaaa ggagcaataa ggattgatgg
    12661 aatcgacacc aaatcaatga gtcgcagtga tgtgcgttcg ctatttggta tggtcttgca
    12721 agatgcatgg ctttatcaag gaacgattgc agataatatc cgcttcggaa agcttgatgc
    12781 gacagattat gaagtagttg atgctgcgaa aacagcaaac gtagatcatt ttatccgaac
    12841 gatgccagat ggatatgata tggccatcaa ttctgaggga gacaatgtgt ctttaggaca
    12901 aaaacagttg ctgacgattg cccgagcagt ggtctccgat cctaaaatct tgattttaga
    12961 tgaagcaaca agttcagtag acacccgttt agaagcgttg attcaaaaag caatggatcg
    13021 cgtgatggag ggacggacaa gtttcgtcat cgctcaccgt ttatcgacaa tccgtgatgc
    13081 agatctgatt ctagtgatgg atcaaggtca gatcattgaa aaaggaacgc atgagagttt
    13141 attggcacaa ggtggatttt atgaaaaact gtataacagc caatttgctg aggaagcaga
    13201 ataagtcata taagaataaa acagtttaaa acttattttt tgttctctat tcttgataat
    13261 ggtaaagtaa agttatcaag aaaagtgagg acacggagat ggaacagttt ttaaatgaaa
    13321 aaattactga agccaaaaga gaagttgatc gtttaacgca cgtctgtcag acgaagcctt
    13381 ttgattcagc tgattttttt gaaaatgagt ttcaaatcga acgcttggca gcacaaatag
    13441 aagtgtacga attaatttta aaaaaagtaa tagaagaaaa tatagatgta caataaaaac
    13501 aggtaaaacg tcagttacca gatactgtaa atagacatct ggcctgagca ggttttacct
    13561 gttttttttc ttatgaaata aatatatgct atgatacctt tattcaatag gattagtttc
    13621 tacaaaaaat gaaaggagaa aaataaatat ggaacggttt atagcatcaa atgccacagt
    13681 gattggtgat gtgacattgt cagaagatgt gacgatctgg tatcaagctg ttttacgcgg
    13741 ggacagtaat tggataaaaa taggacaaag aacgaatatc caagatggta caatcatcca
    13801 tgtcgatcat gatgcacctg tagatattgc ggagaatgtg acggtaggac atcagtgcat
    13861 gctacatggc tgtacaatcg aaaaaggggc gctgatcggg atggggacca cgatattgaa
    13921 tcatgcggtt attggtgaga atagtttgat tggtgctgga tcattagtaa cagaaggaaa
    13981 agttattcct cctaatgtct tggcttttgg tcgcccagct aaagtgatcc gtcctttgac
    14041 aaaagaagaa atacaaaaaa acaaagaaaa catccagcat tatgtcgaga taggtcggat
    14101 gcatgcgcaa ggaaaattca aggagcaaag ataggcagta gcatccataa aataaaaaag
    14161 gatggtcagt ttgagttgac catccttttt tatttggttt agataagaga gcttaaaaaa
    14221 gcttcctttg aaacagatta atttaatgaa gaactgtttt ccatgacttc atcgatcaat
    14281 ccatatgctt ttgcttgttc agctgtcata tagttgtcac gatctgtatc tttttcaatc
    14341 acttcaagcg gttgtccagt gcgttcagct aaaattttgt ttaagcgttc gcgtgtttgc
    14401 aaaatatggc gtgccgcaat ttcgatttca gttgcttgcc cttgagcgcc gccaagaggt
    14461 tgatggatca tgatctcagc atttggtaaa gcaaatcgtt taccttttgt accagctgtc
    14521 agcaagaagc ttcccattga agcagccata cccataacaa ttgtttggac atctgctttg
    14581 acaaagttca ttgtgtcgta aatagccata cctgctgtaa ctgaaccacc aggagaattg
    14641 atataaagat agatatcttt ttcagaatct tgagcgtcta agaaaagcaa ttgggcgatg
    14701 atcgaattag caagatcatc tgttacttgg ccgcttaaca tgatgatacg gtctttcaat
    14761 aaacgtgagt agatatcgta agctctttca cctcgtgaag attgttcaat gactgtagga
    14821 attaaattca taatagagtt cctccttgat ttcgtttaga aatagtgtac cataatttag
    14881 tttctaatac ctaaaatgta gtatacattt ttggtcaaaa aaggtcaaat aaaaaactta
    14941 ggcaaattag tcgcataaac ccgctttatg gtatgataag cagagaaaca aaacaaggag
    15001 gaacaacaga ttgatagttg gtattactgg ccttatcgga gtgctgacag gtgctgtagt
    15061 tgtctatatc ggcatgatac tgcaaatgcg tcacttggaa aataaagaac agcgtagacg
    15121 tgaattggaa ttgaaagtca aagaaatcga gacgctgaat caattaaata aaaagatcaa
    15181 cgagatcttg caaaaacgga caacgctgat ggaagaatat gtcagctttg atgcatttga
    15241 tgattgttat atcacgattg acgattttgc gtatctccaa tcattttcag cgcaaaatag
    15301 tttttatctg ccaaattata ttttagacga gctatttaag aatatctccc atcgaaaagt
    15361 gattttatct ccagatgaaa caatgaagat tggtggatat gcttataaag gcggacgcgt
    15421 gattttagag aattttacgg atagtctgac tgaaatgatc aatgaaaaaa aagctcagtt
    15481 gaagactatg acgcgccagc cgattggttt cttctcgaaa gatgatgttt ggagctgata
    15541 ttttgaagca ttgccgttgc acatgagagc gtggtaatgc tttctttttt tcttaatgat
    15601 acaatagaac tgaacggagt gaagaaagat gttacaaatc tatgcccatc gcggaagcag
    15661 cggcacccac ccagaaaata cgcttcctgc atttgcagaa gctgtacgag taggtgcaga
    15721 tggtatcgaa ctagatgtcc atctaagcaa agatggttat ttgatcgtta tgcacgacga
    15781 agaagtggac cggacgacta acggtaaagg gctgattcga gaaaaaacat tggaagaact
    15841 caaaaaattg aatgcagggg gcaaattcag caaagaattt ccagcagcta aagttcctga
    15901 attgagagaa gtgttaggac tgctcctcca aaaaaattac cgagggatgc taatgattga
    15961 aattaaaact gatcagtatg aatatcccgg tatcgaagaa aaattagccg aaacattaaa
    16021 aagtagagat tggccttttc aacatgcata ttgcagcttt catttggatt ctttggaaaa
    16081 aatcgcatta ctggaaccgg agatacagct ggacttattg atgagtactt ctgataaaaa
    16141 gatccaacta gcagcagaaa ccccttatat agaaggagta catccaaaaa atacttggtt
    16201 gttcgaacat ccagtccagg cagctgattt tccaaaagca attcgtgcat ggacgattaa
    16261 cgatgaagaa gaaatggcca aatgtcaaga actcaaaata gatggaataa taactgattt
    16321 tccggagaaa gctcttcggt ggaaacaatc aacgaaaagt aggtaaaata tggaaaaagt
    16381 attagtgatc gtcggtccga cagcagtcgg taaaacagcg ctaagtgtgg aactcgcaca
    16441 actatttgga ggagagatca tcagtggtga ttcattgcaa atctataaaa atctggatat
    16501 cggtacagca aaaatcaaag aagaagagat gaataatgtt ccgcatcatt tgattgatgt
    16561 gatcgaacct actcaacgtt actcagccgc tgattttcag cattcaggtc gacaattgat
    16621 taccgagatt gcgaaccgag ggcacctacc tatcatagct ggtggtacgg gtctctatat
    16681 ccaatccctt ctatatgatt atcagttagg agcgacagaa gaagcgaatc ctgagattag
    16741 aaaaaagtat gaaacgttag ctgaaacaat tggttcccaa gcattatgga atcagttgaa
    16801 agaaaaagac ccggcagctg ctgagaaaat ccactggaac aatcaacgca aagtgataag
    16861 agctctggaa gttttagaga cgacaggaca tagtatcacg gcacctaaag aagagccaaa
    16921 gcaattgtat gattacctca tgattggatt agatacgaag cgtagtattc tttatgaacg
    16981 aatcaatcaa agagtcgatt tgatgctagc agaaggttta gtagcagaag cgcgtaaggt
    17041 gtatgagctt ggagaagtcc aggccagtca aggtattgga tataaagaat ttttccctta
    17101 ttttgaaggg aaagaaacat tggaagaagc aacagaacaa gtcaaactac attcgagaag
    17161 atacgcgaaa cgtcagttga cgtggtttcg taaccgtttg gatgcacagt ggtttgatct
    17221 tataagtgag ccaaatcaaa aaagtcagat tgagcaaaca atcaaaaaat ggctggaggc
    17281 ggaataaaat ggaagaaaaa gtgatcatcg taggggtaga aaccgaagca aaccagcgtt
    17341 acttttcaga gtcaatggaa gagctagttc agctgacgaa taccgcatca ggagaagtcg
    17401 tattcacaat tacacaaaag agaccacaag tggatcggca aacgattatc ggtaaaggga
    17461 aattacaaga attagttcaa caagcggatg cgcatgaagc ggatttgatc atctttaatc
    17521 atgagctaac tccgagacag agccaactga ttaccgatgc tgttggtctt ccggtaattg
    17581 atcgcgtgca gcttatctta gatatttttg cgatgcgtgc tcgttcgaaa gaagggaagc
    17641 tgcaggttga acttgctcag ttagaatacc tgctgcctcg tttagtaggg caagggaaaa
    17701 cattatctcg tcttggcggt gggatcggaa caagagggcc aggtgaaaca aagttagaaa
    17761 cagaccgccg acatatacgg aataaaattt ttgctgttaa gaaagaattg aaagaagtag
    17821 aagctcatcg agagcgcaat cgccaaaaaa gaaaaaatag cgagattttt cagattggac
    17881 ttattggcta cacgaatgcc gggaagtcaa ctatcttgaa tctattgaca caagcggata
    17941 cttattcgaa agatcaattg tttgcaacgt tagatccatt gactaagaga tggcgttttg
    18001 ctgaaggatt tgagattact gtaacggata ccgtcgggtt catccaagac ctgcctacgc
    18061 aactgatcga tgctttccat tctacattag aagaaagtca aaatatggat cttttgctac
    18121 atgtagtcga tgctagttct ccagatcgta ttttacagga gcagactgtc ttaaaattga
    18181 tggatgaact gaatatgaaa gaaatgccga tactgactgt ttacaataag gcagaccaga
    18241 tcgacccagc gatgttcacg cctacgctat tcccaaatgt attgatttct actcagacga
    18301 aagaaggtaa gatggcgttg atcgaagcaa tcaaacgtca gctgatggaa ctaatgaccc
    18361 cttatacact ttctgtgcca agcaacgaag gacagaaatt aagcgagttg agaagacaaa
    18421 caatggtttt ggacgaagcg tacatggaag aaacaaacga atatgaagtt aaagggtttg
    18481 caaaaaccaa ttcaaaatgg ttaagaaaaa accaataaaa ttttattttt ttaacaatat
    18541 tatttgtcaa attaagcgag acaaaacttt ccatttacgt aactcaaaaa aacttctaat
    18601 ggtgtttggt aatttagtga ttttctaggg atatggtttc ttttggacgc aacggatgag
    18661 atgaatcctt gattgacttg gttgaa
//
LOCUS       DAFLWZ010000053        18340 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000053 DAFLWZ010000000
VERSION     DAFLWZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.053"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(187..753)
                     /locus_tag="L1V38_001942"
     CDS             complement(187..753)
                     /locus_tag="L1V38_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1316491.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(753..1709)
                     /locus_tag="L1V38_001943"
     CDS             complement(753..1709)
                     /locus_tag="L1V38_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBN1316492.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1709..2365)
                     /locus_tag="L1V38_001944"
     CDS             complement(1709..2365)
                     /locus_tag="L1V38_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1316493.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            2735..4753
                     /locus_tag="L1V38_001945"
     CDS             2735..4753
                     /locus_tag="L1V38_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1316494.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    4823..5029
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5180..7594
                     /locus_tag="L1V38_001946"
     CDS             5180..7594
                     /locus_tag="L1V38_001946"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBN1316495.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            7942..9495
                     /locus_tag="L1V38_001947"
     CDS             7942..9495
                     /locus_tag="L1V38_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1316496.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(9876..11660)
                     /locus_tag="L1V38_001948"
     CDS             complement(9876..11660)
                     /locus_tag="L1V38_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316497.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11675..13396)
                     /locus_tag="L1V38_001949"
     CDS             complement(11675..13396)
                     /locus_tag="L1V38_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316498.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13496..14257
                     /locus_tag="L1V38_001950"
     CDS             13496..14257
                     /locus_tag="L1V38_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1316499.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15224..15492
                     /locus_tag="L1V38_001951"
                     /pseudo
     CDS             15224..15492
                     /locus_tag="L1V38_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16164..>18340
                     /locus_tag="L1V38_001952"
     CDS             16164..>18340
                     /locus_tag="L1V38_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316500.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
BASE COUNT         6018 a         3273 c         3704 g         5345 t
ORIGIN      
        1 gtcctgcatc aagtaataag aacagccaat caaaaacagc ttctcatgtt tttgatttgg
       61 ttggacttat taccgcagat ataagctttt gagcaccgtg aataaagagg ttatgaaatc
      121 aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca tatcatttat gttttgcgtt
      181 ttttatttat ctttttttct caatacaata taaaataggc ggctggttct tttggttgat
      241 aaaccgataa ttcagcacat tatatgtttc ctgtggcagt ttggaacaaa aagaatcaac
      301 catatccagt tctttttctc caccttcatg accatagtag acgacaagga tcaatcgtcc
      361 gcgaggcaca agtcgtttca atatttcttc catagctgtg cgtgtagtct ctggcatagt
      421 gatgattgct ttatcacttt ttgggagata ccctagattg aaaatccctg ctttgagatt
      481 ttgttgttca gctatcactt ctcctaacgt ttcgtggcct tgtagaaaca atgagacacg
      541 ttcttctaac tgacgctgtt ctagcctttc acgagtagca tcgattgctt gttgctggat
      601 atcaaaacta tagacatgac cagtttttcc gatgtgttct gctagaaaaa ccgtatcgtg
      661 gccattgccc atcgttgcat ctacgacgtg atcccctggt tgcaagattt cttgcagtaa
      721 tgtatggctg aaatgcaaag cagtttgcaa catcagacgc tcaccttttt ccgtacatca
      781 tattttcctt ggaagctatc tctgcgaaga agttcttcat caattgcatt caagacttcc
      841 cattttttca agctccacat tggtccaatc aaggaatccc acggcgcatc ccctgtcaaa
      901 cgatggatga tgatctcttt tggtatcatt tccagctggt cgcaaatgac attgacatag
      961 tcaggacggc tcattaattg aaggcgacct tcatgatagt cccgcaacat tctcgttttg
     1021 cgcatcagat gcatcaaatg gagcttgatt ccttggatat ctgaatctaa aatggtgcgt
     1081 ctgacatttt ctttcatcat ttctaaactt tcgcctggta atccgttgat caaatgcgta
     1141 caaacacgga tattatgttt gcgtaattta gccacgccat ctaaataagt ttgataatca
     1201 tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg tttgcaatcc aagttctacc
     1261 cataaataca tccgctcgtt cagttcagca aggtaatcaa ctacttcatc tggcagacaa
     1321 tccggtcgtg taccgactga taatcctacg acacctggta aattgactac ttgctcaaat
     1381 cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa aattttggaa ataaacgatg
     1441 tattgttgga catgaggcca tttttgatgc atcatgtcga tttctttctg gaattggatt
     1501 ggaagagggt cttcaggtgc aacgatcatg tctcccgaac cagatacact gcaaaaagta
     1561 caaccgccat gggcaacagt cccatctcga ttcggacagt caaatcctcc atcgatcggc
     1621 accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt aattccaaga atgatatctt
     1681 ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt ctttctgtaa gagttatcta
     1741 tttgttttct tttttctcta tacactggat aagtcaggca cagccaagaa agactgagta
     1801 agtaaccgcc gatgatatca gtaggaaaat gaacgcccag ataaatgcgg cttatcccga
     1861 cacttactat aataaacatc atcagcaatt gaagcaatgt gcgtaaggtt cttttttgaa
     1921 caaaagctgg aagcagaaat agtaaagaac cgtaaagaat catactgcct gctgcatgtc
     1981 cactagggaa actgtaactt gtttcaacta ctaagtgcgc caatgaagga cgctctcgca
     2041 tgaaaaatag tttgatcacc gggttgatga ttccagcaat tacaataaat ccagaaacga
     2101 accaaaatgt ttctgccctt tttttcttat accacatcca taaagccgca caagcaaata
     2161 aaatgatgac ggtaagagga ttaccgaatt tagtcataaa gagttggtag ctgttcagat
     2221 caggataaga agctctgaca atgcctgtaa accactgatc gaaaccagaa agccacgaca
     2281 gatggaactt tacgatccag cccaaaatga aaaacaggac aagaaagaag ctaccagcca
     2341 cctgaaatga tgttttatat ttcatacaat tcctcctttg aagcaatgac ttattatagc
     2401 atttttggtc cagcgaaaaa aacggtaaag agataaaacc aatgtatgat tcctctttga
     2461 ataaccaata ttcttataaa aaaaataact gtaatcggaa agacattttt tggtaatgca
     2521 aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat ccttttaaac aagaacgtag
     2581 acgtaggaag aacttgaaaa tgaacagaag ttgttcatta cggtaaatta caatatgatt
     2641 acaaaaaaca acaaagctct taaataactt ttaataaata ttaagagaag ttataattat
     2701 taataataga taaattgaag ttggaggata gaagatggaa aacattgcaa gaaaagaacg
     2761 gagacgttta gaacagacca aacgttttcg aaaagcaaaa cgaggggcag caatcgtggg
     2821 aactgcgatg gtaggctgtt ctgtcgctgc cccattagta cagccggttc ctgttcaagc
     2881 ggatgaaaca cctgttcagt tcggcgcaag aatcaataca gcggcattta tcacagaaat
     2941 tgctacttat gctcaaccaa tcgctcaagc caacgatcta tatgcatcag tgatgatcgc
     3001 acaagcagtt gtagaaagcg gttggggcag tagtgcgtta tctcaagcac cttattataa
     3061 tctttttggg ataaaaggca gctatcaagg acaaaccgtc tacatggata cgcttgaatt
     3121 tttaaataat caatgggtaa ataaaaagga gcctttccga caatatcctt cttttgctga
     3181 atctttcaat gacaatgcct atgtacttag aaatacttca tttggcaacg gttattacta
     3241 tgccggtact tggaagagca acacgaaatc ctatacagat gcgacagctt gtttgacagg
     3301 gcgttatgcg actgatcctg gttacgcagg caaattaaat aatatcatcg caacttacgg
     3361 attgacccaa tatgatacac cagctagcgg aaacgcaggc ggtggagcga ctacaggtgg
     3421 caataatact ggaagtgcag gtagtactgg cggttcaagc aattctggta atacaaactc
     3481 aggttcagca acttcgacca cttatactgt ccaatctggt gattctgttt ggggaatctc
     3541 aaataaattc ggtatcacaa tggatcaatt gatccaatgg aacaacatcc aaaacaattt
     3601 catttatcca ggacaaaaac tgacaatcaa aggtagccag gaaaatggct cttcgacgaa
     3661 taattccggt aacaatacca attcttcagg aaatgctggt acatcaaacg gaggacaaac
     3721 aactggtgcg aaatacactg ttcaatctgg tgattctgtt tggaagatct caaatgatca
     3781 cggaattacg atggctcaat tgattgaatg gaacaatatc aagaacaatt tcgtttatcc
     3841 aggacaacag ctaatcgtat caaatggcgg ttcttctaat gctggagcaa atactggctc
     3901 aaatactggg aatacaagtg gctctagttc gtccagctca agttcttcta atacagcttc
     3961 aggaacgaaa tatacagtta aagccggaga ctctgtttgg agcgtctcaa ataaatacgg
     4021 aattacgatg gctcagctaa tccaatggaa caatatccaa aataacttta tctacccagg
     4081 acaacaactg actgtttcaa acagtggatc aacaaacagc acgtcaggta atacaggttc
     4141 gtcaaccaat acaaataaca gcagttcagt taatactggc agcagttcgt ctcaaggcac
     4201 ttataccgtg aaagcaggtg aatctgtttg gagcgtggca aataaaaacg gcatcacgat
     4261 ggatcagtta atcgaatgga ataatatcaa aaacaacttc atttatccag gacagcaatt
     4321 gatcgttaaa ggtggaactt cggcaaatac aaatacaggt tcaactactt ctgcagcgaa
     4381 accaaataca ccgaatacgt ctgctacgac aagtacatca tccactggta atacgatgta
     4441 taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac aaacatcata tcacgatgga
     4501 tcagttaatc gaatggaata atatcaaaaa taatttcatc tatccaggac agcaagtgat
     4561 tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca gttactggtt cgaaaaccta
     4621 tactgtgaaa tctggagaat ctgtttggag tgttgctgac agtcatggaa ttacaatggc
     4681 tcaactaatc gaatggaaca atattaagaa caactttatt tatccaggtc aaacgttgat
     4741 tgtagctaaa taaaatagct gttcgaagaa ataacgattg aattccacaa aaatatttgt
     4801 tactataagg ctacttaaat atgacaacac ttgaaaagga agtagtaaaa agactgaagt
     4861 ttcagagagc gcatggctgg tgagaatgtg cacggatgct tttgaactcg cctttgagtt
     4921 gcccttgctg aatacccgag taagcaagcg gcggtgacgg ccgttacaac gttcgaggcc
     4981 ttttcactaa ggtaaaatta ggtggtaccg cgtagattac gtcctataaa aagagcaatc
     5041 tttttatagg atttttttat ttcttttgtg aagtttgaga aaacaaagca aaaggaaata
     5101 aaaataaaca gattctgccg gttttttcgt tatatttata atagaaacaa gtgttttcaa
     5161 tagaacagga ggacagcaaa tgagttacaa tcataaagaa attgagaaaa aatggcaaaa
     5221 atactgggca aaaacgaata ctttcaacac ccatgatgat cctgaaaagc caaaatttta
     5281 cgcactggat atgtttccct atccatccgg tcaagggcta catgtagggc atcctgaagg
     5341 ttatacggca acggatatcc tttcacgtgt gaaaagaagt caaggataca acgtgctgca
     5401 tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa tatgcgctag atacaggaaa
     5461 cgatccagct gagtttaccc aaaaaaatat cgaaacattc cgacgccaaa tcaattcttt
     5521 aggatttagt tatgactgga atcgcgaagt gaatacaact gatccggagt attataaatg
     5581 gacacaatgg atctttacga agctttatga aaaaggtcta gcttatgaag cagaagtagc
     5641 ggtaaactgg gtacctgaat taggaacagt tatttcaaat gaagaagtga tcgatgggaa
     5701 aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg cgccaatgga tgctgaaaat
     5761 cactgcttat gctgatcgct tattggatga tctagaatta gttgattggc cagaaagcat
     5821 taaagaaatg caaagaaatt ggatcggtcg ttcagtagga gcaaatattg aatttaaagt
     5881 ggctggtacg gataaatcct ataccgtatt tacgacacga ccagatactc tattcggtgc
     5941 aacttactcg gttcttgcac ctgaactaga tcttgttaga gaaattacga cccctgaaca
     6001 aaaagctgct gtagaagctt atatcgaaga gacagctaaa aaatcagatc taaagagaac
     6061 ggatcttgca aaagaaaaaa caggagtatt tactggtgct tatgcaatca atccagttaa
     6121 tggcaaggaa atcccaatct ggatcgccga ttatgtatta tcttcatacg gcacaggagc
     6181 catcatggct gttccagcac atgatgaacg tgactttgaa ttcgctcaaa ctttcggact
     6241 agaaattctt ccagttatcg aaggtggaga tgttgaaaaa gctgcttaca cagaagatgg
     6301 tacgcacatc aactctgaat ttctagacgg catgaacaaa caagaagcaa tcgataaaat
     6361 gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa gtcagctatc gcttacgtga
     6421 ctggctattc tcccgtcaac gttactgggg tgaaccaatc ccaatcatcc attgggagga
     6481 cggaacagtc acagctgtcc cagaagaaga gctaccatta cggttgccta agacaaaaaa
     6541 catcaagcca agcggtactg gagaatctcc attagcaaat atcgaggagt gggtcaatgt
     6601 cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg aatacaatgc cacaatgggc
     6661 aggaagctca tggtattacc tgcgttatat cgaccctcat aacaaaaaag aactagcaga
     6721 ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac attggtggag cagaacatgc
     6781 ggtacttcat ttactatatg cacgattctg gcataaattc ttatacgata tcggtgttgt
     6841 tcctacaaaa gaaccattcc aaaaactata caatcaagga atgatcttag gcgaaaacaa
     6901 cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct gatgatgtgg tcgaaactta
     6961 cggtgcagat acactgcgca tgtacgaaat gttcatgggg ccattagatg cttcgattgc
     7021 ttggagcgaa aatggcttag aaggaagccg taaattcttg gatcgtgtat ggcgtttgat
     7081 cgttgatgag aacaataaaa tgcgtgaccg tatcactaca ttgaatgatg gcaagcttga
     7141 taaagtgtat catcaaacag tgaaaaaagt gacagaagac tatgaaaatc ttcatttcaa
     7201 tacagcaatc tcccaattga tggtctttat caatgaagcc tataaagtgg acgctctgcc
     7261 ttatgaatat atcgaaggat ttgttcaact actcgcaccg attgctcctc acatgggtga
     7321 agaactatgg gcaatccttg gaaatgatgg tggtatttct tacgcaccat ggccaacata
     7381 cgatgaagca gcacttgttg aagacgaagt agaagttgtt ttccaagtaa acggtaaagt
     7441 tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat gagctagaaa aagcagcatt
     7501 agccaatgaa atagtgcaag aatatattga aggcaaaaca gtcagaaaag ttattgcggt
     7561 accaaacaag ttagtcaata tcgttgctaa ttaattggct ctttgtcaat aaggactgat
     7621 gagttgtgca aaatcaaatc tgggccagaa tgaacttcat tctgtctcag attttttgtt
     7681 atttcaaatt gattaattga ttgatcaaaa aggttttgat tttcatgttc tcaaacacgt
     7741 tcaatgtctt tttcttctga atggtcttgt aagagatctc tgtaatcatc aaatttttgt
     7801 ctattaatct tagtattttt tgatgtataa actacctgaa attgagagta cataccaaat
     7861 tcataaattt tttattagtg ggactagtga ttgtatggat tttgacgcat aatgaatgaa
     7921 gtatgagaaa aggagagaca aatggatcaa gaactattta ttatcgaagt attatcagct
     7981 aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa gaataatgtt caagctttta
     8041 agcttagtat ttttctctgg tttgcttttt ttcggagctg tatcgttcct atatcgccat
     8101 atgagtgcag tagtccgttc agctgaaggg atgcaaaaat taaataattt gtatcacttt
     8161 tcgtggggag ttggcggaat aacaattgtt gtgcttattg tttttcttct acttatttgg
     8221 ctccgttacc atcaattgtc gcgtcatttc gatcaatggc ttagtcaaag agcacaacag
     8281 tttttacata ataaaccaac ttctcaagat gatgactatc tttattttga gaagacttcg
     8341 acgagtcaag cttttcggat acaaaaaagt gattgccagt tattgctgag atcacttgat
     8401 gatttaccta tctacttagg cgaaagcaaa tcaaaattcg gaatgaacac attccatatt
     8461 tttttactag aaaacgaacc cagatgggaa aaaagccagt cttcgcctgg tggatacctg
     8521 acaactaaga tgagtacatt agtcactggt tttttcctca ttcttttagc tggaacaatc
     8581 tattatggga gatacactca gccaaaaatg tcttctcata taaatgctgc ttctcacatg
     8641 acaatgaact caactaacga tacgcatata caaaagacaa atgaagggtt gttagctgat
     8701 cctaagcaaa aggtaaattt gacaacacaa aagataaatg atctcaaact tgatacagag
     8761 acgcactctc tctatatgac aacagatagt ggtgctaatt gggtatttgt gccgattgat
     8821 tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg ggctgattcc tgaaggttat
     8881 tggatggaca acacatatga tatttccgcc gatttctcat ggtttatcta ttcttctggg
     8941 gatgatgtac gtctgctgac ttcaagagat aatggtaaaa catggcaaac gtctattatc
     9001 acccaatcag ttcagccgat acgttatcga aaagcggtat tttatggcaa cgatggtcta
     9061 tttatctgta catcagccag tgggatgtct gcagaaactt tgtacattta cactactatg
     9121 gatggcggaa tcacttggat aaaaagtgga agtacaatga tcaatcagcc agtacaaaat
     9181 gtcagcttcg ttacaacttc tttaggtttt gtttcgacac gtgaaagttt gttttataca
     9241 aacaacggag gacgctcatt caaagaatca gttctgtcga ttccggaaaa ctatcagaca
     9301 ggggggatag atctttttca atcaccaaat gaagttactc aaataagcgc gaatacgtta
     9361 gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg cagggaaaat gtttgcctgc
     9421 ctcttccgtt caactgataa cggggaaaca tggcaattcg ttcagcaact atcgcaagta
     9481 gaacaaggag attaaagaag agagattgtg agcctgacgt tcagcaccga gtcacaagaa
     9541 acaaattcaa aaaacagctt ctcatatttg ttgaatagtg taactcgtga ttcggagttg
     9601 acaagagcaa caagaagcga ttttgaagta tagcttctcg tattttacaa gatcgtgtct
     9661 tattgccgat aggttgtctc ttgaacaccg tttattcgta aaaagggatt gtgacaagtc
     9721 ttttgtcact acttaccgaa cgaaactgaa ggagctatcc aaaaagtatc attagtatta
     9781 ttctttgtgt ttctagtggc accactagta catttaaaaa agctatcgat catggactaa
     9841 tcatacatga tcgatagctt tttagataat gtttgttacg ctatctgaaa ttgactatta
     9901 taaagactgg cataaagcgt tggtgattgg agtagttcag aatgtgttcc tttttcgacg
     9961 atatcgccat tcttcattac aaggatcatg tctgcatttt caatcgttga caaacggtgt
    10021 gcaatcacaa aacttgtcct atcttttgtc acagcttcca ttgcttgctg aatcaatgct
    10081 tctgttcgtg tatctacgct agaagttgct tcatctaaaa taacgacagg aggattcgct
    10141 agaatgactc gagcaattgt caataattgt tgctgtcctt gagataacgt gccgttttcg
    10201 ctagaaatga tcgtatcata tccgtctggc agtgttcgaa taaagtgatc acattgtgcg
    10261 atttcagccg cttcgataat ttgttctctt gtggcatcca ttttcccgta ggcgatatta
    10321 tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa ccatcccaaa agaacgacgt
    10381 agttctccac gtgaaagctt ggtaatatca agaccgtcga attcgatctt tcctttattc
    10441 agttcataaa aacgcatcag cagattgact aaagtcgttt ttcctgcacc agttggacca
    10501 acgatcgcta ccgtttgttt tggctttact gaaaaatcga cttgattcat caatatttta
    10561 tctgatgtgt aaccaaactg tacatttttg aaagctattt ttcctttcgg ttgttctaaa
    10621 agtcttgcat ctggaaggtc tggaatttca tctgtttcat ctaatatctc aaatatccta
    10681 tcgattgctg ccattgcgga ttggatcgag ttgatcacat aagaagcggt agaaattggt
    10741 tcagaaatct gattgatgta ctgaagataa gcttgtaaga agccgatcgt cacaccacct
    10801 gatagaacaa gcatagcacc gaataccgca cttatgatga aggcgagttg attaatgaaa
    10861 cgaatggccg gatagatagc acagttcata aattgagcac gtttaaaagc gttgtattgc
    10921 tttttattta cttcgtgtat agcagcttct gcatgagctt gctgattgaa tgttttgacc
    10981 actagattac cagctaagat ttcttccatt cgattattta aaacacccag ttcatactga
    11041 ttctgttcag aaatctgttt gtttttgttc gcaatcttag ttgtaacaat tgaactgcca
    11101 acgatcagca ataagacgag caaagtaagc ttgctttcga tataaaacag catcagacca
    11161 gcagcagcta ttgttacgac agaagtaaaa aattgattga tacctgtcaa taacacttga
    11221 gaaagttgat tgagaccggt agttgtccga ctaatgatgt cacctacttg atgattgtca
    11281 aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt cttttcgcac cctcaatgtg
    11341 atcttttcgc ttaacgctgc cattgtccgt tcctgaataa atgaagtgat gctgcttaag
    11401 actgaacagc cgatcagcaa taagacaggg aacaacaatg cttgtttgat atcactgaaa
    11461 gaaagctgtc caatacctgt ttttcttatt tctgataaga gatcatcgat cccgattccc
    11521 atgatcaagg gcatggctac gactaatagg ttcccgaata aactgcatag aaacaatccg
    11581 taaaaatatt tatgttcagg tttgatcatt ttccaaaaac gtatcaaagc acgcgtgttc
    11641 aacgtttttt tcttttccat cgtatccctt ctttctatat tccttgtgat tttgcaaact
    11701 cctgataagt ttggcaatta gacagtagtt cttcatgagt accttgtcca acgatttttc
    11761 cttcatctaa aacaatgatg ttatctgctt gttggattgt actgaggcgt tgagcaacaa
    11821 tcacgagagt tttctccgac atgtgtttat gaagggctgc tcttaatgct gcatctgttt
    11881 tatagtctaa agcggagaaa ctatcatcga atacatagat ctctgctggt ttgatcaacg
    11941 ctcgagcaat acatatccgc tgtttctggc cccctgaata attagaaccg ccttgagcaa
    12001 caaagctgtc caatccgtca ggaagggtgt ccactagttc ttctaattga gcgatcttga
    12061 tcgctttaga caactcttct gttgaggcat attcatttcc catctgcaag ttgcttaaaa
    12121 ttgtcccgct gaataagaaa gccttctgag ggacataact gatgtgggag cggatctgtt
    12181 cttgagtcat ttgagtaaga ggaataccac caagggttac ttttcctatc gtagggtcac
    12241 taagtctcaa gagaagtttc gccaaactac tttttccaga tccggtcccg ccaacgatcg
    12301 ctgttgtttt tcctttaggt attgtgaaat caatatcttc tagaactgga tcagagattt
    12361 cagtatattt aaatgtgaca tgttcaaaag cagctgcatt tgtctgatca aaggttggtt
    12421 cagctactgt tttgatcgtc tcttcctcaa tttcgatctc tgcttgcagt atttcttcta
    12481 tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa taccatagct gcgatcatca
    12541 agtaagcaag tgtcagcata gagtattcga ctacagcagt cacgacaccg atttgtaatg
    12601 ctccttctgc tacaagattt ccgccaaacc acaaaataga agcataaacg attcccatga
    12661 gcaaaaaagc aattggagtg acccaagcaa atattcggtt cactttgatc atttgattag
    12721 catagtcagc aaagctctta ttcgttcgct tttcttcata tgattgatta tcaaaggcac
    12781 ggatcatatt aatcccagta aagaattctc tcaatgtgat ggtgatccga tccatttttg
    12841 gctggatact caaagataaa ggtgcccctc gtttcatcag tcgataaaca atccatacat
    12901 aaaaaacaac agagatcaat gtaacccatg ttagtaatag agaataacga aacatcatga
    12961 gaatggtgaa aacgcaaata accggtgctg gtaagatcat ttggcaaaat aaaacaatca
    13021 tttgctggac attatcgaca tcattcgtca ttcttgtcaa aagagatcca gaactaaaac
    13081 gactgatatc cttcattgac agctgttgga atttacggaa atatttctcc cgcgtttgga
    13141 atccaaacct agcggaagcc aatgctgaaa agtaactaga ggcaactgca gcgattgttc
    13201 ctagaaacgc tacaagcagc atttcaactc caattttttt tataactgag gcttcgccac
    13261 ttgctatacc tgtgtcgatc agctttgcta ctaattttgg tacacctaat gtaccggcga
    13321 tttctaaaca gatcatcaca aaggtaagga gagcgagtcc tttgtttttc tgtaagaatg
    13381 tttttaagat agacatatta ttcctccttt tttcctgata cttttcgatt ctataccttc
    13441 aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa aagaggtgag aaaaaatgaa
    13501 aaaaatgtat acgattggcc aagtatcgga actatttgat ttgccaaaat caacgatccg
    13561 ctattgggat gaacaaggat taatccgttc aagtagacaa gaagagaatg attatcgatt
    13621 gtttgatatc gatgatattt ttatgcttta tgatatcgtt ttttatagaa aattagatat
    13681 accgatcaaa cagatgaaga atttatatgg aaaaacattg acggagttat atgagacact
    13741 tgatgaaaca gaaagaagaa tccataaaga actggtggtg atgaaacaaa aacaaaaaga
    13801 gataagggag caaaaaaaac agttgaaatt gatgatcgat acaaacgagg aagaatttcc
    13861 tgtagaagag atcccttttg actgtatgat ctcaacggag tttgaagata ttgtggaaat
    13921 caaaaaattt ctacctaact attcaagctt tgggatgatg agtatgccag cttccagttc
    13981 acagacgatg tatggatttt ttatcgaccc tagtgaagta catttattta ctcaagacgt
    14041 gatttgggag aaaaaagata cggctgttta tcgtcgattc ttattgaaat ccgagatgaa
    14101 ccatgcggaa cgtaataata ttttagaaat cagagaaaga atgtatgaaa aaggatggaa
    14161 aacaggagaa gtgatcggcc agtatctatt gacgaatacg gatgaaaaca atatcagaac
    14221 tgaatattat catgcatgga tagaaatgaa aaaataggaa atatgtgttt aagataactc
    14281 gaaaatgatg gttgttttag ttataaagaa aaattttctg gttcgattac gggtttaatg
    14341 tgggggatta ttagtcgtgg atagatagaa ttttagtttt ttagaggaaa tatgtcttta
    14401 aaaatggaat ggttgcaatt cttagcgata tatacgatgt aattgtcctc ttaaaaaagt
    14461 atggaaaaat aattgtattg ggtgttatgt ataattcatg gtgaactgag actaatgaga
    14521 agaaaaattc atattgttat gagtgagatt gtatcagatg agaatgataa attaaatagg
    14581 tgcataaaag cattacactt aaaatacatt gttgcttaca ttattacaat atgttaataa
    14641 ggcaaaaata aatagatgga ttgaataaac atatttttta atcaaatagt ccctactgtg
    14701 actttcctca gctatcggtg atactaccga tagcattttt ttgcttataa aataattata
    14761 agtatttaga gatttttctt ctaacattct tcaaacaaga aaaatcacaa aggttattgt
    14821 tatttttata tattcttttt aagaatgatt gtttttttat agaaatttta aaaaataaaa
    14881 cacgttattg atggatagtt agtttgttat ttggtaatat tatagaagtt gactggtagt
    14941 gatttatttt tcgtcgtttt ataaaaatgt tattttttgg aaaaattcac aaatatgtaa
    15001 cgaatgtttt tctggaattt gctgtgttaa aaagcagtat gactaatata aatactattg
    15061 tcatttatgc aattttttat ggatagtaat tttagagggg aatcaatgaa ggaagaatag
    15121 aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata gcaatacatc ttcaagcttt
    15181 aaaattcgag agaatcatct tggtagtgga atcaactaca acaaaaggat taaaccaatt
    15241 aatagataga attaccaatg gaaaaataga aaaggtagtt attctataca aaagttgttt
    15301 aattcgcttc ggttatgaac ttagtgaaac cctttgcaat atatggtaca gaatatagaa
    15361 attattgaca ttacagaaaa tgatgaagat ttaatacaga ttgtcactat ttgtagatac
    15421 cttttacaag gaaaccgagc caataaagct aagaagatga ttaaggagtt gatggaagac
    15481 gatacaagtt aagaaagtga aactacgccc aaataaagag caaaaagagt aattggacgt
    15541 ggaaaatgca agaaatgaac catcgattcg gtggacagtt tattagtaat gacggtttga
    15601 gaacatccat gacgagaatg aaggaacatc ctaaatgcgt ttagttgaac caagtgccaa
    15661 ataatatggc caaataagcg atcagttatc gatgaatccc aagtattcta aactatatat
    15721 tcattttgat gctaagcatt gatatatttt tttgggattg atgaaggtta accaatacag
    15781 ggactcactg atgaaattct agagtctgac cttggtatca acgatttagt gattgtttct
    15841 aatggaaaag tataaaagta tataagtaca ttaacaaaat aactattagg gttacgctcc
    15901 agcttgtgca aggcactggc aggaggaatc gtgaaatcat aattatggtt aagccacacg
    15961 gacaactaaa agtcatacaa agctatcgaa tcaatcaaca gaagacaatc ggcaatcatt
    16021 agctttgttt acagcttaca ttgcaacgct tgagttgaac cgaaaatacg agggaggtaa
    16081 cgcagccatt ttgagttggg gaatcttttt agaaaattat cgggtacctt gttgtttagt
    16141 caaaattata agggggagta atagtgagga acaaatttca taaactgtta agtatgtttc
    16201 tagttatgct tattgtgatc aatcaatttg ggaacataac ggttctagct gagtctttag
    16261 cagaacagcc agagcgttcg ctgacgatcg aagttgatca agaggaggct gctttgggtg
    16321 agcagttcca gttgcgagtc agaggaacac cagacctgct aaatgcattg gtcattgata
    16381 agagtgagga tttgattgaa ggggaagtga agcaactcaa tgattacgaa cgtctgatta
    16441 cttattcttc ccagcattca ggtaaatacg aattgaccgc aagaagcggt gatattcaat
    16501 caaatacggt ctcaatagaa atcagtgtac cagaagaaag cacaagtgag tcttttaatg
    16561 taccagaaga aagcacaagt gaatctttta atataccaga agaaagctta agtgaatctt
    16621 ttaatgaagc cagatcatct gagccatcta taacgcagga atctcagatt gaaagacaag
    16681 aggagctctt gaattatgac atcggcatct ctgctgagcg ccccactttg ccgagcaggc
    16741 atacacaaac gttaaaggga tacattcaag gaggcgctgg cgatattctt gaagaatatg
    16801 gggagatggt cgtacgagtt cctagagcat cgattggctt aattgagttc attagagtgg
    16861 aggtcgctga tgattcacct ttaaagccac tggcatttta ccaagaaggc acagacgttg
    16921 tttttccatt tacctttgat tatgaaggat taaatgaagc cgctcagtcg tatacattca
    16981 gtatcacgtt tgaagttgct ttctttcaat caggcggtac tgagccaaat aatgactttc
    17041 aagtgagtct tacttatgct gagcgagcag caaacacgga attttcaatt acgcctattc
    17101 cttcatcaag acccattttt tcgaaattat actatggctc tagagaaatc gacagccaag
    17161 gaaatcttgg gaatctgctg attgacgggc aagacgtgac caacagtaat aaatttattt
    17221 tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt ggttaccgat gtactaccgc
    17281 aaggaacaac tttggcaccg aatccgacta catggagttc cactggaaat agagaaccta
    17341 tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg tgaagcaaac gttagaactc
    17401 attatgtttc cgaggaattt gtggacaaag tatcttttaa taaggaaacg aatacacttg
    17461 ttgtggactt tggtaatcta gcagagggtc aatcgtattt tattgaatat gctcttgaag
    17521 tgaccgatgt cgacttgttc aatgaaggaa gacaagagga tgggttttct cggaatcgag
    17581 cgagtatgac ctacaataat caggtaatga gccgagacta ccgcttgaga atccctgaaa
    17641 gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa aaatgttatc aatctcaatg
    17701 aaaatgaact aacgtatact ctgcatgtct cgatgttttc tggaacaaga aatacgcttg
    17761 ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc atttctatca gatattccct
    17821 ctttcattga tgccgaagtc aataatggaa tagttcgttt cagtgcgaat aatacgattg
    17881 gtggtccgac aagttttacc ctctctttta aggtcaatgt agaggcgtat gcggtcggcg
    17941 atcaaatttt aaactttgca acgcttgtga atagtgacaa tcgattgaat acgagtactg
    18001 taagaacaag gaaaatcgat gggcgtatta aagtaattaa aactgatgag aatggccaaa
    18061 ggctggcagg agcaaaattt gaaattttat caagcgattc acaagtgata caagaaggta
    18121 taacggcaga aaacggagaa tttttaagtg aaccgcttcc tgtaggtagc tatcaagtcc
    18181 gagaaacaga agcaccggaa gggtatcttt tagatgcgac ggtacatgat gtttttataa
    18241 atgaatactc catagaagaa gtgacgttaa ccattgaaaa catccttgat acgggtggtg
    18301 ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
//
LOCUS       DAFLWZ010000054        18328 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000054 DAFLWZ010000000
VERSION     DAFLWZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.054"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            19..540
                     /locus_tag="L1V38_001953"
     CDS             19..540
                     /locus_tag="L1V38_001953"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316501.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            541..858
                     /locus_tag="L1V38_001954"
     CDS             541..858
                     /locus_tag="L1V38_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1316502.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1015..1179)
                     /locus_tag="L1V38_001955"
     CDS             complement(1015..1179)
                     /locus_tag="L1V38_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBN1316503.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1282..1803
                     /locus_tag="L1V38_001956"
     CDS             1282..1803
                     /locus_tag="L1V38_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1316504.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1790..2263
                     /locus_tag="L1V38_001957"
     CDS             1790..2263
                     /locus_tag="L1V38_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBN1316505.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2270..2428)
                     /locus_tag="L1V38_001958"
     CDS             complement(2270..2428)
                     /locus_tag="L1V38_001958"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBN1316506.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2521..3282
                     /locus_tag="L1V38_001959"
     CDS             2521..3282
                     /locus_tag="L1V38_001959"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1316507.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3502..4821
                     /locus_tag="L1V38_001960"
     CDS             3502..4821
                     /locus_tag="L1V38_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1316508.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            4837..6057
                     /locus_tag="L1V38_001961"
     CDS             4837..6057
                     /locus_tag="L1V38_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1316509.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6092..6769
                     /locus_tag="L1V38_001962"
     CDS             6092..6769
                     /locus_tag="L1V38_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBN1316510.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6766..7962
                     /locus_tag="L1V38_001963"
     CDS             6766..7962
                     /locus_tag="L1V38_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1316511.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7977..8300
                     /locus_tag="L1V38_001964"
     CDS             7977..8300
                     /locus_tag="L1V38_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1316512.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8304..8639
                     /locus_tag="L1V38_001965"
     CDS             8304..8639
                     /locus_tag="L1V38_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1316513.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8636..9031
                     /locus_tag="L1V38_001966"
     CDS             8636..9031
                     /locus_tag="L1V38_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316514.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9028..9399
                     /locus_tag="L1V38_001967"
     CDS             9028..9399
                     /locus_tag="L1V38_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316515.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9415..9975
                     /locus_tag="L1V38_001968"
     CDS             9415..9975
                     /locus_tag="L1V38_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1316516.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10102..10413
                     /locus_tag="L1V38_001969"
     CDS             10102..10413
                     /locus_tag="L1V38_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316517.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10437..10628
                     /locus_tag="L1V38_001970"
     CDS             10437..10628
                     /locus_tag="L1V38_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316518.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10628..14473
                     /locus_tag="L1V38_001971"
     CDS             10628..14473
                     /locus_tag="L1V38_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1316519.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14474..15346
                     /locus_tag="L1V38_001972"
     CDS             14474..15346
                     /locus_tag="L1V38_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBN1316520.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15343..16392
                     /locus_tag="L1V38_001973"
     CDS             15343..16392
                     /locus_tag="L1V38_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316521.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16396..17220
                     /locus_tag="L1V38_001974"
     CDS             16396..17220
                     /locus_tag="L1V38_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316522.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17238..17783
                     /locus_tag="L1V38_001975"
                     /pseudo
     CDS             17238..17783
                     /locus_tag="L1V38_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176405.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
BASE COUNT         6339 a         3150 c         4128 g         4711 t
ORIGIN      
        1 gattaaggag gaagagtaat gcatatagga gataagatac ataaattgag acggcttaat
       61 aacgaaacaa tgaacgactt agttaaacaa accggactgt caaaatcatg ggtatctgat
      121 attgagtctg gaaaaaagca acgcgctgac tttaataaga tatgtgcaat agccaaacat
      181 tataaagtta gcttagaata ctttcaggat gattatttgg atagtgatga acacgaggat
      241 attattcctt tgacagacga aacaagagtt aaatcagtga aatcgcttga acaaagccta
      301 aagtatctga ataacaaaca agaacctaac cttctagaga tcaaactaaa agatactgac
      361 tcagtaccag aggtttatta caaaggtcag aagttagagg gattgataga tgtaagctat
      421 cactaccata caacaactga tgtggtagct ggttcaacaa acgacatcaa tatggagtac
      481 ctaggtgaag taactaagta tccagatata aaaacaatcg gacacaagag agatgtgtaa
      541 atgaaagaag ctagacctag agacgagata gacaaactat acaagaccaa acgatggcga
      601 gacctaaggc aagtagtaat agctagggac ttcggcatgt gccaagagtg caagcgtcga
      661 gggcggaaca caaggggcac gatcatccat cacatagtcg aggcgaggga agacctgtca
      721 ctgttctggt ccgtagataa ccttgaatgt atctgtgtag cttgtcacaa cagagagcat
      781 ccagagagat caggcgggaa gaagaaacca aaacctaaat cacatatcgt taaaatgtat
      841 tcaactcctg aaagataagt ttgcagcgaa atgaaggtag cccccctact ctaaaagatt
      901 aaagagtaag gcttgagaag aacggtgctg tccttccttc gtaaaaagac cgcttttcaa
      961 gttttttgga gaaaaaggaa aaagccgacc aatttaagcc ggctttggac gaagctattt
     1021 cttagtccat ttgtttcctt tttgagaagt aggaggtaat cggtcgcctg gatcaatttt
     1081 tacttctcgt ccgccttgga catttccacc acgaggtccc acttctttat aggttccttt
     1141 tggtttattg tcttcgccgg gtttatagag ttctcccata ggaatccctc cctaaaaaaa
     1201 tttcggcaca gcactgccga taacttaatt ataaggattg tgataacgat ttcaatatat
     1261 cttttgaaag aaggtgatat tatgccgcaa ccagcgaaga gtgcaaaatt acaattatta
     1321 aacggaaacc caaataagaa gaataccgaa gaactccgca agcgagcggc cgcagaagac
     1381 aaattaaaaa tggctactga caaaatcaaa ccgccgttat ggctagattc gctaggaaag
     1441 gatacctttg agtttatcgc tgatgaattg ctgtctgtgg atttaatcag taatccggac
     1501 gtccatacaa tggctctcta ctccaattgg tattcgcaat acgtttcttt agaaaaacag
     1561 cttcgaaaac tacaacgaga gtacaagttg aactatgcgc ttgcgaaaaa ggaggcagag
     1621 gcgagaggtg agccgtttaa tgaacctaat gaattaattg gtaatccgct ctctcggcag
     1681 atggatacag cgtcgcggaa tctccgttct tttggcgctg atttaggact atcaccagca
     1741 gccagagcta agttagctat taagatggct gatgatggtg gtgatgacga tgacgacttc
     1801 taatattttg gatatgtcct acacagaacg tgtggactat tggcaaagct atcttgagga
     1861 gcaagcttct tggggtggct ttttaaaatg tccatatccg gaattgttaa ctacttggta
     1921 tgcggaacga ttaatcgatg gaagcatacc agccagcaaa gaaaatattc aagctgctaa
     1981 acggcatatg cgtgatttgc agcgccaagg aacagatgat tttccttgga tctttgacga
     2041 agaaaaaggt caccggccta ttagatatat cgaaaaaaaa tgtaaaccaa ctgaaggcga
     2101 ctttggttcg tttgttttgc aaccttggca gcatttcata attggatcca tgtacggatg
     2161 ggtacatcgt gatacaggag agcgtcgctt ccgcgaggct cttatttttg ttggacgtaa
     2221 aaacggtaag ttttgccgtt taaaaatcgg gcaaaatcgg tgaaaacctt tatttttggc
     2281 tttcttttag taataattcg atagctttat caagcaattt agacatagga accatagttt
     2341 cttccgacat tttttttaat ccttcgtata aatctttatc aattgcgtta gaaattctaa
     2401 ttctgttttt tagtccgtat ttgtccatgt gtgacactcc tttttatttt actataacat
     2461 ccgattccac cgcttgcaac taccatcaat tgatggtagt atataaaaga ggtgagtaga
     2521 ttgaaaaaat acattattta caaacactta aataaaataa atggcaaaat ttatatcggt
     2581 gtcacaaatg atattggcag aaggtggagg agcggtggga ttgaatataa accaccaaag
     2641 aacgaaaccc aacaccacag aagtttttgg aatgcaatac aaaaatacgg gtgggaaaat
     2701 tttgatcatt tgattattga agaagactta acgatgaaag aagcttttga gaaagaaaag
     2761 ttttatattg aactttatga ctcaactaat aagaaaaaag gttataacat cgcaaaaggc
     2821 ggaaatggcg gaataatata taaagttcac cccaaaggaa tgctagggaa aaaacaatct
     2881 aaagaatttt cttcaaatca cagtaaatgg gcaaagaacc ataagaataa ttgtatgaca
     2941 aacggtgatg ttgtatgggg tgttactcac gaacacccaa aaggcatgtt gggaaagcac
     3001 cacagcaaag aatcaattat gaaaaagaaa gcatatagtg gtgaaaatgc tgtaacctca
     3061 aaaccaattg tcgcaattga acgggatgga actaaaagag aatttcacag cgctaagctt
     3121 tgcatggctt actattcgat tagtacatgt gttttttacc gacttttaaa agatggcgcc
     3181 ccttatgtga taaatcctaa agcgaactac agaaataaag aaaaaatatt agctatcgaa
     3241 ggaattatgt tcaaacataa agaagatacc gaggtaagtt agtagattgc gaaaggttac
     3301 taactaccgt aacgcgtagg agttgaataa atataatgct cccaagagtg tccgacagca
     3361 gataatttgc tgaaaatgta cgctaaactg ggccagaact gactgaccga tgaaaatgag
     3421 ggtgacctcc agagtgcgag ataaaaagct cgcagataat aacaatcgaa aacatcacta
     3481 atttcaggcc tttccacata catggtcgct tatgatgatg aacaaggcgc caacgtttac
     3541 gtattggcaa atgctcgtga tcaagcaagc ttgttgtttg ataaggccgc agaaatggtc
     3601 aaacaatcgc cggcgctctt taagaaattt ggtaagccta aacgatcaag tattaattat
     3661 gctcccgcct tttctaaaat ggaaccacgc gcctcagata gccggaaatt ggatgggcta
     3721 aacactcact ttggtatttt tgacgagatc cacgagttta cgaattacaa tctgatcaac
     3781 gttatcaaga aatcaagagg aaccagaaaa cagcctctga tagtttatat cacaactgct
     3841 ggatatgtat tagatggtcc gttgatgtct tattttgagc aaggtgtgga ctgtttggaa
     3901 catttggaag atgacatcga tgaacggact ttctattatc tggcaaaact tgacagtgcg
     3961 gaagaggctg atgacccaag attatggatc aaagccaatc cgaatatttg tctaatgaat
     4021 tttgttggca tgctagatga ctatgttaag gataaaaaag atccaaaaga atatgctgac
     4081 tggattacca agcaatttaa cttgttttcc gatatcgatg agctgtcatt tgtcgatatg
     4141 cctaccatta aacgaaacaa taaaaccatc gatattgaaa cgctcaaagg taagaagtgt
     4201 gtcggtggtt ttgacttgtc cgaaacggaa gactttaccg cagccgtttt agaatttccg
     4261 cttgaaacag gcgaggtatt cattttgcaa cacacatgga tcccacaagc tagatttgat
     4321 cgagataaca atcaagagcg tatcaaagcg tgggagaagg tgggagatct aacgattatt
     4381 cctggtgatt acgtcaatta tgaatacgtc ttaaattggt ttgtagaaaa ttcgaaaatc
     4441 tatgacattg taaaaatcaa ttatgacaag gccaaggcgc tacgattaaa taaagaacta
     4501 gaaaatgcag gatttgaaac caacgagatt cggcaagggt ttctatcatt aggtgggcca
     4561 atgcaaaact tcaaggaaat gctattggac ggtaaggtga ttttcaacaa ttccaagctt
     4621 taccgatggt atctatccaa cgtcaagctg gtgatggatc gcaactcaaa ctggatgccg
     4681 tctaagcagt ccaagagtag aaaaatagat ggttttgcag caagtttgaa cagccacgcc
     4741 gaagtgttga atatgttggt taatcctgtc ggaaccggga aagtaaccta ttactcgatt
     4801 tccgatttaa tgaatatgta agaaaggtgt ggaggaatga gtattttaga tcgtttgcgt
     4861 tcttttggcc gagcgaagcc gaaagcgagc aaacaagagt attttttgaa tgacccggga
     4921 ttgataccgt atttagtcgg aaaagatgaa atatcagaag ggattttttc cgtaattagc
     4981 cgtgtatcga acgtttttgc gtctctccct ctcaaaatga tagatgcgga gtttggccaa
     5041 ccggacgact gtcctgcata caacttgttg agcgaaggcc ctcgatattt tacaaagttt
     5101 gattttttcc gggacgtgga agttttgaga aactaccaag ggaatgcgta tgtgcagatt
     5161 ttccgaaata tcaatggaga agtagcagat atggcgttaa taaaacctgg tgcttgccat
     5221 ccagtgattg atatggatag cggggagctt tactaccaag taactgcgac tgacaaaggc
     5281 agttataagc aagttattta tgtacattac atggaaatgc tccactttaa acaaccgagg
     5341 tttggtggct tggaaggtac agaccccaca aaagtattaa cgaataccct cggatatgat
     5401 cgagaagtcc gaaaaatctc tttaagtcag cttaaaggag gtaatgaagg gctaaaagtt
     5461 aagtttgcta gcaatgtgga tgaagaagct aaaaaagcta cagttaaaaa cattgctgat
     5521 ttttatcgac aaaacggtgg actacttgtg gaagaaaacg gtgtagaaat cgaacgttta
     5581 caacgagagc tggtagacag caagctttta gatactgata aagtatctcg ctccagaatc
     5641 gcgatggtct acaacgtgcc ggaacatttc attgggagta accagtcgag ttactcttca
     5701 caggaacagc tcaatatgga gtttttgaca tacaatctag taccgaccgt taatcaatat
     5761 gaagcggaac taaataagaa aacactatcg agaaccgaaa aagcaaaagg ttatcgatat
     5821 aagtttaatg tcgcaagttt gctaagagct gacactcagg caagggggca attctatcaa
     5881 atcatgcgac gaggcggagc atactcagcg aatgatgtcc gaagatttga ggacttgcaa
     5941 ccgataaata aaaccggtat ggatgattat catatttccg gagacctata tccaatcgat
     6001 atggatccaa cattaagaaa aacaaactcg tctaaaagcg tagccgaaaa cggttaggct
     6061 tttttagttt gcaccgaagg gaggtgaaag gatgaaaaaa gtgacgttaa gcggcgatgt
     6121 cgtggataac gataccgcgt ggttatatga ctggtttggg attgattgta tctcaccagg
     6181 gaaaatttct gccgctctta cagaagcagc gggggatgaa gtagaacttg atatctcatc
     6241 taacggtggg gatgtcctag cggcaagcga aatatatacc gctatccgtg cctatccggg
     6301 aaaggtatcc ggaaatgttg tgagtattgc agcaagcgct gcaagtgtaa tcgcttgtgc
     6361 ttgcgaaccg cttagaatct cgccaacagc acacatcatg attcacaacg catgggtgac
     6421 cactagcggc aacgccgagg aattaaaagc caatgcggaa atgttaagca gtgtggatga
     6481 gtctatcgtt aatgcttacg agatcaagac aggactcgac cggaaaaagc ttgctgattt
     6541 aatggcaaaa gatacttggt taaacgcaca aacagcagtg gcggaaggtt ttgcggatga
     6601 aattatgttt gcagaagcac cagtaacggt actcaatgcc tctcaaccgg ttattccaaa
     6661 aaacgcggta actaagttga aaaatctaat actcaaagcg gaaacaccgc aagaagaaac
     6721 gctcttgcag aaaaaactaa aagccttaaa tggagggaaa aacgaatgaa tttagaacaa
     6781 ttaaaaaatg cgtgggtcga ggcgggaagt aaagtctctg atttaaacgc gcaactcaat
     6841 gcagcattgg ttgacgatga aaaaacagaa gaagatgtag taagtttgca agcacaagta
     6901 aaagcagcac gggctaaacg ggacggattg aaagagcaag tggcaaatat ggaagccgaa
     6961 caagtcttaa acgtcaaaaa agaaccatta gataaaaaag atgaaaactt gaaaaacaag
     7021 tttatcaaag actttaaagc gatggtcaat ggtgatcctg ctattatggc tactttgaca
     7081 tctaatacgg atgaatctgg taatgctatc ggattgacta ttcctgtaga tgtgcaaacg
     7141 actattcata ctttggttcg tcagtttgac tctttgcaag aatacgtaaa cgttgaaaaa
     7201 gtgaccacta ctagcggttc tcgggtttat gaaaaatggt ctgatattaa cccactgacc
     7261 gctttggata ctgaagacgg tgaaatccca gcaaatgatg atcctgcact ttacttgatc
     7321 aaatacttga tcaaacgcta cgcaggtatt tctacagtaa ctaacagctt gctaaaagat
     7381 actgccgaaa acattttggc atggttgtct aactggatcg cgaaaaaagt agttgttact
     7441 cgcaatacaa aaatcttggc agctattgat ggaatcaaag cagcgcaaaa gaaagatgtt
     7501 acagatgttg atgggattaa agatatcata aacgtccaac ttgatccagc tatcgaagct
     7561 acatctatgt ttattacaaa ccaagatggc ttcaatgttt tagataaagt gaaacgtgct
     7621 gatggatctt acttgttaca aaaagacgta gcttctgcaa ctggatatac cttcttaggt
     7681 aaaccaatca agaaaattgc ttctcgtttc ttgccaaaca aaggtacgca agctactcct
     7741 aaatatccac tgtatattgg tgatctgaaa gaagctgtta cattgtatga tcgcgaaaac
     7801 atgagcttgc tgacaacgaa tattggcggg ggggcttttg aaacagacac caccaaagta
     7861 cgggttatcg atcgatttga tgtgcagtta gtcgatgatg aagcagttgt tttagctaca
     7921 tttacatcta tcgcaaacga agtgccagta acaaacggtt aaggagctga tttcttatga
     7981 ttcttgatcc taaaatggat ttagacgaaa tcaaaaacgc actaaagatt gataccgatg
     8041 atgacgatgt ggaagtaaga cgtgcggtgc aagctgcaat tgcatacatt agaggggcta
     8101 tcgggaatga taagccctct ttttataagc aagaaaatga cacggttgat ctgattaatt
     8161 tagctattct gcaattagca gatcattatt acaacgctcg atcagcaacc gtgagtggga
     8221 acttgcgaga gtacgattta ggttttacaa gcctaatctt gcaactcaaa gcaagatatt
     8281 tgctttttgt ggaggagtag cgtatgcccc ttattcaaac aggaaattta aatcaacgca
     8341 tcaagtttgt ccgagatacg acggtcaagg acgaggacgg gcaagttgtc cggacttcta
     8401 caaccattct tacttgctgg gcaagtgtgc agacacaacg cctgaacgat attaagacgt
     8461 ccattggtac ggctttggaa ggaacactga cgttcattat ccgctatcaa caaaaatcag
     8521 agctaaccaa tgatatgaaa gtgcgttgga atggaaaaac gtttgaaatc attacgatta
     8581 cgaaaggcga gtttgcgaag gacttcacga caatcattgc aaaagaggtt tcaaaatgag
     8641 tgtagaagtc gatgcaaccg aagtgtacaa agcgcttagg gaagtaaaag caaacgttca
     8701 acgagtggaa agcccagcac ttagaaaagc tggggagtac gctcaagaaa agttacaaca
     8761 aaacacacct tactgggatg gaacgaagtc aaacggtaaa cgtggttcgt atatgcaaga
     8821 acatgctaag gaccatgtgg ttacaagctc ggtaaaaaac ggattgatag aagtcggcta
     8881 tgataaagat gtttcttggc ggatgcactt tatcgagttc ggaacaatca aacaacgtcc
     8941 aaaaggtttc gtacaaaaaa cacaaaagca aatcgaaaaa caagtaacac aaatcattgc
     9001 tgacgaagta aaaaggaggc taggactttg aaaacggcag tatcacaagt ctattcaatt
     9061 ctgaatagca atgaaaaaac aaagaacatt gatttttaca ccaatagtgt tccggaatcg
     9121 gctcaaacag tacctagcct tccagttggc agaattacag agatattcgg caactatgaa
     9181 gatttcgcaa gcaacaatcc tttgaccatt caatttaacg tacaggtaga tgtatgggta
     9241 tcgaccttaa aagaggttga tgccttttat tttgcccttg atgagattat gagggggaat
     9301 ggttggcaat gcgcatacac ggaacaaaca gatgatgagg atttagaagg tgcaaagcgg
     9361 attatcaaac gatatgtagc aaatatttca ctaaattaaa aggagagaaa atagatggca
     9421 acagtaggat ttgagagcgt catttttggc gtaaaaacag gtgcaggcgg cactctaaaa
     9481 gaattagtag cagataagtc gaaaggcgga gcgatcgaag ctaaaattac tggattaggc
     9541 gcaacttcta acacaacata cgcttcaaac gtaccattct tcattgcaag taaaggggtt
     9601 tcgtcgccaa aagttacgct tgacgtggca gacttaatgg ataacggcat ttacagcgaa
     9661 atcattggcg ctaaaaccgt ggatggtgta aatgtaattg gttcagaaac tgaagcgcct
     9721 tacgtgtcgg tagtcatggt tacagcgaac aaagaaggaa aacgcttatt catgggattg
     9781 gcaaaaggaa aattcagtca tccagatatc gacatgaaaa cagctgaaga caaaggagtt
     9841 gaattgcaaa ccgattctat cgaaggggaa ttcatttctg atgaacgtgg ctatgtatac
     9901 ttaacagccg tagaatcaga agaaatgacc ttacaaaaat tcaaggactt ggtaaataac
     9961 aaagcggggg agtagttaac cctgcatcta caccaacgac agatacaggg acaccaaaag
    10021 aaccagaacc aaaaattgat acacaaggtt agccattttt tggctagcct tatttttttg
    10081 taaaaacaag gaggaaaaca aatgattgaa ttgcaattga aacttgacgg aaagaaaaaa
    10141 acattcaaac aacaagatat ttccgcacgt gcaatgcgtg agtgtatcaa attttacgag
    10201 aaagcggaaa aagcagacct aactgattta gaagcaattg attcaatgat tgcaattaca
    10261 gcagatattt tccaagatcc agcagttaca tttgatgcta ttttagacgg tttgactgcg
    10321 agcgagttag taccggcatt agaaagtgtt tttgaacaaa tcaatgaact gggaaacaat
    10381 gaaaaaaagc agacggcgag caaaaagaga taagtttttc tgaagctagg aaagcaatgg
    10441 atcaaatcta caaagattta atcgaatcag gttggacgat gagagatgtg gacgaagccg
    10501 actatcatta tttgttacac ctttttggag aagtggagag tggcgaagaa tatgtagatg
    10561 gtgctgattt catcaaacaa tttttatcgg ctgaagactt ggtaaaactt gaggaaggag
    10621 gtaaataatg gcaggaaaag gacaaccggc aggaaatatc aagctaggga ttagtttaga
    10681 tagcactaat tttggtaaca cgctggacga aatcaatgcg aaagtcaaac aagctgagtc
    10741 gaatatgcgt gccaatctaa aggcttatga ttcagcagga cgttcatacg aagcacttag
    10801 tcaaaagacg aaagacttgt ctacggttat ggaagggcaa aacgccaaag taagagaatt
    10861 aacaaagcgc cgtgatgaag cgattagcaa gtatggcgag gaatcgaaac aagttgctaa
    10921 ccttaacaca cagataaaca atgctaccgc aaaatataat gcttacagtc gccagttgaa
    10981 tgacacaaaa aaagaattgg tgtattccaa aacagccgtc aatgatttat ctaacgaaat
    11041 caaagaaaat gaacgacaaa tgaacgccga agtaaaagcg ttgaaagccg ctggtgatga
    11101 atctggtgcg tttgaagcaa aacaaaaagg gctagccaaa caaacggaat tatccgagaa
    11161 agctatcgaa gaacagcgca aagttgtgaa actgatggct gatgagtttg gcgattcagc
    11221 aaatgaaacc gaagatgcaa aaagggcatt agaaaagtta gaacgacaaa gccaaatatc
    11281 tagcaggcaa ttagaagcac tcaaaagctc cagcgatcaa tcaggaaaaa aaatagaaga
    11341 ttttggcgac aagtccacaa ggtcagctag gaaactggat gggctaaaag acaaattagg
    11401 ctcgctaaaa agcgcatttt cgtttggtgc agttgctgga ttagcgcata acgctattag
    11461 cagtgtagta agtggcgtgc aaggcttggt tggcgaagca gtaaacgcat cggattcatt
    11521 gatgaagttt tccaaaacca tggagtttgc taactttggg aagtcacaga tagaaagctc
    11581 gaaaaaagaa atgaaagact acgccgataa gacggtttat ggtttagaag aaattctgaa
    11641 cacaaccgca caattggcat ctaacgggat tcctaactat acagaactaa ccaaggcggc
    11701 aggtaacttg aatgccgttg caggcggttc tagtgataca ttcaaatccg ttgccatgat
    11761 gctaacgcag acggcaggag ctgggaaact aacaactgaa aactggaatc aattagcaga
    11821 tgcgataccg ggcgcttcag ggctgttaca agacgctatg ttgaaaaacg gagcttatac
    11881 aggaaacttc cgtgatgcaa tggcgcaagg tcaaatcact tctgatgagt ttaaccaagc
    11941 gattgtacag ttaggtatga atgacggagc agttaaagca gctacttcca cagatacatt
    12001 gagtggttct tgggaacaga tgaaatctac tgtaataaat gggttacaaa gtatcataga
    12061 caaagtaggc gttgaaaata tcactggttt catcaacaga gtaacaaaag ggattgaaaa
    12121 ttctattcct aaaattactc aatttatagg ttggttgaga gatattggaa cgtggatcgt
    12181 tgaaaataga gagccactaa catggattgt cggaatcata ggcggaatta cattagcagt
    12241 aaaagcattg aacgtagcaa gtatgttgct ggcaattact ggcggaacat tggcagcccc
    12301 ttttgtggcg attggtgtag cattaggcgc actagcaggt gctttggtga tagcttatac
    12361 aaaatctgaa acatttagaa atatagtcaa tgcggctttt acagctgtga aaaacgtagt
    12421 tatgagcgtt atcaataatt tggtggaata ctacaaaatg ttgtggagcg tgttgcagtg
    12481 gctttgggaa aaaataaaag aatgggcttc atggattggc aataaattca ttgaaatgaa
    12541 gaacagcgtt gtgaatacgg ttcagaacct atggaatggt gtgaaaaact tcttcagtaa
    12601 tggcgttgga gacacttgga ataaggtagt tggctgggta aaaaacattt tcaacaaagc
    12661 aactgaattg aagaacaaag tttctgatgc aattggtaac ctgtggaacg gtatcaaaga
    12721 cacattccgt agaggcattg atacggtatt caattggttt tcagaactac cgacgaagat
    12781 gaagaatgcc attattggcg gtaaaaatgc cattgttgat gcgttcaaaa gtattttcaa
    12841 cgcagcactt aaagcgatag gtaaaccagt taacgcaatc atccatggag cttcatgggt
    12901 actagaaaaa ctgggtgctg acaaactcga agaatggaaa gtgccacaat acgcaaaagg
    12961 aacaccaaac ggaggtcatc cgggcgggcc tatgatggta aatgacggta gaggtgctga
    13021 agcggtaatc acacctaacg gacaagcatt tatcccacga gggcgaaatg tagtgttgaa
    13081 tgcaccaaaa ggcacacacg ttctaacagc tgaagaaaca gcttatatga ctggaaacaa
    13141 agcaccaaga tatagatacg ccaaaggtac aggctttttc ggaaatctat ggaacaacgt
    13201 caaaggattt gctggagatg ttggaaacaa gctgaaagat gtagtcggcg atgtatggga
    13261 ttttgtaaca gacccgggag cgttggctag gaaagtgtta aatggtcttg gcgtactgga
    13321 agggcttgtc aaatatcctt tagatgttgg taaaggtatt ctaagcaagg ctaccgaagc
    13381 attgacgaac aaaatcacag aactattcag cagtggcagt ttagacactt caatgggcat
    13441 gcaaggcgtt tacaaatact tggcggacgt tgcagttgca gtaatgaaga agtttccagg
    13501 ctttgtggca actagtgggt atagaccagg tgacccctat tcgcatggta aacgtaatgc
    13561 cattgatatt gcactacctg gtgtcacagg aggctcgcca cgctacacag aagcagccaa
    13621 ttacgcattt gagaagtttg caaacaaaat cggctatgtt atcacaaatg gcaaggttcg
    13681 tgaccgttca ggacaatcag gtacaggtat tcacaatgat tggagaccat ggcccgatgg
    13741 agatcactat gatcatgtgc atttaaacgg tgtgaaagac ccacaaaaca ctcaaatttc
    13801 aggagatagc gtgggaggca gtggggtaga aagatggcgc aatgtagcaa ttagagcgtt
    13861 gaaaatgacc ggtcaataca gtactgcaaa cttaaatgca ttactaaatc aaatgcgtac
    13921 agagtcaaat ggtaatccta atgcagttaa caattgggat attaacgcca aaaatggaac
    13981 accatcaaaa gggttgctcc aagtgattga cccaacattc agacagtatg caatgccagg
    14041 attcaacagc aatatttttg acccactatc taacatctta gcttcaatca gatacgcact
    14101 atcaagatat ggctcactaa caaatgccta tcgtggagtt ggttacgcaa acggtggaat
    14161 tgtaaaccaa catcaaattg cggaaatcgc agaaggaaac aagccagaaa ttattattcc
    14221 tttagataag gctaaacgat caagagcgat gcaattattg tctatcgcaa tggacaaact
    14281 aggagtttct cctaaaactt atggaaatgc gacaactgtt tccagtgatt acgaaatcct
    14341 agaagccatt gaaaaacagg cggcaacaac gaatcagctg ttatcgttat tgctggcatt
    14401 tttcaaagga aatagccgaa ctgatagaga tttagcttta gatattcaga agatcttggt
    14461 taggaggatg tagatgcgaa ctgtattact gagaaataga ataaacgaag aaattgattt
    14521 gtctacggag gattattttg ctactgggtt gagtaatatg gggtttgaag taaaaaaaga
    14581 acatgtggga cagtggggga atttcagaga aagcagtgag aacgttgaaa tatctgaatt
    14641 tcagtcatct gtaatcattt ctgtgcatgg gtttcgagaa aaagaactgt acaattcact
    14701 tgtgcagttc ctatcggaag gtccgtttga actggaattt gcttttgacg gcgaaacaat
    14761 ggtaagaaga tgcagtctaa aatctttaag taagactgaa atcgatccga aaacatcgtt
    14821 actaacagac actttagaac tatatttcac atcaaactgg tattccgtaa aacgcgaaaa
    14881 attaattcag cgaccgaatg tagtgaaaac acgtggtaag gtttttccgt ataaaagatc
    14941 ttatatctac actcaaaact tgtgggagaa aaaaggtgta ttcaaattca ataataattc
    15001 tgtataccta acgaatagca aggaacggat gtccccgcta aaaattcgtg tgattgggaa
    15061 gtgttcaaat ccgtattggg aagtaatcca aaactcacaa atcatcgcaa cggatggata
    15121 cttcatagat atgactgaaa cacagactct agaagtatca agcctttttg aagatacaac
    15181 ggcgatttta aaagatattg caggggtaga atcttctgtc taccaacaac aggattatac
    15241 aaaaactaat tttgttcagg ccccgactgg agaattcagc attgtgtttc atgttggggg
    15301 ggcagacgta gagattgagt tatacgagga gcgtgatctg ttttgatttt agcagtcacg
    15361 ctttttcatc gtgatttaat gctttataac gaacatttat tctctaacag ttttgaattt
    15421 ggtgcggacg agatcaacga agaggctagt agctttacga tggataagta cgttcctgta
    15481 aaaacaggcg attttctact agcaaaatat attcctagtg gaaaatttgc atattttggt
    15541 gtaattacgt cgcaggaaga cgaaaaaatc agttgtaaaa gcttacttag tttagctgat
    15601 agtgagatac cgactgcacg tgtgtcagga gataactacg aagagcatat ccggcggttg
    15661 attgaatact atttgctgaa tgatccaacg aaacaactaa aagatatttt agacgtcaaa
    15721 gcagaaagtg cgacctctca ttcgtatcaa gctaccgata cgaataaaca caagttaagt
    15781 gcgtatattc tcaatggttt caaaaaatac aacgtaaaat ggtatttcaa gggaattcaa
    15841 aacagaaaaa tctatacagg catacgtgct gtaaatgaat caatttacat taaagacaat
    15901 tcttctgaat ttagcgattg ggatgtgttt gttcaggcgc cgggcgctgg aaacgagaac
    15961 aagctattaa tcgttgataa agcaatgaaa gatatagaga aaccgataat actgtcaaca
    16021 tggtatttgg acgaagaaaa caatttgaca caagatggat cgaaagaaaa tatcacgaaa
    16081 ccaactgtca atttggttaa tatctacgat caaaccgcag aagataaagc atcctacgaa
    16141 gatgtggcaa aatcagagtt gaaaggcaat acgtattcgc atgaaatcaa agtgaacgtt
    16201 gtaagaaatg caaaaaattt gaatgtcgaa acgattgaaa cagggatgtt tgccacgatt
    16261 tcttataaag gaaagatata caagtcggtt ttgacagctt ggcgaatatc aagtgataag
    16321 gagtttgtgg aattgacttt cggaaacata agaagtcgtt ttatggatta ttttgaagat
    16381 aatgggggat aaaaaatggt tagcaatgtg gatggatatc aatttgaaaa cgtgaaagta
    16441 agcgcagaaa atgatgctag actttatcac gttttatata atcggaaaaa tcaggttatt
    16501 gatggttacg atcagtctat gaatttatct tcaagcggat taacagtaaa agttgctgca
    16561 ggagcagcga ttattcaagg tcgtatggtc gttgttcgac aagaagaaag tataacagtt
    16621 ccagcaaact caagtggtta tatagcatta acagtggatt tgacacaaga agttatacct
    16681 ggatctattc ttccagaatc ggaagaatat gaatggacta ataatcaagt caagctagaa
    16741 tttataacaa aagttataaa aggtaattta aacaatggtg ataaggtcta taatttacca
    16801 ctatgctcag ttacttctac tggatcaact gtttcaatct caaagatatc ggatagttac
    16861 gagctgactc tctctaaagg agaaattttg tggagtggga ctgcgttaat gcatgatact
    16921 caaactgtcc aaccttcaaa aaaaatgtgg cagacagttt caggtttttt attagtatgg
    16981 ctcccatacg aaaacgggca agcaattggg gatagatatg taactacgcc tttttataaa
    17041 gagcgtgtaa cttttactaa tgttttagga gaaattgttt caggatttga tgactatcac
    17101 aaaaagtggt ttagtaaacg aataaactat aattcgaata ctaatatatt tacaggtgca
    17161 gcaagcaatg caagtggaga taacgcaaat atggtgctta ggtatatagt ttctttttag
    17221 ttaggaggta tggaagagtg gcaaatttag aaattaaatt atctgcaaat aagagacagc
    17281 cttatctacg tcaccgtgtt gttggtagag ttggtgatgg ggggctcaca acaatcaatg
    17341 tacaacttct tgaggaagat gaaattacac cttttgtaat taatctaaac ggtactttga
    17401 aatttgtggg cgaagtttca aacggtaact ataccgaggg agaaccagaa ataatcgatt
    17461 cgactaatgg gttaattagt tacacgttca ctaagtcaaa tttcagcacg agtcatcaat
    17521 tcaaacaagc atattttgaa tatgtagatc ctaacggcaa aaaagtaact tttcagaact
    17581 tcatcataga cgtgttagaa cgagtagata ttaattcgga gcaagcgaaa tactatattt
    17641 cttcattgga aaaattacag agtgaaatgc aaaccacttt caatcagttc attagtgata
    17701 aacaggtcca atacgatcaa atctactcga aatataacga attagtaaga ttgataaatg
    17761 aatcagataa gcaagtaaat gatcgtattg ataagacaaa tgatcgtatt gatcaaacca
    17821 atcagcaaat cggcgatctc ggcaagctga aaaagatgta cagtaacagc atcgacttcg
    17881 gggactatga ttatagtggg aatccgaacc ttagcgctaa acttaatgct tcaagttttt
    17941 ctttaggtac tggcgcaaca gtcgcggatg ataatgatga gattgtgttt accttagatg
    18001 gcacaaatca actatcgaag tacgctagca aagcgcaagt gccggtagca gaagggaaac
    18061 aatatacgat tagttgtgaa attatgttag aagatgggtt cactggcgac ccttcaggaa
    18121 tacgtctgca acacgcatat ttgccaggcg gggttgttgt tttacagaca gagacagtac
    18181 ctaaaaatga attgaatacg tggcagacgc ttatcggaac gcgaacggta aaatacacct
    18241 ctgacgtacc aaatgaatgg taccctttgt ttagagacat ccgaacactt aaaccgaccg
    18301 gtaaagttag actaagaaaa attaagat
//
LOCUS       DAFLWZ010000055        17748 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000055 DAFLWZ010000000
VERSION     DAFLWZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.055"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            30..842
                     /locus_tag="L1V38_001976"
     CDS             30..842
                     /locus_tag="L1V38_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBN1316523.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            839..1639
                     /locus_tag="L1V38_001977"
     CDS             839..1639
                     /locus_tag="L1V38_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBN1316524.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1800..3068
                     /gene="rseP"
                     /locus_tag="L1V38_001978"
     CDS             1800..3068
                     /gene="rseP"
                     /locus_tag="L1V38_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBN1316525.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3136..4845
                     /locus_tag="L1V38_001979"
     CDS             3136..4845
                     /locus_tag="L1V38_001979"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBN1316526.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5057..9415
                     /locus_tag="L1V38_001980"
     CDS             5057..9415
                     /locus_tag="L1V38_001980"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBN1316527.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9560..10033
                     /gene="rimP"
                     /locus_tag="L1V38_001981"
     CDS             9560..10033
                     /gene="rimP"
                     /locus_tag="L1V38_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBN1316528.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10056..11231
                     /gene="nusA"
                     /locus_tag="L1V38_001982"
     CDS             10056..11231
                     /gene="nusA"
                     /locus_tag="L1V38_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBN1316529.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11253..11546
                     /locus_tag="L1V38_001983"
     CDS             11253..11546
                     /locus_tag="L1V38_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBN1316530.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11543..11854
                     /locus_tag="L1V38_001984"
     CDS             11543..11854
                     /locus_tag="L1V38_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBN1316531.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11867..14173
                     /gene="infB"
                     /locus_tag="L1V38_001985"
     CDS             11867..14173
                     /gene="infB"
                     /locus_tag="L1V38_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBN1316532.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14200..14547
                     /gene="rbfA"
                     /locus_tag="L1V38_001986"
     CDS             14200..14547
                     /gene="rbfA"
                     /locus_tag="L1V38_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBN1316533.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14704..14877)
                     /locus_tag="L1V38_001987"
     CDS             complement(14704..14877)
                     /locus_tag="L1V38_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1316534.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15325..17687
                     /locus_tag="L1V38_001988"
                     /pseudo
     CDS             15325..17687
                     /locus_tag="L1V38_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
BASE COUNT         6053 a         3155 c         3903 g         4637 t
ORIGIN      
        1 ggaatctttt aagtatagga ggaaaaagaa tgttacgttt ttttccgcaa aaaaacaaat
       61 atattcaaga aaaaagcgaa tttcaattta ataccgatgg accaattcct cagcacattg
      121 ccatcatcat ggacggcaat ggtcgttggg cgcaaaaccg tcgtttgcca cgagttgctg
      181 gccataaaga aggcatggaa acagtaaaga aagtcacaaa aaaagcatca aggcttggag
      241 tgaaagtgtt gacgctttat gccttttcga ctgaaaactg gaagcgacca aaagatgaag
      301 taagttttct catgcaacta cctgtcgact tctttgatac gttcgtacca gaattgatta
      361 aagaaaatgt caaagttcat gtcatgggtt atgaaaacgt attgccagaa catacgcaag
      421 atgctgtaag acgtgcaatt gagcaaacaa aaaacaatac tggaatggta ttgaattttg
      481 ctttgaatta tggaagcaga gcagagatcg tgactgctgt ccaagaaatt gccgaagaag
      541 tagcaaaagg agaaatacac gcagaagaaa tcgatgatga attgattgct aagcatttaa
      601 tgacaggttt cttgcctaaa gagttacaag atcctgagct gatgatccgt acaagtggag
      661 aagagcgaat tagtaatttt ctgttatggc agatcgcata tagtgagctg tattttacaa
      721 aagcgctttg gcctgatttt gatggtgcgc atcttgaaga agcaatcgcc tcttatcaaa
      781 atcgagaccg tcgattcggc ggtgtaaaaa aaacagaaga tgagaaaggg gatcagtcat
      841 gaaacaacgt gtggtcacag cagccgtggc gctagtcttg tttattccga ttatatggat
      901 cggaggcata gcggttgagc ttacagcagc aatcttagca gtaataggag tttacgagct
      961 gtttcggatg aaaggattga cactcttaag ttttgaagga gttttatccg ccgttggtgc
     1021 agtgttactt gttttgccaa aagaaagatg gtttttcttt cttccagaga atgtaagtac
     1081 atttatgtta ttttatctta tagttatgat tcttttagga acatcagtta tttctaaaaa
     1141 tacgtatacg attgatgaag caggttttcc tgtgcttgtc agcttgtatg tgggaatagg
     1201 tttccagaat tttgtcaatg cacgaacaga aagcttggct gttttgatat ttggtctatt
     1261 tattgtttgg gcaactgata tcggagcata tatggttggt cgacgttatg gtcagcataa
     1321 gttaagtcct gatatttcgc ccaacaaaac gattgaaggt gcgctcggtg gtattggtag
     1381 tgctgttgta gtcgcatttc tttatttatt gctataccca gcaaaagaac tatttaatca
     1441 tggtatgttt gtcatgcttc tgatgacgat tattttttca gcagtcggac aatttggtga
     1501 tttggtcgaa tctgcaatca aacgtcatta tgatgtgaaa gactcgggaa atatcttacc
     1561 aggccatggt ggaatcttag accgtttcga cagtttgctg tttgtatttc ctatcatgca
     1621 tttatttggc attatttagt aagtatacct gcgtttcttt gtgaatttca taaaagacgc
     1681 aggtttttat ttttcattat attgatacta ttggtgtctt tggtatacta tggtaaaatt
     1741 atagtgtttt atcgttgttt tataaaaaac acaaaaaaca agtaaaggag aaaaaagcta
     1801 tgaaaacgat tctgacattt atcatcgttt ttggtatatt agtgattgtt catgagtttg
     1861 gtcatttctt ctttgcgaaa cgatcaggaa tcctcgttcg cgaatttgct atcggtatgg
     1921 gtccgaaaat ttatgggcat caagcaaaag acgggacaac atatacgctt cgcctattac
     1981 ctattggcgg ttatgttcga atggcaggca atggggatga tgaaacagaa atggcaccag
     2041 gaatgcctct ttctctttta ctaaattctg acggcatcgt agagaagata aatttaagta
     2101 agaaaatcca attgacaaat gctatcccga tggaattgag ccgttatgat ttagaagatg
     2161 agctgactat cactggttat gtgaatggag acgaaacaga agtagtaacc taccctgttg
     2221 atcacgatgc gacgattatt gaaaacgacg gaacagaaat cagaattgcg ccaaaagacg
     2281 tacagttcca atcggctaaa ttgtggcagc gtatgctgac caactttgct ggacccatga
     2341 ataactttat tttggcaatc ctgttattca tcattctggc atttatgcaa ggtggtgttc
     2401 aagtgacgaa cactaatcgc gtaggagaga tcatgcctaa tggagctgcg gcagaagcag
     2461 gcttaaaaga aaatgatgag gtagtcagtg tggacggaaa agaaatccat tcatggaatg
     2521 atctgacaac agtcattacg aaaaatccgg ataaaacatt agactttaag atcgaacgag
     2581 aaggtcaggt gcaatctgtc gacgtgacac cgaaatctgt agagtcaaat ggcgaaaaag
     2641 ttggccaact tggtataaaa gccccaatga atacaggttt tatggataag atcattggag
     2701 ggacgcgtca agctttcagc ggttcattgg aaattttcaa agccttagga tcactattta
     2761 caggtttcag tttagataaa ttaggcggac ctgtcatgat gtaccaattg tcttcagaag
     2821 cagcaaatca aggtgtaaca actgttatta gtttgatggc gcttctttca atgaatctcg
     2881 gaatcgtcaa tctgcttccg attcctgcct tagatggcgg gaaattagtc ttgaatattt
     2941 ttgaagggat tcgcgggaaa ccattaagtc aagaaaaaga aggaatattg acattagctg
     3001 gctttggatt tttaatgttg ttgatggtgc tagttacatg gaacgatatt caacgattct
     3061 ttttctagaa aaagttgaca aatagggtat aataacaaac gataactatt ttgaggaaat
     3121 aaaggagtat atagaatgag acaatcaaaa atgttgattc caacattacg cgaagttcca
     3181 aatgatgcag aagtattaag ccatcaaatc ttgctaagag ctggatatat ccgccaagta
     3241 tcagcgggta tttattcata tctgccatta gcaaatcgtg tattggaaaa actgaaacgc
     3301 attatgcggg aagaatttga aaaaatcgga gcggtagaaa tgctgatgcc tgccatcttg
     3361 ccagcagaac tttgggaaga atccgggcgt tacgaaacat atggaccaaa cttgtatcgt
     3421 ttcaaagacc gcaatgatcg aaaaatgatc cttggaccaa ctcacgaaga aacttttact
     3481 gatttgatgc gtaatgaaat caattcatat aagaaattac ctttaaatct ttatcaaatc
     3541 caacctaaat atcgtgacga aaaacgacct cgcttcggtt tgcttcgcgg aagagagttt
     3601 atcatgaaag atgcgtattc tttccatgca acggaagaaa gtttggacga gacatataaa
     3661 gattacgaaa aagcctacac cgaagtattc aagcgttgtg gcttagaatt tcgctcgatt
     3721 atcggagacg gtggcgcaat gggcgggaaa gactcaaaag aattcatggc gatctcagaa
     3781 atcggggagg atacgatctg ttattcgact gaaagtgatt atgctgcaaa cttggagatg
     3841 gctacaagct actatgtatc aaaaaaatcg catgaaacac agcttgaatt ggagaaagta
     3901 gctacaccta acgtaaaatc aattgacgaa gtagcagatt tcttttctgt tgaacctcaa
     3961 aaaatcatca agtctgtatt gttcattgcg gatgaacaac ctgtccttgt tttggtacgc
     4021 ggagaccatg aagtcaatga cgtaaaactg aaaaactttt tatctgctga ctttttagaa
     4081 gaagcaacag aagaagaagc acaaaaatat ctaggtgctg agtttggttc tgtcggacca
     4141 gtcggtgttt cagatgacgt aaaagtatat gcagaccgtt atgtccaaga tttagcgaat
     4201 gccattactg gagcgaacga aacaggattc cactataaaa atgtgaatcc agaacgcgat
     4261 ttcactgtac tttcttatga agatcttcgt tttgtacaag aaggagatcc ttcaccagac
     4321 aacaatggtg ttcttgcctt tactcgagga atcgaaatcg gacatatctt caaaatcggc
     4381 actcgttaca gtgaatctat gggagcaact gtactagacg aaaatggacg agaaaaattt
     4441 gtgattatgg gctgttatgg tatcggtgta agtcgtttat tatcagcaat cgtagaacaa
     4501 cattcagatg aacaaggaat caactggcca aaaggaattg cgccatttga tttgcatatc
     4561 gtccaaatga atctaaaaga cgaataccaa acaaacctga cgaatgaact agaagaagcg
     4621 atgacaaaag ctggctatga agtactggtt gatgacagaa atgaacgcgc aggagtgaaa
     4681 ttcgcggatt ctgatttgat tggctgtcca atcagaatca ctgtcggtaa aaaagcagtg
     4741 gatggaatcg tagaagtgaa aatcaagaaa actggcgaaa tggttgaagt acgtaaagaa
     4801 gaattggtga atactttacc aatcctcttg aaccaaggcg aataataagc gttaaaacac
     4861 agaaaataaa aatagctgaa tcagctgttt ttgacaatct gatgattcgc ttttaaaatt
     4921 ggaactgcga tttgaatcgc agttccaatt ttttaatgta aaactcagaa aaaacgagta
     4981 tactaaaagg tactgaaaaa gaagaggata agatgcgatc aattgcattg tttctcatca
     5041 gaaagggcgt atatctttgt cagaaaaacg agatttattt gaaaaactgt tggaacaaat
     5101 ccaactagag gaagcagaaa aaaatcatcc actgcttact gctggtgaaa tggatagtgt
     5161 agtggtccat cgtaaatcgc gtttatggga atttacgctg catttttcca aaattttgcc
     5221 tattatgcta tatcggtcat tgactcagca tctgactatc gcttttaaag atattgcaca
     5281 agtcaaactg aatatcttag cagatgacca gacattcgat gaacagctct tgcaagatta
     5341 ctgggcccaa gctttggaaa atcagcaatg cgatacacca ctagcacagc aagtattgaa
     5401 aacgcaggta cctgtgataa aagatcgtaa agtcatcttg ccaatcgaca gtacaggagc
     5461 tatttcttat ttgaagcaac aatacttgcc attagtagaa gagttgttcg tcagttacgg
     5521 attcccaaaa tttcgtatcg aaccagaagt ggatgagcag caagcggaac gagtattgaa
     5581 actttttgaa gaacgcaaac aagaacaggc agaagccttt atgaagcaag cagctgaaag
     5641 tctagttgtc cacgaacaaa agaaaaagga aagaaaagag caatcgccag ctcttgaagg
     5701 acccatccac atccagctag gacgaaatat tccagccgat gaaccaacga caccaatgat
     5761 cagtatcgtt gaagaagaac gaagagtcac acttgagggg tacgtattcg acaaagaagt
     5821 cagagaacta cgttcaaaac gcaagatctt gactttgaaa atcacagatt atacttcatc
     5881 atttatcgtc aaaaaattct cgaacggcga aaaagatgaa caagtatttg atgcgatcag
     5941 tgtcggtagc tggttaaagg tacgaggaag tattcaagaa gatacgtttg tccgtgattt
     6001 ggtcatgaat gcgcaagata tcatagaagt caaacataca cctcgcaaag attatgctcc
     6061 tgaaggggaa aaacgagtag agcttcatgt tcatagcaat atgagtacga tggatgcaac
     6121 aaacagcatc tctgatcttg tggcacaagc agggaaatgg ggacaccgag ctatcgccat
     6181 tacagaccac ggtggtgcgc aagcctttcc ggaagcacat agtgctggaa aaaaagcagg
     6241 tgtgaaaatc ttatacggcg tggaagcgaa tgtcgtagat gatggtgtcc caattgctta
     6301 taatgatgca catgaagcat tgagtgaagc cacatatgtc gtatttgacg tggaaacgac
     6361 aggattgtct gcagtatatg acacgatcat cgagctagcc gcagtcaaaa tgtataaagg
     6421 aaatgtgatc gaaagctttg atgaatttat cgatccagga catcctttgt cacgaacaac
     6481 ggtagatctg actggtatca cggatggaat ggttcgagga tcaaagtcgg aagaagaagt
     6541 attgcggatg ttccttgaat tttcaaaaga tacaattttg gtagcccaca acgcggcttt
     6601 tgatatgggg ttcttgaata ctagctacgc aaggtatggt attcctgaag cggccaatcc
     6661 agtcattgat acgttggaat tagctagata tctgtatcct caattcaaac gtttcggatt
     6721 aggtgtgtta tctaaaaaat ttggtgtcag cttggaacag catcaccgag caatctatga
     6781 tgctgaagca actggtcact tagcatggat ctttgtgaaa gaggcaatgg acaatcataa
     6841 catgctttat catgatcagc taaatgagca tatcggagaa ggagattctt acaaaagggc
     6901 tcgacctttc catgtaacga ttttagcaaa aaatcaggca ggactgaaag atttgttcaa
     6961 actgatttca atgtcgaatg tcgaatactt cgaacgcgtc ccacgaatac cacgctccca
     7021 attgaaaaag atgcgtgaaa atctattgat cggctcagct tgtgataagg gagaaatatt
     7081 cgaagccatg atgcaaaaag gggtagaaga ggcaagaaac cgagcaaaat tctacgatta
     7141 tattgaagtt atgccaaaag cggtctatgc gcctttgatc gagcaagaat tggtaaaaaa
     7201 tgaacatgat ttggaagaaa ttatccaaaa tttggtagaa atcggaaaaa gtttggataa
     7261 aatcgttgtt gcaacaggta atgtacatta tctgaacgaa gaagatgcca tttaccgaaa
     7321 aattttgatc aattctatgg gcggagcgaa tccgttgaat cgtcatagtt tgccggatgt
     7381 ccatttccga acaaccgatg agatgctaac tgcatttcac tttttagggg aagaaacagc
     7441 gaaagagatc gtagtagaaa atacgaataa aatcgcagat atctgcgaag aagtgattcc
     7501 agtcaaagat gaactttata caccgaagat tccaggttca gaagatgaaa tatcagaatt
     7561 gagttacaca aaagcaaaac aaatgtacgg agatccgtta cctgagatca ttcaaaaacg
     7621 attaaaaaaa gagttgaatt ctattaatgg taatggcttc tcggttattt atctgatcgc
     7681 ccaaaaacta gtgcataaaa gtaatgaaga tggctatcta gtaggttcac gtggctctgt
     7741 tggctctagc tttgttgcga cgatgacagg aatcactgaa gttaatccgt tagcccctca
     7801 ttattattgt ccagagtgcc aatattccga gttttttgaa gatggtacgt atggttctgg
     7861 atttgacatg ccagaaaaac aatgtccaaa atgtggtgca cgcttaaaca aagacggtca
     7921 tgatattcca tttgagacat ttttaggatt ccatggagac aaagtgcccg atattgattt
     7981 gaacttctca ggtgattatc aagcagaagc ccataactat acgaaagtat tgtttggcga
     8041 agactatgtt taccgtgccg gaacgattgg tacagtcgcc gacaaaacag catatggcta
     8101 tgtaaaagga tacgaaaggg acaataatct gcagtttcga agtgcagaag tcgacagatt
     8161 agcaaaaggc gctactggag tcaaacggac aaccggccag catccagggg ggatcatcgt
     8221 tattcccgat tatatggatg tctatgattt tacgccgatc caatatccag cagacgatca
     8281 aaattcggaa tggaaaacga ctcattttga ttttcactcg attcacgata atgtattgaa
     8341 attagatatt ctagggcatg atgacccaac tgttattcgg atgcttcaag atttatcagg
     8401 gatcgatcca caaacgatcc ctacggatga cccggaagtg atgcggatat ttgccggtcc
     8461 tgaagtactt ggagtaagtc aggaacaaat ttattccaaa acagggacat taggtattcc
     8521 agaattcggc actcgttttg ttcgagggat gctagaagaa acgcatccta caacttttgc
     8581 agaactactg caaatttccg gactatctca tggtacagac gtatggttag gaaatgcgga
     8641 agaattgatt cgacgaggag atgcgacact ggcggaagta atcggctgtc gtgatgatat
     8701 tatggtttat ttgatccatg ctggattaga tagcgggatg gcatttaaaa tcatggaaac
     8761 tgttcgtaaa ggacaatgga acaagatccc tgatgaattg cgagaaacct atctatcggc
     8821 gatgaaagaa aataatgtgc ccgactggta tatcgattct tgttcaaaaa tcaaatatat
     8881 gtttccgaaa gcccatgctg cagcttacgt attgatggct cttcgtgtcg cttatttcaa
     8941 ggtttatttc cctattttgt attactgtgc atacttttct gtacgtgcag acgactttga
     9001 tctagtctcc atgtgcaaag gaaaagatgc tgtgaaacaa gcaatgaaag aaatcacgga
     9061 caaaggatta gatgcttccg taaaagaaaa gaatcaactg acagtgctgg agttagccaa
     9121 tgaaatgctg gaacgaggat tcaaatttgg aatgattgat ttgtataaat cggatgccgt
     9181 taactttgtt attgaaggtg atacgttgat cgcaccattt agagctgtcc caagtttggg
     9241 aaccaacgtg gcaaaacaaa tcgttgaagc aagaaaagac ggtccatttt tatccaaaga
     9301 agatcttgcc acccgcggta aagtttcaaa aacattgatc gaatatatga acgacaatgg
     9361 cgtattgaaa gatctaccag atgaaaatca attatcgtta ttcgatatgc tataagcatc
     9421 tgttttcctg tctgcttgta attttaagca gagtatggta tagttcttat aggtaatgat
     9481 actaactgtg agtgagcgga tttttcgctc actcttttta atggaattac gcacttaatt
     9541 ttttaaggag gcgaaacttt tgagtagcgt cgttgaaaca gtcacagaaa tggtgacacc
     9601 gattttagat gaacaaaatt ttgaacttgt cgaagtcgaa tttgtaaaag aaggaaaaag
     9661 ctggttctta cgagtattta ttgacaaaga aggcggtatc gatatcgaag aatgcgcctt
     9721 tgtcagtgag aaactgagtg aaaaacttga tgcagcagat ccagatccga ttcctcaagc
     9781 ttatttcctg gaggtatcct ccccgggagc agagcggcca ttgaaaaaag aaagcgacta
     9841 tgaaaaggca cttggtgatt atgtccatgt ctccttatac caaccagtag atggcgaaaa
     9901 acaatatgaa ggatttcttc aatcatttga tgctgaacag cttacattga aaatacgcat
     9961 aaaaacacga gaaaaagaat tgacttttga ccgaaaaaat attgcaaaag ctcgcttagc
    10021 tatccaattt taatcacgga gaggaatcag aaaaaatgag taaagaaatg ttaaatgcgt
    10081 tagacgcttt agaagctgaa aaagggatct caaaagaaat cgtgatcgat gctttagaag
    10141 cagcattggt ttctgcatac aaacgtcact atggccaagc acaaaacgtc gaagtggaat
    10201 ttgatcagaa aaaaggaaag atccatgtct atgcggtaaa agaagtaacg gaagaagtga
    10261 tggattcaca gttggaagtc tcattgaaag atgcactttt aatcaatcca gcatatgaga
    10321 tcggtgatac gatccgtttt gaagtaacac caaaagattt tgggcggatc gctgcgcaaa
    10381 cggctaaaca agttatttta cagcgtgtac gtgaagcaga aagaacgatt atttataacg
    10441 aattcagtgc ttatgaaaaa gacatcatgc aaggaatcgt cgaacgccag gataaacgtt
    10501 atatttatgt caatcttggt aaaattgagg cagttctttc taaacaagat caaatgccaa
    10561 atgaatttta tcaaccacat gatcgaatca aagtttatgt ttcccgagta gaaaatacgt
    10621 ctaaaggtcc gcaagtattt gttagccgca gccatccaga cctattgcgc cgcttatttg
    10681 agcaagaagt accagaagtc tatgatggaa tcgttgaaat tgtcagcatc gcccgtgaag
    10741 ctggcgatcg ttcaaaagtg gcagttcgct caaatgatcc aaatatcgat gcagtcggta
    10801 catgtgtcgg gccaaaggga caacgagttc aagcaatcgt caatgaatta aaaggcgaaa
    10861 acatggatat cgtcgaatgg aatgaagatc cagctgtatt cattgcaaat gcattgaatc
    10921 ctgcacaagt catggatgtg atcttcgatg agacaaatcc aaaggcctgc acagttgtcg
    10981 ttccagacta ccaattatcg ctagcaatcg gtaaacgcgg acaaaacgca cgtttagctg
    11041 ctaaattgac taaccataaa atcgatatca aatcagaatc tgacatgacg gaattttatg
    11101 aaaatcaaga acaacaaaaa gaaacagaag aactgcatga tgaagcaatc gttcagtcag
    11161 atttaacaga cgatgaatat gaaacaattg cattcaacaa tgaaacggtc gaagaaaaac
    11221 cagaagctta actttagtaa ggaggcaaag agatgaaaca aaggaaaatt cctttacgca
    11281 aatccgtggt ttcaggtgaa atgaaaccta aaaaagagat ggtccgaatc acccgttcaa
    11341 aagaagggga agtatcgatc gatccaactg gaaaaatgcc tggacgagga gcgtatgtct
    11401 cacttgagcc ggaagaagta caacaagctt gggataaaaa aattctcgat cgagtactcg
    11461 aaacaacatt aacagatgag ttttatcaag aacttcttga ctatgtcact caccaaaaag
    11521 cacgtaaaga gttatttgga aaatgaatac agttaatcgg caaaaagcca tgaatctcat
    11581 cggtctagcg atgcgcgcgg gaaaactaat cacgggtgaa gaactgacca ttgctgaaat
    11641 ccgcaaacaa aaagcaaaat tggtgtttgt ggcaaccgat gcaagcgaga atacaagaaa
    11701 aaagataaaa gataagagtt catattatga agttccttgc tttgagctat tttctgaagc
    11761 agaaatcacg cagatgatcg gaaaacctcg caaggtattc ggaataatgg atgccggatt
    11821 tgcgaagaag accaaggagc taattgaagg ttaggaaggt gattgcatgg gcaacaaaag
    11881 aatctatgaa ttagcaaaag aactcaaaaa atctagtaaa gacgtcgtgg aaaaagcaca
    11941 acaacttggc atcgatgtga aaaaccatat gggtgcgatt actagcaatg atgagaagaa
    12001 attgcaacaa gcgttcaaaa acccaagcac gaaacaacaa gctgcacaac aagcaagcag
    12061 aaaaccagcc aatcaacagc cgaacgatca acgtaaaaaa gaaacaacga acaatcaaca
    12121 aaaaaataaa aataaccgca gttatcaaga tcgcggtcaa gggagcggtc aagtgaatca
    12181 aggaaaaaaa ccaacaacaa accaaaataa tacgggaaat accagcagcc aaaatcgtca
    12241 aggaacgagc caaggcggca atcaaaaccg tactaacaat aacaacaaac caaacaataa
    12301 caatcgcggc aaatttaata ataataaccg taatcgttat aataaaaaag gtaaaaaagg
    12361 caaacagcaa caatcaacta aaccagctgt accaccacgc aaattccgtg aattgccaga
    12421 tgtattagag tatactgaag gtatgaacgt agcagatatt gcgaaaaaaa ttcatcgtga
    12481 gccagcagaa atcattaaaa aattatttat gcttggtgtc atggtcaatc aaaaccaagc
    12541 actggataaa gatacgattg aactgttagc gacggactat ggcatggaac cacaagaaaa
    12601 agtccaagtt gacattgctg atatcgataa attcttcgag gcagaagaag tcgatccaga
    12661 taaattagtc tcacgtccgc cagtcgtaac gattatggga cacgtagacc atgggaaaac
    12721 aactttattg gatacattac gccattcacg tgtaacaagc ggcgaagccg gcggaatcac
    12781 acagcatatc ggtgcctacc agatcgatat tgatggtaaa ccaatcactt tcttggatac
    12841 accaggacat gcggccttta caagtatgcg tgcacgtgga gcaagtatca cagatatcac
    12901 gatcttagtt gttgctgcag atgatggcgt catgccacaa acagttgaag caatcaacca
    12961 tgccaaagct gcaggcgttc caatcatcgt cgctgtaaat aaaattgata aaccaggtgc
    13021 aaaccctcaa catgttatgc aagaattaag tgagtatgag ttaattcctg aagcatgggg
    13081 tggagaaacg atctttgttg agatctcagc gaaattcggc caaaacatcg aagaattgct
    13141 ggaaatgatc ctgttagtcg cagaagtaga agatttaaaa gcagatccaa cacaacgcgc
    13201 aatcggaaca gtgatcgaag cacgtcttga taaaggtaaa ggtcctgtgt caaccttact
    13261 tgtccaagaa ggaacacttc atgttggtga cccaatcgtt gtcggtaata cttacggacg
    13321 tgtccgtgta atgacaaacg atcttggccg tcgcgataaa gaagcaggac ctgcaacgcc
    13381 agtagaaatc actggcttga atgatgtacc tcaagcaggt gaccgtttcg tagtcttcga
    13441 agacgaaaag acagcacgtg cagcgggtga agaacgcgcg aaacgtgcat tattagaaaa
    13501 ccgtgctgcc acaagccgtg tgactttgga taacttattt gaaagcctga aagaaggcga
    13561 attgaaagaa gttaacgtaa tcatcaaagc agatgtacaa ggttcagcag aagcactggc
    13621 tgcatcattg aagaagattg atgtggaagg tgtccgtgta aaaatcgtcc attcagctgt
    13681 cggagcaatc aatgaaagtg atgtaacctt agcagcagcc agcaacgcta ttatcatcgg
    13741 tttcaacgtt cgtcctacac cgcaggcaaa agtgcaagct gatactgaag aagtcgatat
    13801 tcgtcttcac cgtatcatct ataaagccat cgaagaaatc gaaactgcga tgaaagggat
    13861 gctagaccct gaatttgaag aaaaaatcac cggtcaaatg atcgttcgtg aaaccttcaa
    13921 agtttctaaa gttggtacga ttgcaggtgc ctatgtaaca gaaggatata ttcgtagaga
    13981 tagcggtgtc cgtgtaatcc gtgacggaat cgtaatctat gaaggccaac ttgcaagtct
    14041 gaaacgattc aaagatgacg tgaaagaagt caaaatgggt tatgaatgtg gtgcaatgat
    14101 tgaaaaattc aatgacatca aagtagatga cgtaattgaa ggatttatca tggaagaagt
    14161 caaaaatgac taaaaactga taaaaggagg ccaatcatta tggctaacta ccgtgaccgc
    14221 cgagtcggtc aagaaatctt aaaagaagtc aatgatattt tgcgcaaaaa ggtccgtgac
    14281 cctcgtgtgg agaacgtaac gatcacagat gtgaaagtta cgggggactt acagcaagca
    14341 acgatctatt acagcatttt atctgactta gcatcagata agaaaacagc acaagatgga
    14401 ttgaataaag catcaggatt gattcgtcga gagttagggc acaatctaag tatttataag
    14461 acacctgaat tgttctttga acttgatgaa tcagttgtct atggcaacca tatcgatgaa
    14521 ttgcttcgcg acttgaacaa agactaatca aaaactcccg caaatcctgt gaaatcaggg
    14581 gttgcgggat ttttttgttt tcattaagac gtattaccta agagttccat gactttagtc
    14641 ttgcggcgtg tcagctaacc aaaaaagaga aaaagaaaag taaaaaattc gactttcttt
    14701 tttctagtag tatataaatt tttgcatata gataaagatc aagataccga taacggaagc
    14761 tagattgtaa tctattttag tgacagtcag gtatagccaa gtaactagaa gatcagtgga
    14821 acctgcacca taaaagtttg agtttgtcgg tccgttgaca gttaaaagaa aaatcacgtt
    14881 gaagttattg atatttccga ttacgccgct tcgatttggt cacgatccaa attttggata
    14941 atccctgtag aaattagcat agtagctggg ataccaattc acatattgac aaagataaca
    15001 gagactttta cataaaacgg atcaatcagg aaaggaattg ctcgatccag ccccagtttt
    15061 ccagcaatgt gttaactggc ccagcgtcat tcagcaaatt atgcatgatg aggagcgaaa
    15121 tgaactgcgg aacagccatt gtgataacga caagtttttt ggatcaatgt aaaaaacgtc
    15181 agcgaaagga aaaatttcgt ggttttttat acctgttcat ttggctagat ataaaatcca
    15241 aacaaatgaa cagaagtgct tattaggttt caattgggag tatctgcgct agaataagag
    15301 taataatgaa aaggagtgtt atgtatggat tattctagta aagaatactt tgataaaatg
    15361 acggcttggt ggcgtgctgc taattatctt tctgttgggc aactttatct taaagataac
    15421 cccttactga gacgtacact gaaacccgaa gatgtcaaaa aacatccaat cggtcattgg
    15481 ggaacgattc ctggccaaaa ttttatttat gtccatttga accgagtcat caataaatat
    15541 gatttgaaca tgttttatat tgaagggcca ggacacggcg gacaagtcat ggtatcgaat
    15601 gcttatttag atggaagtta cacagagatc tatccagaag taacggaaga tgagacagga
    15661 atgcaaaaat tattcaaacg attttcattt cctggaggca ttgcttctca tgcagcacca
    15721 gaaacaccag gttctatcca tgaaggcgga gagcttggat actctctttc acatgcagtc
    15781 ggagctgtat tagacaatcc tgaagtaatc tctgctgtcg tgattggtga tggtgaagca
    15841 gaaaccggtc ctttagctgg aagctggttc tcaaatgtct ttatcaatcc agtgatagat
    15901 ggagctgttt taccgatcct tcatttaaat ggtgcaaaaa tagccaaccc aacgatcttg
    15961 gcacgtaaat cagatggaga attagcaaat tactttaacg gacttggctg ggaacctttc
    16021 tttattgaag gaaatgattc agaaaaatta aatcctgtta tggctgaaaa aatggatcaa
    16081 gcaatcgaga aaattaaatc catccaaaaa gaagctcgcc tgaagacagc aacagatgtc
    16141 gtgatgccaa aatggccagt attgatcgta cgcacaccaa aaggatggac cggtccaaaa
    16201 gaatgggacg gggaaccaat tgaaggaacc ttccgagcac accaagtacc gattcctgta
    16261 gatcaagaac atatggatca tgcagatgct ttactccgtt ggctgaaatc ctatgaacca
    16321 gaaaaattat ttgatgcaca aggacgtatt ttagaagaaa tcagagaaat cgcgcctact
    16381 ggtgaccaaa gaatggcaaa aaatcctatc accaatggtg gaatcgatcc aagaccgctt
    16441 attatgccag attggaaaaa atatactttg caatttgaaa aaccaggctc cgttaaagca
    16501 gaagatatga ccgaacttgg taaattcgtt cgcgagatca ttgagaaaaa tccagaaaat
    16561 ttccgtatat ttggaccaga tgaaacaaaa tcaaaccgat tgaatcaagt tttcaaaacg
    16621 acaaatcgcc aatggatgga aaaaatcgaa ccagaaaatg atgaatggct ttcgccatct
    16681 ggtcgcgtca tcgacagtca attatcggaa caccaagatg aagggttctt agaagggtac
    16741 gttctgactg gacggcatgg ttttttgcaa gttacgaatc attcttgcga gtggttgact
    16801 ctatgttgac tcagcacttc aaatggatgc ggaaatcaca tgacctttct tggcgaaatg
    16861 attatccttc gctaaatctc attgcaagct caacagtctt ccagcaagat cacaatggat
    16921 atagccacca agatccagga atattgacac atttggcaga aaagaaggcg gagttcatcc
    16981 gtgaatatct gcctgcggat gcaaatacat tgctcgcagt catggataaa gcattccgct
    17041 cgtcagaaaa aatcaatttg atcatctctt ccaaacatcc gcgtgctcaa ttttactcag
    17101 cagaagaagc agccgtctta gtgaatgaag gcttgaaaat cattgattgg gcttcgacag
    17161 caaaagagga ggaacctgaa ttggtcattg ctgctgcagg aacggaatct aacttagaag
    17221 cattagcagc tgtaactttg ctgctggaag aattcccaaa actaaaaatt cggttcatca
    17281 atgtcgtaga tttattgaaa ttacgtcatc caagtcaaga tccgcgtggg ttgagcgatg
    17341 aagaatttga tcaatatttt acaaaagaca aaccgatctt atttgctttc cacggttatg
    17401 aaacattggt ccgcacgatt ttctttgatc gtcataacca tcatttaatg attcatggct
    17461 acaaagaaaa tggagatatc acgacaccat ttgacatgcg tgtagtaaat gaacttgatc
    17521 gttatcattt ggcaaaagac gcagctttaa aaatcaaagg aagtcaagca gaagattttg
    17581 cgaaaaaaat ggatcagaaa ttacaagaac atcaaaacta tattcgtgaa aatggtattg
    17641 atctgccaga agtattggat tggaaatgga aaaatcttga ccaataaaat gataaaatcg
    17701 atcccgcaaa atagaatttt ttacattgat taagaaactg aaaaaata
//
LOCUS       DAFLWZ010000056        17608 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000056 DAFLWZ010000000
VERSION     DAFLWZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.056"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="L1V38_001989"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="L1V38_001989"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBN1316535.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="L1V38_001990"
     CDS             complement(2261..2512)
                     /locus_tag="L1V38_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBN1316536.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="L1V38_001991"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="L1V38_001991"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBN1316537.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="L1V38_001992"
     CDS             3462..3680
                     /locus_tag="L1V38_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316538.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="L1V38_001993"
     CDS             complement(3969..4481)
                     /locus_tag="L1V38_001993"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBN1316539.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="L1V38_001994"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="L1V38_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBN1316540.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="L1V38_001995"
     CDS             complement(6934..7377)
                     /locus_tag="L1V38_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBN1316541.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="L1V38_001996"
     CDS             complement(7378..8166)
                     /locus_tag="L1V38_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1316542.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="L1V38_001997"
     CDS             complement(8163..9104)
                     /locus_tag="L1V38_001997"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBN1316543.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="L1V38_001998"
     CDS             complement(9281..9868)
                     /locus_tag="L1V38_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBN1316544.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="L1V38_001999"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="L1V38_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBN1316545.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="L1V38_002000"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="L1V38_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1316546.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="L1V38_002001"
     CDS             complement(12785..13720)
                     /locus_tag="L1V38_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1316547.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13906..14865
                     /locus_tag="L1V38_002002"
     CDS             13906..14865
                     /locus_tag="L1V38_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBN1316548.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14951..16045)
                     /locus_tag="L1V38_002003"
     CDS             complement(14951..16045)
                     /locus_tag="L1V38_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1316549.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16234..16995
                     /locus_tag="L1V38_002004"
     CDS             16234..16995
                     /locus_tag="L1V38_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1316550.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17110..17550)
                     /gene="fabZ"
                     /locus_tag="L1V38_002005"
     CDS             complement(17110..17550)
                     /gene="fabZ"
                     /locus_tag="L1V38_002005"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1316551.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5059 a         3835 c         3087 g         5627 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13861 caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac ctacaaacat
    13921 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
    13981 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
    14041 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
    14101 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
    14161 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa ggtctgtttc atgcggtatg
    14221 agaacacttt atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa
    14281 ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca
    14341 atccatgatc gacctgataa ttatcctgat ttcaattctg agtttggtca ccttgaaggt
    14401 gatacgatcg ttggcattca tcataaaagt gccgtcatta ctttagttga aagattatct
    14461 aaagtcatta tcacgattaa acccaacggc cgtaaggcat tagatattga aactgccctt
    14521 aatcaatggt tttctcgctt ccctaaaaac ttctttaaat ctattacgtt tgactgtgga
    14581 aaagaatttt ctaactggaa agccattagt aaccaacatg atattgatat atattttgcg
    14641 gaccctggaa caccttctca acgcccatta aacgagaatt ctaacgggat tctgcgtcgt
    14701 aatggactgc cgaaatcaat ggattttaga aaagtgaatc agacatttat ttccagtgtc
    14761 agcaatcaac gtaatcatat tccaagaaaa tcattgaatt acagaacacc aatcgaaata
    14821 tttttgagct atgtacaaga agcattttat tctagcttaa tttgacaaat cataacctat
    14881 aaaaaaacaa aataaaaaag cagaaataac tggctatttc tagcggatta tttctgcaat
    14941 aactaattat ctatttttta ttttcaatta atttaaagct tgaccatggt ttcaaaaagt
    15001 caaggaggaa taattcgtca tcggagattc ttcctacaac attgacacgt ccgtcgtttt
    15061 tcatatcctt caaggcgatt tgtgtttctc ctttgtattg accgtaccct tcattgtcaa
    15121 tcagtacatc cccatgatgc atatctcgcg tattatgagg cgggaaatct ttatctttgt
    15181 agtatacacg agtcatcgtt gaacgaagga tatattctga gcgatcccct cgataactat
    15241 gaaggttatc aaacaagcag attcgttcgt tttctgtaat accttcttcc gtatctactt
    15301 tcaatgttgg ataatccgcg ttaaatgctt ctgccatttc tttcaattct tcttcacttg
    15361 cgtacgcatt tccaatagaa atatcatcaa tcaatcctgt aaggattaaa tgcttcactt
    15421 gtgtcgcaat ttcaagatct cggtggtctt ccagcgtgca caagccatct tgcgtaggcc
    15481 aagggccaaa ctcagcagat tgcgaattga cgaatgccat cgtattcaaa ttatattttc
    15541 tgaatttttc tgaacaaaaa acaaagtgtt cgtatcctaa accagagtat cgatgaggat
    15601 aaaaattatg agaacctaat aaattatccg tgtttggcga ataactcatg atgttgtcaa
    15661 cgtaattcgt gcccgaactc atattgatct cgattttgat accaaaagga ttgcgcgtca
    15721 tttttgcttc ttctgctcct gtgaatccga tatctaagcg gaccccgtag gcacccatct
    15781 tatggaaaaa agataagtca tcgtaagaaa tctccaactg ttcaaataac gctggattga
    15841 tatcaaccat tacttccatg cctaggctat tcgcgtaatc aactacttct ttaaattctg
    15901 aaagaacttt ttctttatca tcattgatct gcagcaaact ggtaaaaacc cgtttatacc
    15961 catacttatg agctaaatcc aagtacgctt tgtccttttc aaatgttgac cgttctggat
    16021 aaatcgagat tcctaatttt cccatattac catttcctcc tgcatctttt cgtttttgta
    16081 tccacttaca ttatagcaaa cacaaagtaa atggtctaca ccttttcttt ttcttttaaa
    16141 ataaatgata aattccaata atttaagtag gtattttccc tctattttgt tatcattaaa
    16201 gataacaaaa tagtaaattg gaaaggaaca gttatgaaga aaaataaagt tattttaagt
    16261 attagtttag cagcagcatt gctgtttgct gctggttgtt ctgcaaacaa cacgacttct
    16321 tctagttcgt ctacagaaag ttcaaaaagt acatctactg cggaaagcac gactgccagt
    16381 agcgtcgatt tgaacgcatt ggaattacca caattgacga aagatgtcgc cgaaaatgaa
    16441 gatctggtcg aaatggtgac gaataaaggc acaatcaaaa tcaaattatt tcccgaacac
    16501 gcaccaaaag cggttgaaaa ctttatgaca catgcaaaag acggttacta caacggactg
    16561 actttccatc gcgtcatcaa agatttcatg atccaaggtg gcgatcctaa aggcgatggc
    16621 actggagggg aaagcatttg gggagaagga tttgaaacag agatcaacaa ccacctttat
    16681 aatataagag gtgcgttatc tatggctcgc tcacaagatc ctaacagtaa cggcagccag
    16741 ttctttatcg ttcaaaatac agatgatatg catgatggtc ttttaaaaga cgactatcct
    16801 caagcaatca tcgacgctta taaaaacggc ggttatcctt cactagatgg ccattatact
    16861 gtcttcggcc aagtgattga aggaatggat gtcgtggatg ctattgcaaa tatcgaaaca
    16921 gatagttcag acaaaccaaa agaagaagta aaaatcgata aaatcaatat actgcaagaa
    16981 gcaaaacaaa aataaaaaaa taacgtctga atcctgcata gatgacaacg tatgctagga
    17041 ttcaggcgtc ttctttttac ataaaaagca agtaagcttc cttttgtttt gctatatcag
    17101 gttttatagt caagcatttt ggttgacgat gaacgtgaac tcgcactcac agactttttt
    17161 atcatctaca tatgctgcag ataacgctgt accgactgat cccttcattt tggtgatttc
    17221 aaaatgacat ttcagcacat ctcctggaac aactttttga cggaatttgg ccttattgat
    17281 cccaccgata taagctcttt ttcctagaaa ctcttctgat tttaggataa gtatcgaacc
    17341 tgcttgtgcc agtgtttcta gaatcaacgc acccggcatc actggattgt caggaaagtg
    17401 accttggaaa aaatcttcat tgattgttac attttttgtc gcaacgatct tttttcctgg
    17461 ttctaaagta tctacataat caatataaca aataggataa cgattaggaa tcaattccat
    17521 tacttcagta gcagataata cgtaagacat aattaaactc cttctttcag gcaattgcca
    17581 ttttcattac tttgactatc aaagtatc
//
LOCUS       DAFLWZ010000057        17153 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000057 DAFLWZ010000000
VERSION     DAFLWZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.057"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(67..1047)
                     /locus_tag="L1V38_002006"
     CDS             complement(67..1047)
                     /locus_tag="L1V38_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1316552.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(1071..2555)
                     /gene="galT"
                     /locus_tag="L1V38_002007"
     CDS             complement(1071..2555)
                     /gene="galT"
                     /locus_tag="L1V38_002007"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBN1316553.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(2567..3556)
                     /gene="galE"
                     /locus_tag="L1V38_002008"
     CDS             complement(2567..3556)
                     /gene="galE"
                     /locus_tag="L1V38_002008"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBN1316554.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            3804..3971
                     /locus_tag="L1V38_002009"
     CDS             3804..3971
                     /locus_tag="L1V38_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBN1316555.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(4033..5844)
                     /locus_tag="L1V38_002010"
     CDS             complement(4033..5844)
                     /locus_tag="L1V38_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBN1316556.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(5841..6206)
                     /locus_tag="L1V38_002011"
     CDS             complement(5841..6206)
                     /locus_tag="L1V38_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBN1316557.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(6369..6764)
                     /locus_tag="L1V38_002012"
     CDS             complement(6369..6764)
                     /locus_tag="L1V38_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1316558.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(6782..7744)
                     /locus_tag="L1V38_002013"
     CDS             complement(6782..7744)
                     /locus_tag="L1V38_002013"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBN1316559.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(7744..7956)
                     /locus_tag="L1V38_002014"
     CDS             complement(7744..7956)
                     /locus_tag="L1V38_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBN1316560.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(7977..8675)
                     /locus_tag="L1V38_002015"
     CDS             complement(7977..8675)
                     /locus_tag="L1V38_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1316561.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(8695..9237)
                     /locus_tag="L1V38_002016"
     CDS             complement(8695..9237)
                     /locus_tag="L1V38_002016"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBN1316562.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(9369..10373)
                     /locus_tag="L1V38_002017"
     CDS             complement(9369..10373)
                     /locus_tag="L1V38_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1316563.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(10370..11359)
                     /locus_tag="L1V38_002018"
     CDS             complement(10370..11359)
                     /locus_tag="L1V38_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1316564.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(11356..12162)
                     /locus_tag="L1V38_002019"
     CDS             complement(11356..12162)
                     /locus_tag="L1V38_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316565.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            12328..13284
                     /locus_tag="L1V38_002020"
     CDS             12328..13284
                     /locus_tag="L1V38_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1316566.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(13361..13879)
                     /locus_tag="L1V38_002021"
     CDS             complement(13361..13879)
                     /locus_tag="L1V38_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1316567.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(13967..14116)
                     /gene="rpmG"
                     /locus_tag="L1V38_002022"
     CDS             complement(13967..14116)
                     /gene="rpmG"
                     /locus_tag="L1V38_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1316568.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            14344..14790
                     /locus_tag="L1V38_002023"
     CDS             14344..14790
                     /locus_tag="L1V38_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1316569.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(14985..16880)
                     /gene="asnB"
                     /locus_tag="L1V38_002024"
     CDS             complement(14985..16880)
                     /gene="asnB"
                     /locus_tag="L1V38_002024"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBN1316570.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         5164 a         3649 c         2962 g         5378 t
ORIGIN      
        1 tttgcccctt cctgaaacac aaaaaagctg cggtatcact ccattttccc acagcttttc
       61 catcttttat ttcgttgatt ctcgaataat caactctgtt tccacaataa tctttcttga
      121 aaccggtgct ttggaattac ttaattgaag aatcgtctcc actgctagct ctcccatcca
      181 ttcggtataa acttttacag tagaaagcga gggcgttaca tatttcgcta cactgacatc
      241 attgaagccc atcacagaaa tatcttctgg taccactaaa cctttttctt gaatcgcttt
      301 cagtgcgcca atcgctaatg catcattagc tgcaaaaagc gcatcaggaa catgcggatt
      361 cgtttttaaa tattgcttca ctgcttgata tcctgactcg acagaaaaat ctgcttcgat
      421 aattggacct tcgtcgtagc ctttttctgc caaaacttgt tgaaatgcca taattctggg
      481 atcttttagc cgctgatggt ttttcttcgt atattctgtt ccagcaagca tagcgatatg
      541 ttgcgcttta tgggagacaa agtgttcaat gactttttga acacttgact taaagtcgac
      601 aactagagag tcgattcctt gagaagtgcc gtcagaatct accaaaagca aggcattttg
      661 ggatcctttc atttctaata actgagcttc gtcgaatttt cctagtgcga tcgttccatc
      721 tgccggaaga tcactaatgg aatcccacgt ttctttcaat aaagtaacgt ttgcttcttc
      781 tgcctttttt tcgattccta ggcgaataga taaataataa agatcttcaa gctcttccgt
      841 atcgtcgtac cactggatca ggcgaagcgt ttgcttagta tttgctgcat ttttacgatg
      901 tttcgtataa tttaagcgtt ctgctgcttc aaaaattttt tgctttgtgg ctaagccaac
      961 ggaaagatca ggatcatagt tgagaactct tgaaacagta gcaggagaaa ctcctgccaa
     1021 ctgcgcaatg tctttaattg ttgccatttg tctctcctcc ttttttacgt ttataaaatc
     1081 gcagtaaatc gttcaaacgc tgcctgtcct ttttcatctc gcttgaatac tccagcgtct
     1141 tccagtacac gtgcaaaaac ctgacctaca gatttttgta cgacatcggt gaccgtatct
     1201 ttcgtcaaat caggatgttc tttttttaat tgttctgccc acggacgatg atattcagcc
     1261 atctggtttt cttctcctaa taagaaatgc tctacttcta ctagttctgg tttcaaacga
     1321 ggtggtaaaa cagcaagccc cattacttcg atcaacccaa tgttctcctt tttgatatgt
     1381 tggacatctt tatgtggatg aaaaatccca tcaggatgtt cttctgaaac attgttgtct
     1441 cgaaggacaa ggtccaactc aaagtaattg tcccttcttc gtgcaattgg cgtaatcgta
     1501 tggtgtggtg taccatctgc tgaaaaagct ctgatagata ctgtttcatc cgaatatgct
     1561 ttccattttt ccaatactga gttagctgct tcaataagca agtttttctc tgttgattgc
     1621 aaacggatca cagacatcgg ccatttcacg actcctgcga tgacttgcgg ataatcttct
     1681 agtttgataa gtttttctat cggtgctttt gccataggaa attcatgacg tcctgcctga
     1741 taatgatcat gagaaagaat cgatcctcca acaattggta agtcagcatt cgaaccaaca
     1801 aagtaatgag gcaagacttc agtaatccga agcagtctag caaatgtttc ctttgtgatt
     1861 ttcatcgggc ggtgttgttc tgataaaatg atcgaatgtt cattgtaata agcataaggg
     1921 gaatattgga atccccagct ttcaccgtct agattcattc gaataatccg gtgattggtg
     1981 cgggctggat agttcaagcg acctctatat ccttcgtttt ccatgcaaag catgcaggta
     2041 ggatagtcta cttttaccgc ctcgcgttct gctgcgattt gttttggatc tttttctggc
     2101 ttagataaat tgattgtgat ttccagttca ccatactccg actctgccgg aaatttgatg
     2161 ttttttgcga tggctcttgt tttgatgtag tcatttttct tacttaaatt aaagaaatac
     2221 tcagttgctt cctctgggct tttcgaatag tgctgtgcaa agaatgcatt gacgactgaa
     2281 ggtggcggtg tgagaaaatc cattaattgc gcttcaaaaa tctcttgttc tgctggcaat
     2341 tctgaaagaa caccattttc tcttgcctta gcgacaagct gatccaataa gtctacagat
     2401 tcttccttaa ctggtcttac ttcaatgctt tctagagcat cttctcctac catccctaaa
     2461 agacgattct gtaaatataa gcggtccatt tccatccatc cgccagcttc gatcgcaagt
     2521 gtggcaaaat cacaaatcgt ttgactgatt gacatatctc attcccctat tcttcataac
     2581 catttggatg gctgacatgc caatcccatg ctgttttgat aatcgctttg atatctgtgt
     2641 attcaggttt ccagcccaga atctctctcg ctttttcact tgaagcgact aatcggctag
     2701 gatctccagc tcttcttggt gctatttctg ctggaatttc ttttcctgtc acttctctag
     2761 ctgcttctag catttccttg actgagtatc ctttgctgct gcctaaattg aagaagttgc
     2821 tttcatttcc ttctttcaag tattccaaag ctaaaatatg tgcagcaatc aaatcttcta
     2881 cttgaacata atctctgata catgttccat ctggtgtatc ataatcgtct ccataaacag
     2941 ccaaggcttt tctttgacca agagctactt gtaaaatgat tgggacaaga tgcgtttctg
     3001 gtgtatgatc ttctccgata gatgcatctg cttttgctcc ggctacattg aagtagcgca
     3061 aagcgacata gcgcatgcca tatgcttggt cacaccactt catcattttt tccatcatca
     3121 atttactttc accatacgga tttttaggat tagctggtgt atcttctgtg attggagact
     3181 ctttcggctc tccataagtt gctgcagtag aagagaatac gattttattc acgttgaact
     3241 cgtgcatgac ttcaagtaag atttgcatac cgtatacgtt gttgttgaaa tacatcaatg
     3301 gtttttcgac agattctcct actaaagagc ttgcagcaaa atggattact ccttcaatcg
     3361 gttccttttc aaatacggaa cgtagaaatt ctttatcccg gatgtctcct tcataaaaat
     3421 gagcatctgg atgtactgct tgtttgtgac ctgtgagcaa attatctacc acagctactt
     3481 gatacccctt ttgaactagc tggtctacag cgtgcgaacc gatataaccg gctccgccta
     3541 gtactaaaat tgtcataaaa aacactcctt tgattagtaa aattgtgttt gttgattcta
     3601 tataatttaa aaaacgaagt ttacttttat ggtgaaaaca aacaaagtaa aatttcgtaa
     3661 attcatatgg taaatttata ataaaacatt tagtaaacat tttcaagggt tttttgcaaa
     3721 ggtttacaaa caaacgtaaa actagccttt ttttctcttt tgttccataa tagatataac
     3781 aaataataaa tgaggtggat tcaatgaaaa aatttgtatc tggaatatta gtaggaagtc
     3841 tggcaacagc cgctgccgtt gctggtttgg ttgcttctgt gaaaaaaaca gtgatcgatc
     3901 caattgacga aaaagaagca atgatcgaag aaaaccgtaa aaaagcaatg cgtaaacgcg
     3961 tttctcgtta ataattattt aaaaatacgc atgaagactt tctaaaaaac agataagtca
     4021 tcatgcgtat ttttatttgt cagtcaatat aagttgtgct attttatctg cctgtctcag
     4081 attccatgga tctgtataag gtctagctac tgctgcagtt agccaatcca caccttcaac
     4141 aggtattcca tagcaataaa agtcagactg gatttcccct gaagcatcaa tcacgcgatt
     4201 cgtacctcgc tcaacatcta tagcttctga atgataactt cctgtattat ctgaaaatga
     4261 aaaagggcga acaagtttgt tttccttcaa attttttatg acaggattac ttgaacgaga
     4321 aaagcttgtt tgtggcaatc gagcttcaat caaatagcga ctgctgattt ctttatcttg
     4381 tagagaaata acatagcggt tgtgcttttg ctgaatatca aatggcggtt cgatcaaatg
     4441 aaaaataccc gcatctatca gtgctgctaa ttctttcgtc cgaatgattg gcggaccgat
     4501 cgttaaaaag ctatttagat gagtaaacca tccccatagt atttctttgt attccttagc
     4561 agaaaaaacg tgccattcaa tagcctgccg gattggatca cgccagtctt ttaatgcatc
     4621 aaatgttgaa gcaaatgctc ctgtgcaatt gcctttttcc gcttctttta tctgcccttc
     4681 aataaatatt cggctagctt ctgaaaaggg ctcattctga taggcaagag gagtttctaa
     4741 atacgaccaa tcccatctat aagggattag tgctggatgc tttccgagac actcctctga
     4801 agagagggag agaaaatcat gctcaaaatt tttctttgga atcggcaagt gatattcttc
     4861 gatgattttc ttgtaataaa acaactcaac gtcttttttc agatagtcaa aaaatgtttc
     4921 gccagtcaaa aatcccgact gatgccattg ctccaggttt tcttttgtta gtaaccgtgg
     4981 ccatgccatt gctccgcctt gcttttgatt tcttcctcga gggtaataag ggagccccct
     5041 tcttgatcca ctgtatacaa tcggttcctt gcctgatgga tgatagacca gttttccctt
     5101 ttcgttctcg aagcgccctc ctcttgatac tgtaaacaat ccgacataat caaaaaaact
     5161 taagcctaga cctcttaaaa agacattttc tttaggcggt atcttcgaaa gatctacatc
     5221 tgcaggatta gaaggaagct gatacagtaa aacatttttc tttgcgtagt ctacccacac
     5281 tctttcttct tctgtctcat cattttccca gtgaccgctt gctaaaacaa gctgatcgat
     5341 agaatagctt tgctgatctg tctgtaaaag ataaccatct tttcttttgc ttactttttt
     5401 tactaaagaa taaacaaact gaatagaagc tggaaattct tcttgcaact ttgagaaaaa
     5461 ccagcgttga tagagtccgt ataaacatcg agtagattgc tgatcttttt ccagacgatt
     5521 gatttcttct ataattagtt gcttattttt ggttaccgtc tgttcgatat aatctgtagc
     5581 aggtccttta ctccattgaa acaagttggg tccctgtgtt accaatcctc cactggacaa
     5641 tgtttcatct gtaaaaagcg tcacttgttg agaaacagaa ttcattaata actccggtgg
     5701 ctgattcaac cgccaaactc gacctccagg accattggga tcgaaaagaa aaagttcaag
     5761 agaatgtctg tcctgattat tatggagaat cctttctgct acacttaatc ctctaggtcc
     5821 ggcaccaatg atccctattt tcatttgcat gcctccattt cgataaattt tttcaataaa
     5881 acagcatggt tctgatgttc attttttgca ccataaacaa aagtaatgac tggatgttct
     5941 ttcataagtt gactgagttt aaaaatagct tgcttctttt cttcttcgaa aatcaattct
     6001 tgctggtatt tctttgcaaa tgaagcaaat cgttctggta catggtcaaa agttttgcgt
     6061 gcttcattac taggtgcaat ttctttcaac cacagatcta actgcgcttt ttcttttgaa
     6121 attcctcgtg gccagaatct atccacgagt attctatagc catcctcttt ttcagcatca
     6181 aggtaaacac gttttaattt gatcatagtt gtttccttct ttctaccttt tcgcttagct
     6241 tatatatgta gataatagca caaaataaaa aaaatgaacg gcacaactat ccattgcgcc
     6301 gttcatgtga tcttggtcaa aatctaatga ttgattcggt ttttaaagct gtcatacaat
     6361 catctgtttt atactttttt acttttgatt tttccagacc atccgtcata tccaccctta
     6421 agtaaataaa tctcttgata acctgcttta cgtaatttat ttgctgtacg gatgctcaaa
     6481 cttttctttt gatcgtaaat atagacaggc tggtcttttc gaatagatcc taatgaatct
     6541 ttcaaaacag tgtaagggat gtttcttgca cctaaaatat gcccagcatc aaacacatct
     6601 ttttcgcgaa catcgattac ttgtgctttt ctcattcctt ctcgaaattc ttcttctgtc
     6661 aaagtcgttg ctgaacgttt ggccattact cgtagataga cttcccaaag gatgattgca
     6721 agcacaatca atagcaaaat gatattaatt acccataaaa ccatgtaatg cctccgtttt
     6781 tttaagcaaa tttcaaggct aatgaggcag caccaatgac accagcttca ttaccaagct
     6841 ctgctaattt gatttttgtt gattctctta cttgcgggaa agtaaattct ttaaaatatt
     6901 tctctacacg gctacgtaaa aattctcctg ctgccgatac tcctccacct aacacgatac
     6961 ttgacggatt taatgtattc cccaagtttc cgcaagctaa acctaagtag aagcatacgc
     7021 gatcaacaac catcaatgca aacggatcgt cttcttgagc catttcaaag atatctttac
     7081 ttgttacttc ttctccgttg tctagcattg ctttcagttt tgaatcccct gcgtattctt
     7141 ctgccaagaa acgacctagg cgtaccacac ctgtagcgct agatacagtt tctaaacatc
     7201 cgcgtttacc gcaagtacat tcgaaccctt caggatccac agtgatatgt ccgatttctc
     7261 ctccagctcc gctcacgccg tgaatcaaat ttccgccagc aacgatacct ccgccaacac
     7321 ctgttcctag agtaacgaat acaacgtctg gatcgttttc tccagcacct ttccatcgtt
     7381 cacctaaagc agcaacattc gcgtcattat cgatagcgaa tttgattcct gttcctgcct
     7441 cgatcagttt tttcacaaat tgaacttctg tccagtttaa gttatacgca ccaataaccg
     7501 ttccagcttc gctgtccacg cttcctgggg tacccatgcc gattccgata aagtcttcgg
     7561 ctttcatatt atataaattc aaacgatgat tgattgattc aatgatttca ggaacgatat
     7621 gcttaccatc atccaaaata ttggtatcga tgctccattt ttgctgaatc tctccttctg
     7681 gtgttaaaat tgcaaatttt gctgttgttc cacctaaatc aatcccaata atcttcttgt
     7741 ccattacaaa tttcctttct ttcggctttc ttcaattcgg tgctctcttt ttaatatgcg
     7801 ccacgctgtc atgtatgtat catgatcaat caaacggcta tcatacagat tacgcaattc
     7861 gatagtcatt aattcaatgt catagatgcg tgcacccaca tagataaaga tgccaaattt
     7921 tttgaacagc tgctgtacat catataagct ctccatcttt aagcacttcc ttcatattat
     7981 acaagtaaac catatttttt taaacccagt aaaatacata ttacaaaaag aaatacaaaa
     8041 actagtgtag aaagaatcct ttggtgtatc gaatagcttg tctgttgttt cggtagaccc
     8101 aaaacattcc ctaacactaa tccgccaatt agcccaccga catgtcccca aacatctaca
     8161 gaggtatcca gaagaccaaa aacaaatgtc aacacaataa ataaaagaaa atgtctgact
     8221 agctgctgga tcgctgggtt atgtttaaaa tgaaacccta agataaacaa cgcaccgaac
     8281 aaaccgaata tcgaagtact tgcaccacca gacagaacat tcgcttcgtt aaaagcaaag
     8341 cttgctgtat ttcccattat cccgctgaac atataaatca agaaaaaacg ccaatggcca
     8401 tagattgcct cgatttgctg ccccataaaa tacagtatca gtgagttcat tacgaaatgc
     8461 atcagtccaa aatggatgaa gattggtgtc actaaacgcc accattcatt gaagtgaaca
     8521 agataaggac catacattcc ggcataataa gggatctcaa gtcgcggaaa taattccatc
     8581 atgaggaaga ccgctgtctg tatccctaaa aaagcatagg tccataacgg tcgtcttaac
     8641 catgcacgca attttatttg ctgttgataa ttcatgaaaa cctcccattt cattttagtc
     8701 aataaacaat tgttggatct tctgatcaaa gctctccggt tgccattgtt cattcaattg
     8761 ttcacgaaaa acaaggctac atgttttttt atgaaaatta tttaaatacc ggtcgtaata
     8821 accaccgcca aaaccgattc gataaccggc tctattgtag ataatacctg gtacaatgag
     8881 gagatcgatc atctccggca aatagagctt ctctgattgt ggctcaagaa caccaaaact
     8941 cgaacgtaca agaacggact gttcatccat ttcataaaac gccatctgac gtttcggcaa
     9001 agttttaggt acaactattt tcttttgttc tttttctgct cgttggataa ccggctgtgt
     9061 atccagttca aattcattcg ataaagtcgt ccctatcact tttgctgact tccagtactc
     9121 gctggcgaat agctgtttat agattcgctg ttctttttcc tttttcttgc cacttttggc
     9181 cagatttttc agcttttcga ttcctttccg gcgtaatctt actttcaatt ggtccaaaaa
     9241 ctcacccttc cttctctcat aaaatggtat aggaaaaaaa gaaaaatagc aatcgaactt
     9301 tcaaataaat gcataaatag aataaaaaga agacctagaa atgattggcc ttcctttttt
     9361 aatgaatttc aactgttcag cgcgtgtttt tgtctgataa aaagtgcata cagaaaatat
     9421 ggcgcaccaa aaagggcaat caaaattcct gtaggtactt ccccacttgg tagaatcact
     9481 ctagcaacca tatctgcact aagcagaaaa atggaaccga acaaaccgct cagaacaaag
     9541 gtccagttat tttctttacg tacgactagc ttcgcagcat gaggagctag tagtcctaca
     9601 aaagataaac tacctgtcac cgctacacta ccgcttgcca aagcaacagc taacaacaaa
     9661 aggatttttt gacttttagc cacgttaagg cctaatcctt gcgcgcgttc ttgaccaaat
     9721 gatagcaata caatcctctg tgcataaagt cctcctagcg gaattaagat aaccgcccat
     9781 ggaagcaatg cccaaacata aggccagctc gcaccccaga ttgatcccgc taaccatgca
     9841 ttcacaaatc cataattttc cttagataat tggatcgtgc atagcaatgt taatgcagaa
     9901 aggccggcat taacggcaat accggacaat aagattcgat tcatacccaa aaagccattt
     9961 cgatcatagg ccgcaagata gacacagcaa gcagctaaaa caccacctag aaaggctaca
    10021 actagcaata gaaacggcag cgaatagtgc gaaaagaaac ctaaataaag catcactaaa
    10081 aatcctgctc cggcattaat gcccaatata ctagaatctg ccaattcatt tcttgttact
    10141 ccttgcaaga tataaccaga aacgccaaga caagctcctg ctaataaact gatcagtaat
    10201 cgaggaactc gaaattctct aacaatcagc gccaaagaag atgattcttt ccctatgaac
    10261 gtggcaaaaa gctgatccag gtaaataaaa ggcgtaccaa tcattaaact acctatagac
    10321 aggatgacaa gtacaaaaag caagaaatag aacgtccaat atattttttt caccgttgtt
    10381 ccctccttac ttgtatcagt aaaaacggaa cgccaatcaa tgcaatgact aatccaaaag
    10441 gtgtttcaaa agggggattg atcatcctcg ctgtaaaatc cgccaacata accaatccac
    10501 cgccaactaa aaaagagaca ggtagaacat aacgatagtc cgttccaacc attccgcgaa
    10561 caactggcgg aaccaacagc ccaataaatg aaacaggtcc gactaacgaa acggcaatgg
    10621 ctgctaacac tgcaactaga cagaaaacaa tcaaccgcgt tcgtttagga tgacttccaa
    10681 gagctaatgc atgtgtttca ctcaaatgaa tcaaagatat tgcttttcct aatgaaaaag
    10741 aaaccaaaac agcaagtata tataaaggaa acaatactgc taattgtttc catgtgatat
    10801 tggcagctcc gcctacaaac caaaaagcaa gatcctgctg cagattaaag aattgggtaa
    10861 gtgcttggct gatagcagta aaaaaagaac taatagctac gccagctaaa atcagctgta
    10921 aaggattcat gcccattttc gaaaactgca aaaaaccaaa tacgagcaaa gttacagcaa
    10981 aagaacctgc caatgacatt agaaacacag aaaaatcaga agctttaggc caaaaagcaa
    11041 aactaagggc cattgccaac gaagcacccg cgttgattcc tagtaagcct gaatctgcta
    11101 aaggatttct tgtcactcct tgcatcaatg caccgctcaa tgcaaaacaa ctccctacaa
    11161 gaaatgctcc cgccacacga ggcaaacgaa tatttcgtat gatttggtga ctttgttttg
    11221 atctatcaaa atcaaacaac gcctgccaaa aatctgcttt ttccacagtc gctgcgccat
    11281 ttgaaagagc aacaaaaaaa ataatcaaaa gaacaaaaca gaccaaaagc aggagtctat
    11341 ttttcttcat agtcctcata attgatcctc ctgctctttt ggcaacaaat cataggttag
    11401 aaaaactggt ttatttgttc ttggaagcgt gacaatcgtt gcatcaatct caaatatttt
    11461 tttcatacac tcttttgtga tcacttcttc aggtgtacct tctgtgatca acttaccgtt
    11521 tttcattgct aataaataat ctgaaaaacg tgaagcatga ttaatgtcat gaatcgacat
    11581 caagatcgtt gtttgtttca tttgattgat ttcagtcaat aactgtagga tctctaattg
    11641 gtgtgccgga tctaaaaatg ttgtcggttc atccaagatc aagatatctg tttcctgagc
    11701 aagcgccata gcgatccaga cacgctgggt ttgtccacca gacagcgttg cgatatcccg
    11761 catacgaaat ccagctagac ctgtagcatc caacgcccac tcaattgctt catgatcttg
    11821 cgtgtccatg ccactgaaca gtttttgata agggtatcgt ccgtaagata ctacttcttc
    11881 tactgtcata cctgtagggt gttcactagt ttgtgctaat aatgcaattt tttttgcaag
    11941 ttcttttgaa ctgtatgtag agatatcaga gttattgaca atgatctttc ctgatttcac
    12001 aggtagtata cgggtaaaac ttttcaataa agtagatttt ccacttccat ttggcccaat
    12061 caaactagtg attttccctt caggaatcgt aacagacatg ttttcaatga tttttttgtt
    12121 ttcgtagccg gctgcaatgt cagctgctct taatctcgtc atttcaccca tcctttcgct
    12181 gaaaatcatt ctcaattatg acgctgtttc aacatttcgt caagcgctac tttcatatct
    12241 atagccaaat gaagcggttg acagcgttcg aaatatcagg aataataacc aatgagaaag
    12301 attctcaatt atgttaggag gaaagaaatg aaattaaaaa caaaagtatt cacattatct
    12361 agcatattgc tgctggctgg agtactgagc gcttgctccc cctcttcaga taaagaaaca
    12421 gctacaactg ccaattcgac gacttcatcc aatagtactc atacagtcac agatacactt
    12481 ggacataaag tagagattcc aaacgcgccc aaacggatca tcggcagtta cttagaagac
    12541 tatctgattg cactagggga aaaacctatc gcccagtgga ctgttggcag tggttccatt
    12601 caagattatc tgcaagatga tttaaaggat gtcccaacga tttcttatga ccttccttat
    12661 gagaaagtgt taagctttga gcctgatttg ctgttgattt cttcttccgc tactgtcgaa
    12721 ggcgggaaat acgaacaata tagcaaaatc gcgccaactt atgttgtaaa aaacggaaca
    12781 gatgtcacat gggaagaaca actaaaagat gtcggcaaag ctttggcaaa agaaaaagag
    12841 gcagaaaaaa tcatttccga ttatcaaaaa tccatcaaga aaactcgaga agaactagca
    12901 gataaaatcg agaacaagac agctgcagtg ttgtgggtga ccaacaactc agcctttatg
    12961 gtcagcaaaa atcggtcaag tggaagaatc gtatacgacg atctggaatt tggtgttcct
    13021 gatctagtgg aagaggtctc caaaaaagcc acttctgact ggtctgctgt ttcctctgaa
    13081 aagctagctg aattagatgc tgactacatc atccttgtga acagtgacaa agatgctgcc
    13141 atgttcaatg aaccaagctg gaagaatcta aaagcagtga cagacaatca tgtactgcaa
    13201 ttcggacctg aatctagttg gctatataac ggacctattg ccagtcagga aatggtcaat
    13261 gatatcaaag aaaaactaaa ttgattttaa ctaaaaaaag catcttcacg attagtcgtg
    13321 agatgctttt tttcttatta acaaactaga cgcatagatt ttattcttct tttgaagcaa
    13381 ccctattttt tactctttcc catttttgaa aacgatgggc atatagattt tcttgatccg
    13441 ttatcccctc atactcctct ataagggcga agtctgaaaa atcaatattc ccaatatacg
    13501 tatcgccttc aaacgtgcta tcgatcaatg ttcgccagat ccgaccagtg taaggaagaa
    13561 gttcttgaaa aatccgacta ccacccgaaa catagatatc ttctgagatc gtttgactat
    13621 acgacaaaag ttcatcgatc gaatgcatta cttccgcatt ttctttcgtg cgaaaatttg
    13681 gttgcgttgt caacacgatg atatggcgat aaggaagtga aagatccccc attccttcat
    13741 aggtctttct tcccatcact aaaattcgat ccattgtatg ttcgcgaaag aaacgcatat
    13801 catttggcaa tcgccatggt aacaaaccat ttttgccgat cagaccattt ttatcttgtg
    13861 cccacatgga aataaacata ttatccgctc cttatgattt tagatgtttt gagataaaaa
    13921 aagtctcaat tctttgacca gcaaggaatt gagaacttta aaaacattat tttgtttcac
    13981 ggtgcaaagt aactttgcgt tcgcgtgggc aatatttttg tttttccaaa cgatcaggat
    14041 tgttacgttt gtttttgctt gttagatagt tacgttcttt acaagaagta cactctaaag
    14101 tgatgtttac gcgcatgttt ttccctccca tttttacaag aatcctctaa gatgactctc
    14161 agacttgatt atcttaccat gattttttct agattgctag tgtttttcac gattttgtta
    14221 agtaaaacta cttgacgata aatacaacgg ttttacttct caaacaaaat ctttttcttt
    14281 ttgtataaat acccttacac ttgtttatat agattatgtt ttttaataaa gggggatact
    14341 aatatgccat ggaacatgaa ggactttcct gcatcaatga aaaacttaga taaattgaca
    14401 agaaaaaaag caatcgacat cgcaaatgca ttattagatg aagggtaccc tgataaccgt
    14461 gcgatcccaa ttgccattga tcaagcaaaa aaatggtatg aagatgctag tgaatcagaa
    14521 aaacgaactt tcgaaaaaga aaaaaatcca agcaagacgg atgaacacga tacgaatcct
    14581 cgtgctggaa aactgcttga ttcagatgtg atcgtagaat atgaggaaga acaatggatc
    14641 gtgaaatcta aaggggcaaa aaaggcaagc aaccattttg atacaaaaaa agaagcaatc
    14701 gaaaaaggaa agcaagtagc acaaaacaaa gaatcaactt tgttcattta taaaaaagat
    14761 gggacaaaag aaaaagaaat cgattattga acatatgtaa aggggttgtg acgaaaatcg
    14821 tgtcacaacc cccttatgtt cgaaacaatg gtgttcctct gccaactccg aaccataagt
    14881 cataatatct ataaaacggg aagagctgtt ttttgaaatt gtttcttatc actcagtgtt
    14941 aaacggtagg agaaaacctc ttttttattg atatttgatt ttcatcaaac agtcacatag
    15001 tcgattgctt ctgcttgcgg aatcgtttca tctacaaagt agactttata ccatgtcaag
    15061 aaactgaaga ttgtccagat ttttctttgc tcttctttac gtccttcgtg atggtcatct
    15121 agcaacttca tgattttttc ttgatcaaaa aattcttttg caaaatctgc ttcgaataat
    15181 gctttgactt gttcgtagcc gtgttcttct ttcaaccaag ctttgattgg cacagggaat
    15241 cctaatttca cacgattcga ccattcttcc ggaagatgtt tgttcgcagc ttgtctgaaa
    15301 atatcttttg tgttgttttg attcaataaa aacttacttg gtatttgttg agccaatttc
    15361 atgacttcga tatccaataa aggtactcgg acttccaaag aacttgccat agaaagttta
    15421 tctgccttta acaagatatc ttttggcatc cattgatgaa gatcgacata ttgcatctta
    15481 ttgacttcat ctttgattcc ttctgttttc tcgtaatgaa cagtcatgat ttcatccaca
    15541 gatggtgctg tttgatattt tggtgttaac acttctgatg cttctgattc ttcgaacact
    15601 cgagcatgac cgataaaata ttcttttgca ggagcaagtg attcatataa atggatccgt
    15661 ccatggaagt ttttcatttt tccgatttta cgtcctaaat tatagcgtgt tccttttggt
    15721 aattttttca atccttgagc aatcacacgg atgaattttg aattcgtatg gaatccatac
    15781 gtttggtatc ccgcaaacag ttcatccgcc ccttctccag attggactac ccgcacactt
    15841 tgtgaagcaa gatttgctaa aaagtacaaa ggtacgcaag aaggatttga atcaggttca
    15901 tctaagtgat actggatcaa agggaatgct ttgaacgaca tgtctccgtc gatcactgct
    15961 gctgtattat ctaagtccaa tagttcggtt agttttctgg cttcaatcgc ttcattatag
    16021 gttttatcat caaacccgat tgagaaagaa tgatctggtt tcaatacaga ggttacataa
    16081 ctggaatcaa ccccgctgga taagaaagaa ccaacttcta catcactgac cgtatgtgct
    16141 tcaatagaag cttgaacggt ttcgtcgatt ttttcgatcc attcttgtcg ggaatgcgtt
    16201 tcttttgttt caaaatctgc atcccaatat tgctgaatgt ctatttttcc atctttatac
    16261 gtataataat ggccttcagg caaacgatag acatctttga agaatgtttc gccgtttaat
    16321 ggagaatatt ggaaagtcat ataaggtttc aacgcttctt tgttcaattc tttgttaaaa
    16381 tcaggatgag gcagaaaact tttgatttct gaaccaaaca taaatgttcc gttcatttct
    16441 gcataataat atggtttgat cccaaagtgg tctcttgcac cgaataactc attcttttca
    16501 ttatcccaaa tagcaaaagc aaacattccg cggatctttt gcaataattc tgttccccat
    16561 tcttcgtaac catgcaaaag gacttctgta tctgcatgtg tttgaaaaac gtggccagct
    16621 gcaatcaatt cttctctcaa aggctggtaa ttatagattt cgccattaaa aataatgatc
    16681 tttgtccgat cttcattgta aataggctga gtaccgccct ctaagtcaat aatacttaat
    16741 cttctgaatc ctaaagcaac atgtttatcg atatattctc ctgaactatt aggtccacgg
    16801 tgaacgattc gatccatcat tgtattaata attgtttttt tgttgtcctt gtcgttaaca
    16861 aaacctacaa taccgcacat ttaactttca catcctaata taaaattact gtttatttca
    16921 ttcatatgca tcttatcata gaataaatag cggacgaata ttttctctct tacaatttcg
    16981 tcacgtgaaa acaaaagatg aaagtttctg tttttacaga aaataaagtc ccaatatcta
    17041 atttaccatg ttttcttttt tgaggctacc ttattctctt cgtgttaaaa aaatattagt
    17101 ggatgctatt tccaaaaaaa ccagcaaaaa aagacacgac ctaaagatcg tgt
//
LOCUS       DAFLWZ010000058        17005 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000058 DAFLWZ010000000
VERSION     DAFLWZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.058"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..124)
                     /locus_tag="L1V38_002025"
     CDS             complement(<1..124)
                     /locus_tag="L1V38_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBN1316571.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="L1V38_002026"
     CDS             complement(228..539)
                     /locus_tag="L1V38_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1316572.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="L1V38_002027"
     CDS             complement(541..738)
                     /locus_tag="L1V38_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBN1316573.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="L1V38_002028"
     CDS             complement(1132..2859)
                     /locus_tag="L1V38_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBN1316574.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="L1V38_002029"
     CDS             complement(2852..4045)
                     /locus_tag="L1V38_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1316575.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="L1V38_002030"
     CDS             complement(4232..4876)
                     /locus_tag="L1V38_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1316576.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="L1V38_002031"
     CDS             complement(4970..5104)
                     /locus_tag="L1V38_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBN1316577.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="L1V38_002032"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="L1V38_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBN1316578.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="L1V38_002033"
     CDS             complement(7235..7708)
                     /locus_tag="L1V38_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBN1316579.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="L1V38_002034"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="L1V38_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBN1316580.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="L1V38_002035"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="L1V38_002035"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBN1316581.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="L1V38_002036"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="L1V38_002036"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBN1316582.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="L1V38_002037"
     CDS             complement(11755..12894)
                     /locus_tag="L1V38_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1316583.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="L1V38_002038"
     CDS             complement(13203..13916)
                     /locus_tag="L1V38_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBN1316584.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="L1V38_002039"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="L1V38_002039"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBN1316585.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="L1V38_002040"
     CDS             15105..16637
                     /locus_tag="L1V38_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1316586.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="L1V38_002041"
     CDS             complement(16828..>17005)
                     /locus_tag="L1V38_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316587.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgac aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFLWZ010000059        16714 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000059 DAFLWZ010000000
VERSION     DAFLWZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.059"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(251..1462)
                     /locus_tag="L1V38_002042"
     CDS             complement(251..1462)
                     /locus_tag="L1V38_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1316588.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1581..2216)
                     /locus_tag="L1V38_002043"
     CDS             complement(1581..2216)
                     /locus_tag="L1V38_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBN1316589.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2352..3005)
                     /locus_tag="L1V38_002044"
     CDS             complement(2352..3005)
                     /locus_tag="L1V38_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316590.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3108..3314)
                     /locus_tag="L1V38_002045"
     CDS             complement(3108..3314)
                     /locus_tag="L1V38_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBN1316591.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3390..4136)
                     /locus_tag="L1V38_002046"
     CDS             complement(3390..4136)
                     /locus_tag="L1V38_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316592.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4296..4520
                     /locus_tag="L1V38_002047"
     CDS             4296..4520
                     /locus_tag="L1V38_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBN1316593.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4544..5305
                     /locus_tag="L1V38_002048"
     CDS             4544..5305
                     /locus_tag="L1V38_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBN1316594.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5317..5574
                     /locus_tag="L1V38_002049"
     CDS             5317..5574
                     /locus_tag="L1V38_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316595.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5666..5917
                     /locus_tag="L1V38_002050"
     CDS             5666..5917
                     /locus_tag="L1V38_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316596.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5893..6066
                     /locus_tag="L1V38_002051"
     CDS             5893..6066
                     /locus_tag="L1V38_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316597.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6180..6587)
                     /locus_tag="L1V38_002052"
     CDS             complement(6180..6587)
                     /locus_tag="L1V38_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316598.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6748..6972
                     /locus_tag="L1V38_002053"
     CDS             6748..6972
                     /locus_tag="L1V38_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316599.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6982..7176
                     /locus_tag="L1V38_002054"
     CDS             6982..7176
                     /locus_tag="L1V38_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316600.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7179..8201
                     /locus_tag="L1V38_002055"
     CDS             7179..8201
                     /locus_tag="L1V38_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1316601.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8164..8979
                     /locus_tag="L1V38_002056"
     CDS             8164..8979
                     /locus_tag="L1V38_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBN1316602.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8997..9779
                     /locus_tag="L1V38_002057"
     CDS             8997..9779
                     /locus_tag="L1V38_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316603.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9779..10627
                     /locus_tag="L1V38_002058"
     CDS             9779..10627
                     /locus_tag="L1V38_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1316604.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10624..10866
                     /locus_tag="L1V38_002059"
     CDS             10624..10866
                     /locus_tag="L1V38_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316605.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11009..11377
                     /locus_tag="L1V38_002060"
     CDS             11009..11377
                     /locus_tag="L1V38_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1316606.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11392..11553
                     /locus_tag="L1V38_002061"
     CDS             11392..11553
                     /locus_tag="L1V38_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1316607.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11550..11876
                     /locus_tag="L1V38_002062"
     CDS             11550..11876
                     /locus_tag="L1V38_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316608.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11873..12688
                     /locus_tag="L1V38_002063"
     CDS             11873..12688
                     /locus_tag="L1V38_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBN1316609.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12827..13138
                     /locus_tag="L1V38_002064"
     CDS             12827..13138
                     /locus_tag="L1V38_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1316610.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13162..13380
                     /locus_tag="L1V38_002065"
     CDS             13162..13380
                     /locus_tag="L1V38_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316611.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13377..13793
                     /locus_tag="L1V38_002066"
     CDS             13377..13793
                     /locus_tag="L1V38_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBN1316612.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13790..14128
                     /locus_tag="L1V38_002067"
     CDS             13790..14128
                     /locus_tag="L1V38_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316613.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14125..14355
                     /locus_tag="L1V38_002068"
     CDS             14125..14355
                     /locus_tag="L1V38_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316614.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14362..14565
                     /locus_tag="L1V38_002069"
     CDS             14362..14565
                     /locus_tag="L1V38_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1316615.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14562..14858
                     /locus_tag="L1V38_002070"
     CDS             14562..14858
                     /locus_tag="L1V38_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316616.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14935..15348
                     /locus_tag="L1V38_002071"
     CDS             14935..15348
                     /locus_tag="L1V38_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1316617.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15361..15747
                     /locus_tag="L1V38_002072"
     CDS             15361..15747
                     /locus_tag="L1V38_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316618.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16298..16525
                     /locus_tag="L1V38_002073"
     CDS             16298..16525
                     /locus_tag="L1V38_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316619.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
     gene            16522..>16714
                     /locus_tag="L1V38_002074"
     CDS             16522..>16714
                     /locus_tag="L1V38_002074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316620.1"
                     /translation="MKLYYVEKANCWVVEGCLSKYATDIISTQFSELGLKVIFCGEFV
                     SVKEAVLPMTAKSRRSRGSS"
BASE COUNT         5664 a         2726 c         3485 g         4839 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtt
      121 cgttatttaa tggtatttta aatgaagata agcgaattta cagcattttt aaatgcttat
      181 ataccgcaaa ttatcccaag tttttgtata tcctacccga gtttataccc gaaaatataa
      241 ttttttagtg ttattttata tcttttttta ataggttttc aaacgctgta gttgctgtat
      301 ctttttcttt gcgtaagaca tggccataaa cattcattgt agtattaaaa tctcggtgtc
      361 ccaatcgttt ttgaagctct tttggagtca tattaggatc gctaagcaaa taggtagctg
      421 atgtatgtct aatgtcgtga aaacgaatgt gacgcaaatt gtgacgtttg gtgaatcgtt
      481 tgaacttctt atacagataa cttccacgtg gcaaagttcc atcttgtttt gtatcaaata
      541 taaaatagtg ttttaatttc tttatattta atttccaacg aatcttttta ttctctttga
      601 ttaattcatc taacatatca aatagataag caggaccggt tactattttt tcatcatcat
      661 catttttcaa acctggcagc aaccgaatat ctgattttcc atccacttct gaaatccgct
      721 gatgaaatct tatttcttgt ttgtcaaagt caatatcttt ttcttctaaa gctgcaattt
      781 ctccttgtct tgctcctgta ataaatgcta gaacaattaa agttttaatt tctatgcttt
      841 cctcaaatgc tgcttttagc attgcatgaa tttcttcttc cgaataaggt tcttcgatat
      901 tcttttttac gcctttttct tttggtattt ttacattttc cacaggattt tctttaattg
      961 ctccgtactc atttttagcc atcaaaaata agttgttaac ggcgtataac atacgaagct
     1021 ttgtatttct tgataaaggt ttatcagagt ttctcccagg atcttttgta ttgattcttt
     1081 gagcattaac aacaattttc tttatcatgt atggtttgat atcgattaga gggataaaat
     1141 caaatttatc aagaaatcta ttctcgatca ttcgcttata gttatgataa gactttggct
     1201 ctaaattttt ttcggcctct gaaagccata tttttctata aaattcacca aaagttatat
     1261 tgaacaaatc caacgaatca tcggtcattc cttcgaattg ctctaaccag atgttcaatt
     1321 ctttatatgc cgctctttta ctacttgctt ttatagtttt gctttttctt tttgccgagc
     1381 catcaggttt gtatcctaat acagctctta gtctatatgt ttcgttgtct acttgttcta
     1441 agtatcctgt tacttctgac ataattgaat cagctctctt tctctgatac aataggtact
     1501 ataaagaagc ctatcgtata ggtttgtttc tttcttagaa cacgctcgct ttggtcggtg
     1561 gggcgtgttt tttatactaa ttagttgtga agagcaattg aaactgtctc tgttccaaag
     1621 taacctgttt gtgcttgcaa tacattattt tttgcatttg cttgggcttc agagatatca
     1681 aaaactattt taccagtttg ttgcatatca ggatttaagc tttccataaa gaaagagtta
     1741 gtgatattac cattttcatc ttgatttgcc gacatagatg cagccgaatc agcttcgaaa
     1801 gtttttccat ctgcttttaa tttgaagaat gagctatcaa cagtcacagc cttatcacct
     1861 gcatttttta cagataagtc aactactaag aaagtgtctt ttgcgttagt aggaagtaca
     1921 gatgggccaa cttgttttac tacttcaacg gagtttactt tgtattccat tttccctaca
     1981 gcaacgtcat caccgatttt ataagtcttt tcttcttttg ttgtagtttc ttttgtagtt
     2041 tctttattag tacttgttga tgttgcagta gctgaatctt tgttttcacc gccacttaga
     2101 gcaccaccaa taccaaaaaa caaaagtact attaataccc aaaaccatac ccgtttataa
     2161 aacggttttt taaccttata cattttccca tcttgaccca taactttttt tgccatttaa
     2221 atattcctca tttcttgtta taatatattt gtgatctcag aaatgaggta tgagtccgtg
     2281 ttgcagcacg ggctttttta tttataactt ttttagagat tataggcaaa atagtagggc
     2341 ataaaaatat attattgaat tccgtattta aaaaatccta attgaacttc accggaagtc
     2401 ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc cattctgtac tttccatgca
     2461 acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg ataaagtgtc agcgtcttgc
     2521 tgagcgcttg tttgttggtc ttctggattt tgttgagatg ctgcttgttg ttctttctga
     2581 tcttgactga taatattgcc agcatcatct gtagtcaatc cattttcata aagggccacg
     2641 ccgaaagctt cccactcttt gttggaccaa tttgcacgat cagctggagt tgactgtaaa
     2701 gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg cggtttggat tgtactctga
     2761 ctggagctta taactgttgg gctaggttcc gccgtaactt ggttggagct tgtaactgtt
     2821 gaactagaat ctgttttaga tgtagatttg ctagtagatg aactggtttc agttgtttct
     2881 tttgttttac ttatttttgt ttcttggtta gaagtggcat ctgttgattc agctttttta
     2941 ttatttgaac aagctgaaag tagcagagca gtacttaaca acaacataac gctaactttt
     3001 ttcattttat actcctcttt tctttgatac aataagttgt aaagaagcct actataggtt
     3061 taacatccca cgtccacaaa ctttggtcgg tgggcgtgtt tttttgttta tagactttcg
     3121 aaaactaaag tagcttggat tctatcgcca ccaccgaaac ctttactacc accgtttgta
     3181 gtggaaatag tgtgtaatcg ataaccttta gaacactgtc tatttatagt gttttcaagt
     3241 tctgataggt tttgcgaccc ttttcctata aacttttctt ttaatacaac ttgcaataca
     3301 acgtaacttg gcatattctt ttccttcttt ctactatgat aataaatact aacccctagc
     3361 cggagcgcca actacgactg gggtattttt tagaatacga ctttcccgat tattctaatc
     3421 tgttccggtg agacgactct atcttcatat aattcgttta tagagcgtag aataatcgtt
     3481 tgactctcat aatccttata tacttcttta cacgtcacac cgtcaccatc tatttcaacg
     3541 atagcaatct caccgtcttc cacgtctggc tgttccttaa caaatacaaa ttgtccattc
     3601 ctgataactg gttccattga atcgcctata ataggaacag caaaatcagc attgtttgga
     3661 actctttcaa attcttcttc ctctacaact gtatcgccat aaactaattc agtcgggttg
     3721 gcggcagaag ctgaattttt gattgtcgga agtttttcct ttttaggaaa gtgcaccacg
     3781 tttcctcgat tttgctcttc gagttgctgt tcagcaaagt tgtagacttt tgtttgtctt
     3841 ggtttttcta attgattgta gattgtttca atggatggaa tgttattttt cttatcttct
     3901 ttaggaacat cgtaaccaag caaccatgcc tcactcacat ttaaagtttt agccaacaaa
     3961 taaagcttgt gttggtcggg cgatgactta ccattgacat attgcgatag atgacttttt
     4021 gacattttta ttccagtttc tttttgcaaa ggtaaagaca tattcaaaat atcaacttgc
     4081 tttaaatttc tttcagacat taactgatta agtcgttgct gagtcgtttg cttcatctta
     4141 tacctccttt ctgatactta ttatatacct tattgaacat aagttcaata aaaaagttaa
     4201 attaatttga acttttatgt tgacaatgtt ttatgcagga gttatacttt ggttacaaag
     4261 ttcaaaacat ttgaactaga aaggagcgaa ctaatatgag ttttgattat tctaagttgt
     4321 cgggaagaat tgttgagaaa tatggaacgc aatacaattt ttcaatcgct ttaggtttgt
     4381 cggaaagaag tttgtcatta aagttgaata accgagtacc atggaaaagc accgaacttc
     4441 aaaaagccat tgaattgcta gatattccaa aagaagaaat tggcgaatat ttttttaatt
     4501 tagaagttca aaatgtctga acttaagaaa ggaattcgaa aaaatgaaca cacaaaaatt
     4561 tgaaaacaat ctatttgaat tagaagttaa gacggaaaat ggtgaatcgt tatttaatgc
     4621 tgaaacagta gcaagaagtt tgggtttcgt ggaaacaaaa aacggtaaag aatatgttcg
     4681 gtggagaact gtcaatggat atttaaaaaa atacctttcg caagaagttg cgaaaaacga
     4741 ctttatcagt gagccaatgg tttacaaatt agcctttaaa gcaaacaacg tacttgctga
     4801 aaaattccaa gactggttag caacggaagt cctacctcaa atccgaaaac acggcatgta
     4861 cgcaacagat gaactactta acaatccaga cttgctgatt gaagtagcaa ccaaactcaa
     4921 agaagaacgc acgttacgat tgatagctga acaacgagta aatgaattac aaccgaaggc
     4981 agactattac gaccgaatct tgaacaacaa aggattagtt acagttagta cgattgctaa
     5041 gaactacggt atgagcgctg tatcgtttaa taaattgcta catgaattag gtatccagtt
     5101 caatcaaagt ggcacatggc tgctatacag taagttccaa gacaaaggat acacgcatat
     5161 tgagccattt gattatgaag ataaaaacgg caatcggcaa gtaaaaacaa ggatgaaatg
     5221 gacgcaaaaa ggacacatct tcttatatga aacattgaag aagaataatt acttaccgat
     5281 gattgaacgt gaacaaacag cataggaggt aacactatga acgaggaaat gagccaaaca
     5341 atcaaggtac aaaaaatgat agatgatcta acacatgcaa ttgatagcca agccgataaa
     5401 atcatcaagg aattgcaagg acaaaaagtt tgggatgcaa aaatgctttt caagactatc
     5461 aaatttgaaa tgaatccaac aaaaagaaag ctcgccgatg tgttggaaga aaagttggct
     5521 tccgctatca acgagcaaga attactattt gaaaccgata cttttaacag ctgatgtttt
     5581 atagatgaca gtttcatccg aatctatatc attatagatt cgattattgc aatgtacgaa
     5641 ttataaatac aggaggaaat aaccaatgga gcaactagct ttagttaacc tctcagacct
     5701 taaagcttct ttggcagaat ctgagattgc aaatgaagtg tgggatacaa agcaagctgc
     5761 ggaatattta aaaaccacaa cacgcacgct gactaaagat gccgaatctg gaaagattcc
     5821 agcagcgaaa gttggcagag agtggaggtt tagtagtatc gctttgtatc agtatctaaa
     5881 aggaggaaaa acatgggtaa attcaacaga gcactagtgt tcagcgcacc cctaatcgtc
     5941 tatgctttag gactttgggg aagcagacaa gcattaatcg gcacgatcgt ttacatggtt
     6001 tggattttta tggggcttga tgaagctgag tacagagcga aaaagcccac cgagggggct
     6061 gactaaagtg tggttctgtt tattaggtgt ttatctcgtg gccgttttag taaataacta
     6121 catgagaaaa cgtggcgaat actggtatac atcctatgcg gttctagtat gtctaatgct
     6181 tacaattttt ctaatgattt attcaaaata ggtaatactt tgtcaatcaa ataagtttca
     6241 agagattttt gttctgcatc agtgttgccg taaccaaaac ggcttaagaa aattttcata
     6301 acctctatat cttcattttg aatatatggc aggactgcat aacctgatgc ttttacagca
     6361 gatatatttt tatcagtgtt actaccaata caaataccca cattgttgag aaatgttgag
     6421 aaagttgttt gtattgtttg ggtttttgaa tcgtgttttt gtaattcaat ttctttatcc
     6481 ttcatcgatt caacatgctt attatttata accgctgtaa tcgaagggga tataagagct
     6541 actaaagcta ggataatcga aattgtgatc gtgttatcga aactcatttt ttcaccatcc
     6601 agtttttaaa ccattatatc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     6661 aaaaataaaa aaagacacga acgccagcaa gcatgatcgt gtccaaaaga aaaatctttt
     6721 aaaccattat aacacaggag gaaataaatg atctcagtta aagggttagg cgatgaaata
     6781 ttcgaagcaa tgatgagcaa agcacaacag gacatcaaag aaaaaatcat ttctgctgca
     6841 gcgcaaggac aaactagctg cactgttcga tcgagaggaa cgacaccaag ttttcttttg
     6901 gcgctagaag atgaaggcat tttgaatatc aaacgaagag atggcagcgt cagattgttt
     6961 tggcaatttt aggaggccgt gatgaaagat tttgattctt taggcgccag acagcaacca
     7021 ccaaatgaag ctagtcctgt tggagttgat tggcaagaaa atccgttata tccaggtgat
     7081 acttgctatc taacagaaga aggctatgta ccagtagacg caattctaga gtacgtccag
     7141 caacattatc caaagattga attaggagga atttaggaat ggcaaatgat ttaacacaaa
     7201 caacacaacg ttcattagat gagcaggtaa tcagtaatct tggacggtta caagaacaag
     7261 gtttagaaat gccaccagga tatagtccac aaaatgcgtt aaaaagtgct tttttcgaac
     7321 tcactaacaa tacaggagga aacttgttgc agatggctgc aaacaatcaa gaaatgaaaa
     7381 cctccatttc taatgcactt ttagacatgg ttattcaagg gttatctcca gcaaaaaaac
     7441 aatgctattt cattaaatac ggaaacaagg ttcagctaat gcgttcatat tttggaacaa
     7501 tggcggtcct tgatcgtgta actggagggg cagatattac gcctgtagtc gttcgacaag
     7561 gtgatgagtt tgaagttgca atggatggac caaacatggt tgtcaaaaag catgaaacaa
     7621 aattcgagaa tttagacaat gaaatcattg cagcctatgt agtcatcaag ttaacaaatg
     7681 gtaaagagac cacaacagtc atgacgaaaa agcaaatcga tcaaagttgg gctaagtcaa
     7741 aaatgaaaga ttctggaccg caaaaggaat ttccagaaga aatggctaaa cggacagtaa
     7801 tcaatcgggc agctaaaaca ttgatcaaca caagcaacga caacgattta ttagttcaag
     7861 ctgcaaaaga tacgttagaa aatgaatttg acaatgatcg gaaagatata acgccacaaa
     7921 cagaaaaagt ggctactctc gaacaaaaat tcttttcaaa caaaaagatt actgaaccaa
     7981 tacaaaaaga accagatccg attgtgattc cagatgatat ccaaaatgaa gtaactcgag
     8041 ttgctgatgt acctgcccat ccagaaatag agcaagcaca tttgatcgaa aatgaggata
     8101 tcaatccaat tcaagaagaa ttgatagata ttccagactt tggacgcgag gaaggtgtag
     8161 aagatgtctc agaatttgaa gacgacgagt accctttctg atgagaatta ttactccaat
     8221 gaagctgact ggcagtacat gtcaacatca caatataagt cctttttaaa atgtgaagcc
     8281 gcagccttag caaagttgaa aggcgattgg gcaccgacgt cggatcccaa agccttactc
     8341 gtaggaaact acgtacattc ttattttgaa tcaaaagaag tacatgaagc gttcaaagaa
     8401 gaaaataaat ccaaaatgtt ttctagtagg aagccgtatg gattgttgaa agatttccaa
     8461 attgctgaac aaatgattga acgacttaag caagaagaag cattcatgaa catttatcaa
     8521 ggtgagaaag aaacgatcgt gactggggaa ctatttggaa cgacatggaa aggcaagatt
     8581 gattgcttga atgttgagga tgagtatttt gttgatatca aaacaaccaa agacatgcat
     8641 gagcggaaat ggaacgaaaa ctacggatca agagaaacgt tcattgtcaa ttttggttac
     8701 gtacttcaaa tggcaatcta tcaagagctt cttttacagc aatacggaaa gatgttcatg
     8761 ccaatcatcg ctgcggtatc gaagcaaacg cctagtgagg cgaagttgat aacgattgat
     8821 caagataaga tgagctacga gctaatcatg ctaaaagaaa atattgaaag aattgtcaaa
     8881 gtgaaaaatg gcgaagaaag gccgatacct tgcggtacgt gcgagtattg tcgaggtaac
     8941 ctttcaatta ctggattcac tagcatggac gatctttaaa aggaggtgct ttgcgaatga
     9001 atctaggata catcaagtta taccgtaaag tgactagttc attcgtttgg accaattccg
     9061 atatgttcaa gctatggata ttgtgtttaa tgaaggctag tcatgaagat agaaaatttt
     9121 tatttaacgg tcaagaagta cgtttgacaa gcggacaatt cgtcacagga gcccatgcaa
     9181 tagcaaaaga gtacaacgaa ggagtcccga gtgacaaagc aattgcatgg cgaacgctat
     9241 ggagatggct taagaaattt gaaaatgaag aattattgac aatccaatcg aacgctagat
     9301 atagcgttat aacaataata aattggtctg actatcaatc gagtgacaag ccagtgacaa
     9361 gcgacggaca atcgagtgac aagccagtga caacaaacaa gaatgataag aatgataaga
     9421 atgataagaa taataatcct cgcaactctc gaaaaacacg agagtatgca gatgacgatc
     9481 caaataaaaa attggccatt cttttattaa aactcattcg aaagaatcgt agtctcaaag
     9541 aacccgattt gaacaaatgg gccaatacga ttcgtttgac gattgaagct gacaaacgaa
     9601 ctggaaaaga agttcaagac atgattgttt gggctactaa ccatgatttt tggtccacag
     9661 tcatttcatc gccaactagc ttaagaaaaa atttcgatac aatggtgggt caaaaaaata
     9721 aaagaaagca acaaaatatt tctaatgatg agttaccaga aacaggtgag gattggtaat
     9781 gaataaaaaa ctaagtgcaa tggctgcacc ttacggcgga ttaaaaacag cagatcataa
     9841 ttgcccgaaa tgtggtgatc cattgtatat ctggaaaaca aaaaataaag atggtactga
     9901 tcgatgcggt cctacatgta tcaataagat ttgtggttat cgagaaatgg taactaaaaa
     9961 tcaaaaagaa gctatccaaa aagcgaatga agcaatgaaa aaggacgcta tcaatcgaat
    10021 gcttaacagt tcaatgatta cagatgatgc catatggacc ttcgattttg atggatacaa
    10081 agtagttgat caggaaacag cacaaataaa agcgatggct caagaatggg ctaaaaaaat
    10141 tgtaaatggt agcacgattc atgcagtgat aaccggtaga acaggagccg gcaaaaccca
    10201 tctaggcgct gcagtgatta aagaagtcat gagggcatct aattataaaa ttgcttgttc
    10261 atttatcagt tatcgagaac ttttagaaca gttgaaattt gcaatgaatg atccagaagc
    10321 aagaaaagcc gtaacaggtt cgctgatggc tgagataaag aaatcagatt tcgtggtaat
    10381 cgacgatttg ggtgcagaac taggaagaat ggaagaaaac aaccaggcaa cgccttatga
    10441 tgttgatgtt ctcacatcgc tcacagaagc tcgtctaaac aaagctacga tattcacaac
    10501 caatttatca tcgaagcaat taaaacacgc gtacggtgag cgagtgttct ctcgtgtaat
    10561 gaatggaacg aaagggaaca tagctgtatt caaaacaacg acagacaaaa ggaggaatcc
    10621 agtttgacct ttgtagtgaa aaaaatgtgc tacttagata gccgagggcg aggagaagct
    10681 agtgtcgagt ttgctaaaca ccacacgact aaagaagagg ctgaccttgt tgcaagtgtt
    10741 tgtggcggcg aagtagtcga agttattaaa cccaaaagac gattttcaaa acctaagaca
    10801 aagccagtga aaaaagagtg ttgttgtccg aaaagtaacc aagcatggat gagaggtgca
    10861 aaatgacttg tttaaaatgc aacgatgaaa cagttatttg gtataagaca ttgcttggat
    10921 ggtcaacttg tgaaccttgt ccaatatgca atgaaaatgg acgacgttcg aaagaacgac
    10981 tcgaaagact aaagaaggag tatagcaaat ggcaacaaga agcaaatacg gaaacaaaaa
    11041 gcacgaagta gacggcatca cttttgattc tatcacggaa gcagagtatt acgatctagc
    11101 cttgtggcaa gcacaggcga atggttggaa agtgaagctc caggaaaggt ttgagctgat
    11161 gccgaagttt gaactagagg gcaagaagta tcgcaagatc gagtatattc ccgacttcac
    11221 attttacaaa agcggcaagc tggtcaaagt cgtagatgtt aaggggatgc agacaaaaga
    11281 ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga tattagccaa
    11341 aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat catgacaaca
    11401 gaagaagtga ttcaaatgcg aattcgaagc cttcggcgtg agattgacga tctggaacga
    11461 acaaaggcag tgatggtcaa tgaaacggct agaaaggcaa tcgatttgca catagagaat
    11521 ttaagaaggg aaatccgtag attggaggaa tgagcgtgga taaggaagcg gcttggcgaa
    11581 aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg gttgctgaag
    11641 ttcagcgtct aggaaagatt gctaacggac gtatacgaaa aaagccagac aaaagaaaac
    11701 agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa aattttgatg caaggaacag
    11761 ctagtgagct gtctgcagaa actggatata cgcgtgggac tattcgaacg tacgcttggc
    11821 gaaatcacac cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa aaatgaacga
    11881 aaacaaatta atcaaattgg gtgtagcagg agcagtaatc gtaggtattg gagttatcgg
    11941 aggatttaag ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa
    12001 cggcggtatc aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt
    12061 gatccaatat ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag
    12121 cgacggcaaa aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc
    12181 agcaaaaatg tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt
    12241 aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt
    12301 cctttcagga gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt
    12361 tgaatctaaa gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga
    12421 aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct
    12481 agacgcagaa actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc
    12541 agaagcagag gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg
    12601 ttatgaagaa gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac
    12661 tgtagttacg gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt
    12721 tcttaggttt agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca
    12781 aagaagatga caacaacgat gaaatgaaat tttaggagga gaaataatgg acgaactaat
    12841 cacaaaagta gagcagtggg ctaaagacaa gggactggat caagcagatc caaaagcaca
    12901 gtttttgaaa gtagctgagg aattcgggga aatagcttcg gcgatggcaa gaagtaatga
    12961 tgaactattt aaagatagcg taggagacgt tatcgtcacg ctgattatcc tttccatgca
    13021 aaaagggaca aacgtacaag agtgtttaga aatggcatac aacgaaatca aaggacgcac
    13081 agggaaaatg gtagatggtg tattcgtgaa gtcgagtgat ttggagggca gcaaatgata
    13141 aaaaagctca ttcaattcag catggattta tatgatatcg aatcaggagc aacactatct
    13201 gtggaatcgg accatctaat cataaatttt ggtggaaagc gccagattat tttgtgggta
    13261 gttgatgatg tactgtttcc agaaattgtt catgatttcg aagaatcaaa agcggttgag
    13321 tttgaaatag tgaaaaaagt aatggaattg attgaaaaat acgaggagga cagcgaatga
    13381 taccgaagtt tagagcgtgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc
    13441 attttactaa aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga
    13501 aatcatatca cgtgcgaaac atcgacctca tgcaatccac aggaatgaaa gataagaatg
    13561 gtgtggatat atttgaaggg gatatagtat tagtcagcgt gcgaaatggc ttcgattact
    13621 tagataataa agtttgtatt gtcaaaaatt caatagatta ttccggatta gtttgtgcca
    13681 ctgttgatga agacttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt
    13741 atgaagtcat cggaaatata tacgagaata gcgagttatt ggaggtagag tgattatctt
    13801 agctactgac tacatcgatt ctttaaaaga tgaaaatggg aatgtcccag cattgctaaa
    13861 ttgtggaatt aaaagcaaga atagaatcat tttgttacgg atatcggctg atttagcaaa
    13921 atatctttat ctgagcaaga cagcagtata ttacactgcg gctacacgtt atcagtacaa
    13981 gggaaaaaca atcagtcagg attattatga tcgtttaatc agtcctgata tgtatgggaa
    14041 ttcagaatca gcaattaagc tgtttggcgc aatagagata tatgccgatg attttccaaa
    14101 tttatggttg aaggaggaag cggaatgaaa tacgaaatac cactaagtga agcagacgtc
    14161 cagtcaatta ttaacggtcg ggaggttaat aaaaaacttc ctgatggtac tgaattagtc
    14221 atcagacaaa gttatttgaa agatatggca gctccagtat taattgatcg ttttaacgtg
    14281 actgattctg tggtagagaa ccacttgaaa gaatttcgat caagtataaa cgacactttc
    14341 agattaggga gttgattgac aatgaacacc agacaccgca gagtagcaaa actaagaaaa
    14401 caggaactga atgtactaaa gacaaagttt gaaaaagaat atggaatttc agcagaagaa
    14461 acatataaag tggcaagtca gtgtgttgct gatgcaagtg atgctattcg taagtttgga
    14521 atttcgatat taagtgatga tcgtaaatgg gaggaaaaag aatgaaacta aaagacggat
    14581 tttacgctag cagtcacggt atcggcggtt taatgctaga tatgccgaca aagaatccta
    14641 aaacacgtaa gaaaccaaaa gtcaaagtcg gtgacatggt ccgctgtgaa gcagaggagt
    14701 tcatttatcc atttcgtgga tatgtagaac acgtctataa tcactcagcg atcattcgca
    14761 ttgaaaacac gatggaatgt gataaatgga cagctaaaag caaagagaat ttagcagtag
    14821 tgagattggt ggatatggaa ctaatcaatg acaaataaaa aagccggatc gctccgacta
    14881 acataataaa acagacaagt ttattatatc acataaaagg agcagtttga attgatgcaa
    14941 ttgttacgag aggtagattt caaacagaca agatgtaatg cgagagatgt gctgaagaac
    15001 tttcggcgtt tggagcggat ggcaggtcgc tctttgatag atattaagtc gccgattatt
    15061 acggatatgc cgaaggcacc gaagcacggc aataaggcag aggatgcatt gattcagatg
    15121 atggatatag aagcggagag agacgcgatt ttagcggctt tgatggctct tagtctgatt
    15181 agtcgtcaga tactctacta cagtttttgt gtgccagaca gcttctcaaa ctacagaatt
    15241 agccgtgaag tgggttattc agaaagaagt atacaacgga tgaaatcgga agctctaata
    15301 gagtttgcag aagcatataa acacggaaga ataattgctt ataaataggg ggaccatata
    15361 atgtggaaag attatgtatc gttgaaagag ttgaaaaaag atcttgtttt caaaagaatt
    15421 gtagaatggt cagagagtga attaatttta gaagatggaa ccaaaatgga agttgtatgt
    15481 agcgaatcag attgctgcgc atgggccgaa ggtgaattca aaaatgtaaa gcttgatgca
    15541 gtgattacag atataaagat ttttgataaa ggtaaccgtc tctataatgg tgacggacat
    15601 acctcttatg ctgaagtcgt tgtttatcat aatcgtaatg agatcgctaa agcagaatgc
    15661 acagcgaatg atgggaatgg cggctactat tatagtgttt gtgctttaaa ggtcaaagac
    15721 aaactttgta tagtgactga cgcataaaaa aatggcggtt ttttggcgga atgatggcgg
    15781 tttttagcca tttatcagtg atattatggt agtgtcgaaa gattagtgat aggtctgaga
    15841 caaaataata ataaaaggaa catcgtttta ttattgtttc acaattaagc ttcgatagac
    15901 agcaacggaa atattaagaa taaggatgtg aattttaact ccttctaaat tgttcttatt
    15961 atctatcatc cgttgctgtt tattgttaca tacagatcgc ttaggcggtc tttttatttt
    16021 ggccgaaaac ctacattttc gatggccgat tattggagga ggaatagcat gttcaaacta
    16081 tctgaaatca ttaagaagtc cgacgttgag aaattagaga tgttaaaaaa gaagttgaag
    16141 aaatagcagt ctcttcgtga ggctgtttta ttttgctcac aaaaatagac cactatcggg
    16201 taatagtggt caggaattaa atgaaaaaga tgttagggtt gttagctaag tataacatca
    16261 taacgcttac aaaacaatgc aagaaggata aattattatg agaacttact ggtatgtgtc
    16321 attaaacaat aaatatccga agccaatgaa aggacagcat aggcgtgtag tcatgtctgt
    16381 tcaaatgaag gcgaagtatt cgattgtaga aatgctaaga gaagctacac caaaagagat
    16441 tgatcagtat aagttggttc ttattggcat tggttggttt aaggatgaac atattcaaac
    16501 aaacatgaag aggtggttga gatgaagtta tattatgttg aaaaagcaaa ttgttgggtg
    16561 gttgaaggct gtctgtcaaa gtacgctaca gatattatat ctactcaatt ttcagagttg
    16621 ggattgaagg ttatcttttg tggtgagttt gtcagtgtga aagaagcggt attgccaatg
    16681 acagcaaaga gcagacgctc gcgtggttca agtt
//
LOCUS       DAFLWZ010000060        16667 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000060 DAFLWZ010000000
VERSION     DAFLWZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.060"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1396
                     /locus_tag="L1V38_002075"
     CDS             <1..1396
                     /locus_tag="L1V38_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1316621.1"
                     /translation="EKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNY
                     EGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPA
                     LPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNP
                     EGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSS
                     DEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKV
                     DVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPN
                     AEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSN
                     KKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGT
                     LGLLGYKNRKKENE"
     gene            1530..2873
                     /locus_tag="L1V38_002076"
     CDS             1530..2873
                     /locus_tag="L1V38_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1316622.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2985..4388
                     /locus_tag="L1V38_002077"
     CDS             2985..4388
                     /locus_tag="L1V38_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1316623.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            4737..5369
                     /locus_tag="L1V38_002078"
     CDS             4737..5369
                     /locus_tag="L1V38_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBN1316624.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5957..7396
                     /locus_tag="L1V38_002079"
     CDS             5957..7396
                     /locus_tag="L1V38_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316625.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7691..7909
                     /locus_tag="L1V38_002080"
                     /pseudo
     CDS             7691..7909
                     /locus_tag="L1V38_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8158..8373
                     /locus_tag="L1V38_002081"
     CDS             8158..8373
                     /locus_tag="L1V38_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316626.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8590..8846)
                     /locus_tag="L1V38_002082"
                     /pseudo
     CDS             complement(8590..8846)
                     /locus_tag="L1V38_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9033..9944)
                     /locus_tag="L1V38_002083"
     CDS             complement(9033..9944)
                     /locus_tag="L1V38_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1316627.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9963..10967)
                     /locus_tag="L1V38_002084"
     CDS             complement(9963..10967)
                     /locus_tag="L1V38_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBN1316628.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10964..13087)
                     /locus_tag="L1V38_002085"
     CDS             complement(10964..13087)
                     /locus_tag="L1V38_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1316629.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13092..15539)
                     /locus_tag="L1V38_002086"
     CDS             complement(13092..15539)
                     /locus_tag="L1V38_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1316630.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15526..15915)
                     /locus_tag="L1V38_002087"
     CDS             complement(15526..15915)
                     /locus_tag="L1V38_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1316631.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15975..16478)
                     /locus_tag="L1V38_002088"
     CDS             complement(15975..16478)
                     /locus_tag="L1V38_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1316632.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16491..16652)
                     /locus_tag="L1V38_002089"
     CDS             complement(16491..16652)
                     /locus_tag="L1V38_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316633.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5386 a         3102 c         3074 g         5105 t
ORIGIN      
        1 cgaaaaagta gaagttgggg gcacagtaga tctaacagat aatgttacta acttgccagc
       61 gttaccagaa ggaacaacag taacagatgt tactcccggc ggtacaattg ataccaacac
      121 accaggtaat tacgaaggtg tcattgaagt aacgtatcca gacggtacga aagatacggt
      181 gaaagttcca gtagaagtga cagacaatcg ttctgacgcc gataaatatg aaccaacagt
      241 agaaggcgaa aaagtagaaa ttggaggcac agtagattta acagataatg ttactaactt
      301 gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta caattgatac
      361 caacacacca ggcaattatg aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga
      421 tacggtgaaa gttccagtag aagtgacaga caatcgttct aatgcagata aatacaatcc
      481 tgaaggacaa aaagtgacta cagacttaaa taaagagcca gatgcatctg agggaattaa
      541 gaacaaagaa gatttaccaa aaggaactac ttatgcttgg aaagagaaag tagatgttag
      601 cacagctgga aataaaaaag gtactattgt agtgacatat ccagatggat catctgatga
      661 agttgaagta gacgttacag tgacagatac tcgttccgat gcagataaat ataatcctga
      721 aggacaaaaa gtgactacag acttaaataa agagccagat gcatctgagg gaattaagaa
      781 caaagaagat ctaccaaaag gaactactta tacttggaaa gaaaaagtag atgttagtac
      841 agctggaaac aaaaaaggta ctgtagtagt aacatatcca gatggatcta aagaagaagt
      901 agaagttact atttctgtag tagataaaaa agcaccgaat aaacctcaag ttgatcctat
      961 tacagagggt gaccaaattg ttactggtaa aactgaacca aatgcagagg tgacagttac
     1021 attaccagac ggaagtcaac accatgggac agctgataaa aatggtaatt ttacagttaa
     1081 agttcctaaa ttagaggcag ggacaaaagt gatagtaact gcaactgatg aatctggtaa
     1141 tactagtgaa cctactaatg tagttgtttc ttccaacaaa aaagacagtg gaaaaaacgg
     1201 tagtaaaggt agtaagactg acaatcaagg tagcaacagc aatcaagaca aaaatagagg
     1261 caaaagccag tcctcaaaag tttttcctaa gacgggagag agtgacagta atatctttac
     1321 tattagcggt ggtttaatac tgttaggaac gttaggatta ttagggtata aaaatcgaaa
     1381 aaaagagaat gaatagaaaa tcaatttctt aagtcttctc tgagaagagg aagaatcttt
     1441 ttcttcctct ttttgctttt ttatgatggg aaataagtgt tagttaaaga tgaatatact
     1501 ttttatagaa aggaaaagaa tgtaattaag tggaaaaaat agtaattatt ggttcaaacc
     1561 attcagggct agccgcagct cgatttctaa acttaagcga ttcaaattat gaagttattc
     1621 taatcgataa aaaatcagaa attagttact tggaatgtgg gacatcgtta tttataaaag
     1681 gagaagtaag taatttagaa gatctttttt atcaaaatag aatgacacta aattctgaga
     1741 taaaaaagtt atttctagag acagaagttg acaaaattga tattcaaaat aaaaagatta
     1801 gttgtgtaaa aaaagatggt acaagattct ctcaagaata tgacaaagtt atattagcta
     1861 caggttcaaa gcaaattatg ctagatatac cggggaataa tttagctaat attttttcga
     1921 taaagaattt tccaaatgca aaagagattt ttaaagcttt ggatgatagt actattaaaa
     1981 aagtaggaat tattggagca ggatatattg gagttgaaat tgctgaagcc ataagaaaaa
     2041 gagggaaaga agtatatctt ttcgatgttg cagatagagt gttgtcgact tattacgacc
     2101 gtagtttttc agataaagtt gaagaaatac tatcaaaaaa tggaatacat ctttgtctat
     2161 cagaaagtcc taaaaaatat ttaggaagaa aaaagattga aaaaatagtc actacaagtg
     2221 gtacccaata ctctatggat atggtcgtac aagctatagg atttctatct aatagtccaa
     2281 ttggggaaaa ggaactcttg agagatgtta gtggagcata tctaactaat gaataccagc
     2341 aaacaaatat aaaagatata tatgctattg gggattgtgc tacaactttt tttacgtcca
     2401 ttaatagaag tagtgttgat ttttctattt ctaatgctct aagaacagct tatattgcaa
     2461 ctcaacatat taacaatcaa gattttacac cttctggttc ccaatttaca aatggctttt
     2521 ctatatttaa ttacaatttt tacgcagcag gtttgaattt aaaaacagca cgattattaa
     2581 gtgagtctat agattatata gaaatagaag atttcattag acctgctttt ttgagaaaaa
     2641 atagtcgtgt aaaattaaga attagctttg aaaaaaatac aaagagaata gtaggtgtac
     2701 aactttgtag tcaagaagat ttatctggac tattatcaat gttttctctt gctatagaag
     2761 aacaaattac attagacaaa ttgaaaatgt tagattattt atttcatcct agttttagcc
     2821 aaccctataa ttttatttta aaggcagtaa caggattaaa cattgaaaca taatcgttac
     2881 taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt atcataattt
     2941 ttaatagaaa acactattaa agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa
     3001 aacttgcatc agcagttata ttaatgtccc aactccttat agcaacacct ttccatgtgt
     3061 tggcaagcga aaattcaaca tacaaaattg caaaagaaag aaccgagacg actgaaatga
     3121 gtaattccga tgtaacagca gagagtagtg aacttttgac aacttcatca agtgaaagta
     3181 gtacgacttc aaatgccgag tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa
     3241 atgccgagtc ttcaacaact tcgtcaagtg aaagtagtac gatttcaagt accgaatctt
     3301 caacaacttc aagtagtaca agtgaaataa cttcttcgaa agtgacaaaa ccaaaccata
     3361 tagaatcttc aaaaaaggaa gcgccaaaaa cggaaggaca aacaaaaact ttttcgacac
     3421 cacagcaaat agaatcaaca gaatctttcc aatcacaacc aatactatct ggtaatgaag
     3481 aaattcattt tgacaaaaat gaatctgtag aaaattttat tatgaaaatt ggtgagtctg
     3541 cgagaaaaat tggtcagaaa tatgatttat atgcttctgt tatgattgca caagcgatct
     3601 tagaatctgc cagtggtcaa agccagttag ctcaggcacc gaattacaat ttatttggga
     3661 taaaaggaac ttataatgga aactttgtca ttatggtaac aaacgaagat ttgggtaatg
     3721 gaacgcttta tacgacccaa tcaaaattta gagtgtatga aaactatgag gaaagctttg
     3781 aagattatgc caaattatta actaagggaa ttagtggaaa taaagatttt tatgcaggag
     3841 cattaaaagc taatagtaaa acatatcgag aagcaactaa attccttaca ggacggtatg
     3901 caacagatac acaatactat ttgaagctaa atgaattaat taaaacctac gatttaacca
     3961 actatgataa agaagttaaa ggtccacaaa tgagtaagac tggataccaa gtgcctattc
     4021 ataattattc aataaccagt ttgtttggaa atcgtggaaa tgaatttcac cgaggacttg
     4081 atatggcagc tacacagggt gagccgattc atgcagttaa agctggtaag gttgttaaag
     4141 cagagtttca ctactcttgg ggaaattacg tggtgataca acacgaagat ggatcaaccg
     4201 cgttatatgc tcaccagcaa caatacctag taaaaactgg agataatgtt ttgcaaggac
     4261 aaataattgg ctatgtagga agtactggga atagtactgg cccacacctt catttggaaa
     4321 tttgcaaaga tagtagtctt tctcagagca tgttagttga tccgaaaacc ttattattcg
     4381 gagactaaaa aaggtaatca atctgacaaa gtaacaagaa aatggttgga ttcttagacc
     4441 tttgatcagg atattgagac tggaattgat atctcgatta cgatgggttt gacaaataaa
     4501 acaagtccat tatcgaatat cgagtgtatt attgccgtct ttatgctcat attttgagca
     4561 ggtttcacta gatgaaaaca atttatctat cttgaggatt tcgtgtacgt atcgttcagt
     4621 cttgtattgt aaattagtca taaaatcaga ctaagaaaaa ttggaaatat ttttttctga
     4681 tttattaaaa gttaattgaa attatatggt acttctttct tgggagggta ggtgcagtga
     4741 aggaaagata tggtcacctt actgttgttg aggagattac tcataatgga tataaaaaat
     4801 atcgttgcct atgtgactgt gggaatgaaa cgattgtata tcgatcaaac ttactatcag
     4861 gtagaaccaa aagttgtgga tgtggaaatt ataaaaatag gcataaatat aaaaatttga
     4921 caaataaaac ttttggtaag ttagttgcaa tcaagccaac taaactgcga agtgaaggaa
     4981 ctgttgtttg ggaatgtcaa tgtctgtgtg ggagaaaaaa gttagtatcg gcaaagcgac
     5041 ttctaaaagg tgatgtaaaa agctgtggat gtttgaaatc aaaaaagcat cacattgaaa
     5101 ataaaaaatt cggattactt actgcaaagt atcctttgga caataactgt tcatggaaaa
     5161 caaaatgggt ttgtcattgt gagtgtggca gtatgtgtga gataagttat agtaacttat
     5221 tttttggaca tactcaaagt tgtggatgtt taaaaaggca agaaacaagg acatgtgttg
     5281 aagggacagt aatagagtgt ctaacgtcaa aattaccgaa aaataataca agtggtgtta
     5341 agggagttta tcgttctaaa gagaaataga ttgcgtatat aactttaaaa aaaaagaggt
     5401 actatttagg atcgtatgat tctattaaga gtgcagctca agctagaaaa gatgctgaaa
     5461 ataaattgtt tcaacctttg attgacaaat atcgaggtaa tcattaatta ttgtggataa
     5521 taattaacag tgatatataa acatctataa tatattattc atactattga tatttagtat
     5581 aatcctatgg aattgaatat catagcaatg tatttgaaaa gcaaattgga aaacaaatag
     5641 gtgcaacacc ataaatatga aaaaattggg aaaaagtaga atggaaattt gcttacgtct
     5701 cacgagatag ctcacactat taatctgaag aacaatgaag tcgactttta gaaattgcta
     5761 gaagaaagta aagcgaatta tcactagtta ctatagagta agttcaaata aagcatctcc
     5821 aacttacatg gttacatgag gatatcaaat cgaaattact caagcttcct atggctagag
     5881 tcgcgagaag ttgttgggca gtagacatag gttatattgt tcttagctac acgatcatta
     5941 gaaaggaaat cctattatgt atagttatca agaagatgca aaagtccaaa aaaatcgctg
     6001 gtggattttg attgctatat ctatgtttac cttcatgtcc acattggatg gcagtattgt
     6061 caatattgca ctacctacca tctcagatga tatgggcata ccaatgaatc aagcggaatg
     6121 ggtagtgtcc gtttatctga tgattgtctg ttcttgtttg ttgctgtttg gtaaaattgg
     6181 cgatagccgt gggaaaatca aagtatttcg gattggtacg ctgatctttg tcttgggatc
     6241 gctgttgtgt gggttcaatc attcgctagg tattttattg ttcgcacggg tggtacaagc
     6301 cattggtgct agtatgacta tggctacaaa tgccggaatc atcacggaag tctttcccat
     6361 acatgaacgt ggtcgggcat tgggagcaat aggtgcgttt gtttcattag gctcgattgc
     6421 tggaccaggt cttggcggct tgattttgtc ccaattttct tgggcgtaca ttttttggat
     6481 caatgtaccg gtgggaatcg taacgatgtt gattgctgaa aaattcttac caaaagatat
     6541 caccatgagc ggccatacaa tcgatggagg gggctttgct gccattgcgg ctacgattat
     6601 cagctttttt ggagcaatct ttttggggca agaaagtggc tttttccatc cagtccccct
     6661 tgtactgttc gtaatttcag tgattgcctt tgtcagcttt ttaaaagttg aaaagaaagc
     6721 agcctctcca ttgatttctt tcggtatttt taagaacaag atttttacca tgagcttgat
     6781 tacagccttg ttgatttttt cttccaactt ctttgtcaat gtagtgattc ctttttatct
     6841 gcaaaatgct cgcgggttga gtcctagcta tgctgggctg ttgatgatgg tctttccttt
     6901 gatgatggtc gtcggggcgc ctttaagcgg ctacctgacc gaccgggttg gcccggagat
     6961 tttggtatta gtaggcttgg gcttattgtc ggtaacccag gtcatgtata tgtttttgtc
     7021 agtggactct cctttgtggc tatacattgt cgctactgcc atcatgggtg ccggcaatgc
     7081 cttgttccag tcccccaata atacgatggt tatgagctcg gtcactatcg aaaacttggg
     7141 actggcaggc tcgatgaatt cctttgcccg aaatttgggg atggtcagcg ggatttcgct
     7201 ttctacgacg gtcttatatc aagcgatgtc tgctaagatg ggccagcaag taactaacta
     7261 tatcgcaaat cggccggatg tctttttata tggaatgaag attacctttt taggcagctt
     7321 tgttttgtgt tttgttgcct ttttcctgac tatctggcgt atcaaaaaac aaggaggtat
     7381 tcagaaaaat gtctgaaaaa accactgttg aagaattttt ggaggcctgc gtatgggtga
     7441 gtgggatttc catggatgat ggaagatgaa gtgaacttct aaaagccgaa aaactcaagt
     7501 attatcttca aaatactagt gctcaatgag atgcttgatt tgatcacaag aagactgcga
     7561 aagccgctgg caaccgcaag ctaggtatcc caccgatgga ctacgtttta gaggctactg
     7621 gttatgaata cggagccaac gctctcatct gcataagaat acatcaccca gattatgtaa
     7681 agattttcga tacttctgtc aaaaaatcat taagatagat aaatgatttc cgtctagtca
     7741 aattggttca gaatgtagac acacagatgg taagaagtca ctcacaattc gagaatggac
     7801 ttgtcctatt tgccgtatac atcataatcg aaacgtcaac gatagtatca atattttgac
     7861 caagggctat gaatacaagc attgccttag aaaacatcaa gaaccttagg aacaacgggg
     7921 atagcttggt taataagaga taccgctgtt taggcttgca agtatactct tttatcaaga
     7981 attccgtggc tttagtcatg agaggcttaa tactatgaaa attttcttta gcatttttga
     8041 tttaggttcc ttttctaatt ataataagat gaccactaca gtaacctact gaaatatata
     8101 aacagccact gtagtaccat tttcaaagta gtctatgaga ggagaatctt cattcttatg
     8161 aacgctggaa ttgcggatat gaatttaata aaaaaaaccc ttaatgattt tacttccaat
     8221 tcaatatcaa aaggtactgg tatcaattta agcacaataa aaaagctgaa aagtggtgaa
     8281 agatcagtgg aaaagctgaa tcttttagat gctataaaaa taacggaatt tgctatgaaa
     8341 aatggaaaag ctgagattga aatatggaga taattatcgt ctagtgaatt acttgccact
     8401 tagctgaatt taacgatcct tggtgcttga agggggagat tcttgggaat agagcatact
     8461 tgcaagccta tgtctttact aacaacgata tctcttatta accaagctat ccccgtagtt
     8521 ctaaggcttt tacttttatc taagcaataa tcgtattcaa aggaaatttt tgacccttag
     8581 aaagtctcat tttatcagac gtgagcttag gcattgctga attttgttaa ttcggtttta
     8641 ggttgtgctt tgagcataat atgaaagtat tctttatcac gatttcattc atctaaggta
     8701 atgtgatgtg attctgaaat tctttcaaag gcagtttttg cataagctga cattacatca
     8761 tcaatgacat gtttacaatg tttcactact aaaataaggg ggtaaccaag aagaaaaact
     8821 gaatgattat ttgtatctaa ttccatggta tatcaaccat ttcctatata gactgattat
     8881 gacatggatt aaaataaaaa ggcactatgt cttaattgtc ggttttcgag ttaccgaatg
     8941 gcattcatca cccacctata gaggatgggc gacttctgcc tgaaataagt tacactactt
     9001 ataacttcta ataaaattag attgagtcat tattatttaa catcaacgat tttccagttt
     9061 ccattttttt gtaatactaa tttgtactga aagtagctag tggtttttga tacattatca
     9121 aggtatttta tctttgtact cactagaaaa ttttttccgt tttgtagata aactggattc
     9181 tctaactccg aaaactttaa gtcaatattg attggtcgca tcgcaccatt ttcaacataa
     9241 tactccaatt ctttttcaga agctgatgga taaagtttaa aaaatgtttc taaaaaatcg
     9301 gtgatttctt ccgttgtttt ggcatcaatt tctgaatcgt tttctacttg ttttgcttca
     9361 tattttgcct tgtctggctt tccaatcatt gttggcaaac tagttactaa atgattcctg
     9421 ttttcatctt caaagattgt cactcgatat gcagaagaaa ttgattgcgt cttttttccc
     9481 tctgtaatat gttgctccac taaaaatgaa acgacaaatt cttccgagtg tttttcaaca
     9541 tctagaattt ttacagattg aacttcggaa ctcgtgggaa tatctgctcg aaccatatct
     9601 tggattaaag cgagaccgtt ttctgtaagg tactgttcga gattactcat tctcttttca
     9661 attgcttctt tgttattttt ccatgaaaaa tattctttcg caaaatcctc tgtaaaactt
     9721 tcaacgccag aagtattcac taccttctct tttataacca ctttttcatg agttgtatgt
     9781 tgatcaatgg cggtgaaatt tttataaacg ccaaaagcaa gactacaaga caataaaagc
     9841 caaagggcaa gcaccatttt tcgatgctta cccacggata caactcgttc ttttttcttt
     9901 tttgggctct tttccttttg attccgttca atttttatct tcattctttt tcctcttttc
     9961 tcttatttgt atcggccagc tccgataaga tgctgccgcc aatagttttc cgttagattc
    10021 gtccacccca ctggatctcc tgcatgaaac atgcgattct cccctgcgta aatgcccaca
    10081 tgggtcacat aagtaccggc atcataggtt gaatgaaaga aaactaaatc acctggtttg
    10141 gcatctttta gatcaatatg agtcatggca tcatattgat cctgagccac ccgaggaagt
    10201 ttcaggtcaa ctttggcata acaccattgg gtcaagccac tacaatcaaa ccccgtttct
    10261 ggacttgagc caccaaacac ataggccgtt ccttcatact taaatgcctc atcaaaaatt
    10321 tcttggacta ttttgtcatc aaactgagtt gtagttaggt attgcttcac taataaacag
    10381 taaaacatat tgccataatt ataccgccac ccaccatttt ccttaatcgc gattgggttg
    10441 gggtaatcga ctttttgacc acctgatttt tcctttgaaa aagattcagc taaagcaaaa
    10501 ctatgcttct tcccgttttt cccgacatga tctagatacc cgccaccata gttataggcc
    10561 tgaataatac tatcttgatc acaccctagt tctttggaac gcttaaccaa agacgcaaaa
    10621 tagagacagc cttgtttgat ggatgcctcg gtacttaatg aattaggtgg taatccggct
    10681 gactcagaac tttgcataac gtcttccatt gtgccaccag attccacttg aataatcgcc
    10741 aaaagaattg gaatatactc tgttatatcc gattctttgg catacttttc caccattgca
    10801 cggtgtttca atacttcttc tgagacacta gttccgccag gagaagtgcc agaactacca
    10861 tttccctcac tgtcttcacc aaacaacaaa cccacacaca tcaaaatacc cataaaagag
    10921 atggtcagaa aagttaatga aataacaccc actttcttca agttcatttt ttctcacctg
    10981 accttgattt tggacgatgg ttcattcttt tttgtacttt ttgattggtc tgctttggca
    11041 gagtggacct ctgtttcact tgttggaaag aatttttctt acttgctgat tggcttttcc
    11101 cttttgaaat gatttcttga ctagttagtt ttcgtttgat ttcgggattc agatttgctc
    11161 tcacaatccg ctttggtgct tcttttttca gcatcatatc tttctgaggt tgagctgctt
    11221 tatctattgg aatattcgcc cttctttttc cctgacgatt tgttgcttca ctcagtatct
    11281 tgcgtttttc gtccattttc gcatttcttc gttgtcgttg tttttctcgc aaatccactc
    11341 gatccgcttt ttcttggaac agtccgcgct tgaattcttc tggtgctttt ttcgactttt
    11401 cgattccttt atggagattg tatttcaaat tcgttggcgt attccttacc tgatccttta
    11461 cttgtttagt cttatctttc accaaagctt gggtatccaa aactttgccg atttttctcc
    11521 cagccaaatt cattcgggat tgtttcttat tatttgaaac tggattctcc ttagttaagt
    11581 cagatagtat ttcgtgatcg ttcggtaatc gtgaattctt tcgtagagaa gaaccggatg
    11641 gcttaaattt ggattttgat tgttcctttg ccaacttatt tccgactgct gcaccaccac
    11701 caaaagccaa agctcgtccc acatttcgat tgagttgccg caattttcga ttcattaaca
    11761 tttgcggttt tcgcatgacg cgtcttccca ttgactggct atcattactc tggaggttga
    11821 acatactcat aatgtcgccc aatttgaaat agataccggc aaaggtcaca atttgcagaa
    11881 aagcaaccat gaaaaatgga taggttgccg aaatattgaa aaacatcgtg gagatgctaa
    11941 atgcagtcgt aatcaccaaa gtaacacccg ctcgcatcat aatcgtattg aataaacgaa
    12001 taatcgcctt ctttcctaaa ctttcataag tcggcaacat ggacaataag aaactaattg
    12061 gcagaaacat cgcaaagata atgaagagaa tttgcgagaa caacataatc cctgttagaa
    12121 gaaaaacaaa gaaggaaatg ccaatattga acaataccaa aaagaccacg gtccctaaac
    12181 ggttcatggt cttggtaata ctgagattcg cattgtcatt gtcttcaatc tctgccttga
    12241 ccgcttcttc ccgatctttg cctttgtttt catctggact cacagataga atcttgttga
    12301 cccggtcttc accaatttct tctatgttgg aatcatcaaa ttgcagtagt aaccaaggtt
    12361 gttggacttg aatcgaaaac aaactatccc gaatcaaatc cacactatct tttccttggc
    12421 tttctgaatt gggtacaacg atctcggttc caagggtaag ggccgcttca ctaacatctg
    12481 agctaaagtc attgattttt gtgatatagg taggcgcata agcaatgaac gaacccgata
    12541 gtagaaaaat catcacaaaa ttaatcacgg ctcgaactgc tttcgtggtt tctcgtttta
    12601 ataatccggt atacgccaca tacaccccca gagctaaaat catcaataat agaaacccaa
    12661 aataaaatcc ggaggtctgg agtccatttt cagtaatacc agccaatgtt tggatattct
    12721 ttccaatact ttcagccgta tccgaaatga aatctaattt gtaagcctct tgaaccacat
    12781 aacccgtggc gttcgacaaa tacaaactca ccgtccaaat gaaattagta atggcataaa
    12841 gaccatacat cacgcttttc cctaagccat caccccaatt ccaaggcaac caatcccaag
    12901 agctatccac aaagaaatct agttgatagt tgttcagtga atatttggaa tatagatttc
    12961 ctgcttcaac tgtatcatca actagccctg tcgcctcggc taccgtacca actaaactca
    13021 atagaactat cagagtgagt atgctaataa aaacgattcc cacaatccga aaaagtttct
    13081 ttttcatccc ctcactccat tctctcttga acaggtggac gggtatcaaa ggcatggaag
    13141 agttcttcaa agactggatg tacctgaacc acgcctaccc gaccatacaa atcctgcatc
    13201 aagcattggc cattttccaa atctcgtagg cgtttttgat tgctttcatc ttctcgatcc
    13261 aagccaaaga attccaaggt tttcttgatt tcatgaatat cggtactgcg aaacgcaaac
    13321 ttcaacccga tattattctt caagcgttca tccagtaaat catcactatt ttgcgtgaca
    13381 aagtaaaccc cggcattcat agcccgccca gcacgaacga gcttattcga taatgttttc
    13441 ccttgcgcta cttgaagaaa actccacgcc tcatctaagt ctacaatttt gaagatttct
    13501 cgattactat ggataaagtc caaggcaaaa gtggaaatga cgattagcat ggaaacacta
    13561 agcaattcca tggtggtata ttcttcaaaa gtggtttctg catctggtaa aaccaaatcc
    13621 gctacttgaa tgatatttaa ctgcctatct aaactaatcg actgggtaat cgaaccatct
    13681 gagaaaagca aatgggcaaa atcataatcg gtaaaggact cgatgtgatc cgcgatattt
    13741 tccgcaactg gtgagccttc ttttcgaagc tcattaatta cttgtaataa tccccgttga
    13801 ttgctttggg taaccgtccg aatggcctta cgcaacactg gaaacttctc cccatctcga
    13861 ctagaaattc ctgttaaaaa ggtcagaata tcaattgcta gactttcaga atccttcttt
    13921 ttctccataa tcacataagg atcaagtaat ccttgatttt ttggcttact agttaagttg
    13981 agaatattga tttcatccgc aatttctggc aaggtttctt tccagccacc ccgttcccct
    14041 tttggatcga caatcacagc ttgtccacca aaaaggacgg cgtaataaac taagagattg
    14101 ttactaaagg actttccgcc accgagtgaa ccgaggaatg ccgctgctag cgcattggta
    14161 actgaatcct tgaccccttg tgaggccaat gccggtttca ggtaaacatt gcgccccgta
    14221 tctacgttat aaccaaagta aatgccttcc aactccccta acatctgagt ggcgccaaaa
    14281 ccaagtccgg cgagaaaatc agacgtaaca tactggatat aatcattcat gtatcgctta
    14341 ctagaaggta agaattcttc atgtagcccc atcatatcgc caaaaggccg gactagtttt
    14401 acattggtat catcataaaa atctagcact tcatcacacc ggcgctttag ttcatctact
    14461 gattcggcac ttactcgaac cacatagctc agtttgtaca tggattcttt ggactgatcc
    14521 aaggtagttt ccaattcatc tacggaatcc aatgcatcta agacattgga atttgtttca
    14581 ttgtcagatt gataggcatg gttgtccaag tcttttaatt cctttttctt attgcgaacg
    14641 gtagcaagtg cctttttgtt cgtcacaatc tccacattca tactagtgtc aattgggaat
    14701 gtaaattgtt gttgctggta atagaaaagt tctgaggagg gaaactccat ttcccccaca
    14761 attgtattaa ttgttaagta cgctacatat gattcatgat tctcatgttc catgcataag
    14821 taccggggct tttcttcaat caaacaacga ctgggacgta ataagtcgta acgtttcacc
    14881 aaagtttccg acttcagctt tttctttggt agctgaaatt catattcttc aaatggtgta
    14941 cccttttcgc catagatatg ttcaatcaaa tacatcagat cactcggtgt gactcgtctg
    15001 actttaaatc ttcgagccaa tttactttcc attagttttt caagcttggt atatcggcga
    15061 atttcttcat tggataagga aacaaaatcg cccatcaaat gatgattcac tccatagaca
    15121 aattcttgaa agccggagaa gaaagatttc ttgagattct ttagattgac ctcttcatct
    15181 gtcgcaatca gtttgaagcc aataaaaaag cgataatcaa tctgactatc gccaatcatg
    15241 gatactaatg cctctgtctg taaatcaatt cgttgtttcg ctacttctgt taatcgcccg
    15301 gtaatttcct tttttgatcg ttcttgcgtg gcacgaatac tactttctgt ggcaatttgt
    15361 aaggcatgaa tcttgccttc acgattttgc gcaatcaatt gacgaaagtt atcgtggact
    15421 tgatatttct gttcaggtga caaaaaggag taattgtaag gtattaactc atagtaggca
    15481 aaacattctc cctcttgatt aaagacaaga ttattttcaa tatacttaat cgggtacata
    15541 gttcacactc cttaccagag taatgggttc gtcccatcgt ttcttctgtt ctttgacttt
    15601 ctttcctgcg aaagtgacct taaatcgtaa gtgatagcta ataaaagatc gtaaaaatcc
    15661 caatggtttc ttaccgtcaa acgttttttg cgacatgaac caagtaactg ccaccggtat
    15721 acctaagtat tttaaaaagg ccccctctat catagatagt ggaggcacat gggcaaatac
    15781 gatgacaaac agcaaggata aaacaaacca agccatctgg ttaaaagtca caggaaaagg
    15841 cagttgaaag tcattaattg cataaatgac cttttcaact gcccaaatac tggtgtagct
    15901 ttttattttc ttcatcaaat cattccttta aaaagaagga tagtttagaa atcaactacc
    15961 cttcaataat tttgttaata tggatactca aaaacacctc gactcgttac caaataattg
    16021 cctccaatct ccaagtctct accacacgca tcaaaatcaa tatacgtctt caagtgttct
    16081 ggtacttctc caaaatcacc agcttctaca atcaagaaat atgctacatc actcatatca
    16141 tcgcaatctg gataatagat aatatcatcc acatgctcta ccatctcctc aaaagaattg
    16201 aagaaagcat gttgaatctc agaagcaact tcaccaactg gcgttccttc aagttcctcc
    16261 gctaagccac acaaccgatt aatttcctca attggcgtat actcatcaat ctcaaaggga
    16321 agttcataat catgaattgc atattcctcg tattcgtcat ttaacccaat tcgttctttc
    16381 acttcatcaa aatcgacagg tggggtaaac cacgccccca ccaattcacc ttcgttatat
    16441 ttcccgaggt tcgcaatata aacacgcatc tgttccatcg tgcttccccc ttacgcaccg
    16501 acaattcggt taaacaaact gagtaagaca tccttcaccc cagaagcatt aaagaccaat
    16561 ccgaccgcaa tcaaagcaat caccaaaaag ccaatcagtt tggaaaactc ccgcttaaat
    16621 cctaaaaaca aaccaatgac cacaattgcc agtaagacta aggattg
//
LOCUS       DAFLWZ010000061        16317 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000061 DAFLWZ010000000
VERSION     DAFLWZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.061"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..477
                     /gene="scm"
                     /locus_tag="L1V38_002090"
     CDS             <1..477
                     /gene="scm"
                     /locus_tag="L1V38_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1316634.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(632..1618)
                     /locus_tag="L1V38_002091"
     CDS             complement(632..1618)
                     /locus_tag="L1V38_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1316635.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1641..2207)
                     /locus_tag="L1V38_002092"
     CDS             complement(1641..2207)
                     /locus_tag="L1V38_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBN1316636.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2221..2637)
                     /locus_tag="L1V38_002093"
     CDS             complement(2221..2637)
                     /locus_tag="L1V38_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1316637.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3094..5028)
                     /locus_tag="L1V38_002094"
     CDS             complement(3094..5028)
                     /locus_tag="L1V38_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1316638.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5309..6265
                     /locus_tag="L1V38_002095"
     CDS             5309..6265
                     /locus_tag="L1V38_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBN1316639.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6355..7458
                     /locus_tag="L1V38_002096"
     CDS             6355..7458
                     /locus_tag="L1V38_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBN1316640.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7471..8424
                     /gene="menA"
                     /locus_tag="L1V38_002097"
     CDS             7471..8424
                     /gene="menA"
                     /locus_tag="L1V38_002097"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBN1316641.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9238..10584)
                     /gene="gor"
                     /locus_tag="L1V38_002098"
     CDS             complement(9238..10584)
                     /gene="gor"
                     /locus_tag="L1V38_002098"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBN1316642.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10718..11971)
                     /locus_tag="L1V38_002099"
     CDS             complement(10718..11971)
                     /locus_tag="L1V38_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1316643.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11977..12900)
                     /locus_tag="L1V38_002100"
     CDS             complement(11977..12900)
                     /locus_tag="L1V38_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1316644.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13121..15613)
                     /locus_tag="L1V38_002101"
     CDS             complement(13121..15613)
                     /locus_tag="L1V38_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1316645.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15620..16087)
                     /locus_tag="L1V38_002102"
     CDS             complement(15620..16087)
                     /locus_tag="L1V38_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBN1316646.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16223..16296)
                     /locus_tag="L1V38_002103"
     tRNA            complement(16223..16296)
                     /locus_tag="L1V38_002103"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16260..16262),aa:Arg,seq:acg)
BASE COUNT         4796 a         3418 c         2905 g         5198 t
ORIGIN      
        1 agcacggaca cgtcagcttc aagcgacagt acggatacat ctaccacaac aagtgatagc
       61 acggacacgt cagcttcaag tgacagtaca gatactacct ctaccacaag tgatagctca
      121 gattcatcta ccactacaag tgatagcacg gacacgtcag cttcaagtga cagtacagat
      181 acatcctcta ccacaagtga tagctcagat tcatcaactt caagcgatag tacagacacg
      241 tcgtctacca caagcgatac acgtcatgca agtgtctcct tctcaaaaac aagttcggat
      301 aacaggacga actttaactt aactaataaa acaagcaatg acaatggaaa caaatcaaaa
      361 agagcacttc ctaaaactgg aagtcaatcg aataattgga taacactcgc aggcgttata
      421 ttacttgtaa tcggtttaag aatcactttt atgagttata agaaatcgaa aaggtaaaaa
      481 aatattcaag ataaaaaaga gcaacgtcgc taacggacgt tgctctttat ttttgctttt
      541 tatcataaat acaagaacta caattcaatt tgtcaaaaaa cacgtagatt tccttctgag
      601 aaatttattt acgtatcgaa cctttcccta ttcagtcttt gcgatccaaa atcagttggg
      661 taagggaaaa gagattctct tttgttcgaa gagaggtggc aggtaatttc tttatttcct
      721 tcaaagcctt ttctgtgtaa gaggccgcta acttcctagc ttcttccacg cctcctgtat
      781 gttcaacgat tttgcgtacg gcgtcgacat cttcttctgt cattgccgct ttcttctcta
      841 aataaggtag tagctttggt ttgttttttt gcaaagagta gatcaacggt aaagaataga
      901 ccccttgacg catgtcttct agtacaggtt tgccgatttc ctggctctct tttgtataat
      961 ctaaaatatc atcgataatc tgaaaggcca tcccgataga aagtccgata tctcctgctt
     1021 tttttgcgaa gcgctcgctt gttccacttt caaaagcgcc aacagaacaa cttaattgga
     1081 acagttcagc tgtcttacct gaaatatttt ccaaatattc ttttacagaa agttcataat
     1141 tatagcgatc atccatctgc cctaattcgc cattcaatac tttttccata ctgcgagaat
     1201 tcaattggag acttttcaag gaagtggagt aatcagacaa tagtttaaaa cagcagacaa
     1261 ataaatagtc tcctgcatag acagaaacga cattaccaaa ctgactacgg atattaggct
     1321 gaccacgtcg cagatccgct tcatcaacga tatcatcatg gatcagtgtg gccgtatgga
     1381 gcatttcgat agaagctgcc aaagcgatgg ctttgtctcg atcttgctct ggtccaaatt
     1441 gtgagaacaa tagctgatag gcaggacgca acagctttcc gccggcatgg atcgtttctt
     1501 tgattgcttg ttcgacaggt ttgtttttca ggcggacagt ttcttccatc cgttttagtg
     1561 tttctgtcaa ttctttactt aaagcaggat agttttccca cattggatgt agcttcataa
     1621 aaaaactcct tgtgtgacga ttattttttg gtaaacattg ggctccattt ttgtttggtt
     1681 ccctgctcat aatctttttg gaatcgttga agtgtctgca catgtcgtaa aagataattc
     1741 gctgcgatcc cgattgcaat ccctgataaa atccctaaaa ctgaaaggac tggcaagtac
     1801 aacatgactg tccatgattg tgcaatgaaa gaagccatca aaagctgtcc gacattatgc
     1861 atgaaaccgc cggccgcact aattccgatg atactgacac gttttggtcc taattgcttg
     1921 accaataaca ttccaaaata actaagcaaa gcaccactca tactataaag gaatgtggaa
     1981 atcgttccgc ctagcaaagt agtcaggaat agtcgtagcc aaagtagtaa gaagctgtct
     2041 cgttttttca tggtaaaaat ggcaacgatc gtgattagat tggctaagcc tagttttgca
     2101 ccaggcgcaa aagaaaaagg ataagggatc atattttcca ataaaccaat gatcactcct
     2161 tgtgcaacaa gtagcgaaat ataaatcatt ttttgtaatt tactcatggt gtgtgaaggt
     2221 ctaataaatc agactgtctt cgtcacctcc atctgttgaa cggacttcga tcactaattt
     2281 atgtggcaaa cagacgatgg tttcgccatt tttcgttgcc cagcctcgac gtacgcagat
     2341 ctggtcatcg caatctgctt cttttatccg tactcgatcg ccatctatct cgatcaagtt
     2401 ataatctccg tgttcatctt tgtaagtata tgtgttgctc tcttctccag ccatcaaagg
     2461 gaatgttttg atttctgtgc catccacacg cagtaccgct tctttttctg ctgttgcggt
     2521 gttttgctga agaccaaaaa tcatgactgg taaaaaagaa agaacagtca aaagcaaaat
     2581 aataaaaaca tcccaaggtt tgagcagact tttttcagca aattctttaa ggctcatttt
     2641 tgttctcctt tttccagatt aactcaccca attttagcat aaaaacaaga ggttgtgaca
     2701 cctgtgtctt gctttgagta ataagaacga agaatagaaa acagctttcc atgttttcta
     2761 attctttggg cttattaccg agaagcagca ggtggaacac cgtttataac aagaggttgt
     2821 gacagaagtg ggcaacttca agaaataaga aggaatttac gaaaattact tttcaagttt
     2881 ttgtgaaatt tcggcttatt tttcgaagaa gctacttctg gaacaccgtt tataacaaga
     2941 ggttgtaaca gaggttgtga cacctgtgtc ttgctcatgg aggcttatct cgggcatctt
     3001 attcctttaa ttttacataa aaaggaggct gtgacggttt gtctcagccc ctttctattg
     3061 aaatcttgca ttcaaataac gttctttatc tatttatttc ttgccgtact gggaacttgg
     3121 tctaccgtac caccaattac ctagtgtacg ttgtagccat ggaattaccc agcgatccaa
     3181 cccaatcgca cgtccggaac cgttcatcaa tgcgaaagca acaaaaatga accaaatgtt
     3241 tacccagtaa aacatgcctg ataagcagaa cgtgatcacc aatacaatcg ttgtcgcact
     3301 gcatagccat gtgaataatc cagcaatcaa tgctaatgcc aaggcaattt caaagaatac
     3361 catgaatttt tggaagaaca ttgctacatc attgtttggc atgatcactt gcatgatctt
     3421 tgtgaaccag tctggtgact tctcaatcac agccattggt tcttcaccgt atgcataact
     3481 caaaccaaaa tgtgcagctt gagtcgctgc ttctccggca cttgcccctg ctccgctggc
     3541 agctgtggtt gcatcaccag cagcagaagc accactggca acatctgtta cattgtattc
     3601 ccatgtccaa gggaacacac tgtttccagt gaaccatgat ccttcaccaa accaagtact
     3661 tggtttgaac acttcaccat tcccaatgat ttttttggaa gcttcaacga accaaactaa
     3721 accatagaaa atacgaagtg gcacactcca taagacattg ccgtaacgag aagaatgtcc
     3781 tcgagtcacg ttgcgatcat ctttgatatg gaaaaactca tgcattaaat attggaacat
     3841 ataataacca gaacgaatat caaagaagta tttcaaattc acgatatgtt tcattacgat
     3901 agctaaaaat ccgcttaaat ggatcttatc aaataggtta gctacccccc atttggcacc
     3961 aatagaaacc ataaatcctt gatagtttcc tttaaattta tgcttttctc cgcctttgat
     4021 cgaagccacg atattcgctg cggctgtgtg tcctgtttgt tcagcagctt gaacgatctg
     4081 cggtgtcggt gttcctggga attcttcata aaagactaaa tcaccaatga tatagatgtt
     4141 tttatcttcg tagccttttg cctgcatata ttcattggcg atcaaccgct gtccgcgtgc
     4201 tgattctaat ccaaagtcag cagcgtcaga agttcctttg acaccagctg tccaaatcag
     4261 tgtgtgagtc ggaatgttgc gtccgtcttt caatttgata tgatcagcag ccacttctac
     4321 gattggtgca ttcaataata attccacgtt gtgcttacgc aaatagcgtt cagcttttgc
     4381 agcatcattt cgatccaaca tattcaagat cgtcggcatt gcctctacga ccatcagtgt
     4441 gatttcgttt ggatctaatt tataatcttt ggctaggcga tttttccagt cgatcagttc
     4501 cccaatcatt tcaataccgg taaatccaga accacagaca acgaaagtca gcatggcttt
     4561 acgcagttca tcatctggtt ccaatgcagc ttttgctact gtcttctcaa tatgttcccg
     4621 aatccttaca gaatcttcaa atgaccaaag ggtgaatccg tgtgctttga caccaggtgt
     4681 accaaagtca ttcggctctc cgcccattcc aaggatcagc tgatcaaaag gataggaacc
     4741 taatttggtc ttgacgattt ttcgttcttt atcgataccg attacagtgt ctgtgacaag
     4801 ttgtacattc ttttgacgag caaacaaatg ctgcagatcg tattggattg cttctggttc
     4861 tacacgtccg ccagctactt catgcaactc ggtcatcata gtatggtacg aatgacgatc
     4921 gatcagagta attgctacat cttctttttt cagtttcttt gccaagtatt ttgtagctga
     4981 aacaccggca tatcctgctc ctacaacgac aatattttgc tttgccattg atcatccgct
     5041 ccttatagac tatctatata atgaatatat gataattctt ttagtttgat acttattaca
     5101 caatctccat atattatata gatgttctgt tcttttgtct aactcctttt ggattttttt
     5161 caaattttaa aataaagcgt tttttcacga aatttgctga aagaaaacgt ttgaaatatt
     5221 acatgggtta tttatcaaaa atagttgact tataggctaa aaagattaga atgtataatg
     5281 aatcacaaag aaaaattgtg gactagaaat ggaatggtgg ggtattaaaa tgaagaaaaa
     5341 acgttttgta actggatttg ccgtattagc attttcagct ctagtgttag gcgcttgcgg
     5401 cgcagatgac aacggaagct caaactcttc ttctgaatca tctacagcac aatcttcgac
     5461 tgcaaaaagc acaacagaat catctgcaaa agttgtagct ggcggagatt tgcaagacgg
     5521 cacatataaa ttagaagaaa aaaattattc aaatggttac cgtgcagtct ttgaaatggt
     5581 tgtaaaagac ggcaaaatca ctgaatcaaa atatgataac gtcaatgaaa acggcgaatc
     5641 aaaaacaaaa gatgcagaat acaacaaaaa catggaagca aaatctggca caaacccaga
     5701 aaaatacatt cctgagttga atgaccaatt cttaaaagca caaagcgcaa gcggtgtgga
     5761 agtcgtaact ggagctactc actcatctga aagcttccaa aactacgcac aacaattgat
     5821 ccaagctgct caagctggta acacagatac aatcgaaatc gacaatggtg ctgatttgaa
     5881 agacggcact tacaagcttg aagaaaagaa ctactctaac ggctaccgtg tgcaattcga
     5941 aatgacagtt gctggcggca aagtaactga atcaaacttt gattatatcg acaaagacgg
     6001 taaatcaaaa caagatgata cagaatataa tgaaaatatg aaagcaaaaa gcggtacaga
     6061 accaaaaact tacatcccta ctctgaacga cgaattcgtc aaagcaatgg gcgaagaaga
     6121 tggctcacct gctaatgtag aagttgttac aggtgctaca cacagctcac attcattcat
     6181 catgtacgca caacaattag tgaatgcagc tgaaaaaggc gacactcaaa caatcgaagt
     6241 agataatatc gtaacagaaa aataatcaca taatcatact aataaaagtt ggagggtggg
     6301 acgatagcca gattaggcag tcgtctcacc tttcaaaatg aagagaggaa aaagatgcgg
     6361 aaaaaactac tattttcctt aatcacactg ggcatctctt ttatggtgct aactggctgc
     6421 agcaactcag caaataaaac aaccactgaa agttcagcag ctaccaagat attgaaagat
     6481 ccatattctg atgaacagtt cttgttaggg acttacgttc gtatccgtgt gtatgatgaa
     6541 ggcaaagaat cagcattgaa acctgccttc gatcgagtaa aagaacttgg tgataaaatc
     6601 acgatcaatc aaaaaggttc tgagatcgat gaagtgaatg agcaagctgg gatcaaacca
     6661 gtaaaagttt ctgatgacgt ctacacgtta gtcaagcggg cctacgaata tagccaagat
     6721 tctcaaggcg gattcgatat ggcgattggt gcaatcacac aattatggcg aatcggtttt
     6781 gatgacgcca gaaaaccttc ccaagaagaa atcgatcagg cattgaaatt agtggattat
     6841 cataagatcg aactaaatga caaagaaaaa actgtttatc taaaagaaaa aggaatgatc
     6901 atcgatttag gtgcaatcgc caaaggttac attacggacg aagtagtgaa agtcttgaaa
     6961 aaacaaggag tgaccactgc catcgttgac ttgggcggta atgtctatgt cttaggccac
     7021 agcccaagag gcgaaaacca agactggaca gtcggcatcc aagatccgaa catggctcgc
     7081 ggatctgttt taggttctat taaagaacgg aacaaaacat tagttacctc tggaatttac
     7141 gagcgttatt tagaagtaga tggcaaaaaa taccatcatt tgtttgatcc aaaaacgggt
     7201 tatccgttcg acaatgatat cgcaagtgtc acgatcataa cagataaatc aattgatggt
     7261 gacgggttgt ctacagcagt cttttcaatg ggtgtgaaaa aaggactgga atacgtcgaa
     7321 agcgaattga ataacgggac ggaagcgatc ttcgtgacaa aagacgataa agtatatgtg
     7381 accgatccaa tcaaagacac cttcaaatta tcggaggact cccattacac gatgggtgac
     7441 cgttctgaac taaaataagg agtacgaacc atgacactaa aaatcttttt agaagtagtt
     7501 gaaatacgaa caaaggtggc tagtgtattt ccttttgcgg taggggtatt attctctatc
     7561 gctttttttc atgagataca ttggctaaac acttttttat tttttattgg aatgctagtt
     7621 tttgatttag cgactaccgc tatcaataat tacatggatt atgaaaaggc tcattctgaa
     7681 gtatataagt atgaagaaaa tgtcattggc cgcagaaatc tatctcctgt attgattcga
     7741 aacatgattt tagctatgat tgcatttgtt tttgttatcg gcgttattct aacgatcaat
     7801 acgggttggc ttttactttt gatgggattt atctgttgtt ttattggagt attctataca
     7861 ttcggaccga ttcctttatc tcgaatgcct ttaggggaaa ttttcagtgg ggtgactatg
     7921 ggccttggaa tttttgccat ggtcgtttat gtcaatacat tcggttcaga tgtctatgat
     7981 ctgacagtca acttttcatc tggacaattt gctttggtag gaaatctttg ggctatagca
     8041 gcaatcgtat tagcttcctt acccttggtg tttacgattg ccaatatcat gttggctaat
     8101 aatttgcggg atcttgaccg tgatattgaa aatcatcgct atacactagt tttttatatc
     8161 ggacgtcctg cgggaacagt cttattccag ctattgatgt atgcttgcta tttcgtgatt
     8221 ttaatggggt tgttgagcgg tatctatgaa tggccgatct tggtcacctt cttgaccttg
     8281 ccaattgtga agaagcattt ggatcaattc aagcaaacgt taccccagcc tatcagtttc
     8341 agctattcca tcaaaaatat ggtcttattc aatgccagtt atgtattggg gctattacta
     8401 acaatcatta tgcaagccat ttaacagcat gaagaggttg tgaaaaaact gccctgcatc
     8461 aagtaataag aacagccaaa taaaaatagc tccttatatt tttcgtttgg ttgggcttat
     8521 taccgcagat gcaagctttt gaacaccgtt tatcaggagg ttgtgaaaaa gtcgcttagt
     8581 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct
     8641 taataccgag aaactggctt ttgaacaccg tttatcagag gttgtaaaat cagtgttttg
     8701 tcctgagtat tagagaaaca aatggaaaaa tagttcctca tattttgccg ttttttgagc
     8761 taataccgaa ggacagctga ttgaacacta tttgttcgga aaaagtgact aactatgaca
     8821 caattttttt cacagtccct tttttcactt gatttgattc gtaccagcga acttgacgag
     8881 aactttcttg gtttggtaac tatatggtat tcttttaaca tcctcgtttg cttcttctaa
     8941 tttatttata caaagtcaca cttttttaaa catctgttct tcgatacatt tctatttctt
     9001 ttaaacatcg ataccaatat tttgaactta agagtgcata ccaaatggat tcatttactc
     9061 ttcgtcagtt acgaagataa tcaaaatctc caacttccct acttatttcg ttttgagaat
     9121 tatcgaagca atcttacata aataactaaa aaacaaaaaa ccagaaaatc agtatactga
     9181 ttttctggtt ttacatggtt tgttcaataa aaagctgttg gaactgttaa tattaaatta
     9241 tcgcatcgtt acgaattctt ccgctcctgt tggatggatg gctactgtat tgtcaaagtc
     9301 ttctttagtt gcacccatct tgatagccac ggcaaaacct tgcagcatct catcgacacc
     9361 aacaccaata gcatgtaagc cgacgattct ttcttctttt ccgacacaga tcaatttcat
     9421 ttcgcatttt tggcgataat catttaatgc aaagtacatt ggggtaaagc gtgaacgata
     9481 aactttcaat tcattttcgc catatttttc caatgcttct tcttctgtca aaccaattgt
     9541 tgcaattggt ggatgcgtaa agacgactgt cggaacaagt ttatagtcaa gataagaatc
     9601 tttctttcca ttaaataaac gttctgataa acgtctacca gctgcgattg caacaggagt
     9661 cagatctaat ttaccgatca catcaccaac agcaaaaata tgttcatccg ttgtattttg
     9721 gtatttatct actttgataa accctttttt gtccaattcc acatttgtat tttccagacc
     9781 taatttttcg gtattcggta cacgtccacc ggcaaaaagt acacaatcac cagttaaggt
     9841 ttcaccattt tcaaatagca ccgtatattc gtcattgttt ttagtaattt ctttagcaat
     9901 atgatgtgcg taagttttta ttccagcttc ttggtacatt tggatcaaat tgtccgaaag
     9961 cattttatca aacgttctaa gtggtcgttc ttttcgatat gcccacatga cttcactacc
    10021 taaaccacga aatacacctg aaagttcagc cgcaatgtat ccagcaccta aaacgattgc
    10081 tctcttaggt aactctgtta attcaaaaaa tccatttgaa tcaattgcgt attctccacc
    10141 aggaatggtc attttacttg cacggcctcc agtagcgatc aagattttag gagcacgata
    10201 ggtttcaccg tttacttcga tcgtttgact atcgataaaa gtagcgtaac cttttatagc
    10261 ctcgacatga ttgctatcta atcctctttg ataagcaccg tgtagaaaat caatatattt
    10321 ttctcgtctt tctactagac cggcgaaatc aacatttttt aaatctgctt ggataccgta
    10381 acttgaggca tctcgttcaa ttgtttccaa aatcgtactt gcttgccaca taactttttt
    10441 aggtacacaa ccgacgttga cacatgttcc gcccaattca ttcgcttcaa tcagcaaaac
    10501 ttttgcgcca tgcatccctg ctctgtttgc tgaagcaata ccgccagagc cgccaccaat
    10561 tacgatgtaa tcatatattt gcattttgtt cctccttatt gaagagatca atcaaaacct
    10621 ttatttaacg atcctttttc tacagaaaac aagtgtaaca cttttcttga attttgtatg
    10681 cgaagatgct taaaacaggg atatatcagc tttttcctta tttacgtttt cggatcatat
    10741 ctccaggttt caccggctgt gcgactggca tagttaaaat catcattgga tttggtgctc
    10801 ggtcaatgga ttcgccttct tcattatgca taacttcaac ggtttgactg aaatgactga
    10861 atcctggacc ataaaattcg atttcatctc ctacagaaaa caagtttctc tgacgtatcg
    10921 tagcaatctg tgttgcctca tcataagata atacttcacc gacaaattta tatactggga
    10981 ttttacgacg ttcaccgaat aattgttcgt tttcagttgg tgtattgtag taaaaacctg
    11041 tagctaattc tcgttgtgct actttccata actcgtcgat ccattcttgc ttgcagacat
    11101 agttttcagg atcttccata taactgtcta cagccgcttt atagacattt gacaccgtag
    11161 atacataatg gatcgatttc attcttcctt cgatcttgaa gctgtctacg ccgttttcaa
    11221 tcaattctgg aatatgttcg atcattgaca tatccactgc actcatcgag aattcttctt
    11281 ccacttcgcc tgtatcagtt aaactgtttc gttcttgacc aaaaggcata tcgaacaatc
    11341 catacttcca gcgacaagat tgagaacatc cgccacggtt tgcatcccgc atcgacatat
    11401 ggttggacaa tgtgcatcga ccagaataag agatacacat ggcaccatgg ataaatgctt
    11461 cgatttcggt atccgtattt ttacgaatct ctgccacttc ctccattgaa acttcacgag
    11521 ctaaaacgac acgttccaac ccttcttctt tccagaattc caatgtctca aaattagttg
    11581 ctgaagcttg agtggataaa tggatcggca gacctggggc ttctgtcgca caaatttcga
    11641 tcaaagctgg atcagaaaca atcactgcag aaataccgac atcacgcaaa ctgcggaaaa
    11701 attcccctgc tccatcttca tttccttcat gggtgaccat attagcagca acgtatacct
    11761 tcgcatcatg ttcttttgca aaagcaactc cttcagccat ttcttcataa gtaaaattac
    11821 ctgcacggct tcttaaacca tatgcattcc cgccaatata tactgcatct gctccataat
    11881 ggatcgcggt ttttaacttt tccagtgttc ctgctggcgc taggatttct ggtcgtttca
    11941 attttctttt tactgtcatt tctttcatca tactccttat ttgatagcag aaggatcaat
    12001 ataaaagaat cctgtatcta attcacggtt ttcaggatgc aatttactga tttcgctagt
    12061 cattttttcc gctttttctt gatcccagct accttctaaa atttgttttt ttgcttcggc
    12121 gaatagtcga gtgatgttta cgaatttttc gcctggagta aataatccgt ccaatttcca
    12181 tgtacagtaa tgatgctgat aaagttcatt caattcattc gagagattca gatcattgct
    12241 ggcaaaaata tgtgtgccat gactatcttc ataaatagaa taatgtgtct cttctttttt
    12301 aggttccgag ataaaaagac ctctttcacg atctttttgt tcgtcttgtt tcgtatagtt
    12361 atagtaattc tgtagcagtg gacgtttgga ttgatggatg catgtagcac catacacaag
    12421 ggtttctaca ggaatatcga gtttttcttc catcgccttc atctcttcaa aaggaacttc
    12481 acgagcaagt actgctccaa ctgcgccttt tttcgcccag aaattgattt gacgtgcgct
    12541 cgttactaat gtttcagcat cataaatata cggtatacgc aattcaggat tttttttcat
    12601 cgtataaata atacctgtat caccaactgt gatcacatct acgtttattt cttttaaaaa
    12661 agccaaatat tcaggtacat ttttcatttt ttcaggatga atgatcccat ttacagcaat
    12721 attcgctttt ttaccatact tgtgtgctaa ttctaccaat tgtcgctgtt cttctcgtgt
    12781 aaatgaagca ggcagacgca atccaaattg ctcttcaccg aaatatagtg tatctgcacc
    12841 tgcagcaagc aactgttctg cttgttcaat agtttctact gtggttatga gttcgatcat
    12901 aattttctcc tcctacaact tcataatagt agcatagctc taaaaacttt ccaatacttc
    12961 ttctatttaa agtcggattt ttgaaaatta tttcacaaaa aatcaaaata aagttcgata
    13021 tattctgtcc aaatataaaa agagattgtg acaaaaatct tgtcacaacc tcttaatcaa
    13081 gtcttactat tataaaaatt cagctacaca ggccaagtaa ctatagggaa cctactgttt
    13141 cctttttagg tccgcgaaca ttcaatgtga tcttaccttt tgaagcacct actgttacgt
    13201 ggtcacctaa acgaatttct ccgccaagca aagcctcgct caatcgatct tcaatttctt
    13261 tttgaagtgc gcgacggatt ggacgtgcac catattcagg atcaaatcca gctttcccga
    13321 tcacatcgat tgcagatggt gtgattttca cttgaatatc ttgttctttc aatcgtttga
    13381 taatcgcttt gctcatgatt tggacgattg tatggatttc atctttactc aatgaatgga
    13441 agacgacagt ctcatcgatt cgattcaaga attcaggtcg gaaagctttc tttaactctt
    13501 ctaagatacg tttttgcatg gctttgtgat ctttagtaac atcttggaca ttgaatccga
    13561 catttttttc ttctcgaatt tgtgtcgctc cgatatttga agtcataatc atgattgtat
    13621 ttctaaagtc cacttttcta cctttagaat ctgttaaatg accatcatcc aatacttgca
    13681 gaagtaaatt gaaaacgtct ggatgtgctt tctccacttc atctaagaga atcactgaat
    13741 atggtttttg acgaattttt tctgtcaact gtccaccttc atcataccct acgtatcctg
    13801 gaggagaccc gattaatcgg cttgtactgt atttttccat aaattctgac atatcaacac
    13861 ggatcagggc atcttcactt ccaaacatga cttctgaaag tgctttggcc aattctgttt
    13921 ttccgacacc agttggtcca aggaacatga atgaaccaat tggacgatca ggatctttca
    13981 atccgcttcg tgcacggcgg atcgcacgtg aaactgcttt gacagcctca tcttgaccaa
    14041 cgacacgttc atgcagaagt ccttccagtt ctaacaagcg ttcgctttct tttttctcca
    14101 actgctgtag agggacacca gtccactccg atacaactgt agcaacatct tcttctgtta
    14161 cacgatcaga ataaccttgc tcctgttttg cttcaattgc agaaactttt tgcagctttt
    14221 tacgtagtgc tttttcttgt ctgcgtaatt gagcagcatt ttcaaagtct tgtttttgga
    14281 tcgctgcttc cttttcttgt actagttcat cgatttctag tttgatcaca gttgattttg
    14341 ttaagtgatc ggtttgatcc aaacggactt tcgctgctga ttcatcgatc aaatcaattg
    14401 ctttatcggg tagttgacga gaagtgatat aacgaacaga aagattgact gctgctcgta
    14461 cagcttcatc tgtgatctcc actccatggt gctcttcata tcttgtacgt aatccttgaa
    14521 gaatcacttc tgcttcttca ggagttggct catctacttg aatgcgagca aaacgtcgct
    14581 ctaatgcaga atctttttcg atatattttt gatattcatc tagggtcgtt gctccgatcg
    14641 tttgtaattc tcctcgagct aacgccggtt tcaagatatt cgaagcatca attgctcctt
    14701 ctgctccacc tgcaccaatt aaggtatgca attcatcaat gaataagatt acttgaccat
    14761 cattatagat ttcgtcgatg acctttttca ttcgatcttc aaattcaccg cgatatttcg
    14821 taccagcaac caaagatccc atatcaagca tcatcaggcg cttttcttgc atgtcttctg
    14881 gcacttcacc taaaatgatt ttttgagcta acccttcagc aatggctgtt ttgcctacac
    14941 caggttcacc caccagtaca gggttattct ttgtccgtcg gctaagaatc tggataagcc
    15001 gtttcacttc tctcgaacga ccaacaactg ggtccagctt gttttctttt gctaatttcg
    15061 tcaaatcacg tgctaatgaa tctagcgtag gtgttccttg cggtgtttgc cgtttatctt
    15121 gtacatttac atttctacga cgattcattc cttttccagc agaatcacca gctagcccca
    15181 ttttttgttt cagaacttga cgggcttttg aaaggctgat acctaagttg atcatgattc
    15241 gagtagccat gatactttca tcttttaata agctcatcaa aatatgttct gttccaactt
    15301 tttgagaacc agttttcttc acttcgctgc tagctaaagc aaaaacttgt ttcattcttg
    15361 gtgaatatgg aagaaagact cctttagggt aagaacggat accaccataa ccaatcagat
    15421 gttcaatttc ttcataaatt tccgtttcat tcaaatccat ttcacgtaat acttttccag
    15481 caattccatt ttgctcgacc actaaggcta gtaaaacatg ttctgaacta actgattgat
    15541 gtttcaaccg ttttgcttct tcttgtgcaa tttctaatac tgcttgggct ctttcagtaa
    15601 aaagttcttc catctaatct cacttcccat cttcataact taaacgttcc agaaatgctc
    15661 ggagaatccg agcacgtgta tgatcttcat attcattgaa attcaatgtg ttttttgcaa
    15721 ttgcactcaa catcaagttt ccttcttttt ttgtaattat ttggtcttca taaagttttt
    15781 gaataatagc aaaagcattt ttctcactga ttgtatcatc aaataactga tttatctgct
    15841 caagtaattg ttttttatct gaaatcctta cttttgcaat tcgtatataa ccaccaccac
    15901 cacgtttgct ttctactaga taaccacgtt ggatggtaaa acgggtatta atcacatagt
    15961 tgatttgtga aggaacacag ttaaagaggt ctgccatttc aatccttcga atctcgatca
    16021 tttcactatt ttccagaatt ttctttatat atgattcaat taaatccgag gtattctgat
    16081 gtgccatctt attcattccc tttgactaat attgacctta attataacga atttgataat
    16141 agaaagaaag aagaacgctt tttgttaaat aaatccttta gaatcaacaa aaaaaaatac
    16201 ggaatatact attccgtatc gacgcgccca agaggagtcg aacccctaac cttttgatcc
    16261 gtagtcaaac actctatcca gttgagctat gggcgcatat tcaatttaaa aaaatta
//
LOCUS       DAFLWZ010000062        15470 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000062 DAFLWZ010000000
VERSION     DAFLWZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.062"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            106..456
                     /locus_tag="L1V38_002104"
     CDS             106..456
                     /locus_tag="L1V38_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBN1316647.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            555..1085
                     /locus_tag="L1V38_002105"
     CDS             555..1085
                     /locus_tag="L1V38_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1316648.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            1239..2390
                     /locus_tag="L1V38_002106"
     CDS             1239..2390
                     /locus_tag="L1V38_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBN1316649.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(2499..4538)
                     /locus_tag="L1V38_002107"
     CDS             complement(2499..4538)
                     /locus_tag="L1V38_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBN1316650.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(4596..5153)
                     /locus_tag="L1V38_002108"
                     /pseudo
     CDS             complement(4596..5153)
                     /locus_tag="L1V38_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(5692..5898)
                     /locus_tag="L1V38_002109"
     CDS             complement(5692..5898)
                     /locus_tag="L1V38_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316651.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(5914..6528)
                     /locus_tag="L1V38_002110"
     CDS             complement(5914..6528)
                     /locus_tag="L1V38_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBN1316652.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(6675..7358)
                     /locus_tag="L1V38_002111"
     CDS             complement(6675..7358)
                     /locus_tag="L1V38_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1316653.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(7467..7925)
                     /locus_tag="L1V38_002112"
     CDS             complement(7467..7925)
                     /locus_tag="L1V38_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBN1316654.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(8009..9772)
                     /locus_tag="L1V38_002113"
     CDS             complement(8009..9772)
                     /locus_tag="L1V38_002113"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBN1316655.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(9993..11453)
                     /locus_tag="L1V38_002114"
     CDS             complement(9993..11453)
                     /locus_tag="L1V38_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316656.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(11661..12587)
                     /gene="glsA"
                     /locus_tag="L1V38_002115"
     CDS             complement(11661..12587)
                     /gene="glsA"
                     /locus_tag="L1V38_002115"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBN1316657.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(12610..14037)
                     /locus_tag="L1V38_002116"
     CDS             complement(12610..14037)
                     /locus_tag="L1V38_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316658.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(14068..15282)
                     /locus_tag="L1V38_002117"
     CDS             complement(14068..15282)
                     /locus_tag="L1V38_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBN1316659.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         4423 a         3093 c         2661 g         5293 t
ORIGIN      
        1 attttgtcac aatccttttt gtttttttga ataatcgctt tttcttctct ttttcttata
       61 tactataagt agtaaataat ttgaaaaaaa gaaaggtgac tgattatggc gcaaaatcgt
      121 atttttacga caagttttgc aagcgtttat cctatgtatg tagcaaaagc ggagagaaaa
      181 gatcgtataa aagaggaagt agatgaaatc atttgttggc tgacgggtta ttcccaaaca
      241 gaactagaat atcaactaca aaaacaagtg actttcgaac aattttttgc ggaagcccct
      301 gtccccaatc cttcacgttc cttgattaca ggtgttgttt gtggtgtacg agtagaagac
      361 atcgaggata acttgatgaa agaaattcgt tatttagata aaatgatcga tgagctagca
      421 aaaggcaaaa aaatggaaaa gatcctcaga agttgatttt tccagagata ttcttctcct
      481 tcgctcattt tgtaacattt aatttggtaa aatgactagt tcacgttaaa ataagtcaaa
      541 ggaggttttc ttatatgttt gagacgatta aacaaaatat tcaaaaatac gccttattaa
      601 gagctgctgt ttatattatt tctgggattg cgattgtgct aaacccttct gctgtttttc
      661 attttatcgg ttatctgatc accgcctatc ttgttttgct tgggttgttg aatctttttg
      721 aggcttaccg ttttaaaagg aaaacaggtt cttggagtat cggtctgttc agtggtcttt
      781 ttttcctgat cttagctctg atcgtctatg cttttgcacc tgcaatcgtt tctatcctgc
      841 cgattcttct tggattagct gttatcatca acagcttgtt ccagttgttc ttcagcatga
      901 atacaaaagc taaaagttgg agtgtttata gtagtattct gttgttgatt ggcggattcg
      961 tcttattgtt caatccattc aaaagtttga tgcttctatt ccaaatattc ggctttattt
     1021 tgattttcat gggcatccag gagattatca atttcatcag aataagaaaa atgactatac
     1081 gttaatcatt tttagttatt aaaatagacc gtataaaaac caacaatcca aaaaaatctt
     1141 ttggattgtt ggtttttttg tgagtatatt ttcctatttt ttcaataatg tatgttatgc
     1201 taagttcggg ctatatttta tacaaaggaa tgatgagaat ggaatttatt ggtattttat
     1261 gcctgatatt gatttcaaca acgattggct cacatatctc gcggagatta ggtatcccag
     1321 cagtgattgg acaattactt gttggtgttt tgctaggcca agctggattg aattgggtca
     1381 aacctgatat tctagtccat gacttttcgg agattggtgt gttcttatta atgtttttag
     1441 ctggtctgga aagtgattta tctcttttga aaaaatattt ccgacctggt atgttcgttg
     1501 ctttgcttgg gatcatcttc ccggttgttt ttggctggtt gacaggcaaa gcattccaag
     1561 tttcgggaaa tgaagcgatt ttctttggga ttattcttgc ggcaacttct gtcagtattt
     1621 cagtagaagt attaaaagaa ctaaacgtag tgaatacaaa agaaggatca acaattttgg
     1681 gtgcttctgt ggtagatgac attttagtcg ttttagttct aagtttcagc ctatcttttc
     1741 taacggggga agcttctagc aatgcttctt taccgcttgt tttgattgaa cagctaattt
     1801 attttgtttt tattttctta ttagtcaaat ggattgcgcc tttcctactt tcatttgcag
     1861 aaaaagtgta cgcaaattct tctattatca tcgtatcgct agttatttgt ttaggaatgt
     1921 cttacgtagc ggatcttgtt gggcttagct ctgtcattgg tgcttttttt gctgggatag
     1981 ctgtcagtca gacaaaggtt aaagaagaag tataccacaa tgtagaggct ttaggatatg
     2041 cagtatttat accagtattt tttgtcagtg taggattaga agttgatttt tctgacttta
     2101 gtgaacaact actctttatt tctatattga cgcttgtagc gattttgacc aaattgcttg
     2161 gaggttattt tggtgctcag attgccggtt tttctcaaca tagttcattg atggtcggtg
     2221 ctggtatgat ttcgcgtgga gaaatggctt tgatcatttt acaaattgga cagcaaagtc
     2281 aattgatcga accacagtac tattcacctt tagttatcgt gattttatta agtacactta
     2341 tttctccact tgttctcaaa tattttacaa aaaaagttta tgaagtgtga gtaaatcaaa
     2401 aagaagttgt gaaagagaca tcgtgaaaac cgtttatttg aaaaaaggac tgtgacgata
     2461 acgccacagt ccttttactg tacttaaaaa gcaatttttt attgataatt ttggttgagg
     2521 tattgcaata gttccgatgc tcgtttggtt gctgaatcat catcatcttt attttccaac
     2581 atgctgacca tcatataacc ttggttatca agattgaaag caaacaagaa actgttctct
     2641 tgccccttta catcctgttt ttctttgatt tccgctgtac cagttttcgc tgccaacgga
     2701 atccctaaag cagaaagaga atgtgctgta ccatttacat cttgcacaac ttctctcaga
     2761 tctggcacga tcgtttgtac tgctgtttcg ctgatgacat tcttcttatc ttttgtctct
     2821 ttatctgcaa tcaatttagg atagacaagt gtgccattgt tggtaaaaac agaatacatt
     2881 gctgcttgct ggataggagt aattagaagt tcgccctgtc catatccagt atcagctagc
     2941 aagatatctg agttaaagct atcttcatta gaaatttgtg ctggattcat actaattggc
     3001 aaatcaaggt cttcaccaaa aatgaattta tctaagcctg tacgaaattt tttctcaccc
     3061 attttcaacg tttcttgtgc cgcatatata ttatcggaat agatcaaagc agtttttaag
     3121 tctacttgtg atacatcact actgacacgc gttgttttaa aagatcccca agaactgtct
     3181 ttttgccatt taagcccgtt gatcgtcaac acttcatttg gatcgatagt gccgttgtcg
     3241 agaccgattg ctgctgtaat tattttaaac gtagatccag gagcataacc tgtcgcaaat
     3301 cggctgatga atggatgttc aggattttct tcataagctt tgtaatcttc ttgtgagatc
     3361 ccgtttgtca ttttgtttgg atcatagctt ggagagctag caagcgcaag aagatcaccg
     3421 gtttttggcg ttgtcgcaac agttgatcca gcttttcctc ctagactgtc aaaagctgtt
     3481 ttttgtgcct tcgcatcgat tgtcaatttg atatctttgc cattttgaac ttcatgttcg
     3541 atcagaactt ttttctctac accgtctgca tctgtaatgc ttaatttctc acctgttgtc
     3601 ccacgaagat ccttatcaaa agccatctcc aaacctgagc gaccgatttt tccattactg
     3661 cttaattctg gattcttatc aatatcttct gctgtgatat ctcccacgta accaatcagc
     3721 tgagcagctg cttcacccaa aggataatat ctgccgtcta cttcttgaat ggtagctcca
     3781 gctggaagtt ctggcgttgc tccatcaatg attttcaatg ggacaaagta atcgggttgt
     3841 acccagcttt gtgaaatcgc ctgattgata gcatcttctg ttaagtcgaa ggaggaagca
     3901 atcgctttga tattggctgt tttttcgcct ccatctccaa gtttacttgg aacgactcct
     3961 aattgtttta gtttgcctgt tgttgctaat ggttcaccat ttcgatctat aatattccct
     4021 cttgctgctt cttgtgtggt caggcttact ttgtcatttc cttccatttc tggaaaaacc
     4081 aagttgggtt gccagttgat cgtggtttga ccatcatttc tgtctaatgt tcctttataa
     4141 gaaagatctt tcaattcacc taatgaggta ttcatctttg ctttatatga aaaactgtaa
     4201 gtagaatcgt cttttttatc tacttttaga ttcgatatct gaagtccttt gacatcagca
     4261 gcaccgtata tattctggta ttgatctaag atctcttttt cagataatgc acttttattt
     4321 gccgcctttt ttgatgtcat ttctgcagct ttgttataat ctcccttgtt caaagcttgg
     4381 acaaattgct caactgtctt ttctccagct tctactgctt gggtttcttg atagtgctgg
     4441 tagtaaaaat aaccgccacc cgcagctgct attaagatca ctgcgccggc aatataagcg
     4501 cctgttcgat ttttgccgtg cttgtcactt cttttcattt tttcctcctt ctcttgcttg
     4561 tcattccttt atttcactat ttatacctgt ttattctaac atatgtcttt gaggaaatcc
     4621 ataccacaat ccagaagcac actttctgga aggttcgttt ggatactacc aagtaatttc
     4681 ccaaccgctt tgggtagctt gaatattgaa gttacgtctt tcagctgctg agagatagct
     4741 ttgatcactt gctgctgcct tctgatcctc ccgaagtctc cttctttgtc ttcccgaaat
     4801 cgagcatact ggagtaaagt attaccatcc atcacttgct ctcctttgtt tatatatacg
     4861 ccatctaaat ctagagattt ttctgcatcg atcttgactc caccaggaaa cagttcatta
     4921 acgcaatcga taaaatcttg aaatgtgata cttgcataat agggagcttc aaatttgaaa
     4981 ttttccttta atgtttgatt taataaatca actcccccat aagagtaagc tgcatttatc
     5041 ttattcattc cgtaacctgg aatatcgaca tatgaatctc tcatgataga gatcagtttt
     5101 gcttgttgtg ttttctggtt gtattgtgca accagaagtg aatccgagcg acctccacca
     5161 atcgatcttt tttcaccgca tctcctcctc acacagcaat ccacttgtca ggtgaggagc
     5221 gagtttgtct catcaaataa gtcagtcaca aaaatataaa gaaaaggtca gaaacctttt
     5281 cgaacaagaa ttctgaccta gcatcatctc atcgtccgag ttttagcact atacaacgta
     5341 aagaaaacat tcttagctat tggaaaaagc cttaatccaa cagtttctgt tttacccatt
     5401 ggcgactttc gacgtttctg ggcaacagcc tatgtttgta taggagcctc acctaacaag
     5461 gttattacta tattctattt acgagttcat gatagacttt tcctaatgat taggcaatgg
     5521 aatttgaaat gaaatagtga aatttaacaa tctttaatat tttttagaaa aaaataacaa
     5581 ataagttgaa agaatcccgt tgcaaattct ttcagttgca ccaggattct ttgataattt
     5641 tttagtttta tgtgtttttt tatatgtttt ttcacttttc ggaataaata tttatttgtt
     5701 aaagtaatta aacaatccgc taatcgtttg atctggcatt tctatttcct taccatctaa
     5761 agtaacagta gtaacgacaa aatggtcttg caatggcgga acttctaagt actgcccttg
     5821 cagaaaatca ttcactgttt catattcttt tttcatttct tttgaatctg tcgatggttt
     5881 atagcttatt tttaacataa ctagtgctcc tttttattcg ggacgtgcaa tcgtgaaaat
     5941 ttctcctatt gctgcataat catttcctgc caaacggctt acagcattca attttcttgg
     6001 atcgatcctt cctgtcttat catcatagac tgtttcattt aaatgatatt tctgtacttc
     6061 tagcaaaaat aaatcagctg ttactttatt tttattccgt atctcgacat gttcatataa
     6121 ggatgtttca aaacgaactt ttgcttctgt caatgctggt actgaaatga ttactgaatc
     6181 agttaaagtc aagtcagtca ggtacagttc gctttcctca ttaggcagat tggctgctgt
     6241 tttatttact tcttctacgt tgtcctcatc aaggatatgg ataacagctt ctcttgtctc
     6301 aagaatattc tttgctgtgt cttttactgc atcttgtttt ctctggatcg ccaaggataa
     6361 gatgggtcga ttcgaactga cgatattgaa gtaactgaag ggtgcgatat tcactatatc
     6421 ttttgctgat ttagtcgtta ctactgctac tggtctaggg atgactgaac caatcagcaa
     6481 cttgtaattt tcacgttctg tcaattctga aggactccgt tcaaacatgg tttcgccttc
     6541 tttctataaa attcgttaaa aagcagatct tgaagacaaa atgaaaagta atgctttttt
     6601 catcttctta gaatctgctt taaactatct atcaattttt cttttttgtc aagaatctgt
     6661 gccgtgcgtg ttttttagtt atttgcttta cttgcggctt cgacatatct tttagtgatc
     6721 aattgcggac gggtgataat agatccaact acgactgaaa aagcacctaa ttcatatgct
     6781 ttctctactt gttcaggaga gtcagtatgt ccttccataa ttactgggat atcgacttgt
     6841 tctatgattt gattcaataa atcaaaatca ggtgtctgcg tctttcgtga atattctgta
     6901 tagcctgcta aagtcgtaga caaaagatca aaaccatctt cttgcgcttg aagcgcttcc
     6961 tcaaaagtcg aaatatctgc catagctaac cgaccgtgtt cgtgaatcat ttggacaagt
     7021 tcagcagttg ttttttctgt cggacgttta cgagaagttg catccagtgc aatgatttct
     7081 gcttgcgtct ccaaaagttc ttccacttct ttttctgtcg cagtaataaa cacttctgac
     7141 ccatcgtaat ctcttttgat aatccctatt accggtaaat caacgattcg cttgatttca
     7201 ttgatatctt ctgtcgtatt tgctcgaata ccaactgctc cgccttcttt tgcagccaaa
     7261 gccattctcc ccataataaa agaactgtgt agcggctcgt tttccaaagc ttgacaagaa
     7321 acgacgactc cgcctttgat ttgttccagt gtatccacaa tatctcctcc agtaatgtta
     7381 tataaaaata cagcttcata taaaaatgta acccttttct attcaggaga caataatgag
     7441 ctatttcttt cagcagacct ttcttactaa aagaaaatta cttcaaattc ttcgtatacg
     7501 accagcttct cttctgtaaa ttctatgttc aacgcttctt tataagcatg tttaaaaaac
     7561 tcagcatgga ctttccgcca ataagctaat gtccgatccc cttctccttc tttccaagca
     7621 tgctctttcg tgacttcact aaaaggcaag atggtcacat ttatattttt gatgatacaa
     7681 actggttcat tttttccatt caggaccacg tctaattgac caacttttgg taaaggctca
     7741 ttctcttgtt tatacagatc gtaaccactt gatgtaccag tctttatctt ttttacaact
     7801 agttcgctca actcgtctgc cattttttct gtatccccaa atgaaaagaa acctaatttt
     7861 tctgattgat aactaggata tttttcttgg aactttttga catattcttc tacttgctga
     7921 tacataacat ccaccccttt gctttttata atgaaaaaac catccagata ctagtataaa
     7981 caattatctg gatggtgagc ataatgaatt attgaatatt caagacacgc agactatctt
     8041 caacgatttg ttttggtgtt aaatgataac gttcataaag ctgccctaca ggaacgctat
     8101 ccgtgaattc tttctctgca ccaaaattta atacgttcat tgaagaatca ccataataac
     8161 gactgatatt ttcgccaaat cctcctgaca aactaccatc ttctaatgtg atgactaatt
     8221 cgtgtgtttc ttttaattta tctaatgttt ctacgtcatt ttctgtgatc gttcctggat
     8281 tgatcaacgt tgcttcgatt cctttttttc taaaagcttt tactgtttct tttcctaatt
     8341 caagaaaacc gcctaaagct aaaattgcta cttttcctcc attatttact gtttgatagg
     8401 ctggaatact ataatcattt gcgatagctg taccatgttc tacaccatgt gtaggaattc
     8461 ggattgctac aggctgcgct gtttgttcga acgcccaatc tagcatagag atcatatcct
     8521 cttttgttgc tggagcaaga tatttgatgt tcgggatact tgataagtaa ggaatgtcaa
     8581 atgttccttg gtgtgttcgg tcactagctg agatcgttcc gccaccgact aaaataatca
     8641 ctggattctc gttgatcgct aaatcatgtg ataattgatc atatgcccgt tgcaagaaag
     8701 tacttgattg gaagacgact ggacgtactc cctgagaagc caaagcagaa gcgaaagtga
     8761 tagagtgctg ttcagcgatc cccacgtcaa aataatgatc tggatgtttt tcttggaatg
     8821 ttttcagtcc aaaggcgcct ggtatcgctg cattgactgc ggcaatagga gctgtacttg
     8881 tttgcatttt cttatccaaa taatccatga tgatcatatt aaatgtttct ccagaagtta
     8941 cttgctttgc ctccccggtg gacagatcaa atggtacatg ccaatgatat ttcattttat
     9001 tatcgattgc cggctgataa ccgcgacctt tttccgtatg gacgtgaagt acaatcggat
     9061 gatcaatatc ttttacttct tcaaataaac ggatcaccgt ttccagatcg tttccattat
     9121 ccacgtaacg ataatcaaat cccattgctt taaataggtt attgctgctt ttaccgttgg
     9181 tttgacgaag ctcagctaag tttttatata aactgccatg attctcatca atagacatct
     9241 cattatcgtt tactaatacg attagattgg attgtaaaac accaccattg ttcaatcctt
     9301 caaaagctaa gccaccactt agggagccgt caccgataaa tgctaccaca tttcctgatt
     9361 ctttcttcag atctctcgct ttagctaaac ctgttgctaa gctgatagat gtagatgtgt
     9421 gccccactgt aaaatagtca tgtttacttt catgttggtt ggaatatccg ctcacttcac
     9481 ggtaatgtcc tttttcaaaa ccattttttc gaccagttaa aagcttatga ccataagact
     9541 gatgggaaac atcccaaacg attttatcct ttggtgaatc aaatacataa tgaaacgcaa
     9601 tcgttaattc tactacacct agattcggac caacgtgccc acctacatcg ctgtcctttt
     9661 gcaagatttt ttggcgcatc tcttctgcca actgtttcat ttcctcaaca gataattttt
     9721 tgacatctgc ggggctattg attgcatcca atacatgtaa tactgtactc ataatacatt
     9781 ctctcctccg tactatcttc ttttaatgaa aatagatttg ttacacttta tctattctac
     9841 tacttagagt tgactctaag tcaatagcat tttaaaaaaa tttcagagaa agcttgttat
     9901 ataagtagat cttcgcacga atcaggactc aaataaaaac cttctacaga caattaaaaa
     9961 gctttgtaga aggtctccta attaaggtct catcaagaaa tatgtttttt taataggtga
    10021 agttcctgag caatatgata caaatggatg tttgcacctt ttaatgagat tggatagatc
    10081 tttgtctttt cagtttctaa tccattttga tagctagcag catcgcacaa aaccactctt
    10141 tttttcgcac atagacattc atcaggcaat tcttctaatg aacgaaataa aataggattt
    10201 atttcagcga tgccttcttc cgcatacaaa tgaaattggg ttcgataaaa aaattgtttg
    10261 actgaacttt ctgaaacaac aaaaatttct atttcctgtc tccccgcttg ttcactgttg
    10321 atcaaagaaa gacttttgac gaattttcga atgaaatttt cattccatct tagttggatt
    10381 tgatttttct ttttccactc ttccaatatt tctacaattt ttccgtacag aagttgttct
    10441 ttttctgata gaagatagat cctttccggt aaaaatactt gtccatctgc ccacaacgta
    10501 cggacaaatt gtaaaaagga ttgcttgaaa ataaaatttt ctgcatcgtc gatttcagcg
    10561 atactaataa tctgtaaaat caattcattc agtgataggt cattgagaac aaaattttta
    10621 taaacaactt cgaaatcttt tcttaacagc tccatgttct cattggtata atttctactg
    10681 ttgaacaaag aaaaaatata atagacatct tcttcttgta agtctagaat tcctttttgc
    10741 tcttccaatc cttgacagac taattgaaat aacggcttcg tttctgcgct tttcttatct
    10801 tcttctttca gtccaagggg aaatgccttt cttccgattg cgatctctat tcctcgtatg
    10861 ataaaggact tttcatcttc cgaatatctt cttttaaaaa aatgagtctc tacataatca
    10921 atcaactcgt tacaagcttc ttctacatac ggatttttat tttcatagcc ttcccaattg
    10981 acataacgta ctaaagctag caagatgttc cgcgagtcaa attctgggat aatgatttct
    11041 ttatttttca aataatcatt ttctttaaaa aaatccaata cgattttttt gattgtatat
    11101 actttgctca aagaaataaa ttcaagatca gccagttctg tactcgtgaa tataccatta
    11161 aaataataac ttaaaaactt taaaaaataa gattgaccgt acagaaactg tgtgagctca
    11221 gaaagagcaa taccatgttt gaatacgagt ttatacttat gcttctctct tacttgttct
    11281 tttatacaat attctagaca ctcggctaga ctttctagat cgtgaaggat cgttggtgta
    11341 gtcaccctta gagaaatagc tgtttgttcg atgtctattt cttggaattc aaataattgt
    11401 tcacacagat acacttttct aaatatattt cgctcgatgt aattttccag cattcctgat
    11461 acacgcctcc agtttttctt atgattttat ttaatcatat ctgtaaatcg tatttttgtt
    11521 tcctttttat ttagaaaagc cctttcaaaa accaataaaa aaagaaactg ggacaaaagt
    11581 caaacaagct cacaatttca gcctcattgt aggtagcttt gagccgtttg gacttttacc
    11641 ccagcctctt tcaagaatgg ttattcaaag atgtcagcgt ctagttcttt gactacatct
    11701 ttcaacaatt ggataccagc tgcgctgtta ccaaatggat ctagtgccgg gctgaagaca
    11761 cctatgccgt aacgatttgg cacagctgcc atcaacccgc cgcctacacc gctttttgca
    11821 ggtacaccaa catggacgga aaactctcct gattcatcat acaaaccagc agttgtcata
    11881 attgatttga cgattgtagc actttcttca gtaatgattt gtttgccatt ccaaggagca
    11941 attcctttat ttgccagcac agcagctaat tttgctatgc ctgtagcggt gacattgagg
    12001 gagcattgtc tgaaataagc atcgagtatc tccggtacgt ctccttcgat catttgatta
    12061 cctttcatat agtaagcaag agagcgattg atatcacctg ttcttgattc agaatgatag
    12121 atttcttcat tcaatgtgat attaggatca tcacagatct ctttcataaa tgacaagatt
    12181 cgctcaaatt tttcatctgc atctttaccg gcaatcaacg aggttgttgc aatcgctcct
    12241 gcattaacaa aaggattcat tggatgtttg cgatgattga tttccatatt catgatagaa
    12301 ttgaaggcaa aaccggttgg ttccgtgttg attgtttgaa agactttttc tattccgttg
    12361 tctttgattg ctaataacaa tacgggaact tttgacatgc tttcgatggc aaagcgcaca
    12421 tcggcgtctc ctccctcaat cagttgtttt gtatccaaat cataaatcgc catacctaat
    12481 tgtttgggat ccacttcagc taatgctgga atgtaatccg ccacttgtcc tgtttgataa
    12541 tagtggaaat tttttccaat caattgttct aattctttta cttccatttg aataaccagc
    12601 tttcattttt tatttttctg catgctggaa tttatgacgg catgcgtaga tcgtaaatgg
    12661 aataactaag acgataagat aagaaacaat cagaatcgtt tcataaatcc catgctgtcc
    12721 agctgcgata ctagcaggtg gaacaaatga gatacaaaaa gcaaaaagtg aagtcaaaag
    12781 acctaaacaa gcaacgatta cttttacaac ttttccgcct ggaacctgat aggctctttc
    12841 aagactgtca tctttaaaaa ccagcttcaa atagcccgcg aaaaacataa agtacaacat
    12901 caggtagatt acaacagtca atgacatcgc tgcaagaaat gaaagattat tccccccgcc
    12961 gcttaatgta aagacggctg cccagattgt tgcaacgatc ccatttgcga tcatcaaatg
    13021 agcaggaaca ccgtgtgtgt tttcttttgc aaaatattca ggaagtaatc cttcttctgc
    13081 tgctacgtga agtgcttttg aaggagaggt tacccaagaa gcaatttctc cgatgacacc
    13141 taaacaaaca agaatcgcaa gaattttcgc aatccatgca agatttggat caatgtgtct
    13201 taataggaat tctaacgatt gaatcacccc tgtattaaga gacaaaccat gttgaggtac
    13261 tgtagtagcg acggtcaatc cgccaaaagt atctaaaatg attgccagaa taaccaatac
    13321 aaacattgct aatggataat cctttttagg gttttccatt tcatttgcat gactggcaga
    13381 tgtttctacg cccatatatg ctaaaataaa ggaaacaaaa acaaccagcg taggcaattt
    13441 cgaaaaatca ggaatcaatg ttttcataga cagtatcgtt tgtagtggag cgcctgaagc
    13501 gacataatgg atccctaagc caaacaagac taatgctggc aacaagatac cagctacaaa
    13561 accgatccga gcaatcaatg aagtgtattt ggttcctttt aactgtgaga gtaaaatagc
    13621 ccagaaaata atcaatagga ttgccaattt cagatattta ttgttttgta tagcaccaat
    13681 acccgttgca taggataatg caccagttaa gaaatacagc atggtcaagt agccaactgt
    13741 tatctcaaac cattggaaaa agattgcggc aaaaccgaat cgttttccca atgtgcgact
    13801 gacccaagta tagacaccgc ctttttccca tcctttcacc gttgccatct ctgctgcgca
    13861 caatgccaca gggataaacc atagcaaacc gcctaataac aagaaaaata ctaagctgaa
    13921 gcctgaggtc gcgaatgtgg gatattcata taatgaaacg accattgaga tggtcatagc
    13981 caaaaagcca aagaacgtta atttttttgc aggaattttc gttttgcttt gttgcatgaa
    14041 tcttcctctt ttctatttga atttgtttca attgagtttg ttgccaaaga agaaaaagtc
    14101 caatccttct tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca tcgccgattt
    14161 taaaatcact gttgtcagca cataggcata cacggcagta atgatgacac caatcacttg
    14221 aatccctaag aagtaccagc tgcttggatt cgttagtaaa tggctgttag atgcaaagat
    14281 ccctatcaga atcgtacctg tgaatccgcc catgccatga acaccccaca catcaagtgc
    14341 atcatcccat tgtttctttt tacgaaaatc aacagcagca tgacagacga tacccgcaat
    14401 gatcccaatc agcatggcac tttttgcttc tacataaccg gcacaaggcg taatggctgc
    14461 caatccagca acggatcctg ttagtacgtc gacaaaatca aagccatttc cttttacttt
    14521 tgcaatgatc agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg aaccaaatgc
    14581 attgactgct tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga accagccaaa
    14641 ccaaagcagt cctgtaccga tagcagctgc cataagactg ctatgctgac ttctttctcc
    14701 taaaggaatc tttctttgac caagtgtgag gatacatgct aaagagccga atccagctgt
    14761 cgtgtggatg actgctccac cagcgaaatc tctaaatccc atctgatcca aaaatccgcc
    14821 accccatatc cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa taacaagtat
    14881 aatatagcct tttaaattca atctccctgc aaaagctcct gtcatcaaag gaacggtaat
    14941 cacgataaac atcagttggt aaagaaagaa cattaaaaat ggaatcgttg caccatgaaa
    15001 catgttgggg aagcttgtaa catgtctcat caaaaagaaa tctgccgggt ttccaataac
    15061 accgccgata tcccgtccaa aggccaatcc gaatccacca aatacccaca taatcgttgt
    15121 tatcccaacg gagagaaaag attgagacat gatcgttagt atattattct tccgtgctaa
    15181 tccgccgtaa aaaaaagcta gaccaggagt catcaggcaa accattgctg tacataaaat
    15241 catgaatgct gtatctcctg tattgatagg taatgtattc atttttttcg cctcctttct
    15301 acgattacga gtataaaaga aggtgtagtt gtttttttct tctgtttttt tgaattaata
    15361 cttgcattta taaaagacag acaattaata aaagcttgat gtgttgtgct ctttttcgtt
    15421 tttcacacaa ataaagacaa aaaataaacg gtcttctttt tatagaaaac
//
LOCUS       DAFLWZ010000063        15160 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000063 DAFLWZ010000000
VERSION     DAFLWZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.063"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..169
                     /locus_tag="L1V38_002118"
     CDS             <1..169
                     /locus_tag="L1V38_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1316660.1"
                     /translation="AKILPLLKEPEQIFLIEKFIFDKTDKEIGKVLGITRQGATNLKH
                     RLYKKIQKMLV"
     gene            263..454
                     /locus_tag="L1V38_002119"
     CDS             263..454
                     /locus_tag="L1V38_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316661.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            968..1300
                     /locus_tag="L1V38_002120"
     CDS             968..1300
                     /locus_tag="L1V38_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1316662.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1596..1751
                     /locus_tag="L1V38_002121"
     CDS             1596..1751
                     /locus_tag="L1V38_002121"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBN1316663.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2027..3367
                     /locus_tag="L1V38_002122"
                     /pseudo
     CDS             2027..3367
                     /locus_tag="L1V38_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3608..5224)
                     /locus_tag="L1V38_002123"
     CDS             complement(3608..5224)
                     /locus_tag="L1V38_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1316664.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            5342..5560
                     /locus_tag="L1V38_002124"
     CDS             5342..5560
                     /locus_tag="L1V38_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316665.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5755..6216
                     /locus_tag="L1V38_002125"
     CDS             5755..6216
                     /locus_tag="L1V38_002125"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1316666.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(6409..6648)
                     /locus_tag="L1V38_002126"
     CDS             complement(6409..6648)
                     /locus_tag="L1V38_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316667.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(6672..8195)
                     /locus_tag="L1V38_002127"
     CDS             complement(6672..8195)
                     /locus_tag="L1V38_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBN1316668.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(8213..8335)
                     /locus_tag="L1V38_002128"
     CDS             complement(8213..8335)
                     /locus_tag="L1V38_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1316669.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(8365..9348)
                     /locus_tag="L1V38_002129"
     CDS             complement(8365..9348)
                     /locus_tag="L1V38_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBN1316670.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(9372..9521)
                     /gene="rpmG"
                     /locus_tag="L1V38_002130"
     CDS             complement(9372..9521)
                     /gene="rpmG"
                     /locus_tag="L1V38_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1316671.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(9542..9919)
                     /locus_tag="L1V38_002131"
     CDS             complement(9542..9919)
                     /locus_tag="L1V38_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316672.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(9951..10130)
                     /gene="rpmF"
                     /locus_tag="L1V38_002132"
     CDS             complement(9951..10130)
                     /gene="rpmF"
                     /locus_tag="L1V38_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1316673.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10145..10414)
                     /gene="rpsN"
                     /locus_tag="L1V38_002133"
     CDS             complement(10145..10414)
                     /gene="rpsN"
                     /locus_tag="L1V38_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1316674.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(10937..12703)
                     /locus_tag="L1V38_002134"
     CDS             complement(10937..12703)
                     /locus_tag="L1V38_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316675.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(12663..14417)
                     /locus_tag="L1V38_002135"
     CDS             complement(12663..14417)
                     /locus_tag="L1V38_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316676.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(14527..15096)
                     /locus_tag="L1V38_002136"
     CDS             complement(14527..15096)
                     /locus_tag="L1V38_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBN1316677.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
BASE COUNT         4877 a         2916 c         2315 g         5052 t
ORIGIN      
        1 agcaaaaatc cttcctttgt tgaaagaacc tgaacaaatt tttcttatcg aaaaatttat
       61 ctttgataaa actgataaag aaattggaaa ggttctgggg attacaagac agggtgcgac
      121 aaatttaaaa catcgacttt acaaaaaaat tcaaaaaatg ctggtttaat atctgcataa
      181 taactaattt tgtatgcttc tttgctcgtt ctcctccttc ccaaagaaat agattataag
      241 tccatgggaa gaaggtagat ttatgaattc tttaaaagaa gatttcattt tagcaaaggc
      301 tggaaatgaa gaagctgttg aggcaattct caaaagattt agctctttga ttcataagca
      361 atcctggaga actggaaaat atgatcaaga ttgttatcaa gaatgtatgc ttgcaatata
      421 tctagctatc tcgaaattcg aaattaaaga ataactcaac taagggagtc tgtgacataa
      481 gtaaaaagat agtttcaaat ttcgaacaat aaatttgaaa ctatcttctt tataattata
      541 aagtatcgat tttacagcgt tctataatga ttcatagaat ctaaaacgaa tgattttaat
      601 tatcaacgtt ttttaattcg tttttagctt aaaaataact tttgtcacag tctcactcct
      661 aaaattactt tatttacgta tgaagtgggc aggaggtcga atccagaact gggctatggt
      721 acttcaacga ggacttctcc tctagaattg aaaagcatgc gatttacctt ccgtaacgac
      781 ggtagattta ttcaactatg tgtccaatca aaatttgtct gatttcaaaa atagtcaaga
      841 gaattttggt tgttaaaaac tcttatctat caacttccac agtttagttg acaaaccctg
      901 atactaagtt gggctatgat acacttttct tgactatcag ttacgttacc ggaaggaatg
      961 aactctattg agaaaaacat atgatcgtaa atttaaacta aagatttcac aggatatcct
     1021 tgagaaaaaa gtaactacca agaaaattgc tgaagaatac aatatctctc gtccaacaat
     1081 ttcccgatgg gtttcagaat atcgtcgata cgggaaaaat gcttttgctg gacaaggaaa
     1141 aagattacct gataaagcag atttctacat tcttgaacag gaaaataaac gactaaaaga
     1201 ggaagacgag tgttctacga acacaaagat cgatacggat ctccagggat cactcaaaaa
     1261 ctttacgatg aaggaatcga aatcaataaa cgtgttgtag ctgttcttat gcgtgaaatg
     1321 aatttatgca caagaggatt tcatcgacgc aaatcttctc atggtagaga aaaaacaatc
     1381 aaagaaatgg taaaaaaatg ttgaatcgat aatttgaaca gaaccaaatt gatgctgttt
     1441 gggtgatgga tattacttac attccatgta atgacggtcg cctctatttg tccacctata
     1501 ttgacttagc aactcgtatt ctacgttact atatggtaga ttcacacatg aaaaaagaga
     1561 ttgtcgtccg tccattacaa atttattaag gagaattgcc tacggtaatt cattccgata
     1621 gaggtagcca gcatcggtct tttatttatc aagagctgtt gaacgaccac cacatcacac
     1681 attcagtgag ccaaactggg actcctgttg acaatgcagt aattgaagcg tttcatcgat
     1741 caatcaaatg agaattaatc gactccaaca aatataaaag taaaatagag atgaaggtgt
     1801 taatccaaga ttatttagaa gactactacc caaacaaaag aatccataca aaatttatga
     1861 tgactccttg acaatttgaa gcgaagaaaa taagggatct ataatatcta gtgttggtga
     1921 cgccttctgt tgccaatact ttttcttttt tctaataaac gcaaacagac accttaaaat
     1981 cctttagaat aaagtcgacg aaaaccattc aaaggagtgt ttcaagatgt cctattcaga
     2041 gtttaccaaa gagttactag atattctaga cctaaatctt atctttcatg aagatgcctt
     2101 tcgcaaagag cgaatcaatg acgaaacatg ttttgttttt gatggcacat tgacctatca
     2161 accggaggaa tgctttcatc gccactatca aaatgaacaa acgatcatta aatagggctg
     2221 gaaaaaagta tccatcttat tgaatgatgt cagtaactac aagaccattc tgcggattaa
     2281 caaacagcgc ttcaaatgta aacactgtgg aaagactttt ttagcagaag attcagttag
     2341 tgatcgtcgc tgctccattg ctcgcagagt caaacaagcc attcttgagc tattaagcga
     2401 acctctttct atgtctttga tcgcacgtat gaagcacatt tctccgacca ctgtcattcg
     2461 aatacttcgc agccttcggc ctaaaaccat ttctttgagc cagctgttac cagaagtggt
     2521 gtgtttcgat gaattcaaat cagtgaaaaa tgtctcggga gccatgagct ttgtcatgat
     2581 ggacggcaag acccatcaac tgattgatat tgtggaaaat cggcaactca atcctttacg
     2641 cgactatttc ttgcgctacc ctataaaagt ccgtgaacaa gtgcgtctag tggtttcaga
     2701 tttctataca ccctatcgca cattggtgaa agagtgtttt ccgaatgccc gaatcgtcgc
     2761 cgatcgcttt catattagcc aacacattgg tcgggctttt accaaccacc gaattcaagt
     2821 aatgaagacc tttaaaaaag gggatcgtcg gtcgaagcac ttaaagaaat actggaaact
     2881 acttcaaaag aatgcgtggg aattgaaagg tcagcatcgc tactggcgtc cgtcatttcg
     2941 agatcatctg acagaagcag agatagtcga tcggctatta tcttatgatg attccttaaa
     3001 gcgaggctac gaagtctacc aggattttct ttccgttatc agaagacaag atgttcctga
     3061 attcgtcgcg ctcctaaaag aagactacaa ggagttgcca gagcactacc aaccagtgtt
     3121 cacgaccttc aagaaatacc aaacagaaat caaacgagcg ttgcgcgttc cctattccaa
     3181 cggccctata gaatgtttga ataaccatat caaagtacta aaacgaattg cctatggcta
     3241 tagaaacttt caaaactacc gagaacgaat ctttttatat cgaggaaaat attttaagaa
     3301 aactaagaat actacccaac tgactaaagc cagaacaaca acacggctag acaagatagc
     3361 tgtctagccg tgtgagtatc tcgattattc tattgaattt cttcaccaac actcattgac
     3421 gaagagccaa aataagtaat ctaaccgact gttaactaaa ccattgcagg tcccgttaaa
     3481 gatacttgtg cctgttgtca ccgcttcttt ttcttgtcca caagcgctta acacacttaa
     3541 taaagcccct gctattatta ataataatat ctttttctta ttaaaaacct cctcatctat
     3601 ttccagatta gtaaatgtag taatctgtgc tttctttttt ctcaatacta ataactaact
     3661 tatggggtaa acaaatactc gtttgaccgg gttttgagat ccatccagtt ctaaccgcga
     3721 tttgatcagg actattatct tctttaactc gaattcttcc atctttaatc tcaacaatat
     3781 tatattgtcc cttcgcagga tgataattca cgagtttatg attgatctta tccaaatcga
     3841 agcgatccat ttccttgcca tcaattcgaa cgatggcata tttgatagca tcttcagttg
     3901 tttcattctc cttttctata gagaatacaa ataagggaat aaaagaggta ataatcaaaa
     3961 tgccaataat tatgacatcg cctatcttga caccagcttt tcttaaaaat ttcattaacg
     4021 atatctggct aaacatatta gactttttcc atggaaatgg tgaaattttt cggaaattat
     4081 ctgcattaag agaatcagtt aaacaaccct caagttgttc cttaatacat tgttgatcca
     4141 tcttcatacc aataaaaact agtttattaa tgcgttcacc aaacaacgga tgccaggctt
     4201 ccttcaattc gggatttttt tgtataatca tttgacactc aattttaggt aaactagcta
     4261 cccaataatt taatgattca atacttttat agctacccga tgtttcaaag atcgtcgaaa
     4321 aatcactatg ttgggcaaac caaagaaacc cttttgctct tgtaatattg ccaggaaaat
     4381 ttttatccgt aagatgggca aatttttgtg cgtcaaggag taaccgattt cgatagataa
     4441 aacttgagat accatattct tctgtttcag gaatatgatt ttgatagcca agctctaact
     4501 ctttgaacca gcccactgaa taggaagtct catctatatt aaaaagattt gtatttagaa
     4561 ttttcgataa gtctacttca cctttaattg tcctaattat tttggcattg gactgtaact
     4621 tagcaattag accgttaatt ttgtaaatcg tcttggttga cactaagtca ctattattta
     4681 aaagtaatat gttacaacac tcgaattgat caattaacaa gccacgaata tcctgttctt
     4741 cttcaactac attaccttca gcttttcttt cctgaatctt ttcacccgtt tcgaaattat
     4801 cccaaaaacg ttttacatcc actactataa taatggcacc aatctctaat cgttgggtca
     4861 aatcaatgtc taaagggttt ttagctaata taattgcttg aataattgga attggtttgc
     4921 tgattcctga agcttcaata acaatttgat tcaagtcaga aaattgcact aattgatcta
     4981 gttcaacaat caaatcttcg cgtaatgtac aacaaatgca tccattcggc atcgaaacaa
     5041 gtttttctcc agttctttta aaacctttct tgtcgactaa taccccatca acatttactt
     5101 cccctatgtc atttacaatg acagcaattt tctttccgtg atcaccgtac agaatatgat
     5161 ttagaagtat cgtttttcct gaaccaagat agccagttaa gattgtaata ggtatttttt
     5221 tcatagggaa cctctttcta taccttgaat ttacacttta agtgcaacac ataaaaatga
     5281 gtcataatcg atatccaact agtataagtt tgtcgagaac actcctagaa ggaaaataat
     5341 tatgagccag tatcgtcatc ttactatact cgaacgagaa agaatctttc tgcttcacga
     5401 agaaggattt tctattagta taattggcaa cgacattcag catagcccgt ttactatttt
     5461 acatgaactg agaagaaaca agaaaaaaac tattcacctt ccaaagcgga aaaaaattat
     5521 gcttatcgaa gaaaaaaatg cggacgttat cacattctaa atgatccgtg agtttggtca
     5581 attgttcgtc atttatttgt cgattttcag tggtcgccag aggaaatctc gaatcgtttg
     5641 aagcatgaac atatggactt ttcaattagt tttatcacga tctaacgtgc aatttgcaat
     5701 gatcttttcg atacagaacc cctctcacac ggcaataaag gcctgatccg ttcattgcac
     5761 catcgaggaa aaacaagaca tacaaaaaat catgtcgagt ctcgtggaaa gatttgcctt
     5821 actcattcga tccatggccg tccaaaatcc gcagatgata gaagtgattt tggtcattgg
     5881 aaagccgata ttgtagctgg caaaactggt ggtacttgtt tagtgacttt gacagacaga
     5941 aaatcatgct tccttttagc aggaaagaag gtccccagaa agaaagccgc ttatgtgagc
     6001 gagaaaatga ttgaactttt aagcagtatt ccaaatgagg cggtcaaaac gatcactcca
     6061 gatagaggaa aagaattctc caatcatttc gcagttacag aagcattgaa taatatgccc
     6121 ttttattttc cagatcctca tgcccttggc aacaatgaac aaattaaaat acgaatagac
     6181 tcattcgaga atacttgcca aaatcgaaag agatagctac ggtagataac tcaacgataa
     6241 atcagatgat tgaaaaactg aataacagac ctagaaagtg tttagattgg agaacacctt
     6301 atgaagtctt ctttgataaa gtgttgcgct tgatttgaca attcaagaca taataaaaag
     6361 cagatcaaat ccaaataagg gaaaaatgat ctactctggt attatcaatt aattggccaa
     6421 gctattatgc cgttttgcta aacgtctact tcttccagta ttgaccttga taaaacaaca
     6481 atcaggatcc cgttttaata ctctatgaac tgtgtcaata ctaacatgta aagttgcagc
     6541 aatatcagct aatgtactcc catttaatct catttgcttt gcaaatcgat aacgccgata
     6601 agcatcaata ttcttggaat ccatagacaa taatactttt cttaccatgt atttcctcca
     6661 aaaattgaat tttaatgagc catcatttct tgagcaattt catgtttaga caatgaagct
     6721 ggatagaaag taggccaatt atgcaattca ttatagagtt tttcttgact ttctccacca
     6781 aagaaaatat ggaaatgctc tgccttactt ggtgcaattc catgatcact aaattgaata
     6841 tatttaaaac gaccagcacc tgcatcatca gtttcaaaat taaaacgaac accacggttt
     6901 cctttttcat aattcaaaat tttgtatcca acatatttgt atgtgtattg atgatgttca
     6961 ccgttgacta caaaatcaat ggtgttgtct ttaatgttga tagtatcaat atctgtctta
     7021 tagccagtag tataataatc tttgtactcg gcagctgtca tgtctttatt gatttttgct
     7081 ttgtaatcga aaacttcatc caaaattcca tcttttaaca acggataaac agattgccat
     7141 tcgcctgtat aatcactcaa ttcgcgatcc ttcacatcgg catctttaaa gtacccatta
     7201 gcaactgtct tttcatcctt cgcttctttt tctggaacta cctcttcacc agcaaccata
     7261 gttgtttttt ctaacgcttt tagattgtct tccattactg aaacataatc ttcaccatta
     7321 tccatttgtt cttttgtaag actttcaaga ggattcagta cttccaattt tatcccagct
     7381 tcgttggcca aagtttttgc aattttatca ttagcattct tttcaaagta aatataattg
     7441 atcttatttt ttttaacata ctcttttaat tcagctaatc gaccagaaga tggctcttct
     7501 tcaggactta gtccagcaat aggaacttgt ttcaatccat aatccaaagc taaatatcca
     7561 aaggctgcgt gttgcgtcac aaaacttttt tgtttcgctt ctttaagact agtggtatag
     7621 tcagcatcca accgtttcag tttagtcaaa tacttttcag catttgtctc aaatactttt
     7681 gcttttttcg gatacaattt aactaactga tccttgatat ttgaaacttc cttaattgcc
     7741 attttgggtg aaacccacgt atgaggatct agttcatgat ggtgatcttc ttctccgtga
     7801 tcatgatctt cttcttcact acctggcaat aaaatcatgt cttttgttcc ttctactaca
     7861 ttaggcccag ctttcttcca actttcttta gcttttggta cccatgattc catgttttcg
     7921 ttatgatata caaaaacatc agcatcatga gcttttgcca tatccttagc tgagggctca
     7981 tagtcatgag gttctgatcc cgctggaacc attaaatcca cgttcgcttc atcgccgacg
     8041 atgtttttgg tgaaatcata cattggatag aatgttgtta caatttctaa ttttccatct
     8101 ttatcattcg atacttttgc atcattagtg ctggagcaag ctcccaataa tcctagagct
     8161 gctatcccaa taagtcctac actgattttc ttcattcttt ttccttcctt aattatgcta
     8221 atttcttcat tttatttcgt ttatgttctt tgataatttt taatgccctt tttctagttt
     8281 taatattcgg gcttttaagt cgtcgatatg cactagatat atccgttttc tccattagaa
     8341 attaccccca atcactactt atcattattt gctttccgcc agtaatttat caaaactctg
     8401 tttgatcctt tcttcatcca acatttttcc gattagaata atagtggttt ggtctttttg
     8461 tcgagtggtg tattgaaaat taacctgttc gtttacctct tgcatggcaa ctataaaatc
     8521 ctgctcttgt aaagcaatca atcctttaaa acgatacagg ctcccttggt tggttaaaat
     8581 cagccagtca atccattgga gtaaaaaatc tttttttatg tcttgatctg aagttaagag
     8641 aattgattta aactcatgta cttgatggtg ttgatgatag tatttgccat tatagtgatt
     8701 ttctgatgaa tcactttcaa aaactaaggg atgattaaat tttttcaaat tataaaaatc
     8761 ctttttttga atcgtttcac tatgtgtgaa cattcgaata tcggataaag ggttaatact
     8821 tttgatttct ctctgtaatt tttttagtgc agataaattc aagttttgtt ttctagacac
     8881 aaaaatgcga tctgccatga caagttgctt aagggcttgt ggttctcttt caataagttc
     8941 aaaactgtca ctatcaataa cagtcaataa actatcgata tatactcttc ctcttagttg
     9001 aggcgctgtt aaaagtgttt gaatgattgg ttggggatct gctatacctg tagtttcaat
     9061 gatgatttgt gaaattggtt gttgatgttc ttctattgtt tccagtaaag aaatcaatat
     9121 tgctaataaa tcactgcgaa gactgcaaca catacatcca ttatttagtt gtaacacccg
     9181 ttcctcgcta tgaactaata atttgtgatc aatcccaact tcaccaaact cattttcaat
     9241 tataataatt tcttccctgg ggtagggtga gacttgcaag gcttgattga ttagcgttgt
     9301 ttttccagcc cctaaaaacc cagaaacgat tgtaactggt atgcccattt tgtcaccttt
     9361 ttaccactta gctatttcac ttctttaaaa attgcccgtc tgcgcaattt tggcgaatac
     9421 ttttttaatt ctaaccgttc agggttattc cgtttatttt tgctggtgag atacagacgt
     9481 tctccagttt cgacacattc caaaataata ttttgacgca taaatcttcc tccttcaata
     9541 cttatcgatc ttcaagatat gcttgaattt gttgtgcatc ttcaaaagtt aactcgccag
     9601 attccaattg tgaaactaaa ttttctttca tatcaacagg tatctcccaa taaccatcga
     9661 tacattgaaa taactcctcg tcatactctt caaaaattgg atagattctt aaaaaatcat
     9721 caaatgataa gccttggtcc tcatagtaat ctttgactaa tccattttca attgcctgtt
     9781 gggtcggtaa acccgtttca gtaataattc ctctctctac catcgaacga taaaaagtgc
     9841 atttatctag cgattgctgg gtcgtttcaa gataatactt taatccttct tcaactaaag
     9901 gtgggtaaat aatttccatt ttgattccct cctaaaagtt atatattaaa ctattttgaa
     9961 gctcctttaa ttactttctt tccattatag taccctttta aagatacatg atggctacgt
    10021 ctataatcac cattcgcttc gtcaaatgaa atttctggtt ttactacagt ttgatgagtt
    10081 cttcttaacc gtttcttcgc cttagatgtt tttcttgctg gtactgccat gatatttcct
    10141 ccttttacca acttgctttt tttactccag gaatcaaccc ttgatgggca agttctctaa
    10201 acttaatacg ggacataccg aactttcgca tataccctct tggacgacca tccgtctgat
    10261 cacgaagcct cagacgattc ggatttgaat ctcttggcaa tttagcgaga gcggtgcgat
    10321 ctcctgcggc ttttaattcc tgacgtttat ctgcatactt ttcaatcatc gccatttgtt
    10381 tctttgcttt agcaattttc gacttttttg ccatatacct ttatactcct tttattttga
    10441 tttagacacc tcaaatcgta atcgttacgt tttgacactg atactttacc aacaagagtt
    10501 gctcttgtca acaataaata acatgaaata aaactcatat gaatagataa ctatttgaaa
    10561 acgaatttat cggtacatag agataatcaa atcatttaaa agaatatgca gtttaggctc
    10621 tgaaaaataa gaattcactt ttattagtcc aatcaaacac aaataccgtt ttaagtagct
    10681 tttcctctac ttaaaacggc aatatgaaag aaactataac tttttattca atcttttatg
    10741 tttaactggt ttatcgccaa ttttttaaaa ctttgattat tccttatatt ataagaatag
    10801 acattaagtg aactaattca atcatactga ttctttcgtg tattcaaaat tagatgctgt
    10861 ttaataaaat tattcttttt gaaaaagaat tataactata tcccaaaaat tgtaggttaa
    10921 tttaaagcct atttcatcat cgtgattgag cttctttttc atagacgaat ttctcagata
    10981 gtttagtttt ctttatgaga tttttgtata tttctgacct tcgatacaac tcattatgag
    11041 taccttgatc aactagtttt ccttgatcca tcactacaat tttatttacc ttttcaatag
    11101 acttcaagcg atgcgatata attagtactg tcttatcttg tattaaacga tttaaacttt
    11161 cctgaatacg tttttcattt tccgcatcta aactggcagt aatttcatct aaaattaaaa
    11221 ttggcgcatt tttcaaaaaa gcccgtgcta tggataggcg ttgtcgctct cctccagaaa
    11281 gtgaacttcc gttttctccg accaatgtat gataaccgtc aggtagtttt tcaataaagt
    11341 cttcgcagtt agctaaacga gctgcttttt tcacttcctc atctgacgct tgactatttc
    11401 caatacgtat attttccaaa atacttgtat taaacaaagt tacctcttga aaaacaatag
    11461 cgattttgct aaacaaagaa gctggagata cacgtttaat atcataccca tcaattaaaa
    11521 tacagccttc atcataatca tacagtctag acactaattt caagatacta gttttcccgg
    11581 aaccactagc acctactaac gcagtcactt ctccttgttt agccgtaaaa gagatatgat
    11641 ctaaaattgg ggtattgtta tcatatgaga aagagacatc tcgcaactca atgtcaaaag
    11701 atttcagagg actatctgat ccctcttgga tactggtttc cttcatagct ctaattcgct
    11761 gtattttagg agctaaataa aatatttcaa gcactgcttc tttcatagaa tcgaaggaat
    11821 cctttatttt tattgcggct agtaagtaac caacgacgta gagtatagtc acttcacccg
    11881 ttaacagtaa gtgaacacct actagaatga ctactgctaa actaacatat gagaaaatag
    11941 aggataaggc catgactgaa aaagtactta attctacctt taaatgaatc ctttcactct
    12001 cttccatttt tttgaaaagt ctgtcttgaa cttttttaga tagattaaag ctattaatct
    12061 cttgctgcaa ttctatagtt tcttgaaatt cttccgagtt ctctctcaaa gtatcgtaat
    12121 atttagtatt ggctttcgtt tgggatttct ttgataacaa gattaagaca aaactaaata
    12181 acgttggcaa aataacagct aatcccattt tgacattacc aaccaaaagc atcactgaaa
    12241 taaaagggaa aaacagagcc ataccgccgg ctttaggtat tgcatgactc atcgcatgct
    12301 caataccttc aacgtcagac atgatagttt gagataaatc tgataaatta tgttttgaaa
    12361 aataggataa tggtaaattt gacaaatcgt ctgcaatttg cactcttaaa tgcgcacttt
    12421 ctttataagt actattatat aagttttcat actccctatc taacaaccaa tacatgaaaa
    12481 gcaaagtaac aaacgatacg gcaaaataaa gccaacgggg ctttgtattt tctaaaacta
    12541 attcgtctat cagcatcatt ataatgaatg ctggtaccat attaatgcag tatacaaaaa
    12601 aactagaaat agaagcttta gttaaagctt ctgcgccctg atcacttaaa gcaaatttgt
    12661 ttttataaaa acttttcatt gtcaagcctc caatcatttg cattctcata attagtgacc
    12721 aattgtttat acacttgatg tttagccatt aattcattat gatttccacg ttctactatt
    12781 ttcccttctg acaagacaag aatttcatct acagatttaa tgctggataa tcgatgagct
    12841 atcataataa ctgttttttc tttcatcaga tgttgaaaag ccttttgtag ttcatactca
    12901 ttatctggat caatagatgc actggcttca tccataataa caatctttgc atcttttaaa
    12961 attgctctgg caatagctat acgttgtttt tctcctcctg acagataaac tcctttacta
    13021 ccaattaagg tatgctctct ttcgggaaat ttttctaaaa tcgattcgca accggctaat
    13081 cttagcgcgt caaatacttt acttgctggc gcttgaggat ttgctataga aacgttatcg
    13141 taaatactct gattgaatag tttcgtatct tgaaagacaa aagcaattgt gttaataatt
    13201 gtgtcttttg aatagtgatt taaaggctta ccaccaattt taatctgtcc cttatccaca
    13261 ttgtagaaac ctgaaattag tttagctatc gtactctttc cgcttcctga ttttcctact
    13321 aatgcataaa ttcttttttg ttctaaaact aagttgaaat tttctaaaac acactcttct
    13381 ttgtatgaaa agctgacatt ttcaaatgca atgtcacaat ttttaatctg tgtctcgttc
    13441 ccatatttta gttggtcttg cttcatttct aaataaaggg agtctagtgt ttcgactgca
    13501 tatcttgctt caaacaagtg catacttaca tacattattc tcatgaaaga aacaaaaata
    13561 attccactta aaaaaaacaa catcaacaag tcaacagcta atatcttggg agtggtaaga
    13621 gaagttataa aaaaggttat aggaactatc aaaatgcaaa ctatgccaaa aaatagccat
    13681 tgaaaaagaa caaaaggtgt tttcccactc aaagaatact tatatgcaaa cttagcataa
    13741 tcgttaattg ctttattcaa ggctttaaat gatgttactt tagcaccaaa tatctttata
    13801 acttgaattc cgcggatata ttctaccgtt tcagagctta acacatctaa cgattcttga
    13861 tatttttgaa taaaatttgt attctctgtc attttcttta acaagaatac accaattact
    13921 aacatggcga ttagaaccaa tccaatttta aagttaatga aaaagcctaa ggcaactgat
    13981 aaaacaggtg ttactatggc ttgagcacta tctggaatca agtgagcaat tgccatatgt
    14041 gttttagccg cgttgtcatc aattgtcttt cgaatatatc ccgaagaatt taaatcaaaa
    14101 aaacgaaaac ttgcttctgt taaaccgcta attccctttt ttctcaaatt agtctctaag
    14161 cgaaacccaa ggatatgaga aaataagcca gaaaaaatat aaaataaagc tcctaaagtt
    14221 aaccaagcaa cagtttgaac cgcataactc ttagctaaat attcatctcc tacaataatt
    14281 agagactgaa gaaatttgta aatactgtaa tatccataga ctgttaatac gacagaaaaa
    14341 tcagaaaata aagtggctaa ccatccgtag tatttcattt tagggacata actaaataat
    14401 tttttgtata ctttcatttt ttcctccccc gcattcaatt tcttctctta ttcgtttaca
    14461 actgttaatg ctttccgtaa tagcgtaaat tagagatgta caaacagata aaaggtaaac
    14521 tacgttctat tttttgtatt tttttaagac ttttcttcca atcaatacac caatcataga
    14581 taaacttgct acaactaaca ctgaaatgat tccccatata cctaccgcat agtggatcat
    14641 tgcatccatt gttgcagcag attgtccttt atctatccaa tcttgacgaa aacgatctgt
    14701 aaagaaccat ataggaatcc actgtccggc agcactgcct aattgcatta gagcccaaga
    14761 cgcaacttga ggaattgctc gatcatatcc aaatacagat agaataatat cagctaagat
    14821 cgccatacta atcgaactga taaaccaagg taagtacgcc ccgcccatta acgtaaaaaa
    14881 taacaataaa acaattgtgt aaatagtaaa aattcctttt ctagggtagt tatagctaat
    14941 ataaacaaat atgattccag ataataatcc aaaaatcccg ggggatatgc tgtgaccaaa
    15001 cgccccacca atactactaa ccattattga aaaaaagtaa attactaggg aaataactgt
    15061 agctaaacca ataaaaatat aatcttttgt tttcatatat attctcctca attctatttc
    15121 gttatgtcat taaaaatctg ttctatcaaa gttgaatctt
//
LOCUS       DAFLWZ010000064        14530 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000064 DAFLWZ010000000
VERSION     DAFLWZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.064"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(101..247)
                     /locus_tag="L1V38_002137"
                     /pseudo
     CDS             complement(101..247)
                     /locus_tag="L1V38_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            486..1178
                     /locus_tag="L1V38_002138"
     CDS             486..1178
                     /locus_tag="L1V38_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1316678.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
     gene            complement(1460..1532)
                     /locus_tag="L1V38_002139"
     tRNA            complement(1460..1532)
                     /locus_tag="L1V38_002139"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1497..1499),aa:Lys,seq:ctt)
     gene            1913..2482
                     /locus_tag="L1V38_002140"
     CDS             1913..2482
                     /locus_tag="L1V38_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBN1316679.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2469..3329
                     /locus_tag="L1V38_002141"
     CDS             2469..3329
                     /locus_tag="L1V38_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1316680.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3519..4223
                     /locus_tag="L1V38_002142"
     CDS             3519..4223
                     /locus_tag="L1V38_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1316681.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4228..6063
                     /gene="walK"
                     /locus_tag="L1V38_002143"
     CDS             4228..6063
                     /gene="walK"
                     /locus_tag="L1V38_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBN1316682.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6060..7376
                     /locus_tag="L1V38_002144"
     CDS             6060..7376
                     /locus_tag="L1V38_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316683.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQEN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7377..8246
                     /locus_tag="L1V38_002145"
     CDS             7377..8246
                     /locus_tag="L1V38_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBN1316684.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8301..9110
                     /locus_tag="L1V38_002146"
     CDS             8301..9110
                     /locus_tag="L1V38_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1316685.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9213..9842)
                     /locus_tag="L1V38_002147"
     CDS             complement(9213..9842)
                     /locus_tag="L1V38_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBN1316686.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10012..11304
                     /locus_tag="L1V38_002148"
     CDS             10012..11304
                     /locus_tag="L1V38_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1316687.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11380..12042)
                     /locus_tag="L1V38_002149"
     CDS             complement(11380..12042)
                     /locus_tag="L1V38_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1316688.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12267..12551
                     /gene="groES"
                     /locus_tag="L1V38_002150"
     CDS             12267..12551
                     /gene="groES"
                     /locus_tag="L1V38_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBN1316689.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12602..14227
                     /gene="groL"
                     /locus_tag="L1V38_002151"
     CDS             12602..14227
                     /gene="groL"
                     /locus_tag="L1V38_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBN1316690.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4916 a         2456 c         3070 g         4088 t
ORIGIN      
        1 ccattattat ctagtctagt ccattctttt tgtttgcagt atttgtgatg gctttccgta
       61 cccttagctc agttggtcag agcagacggc tcataaccgt ccggtcgtac ttctcgtaat
      121 ccaggaaggc cgtcagctcc gtccgcagta gcgtgtttac ggccagctcc agatgggagc
      181 ggaataactc gttcaaatca cctttggtgg ctagagtctg caggagttct gtaataaaat
      241 cgttcatagg gaagtcctct tttctgtgaa tgggtgtggt aactttattc tacagaaggg
      301 acttcctttt ttctatttac acaaaatatt ttatactctc aaatgtttgt atgcagttac
      361 atctgacttt attcgaatta aggaaaagat ttataaaaat aaaataaaaa aatatatatt
      421 taaattgact tattgtgaaa tcattaacta taattagttc agtttatgtt aaggagaatg
      481 atgatatgaa taagaaaatt gtagtaagtg gattaattat aggtggatta gtgttagcag
      541 ggatcgcagg gaaaaacttt gccgatgaca ttttgttatg gggtggagaa gataatattg
      601 aacaaatcaa tcataatttg gagtcattag ataaagcact agaaaataaa gagcaaaata
      661 ttagtagttt aaattcacga ttatcttcaa ataatcaaga acttgagcaa gcaaaggcta
      721 acgttgaaga atataaacaa aaagtgttga ctttggaaaa tgataaaaat caattaacta
      781 tagagaaaac aaatttagag aatcaattat caggaaaaaa tgctgaattg caaggtaaac
      841 aaaatgaaat caatgctaaa attgatgaaa taaatcaaaa aatagctgaa ataaatcaat
      901 taaacactga ttggaataat cgtttacaaa cagaacaaaa taaatttaat gatgctcaaa
      961 atactgttaa tagtttaaat caacaaatta atcaattgtc aaatgaaaaa aatactatta
     1021 aaaaccaatt gcaaagtact gaacaaaaac tagaaaaagc gcaatcagaa aacagtaatt
     1081 tgaataatta tattgaaaaa ctggaaaaag ccaaaagcga tgtagaagac acagcaaaca
     1141 gatcacaaga aatcgtgact gaacatacag gaaaatagat gcatttttta gtttaaattt
     1201 ctttaacaaa atagtatttt gttgctaaat aatttttatt tgaatattct acaatgatat
     1261 ctcccctcaa aatggagggg aagtacatac tgtgataatc tacaggttta ttgactgatt
     1321 aggatgttat taaaaaataa aatactaaaa tgcatacccg aatttcatac ccgaaaaata
     1381 aaaaatgcca ccacgtacac tcttttcgaa actacctaag tagccaagaa tgtactggtg
     1441 acgtgggttt ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga
     1501 gtcagctgct ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca
     1561 ctaagaattt taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt
     1621 ataggaaatc attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa
     1681 caaagttctt gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc
     1741 gtctccccgg cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt
     1801 tttttgtttt catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg
     1861 tttatcataa gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa
     1921 aatgcgtcag caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg
     1981 ggaagaactc cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta
     2041 tctttcacct gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa
     2101 ttacgttaaa ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt
     2161 agcattttta cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga
     2221 agggatattg ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga
     2281 tgaacaagaa gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca
     2341 aaaattcgac caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt
     2401 tgcaatgaaa cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga
     2461 gaaaacaaat gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag
     2521 aagaattgat aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc
     2581 aggtatatac agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg
     2641 aaatccctgg tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca
     2701 aaaaagacgg ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat
     2761 ataatgtggt tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata
     2821 cgaaaaatat tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag
     2881 aaggagtaga atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag
     2941 ttttctttaa tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg
     3001 cttctattgt aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga
     3061 tttattacac agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt
     3121 acgtcaaaga aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg
     3181 cgaaagaaga agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc
     3241 aaatctactt tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg
     3301 gtgtcggtgt acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc
     3361 agtgttttcc ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat
     3421 tttaattttc tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat
     3481 gagaaggtat gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg
     3541 atgatgagaa gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg
     3601 tttatactgc atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt
     3661 tgattttact tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac
     3721 gcaaaactta tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag
     3781 tcctaggctt agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat
     3841 tagttgcacg tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag
     3901 aggcagcacc tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg
     3961 tgacgaaacg aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact
     4021 tggcgaagca ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt
     4081 atgattattt tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga
     4141 tcgaagataa tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt
     4201 tgcgtaaccc agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc
     4261 aattttaaga tcgctattac ctttattctg attttattga tctcgatcga aattattggt
     4321 gcctacttta tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat
     4381 caaacggtgg aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca
     4441 gatgatgaag aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat
     4501 atcatcgaaa tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat
     4561 gaacaaagcg ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa
     4621 cgttatgttg ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg
     4681 tccccgaccg gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa
     4741 tattcggaaa tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt
     4801 atttcaatga tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg
     4861 agagaacaag ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga
     4921 caagatgaac ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa
     4981 gctcaagata caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca
     5041 gacggcgtca ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt
     5101 tccttgctag atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat
     5161 atcgaagaag aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac
     5221 cgttcaacca gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc
     5281 cgtcgcgaat caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa
     5341 gaaaaaacag aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca
     5401 ccgttgacaa gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag
     5461 gaagtagcac caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg
     5521 atcaatgacc tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa
     5581 tatgtcaatt tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga
     5641 aatcaggaaa aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa
     5701 gtagatacag ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat
     5761 tcaccagatg ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta
     5821 agtatcaccg atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg
     5881 ttctatcgag tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct
     5941 atttctagag aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga
     6001 aaagggtcga ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa
     6061 tgagaatctc tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat
     6121 acttctctta tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga
     6181 caaacactca aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc
     6241 ttcatgttac atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt
     6301 accgattgca attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag
     6361 gagacaaatc acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata
     6421 atgcgccttt tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga
     6481 acttggcaaa agaaagcgaa aatatgtatt ttactagaat acaattcgat caagaaaata
     6541 aaaaaatccg atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga
     6601 attggacaga tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa
     6661 cagaaccatc gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt
     6721 atagttatat cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac
     6781 cagatagcgt gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa
     6841 caatgtctat ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa
     6901 aagaaaatgc tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt
     6961 tagggaacct cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg
     7021 aaggcttccc ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg
     7081 aaacgaatgg ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga
     7141 taccttcaga cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag
     7201 ctaagggagc agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg
     7261 tcaaagaaac gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata
     7321 actggtattc agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg
     7381 atttcaaaaa aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat
     7441 tcagcagtta tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg
     7501 aatcaatcca acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg
     7561 agaacaagca aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga
     7621 attatcgcaa ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg
     7681 ttttgacgaa atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa
     7741 ttagtagttc cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt
     7801 atgtgtacac gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc
     7861 aagagtatga aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa
     7921 aaaacgataa tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc
     7981 agctgcgcga aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca
     8041 ataacaaaat accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc
     8101 tgaaagtccg ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg
     8161 ataaagtggt ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata
     8221 ctgtaccaaa agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta
     8281 agaagggaag taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag
     8341 caagtggaag ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg
     8401 atgcaggact tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg
     8461 accaattaga tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg
     8521 tcttggctcg taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg
     8581 aaccactgat tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca
     8641 gaacattcgg cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc
     8701 aattttatcg tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt
     8761 gcagtgatta tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc
     8821 atgatcttga gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag
     8881 gagatagagg acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta
     8941 atcggaccaa acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg
     9001 ctcatttaac aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg
     9061 aaatctatga tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat
     9121 caataaaaat ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt
     9181 tattttttta gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc
     9241 ttttcatgtt tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg
     9301 atcgtactgt cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct
     9361 gtacgtttgc catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt
     9421 ttagattgtt tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt
     9481 gcatttttag gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa
     9541 gaggcacccc caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg
     9601 gacaaagaag tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca
     9661 acatcaaaag atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga
     9721 acatctgatg gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac
     9781 aatgcttcgt ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc
     9841 ataaaaaacc tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag
     9901 aatccgattt ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata
     9961 gttaaattaa gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag
    10021 tggttagatc gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact
    10081 gctttgcgta atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc
    10141 ttatttgctc attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct
    10201 atgtatttta cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt
    10261 gccattgcat acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca
    10321 gccttgtctg cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg
    10381 acaggtgctg aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat
    10441 gcacgtttag taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt
    10501 tggcagtctt ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt
    10561 tcagcggttt ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc
    10621 cagcttccca ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt
    10681 gttccgtttt tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt
    10741 cccgtcttgc aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg
    10801 acggtggcaa atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt
    10861 acgggtgctg gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag
    10921 aaatacagag aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca
    10981 attatttttt ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca
    11041 ccggtcgttt caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt
    11101 acagcagtcc aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga
    11161 gtgcctgcag cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca
    11221 tttttgaaaa aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga
    11281 gcagcagaaa agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa
    11341 atcaccaatc taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac
    11401 agctaattga acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca
    11461 gatccgacca gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag
    11521 cagatgacca tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca
    11581 aaaatttgaa tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat
    11641 gatgggtcca gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat
    11701 gatattttgt gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac
    11761 agcgatgctt tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt
    11821 tggagcagaa gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata
    11881 aaaaatagct aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc
    11941 agacgtagat tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc
    12001 atagcaaaaa atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag
    12061 ggataacaag catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa
    12121 taagcagctg tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga
    12181 gaatgagtat tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa
    12241 aaaaagagtt atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg
    12301 aagtcgcaaa agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag
    12361 agaaacccca aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg
    12421 aaaaagttcc tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta
    12481 cagaagtaaa atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga
    12541 ttgttgagta aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat
    12601 catggcaaaa gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga
    12661 taaattagca gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga
    12721 aaaatcttac ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga
    12781 attagaagat cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac
    12841 aaatgatatt gcaggagacg gtacaacgac agcaactgtt ctgacacaag caatcgttcg
    12901 cgaaggttta aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga
    12961 attggcaaca aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa
    13021 agaagccatt gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat
    13081 tgctgatgca atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg
    13141 gatcgaaaca gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca
    13201 atatatggta acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat
    13261 cacagacaaa aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca
    13321 acaatcacgt ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct
    13381 tgtattgaac aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg
    13441 cgatcgtcgt aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac
    13501 tgacgatcta ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa
    13561 agttgttgta gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat
    13621 cgaagctcgt gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg
    13681 cgaaaaatta caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg
    13741 tgcagctact gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc
    13801 tacacgtgcc gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt
    13861 tatcagcaaa gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt
    13921 tgttcgtgct ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc
    13981 agtgattgtt gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg
    14041 agaatgggta aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc
    14101 cttgcaaaat gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga
    14161 taaaccagaa ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat
    14221 gatgtaagaa aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa
    14281 gaggctggaa cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt
    14341 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat
    14401 acgtgtttag agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt
    14461 gtaattataa tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa
    14521 tatccattca
//
LOCUS       DAFLWZ010000065        14493 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000065 DAFLWZ010000000
VERSION     DAFLWZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.065"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(27..602)
                     /locus_tag="L1V38_002152"
     CDS             complement(27..602)
                     /locus_tag="L1V38_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1316691.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="L1V38_002153"
     CDS             complement(607..1581)
                     /locus_tag="L1V38_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBN1316692.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="L1V38_002154"
     CDS             1864..2832
                     /locus_tag="L1V38_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1316693.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWG
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="L1V38_002155"
     CDS             2929..3222
                     /locus_tag="L1V38_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1316694.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="L1V38_002156"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="L1V38_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBN1316695.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3679..4434
                     /locus_tag="L1V38_002157"
     CDS             3679..4434
                     /locus_tag="L1V38_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1316696.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="L1V38_002158"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="L1V38_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBN1316697.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="L1V38_002159"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="L1V38_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBN1316698.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="L1V38_002160"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="L1V38_002160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBN1316699.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAMEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="L1V38_002161"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="L1V38_002161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBN1316700.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="L1V38_002162"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="L1V38_002162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBN1316701.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="L1V38_002163"
     CDS             9171..9713
                     /locus_tag="L1V38_002163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBN1316702.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /locus_tag="L1V38_002164"
     CDS             9736..11292
                     /locus_tag="L1V38_002164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBN1316703.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="L1V38_002165"
     CDS             11306..12208
                     /locus_tag="L1V38_002165"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBN1316704.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="L1V38_002166"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="L1V38_002166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBN1316705.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="L1V38_002167"
     CDS             13651..14073
                     /locus_tag="L1V38_002167"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBN1316706.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4784 a         2609 c         3117 g         3983 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatggggca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatggaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tat
//
LOCUS       DAFLWZ010000066        14256 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000066 DAFLWZ010000000
VERSION     DAFLWZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.066"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(51..3725)
                     /gene="rpoC"
                     /locus_tag="L1V38_002168"
     CDS             complement(51..3725)
                     /gene="rpoC"
                     /locus_tag="L1V38_002168"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBN1316707.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="L1V38_002169"
     CDS             complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="L1V38_002169"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1316708.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8128..9096
                     /locus_tag="L1V38_002170"
     CDS             8128..9096
                     /locus_tag="L1V38_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1316709.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9114..10019
                     /locus_tag="L1V38_002171"
     CDS             9114..10019
                     /locus_tag="L1V38_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316710.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10016..10822
                     /locus_tag="L1V38_002172"
     CDS             10016..10822
                     /locus_tag="L1V38_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1316711.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10958..11947
                     /locus_tag="L1V38_002173"
     CDS             10958..11947
                     /locus_tag="L1V38_002173"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBN1316712.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12264..12788)
                     /locus_tag="L1V38_002174"
     CDS             complement(12264..12788)
                     /locus_tag="L1V38_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBN1316713.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13075..>14256
                     /gene="scm"
                     /locus_tag="L1V38_002175"
     CDS             13075..>14256
                     /gene="scm"
                     /locus_tag="L1V38_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1316714.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SA"
BASE COUNT         4044 a         3081 c         2813 g         4318 t
ORIGIN      
        1 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
       61 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
      121 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
      181 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
      241 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
      301 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
      361 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
      421 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
      481 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
      541 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
      601 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
      661 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
      721 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
      781 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
      841 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
      901 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
      961 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
     1021 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
     1081 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
     1141 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
     1201 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
     1261 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
     1321 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
     1381 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
     1441 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
     1501 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
     1561 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
     1621 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
     1681 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
     1741 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
     1801 tctgttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
     1861 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
     1921 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
     1981 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
     2041 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
     2101 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
     2161 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
     2221 atatcttggg aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
     2281 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
     2341 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
     2401 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
     2461 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
     2521 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
     2581 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
     2641 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
     2701 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
     2761 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
     2821 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
     2881 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
     2941 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
     3001 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
     3061 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
     3121 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
     3181 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
     3241 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
     3301 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
     3361 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
     3421 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
     3481 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
     3541 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
     3601 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
     3661 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
     3721 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
     3781 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
     3841 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
     3901 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
     3961 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
     4021 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
     4081 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
     4141 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
     4201 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
     4261 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
     4321 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
     4381 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
     4441 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
     4501 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
     4561 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
     4621 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
     4681 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
     4741 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
     4801 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
     4861 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
     4921 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
     4981 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
     5041 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
     5101 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
     5161 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
     5221 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
     5281 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
     5341 tcaacgacac cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
     5401 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
     5461 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
     5581 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
     5641 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
     5701 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
     5761 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
     5821 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
     5881 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt
     5941 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
     6001 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
     6061 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
     6121 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
     6181 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
     6241 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
     6301 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
     6361 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
     6421 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
     6481 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
     6541 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
     6601 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
     6661 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
     6721 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
     6781 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
     6841 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
     6901 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
     6961 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
     7021 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
     7081 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
     7141 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
     7201 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
     7261 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
     7321 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
     7381 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
     7441 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
     7501 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
     7561 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
     7621 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
     7681 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
     7741 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
     7801 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
     7861 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
     7921 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
     7981 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
     8041 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
     8101 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
     8161 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
     8221 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
     8281 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
     8341 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
     8401 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
     8461 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
     8521 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
     8581 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
     8641 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
     8701 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
     8761 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
     8821 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
     8881 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
     8941 ggtaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
     9001 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
     9061 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
     9121 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
     9181 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
     9241 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
     9301 cttgtcttct aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca
     9361 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
     9421 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
     9481 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
     9541 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
     9601 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
     9661 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
     9721 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
     9781 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
     9841 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
     9901 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
     9961 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    10021 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    10081 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    10141 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    10201 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    10261 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    10321 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    10381 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    10441 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    10501 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    10561 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    10621 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    10681 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    10741 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    10801 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    10861 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    10921 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    10981 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    11041 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    11101 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    11161 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    11221 acaaacgatg ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg
    11281 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    11341 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    11401 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    11461 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    11521 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    11581 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    11641 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    11701 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    11761 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    11821 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    11881 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    11941 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    12001 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    12061 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    12121 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    12181 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    12241 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    12301 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    12361 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    12421 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    12481 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    12541 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    12601 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    12661 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    12721 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    12781 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    12841 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    12901 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    12961 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    13021 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    13081 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    13141 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    13201 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    13261 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    13321 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    13381 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    13441 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    13501 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    13561 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    13621 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    13681 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    13741 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    13801 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    13861 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    13921 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    13981 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    14041 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    14101 acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat
    14161 actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact
    14221 acctctacca caagtgatag cacggacaca tcagct
//
LOCUS       DAFLWZ010000067        14130 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000067 DAFLWZ010000000
VERSION     DAFLWZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.067"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..244)
                     /locus_tag="L1V38_002176"
     CDS             complement(<1..244)
                     /locus_tag="L1V38_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1316715.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="L1V38_002177"
     CDS             complement(237..1829)
                     /locus_tag="L1V38_002177"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBN1316716.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2339..3064)
                     /locus_tag="L1V38_002178"
     CDS             complement(2339..3064)
                     /locus_tag="L1V38_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316717.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3218..3544)
                     /locus_tag="L1V38_002179"
     CDS             complement(3218..3544)
                     /locus_tag="L1V38_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316718.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3581..3946)
                     /locus_tag="L1V38_002180"
     CDS             complement(3581..3946)
                     /locus_tag="L1V38_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBN1316719.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3983..4198)
                     /locus_tag="L1V38_002181"
     CDS             complement(3983..4198)
                     /locus_tag="L1V38_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316720.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4327..4662
                     /locus_tag="L1V38_002182"
     CDS             4327..4662
                     /locus_tag="L1V38_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316721.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4738..6735)
                     /locus_tag="L1V38_002183"
     CDS             complement(4738..6735)
                     /locus_tag="L1V38_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316722.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6833..7108)
                     /locus_tag="L1V38_002184"
     CDS             complement(6833..7108)
                     /locus_tag="L1V38_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316723.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7340..8074
                     /locus_tag="L1V38_002185"
     CDS             7340..8074
                     /locus_tag="L1V38_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316724.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8113..9255
                     /locus_tag="L1V38_002186"
     CDS             8113..9255
                     /locus_tag="L1V38_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1316725.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(9883..10368)
                     /locus_tag="L1V38_002187"
     CDS             complement(9883..10368)
                     /locus_tag="L1V38_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBN1316726.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(10370..11134)
                     /locus_tag="L1V38_002188"
                     /pseudo
     CDS             complement(10370..11134)
                     /locus_tag="L1V38_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11304..12497)
                     /locus_tag="L1V38_002189"
     CDS             complement(11304..12497)
                     /locus_tag="L1V38_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1316727.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12581..12781)
                     /locus_tag="L1V38_002190"
     CDS             complement(12581..12781)
                     /locus_tag="L1V38_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1316728.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(13205..13438)
                     /locus_tag="L1V38_002191"
     CDS             complement(13205..13438)
                     /locus_tag="L1V38_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316729.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(13445..13876)
                     /locus_tag="L1V38_002192"
     CDS             complement(13445..13876)
                     /locus_tag="L1V38_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1316730.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4295 a         2895 c         2270 g         4670 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat tctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacatat gattttttca taaaaaaaca gtactgtcta gtagtataaa
     2101 atatacaaat ttcttaaaaa ttttttcact aaaatcacta cctgaaacag tctaaaacac
     2161 ttatatatca acgtttaatg aaactatctc cgtttcattt cagatacaaa taaatatagt
     2221 cgggctccaa atccgaaaaa aaataccccc agtagcttat cctaagctac tggagatgta
     2281 taagtacggt catataacaa cggggtaggg taaataaatg aaaaagatgg aagaatcatt
     2341 attcaataac ttttttaaat acttcgttgt aatcagttac ctgtccgttc ttaaatacca
     2401 cagaataatc ttttttccca ttttcaagta accgaagtgg aatatcttta ccaactttct
     2461 ctgtcactgc attactgata cctgttagat tagctaataa atctgataaa gattgagcat
     2521 ctgtagaaat ctctgtatca gtatttatcg tgattccttt atcttcattt acaagtttcc
     2581 aagtaggtgg tatagctgtg tatgtttcta caaatgaatt aagtttttca ttaagtgact
     2641 tctcttttat atttccatct aaaaactctg tatatatggc ttgagctata ctaaaacaaa
     2701 gctggccttg ttctaataat tttacatcat tagttagtaa agctgtgttc acgttatcaa
     2761 tcgcttcaag aagagtatct ttggtgtccc taacagcttt aggtgtgcct tctggaattt
     2821 ccctacttga tacctcgtcc attttatctt ccataaaccc cttaaaatca tatctttctc
     2881 ccaaatccat agaagttttt gagaaagctt tcatttctga gtctatttct tcaataatat
     2941 ttaacatgtc tgatacatat tgtttaggct gattcgtttt taatctatat gtggtaaata
     3001 tctcaattcc tccaattatc aataaaattg ccaaacaaat ccataataat tttttctttt
     3061 tcatttttcc tcctatacac tgctgttata acagtgacta atgtaaagat tttcccagca
     3121 atcatcagac tattatttac agggaatcaa aaaaactcct tagtaagctt acacctttag
     3181 gagttcctgt ttgaacggta tgcataatac atttaaatca atttaacatt aacacctcag
     3241 tatatggtat ctctacatat acacggtctt tttttggata gtactcgaca tttatattga
     3301 tagcacttcc attgtctaac gtagctttag cccggtacgt gttatcacca ttatcatgag
     3361 tgatcgtcac atcatcacat gtccgattta agttatactg ttcttgtaaa atctgagtta
     3421 ccaatggtac agatgacttc tctagtccag atgaacccgt cattcttgaa aaaattatac
     3481 ctataatagc caatacaacg atacctataa tgacaaactt cttattcata tttactttat
     3541 tcaacttttt atctcctatc tccaaaatga ttttctctca tcagtaactc attgacatcc
     3601 ccaatagtac accaaagatg gctccagcta cccctgctat catcaaaatc gtacccattt
     3661 gttcatcttt ctctcgatat aagtaaccca taataacagc aacagcacca aataccacag
     3721 gaataaatgc taatgatact accatagaaa tccaaccaat aatcaaatac agcttccctg
     3781 tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct
     3841 ttactgtgtc tgttccggtt gtctcatctg tttcttgtaa tgctccgcaa aactggcaat
     3901 acttactttc atttgttatt tctttaccac attttctaca atacatgtct tctcctccta
     3961 aaatcattca attgcttatt agctaactgt ttactttatt aaatacatca gaaaacagct
     4021 catttattgg tacacttaat atctcagaaa gcattttcat ttgatagggt ttaggaatcg
     4081 ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt ttggctaact
     4141 cagtttggga aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga
     4201 ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca taaaatatat
     4261 aaatacttca aatgtcatta caaatacaac aacttgttgt actctactga gaaggggggt
     4321 gtattaatga aacagaagca atatgcaaag gtcattagag aaaagcgaaa agcactcggg
     4381 tggacacaaa aagaattagc taaaaaaatc ttctctacac aacaggcagt agcaagatgg
     4441 gaaaattctg taacagaacc taacctcgat agcttaacag ctctttctag agccctagga
     4501 acccctgtaa gccattttct agacaatgtt gacatagatt atgaggaaga gtttttggct
     4561 ctctatcgct ctcttagtac tgaagatgca attcgaacaa ttgactatat gaagctatta
     4621 aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt gaaaaataaa taacccaccg
     4681 aactttaacg gtgggtgtat tgagatgaaa taagattaag agctatggat aacctgtcta
     4741 gtttaatata attgggtctc ttctattcct tactctccgt ccatcatctc ttgttacact
     4801 tgtaaattga taaataggaa ctaattcaac tcctgataat atcaattctt ttattacttc
     4861 atctatccct gcccctttcg ctagatatac taaaaaacta ctgcttgctt tcacattgta
     4921 tagtttctta atatccttag aagctcgttc aagagtgaat ccttgtttaa caaagtagcc
     4981 tctgttttct attaaagcat ttttcacgct gttatccctg acatttcgta ggcgttcaca
     5041 aacagtgtta ataagttctt tttctgtcat tagatatgtc ccttgccacg ataagccctg
     5101 taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc ttgctaagtt ctgatcggga
     5161 attttgagga aatactcttt tagcctcttt ttcgttaaaa catatcttaa cccattcata
     5221 agaaaaatat tgatatgtaa aatgaaattt ttccagaagt ggaaggatat cttcattcaa
     5281 tttttgaatc acagaagttg cattaaaaac gtctaatcga tagacattgc ttctcttatg
     5341 tttaaagttt cctaacgctt tctcttcctt taacctattt aggtattcga gcatcttcaa
     5401 aggaacatct tcatcatcta atttttttat caatcctata aaagtcataa gtgatagtaa
     5461 cttattacat ttatctatgt cataagtttt accatagtaa gaactcattt ttttagctaa
     5521 ttgttccccc gacaaaatac aagtcacact ttccttacta tcatcaaaaa aattaacatc
     5581 agaaagcaag acatcataga cacgtcgcat ttcctctaga taattcctta ttgtcctgaa
     5641 aagtttgtct ttcattgatt caagagtgtc aaaaagtact tttgattcct ctttcaattt
     5701 tcgaaaatgt gtaggataca agtctaggtt ctctaatagc caattaaatg tttctacccg
     5761 actgtctttc tttaaaatta gcatcacaac tccaataaaa ttttcactga tatcacaatt
     5821 actggaatga caataaaaaa tggaatgccc agttttactg gtaaaaatac tagcagaggg
     5881 attatgatcg ttgtgaaaca gacatcttaa gtttttactt gacttaagta atttattcat
     5941 atcaatggtt aacaatcttt cataaatctc attaaaagac atgtcggagg aatcaaacag
     6001 gcagtcttta aaccactgtt tcatttcttc tttgtcgtca ttttttatca acttaacaaa
     6061 atcggtttca ttgactagtt catactctct ccctgaatca ctttgacaat ttttagaaca
     6121 tgtcatggta aaatcaatcg gaagctcagt aatatctaac atgttgtctt cattaattat
     6181 tatcactgca tctgacttat atcctccaaa aaacattcta ttcgaagcat ttacattgtc
     6241 atcacacccg gggatgttct ttttcaagta ttcgtaaaca gcaaccattt taccatagtc
     6301 agtaattgct tcttttaata gaaagacaat cttgtatttt tctagatttt cagagtaccg
     6361 aatacttttt tgtatcgcaa acgcagaatt atgaactaaa ttgatagata aaaccttttc
     6421 tatgcttaag tatctactat catctttact caaatctact accttcccct tctcatcttt
     6481 aacagtgtta tcgacatcca gaataattac tctggtttcc acaaaactct ccttgtcatt
     6541 gcctttattc tttgtcttgc ttggaataaa tgattgtgat gaatttagta tctctacaaa
     6601 ctcatctctt gtaacttctc tatagttatc taaacaccta tctcttacat cagttttttc
     6661 tttttttgta actggcttct ctaataattt ttctttatct acataaattg gaatattaat
     6721 cattgatgtt tccatttgtg tttcctcctt ataaaattct gttaaagact aaaacataca
     6781 gataataaaa acaaactctt tattactata tgttttagtc ttatttgttt actcaacctt
     6841 tataccgttc catgaaacta tcaatatcag attttttaaa tctaatgacc gtatcaattt
     6901 ttataacagg taacccgtat tgagaaacat attttctaat cgttcctact gatacaccta
     6961 gatattcact tgcctgctga tagtccatat actctagagt gactccagaa ataatgtctt
     7021 ctagcatagg ctttagcact gtaattatct ctttcacttg ttgttcaact tgtatagaaa
     7081 caatgctatc aatgatttgt agagacatat ttccccctcc tttcgtgatt gcttgaacaa
     7141 attttctaag aattatcttc gtattttttg ctcaaaataa aagtattttg ttattaaccg
     7201 attaatcaaa caaaaaatga ttaccagttc atcgacatac acataatacc tcgataaaaa
     7261 aggggtgtca atagttttgt aaaatttatt tacaacaccc cttttttgag gtatactaat
     7321 tttaggaggt gtggtcaata tgataaaacg tccaccaata aattatttag aacgaaaaaa
     7381 gatactcgga acaaaaataa aagctataag aaagagtaaa aaattaacac aaccagcatt
     7441 tggtcttatg attaacaacg gtcaattaat tgacaaaaag actatctacg aatgggagaa
     7501 gggaacctat ttaccaatac cagagcgatt atcccgaatt gctgatttgg gaaatatgag
     7561 tatagaggag ttagtttgtg gcaatgtaga agaatatatt ttgggaatta ttctttatag
     7621 agatagcatt gtactagatg gtataacatt tccagataaa aacctgttcc agcatcttcg
     7681 tcaacagttc ccaccagtac actctaattt agatacatgg ctggatagat attccaaatt
     7741 agaaccagag atgcaagaat ttattgctaa caagacttgt aataaagtta aaaatgaaaa
     7801 aattagtctt ttcaatatct taaaaataga agaattattc atcaatgcta ttgtagaaga
     7861 atttgacaat aacattcttt tcctcactag cagtatagaa gaactactag aaagaatggt
     7921 agatgaatgg ctacctattc aattgaaaga catgtcttat cccgaagaag ctgtgagaga
     7981 aattactgat aatataaaca agctagaaca aacgatttca tcaattggga aaaaatacac
     8041 taagaaaaaa atgaagggag gtgataccat ctagtggtaa gtactccttg taaactaaga
     8101 ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg
     8161 atgtataaag gacacattgc caccgatcca cgaactggtg aaaaaataaa tactacgaga
     8221 agaggtttta gtagcaaaca agaagctcaa aaagattatg acgagtacag acatcaaata
     8281 ttatacggtg ttaaaaagaa agcacctgat atgacatttg aagacctgta taatgaatgg
     8341 ataactcatc agcgtaccag tgttaaagct tcaacaatcg caatctcagt aagatacgca
     8401 aataatcaaa tacttccagc atttggtaag cttaaactat cgaatatctc tgtcccatat
     8461 tgtcaaaaag tggtagatga atggcacagt aaatatgaaa gttacgatta tatgagaaaa
     8521 cagactgcac aaattttacg ctacggggtt gcaatgcaat atattgacaa taatcctatg
     8581 gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa
     8641 gaggagctta ataatttact ggatgctttt aaagattttg gtaacatgaa acaatacgcc
     8701 ttcttcagat tattggcata cacaggtatg agaaagagtg aagtactcgc tttacagtgg
     8761 aaagacatag acacgtttaa taaagaacta catgtcaata aaactcttgc tgtagatgaa
     8821 tttggtaaag ttataattca atctccgaaa acaagagctt ctagacgagt tatctcttta
     8881 gatactgaga ctctttctat cctcaacaac tggaaattac agcaaaaaga agagtattta
     8941 aaacttggat acaatactag ctctaaagag caacatgttt ttacaacagt taaaaacact
     9001 ctatacattc caaacactgt taatgattgg ttaagatata ttttgaaaaa atataacttg
     9061 cctcgtatta cacctcatgg gtttagacat acacatgcta gtttattatt agaagcagga
     9121 gaatctgtca aggtagttca acaacgatta gggcatgaaa atagtaaagt gacattagac
     9181 atctatgcac atattacaaa taatgcacct aagaaaacag gtcaagactt tgctgatatg
     9241 atggctcatc agtaaaagag ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca
     9301 aaaaagctag aacccttata tatcaagggt tctagctcct ataacaggtt tacccaacac
     9361 tgccttccaa tgactctttt gggaatcaga ggaaagaatc aggctttata gagatatttc
     9421 atctaacaaa ttactttaga ctgacagtat atatcagcag gtactgtcat cgggaacgta
     9481 gccaatatcg tatccaaaac agcaggtaga gaagctattt gaggattcaa gttattctat
     9541 ttcaaccatg aagttaagtt cattaaaaat aaagatagtt ggtatttcaa taatttttgt
     9601 atagagttaa tcactttatt gatgctaatt catcttgatt ggtattataa tcgtattcaa
     9661 gttgcgtggc gtgcttttgc tagaaaatat ataactgttc tttataaaga aatataagga
     9721 ttaaacattt tttatcatag agttttactt atctatagaa ttatgtctgt tcctaattca
     9781 gtttgatgaa ttaactgata aaaaaatatc tactatttaa agatacaggg ataagtaagt
     9841 aaaaaaataa catgtcatta gatagtagac agttccaact ctttatttac cttttttgta
     9901 tgctgcactg tcaatccaag ttcctaaatt gttgtatcca tcatcactta tataatcata
     9961 ttggccatca ataatttcgt caaaccacaa atattctcca tctggttttt gcccaattat
    10021 tttaattact gattgactag tagttgtcat ctggttaaaa tcttttattt tacctatatt
    10081 aacggccaaa atagcatttc ctcgcttata actctcctgg atttcatatt taacatattc
    10141 tcgatcaaga gtttctttac ctatcagcac cacagtcact gatgttccaa ttaattgatt
    10201 atctatccag ttttttatag caatatctcc attacgttta actttctcaa attcagcctt
    10261 atctacaaaa ccagcttcct ttgttcctcg caaagtccag ctgtttctaa ctaccattgc
    10321 tcttgttaca tctgcataat ggaaactaaa aaaaaccctt ctcaccatat taatcctcct
    10381 gaatactatt tattaaactg acaatttgtt caactttttt atctacttct ccttcagtat
    10441 ctaatttttc tagcgcttga aatttacttt ttaaggaatc atcaaaataa tcactgaaat
    10501 tctcttgaat cttatcaaac aaaaccttac ttgcaccttt ggtaaatcca atcggaacta
    10561 ctatattttc attttgaaca gataattcaa attcttcaat cattccatct gctgtaacta
    10621 tttcacctga ttcaagtttg tttccaaaaa caaaaatact aatcccagac tctgcaataa
    10681 tgttttctcg atatcttctc cactcatgag gcatatcaag gggaagtggt cttaaagaaa
    10741 gtacgtcttg tatgttattt tttcttaaat ttcttctctg ctttagaact cctgaaacaa
    10801 tactattacc aattccaagt ccgtaacctg atactattct ataaccggat tcagaaagcc
    10861 tatatgctaa tttctcgaca aattttaatc ctttcgattc agatgtaaat ggagtataat
    10921 caacagcact tcccgaaata aaaatagttt ttctcaaata cttttttcta atacttttca
    10981 aaatatcagt aatctcagaa taatcatcta cttcaacaac gtttatcgaa aatctggaca
    11041 aatcattgat ttgtagtctt ctttttgtca gttcataatt atatctctct tgatcaaaaa
    11101 aatcctcaga atcgacaaaa ttttccttta aaattatatg ggattttaga ttatcttttt
    11161 agaagttctt gaatgtcggt atagcccgtg tttccgggct tttccggcat ttttgatatt
    11221 gttagatact tacaaatgtt cttattacct ctcaccattt ccccctcaaa agtagtaaat
    11281 ggagtagtaa aaccggcctt gtgtcaggct gccagccgtt ccatttctgc ccttgcggaa
    11341 tcgaatgtgg cgtgtgcata atagttcagc gtcatggtga tattggaatg tcccataatg
    11401 tactgcaagg ctttggggtt cattcccgca ttggctaacc gggtgcagaa tgtatgacgc
    11461 atagcatggg gcgtcgtcgt tttcggcaac gcttcttcat ggctcttgtt gtacttcttc
    11521 acaagcctgc caaacatccc gccataatct accgccgtca tgggatagcc gttctgtttg
    11581 agaaacagga aattggcata cccgtcaata atgaacggct ttgcaccttt gcggtttttt
    11641 atcactcgct ggaacgcctg atacacttcc tcattcatgg ggatttttct gacgccgctt
    11701 tgggtcttgg gttcgtcaat atagtaaccg acgccggtat ttctcaaaag ctggtggctc
    11761 acgatgatta cccggttttc aaaatccaaa tctttgtccg tcagtccgca cagttccgaa
    11821 atgcgaagcc ctgtccccag cagaataacg attgcgtcat aatgcttttg gtaaacctta
    11881 tcaccttgaa taaaggacag aaaactttct tcctgtgctg gtgtaagagg cacctttggt
    11941 tccgtatcgt cgtccagaac gtcactaagc tggaagtcaa acgggttttt tcggatgcaa
    12001 tcgtcctgta tggcggtgta aaaagccgct ttcagggaac gcttgtcgtt attgatggtc
    12061 ttataagaaa ggcccttttc tttcatccga agcgcccatt cctttgcgtc ggacagcttc
    12121 acactgtcaa tcgggcagct ccccagccga tcttgttcca gaatacgcat cagccgttcc
    12181 cggcccagtt tggtgttgtg cttcacattg ccccggtgcc tgatctgctt ggcgtagagc
    12241 tggcagacgg tcattttctt gccgatggtg tctatcccgt cgtcaaggtc tttctggatt
    12301 tctttctcct tttcccggag tgaaatatcc tcccgtttac ctgccggggt cttatccgta
    12361 ggcactaact tccatgagta aacaaactgc ggttttccaa aggtatcaac atatttgtaa
    12421 gcatatcgtc cgtcttttct ctggctctct ccagaccgca aaacgcgatt tttgctgtct
    12481 cgtctttttt ctgacatctc gtcatgctcc tttccatgac ggaaagagcc gcatatatgc
    12541 ttataaatta ttataacata tctgcggccc tttttcacta ttagattgtg tccaaagtgt
    12601 caattatttt ctcaaactgc ttgcgtttga tctggatgcg gttgccattc ataatgaccc
    12661 agccagaggc cggattttcc tcggccagct tacgcaattt gttttctccg atacggaaat
    12721 atttagacgc ttcctcaatc gtcagcgtgt atttttccca aataggcaca tcatggttca
    12781 taatgcagcc ccctttcaca aattcaaagg tttgtgtgat ttaggggcat agacggacgg
    12841 ctgctggcac agctccacgg gactttcacc cccgcgtggt tctcacgcgg ccctacccat
    12901 tgcctgcgac gcttttaacg ctcggactgt ggctataagg gagtatcata gtcctgcctg
    12961 tacgtcgtcg cccgcaagcc gccacgctca cattgcggcg tggtgttcct cgctccgctt
    13021 ttcccgtagg gaaaagtatc atggcgcacc agccgtccgg ctcggcacag acagaatgtg
    13081 tccgtatgcc ctatgatgcg ccgccgttat cttgcgggca tatttatcaa ggtgcgatca
    13141 ggccaccggg aaaacaccga aacggggaaa gggtaagccg tttcatgctg ccggggccgg
    13201 ttcgtcagtt cgtgacgata gcgtggatga gcttgatttc cagacggcgc ttcatggcct
    13261 cgtccagaca cacatgcgga tagccgtttt cgtcatagag cgtccgggta cacagcttgt
    13321 tcatgtaacc gctgtaatac tgcaaaacgc gctctacggc tccggcatcc ccagcgcggg
    13381 cggcctcgat caccgaaagg ggcaaaagct caatgccctt gtagttcggg ttcttcatcc
    13441 gcgtctaacc tcccttcggc atcaacgcct ttagctgttt ccgcagctcc gataaggtat
    13501 ttgtcctgtg ccgctgaacg gcactccggg acattcccac aaggccgccg atctcaccat
    13561 ctgccatatc cagaacacag tgcaggatta aaatactctg ctccatgctg ggcagcgcgg
    13621 caaaggcttc ggcaacaagc tcattgttga tatgtaggtc atagccatgc gacgaaaacg
    13681 taaagctgtc gctggggtag tgatctactg tacagagctt gtccaaatct gcctgtgaca
    13741 aagagcttag tgacacttca cggtcacggc ggcgcttcat ttcagccaag tagcttttgg
    13801 cctcgttacg cagtaccgtc ttgcaaaaag catcgaacat gcaccgcgct tcatagtcgc
    13861 gggggatagc atccatcttc tcaccccctt tctgtggggg acttaggtgg ttctctccct
    13921 ttccgctaac aagactttga caaggccgcc agctacccgc taaatacctc ctttttgaaa
    13981 atttctcaaa aaattttttt ggggacagcc gggccgcaaa agacgacaaa aatcgcccgg
    14041 caggtcgcaa acctaccggg cgagaaaatg ctttgctatg ctgctgattt acatggtata
    14101 gtacatactc ataaccggaa tagccctgtg
//
LOCUS       DAFLWZ010000068        14107 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000068 DAFLWZ010000000
VERSION     DAFLWZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.068"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(5..829)
                     /locus_tag="L1V38_002193"
     CDS             complement(5..829)
                     /locus_tag="L1V38_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1316731.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(802..1482)
                     /locus_tag="L1V38_002194"
     CDS             complement(802..1482)
                     /locus_tag="L1V38_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1316732.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1505..2443)
                     /locus_tag="L1V38_002195"
     CDS             complement(1505..2443)
                     /locus_tag="L1V38_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1316733.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2688..3551)
                     /locus_tag="L1V38_002196"
     CDS             complement(2688..3551)
                     /locus_tag="L1V38_002196"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBN1316734.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(3693..6266)
                     /gene="mprF"
                     /locus_tag="L1V38_002197"
     CDS             complement(3693..6266)
                     /gene="mprF"
                     /locus_tag="L1V38_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1316735.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6407..7213
                     /gene="proC"
                     /locus_tag="L1V38_002198"
     CDS             6407..7213
                     /gene="proC"
                     /locus_tag="L1V38_002198"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBN1316736.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7292..8848)
                     /gene="rny"
                     /locus_tag="L1V38_002199"
     CDS             complement(7292..8848)
                     /gene="rny"
                     /locus_tag="L1V38_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBN1316737.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9259..10308)
                     /gene="recA"
                     /locus_tag="L1V38_002200"
     CDS             complement(9259..10308)
                     /gene="recA"
                     /locus_tag="L1V38_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBN1316738.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10417..11658)
                     /locus_tag="L1V38_002201"
     CDS             complement(10417..11658)
                     /locus_tag="L1V38_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBN1316739.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11898..12476)
                     /gene="pgsA"
                     /locus_tag="L1V38_002202"
     CDS             complement(11898..12476)
                     /gene="pgsA"
                     /locus_tag="L1V38_002202"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBN1316740.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12685..13608)
                     /locus_tag="L1V38_002203"
     CDS             complement(12685..13608)
                     /locus_tag="L1V38_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316741.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
BASE COUNT         4038 a         3145 c         2466 g         4458 t
ORIGIN      
        1 taatttagtt attttttctt ctgaaggcaa ccaatattcg tttgatgata tttacaatca
       61 ggaacaaagc aataaagact aatgtgattg ttgctcctgg aggtgtatct agataaaacg
      121 agctagttag tcctgacagc atccctagaa atcctacaca aacactgata gcaatcacga
      181 cattgaagct tttgcctaat cgcataccga ttgctgcggg aagaaccatg attgcggata
      241 tcaaaagtgc accggcaatc gggatcatca cagcaatagc cacaccagta atcacattga
      301 acatcatcga catcaaatga acgggtagcc catccacgtg ggcggtatct tcatcaaaag
      361 tcagaacata catcggccgt ttgaataaaa agaacaatat accgatggca acgaataaga
      421 ttcctaaaaa gatgacttgc tcccatgtaa tggtcacgat cgaaccaaac agataggatt
      481 ggatacttgt tgctgaattc cctccgctca aattcatcaa tactaacgct agcgccaaac
      541 caccagccat taaaatggca atggagattt ctgaataggt tcggtagatc gttcgcagat
      601 actccaatat cacagctgct aatacaacga ctagcatggt cgtaagtgta ggattaaggt
      661 tcaaaaagaa tcctaacgct acccctgcta aagagacatg agaaagcgta tcagccatca
      721 gcgattgtct tctgatcact aaaaacacac ctagcatcgg ggcgattccg gcaatgaaga
      781 tagcggcaag aaacgctctt ctcatgaatt catatgaaag caacgccatt gagaatcctc
      841 ctttctcacc agtcggatct gtctgtccgc atactgtttg atatcttcat gatcatgggt
      901 gatcattaga actgatttcc catggacatg cgcactatgt cggagaagac gataaaattc
      961 atttctggat tcttcatcca tacctgttgt tggttcatca agaacaaata agtcagggtc
     1021 agtagcaaaa atacgcgcta aactgattcg ctgcttttgt ccgccagaca attcacctat
     1081 tcgccgattt cgcatatccc acatccctac agcttctaaa gcacgctgta catgttgatg
     1141 atctttttca gagagacgct tgaaccagcg gcctcttgga tatcttcctg aacggactaa
     1201 ttcgatcacc gtactaggaa aacctgcatt gaaagatgca acttgttgag gaatataacc
     1261 gatacttaat ttttttcctt cttgattttt ctcagcaatc tttatcattc cttttgaagg
     1321 tttcagtaat cctaacgatg ctttcaccaa ggttgacttg gctgctccat tttctccagt
     1381 taaaatgaca aattcacccg catctacatg ataagagaca tcttctagta caggttcatc
     1441 atcatagtaa aaggtcaaat cagatatttc gatataacgc accttacaac ctccattcta
     1501 aaacttaatt gatactttct tttaaagctt tcagattttt ttccatgaca gaaatataat
     1561 tttcgcctgc tttgatttgt tcattagtca agctttctaa aggattcaac acttctagct
     1621 tcactcctgt ttcattcgac aatgtctcag ctaccttcga agaggcattt tcttcaaaat
     1681 aaatcacttt gatgttgttt ttcttcacaa attcttttag ctcagctaag cgacttggtg
     1741 tgggttcctg atctggtgaa acgcccgaaa tcgctacttg ttttaagtcg tattgattcg
     1801 ctaaataagc aaaagcagca tgctgagtga caaatgtgcg gtttgttgca tcttttagct
     1861 catcggagta tttttgatcc agtgcttcaa gctttttgat ataagcatcg gcattcttcg
     1921 taaaagtttc ctttttatct ggatattttt cgcctaattc ttcagcaatc gttctgactt
     1981 cttttatagc taataccgga tcgagccaaa catgtggatc gtattcatgt gaatgaccat
     2041 gcccttcttc tgattcttca tgttcgtctg cttcttgcga ttctaaacgg tcgattcctt
     2101 tagctgcttc gatcatcaag gtctgtttgc tatccactga atcctttaac gaatccacaa
     2161 aaaattccat gtctgaacta ttatacacga aaacatctgc atcggaaatt tctgctcttt
     2221 cttttgcact tggttcgaaa tcatgcggct ccgttccagc agggatcaaa agtttcacgt
     2281 ttccttcatc ccctacgatc tcttttgtaa aatcatacat cggataaaaa gtcgtaacga
     2341 tcgtcaaatc ctcttttttg tctgcttcct tgttcgtatt tccacatgct gcaaacagta
     2401 aagcacctat cattaccgta gctgtcaaaa gatatttttt catttatatg ctcctttcaa
     2461 tgaacaaatc ggaattttac gatttattaa cgtgaactaa tgtatcaaaa taaaaaaaca
     2521 cagtcaatag aaatccatca atttctgatt taagcatgta tattcttgat taaatcgtaa
     2581 aatggatgag ttgctgctca tatctagcca tttcactaca ataaaaaact gaagaatacc
     2641 attttaggat tcctcagttt ttcatcacct attttacttc ttatatttta ttgcagggtt
     2701 cgtactaaat aaacttcctc acaaaaacct tttaacccat tatatactct ctgcgctctt
     2761 gaataatgtt gacacaaggc aaaaacggtt ggtccgcttc cactcatcaa tgcagcatct
     2821 gctccgtact tgatcatacg ctctttgatt tgatggatga ctggatgccg ctttcccgtt
     2881 atatcttcta aactgtttcc catttttttg atcatctgct gataatcttg ctctcggatg
     2941 gcttcagcaa gtccgtggat gtcttgatgt tggatggctt gcgtatctac ttctctaaac
     3001 actgtacgtg tagagacact cattcttggt ttgaccaaca caacccagca ctgtggcata
     3061 gaaggtaata cttggatttc ttcccctttg ccaccgacaa atgccgtact tccgtagaca
     3121 cagtaaggaa catctgtacc gacttccaaa ccgatttctg ccagttcttc taacgaacag
     3181 cccagattcc ataattggtt gatccctctt agagcagctg cacagtctgt acttcctccg
     3241 cctaatccag ctgctactgg aatattcttc ttaacaaaga tcttgacacc ggttttgata
     3301 ttgtatttat tttttagcaa taaagcagct tgataaacat tgttccgttc atctaccggt
     3361 aaaaatgctt tatttgtttc tacaatgatt ttgtcttctg ttatttcttc aaaaaataga
     3421 tgatctgcca agtctacgct cgacatcacc atttccaact catgataccc atcttgccgt
     3481 ctatataata catccagtcc taaatttatc ttggctggcg ctttttcaat caattccatc
     3541 ctctcaccca ttcgaaaagt ctaagtcgca agtattctat catagggaaa aataaaagta
     3601 tagcttatgt ctgcctagtg gttgattttg tcatcgtttc aacagctttc acagaatttt
     3661 ctcttcataa tccaaacaag ttctagtgat tcttataatt ctgtgagcac ttcttctgcc
     3721 aaactcggaa catttccttt ttcttttcct atcagactga gtagctgcat ggtagcaaat
     3781 ccgaaattac ttcctttcct ataagcaaaa taacgtcctt cccaatgatc gacatatttt
     3841 aatttctttt cataagcaga ctggaaggaa tagaaaaaat taccataatt atatacgata
     3901 tgcatgactt tttcttgaaa gaaagaaaaa tctgtttctc caacattagc taatggagct
     3961 aagcctagat tggcttccga gtagcccatt ttctcgtata caataaacag attggctaac
     4021 agatagtcag ctaattcctc agattcttta ggtaagaccc gcaacaaatc atatcccgcc
     4081 tgcttcttcg tcatcggctg agcggtgatg aagccaacga ctttttgatc tttacggaca
     4141 ataccgacac cgctagataa tacatatgat ttatcaaatc gtcccacaga gaagtatttt
     4201 tctcgtgcac cttgaagcca tttttgtgaa acttcattta cagcttgatg taattcttcc
     4261 ggcagttgat cgtaccaagt aaaatggtat ccttctttca tcaaacgttg atattcaagt
     4321 tgctgactca gccgagacaa gtcttctgtt gctagatcaa caatccctgc ttcacctact
     4381 ttcgtgaagt gaaaacccaa ttcatgaagc atcactacgt agctttctga tatcttataa
     4441 aacgcaagct gatagcctaa acaatctgct tgtttcataa actgattcgt tgctgcccgc
     4501 atcattttag gattgccaac tggatctcct aaaacaaagc atttgtttcc tttgatctga
     4561 taaccaaaaa cgacttgatc ttggtcgtct tcttggtaat aaaaataact gtaacctgac
     4621 aagcgaagct gatggcttgt agctgtgcct ccgtatgttt ccaataaacg gtcaaaacgg
     4681 tctttttcgt actcactgcc aagcttcgta gtatcttcag ctaaatattg ataaagcgcc
     4741 actaaagcta gcaatgagat gcccaaacca ataagccctg agaaccacac atcatctgaa
     4801 ggaaacaaaa taaaatgatt tcctgttatt cgaccgacta aaaagcgtcc gctgtgatag
     4861 cctgcaattg cgtaaacgat aaacaaaaag ccgaacaagc tagcatcaaa gattatagct
     4921 ccccaagaat aaacgaattt tgttcgataa aattcttttc tggataacca cacagctaac
     4981 agaatcaaga catataccaa tatcaactgc caagataacg tacgtgtgat tgtatttaaa
     5041 ataccaaaag atagtaaagc aatcgtaggc agaaatgcct ttttgacttt tactgaaagt
     5101 gctctagcaa ggccgagtaa taaaaagcca accaatagat tcactgtctg atctaaaaaa
     5161 ttgaatgaga acggcaataa tacttgaaat agccgactga ttgcagacag attagtgatt
     5221 gttgatagaa gtaccatcat gatccccgca aaatagacag cacttacgag cacgatatgc
     5281 gcaacctttt ggaaaaacag tcgcggaatg ttatctaaaa atcgattgat tttgactcct
     5341 gtatgtgtga tgaacaatag aagtcccgtc ataaaaggta gaacataata aaacaaccga
     5401 taatataata gccaaactac tgctacatct tgccgaacag acaattgact cattcctaag
     5461 atcatcaaaa cgtcaaaagt ccccattcca cctgggacca tcgtcagcat tcctatcaat
     5521 gtagcaatca tgaacatagg atagatcgaa agcatcgaaa tatctattct catcaacttg
     5581 ccgatgatca aaaataccgc aagggctccc gtccattgtc caaaggatgc cagtagcaga
     5641 ccaagcaagc cttttggata aaactcgaag aacaatgtct ttctctttag ataagcaaaa
     5701 aagaaaatga ctggtgctaa aaaactaccg ccgaaaagcc agatccaata gcttcgaaaa
     5761 atactttctg actgaataaa aaagacatca ataaatgtaa gaaacgacca tacagacaaa
     5821 ccagtcagca taaatagtgc gacttttgat acagtggcta aaaccatttt tctatttgtc
     5881 tgctttccat aaaaactagc ccgcagactt gctcctacca caccaccaaa accggcgaga
     5941 ttgttgatcg tgtttgttac ccacgcagca agaagaaact cttttctttc catttttggt
     6001 tttccttgtt tttctaagac tctgatcgtc acccaatcat acaacaacat cggagtgaca
     6061 cccagcagtc cagccagaat catgagcagg atcgtcatgc ggctttgttg tcccatcctt
     6121 tgccaaatat cttgccaact catgccatta gcaatatttg cgacttgatt tgccacaaag
     6181 actaacacgg agccgaaaaa aatcagtttt aaaatcagac tatgttcctt tatccattgc
     6241 agcatcaagt atcgtttatt tttcacattt tcccattcct aacttgtata cttttgtgtc
     6301 ataccccaat gttatcttat ttattttaat ttttccactt tagacctgtt ctttgcttgc
     6361 gatgatagaa aaagaaagat atcctaatgc taaaggagag gataacatga aagtaggatt
     6421 tatcggcaca gggaatatgg cacaagctat tattgatggt ttattaaaaa aaggaacagt
     6481 ctcgaaagaa gaggtgttcg tttccagtgg acattttgaa aatgcacaaa aatttgctgc
     6541 tgaaactggc gtccatgcat gcaaaagtaa tcaggaagtt gcatcacaat cagatatcgt
     6601 tcttttagcc gtgaaaccaa aaatcattga aaaagtattg gaagaactaa gagaatatag
     6661 ccagaaagtc ttattcattt ctattgcttc aggaaaatca ttaatagatt tagaaacagc
     6721 gcttgaagat cctcaggcct ccatcgtacg tgtgatgccg aatgtcaatg tcagcgtagg
     6781 agcaggcgtt tctgcgattt gcaaaaatga agctgccacg gaggaacagc ttcagcaagc
     6841 tacgatgatt tttgaagcaa tcggcagcgt ctatccttta gcagaatcag atttcagtac
     6901 attcattggc cttgctggca gctcacccgc attcgtttac atgctgatcg atgcgatggg
     6961 acggactggt gtactgaatg gtttgtccaa acagacagcc actgagattg ctgcaaaagc
     7021 aattatgggt tcttgtcaaa aattcctttc aagtgataaa aatccatggg aacttgtaga
     7081 ccaagtttct tctcctggcg gtacaactgt tgcaggtgta gttgccttag aagaagcagg
     7141 attcatccca gcaatcatca aaggaatcaa tacgacgatc gagaaagatc ttgagatgtt
     7201 gaataaaaaa taatgatagc aatgtttttt cgtgccttac aaaaaaagaa gagctgtggc
     7261 ttttgccgcg gctcttcttt tgtatttttt attatttagc ataatcagtt gcacgagttt
     7321 cccgaataac gattactttg atgtgtccag gataatccag ttcttcttcg attcgtttac
     7381 gaatatcacg tactaaacga acagcgtcta aatccgagat ttcttctggc ttgaccatta
     7441 cccgaacttc gcgtccagct tgaactgcgt aacttgattc tacaccggcg aagctgttcg
     7501 aaatattttc cagacttctt aaacgacgga tgtagttttc taatgattca cttcgcgcac
     7561 caggtcttgc tgctgagagc gcatctgctg cagctacaag gacagagata acagaagtag
     7621 cttccacatc tccatgatga gaagcgatcg cgttgattac tactgggttt tctttgtact
     7681 tggcagctaa ttccgcaccg atctcaacgt gagatccttc aatctcatgg tcaagtgctt
     7741 tcccaatatc atggagcaac ccggcacgtt ttgctaattg gatatcttcg ccaagctctg
     7801 ctgctaagat accagctaat tttgcaacct cgaccgaatg cttcaagacg ttttgtccat
     7861 aactagttct gaatcgcaga cgtccgatga tcttgattag atctggatga agtgtatgag
     7921 caccgacttc aaacgctgcc tcttccccgt attcgcgaat acgttcatcc atttctttac
     7981 gagatttctc gaccatttct tcgatacgcg ctggatggat tcgtccatct tgtatcagtt
     8041 tttccaaggt catccgtgcg atttctcttc ggattggatc gaatccggaa agaacaactg
     8101 cttccggtgt atcatcgatg attaaatcga taccagtcag cgtctcaagc gttcgaatat
     8161 tacgaccttc tcgtccaatg atacgacctt tcatttcatc attcggaagg gtaacgactg
     8221 aaacagtcgt ttctgaaact tgatctgctg cgcagcgttg aatcgctaat gataataagt
     8281 ttttcgcttt gcgatctgct tcttctttgg cacgctgttc agattctttt accattagag
     8341 ttaactcatg attcagctct tcttcagtcg atttcatgat gacatctcgt gcgtcctctt
     8401 ttgataaacc agcaattttt tctagttctt tttgttgatc ttcaatcatt ttttcaacgt
     8461 ctttttctcg ctcttcaatt aattgctgtt ttgaactaag tgcttcttct ttactttcaa
     8521 gtgagttctc gcgtttttct aacgagtcat ctttacgatt cagcgtttgt tcgcgttgaa
     8581 tcaaacgatt ctcttgagat tttaattcta acttactttc tctcagctca ctttcaactt
     8641 cagaacggta tttctgattt tcttccttag cttctaacaa tgcttctttt tttagagttt
     8701 ctgcttcttt ttttgcacta tcgatgattc cagcagctga tgattgtgca ccagctattt
     8761 ctttctcgtg acgtgacttt gcgaccataa accctaaacc aagaccgaca attaaaccga
     8821 tgatagcgag gagaatgttg aataccataa aatccacctc catactatct ttttcatttt
     8881 tatcatctat acagcttcta tgataaatta ttctaaactc gtcaatatgc atcttcgcat
     8941 atatgtgtac aaaaaacatg cacaacttta ttctaatgtt tgtaccccgt agtgtcaact
     9001 ttaaataaac aaagaaacgg ctttctactt attcattaaa cgatggtttt taaaataaat
     9061 gacactagtt tcatataggt aaacctttaa attgagaaac ttttctatta aattattctt
     9121 tgtagatgaa cagatatttt tattttatgt acccactcgt ataattaaat aactcacgat
     9181 ttctttattc aataaaaaaa cggcaggtca aggagagtac ctactcttca gaccagccgt
     9241 ttttgtttat cataattttt attcttctac taaaggcaat tcttcttgtc ctttttcatc
     9301 ttctgggaca gcgacttctt caccaatacc ataagctgct ctaactagag cagaaacttc
     9361 tgccatcatt tcaggatgat tagccatata gattttagcg ttttcccgtc cttgaccaat
     9421 ccgatcttct ttataagaat accaagcacc gcttttatca acaatgtctt tttctactgc
     9481 catgtctaga agttctcctt cttgtgagat ccctaaacca tacatgacat ctacttcagc
     9541 gattttgaaa ggaggtgcta ctttgttttt tacgactttg atctttgtac ggttaccaac
     9601 aatatctgta ccttgtttca attgttctgc acgacgtact tccaaacgga tcgttgcgta
     9661 gaatttcaat gcgcgtcctc caggagtgat ttctggattc ccaaacatca cgcctacttt
     9721 ttcacggatt tggttgatga aaatagcgat tgtttttgtt ttgttgatcg aaccagagag
     9781 tttacgcaat gcttgagaca tcaaacgtgc ttgtaacccg acatgtgagt cacccatttc
     9841 gccgtcgatt tctgctcgtg gaactaaagc agcaactgaa tcgactacta cgatatctac
     9901 agccccactt gatactaaag catcagcgat ctctagacct tgttctcctg tgtcaggctg
     9961 tgaaagaagt agttcatcga tattcacacc taatttttgt gcatattgcg gatctaacgc
    10021 atgctcagca tcaatgaaag cggccgttcc gccatttttt tgtacttctg caatagcgtg
    10081 tagtgcaact gttgttttac ctgaactttc aggtccatat acttcgatga tacgtccacg
    10141 ggggtaaccg ccgacaccta aagcgacatc taacgcaaga gagccacttg gaattgtaga
    10201 gatttgttgg tcgatttttt cgcccaattt cataatagag cctttaccat agctcttttc
    10261 aatttttttc agtgcagcat ctaaggctgc tttacgatca tctgccaata cgataatcct
    10321 ccttatattt acaaatcaga gcaacatttc attatcctta tcatatcttt tttagtgaaa
    10381 aaaagcaaga aaaaaccgaa caaatattcg catttatcat tttcttaaaa gctgttttct
    10441 caaaagatca aatccttgca taaccgcatt atatctgata gcagcacgat ctctggcaaa
    10501 gtgatatttt tccgaaacca cgccgtcttt agatgaaata gcgatccata ctgttcctgc
    10561 agattgacct tctaacgtgt ccggtccagc cactccggtg aaagctacac tgtaatctgt
    10621 tcttgctatc tcacgtgctt gaatggccat ctgctccaca cattctttgc tgactgttcc
    10681 atattctgct aatagctccg gatcaatctc cagaaaacca gcttttgttt ggagcgagta
    10741 ggtaacgaat ccgcctggaa atacttcaga tacaccagca atgtcgccta atgcggcttg
    10801 gaaggcgccg gctgtcaaac tttccgctgc tgttacagtc tgcttgtttt ctttcagtag
    10861 ttccactacg acttttgcta gcgaattatc atcgccgtat ccataaaaat attcccctac
    10921 tcgttcttgg attttttctt ctaatgctaa aagagcttga ttccctgcct gaacatcatt
    10981 tgttttcact gtcagtcgta atgtcacttc atttggtttg gcatatggtg cgatcgttgg
    11041 attgatctgt gtctcaatca gatcttttag ctcagtgacc agtcgcgatt caccaatccc
    11101 ataaaagcgc aaaactttag aaattagttt ttcttcagaa ggaaaacgtt cctctagtaa
    11161 aggacgtact tgttccacaa acattggttt caactcatta ggcggaccgg gaagaaggat
    11221 atacgcatgt gtatctgttt gataaaaagt ccctaaagca agccctgtac gatttggtag
    11281 aggaaccccg ccttcgataa tctgggactg ttgcagattg tttttggtca tttttcgatg
    11341 ggttgtttca aaatatgcca ataatttttt gtatccttcc gtattttgta tgagagactt
    11401 accgaggtga gccgcagttg cttcttttgt caggtcatct tctgtcggtc ctaatccgcc
    11461 acataagagt atgagttcac ttcttgtttc agctagagca atcaactctt ctaaacgctg
    11521 ctgattatct cctacaactg tttgataata aacttcgata cctagatcag ctagctgttc
    11581 tgacaagaaa gtggcattcg tattcacgac ttgtcctagt aaaagttctg ttccgacagc
    11641 tattatttct gctttcatta cttcccgctc ccttatatag tatacgctgt atttttatat
    11701 ttttttattt aaaaagaggg caaggagctg tgacaaaaat cttgtcacag ctccttgttc
    11761 caaataaaca gtgttctcct gccaaaacct cggtcataag tcacaatata cataaaacat
    11821 gaaaagctgt tttttgaaat tatcccttgt gactcagagt tagacggcag gctcacaacc
    11881 tctccactaa acgatactta cattgatcct ttgaacacac cgctgttttt gatgaagtaa
    11941 tccacacctg aatagatagt aaagatcaga caagcataaa gcatgatttg atctactgga
    12001 ataccgatca ggctgaatgg gatattattg ataaacagca agataatagc aaccatttgt
    12061 gtagccgtct tgacttttcc cggccaagct gcagccatga cttctccatg ttcgacaagt
    12121 agtaaacgca agcctgtgac ggctaattca cgacagacaa tgatcgctac tacccaacca
    12181 ggggcctttc cttggtcaac caacatgata aaagcagtca taactagcat tttatctgcc
    12241 aacgggtccg caaacttgcc aaaattagtg acaaggcctc gcgcacgggc aatttttcca
    12301 tctaaccagt ctgtgatact agctaaagca aaaataactg cacctactag ctgtgtgaca
    12361 gccagtgtgg tgtctcctac gttaaattgt ccccaatcta aaggtaaacc tacaaccaaa
    12421 atgaaaatcg ggatcataca aattctaagt acagttaatt tatttggtaa attcacacta
    12481 tcgactcctt tcttccctat tctacgtgac tatcagcgaa gtttccaccg atattattta
    12541 cttttccaaa tgaatttatt caaaggagta tttttattga aattgatctt tttgaattaa
    12601 cgaagaagga ccgcgacaca gatttgtcac gatccttctt ttttatacct acaagtaaac
    12661 agatgcgtaa actaatttat acgatcattc tgcgtattga agagtaaggt tcacattttt
    12721 tggactctga ttgttttccc ctggattaac tggtacggat tctccattcg ctttgatcgt
    12781 tgcattgctt gctgcaccaa tcgtgatggt cgcatttgtt gctgtttccg gtaacacggt
    12841 actctgtgtt tcatttgctg ccagtgtccc ttgataaaca taggcattgt ctactagcac
    12901 acctaaccat acacgattga cagcagtaaa ttcaagggtt acaggcttgg tagcgtctgt
    12961 gatatttact gcgatggcac tgccagaatc ttctcctgta gctattgcca ttttcttttc
    13021 ttcacttgat tttgttgttg attctactgt agaagactct ttggtctgcg tgctttgctc
    13081 tgaggaagag gactcctcga ctgatccttc tactttaagc gaagaagctg tgtctccgat
    13141 tattggatca gcttgacgat cttgccaagt catatagccc acgacaacga caatcgccaa
    13201 agcaaccaat cctaataaaa tgacaggaag acttgtccaa aagcgacttg gatgcgattc
    13261 ttcctgatgc attgcttttc tagaagtact tactgtttca ggctgcggac gttcagggac
    13321 cgatcctgtc aatttgcttt tcccatcaaa aacatcgact aaatggtctc catcttctcc
    13381 tacagcttca gcgtattgcc gaataaatgc ccgcacgtaa aatttaccag gcaattggtc
    13441 aaaatcatca ttgtcgattg cttccaaata acgtttttga atttttgtaa tctgctgtaa
    13501 ttcatctaaa gatatttttt tattcaggcg tgcttgccgt aatttttctc cgatggtttc
    13561 aaaagccact cgttcatctt ctccagtctg tttgattctc cgaagcatct gctgttgcaa
    13621 cgaaagacgt tatgtttggg tgctgtgaca aaagtcatgt cacagctcct tttttccgaa
    13681 taaacattgt tctcctgcca actcctcggt cacaagtcac aatatccaat aaatataaga
    13741 agctgttttt tgaacttgtt ccttgtgact cggagttaaa cggcaggctc acgacctctt
    13801 tcttaaacgg tgttcaatca gctgttcctc ggtattagct caaaaaccgg caaaatataa
    13861 ggagatattt ttccgtatgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
    13921 ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agtccaacca agttaaaaac
    13981 attaagaagc tgtttttact tggctgttct tattacttga tgcagggcag ctttttcaca
    14041 acctcttggt acacggtgtt ccagaagtag cttcttcggc aataagccga aatatcacaa
    14101 aaatttg
//
LOCUS       DAFLWZ010000069        13616 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000069 DAFLWZ010000000
VERSION     DAFLWZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.069"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(232..924)
                     /locus_tag="L1V38_002204"
     CDS             complement(232..924)
                     /locus_tag="L1V38_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1316742.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1361..1930)
                     /locus_tag="L1V38_002205"
     CDS             complement(1361..1930)
                     /locus_tag="L1V38_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1316743.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2004..2327)
                     /locus_tag="L1V38_002206"
     CDS             complement(2004..2327)
                     /locus_tag="L1V38_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316744.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2481..3293)
                     /locus_tag="L1V38_002207"
     CDS             complement(2481..3293)
                     /locus_tag="L1V38_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316745.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3647..4495
                     /locus_tag="L1V38_002208"
     CDS             3647..4495
                     /locus_tag="L1V38_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBN1316746.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4640..5581
                     /locus_tag="L1V38_002209"
     CDS             4640..5581
                     /locus_tag="L1V38_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBN1316747.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5571..7742
                     /locus_tag="L1V38_002210"
                     /pseudo
     CDS             5571..7742
                     /locus_tag="L1V38_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7854..10025)
                     /gene="copB"
                     /locus_tag="L1V38_002211"
     CDS             complement(7854..10025)
                     /gene="copB"
                     /locus_tag="L1V38_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBN1316748.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10045..12231)
                     /locus_tag="L1V38_002212"
     CDS             complement(10045..12231)
                     /locus_tag="L1V38_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBN1316749.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12231..12440)
                     /gene="copZ"
                     /locus_tag="L1V38_002213"
     CDS             complement(12231..12440)
                     /gene="copZ"
                     /locus_tag="L1V38_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBN1316750.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12453..12893)
                     /locus_tag="L1V38_002214"
     CDS             complement(12453..12893)
                     /locus_tag="L1V38_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBN1316751.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12967..13506)
                     /locus_tag="L1V38_002215"
     CDS             complement(12967..13506)
                     /locus_tag="L1V38_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1316752.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3834 a         2843 c         2416 g         4523 t
ORIGIN      
        1 gtacatccta aaatataagc tatttgttta cttctgtaga atatatactt tgttgttaga
       61 taagttgcac atgtttatag aatctaaata ataaattttt atgtaccgcc cctcaaagtg
      121 aactgaaccc caaaagttga actatttaat ggactgtttc cgatattcta ctggagatag
      181 tccattaaat agttcaactt ttggggttca gttcaaagag ggggggattt tttatcgttg
      241 tggaatattt aaataccaac gcttgtcatg aaaatcttgt gctccaccct tagtatttcc
      301 ttctggatcg tttgtcgcac gcatcatgac gtatactttc ttattaggga aatcacgcat
      361 attgaaagat acatgatagc caacatttcc taaagtatta taagcttgat ttacgtctgg
      421 tctataaatc ccatcagctc ttactctagc tagttctttt ccagtattgt agtccataat
      481 gaaaatatac tcgtatttat aattagcaat gtgccatcca gctacatgca agtttgcgtt
      541 ttcgatttct ccgaactgat caatgtgggc gtaatttgtt ccatctgtca gcgtagaatt
      601 tgcagcacct gctcgagttg gatcaattac tggtttatcc tccgaagtag ttggattatc
      661 atccgtaaaa ccatgagcca aatcataggc tagtttttct ttacttacac ccatttcaga
      721 aagataaccg taaggatctg tatgatcgcc ccaaatattt tgtgttaccc ataaatgcga
      781 tttgattcct ggttggttat aaggagtgtc taatgttaat ggaataccat atttcattgc
      841 tgaatctctt gccaattcaa cgtatacttt atagttcttt tcaaaagttt ctttatcatg
      901 tgtatgttgt aactcgattt gcacaggact tttggctcac gaggttgtcc tactctacat
      961 cttgctgata gatatgctga aaggaaaaca ccaacattat gttttgcttt ttcagctaga
     1021 acgagacaag caggaatacc tttagaagat atcaaaggtt ttttaggtca taaagatgtt
     1081 tccactacac aagtctatgc ccatatttct cccgaagtga aaaaaagatc aatgaatcaa
     1141 ctagaaaact atatagaaga gcaaataaaa aagcactcaa attgagtgct tttttaagct
     1201 cactatcact aaaactatca ctaattttat ttataagcga acatgtttct atcactgatt
     1261 ttttaaatct agcgaaaaac ccttatctta aaggcgttcg ttcaattctt tggcaaggtc
     1321 ttcaaagcct ggcttgccta gaagtgcgaa catggttttc ttatagctca tgtagaaaaa
     1381 ttttcttgat gatgatttta tccatcaatt gagattgact gttttgctct cctatgattt
     1441 cagctatgat tgtccgattt tgcggttttc ttcttaactg gtagttgatt ttcccagttt
     1501 ccatcaactc gctaagcata tccacgactc cgccaaatcc ggtctttttc gtaataaaac
     1561 ctagtgctac cattcgttca tctagatttt ttgctgtaat cgtcacacca gtaatgagcg
     1621 agtgctgtaa tgtttgggcc agctcttcca tcccttcagc attggatacg acggaagctg
     1681 ttttgttaat aggttcttcg tttatttctt ttggttcttt cctctccact ttcactgttt
     1741 gacgaaggac atctagttct tgcaagagcg tttcgtattg ttcttgggtc agcatcacgc
     1801 cagctacttt ttcacgatta aatatatata cgccagttcc cgcgtctcgc gcttgagcaa
     1861 atacatccat cggcgatcgt ttcacttctg tgatcgaaga tgtgggaact tctaatttct
     1921 ttaattccaa tggatttcct cctttactaa tcgcttttta ttatagcaca gactgacttg
     1981 ttttgatctt ttttccaaag gttttatcgg tttttgccta accagtaatt gatatcggta
     2041 agaagtcttt cgataccaaa tgaaggatgg tacagatacg ttttttgatc ttcgttatgg
     2101 tctagtggaa aaaaatgatc gatgatcact agatctgcat accgaggcgg cttatttcga
     2161 gtacatacat gtatagagat ccgttttcga tgtcttagcg ttttgttcag taccccagca
     2221 agtcttcttg cttcttggtg ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg
     2281 tggacatcta aataccctcg ttcctggagt gttttcagta aaagcatccc ccactctact
     2341 gcggggtgtg caagtgcttg ttggatcgct agccgaaatt gatatagttt atctttggaa
     2401 ttgggaaatt tttctaatgt ttcctgataa taacgaactt cttctatcag ccggtcatgg
     2461 ataccaatta cgtaacgaag tcattcttgg taaagtactt ttgtcagctt tgatttgctt
     2521 tcgctctcaa attcgctatt cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc
     2581 aatttccgat agtcttgtgt ctcttctatc cgtttccacc gcttttcagt aatctggtta
     2641 cagctcaagc gcaaaattgc tagataattt ttttctttta ttggcaaaat ctgctcctct
     2701 ctaaatagca attcaggaaa caattcaaag aatagtgttc gactgtctcc taaaatctcg
     2761 atttctgccg gatcctttct ttgcttcaat aattggatga acatctcaga aaaggactgc
     2821 tctccatcat ctgcaaaaaa atgcggaaaa tctttcaaaa agcaaaacag cagatatctt
     2881 acttttcttt ctgaaccaaa gatctgtgct tttttataag aaaaagaaag gtggtactcg
     2941 ccaaaccact ttctcaatcg ctcttgcgta gaacgatcgt acttctgctc gtaaggttca
     3001 ttcaatagca gatttttcag taaacaaaac gggggtgatt ggatcagaaa aacaaacaag
     3061 agataaggtt cgctatatcc ttgatcataa actaactgaa cggttttctt atgaagaatc
     3121 agctgaatgg gacagtcgct ttccgccaaa cgtttcagat gccgatccac tgttttaaca
     3181 tcgattttca gttcttcagc taaatcagct tttcgccaga tcaaatcttt cattagattg
     3241 attagtgaaa ataaattctg tgcatttttt gataatagtt tttgccatct catcgatcat
     3301 ttctcacctg atttctaaac atattgtttg atcaaaatgg gttcactcct aaaaagataa
     3361 aaaactccct ttctatttat ttaaatacgc aaatcttcct cattattttt tattttactc
     3421 aatttaatcg tattctcatt tcaaaacgaa tgtactttaa aaaaacataa taagatcact
     3481 ttgcttgtag gatgtattcc cttccattac aatgaaataa atagcgattt tatgagaagg
     3541 tgatgtgaaa atggaagaaa aaatagaaga atccaaacaa aaaatcgatc agttgatata
     3601 agaattagaa aaagcggtca tcggcaaacg ttcaactatc caattgatga tcgtggccct
     3661 attagcaggt ggtcatgtct tattcgaaga tattcccggt gtaggtaaaa cgttactggt
     3721 caaagcacta gcaaaagctg tacagggaac cttcagcaga gtccaatgta ctcctgatct
     3781 gctgcctagt gatattcttg gtttttccgt atacaattca caatcaaaag agtttgaatt
     3841 tcgtccggga ccgatcttta ccacgatctt gttagcagat gagatcaatc gtacgactcc
     3901 tcgtactcag tcagcacttt tagaagcaat ggccgagaat catgcaacga tcgacaacaa
     3961 tacataccct ctagacaatc atttttttgt cttagctacg caaaatccaa tcgagtacga
     4021 aggaacatat cctttgccgg aagcacagct cgatcgtttt ttattccgac tacaaatcgg
     4081 ttatccttct tttgatgacg aacttttgct acttttggat aaattcgaaa aagtgttgga
     4141 taacttaaat gaagtattga acagttatga aatagaagaa ataaaaacaa atgtggcgaa
     4201 tgtctttgtc agtcccgaag tggcatctta tgccttgcag ttagtgtcag caacaagaag
     4261 tcatgctgcc atccagcttg gcatcagtcc acgaggaagc ctttccttta ttcaggcagc
     4321 aaaagcttat gctttaatcc atgggagaaa ttacgtcacg cccaaagatt tgcaggattt
     4381 agttccttac gtgttttccc atcgcctgat tttttacgat cgttcattga aggaagacga
     4441 aaagaaacaa atcattcata ctcttgttgc acaaattcct attcctgtga ggtagattga
     4501 ggtagacaat ggaaaaaatc aaagattatt tcattaattt tgtgttattt ctggtatatt
     4561 tcatcattgt gctttttgct cttgtattca acaattcttt aggctggttc ttgttggcct
     4621 tttttactct ttatgtatca tggagcttga tttcattaag cagctttcta aagaaacttt
     4681 cggttacttg tacattgcag ccactcgttt atcgcaaaaa aagtatgcag gttatttttt
     4741 ccatagcaaa aaagagaact ttttctttac ctctccctcg tttacaaatc ggcttcccag
     4801 caatctttgc agaaaaaaac aagagatttt gattcttaca aataaaccgc aagaagtcca
     4861 attgctttgg cagccaaaag aaagaggatg ccatgaaaca ttaactgtca tttttacagc
     4921 ctatgatagt ctaggacttt tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac
     4981 tgttctgcct gctttttgta agattcaagc agaaaaatta cagagagttc tggaaaaaaa
     5041 acagcagctg aacgcgtacc aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc
     5101 aggtgattct ttcaaccgaa tcgattggaa attgtctgct catactcaag agtggttata
     5161 ccgtgaatac gattatcaag aagaagaatg ttctcctctt ttttgctttt ggggttcgcc
     5221 cagtccaaaa tttgaacctc tgctagactt gtatttttct ttatggcatt tgagaaaaga
     5281 aaagcagccg gaacttctga tattaggcaa ccgcgccttt catggcaaag accccggtca
     5341 tacctatttt gcttctttgg aagctggcga tgagaaagct tttttcgcac acttgaaaaa
     5401 atatgcaaaa aaacaaatcg tcctctttgt tcctgagaat tctcctgaag tctcagaagc
     5461 tattgaaaca ttgtcaaaag atcgaacggt ttatcttgtt tatttcgtag aaaaacaact
     5521 catggtccaa gaaaaagaca agatatgttc attgccagga ggtgaatgga ttgacgatta
     5581 aacgggaaaa atggctgcgt ggcgtttact cctttgtgat actaagtgta ggtgctccga
     5641 tatttgtagt agctaatcaa ttgcaaaaca gctaccttct tatcctaact attggtgtcc
     5701 tatgccttat tgtctgctgt attcctaaaa aatgggtacg tttgctgctt tctttgccag
     5761 taatgatagg ttgtttgttt ttatattttc cttcgaagac attttccata ttatggatct
     5821 tacagttttt ttcgtcagtc acagaggaat tcttccatct atcccaaggt aaactttatt
     5881 atttgccaga aaagacagct ttttttctca taatgttgct gatctattta tttattacat
     5941 tgaccgtgga ttacgactat tggtacgcac cctttctttc tttgatggct tacttcatga
     6001 tgcttaccgt ttttcggaaa aaagatttac tgtacgaaat gattgcggta gtaactgttt
     6061 tgttcgtgta tctggcagca aggcaatttt tctccatccg gttgttgtcg ggaaacactc
     6121 gattccagtc attgactaca gttctgctta tttgtttctt aacttttagc gctatcttgc
     6181 ctttatatct tccgaaagta caccaatctc tcgaggaaac gagtgaaccg atccgagaat
     6241 atcttaatga tgaagggctt tatgacacac tccatgagta tcaattaacc ggaagtgcaa
     6301 gaacaggctt cagtgagaat gatgaacagc ttggtggacc tttatatgat aatggcgaag
     6361 ttgtttttac agcgaaccaa aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt
     6421 acaccggttc tggatggata gaagatcagg acgcacccat ccaaccaatc caagaattcc
     6481 ctgttgacat cacgagctac caaaccgtta tagaagacaa agaaaacatt acattgaccc
     6541 taaaaaaaca agttttctta ccttatcctt atggaaatac taccttgact gatttttcat
     6601 tagctagtgg acaaacgctt tactatttgc ctgaaagcca gcgattcatt cctgtcccga
     6661 atgaatcgac acgttctgca actttacaaa cagaaaggtt agtttttacg agagaagaat
     6721 taaaaagcag tcagttaaaa gctgatgatt tagaaaatca gcagacaaat cttcaattgc
     6781 caaaaagttt gcctaaacgt attgaggact tggcggtcga attgaccaaa aatgaagcaa
     6841 ctttaattcg taaagtcgaa gctgtctaac agtatttaaa aacaagcgga aatttccgct
     6901 attccaaaac ggataccggg catactccaa aagaacacga ttatgtggat tatttcctct
     6961 ttgattcaaa agtcggctat tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa
     7021 cacttggtat cccagctcgc tggacaaaag gttttacaaa tgggctcaga acaggcacag
     7081 ataatcaagg gaatgaggaa tacagcattc tcaatagtca tgctcattct tggccagagg
     7141 tatactttcc tggatttggc tggcttccat ttgaaccaac cccttcattt gccaatccaa
     7201 tgggttcaca accagttgct gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa
     7261 atgaaagcga aaatatggca gaaactattt ccagtgagag atctgaggtc attccatcag
     7321 aagaaacaac actcacacca gcttataaaa tcgtcttatt cagccttgga gtgtgtttat
     7381 ccgtcttgtt gttctttcta ttgttattca gaaaatctct gcgctggaca agttatctta
     7441 tctatcttca tttttttgct tctactaata cgattgcata tcaaaaactt cttaaccctt
     7501 tggaaacatt ggtaccgcgc aaacccgcag aatctttgca ggaatatagc ctgcgaatag
     7561 aacaagaatt caagctagat ctgcgtttca ttcgattaac tactcaatat gaagcagaaa
     7621 tatatggacg acaagcagat ccggtaaaat tcgataaaaa aacctattta gaaataacgc
     7681 atataataag aaaaatggta tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat
     7741 aagataaaat ttctggagaa tctacttctg gaatgccgag aaccagctga ttgagtatcg
     7801 attactcgaa aaaaaggttg tgacacgttt tttgtcacaa ccttttttca ttattatctg
     7861 attttcaatg tcaaagcatt tagagctaca actaccgtac ttaacgacat caagacagca
     7921 ccaactgctg gacttaatat gataccaatt ggcgcaagaa ttccggctgc tagcggaatt
     7981 gcaagaatat tgtaacctgc cccccaccag aggttctgga tcattttctt tcgcgtttgc
     8041 ttggctagat caagaaaatg caaaatatct tttggatcgc tgtttgtcaa tacgacatcc
     8101 gcagaatcga ttgcgatatc tgtccctgca ccgattgcca tcccgattga agcacgggct
     8161 aaacttggcg catcattgat cccatcaccc accatgatta cttttttccc ttggtcaagg
     8221 tatttctgga caacagcttc tttatcatct ggtaataaac cgccataata ttcttcgatc
     8281 cctaaataat ctgctactgc ttgggcagcg tttttattgt caccagtaag catgacagga
     8341 gtgatttttc tttctttcaa tgttcggata aattcttttg cttctgtttt tactacgtca
     8401 cctaaagcaa cgattgcagc tagatgattt tctaaaatca ggaagctgat ggtatttcct
     8461 tgttcttggt aaggtttcaa taatgcttgt tctacgttta atccgagacg ctcaacttct
     8521 ttttcattaa ctattttcac ttgttgtttt ttgactgttg cctctagccc gactcctgaa
     8581 agatttttta gattttcagc ttgataaggc ttgatttcat gttctttcaa ataattcata
     8641 atgccaacag ccaatggatg attggcattc gcttccaagg ctcctagata ttgaaggatt
     8701 tcatttttat tgaacgcatc atcaagtact tcgacacccg ttacagtaaa ttttccttct
     8761 gttagtgttc ctgttttgtc cagcatgatc acatctagat cattggcttg ctccagtgca
     8821 ttgcggtttt tcaaaagtaa tccgttttta gctgctattg atgtggaacg agcaacaact
     8881 aatgggatag ctaaacctag agcatgagga caggcgatga taaagactgt taccatacgt
     8941 tctaatgcat taggaagatc tgtcaagaac aaccaggcga tgaatgccag gatacccaca
     9001 attaatgcga cataaaacag ccattttgcc actttgtcag ataatgactc tagcttggat
     9061 ttttctcctt gtgcttttcg caccatttcc ataaccttcg ctagataacc attttcacca
     9121 gttccagtta cttcgatttc gatcgttcca tccccattga tagaaccgcc aatcactttg
     9181 tcattggctt gttttttgat tcctcttgat tcgccagtca cagctgattc gtcaacaatt
     9241 gtttcacctt tcaagattac accatctgtt ggcattttat caccagaccg gacgatcaaa
     9301 cgatcacctt cgtttacttc tttcaatgaa actgtctctt cttttccatc tttcgtcaag
     9361 cgtttcactg attctggcag taattctgct agtttttgta aagcattgct ggcattcgac
     9421 acagcattca tttcaatcca gtgacctagt agcataataa cgatcaaagt agccaattcc
     9481 cagaagaaat ccatgacgtg tgtatgtgga ttgagcagat ttgcgataaa cgaatagaca
     9541 ctataaatat atgcaactgt aatccccatc gcgatcagtg tcatcatagc aggacttttt
     9601 tgtttcaatt ccatcttagc tccacttaaa aatggctgac cgccatagat aaatagtata
     9661 gttgctaaga tcaatacgag ccaatcagaa ccaggaaacg ttacttgaaa tggaaattcc
     9721 attcccatca ttggtgaaaa aagaatgatt gggatagcta ggataagcga tagccaaaat
     9781 ttttgtttga aattccccat gtgcatggaa tgatccatgc cgccgtgttc gtgatccatg
     9841 tgcatcgaat ggtccatttg tttgctgttt gctatatctc catggttatg tcccatgtgc
     9901 atggaatgat ccatctgact atggtcatgt ttcatctcca tctgtttttc atgagattct
     9961 gtactttctt tgtttactac ttctttttta tgctcatgtt ttttctccat atcgttccca
    10021 ttcattttta ctccatccct tctcttactt tttcatgtgt cgatttaagc acagggagtt
    10081 caacaataca ctgacggaac taaacgccat cgctcctcct gcaatgattg gattcaaaaa
    10141 gcctagtgcg gcaaaaggaa taccaatcgt attatagaca aaagcccaga aaagattttg
    10201 tttgattttt ctcaatgtca acctagacaa ctcgattgtt tgtgcaatgg atgccaaact
    10261 gctattcatc agcgtcacat cggctgtttc catcgcaatg tccgttccac ttcccattgc
    10321 cataccgaca tcagctaatg ctaaggccgg tgcatcattg attccatcgc ctgccatacc
    10381 gacttttttg ccatctttct gaagtttttc tacgtaggct gctttatcct ctggaagtac
    10441 ttcagcaaag atatgctttg gatcaatacc aacttgttta ccaatcgttt cggctgccag
    10501 tttgttgtct cctgtcagca taaaaacatc taatccttta ttctggagct gcttgattgc
    10561 ttgtttgact tctagtttga tttgatcagc cacggcaatc aacccgatca cttgcttttc
    10621 atcagctaaa aacatgactg tttttccctg ctgttctaat tctaacgcgt gttcttggta
    10681 ttcatcaaat gataggttca attcaattaa tcgtttacgt gtacccgcaa aatagcgtac
    10741 tccgttaatc gtaccgctga ttccagcacc tgggtgggct gtaaaatcaa tcatatcgta
    10801 tgttgctgct tcttgcagtt ttccgtattc cacgattgct ttacctagtg gatgttcaga
    10861 agcttgttct aaagtataaa aaatagatag gacttcttta gaaccgacta gatctgtaac
    10921 tttgggcttt ccttctgtaa tcgttccagt tttatccaaa acaatgctgt ctaagtgagc
    10981 agctgcttct aatgcttctc cgcctttaat taaaattcca tttcgtgcac caacacccgt
    11041 tcctaccata atagctgttg gagtcgctaa acctaatgca catggacacg caatgactaa
    11101 tacagagaca ctatggatca atgcgagttg ccaatcacca gtgatcaaac ctgtagctat
    11161 gagcgtgata aacgcgatga ctaatacgat cggaacaaaa atccctgaga tccgatctgc
    11221 gattttttgg attggggctt tgctcccttg agcatcttcc accatttgaa tgatttgcgc
    11281 taatactgtc tgcttgccga cttgtgtaac ttccatgtga agtagaccat tcgtattgat
    11341 tgtcccgcca aagagcgtgt catccggatt cttttctaca ggaagatttt caccagtaag
    11401 catactttca tctatcgcac tgcttcctga aataattcga ccatctgctg gaatctgctc
    11461 accaggacgg atgactagtt gatcaccaac gactacttct tcaatcgcta acgtttcttc
    11521 tttcccgttt cttatcactt gggcggtttt tgtttgaaga gacatcaatt gtttgattgc
    11581 attacctgtt ttcgtttttg ctgtatgttc caaatatttg ccgagcaaaa tcagcgtgat
    11641 gatcatactg ctgctttcaa aataaagatc ttgggggtgt ccacggaaaa atccgttgta
    11701 aatgctcaat gcaaaggcag ccgatgttcc aattgctacc aatacatcca tatttggtgc
    11761 tttcgtcttg attgcatggt acgcaccttt ataaaaacga gcaccgacat aaaattggac
    11821 aggagcagac agcactaact ggacgattgg aaaatgaaaa aagtgaacaa tcgccgcatg
    11881 gcttcctaac atcatagcaa tcattgacaa catcaacggc aaagtcaaaa ccgtactcaa
    11941 tataagatcg aatagcattt ttttcaaata cgcttgcttt tcttctgcaa ttttttgttt
    12001 gtgggcttca tcgtacaaaa ttgcaccata gccgatgttt tctacgcttt ggattaattt
    12061 ttcagtggtc gtcccttcat atttgacact tgctttttca gtggccaagt tgactgtggc
    12121 attgaccaca ccaggttgtc cgttcagctc tttttcgatc ctagcagaac aatttgcaca
    12181 agtcatacct gtaatgacga acgtatccat tttggtttct gctgttgcca tcaaatcacc
    12241 tctgctttat aacccaatcc attgattgct tgacaaatct tttcggattg aacttttgtt
    12301 tcatcaaact tgaccgtacc gtttgctttt ttcaaattta ctttcacttt ttgcacgccg
    12361 tcaagtgcgc ttactgtttc ttctactctt gctgcacaat gattgcagct cataccttcg
    12421 attgaaaatt gttgtttcat tttttcttcc tcctattgat gttgtttaca ttcacattga
    12481 cctgggatac agttacattc gatcgtatct actggttgct tttgttccag ttgtttcaaa
    12541 atctcattga tatcttcttg agtcaaagtg gcttcttcta ctagatccgc aatcgtctct
    12601 ccaatccttt ttgcacagat atgggaaaaa agattttccg tcgcactgcg aactgtttcc
    12661 atctccgaga cagctggata ataaatgaat ttttttcctt cttgttctgt ccagatcact
    12721 tcttttttta ccaaacgacc cagcaaagtt ttgatcgttg ctggtttcca atccatcgaa
    12781 tcagctaaga tctgcgtgat ttcttgggct gtcgtctgtc caagtgtcca aataacacgc
    12841 atgatctccc actctgaatc actgatcttt actggcgttt tgactttttc catttatttc
    12901 acacctttcg tttacaaatg taatcattat cttatgaata cagattacac ttgtaaacaa
    12961 aaactgtcaa ttatttttgc tctctatttt caatttagtt aaaaattctt gtttctctcg
    13021 tcttgtttta aggatgatca gtttatttct tgcattagct acttggatca gctgctgtat
    13081 tttcggttca ttgttttctt caaaatgcca gataaaagat aaaaattcta agtattccct
    13141 gtttagtttc tccgaaaatg attcaggcat atctggccga gattttttgt ttatctttct
    13201 ttttagagaa cgccaaacta ctcggtagat ggcgagataa cgcggcactt taagccaaat
    13261 gatcttatct gcttctttaa tcctttcctc taatgtagaa gtataatttc cttcaacgat
    13321 ccatgacgga ttagatacca taaacaattg ctgttcttgc aaaaaccact tttttgcctg
    13381 aatactgtag tctgttgtat gccataaaag gtctagcggc agtagcggaa agtcggtgat
    13441 ttctttgatc ttccttgcga gggtcgattt tcccgaccca ctttgtccaa tcacgatgat
    13501 cttcattctt ctccctcact tctctttgga atttggttcg atcataccac ttataacgcc
    13561 gcaaaaaaac aagggactgt gacaaaagtc gtgtcaaagt cccttgtttc gaataa
//
LOCUS       DAFLWZ010000070        12898 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000070 DAFLWZ010000000
VERSION     DAFLWZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.071"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(2..1150)
                     /locus_tag="L1V38_002216"
     CDS             complement(2..1150)
                     /locus_tag="L1V38_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1316753.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(1272..1868)
                     /locus_tag="L1V38_002217"
     CDS             complement(1272..1868)
                     /locus_tag="L1V38_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1316754.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(2068..4710)
                     /gene="alaS"
                     /locus_tag="L1V38_002218"
     CDS             complement(2068..4710)
                     /gene="alaS"
                     /locus_tag="L1V38_002218"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBN1316755.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            5098..5529
                     /locus_tag="L1V38_002219"
     CDS             5098..5529
                     /locus_tag="L1V38_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1316756.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(5574..6923)
                     /locus_tag="L1V38_002220"
     CDS             complement(5574..6923)
                     /locus_tag="L1V38_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1316757.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(6993..8156)
                     /locus_tag="L1V38_002221"
     CDS             complement(6993..8156)
                     /locus_tag="L1V38_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1316758.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            8285..8608
                     /locus_tag="L1V38_002222"
     CDS             8285..8608
                     /locus_tag="L1V38_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316759.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(8791..10140)
                     /locus_tag="L1V38_002223"
     CDS             complement(8791..10140)
                     /locus_tag="L1V38_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1316760.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(10209..11162)
                     /locus_tag="L1V38_002224"
     CDS             complement(10209..11162)
                     /locus_tag="L1V38_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBN1316761.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(11264..12454)
                     /locus_tag="L1V38_002225"
     CDS             complement(11264..12454)
                     /locus_tag="L1V38_002225"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBN1316762.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         3709 a         2713 c         2227 g         4249 t
ORIGIN      
        1 tttaatataa aagataattg tgatcaaacg taatttccaa ttggtaatct ccgatttttt
       61 cttctatttg actacgtaag attctttcta gttctgtatc aacaaactgg aatttctcag
      121 ggaccactac atcaaattgc agcgtttttc cttgatgaat tactctaaaa tcatgaatat
      181 taagccctgt acctgtttca agaagaattt gctttaactg ccgcaagata ttatagtatt
      241 tttcgttatc aacaggcatt ggatccaagt gacagacaag ttccacatcc aaagactttt
      301 taaagtcttt ttctatcaga tcaataatct tatgagccac attcaaattc attgattcat
      361 ctacttcgat gtggactgat gcaaagcgtt tattgggtcc atagttatgc accaataaat
      421 catgatagcc aagtatatca tcgcaagcat ttaaatgctc ttccatttct tcaatctctg
      481 ctggcgttgg gcgacttcct aatagttcgt atacaaaatt tcgaagcatc gtcaatccac
      541 tataaaggat atataatgct aaagcaaaac ctatatatcc atcaatacgc catccagtta
      601 cccattcgat tgctgctgaa agcaatacag ccagtgtagt aaagacatca ttataactat
      661 ctgttgctgt agctctcaat gtttcagaat caatggattg cgcaataacc tgatacattt
      721 tgccttgtgc aaatttcaaa aagatggaaa tgattaggac aaaaaagacg atgggtgtta
      781 aagagacatt ttctggatgg atgatttttt cagcagaaga ctctaaaaat tgaaatccta
      841 cataagtaat gatgatcgaa acaaataacc cactgatata ttcgaagcgt tcgtgtccat
      901 aaggatgttc ctgatctgct ggctttgcag caattttaaa tccgatcaaa gtcaatatgg
      961 atgaagcagt atctgataga ctgttcactg catcagccat aatggagaca cttcctgaaa
     1021 aaagcccgat cattagctta gagacaaaca agatcagatt cgtaaccaat cctaagatac
     1081 ccgctagtac tccttttttt gtccgctgtt gcggtatttg tttctttttt tcttcttgtt
     1141 tcttagccaa gttttttacc ccttctagtt tgcttgttgc tcaggtaaaa agatggagag
     1201 gacgattgtt ttcctctcct ctcttccttt ttctatctat cgtgcgtcct attactatta
     1261 aaagatggtc attattctgg tttcaacggt gttgctgcaa ataacgcttt tgctagtaat
     1321 ggtgttatga ttcccgcacc tattgcttct ggtatcccat tgattgctgc aacccctgct
     1381 aaggttttaa ataaaagagc agagtctaca ccataggcat ctgccgttgc acctgtataa
     1441 aataatccca tgaatcctaa cactaagact gtattgacca atgaacccag tacccctgca
     1501 aaggctgagc tgatcgttat tgatttattt ttttgataaa tccagtggaa aaccaagcct
     1561 gctactaagc caacaagtac tctgggaact accgagataa tcggattcgt gaacactaat
     1621 gtatcaaatg gcgttgttgg catggcatag gcacgaacaa ttgtagcgat tccccaaaac
     1681 aagccaatca ccatgccatc ttttgggcct aatactactg cagcaataat tactgtgata
     1741 tggataattg ttaaactaat gaatcctaat ggaataaacc ccagccaagg aaccatcgct
     1801 tgtacgatga tgattgctaa caagatcgca cgtaagacta gtcgaaaggt cttatttcta
     1861 ctattcattt tttcacccct ttttatttat actaatcgta aaaatttctg tcactttcgt
     1921 caactaaaga ccatccgaat ccgaccattt gattagatgc gccatccaat tgaaaaaagt
     1981 atgagggcaa gacttgtttg tcttcgcccc cataatcatg tttcgttcaa tgtttgaact
     2041 tttgtttttc tgtcaaacgt aaacgcccta ttgttgcgca acccattctt tcgcagcttt
     2101 aagtgcatct ggaataccag caggattttt cccgccagct tgtgccatgt ctggacgtcc
     2161 accaccgcca ccgcctactt tcggtgcgat tgctttaatc aagtcgccag cttttagtcc
     2221 agcttcattt gattctttcg tcattgccgc tagcagactg acttttcctt cttgttcgtt
     2281 tgctaaaaca agaatatctg aaatattttt ttgtttccat tggtcagcta attgacgcag
     2341 ctgattcata tctttcactt ttacttgtgc tgcaatgatt gtttttccat tgatcgtttc
     2401 tggatctttg aatacatcac cagcttgttg attcgctaac ttgctagcta attgttcatt
     2461 ttccttttgt agctctctta cttgctgttg caattgttcc gcttttgaaa caacttcttt
     2521 caattgaggt gatttaacaa ttgttgctac ttgttttagt tgtttttctt cttcttcaag
     2581 tagttcgtac gcttctttac ttgttacagc ctcgattcgt cgcacgcctg caccaattcc
     2641 tgattcagaa acgattttga agattccgat gttttctgta tttgctacat gtgtgcctcc
     2701 gcacagttcg attgaccagc cgccaatatt tactactcga acgtcatgtc cgtatttttc
     2761 accaaacaaa gccattgcac ccatgttttt ggctgtatcg atatctgttt caattgtttc
     2821 aactgggata gcttcccaga ttttttcgtt gacgattctt tccatttcag ctaattcatc
     2881 tgaagtgatt tgaccaaagt gggtaaagtc gaatcgtaaa tgtccaggag cgactaaaga
     2941 accagcttga tttgcatgct cgccaagtac ttctttcaat gccttgtgca gtagatgggt
     3001 tgctgtatgg tttttgatga tccgattgcg catcgattga tcgatcaata gatgataggt
     3061 ttgtccttca ctcattggtg cttttacttc tacggtgtgc ataaattgac cattaggcgc
     3121 tttttgaaca tctgtaacaa ctgctacgat ttcgcctact tcattcatga tccatccttg
     3181 atccgctact tgcccaccca tttctgcata gaaaggtgtt tgatcaaaga tcatttgagc
     3241 ttcaccttct gcgacttcat tcaaaagaga ctcaccttta acgatgacca ataattgact
     3301 atctgattct tgttctgtgt atccaatgaa tttactttct actttgatat ctgtcaataa
     3361 agcagattgt acccccattg atttttcagt actgcgggca gagcgagcac gttcgcgttg
     3421 tgcatccatt tctttttcaa aaccagcatg atcaactttc agtccttcat cttctgccac
     3481 ctcttccgtt aattctaccg ggaagccata tgtgtcgtat agtttgaaga tgtcttttcc
     3541 tgctagagtc gtcccgtttt cgttttttac ttcttggatc acttgattta agatttccaa
     3601 accttcattg attgtttcat tgaaacgttc ttcttctgta cggataactt tttcaataaa
     3661 ttctttttgt tgaagtactt caggataata acttaccatg atttccccaa caacagggac
     3721 taaacgatat aagaatgctt gttcaatacc taattttttc ccatgcatga cagcacgacg
     3781 aagcaaacgg cgtaagacat accctctccc ttcattcgat ggcaatgcac cgtcgccaat
     3841 agcaaatgaa agggcgcgaa tatgatctgc gattactttg taagaaatat ctgttactgg
     3901 gttttcacca tattttactt gtttgcttag cttttctacg gcgtggataa taggcataaa
     3961 caagtctgtc tcaaagttcg ttgacgcatc ttgaacgatt gagaccatgc gttccaatcc
     4021 catccccgta tcaatgtttt tatgaggaag tggttcaaat gtgttatcag gcttatggtt
     4081 gaattctgaa aatactaagt tccagatttc taaataacgt tcattttctc ctcctggata
     4141 gttttcagga tcgtcttctg ctaaatcgtt ataagcttct ccacggtcat agaaaatttc
     4201 cgtatccgga ccacatgggc ctgcaccgat atcccagaag ttgtcttcta catcaataat
     4261 gtgatctagt ggcaggccaa cttcttcatg ccagatgcgt tttgcttctg tatcttttgg
     4321 ataaactgtt acataaagtt tttctggatc gaatgccatc cattttggat cagtcaaaaa
     4381 ttcccatgcc cagtggatgg cttcattttt gaaatagtca ccaatcgaaa aattacccag
     4441 catctcaaac atcgtatggt gccgtgctgt tttaccgaca ttttcgatat catttgttcg
     4501 aatagatttt tgggcatttg tgattcttgg attttctggc acaactgaac catcaaaata
     4561 ttttttcaat gttgcaacac cagagttgat ccacaataag gttggatcgt tcacggggat
     4621 caaagacgca ctaggttcaa tcgtatgtcc tttagattgg aagaaatcaa gaaacatttg
     4681 tcgaacttgt gcactactta attgtttcat gtcattacct gctttctata aattaaatac
     4741 aaaaaaacac catcacagcc aaggacgaaa actcgcggta ccaccttgat tgcaatgatg
     4801 tgtaatcatt acctcttaaa ctcgataacg ctgagctgcg tcggtatttc taccaaaata
     4861 gaaaaaggga gcaatttgat tagtgactat tcttttttca gccaagaaag aattttctgt
     4921 gagtcttaaa aaacaaatca tatccttttc gtacttaatt agtatacgca ttctattgat
     4981 cactgtcaat atctcaattt ttattttcat ttccttttgg tcatactcca cgatttttgg
     5041 tacgataaga ataaaggaat caatacatct ctgctattca tgacaaggag gaatatgatg
     5101 aaaaaaatag ttggagcgga tgaatggata cgcgcagcta gctgcttttt gagatatcaa
     5161 gtttttgtat tagaacaagg gattcctgca gaactagaat tcgacggaaa agatatcccg
     5221 caacaaacct attatctatt tcttgatcaa aaaagaccag tagctacttt gcgttatgaa
     5281 aagaaaacac ctacttgctt caagccggaa cgattttgcg tagcaaaaga ataccgagga
     5341 aaagggttag gcggtcagtt gcttgaagct gctgaaaaac gggcggtttc agaaggttgt
     5401 cagactagtt atgtagtagc tgaaatgacg gctgtagatt tttatgaaaa acaagggtat
     5461 catacttgca cagaaccttt tattgaagat gaagtacttt gtatcggaat gaaaaaaagt
     5521 ctagcttaaa aacaagagat tgtgacacgc cttttgtcac aacctcttgt tttttattta
     5581 tgtgaatttt tcttattttt acgagcagta cggctttgct gtctgcgttc gattttgcgt
     5641 tcttttttat ttttttctgc aattgcccaa tcgatttttt tcttataacc aggcttgatc
     5701 tttttctttt tcttcttcac aagaccaatc agcgtgggat ctaatacatc ttttgatttt
     5761 tctcgtttgg cacgtctatt acgatcgtat gttttgacga tttccccgtt tttgatttct
     5821 tttggttcaa atgagacgcc caatttttct atcgcatcaa tggcttgctc atcatttggc
     5881 gaatataacg taatggccgt tccttttaag ccattacgtc cagtacgtcc gacacgatgg
     5941 ataaagaagt ctagatcttc tggaatttct gcattaataa catgagagac accttcgata
     6001 tcgatccctc tagcagctaa atcagtcgct acaacatatt gatactccag attctgtact
     6061 tgtcgcatca ctcgttttct ctctcttggg gtgatgtctc catgaatctt tgctactttc
     6121 aagccttggt ttttcaagta atcggcaatt tcatccacat gctgttttgt attggcaaat
     6181 acgattgcta aataaggatg accaattgtc agcagttgat aaatcatttg attctcatct
     6241 ttaccttttg ttgaaatcag ccaattttca atgtcttcag aaataactgc ttttggtttg
     6301 atttcttcaa tgattggatt ttccatgtat tttcgtaaga atggacgaag tttttctgga
     6361 atagtggcag aaaaaactaa aaactgcagc ttttctggta atcgacttgc aatttggtct
     6421 acttcattta aaaaacccat atccaatgtc atatccgctt catcgacaac aaatgcaaat
     6481 gcggtgtgaa tcttcagcgc ttgttcattc atcatgtcta atattctacc aggcgtgcct
     6541 actacaacct gtggctgttg gtgatgcaga cgatttaatt gacgctgttt gtctgtaccg
     6601 ccgacaaaat tcgagacacg gatctccggt gtagaaaatt tagcgatttg tgtagctgct
     6661 tcatagatct gtgcagctag ttccctactt ggagctgtaa taacaacttg tacttcctct
     6721 ttttctgcat tgattttttc aaacaaaggc aacaaaaacg tatgtgtttt tcctgtacca
     6781 gtttgagatt gcccaatgat attttttcct tttgcaatta aaggaatcaa acgttcctgg
     6841 acctctgtgg gctgtttgaa gccctttgcg gttaacgctt cattgataaa cggtttgaag
     6901 cggaatatat caaaattatt cattcgtgca cctcttctct ttaaattatc acgactttgg
     6961 cattataaca cagacaaagc gtttttgctc agctaatttc gagaatcatc atcctttgtt
     7021 tggccaatcg tgctaacagt atatgtgtga ctagcttttt cataaaacag aatccgtttt
     7081 tttctcaaaa atgatagcaa gatatttaaa ataaaaatac cttgtagtaa caagacaccg
     7141 agagaaatga atactgcact catctgcaac accgtattcg ttgtcgaatt catgatttgc
     7201 tgaagcaact gccccaacca gcttaaacca taaaaaagaa agtacagata cccgtagcgg
     7261 atcatcaatg cttttaaaga aattcgttcg cggtcttctt ccaccaaacg gatacgcaca
     7321 atttttttgc caagtgtcca tccattggtt ataaacggta caatcataaa gtatacccct
     7381 acttctaata aaagccacca gatatgagaa gtaactgccc ctgaatcgaa cgcaatttta
     7441 aagaaaatcg ccgctaccaa attaataaga gataaaaatg tccagtcgat caaataagcg
     7501 accaagcgtc gagtcaatga gacagtcttt cctttttcat aagaaagttc atccattcgt
     7561 cttcttgtag gaagcataaa tgtaaataac ggcgtaacga caaaaccaat gattccaccc
     7621 aatgtatttg tcactaaatc attcacatca aataagcggt atggtcttgg gtagataaaa
     7681 taaagtccac ttagctgcgt caattcaaaa aatagagaaa ggcagaaact agcaatcatc
     7741 gttttcataa aagaaagccg gaaataatat cttaaataaa tgccaaacgg tatgagtaat
     7801 aaaacattaa aagctggttc caaaaataca ctctgcttca ttgccggcag gtaggtacta
     7861 ggttcagaca agaccaatac cgtgttgtct ctgaaatgtt gccatgaagc aaataaatgc
     7921 agctccatct ttggccctgt catttgggca accgtctcct ttgccggaag tggtaagatc
     7981 accaaaaaat acgcacacaa taaataaaaa acgaaagaat acaaaataac tgcccttgtt
     8041 actagaaatg ttccatactt tcgatattca taaataaaaa aaacagatga gatcgctaag
     8101 gctaaaaatg gaaaaacaat cagcgcaaaa cgaatcggtt cgatataact tgccatatga
     8161 ctcctccttg attctttgta tctctcttat cttagcagtc ctttgctgtt tcaagcaagt
     8221 aacgaggcta ttatttctca tttctttcaa agtaaagtaa gataaacaca aagggggtgt
     8281 cgagatgctg aatatgtact ttgtttttgg cgtacctatt tttttactgt tcctttatgc
     8341 tacgatcgct tatgtaagaa aaagaactac aattcattat ttaggattta ttctcctgat
     8401 tatttcgggt ttcatgctag tcttcaatct tcagacttgg cagcaagcac ttcttgaaat
     8461 ggataaaatg actccacatg ctttgtctaa agtgcttggc taccctgtct atctgatttg
     8521 gcttcccatt ttcatttctg gttgcttggt tttattaaat atttatcgcg gcgtacgccg
     8581 aatagttcag ttacgcaaat caaagtaaaa gacagaaatc ggttgagccc gatttctgtc
     8641 ttttactttg ctatttcatc gtagacaaaa cgacatttac gtgatcaaaa ttaacgagta
     8701 cttttgacat ttcttccacg tactcctcat ttaaataaaa tattttgttt ggcagagaag
     8761 tgcagttcta ataaaattcg aatgttttag ctatctacgt tttaaataga gataaatcgg
     8821 gataccagca agtgtcaata ctatccccat cgaagctaaa aaggtctgag tgataagcgt
     8881 gcttgatacg ataaaagtcc ctccaatgat tgctactagt ggaataaacg gatacattgg
     8941 aactttgtat ggtcgaaaca aatcaggttc ttttttacga agaagaatga caccaacaaa
     9001 gaccatcgta taaaaaatcc aaatgacaaa gatcagcata tccgttagtg tatcaaaacc
     9061 accgatcatc atcatgccaa tagcgatgac tagctctaag atacctgcgg ctacaggaac
     9121 tttagtttta tcatgaagtt tagcaaagag cttgctaaaa ggcaggttgt tttcttttgc
     9181 cataacataa gggagacgca ttccagtaag ggtatagcca ttgatggttc cataaacaga
     9241 aatcaagata ccaactgtga ccagtcttcc accgaagccg ccaaaaatca tttttgcaac
     9301 gtcacttgcc gcattgctgt ttcctgcgac tccgtcgata gatgcggttc ttaagaacac
     9361 cgcatttact aataaataaa cgatcatgat tccgatgatt cctaaagaaa ttgcttttgg
     9421 caaatctttc gccggctttt tcaattctcc cgaaatattt cctacgtgta tccaaccgtc
     9481 gtatgcgaac atcgttgcta gcaagcccgc tcccaaggct gagaaaaatg aaagattttc
     9541 tcctgcttgg atcggaaaca gttggaagtc tactccttct tgtcggaaca aaccgaaaat
     9601 gacgatcaca aacaaaggaa taagcttgca gacaagcgta atcgactgaa aagcccctcc
     9661 agctttagaa cctaaaaaat tgatcaacag gatcgataca gcagctgtaa cagctacggg
     9721 aacaatcatt gactgggaaa gaccaaatag attgacgaac tgtgtaccga aaatgatcga
     9781 caaggctgct acatttgctg gaaaataaat cacgacttgc gcccagccca ataaaaaagc
     9841 tgctgtattt ccgtaaatcc gttcgatata tttaatcatc cctcctgttt ctggaatagc
     9901 agctgccagt tcagctcctg ttagtcctgc acagacagaa atcataccac cgagaaacca
     9961 agaaaacata tgcaaactgg cggatcctgt aacttctgct acgcttgcgg ctttaaaaaa
    10021 tacccctgca ccgatcactg tgcccataac agtcgataaa gcagtaaaaa atcccatcgt
    10081 acgttttaat tcattttcta tttttacttc ttttactggc gtggcttgat attcttccat
    10141 cccttgtccc ctttcatacc atagccaatc ccaaaagtat aaaaaacttt ttggatgtgg
    10201 ttcttgtttt ataccgtctc taccaatttt tctttcagtt tttccaacat atcctttgtc
    10261 atcacatcta agtcgtattt cggcgaaaag ccccattcct cttgcgcaca agaaacatct
    10321 agtgaatttg gccaagattc tgctattgac tgacgtacag gatccacatc ataatccatt
    10381 tcaaaatctg gtatgatttt ttgaatagat gctttgatct cttccgggtc aaaagacatc
    10441 gccgatatat tgaaggcatt tcgatgaacc aatcgatcag gatctgcatt catgagtttt
    10501 ataatggcat cgatcgcatc tggcatatac atcatatcca ttgatgtacc ttgatcaatg
    10561 aaactagtgt actttccttc tttgattgct gaataataaa tatcgactgc gtagtctgtc
    10621 gtaccgcctc ctggcaaggt tgcataagaa atcaatccag ggaaacggac accacgagta
    10681 tctacgccat atttcacata ataataatca catagtagtt ctccagctac cttcgttacc
    10741 ccatacatgg ttgtaggacg ctgaagagta tcttgtgggg tatgatcttt tggagtattt
    10801 ggaccaaacg cgccgattga acttggcgta aaaaatttca gctggaattc tctagcgact
    10861 tccaatgcat tgaccagccc agtcacgttc aaattccagg ctaattgtgg ttttgcttct
    10921 gcaacagctg acaaaagagc agccaaatga atcaatgtgt ccacttgata ttgttctgct
    10981 atgctgcgca ttttttcgta atccattaca tctaggatct caaagatatc gtttttctca
    11041 atgacttcag gcatgcgtat atctgtcgca atgacatttt cactgcctag ttcttgacgt
    11101 agccgtgtga tcaactctga accaatttgt cctaaacatc ctgtcaccaa tacttttttc
    11161 atgatgatcc tccctgatct tttttactac tatcttcaga tgattaacaa tatatgcgtg
    11221 aacatgttct ctaattttaa atagacgaaa aaactaaatt tagttaaata atttccattt
    11281 cttttcctat tttttgataa actgctactg cttcatcaag catttccctc gtatgttccg
    11341 cagtcggcat atttctgatc ctgcctgtcc caagaggcac agttggataa acgattggtt
    11401 tagcataaat cccatgttcg atcagcttct tagagaaagt ctgagtcact ttttcgtctc
    11461 ccaaaatgac tggagtaata ggtgtttcag acataccgat gttatagcct acttttttca
    11521 attcttcttt aaaataatta gcattttccc aaactttttc gacaagttcc ggatgttctt
    11581 gcatcaaagt aatcgaagcc aatgcagctg cagctgcacc tggagttagc gaagtagaaa
    11641 ataggaatgg ccgacttcta gctttcaacc agtcgattag tgttttcgat ccagctacat
    11701 aacccccaac aacacctata gctttcgata acgtgcccat ttgcatatcg attttgtcgc
    11761 ttaatccaaa atgcttgacg gttcctgcac cttttccagt tacgcctgag ccgtgcgcat
    11821 catcgacgta ggtgatcagt ccatattttt caacaatcgg aataatttcc ggcaatcgtg
    11881 caatgtctcc atccatggag aaaacaccat ctgtgatata catgattttt ttatatttct
    11941 tactttctat cgcttccttt gcttttttct caaggtcttt catatcttga tgtttaattc
    12001 ggatgatttt tgctccggat aagcggcaac cgtcaataat agatgcatgg tttaattcat
    12061 ccgataagat agcatcttct tttgtcatta ctgcagagat agcgcccata ttgcagttga
    12121 atccagattg aaaggcgatt gctgcttctg tccctttgaa ttctgcgatt ttttcttcta
    12181 attgctgatg gattttcagc gaaccattga tcgttcggac tgctcctgct cctacaccat
    12241 aagtttcggt tgcttcaata catgcttttt tcaattcttc gcgattggca aatccaagat
    12301 aattgttgga tgctagattg atcatctttt ttccgtctac gatgatacaa gcaccatttt
    12361 cactttctag tatgtcgatc gtattgtata accccttttc tttcagttga tccaattctt
    12421 tctctaaata cattgttagt tctttggaag acattgtctc cacctccata ttcatctgtc
    12481 ttgcagaaca taccaaacat atatcgtgtc attcatctac aaagcaagta tgctatattt
    12541 ttgataacgc ttacactgat tatgagaatt atttaaccac attttttatt tacagtatct
    12601 ttttactttc aaatgactta tatagtatga acaattacct tttagataat gatctatttt
    12661 actctacctg ggcagataaa tataacacaa ccattgatag aagccctttc gttaaaatca
    12721 attgtattct gaatatttaa tttatttatt gcatagacca ataaaaatac ataaaatttc
    12781 catcttcgtt tatcagcaat ttttaatttt actctctgaa tatttcttaa aagttttact
    12841 tgttgaattc gaaaaaagga ctgtgacaaa agtcttgtca cagtcctatt cttccgaa
//
LOCUS       DAFLWZ010000071        12742 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000071 DAFLWZ010000000
VERSION     DAFLWZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.073"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            101..544
                     /locus_tag="L1V38_002226"
     CDS             101..544
                     /locus_tag="L1V38_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1316763.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(550..1734)
                     /locus_tag="L1V38_002227"
     CDS             complement(550..1734)
                     /locus_tag="L1V38_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBN1316764.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2002..2700
                     /locus_tag="L1V38_002228"
     CDS             2002..2700
                     /locus_tag="L1V38_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1316765.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2707..3384
                     /gene="nth"
                     /locus_tag="L1V38_002229"
     CDS             2707..3384
                     /gene="nth"
                     /locus_tag="L1V38_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBN1316766.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3510..4043)
                     /locus_tag="L1V38_002230"
     CDS             complement(3510..4043)
                     /locus_tag="L1V38_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316767.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4340..6721)
                     /locus_tag="L1V38_002231"
     CDS             complement(4340..6721)
                     /locus_tag="L1V38_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1316768.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6711..7358)
                     /gene="recU"
                     /locus_tag="L1V38_002232"
     CDS             complement(6711..7358)
                     /gene="recU"
                     /locus_tag="L1V38_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBN1316769.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7422..7961
                     /locus_tag="L1V38_002233"
     CDS             7422..7961
                     /locus_tag="L1V38_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBN1316770.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8051..8470
                     /gene="gpsB"
                     /locus_tag="L1V38_002234"
     CDS             8051..8470
                     /gene="gpsB"
                     /locus_tag="L1V38_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBN1316771.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8492..8859
                     /gene="rnpB"
                     /locus_tag="L1V38_002235"
     ncRNA           8492..8859
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="L1V38_002235"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9068..10234
                     /locus_tag="L1V38_002236"
     CDS             9068..10234
                     /locus_tag="L1V38_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBN1316772.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10280..11776
                     /locus_tag="L1V38_002237"
     CDS             10280..11776
                     /locus_tag="L1V38_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBN1316773.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11857..12540
                     /locus_tag="L1V38_002238"
     CDS             11857..12540
                     /locus_tag="L1V38_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1316774.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3609 t
ORIGIN      
        1 tttttcttgg tttcagattg ggttttccta caaaatattt ttatctttgt tgaataggaa
       61 acaaaaaaac aatataatga aagaaaaaga aggtgtagaa atggataaaa gacaactgct
      121 aatagaagaa tatctggatt tagctaatga gattattcat cgtaataaac cagaaatgga
      181 aaaagaattt gcaggattta ctctaaatga actagaagtg attgaacata tcgggaaaat
      241 ccctgatcct aacgtgacaa aattagcgaa tgctagttac atgactagag gagccatcag
      301 taagctaaca aaaaaactga tagctagagg gatcataaac acttatcaaa gcgaagagaa
      361 taaaaaagaa atctattttc aattgacgcc aatcggacaa aaaataagga atagacacga
      421 gcaactccat caaaaatggg tacagcgaga tgctactgta tttgaaaata tgtcaaaaga
      481 agaatttgac acagtatttc gttttatcgg tcgatacaga gaatttatac gaagtagcaa
      541 atgaagctac tattttttat tgtagtgata ataggcaaaa atcataagca aaaatccgaa
      601 taccgtcgga agaaatggtg ctgcagcata aagctgtcct gcgattagcg ggccgatgac
      661 gcgcgataga gattgtatac tttgggtacc gcccattaca agaccttgct ggttatctga
      721 gacagaattg gatagttggc cattgaatac aggagtaaaa atagaatcac cgaaaccata
      781 acagataatc ccaaataaaa acaaaatcgg cagtagaaga attccagata atgtgatgaa
      841 tagataggcg aggatttcac tgaacatccc tattcttgtg atctgctgtt ctgaaaattt
      901 tttgagcaat cgaggcataa tgaacaattg cgagacagta tccaagattc caatcaaaga
      961 gaagcttaaa ccaaccaacc cagccttcca ctgaaaggcg tcaatcgaaa attgagaaaa
     1021 gatagattga agagagccag ctgccaacca aacagcaaaa cctgctgtca ataaaggaat
     1081 aacggatgaa atcttgaata attgttgtaa ttggtgaaaa ggtcttacat gggagaaact
     1141 taaatctact gaacgttttt ttattggaag gctttctagc ataaatgtgt agccataaac
     1201 ggcatttaag aaagtaaaga gtgctccaat aaatatagga acagaattcc ccaactcagc
     1261 taatagaccc cctataatag gacccagcgt tgttcctata ccgactaaag cacccatcca
     1321 tccaaaaact ttggttcttt cattaggttc cgtgatgtcg gcaaagtaag catataaggt
     1381 ggagatttct cctgccgtca atccttcaat gatacgacca aggaacaaca tccatatcga
     1441 atttcctaaa ccaaaaagca aatatccgat acttgatcct aataaactga taataaggat
     1501 cggatgacgc ccaaaatgat cacttaagct accgagaatg ggggcagata agaaggcagc
     1561 tagagcataa acagacatga gcaaagtgat atagaaagct tgctgatgta tggagtgaga
     1621 ataaggcagc gttaaaaacg gaagtacagg actgacgata gtaaatccta atccagtgaa
     1681 taagacagag acgtatccaa aaactttaga atgtttattt gtgaaactgt acatgtaaaa
     1741 actcctttat gcaataatgt taacttggaa acaaaaatag tgtatagtaa ttttgtttcc
     1801 ttgtcaacat tctaaggaac agcgaaatct acttaattta tttattccga aaagtgaaga
     1861 tacgcatcaa aaacatgaac aaacaaaaat caagtagacg acattgtaaa tctgaccgat
     1921 cagtgaagta aatagaaaag aaacctgttc ttgcttccca tgtttttttt acgtatactg
     1981 tgattgagcg gaggagaaat catgttgaat ttagaaaatt acttaagcgc tggacaaaca
     2041 gtcatatcta atcttttact taaaaattat cataggatcg gtctacaatc tgaagaattt
     2101 ttatttgttc tacagttgca tatggcacag cttgaaggag atactttccc tgatttgcag
     2161 atgattgcta tggatatggg aatcaaacaa gatcagattt ttcaaatact ggatcgtctc
     2221 gtaacaaatg gatttatcaa gatagaaacg acgattgtca acggtaaaaa agcagatcga
     2281 tataatcttt accccatcta tgatctatta ggtgagtatt taaaaacaca agaaaaaaaa
     2341 tacgaagaaa aaacacaaga aaaagaaatc cagtcagtgt atcaattatt tgaacaagaa
     2401 tttggacgcc cgctttcttc gatcgagttc cagcggatcg gacaatggct agaagaagac
     2461 cattatcagc cggaaatttt gaagctagca ctgcgggaag ccgtattaaa tcaggcttat
     2521 agttttaatt acgttgaccg cattttgcta tcgtgggaaa gaaaaaatct acgtacaaaa
     2581 caacaagtgg aagaagacca aaaacgaaga aaacagcagc ttcttcaaag agaagtagaa
     2641 cagtcagctc aacaagaaga attgccgaaa gtctcactga aaaattggtt ggaggagtag
     2701 cggaatatgt taagcaaaca aaaaacaatg gaagctctag aaacgatgta tggaatgttt
     2761 cccgaagcac atggagaact caagcacaat aatccatttg agttattgat tgcagtgatc
     2821 ttaagtgccc aggcgacaga tgtatcagtg aataaagcaa cgccagattt gtttgcctct
     2881 tttccgacac ccgatgcgtt agcagaagct tcaatcgatg aaatcattct taaaataaaa
     2941 acgattggtt tgtatcgaaa taaagcaaaa aacatcaaag cgtgtgcaca gcagctgatt
     3001 gaacgtttcg atgggcaagt gccaacgtca agagaagaat tgatgtctct tcctggtgta
     3061 ggcagaaaga cagcaaatgt cgtattgggg gatgcattcg ggataccagc aatcgcagta
     3121 gatacccacg tggaacgtgt ctcaaaacgc ctgaggatct gcaaactaga tgctacggtc
     3181 atggaagtag aagaaacact gatgcggaaa gtaccacaag aattatgggt aaagacacat
     3241 catacactga ttttttttgg tagatatcat tgcacggcaa gaaatcccaa gtgcgaggta
     3301 tgtcctttgc tatcaatatg tcaagatggg aaaaatcgga tgcgtctaaa agaaaaggcg
     3361 ctaaaaaaga aaccacgcct gtagacgtgg tttctttaat tgcaaataaa tgtatgaatt
     3421 atcttgttat tatggagaaa agctgtttcg tttatctttt ttgcatgaaa aagtaaatgt
     3481 acatactcag tagctaggat ggtaacttat tacaatttat tgcgataaaa ataaaagttg
     3541 ttatttttat tgggaaaata cccgatgtag aaaataatgc cttccaatat acctataaaa
     3601 taagtccagt attccaaagg attatataaa taagtgacgt atctatctaa aggtgtaata
     3661 aaaatgataa gtgataataa aaaaatacca tttataacta aacataaact aatggatttg
     3721 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
     3781 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
     3841 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
     3901 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
     3961 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
     4021 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
     4081 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
     4141 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
     4201 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
     4261 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
     4321 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
     4381 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
     4441 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
     4501 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
     4561 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
     4621 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
     4681 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     4741 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     4801 acgattctga agtgacaggc gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     4861 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     4921 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     4981 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     5041 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     5101 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     5161 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     5221 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     5281 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     5341 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     5401 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     5461 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     5521 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     5581 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     5641 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     5701 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     5761 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     5821 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     5881 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     5941 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     6001 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     6061 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     6121 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     6181 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     6241 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     6301 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     6361 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     6421 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     6481 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     6541 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     6601 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     6661 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     6721 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     6781 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     6841 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     6901 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     6961 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     7021 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     7081 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     7141 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     7201 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     7261 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     7321 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     7381 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     7441 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     7501 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     7561 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     7621 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     7681 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     7741 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     7801 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     7861 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     7921 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     7981 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     8041 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     8101 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     8161 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     8221 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     8281 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     8341 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     8401 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     8461 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     8521 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     8581 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     8641 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     8701 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     8761 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     8821 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     8881 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     8941 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     9001 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     9061 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     9121 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     9181 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     9241 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     9301 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     9361 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     9421 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     9481 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     9541 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     9601 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     9661 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     9721 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     9781 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     9841 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     9901 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     9961 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
    10021 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
    10081 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
    10141 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
    10201 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
    10261 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
    10321 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
    10381 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
    10441 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
    10501 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
    10561 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
    10621 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
    10681 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
    10741 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
    10801 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
    10861 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
    10921 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
    10981 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
    11041 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
    11101 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
    11161 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
    11221 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
    11281 ttcattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
    11341 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
    11401 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
    11461 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
    11521 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
    11581 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
    11641 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
    11701 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
    11761 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
    11821 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
    11881 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
    11941 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
    12001 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
    12061 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
    12121 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
    12181 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
    12241 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
    12301 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
    12361 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
    12421 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
    12481 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
    12541 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
    12601 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
    12661 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
    12721 tggcaggaga acaccgttta tt
//
LOCUS       DAFLWZ010000072        12732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000072 DAFLWZ010000000
VERSION     DAFLWZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.074"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1V38_002239"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1V38_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1316775.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="L1V38_002240"
     CDS             complement(322..891)
                     /locus_tag="L1V38_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBN1316776.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="L1V38_002241"
     CDS             1077..1979
                     /locus_tag="L1V38_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1316777.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1V38_002242"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1V38_002242"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBN1316778.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1V38_002243"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1V38_002243"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBN1316779.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1V38_002244"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1V38_002244"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBN1316780.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="L1V38_002245"
     CDS             8547..8732
                     /locus_tag="L1V38_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBN1316781.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="L1V38_002246"
     CDS             complement(8794..9990)
                     /locus_tag="L1V38_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1316782.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="L1V38_002247"
     CDS             complement(10160..11596)
                     /locus_tag="L1V38_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1316783.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="L1V38_002248"
     CDS             11889..12698
                     /locus_tag="L1V38_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1316784.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2672 c         2250 g         4009 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt ga
//
LOCUS       DAFLWZ010000073        12432 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000073 DAFLWZ010000000
VERSION     DAFLWZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.075"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..190)
                     /locus_tag="L1V38_002249"
     CDS             complement(<1..190)
                     /locus_tag="L1V38_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316785.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="L1V38_002250"
     CDS             complement(200..1015)
                     /locus_tag="L1V38_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1316786.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="L1V38_002251"
     CDS             complement(1277..1720)
                     /locus_tag="L1V38_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBN1316787.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="L1V38_002252"
     CDS             complement(1854..2192)
                     /locus_tag="L1V38_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1316788.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="L1V38_002253"
     CDS             complement(2180..2557)
                     /locus_tag="L1V38_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1316789.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="L1V38_002254"
     CDS             2781..3974
                     /locus_tag="L1V38_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316790.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="L1V38_002255"
     CDS             complement(4140..4562)
                     /locus_tag="L1V38_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1316791.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="L1V38_002256"
     CDS             4957..5151
                     /locus_tag="L1V38_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316792.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="L1V38_002257"
     CDS             5148..5594
                     /locus_tag="L1V38_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316793.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="L1V38_002258"
     CDS             complement(5804..6976)
                     /locus_tag="L1V38_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1316794.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="L1V38_002259"
     CDS             complement(7182..7997)
                     /locus_tag="L1V38_002259"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1316795.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="L1V38_002260"
     CDS             complement(8147..8593)
                     /locus_tag="L1V38_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1316796.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="L1V38_002261"
     CDS             complement(8590..9594)
                     /locus_tag="L1V38_002261"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1316797.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="L1V38_002262"
     CDS             complement(9634..9963)
                     /locus_tag="L1V38_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1316798.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="L1V38_002263"
     CDS             complement(10089..12416)
                     /locus_tag="L1V38_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1316799.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3513 a         2430 c         2272 g         4217 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aa
//
LOCUS       DAFLWZ010000074        12359 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000074 DAFLWZ010000000
VERSION     DAFLWZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.076"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..465
                     /locus_tag="L1V38_002264"
     CDS             <1..465
                     /locus_tag="L1V38_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1316800.1"
                     /translation="WKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAF
                     LKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVK
                     RRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPD"
     gene            complement(1081..2121)
                     /locus_tag="L1V38_002265"
     CDS             complement(1081..2121)
                     /locus_tag="L1V38_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1316801.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2470..2796)
                     /locus_tag="L1V38_002266"
     CDS             complement(2470..2796)
                     /locus_tag="L1V38_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316802.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2783..3586)
                     /locus_tag="L1V38_002267"
     CDS             complement(2783..3586)
                     /locus_tag="L1V38_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1316803.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3939..4229)
                     /locus_tag="L1V38_002268"
     CDS             complement(3939..4229)
                     /locus_tag="L1V38_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1316804.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4365..4544)
                     /locus_tag="L1V38_002269"
     CDS             complement(4365..4544)
                     /locus_tag="L1V38_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316805.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4541..4891)
                     /locus_tag="L1V38_002270"
     CDS             complement(4541..4891)
                     /locus_tag="L1V38_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316806.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4884..6209)
                     /locus_tag="L1V38_002271"
     CDS             complement(4884..6209)
                     /locus_tag="L1V38_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1316807.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6659..7273
                     /locus_tag="L1V38_002272"
     CDS             6659..7273
                     /locus_tag="L1V38_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1316808.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(7438..7680)
                     /locus_tag="L1V38_002273"
                     /pseudo
     CDS             complement(7438..7680)
                     /locus_tag="L1V38_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7884..9203)
                     /locus_tag="L1V38_002274"
     CDS             complement(7884..9203)
                     /locus_tag="L1V38_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBN1316809.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(9358..9945)
                     /locus_tag="L1V38_002275"
                     /pseudo
     CDS             complement(9358..9945)
                     /locus_tag="L1V38_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10583..10840)
                     /locus_tag="L1V38_002276"
     CDS             complement(10583..10840)
                     /locus_tag="L1V38_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1316810.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10833..11102)
                     /locus_tag="L1V38_002277"
     CDS             complement(10833..11102)
                     /locus_tag="L1V38_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1316811.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(11233..11412)
                     /locus_tag="L1V38_002278"
     CDS             complement(11233..11412)
                     /locus_tag="L1V38_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316812.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(11793..>12359)
                     /locus_tag="L1V38_002279"
     CDS             complement(11793..>12359)
                     /locus_tag="L1V38_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316813.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3787 a         2257 c         1894 g         4421 t
ORIGIN      
        1 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
       61 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
      121 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
      181 gataaagcac catcaattgc tagtgccttt aagaaactaa aagaatacgg attttatcaa
      241 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
      301 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
      361 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
      421 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag attaaatcat agataccgta
      481 agggatttta ttctttattt aaaactttgc aacagaaccg tccgttgcgg gtaataccgt
      541 aacactgaag ggcacgcatt aaggcgtcat cttaatgctt tcctgtagga cactgacgga
      601 gattaccagt ctcccgagcc ttacaggggc ctttcttttt tttgtatttt caattatcac
      661 aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc acaagcatat cagacaatta
      721 aatttaaaac aactaaaaat atacaaaaaa gtgtaattga atattagcag cactgcctga
      781 aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt gaattacctc tcttcatgaa
      841 ttattataac tcaaaaaagc acatatgcaa acactagttc cctatttttt tgaatgaaaa
      901 ataactaaaa tatctaacga ttatgacttt aaaacctacg tttgtgattg ttttcataaa
      961 cttttaatct aaaaactccg gaataatagc tatttatttg taacatttgt aataaaatta
     1021 aaatcataaa aaagttctaa tttaaaattg atcattttta tagtgatcgc tttttatcaa
     1081 ctactctagc caattttccg tactaactgt tggtaattcg ttaaatgttt ctctttgttc
     1141 gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa ttttttacat aaacgaaaat
     1201 tagattctgc aaattgttta ctttttcagt tttttgtttt tgataagctt tcagcaaagt
     1261 catatataat cctttgtcag catcaattcc ataagattcc agttcttcat aaacaacaac
     1321 tgtttgctct aattcttcag cttttttctt tgcattatga atagtttgga cggttttttg
     1381 agcgtcttcg taagtactag aaaatgtttt tatcaagttt aatacatttt ctggtacaaa
     1441 tgtatttata ctgtcctctt tcatgatgtc gacgaagtta tctagtaaaa cttgattttg
     1501 taactgatca gtttcagtgt ctattatgtg tctattagtg tctatagaat tagaatagaa
     1561 tagattgtct gcgattttcg caattacggt tgagtccttg atatgactgg attttgccgt
     1621 atttgcgatt ttcgcaatta cggtggtatc attgatttct cgcggttttg ccgtatttgc
     1681 gattttcgca attacggtgg tatcagtatt gtcttcctct tccatgattt taaagacgtc
     1741 ttgattcgtt acttctggct tgcctaagta caataaatta ggcatggatt caatcttacc
     1801 gtcacgttta tttactcttc ctctcttctg tttcagaaga cctgcttttt ctaattcctt
     1861 tttgatttta gatactttac cttcgcggca ttgtaacaat ttcattaatt cttcaactgt
     1921 gaatatgaaa aatatattat catcagaatc tacccagtta tttttgactg aataatcaaa
     1981 tcgatcttta agtagcatat aagcaatttt tgcatcattt gatagatcca tgtatttttc
     2041 gttagtaaaa aataccttag gcatttgata atatttttca cgataaattt cttttgattt
     2101 gtaataatta aaatcattca tagccaatcc tctttctgta ggatagcgtt ttgttcaaaa
     2161 ctatgttaca atgaattaaa caaatatatc tatccactat atatttttct actgctgata
     2221 agtcgccaaa ctttgttaaa gcagtagtct ttttttatct ttttttagtt taccttaaaa
     2281 aataaattaa agcaaaccgc tctatttcaa ggtttaagct catagtaact atatcacgat
     2341 attacaataa tattatatca cgatatcgta atattacaat atgaagataa gcgacttatc
     2401 agctttgata ctactgattt ttataaaaaa aatatcacga tattatgata tcgtgatatt
     2461 gaatgtaaat taaattttat tttgtttctt tgctagttta tatccttcaa tcaagtattc
     2521 ttcaggtatg gactttaata gcgcatcttc tataacgtct ggtttacttt tgtctgattc
     2581 agcaatagtc gtccaatatt tgagtgctga cattagaatt ggatttatac gaatgctatc
     2641 tgctgttctt acactacttc cttgatcttt tatgacttta cttatatttt tcttggttaa
     2701 ttcgatttct tctacttctt ttgatttaaa attcttttta tttttatttc ctagtaatct
     2761 acttactgca gcttgactgc gattatcttc tgccatcaaa atcaccaact tcttttaaat
     2821 attcttctgt aaatgcttta tagtcatctt cagctgttga gggtttatta aaattgatta
     2881 gatctgatcc agcagcttgc gcttcgtcaa cggttattgt cctacgaata taagttttga
     2941 aaatttttgc accaatgact ctagaaattt cggttgctgc agacgtcatt tctttagaaa
     3001 tgttataacg cttattatac ttagtaaata gaactcctcg tacttcaagc ttgtcgttcg
     3061 tatattcttt taccgtttca atagtttcac ttaactttat tagtcctttt aatgagaaat
     3121 acgcagcttc aactggaatg ataatttcat cagaaacagt aaatgcgttg actgtaagca
     3181 ttcctaaact tggtggacaa tcaattataa tataatcata gttgtccttg attggttgaa
     3241 gtactctttt aagcctgtgt tcacttccta cttgagtaaa ttccctctct gcagaagaaa
     3301 gggctatgtc ggctggcaaa acatcaattc ctttatagtc cagaatagca tctgtaatgt
     3361 cagcctcccc ttttaatact tcataaattg taggttggtt tgttccatct atatcgaaac
     3421 ctacattatc tgtagcattt ccctgaggat caatgtccac taaaagtaca tttttaccgt
     3481 aaacaaattt caaacatgct gctaaattaa cgctagtcgt agttttagaa actccacctt
     3541 tttgattggc tactgacaat attcttgcca ttaaaatatc ccccattcat cttatattat
     3601 aatataatta tatcataata ttgtgatatt gcaatatcgt atatgcatta tattgtaata
     3661 ttgtgtgatt attttgtttt aaagatatat atcggttcgg atataaagat tattcatatg
     3721 ttattcgaaa ttaaaataat cactttttat tactttaaaa ttttttatta atgataagaa
     3781 atatgttttg cgagcagcaa ctagaataat ttaaacatta ctaaactgtc tatattgtta
     3841 ctaataattc ccttcttata gtgcattttc ttagaaaaaa acaatattac gatatcatga
     3901 tattaagata tcgtaatatt atacaattgt gattgatatt atatatgttt ttttattttt
     3961 ttatcatgtt taatcttgaa ggaatcatat tctttttcta aagacaggag cttttcataa
     4021 acatcagaca tgtttaaact agaggccagg cttaaatcat aaacgaatga agcaggtaat
     4081 gattttattc tacgttgtcg ggttatccag cttgcaaccg ttccttgtgg gtaggcatat
     4141 aactcacaaa attgttctac agtgattcct aaattcttga taatgtaaac attgatcggg
     4201 tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc ctactttctt ttattattgc
     4261 gtttgcaata atagtttaac acacgcatta ttctagtatc tactcctatt tgtaaaaaca
     4321 aaaaaggatt catagagata actctataga atccgtaaaa taccttatat atataacggg
     4381 aagatataaa acctaaaatt atgataacct gctgcagctt ctacatagaa agagaagcgc
     4441 tcaacaccaa cctcatttat caaacgttgg ccataacccc aaatctcttc tgatagctga
     4501 tcaaaggtta tatactttag ctcatattgc tggataatgt tcattctaat cgactccatt
     4561 tattatcctg gtaaaattcg atatgacgta tttcgtcgta gtgaattttg tcttttccaa
     4621 cgtagatccc cagctcatca ctacctaaga tcttgccaat gatatcttct ggatagtatc
     4681 cttcagcgtt tcgttcttct ttttgaatag atactgatct attttttatg actgcagcgt
     4741 tcaatacttc cgcaatctct tcagtcgtca tttgttcttt tgctaaattt tgactggttc
     4801 gttgttcatt gtcggcatca atttcttcag tatgatcaga taaataaaac cctgcccact
     4861 ttaaacgtcc acgatcattg taatcaatca tttttaattc ccccatttcc gcccgcatga
     4921 ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt ctaacattga agaagcatgt
     4981 acaatcgacg taaaaccata tttttgccga atcttgtcaa taattttatc taaattttct
     5041 tcgtcaattt gcttttgtgg atcactaaat aaatccagct gaagcgaatc ggtgtacaca
     5101 agcttgctat aggttattcc aacatgcctt acttcttgtc cttcataata cttatcaaac
     5161 aagaaaagac aataattctg caattccttt gtattatctg tgatagggat cttcatctgg
     5221 tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa tgtgtaaatg gacacaacct
     5281 gttttacagt tatgctgcct aatgcgtatc gctacttgtt ccgccatttc ttttaccacc
     5341 agctcgattt catttcttct agtataatct cgtggtaaca cttgtgaatt tccatatgat
     5401 ttttcctttg tcggttctgg tgggattgct atatctgttc gatcgatccc attagcatgg
     5461 aagtacagct gtaagccaat cacacctagt ctattcttaa tcgtataagg attccagtta
     5521 gcaagatctc taatgctcat aatccccatc tgattgagtc tttttttcat tcgagagcca
     5581 attccccaaa agtccgtcat ttcaggaata ttccatactt tttcaggaac gttttcgtac
     5641 gtccattccg caacaaatcc ttcattatgc tttgcttcgt tgtctaaggc tagtttagcc
     5701 aaaaggggat tatctccgac acctactgta gcaatcaatc ctagctcttc tttaatattc
     5761 tcctggatca tttgagccag cttctttctc cgttgacttc gtgttccttc agtcgtaaaa
     5821 agattcagtg atcgggtcac ttttaagatt gattcatcga tcgagtaaat cagtagatct
     5881 tcatcagcca catatcttct gaaaatatta tttacctgca tatttcgctt gatatatagg
     5941 ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg gttgtggtaa gtcacgtggt
     6001 ctactcacat ttgtaatacc ataccgcttt tttgcttcag gagaagaagc taatatcaat
     6061 cctgaaccag tattatcagc tcgactcata acaacaagtt ctgttgttaa tggatctaaa
     6121 tttctttcta tacattcgac acttgcgtaa aagcttttca tatcgattaa aaagtaatca
     6181 tttactggct cttttgaata atccatcata aataacactc cattctttca cattatacaa
     6241 acatatgttc gatattgtaa agaagaaata gctaaataca taaaaaaaga agcataggta
     6301 tgctatcacc ctgcttcttc ttttgatttg tatgatcaat ttattctatc actttactaa
     6361 ttaatttgaa aatctaataa aaactctcac tctaaaagag tgagagactg caaattagag
     6421 tacggacttt tttggagttc cgttctttaa tattaacaaa tgaataaaat ccttacaaca
     6481 tttgagaata agttatcagt agacacttac aaaaaattct catactattt cctccatcat
     6541 tagtttttgt ctatataagg tttaccctaa atagacactg gtataacatt gaaaaatatg
     6601 gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg taaaagtttt
     6661 gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc agattgaaga
     6721 aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg caacgattac
     6781 tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata tttttattgt
     6841 ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag tcaattactt
     6901 gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg aagcaattgg
     6961 caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg ccatgatcgc
     7021 tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga tcgcaaaagc
     7081 aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag atccccaacg
     7141 tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga ttgctaagat
     7201 tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag acagcatggt
     7261 caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat ttcctacata
     7321 taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa attccaacaa
     7381 accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt atttacgtta
     7441 atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct tattatcttg
     7501 tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa ttcctatagc
     7561 tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt gagatttatt
     7621 tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca taaagctatc
     7681 cctgaataat tcatagcttt aattctttgg cacattttat tgaaatatgt atcactaata
     7741 tccctatcaa ctgattttga ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg
     7801 aggaataaat tttgggtgta aggcattttg agcatacttc tccctggata acttcccagt
     7861 aaaaaaatcg ttagattgtt ggattagatc cattgactgg ctcgcctcag gcgagcaaag
     7921 accctgtaga attcattctg atacacatga taactagata atttgagata gactcgtcta
     7981 cccgtttgga ctaatttccc agcaactttc agaaacttca atcgaataga atgaatggtc
     8041 attccctttt ggacttcttc aaagccaatc gttcttaaga agttgactaa gttgtaagct
     8101 atcaagctga gcatcattcg gacatgattc tccaaaaagc gaggactgtc tgttttgtca
     8161 aagtaaaagc cagctttcgc ttctttaatg aagttctcca ttgtgccacg tttggcatag
     8221 atagaaaaga tggtatcagg agaaacattt tctgatagat tcgtcacgat aaattcatgt
     8281 cgaaagagca gttcgcccgc ttcacgtgtt gagcgtatac acacgcgacg actttgtgac
     8341 caggattgtg cttgataagt ggtcgagaag tactgaactt ctcgttcttc ccacttttga
     8401 ttatcgccat aaagtactga tttctcagct atttgaccta gtctacgatt attcttcagt
     8461 cgaataacat aatgactctt ttttgattca cacgaatcat acacaccagg tgtagcgaac
     8521 ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag agtgattata gtgctctaat
     8581 aaaggtgtga gaaactcctt tacgcctttt gatgtatatt gatttcctga acgtagttca
     8641 gcttttaaga agtcaccagt caatccgtca aaagctacca atggatggta accataggtt
     8701 tggtagtgtg tattataatt cgtttgttct tggtgaccaa atgtatctga atgggtcgaa
     8761 tctaaatcaa tgattaattc cgtatcatta cggatgaggc gtgctttatc gataagttct
     8821 tggttcaaag cttgaagttc atggatattc tcctcagata gtcgatctaa aaatcgggaa
     8881 agtgaagatt gagaagcgag ttctttccta tctaaaacag ctttaaacac aggatcttgt
     8941 ctcaggagat tagctgcaga atcagctgag taaccagcaa ttaattgcat aatgaactgc
     9001 tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt
     9061 tgcttagcca gttcagaaaa accaaagatg ttcatcagct ctttcactag gacgagaccc
     9121 gaatcactcg ataattgacc acctgtatga gaaatagtga tatttgaatt gaattttact
     9181 tggtttttgt gtaagctagt catgaaaaga actcctttct tttggttggt ttagtcactt
     9241 taaccatagc agaaaggggt tcttttttca tcacttaacg ggtgaagatg aaaaagtaat
     9301 tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa aagtatgaat tattcaggct
     9361 atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac attcaaaaca
     9421 ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac gtttttctat
     9481 gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt accctttaaa
     9541 catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata ttagagttaa
     9601 atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg taattatcga
     9661 aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta taagagaaaa
     9721 ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag aagttatatc
     9781 tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa tttctatcca
     9841 attactatct tctaatctgt atatgctcga agtataattt gattcgtcag caagcatcgc
     9901 tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag caatattgct
     9961 aaaatcagct aatttttctt tagaataaaa aaaaacattt atatcagaat caataaattc
    10021 tattttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
    10081 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccaata
    10141 tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta atttttagct
    10201 aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact agtacaaaaa
    10261 atttaaaata gattattaaa cctattgctt attctattca gtcatatata taagcgtcat
    10321 cctttagtaa ctaacatccc acactacaat agtattataa catatctatt caacttcaaa
    10381 ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg attttactaa
    10441 ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac actaagctat
    10501 attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt aagtttctga
    10561 ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata aatatcgttt
    10621 cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac cattttccag
    10681 ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa cgatcgatat
    10741 cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca tgccaataaa
    10801 gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac ctcgattaag
    10861 tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat tttttccatg
    10921 acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc tctttttgat
    10981 aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc agcatcctca
    11041 ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc tactgcttcc
    11101 attcctttca ccccttattt atttctataa aacaattgta cattatattg tacaattaag
    11161 caaatgatta atattctaac ttcttataat taaaagtgct atcactttta gtttttagga
    11221 taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt cttgggcaat
    11281 caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact tctgctttag
    11341 ttgctgcaat tctttttgtc tcttttcatc caacgtaacg ggtaaccgtt tatttcctat
    11401 tgcaattggc attagtactc tctcctttca tcgaaataac cctatgaaaa atatggctgc
    11461 aatcatcttg aatagtagac tcacaagggc taatacaaag cgccaaaaga tcaaacaaaa
    11521 taccagtatt gccaaaaata ctacgaagtt taaatgcaca gctgcagcat ggcgcataag
    11581 tatttcgcca acaaatagga ctaacaatag aggaatgatt ttattcatat ggatctcctt
    11641 ctttctctta ggttatcggg tgttgcccgc ttatttcgca ccacctaagc ggcgggggcg
    11701 gttggagcga ttggtgcgaa ataagaacca ttcccttagt tactaggttt tttgtcctta
    11761 tttcacacat tctcactttt cggtataaat gattattgcc tttttttcct ttcaaatcgt
    11821 tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc gtcgtaagta
    11881 taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt atctacttct
    11941 tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat tcccattaac
    12001 acgatagatt ccgttccaca cgtcaaaaat ctagtaaata caaggtaata atcgtctatc
    12061 gtcgcatctt tgctgtttag ctcttccatt tcttcttcca ttaattccat gctctcaaaa
    12121 attgaataat attctgattc tgagtaatag tgtttcctgc aaatcgtgta gctgacaaag
    12181 ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc tgtttctagt
    12241 cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac gtctaaacga
    12301 ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa ttgttcttc
//
LOCUS       DAFLWZ010000075        12225 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000075 DAFLWZ010000000
VERSION     DAFLWZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.077"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(63..620)
                     /gene="frr"
                     /locus_tag="L1V38_002280"
     CDS             complement(63..620)
                     /gene="frr"
                     /locus_tag="L1V38_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBN1316814.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(623..1345)
                     /locus_tag="L1V38_002281"
     CDS             complement(623..1345)
                     /locus_tag="L1V38_002281"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBN1316815.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1481..2362)
                     /locus_tag="L1V38_002282"
     CDS             complement(1481..2362)
                     /locus_tag="L1V38_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBN1316816.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2461..3243)
                     /gene="rpsB"
                     /locus_tag="L1V38_002283"
     CDS             complement(2461..3243)
                     /gene="rpsB"
                     /locus_tag="L1V38_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBN1316817.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3602..4081
                     /locus_tag="L1V38_002284"
     CDS             3602..4081
                     /locus_tag="L1V38_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBN1316818.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4298..5389
                     /gene="phnW"
                     /locus_tag="L1V38_002285"
     CDS             4298..5389
                     /gene="phnW"
                     /locus_tag="L1V38_002285"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBN1316819.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5382..5510
                     /locus_tag="L1V38_002286"
     CDS             5382..5510
                     /locus_tag="L1V38_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1316820.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5514..6059
                     /locus_tag="L1V38_002287"
     CDS             5514..6059
                     /locus_tag="L1V38_002287"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1316821.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6513..8204)
                     /locus_tag="L1V38_002288"
     CDS             complement(6513..8204)
                     /locus_tag="L1V38_002288"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBN1316822.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8624..9571)
                     /gene="arcC"
                     /locus_tag="L1V38_002289"
     CDS             complement(8624..9571)
                     /gene="arcC"
                     /locus_tag="L1V38_002289"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBN1316823.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9686..10705)
                     /gene="argF"
                     /locus_tag="L1V38_002290"
     CDS             complement(9686..10705)
                     /gene="argF"
                     /locus_tag="L1V38_002290"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBN1316824.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10796..12025)
                     /gene="arcA"
                     /locus_tag="L1V38_002291"
     CDS             complement(10796..12025)
                     /gene="arcA"
                     /locus_tag="L1V38_002291"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBN1316825.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3350 a         2533 c         2205 g         4137 t
ORIGIN      
        1 aaagaaatat aaataaaaac agaggaagcg gaatgatccg cccctctgtt tttatgattt
       61 tattaaactt ccaataattc tttttcttta tcagcagcga tcttatctac ttctttgatg
      121 ctgttatctg tcaatgtttg tacgtctttt tctaatccgc gcaaatcatc ttcggtaata
      181 tcaccatttt tttgttgttt tttatattca tcgatcgcat cacgacggat gttacgaatc
      241 gcgatttttg cattttctgc ttctttttta acatctttag ctaattcttt tctgcgttct
      301 tctgtcagtt gcgggataac taagcgaatg acatttccat cattggttgg actgattccg
      361 atatcacttg ccataatagc tttttcaaca tcttgaagaa tgctcttgtc aaaaggtgtg
      421 atcattaaaa cacgtgcttc tggaatttgg attgatgcca tttggttcaa tggtgttggc
      481 gcaccgtagt agttcacagt aatacggtcc aaaaggctag cgttcgcacg gcctgcgcgg
      541 atttgcccaa gttcacgttg aagattttgt gctgcttttt tcattttttc ttttgcttct
      601 gtcataattg catctgccat ttttatttcc cccttacagt tgttccgata ttttcgccta
      661 agattgcacg gcgaatattt ccgtgttcat ttaaattgaa gacaagcagt ggaatatcat
      721 tatccatgct tagtgaactt gcagttgaat ccatgacttg taatcctttg gcaataactt
      781 ccagatgagt cagttcttca aattttactg catttgcatc tactttcgga tcagcagaat
      841 aaacaccgtc tacattgttt ttagccatca ggataacatc tgcgccgatt tctgccgcgc
      901 gtaatgctgc tgttgtgtct gtcgagaagt acgggttgcc ggtaccgcct gcaaagataa
      961 cgatccgtcc tttttctaaa tgacgttctg ctttacggcg aatatatggc tctgcgattt
     1021 gacgcatttc aatcgaagtt tgcacgcgtg tcggtacacc cacgttttcc aacgtatcct
     1081 gtaaagctaa ggcattcata actgtagcta acatacccat gtaatcagct tgagcacgtt
     1141 ccatgcccat ttgtgctccg atttgtccgc gccagatatt tccgccgccc acaacgattg
     1201 ccatttcaac gcccagctcg tgaacttctt tgatttcttg gatgatttct ttgattactg
     1261 gtggtttgat tccaaatcct gcgtccccag ctaaagcttc tccactcaat tttaagacta
     1321 cacgctgata tttcggtgtg accatgttca ttcctccaat attttctatt gccattttac
     1381 catacttaga tgatttcgac actctaagac tggtttttct tgttttgctt aaaaaaaggg
     1441 agcgcacaaa ccgtgcgttc ccgtctgtta ttcaacagaa ttattttttc acttggctca
     1501 taacttcttc tacaaagtta tcttcgcgtt tttcgatacc ttcgccaact tcgaaacgta
     1561 cgaatgtttt aacagttgcg ccttttgatg caacgtattt ttcaacagtc atatcaggat
     1621 ctttaacgaa tggttggtcc accaaagcga tttctgcttt gaatttcttc aagcgtcctt
     1681 ctaccatttt ttcaacgata ttcgctggtt tgccttcgtt caatgcttgt tctgtaagaa
     1741 cagttttttc atgttctaat tcagcttctg gaatttgtga ttcgtttaca taacgaggat
     1801 tgatagctgc tacgtgcata gctacgtctc ttgcaactgt ttcgtcagtt gttccatcta
     1861 gaacagtcaa tacggcaata cgtccgccca tatgcaagta tccaccaaat gcagcattgt
     1921 cgtctttttc tacaacttca aagcgacgga agctgatttt ttctccgata acttgagttg
     1981 cttcgatcaa gtcagattca attgtacctt tatctgtttt gattttcatt gcagcttcca
     2041 tgtctgctgg tttgttttca gcaacaagtt ctgcaatttc ttttactaaa tcttggaaca
     2101 tttcgttttt agaaacaaag tctgtttctg agtttacttc aacgattgct gcagtgttac
     2161 ctttcacagc aactgaagcc aatccttcag ctgcaatgcg gtcatttttc ttcgcagcct
     2221 ttgccattcc tttttcacgt aaaagatcaa ctgctttttc catgtcgcct tctacttcaa
     2281 ctaatgcttt tttcgcatcc atcattccta cgccagtcat ttcgcgtagt tcttttacca
     2341 ttttagctgt aacgtctgcc atgtttaact cctcctgtgt gtttttcttt ttaaaaaaag
     2401 ctgcttcaaa ggagagtgag gcttgtcgcc cagcctttga aacagctcca tcattcaaaa
     2461 ttattctgct gaagaattgt cgccttcaac aacatctacg atttcttcga ttgatgttgc
     2521 tgtgttttct tctgtgaaat cttcttcaac tacttgatct tcaccttggt ttccttcgat
     2581 gaaagcatca gccatttttg aagtaatcaa tttaacggca cgaattgcat cgtcgtttga
     2641 agggattact acgtcgattt catctggatc gcagtttgta tcaaccatag ctacgattgg
     2701 gatatttaat ttgtgtgctt cttgaacagc aatacgttct ttacgtgggt caacgatgta
     2761 cattacatct gggattcttg gcatatcagc gataccgcct aagaattttt caagacgttc
     2821 acgttctttg ttcaaaccag caacttcttt tttaggtaga acttcaaaag ttccatcttc
     2881 ttccattgca ttgatttgtt tcaaacggct gatacgtttt tggatagtat cccagtttgt
     2941 caatgttccg cctaaccaac gatggttaac gaagtattgt cctgcacgag ttgcttcttc
     3001 tttgattgct tcttgtgctt gtttttttgt acctacgaat aatgctacgc cgccttcttc
     3061 agcaacgctc ttcatgtaat cataagctgc atctactaat ttaactgttt tttgcaagtc
     3121 aatgatgtag attccgtttc tttctgtgaa gatatatttc ttcatttttg gattccagcg
     3181 acgagtttgg tgaccaaagt gtacgccggc ttctagtaat tgtttcatag aaattactgc
     3241 catgtttgtt tcctccgatt tggttttatt tttcctcttc ttatcttcta ccttgccggc
     3301 aaactttttc aagcacctac cgacaatcca ataagaatgt ggatttgctg atgcataaag
     3361 caccctcagc tattatacag acaaaagatc cgtatcgcaa gagcaaatat acttttctgc
     3421 tcaacattca atagtttacc tgaaagataa aaagaattca agaaaaacag tagatttctc
     3481 tttgtttctt tattatcctt tttccataaa ataattttag gtataaaaga cgaatattat
     3541 tgggcaatcc ttcttttttt tgttatgata catgtgaaat ctttcgtaaa ggagaaagaa
     3601 aatgcgcaaa gctcaaagac atttgctgat taaacaagtc attgaagaat tcccgatccg
     3661 tacgcaagaa gaactattaa acaaacttgg gcattatggc gttaccgcca cgcaggcaac
     3721 gatttctcga gatatccgtg atctaaaaat cgtgaaggca cctgatgaaa atggcgtttc
     3781 ccgcttcgta ttgtttcgcg aaaaaggaac tcctgagact aggactgagg aagaggatcg
     3841 gctggttcaa atgattgaag acattgtatt gaaagtcgaa cgagtccact ttttgacgat
     3901 cgtcaatacc ttgccagaca atgctcattt atttgcatct gttttagatg agatcaaacc
     3961 tccctctatt gtcagtacaa ttgctggatt cgatacgatc atggtcatct cggaaaatga
     4021 ggaggacgca aaacgagtag aagaatttct tcaccatcca actgaagtat cactttttta
     4081 atcagagcac gtattcctaa tatggaatgc gtgttttttt attttcaata ttttccttat
     4141 tgaataaacc tttacactct ttacaaaaat acatcatttt ttattcaaat ttttcaacac
     4201 cttgattgaa tcacaataat catcatttat attggatgtt aacaagagca gcttcttgct
     4261 ctttgtgtat ttcaaaaaag aaatgaaagg aaatcatatg tataaattat taacttctgg
     4321 accattgacg acttctgaaa cagtgaaaaa tgctatgctg atcgatcatt gtacttggga
     4381 tcaagaatac aaagaaatta cacaatggat aagaaaaaaa ttattggatc ttgctcaagt
     4441 atcggaagga atatacacaa cggtcttaat gcaaggtagc agctccttcg gggtagaatc
     4501 ggtattaagt tctgtgatca ggccagaaga tactgtactg atttgttcaa acggcgcata
     4561 tagacaacga atgatcaaca tgtgcgaatg tctgaaactg aactataccg tttatgaggt
     4621 atcggaacat caaatcctcc aagctcatgt gattacacag ctgattgaag agaatccgtc
     4681 tatctccgca ctagcaatgg tccatagcga gactacttcc ggtattttga ataatttgga
     4741 agagattgct gctgtcacac aagaaagaga tcttttgttt atagtggacg cgatgtcaag
     4801 ctttggtggg ataccgattt gtgtagccga actagggatt gattttttga tttccagctc
     4861 aaacaaatgt attcaaggtg ttccaggctt ttcttttgta cttgctaata aagcggaact
     4921 ggaaaaacga aaaaatgtta gccgaagttt gtcacttgat ctatatgacc agtaccgcgt
     4981 gatggaaaac gagaatggca aatggcgttt cacttcccct acccatacgg ttttggcttt
     5041 tcaacaagcg ctgaaggaac tagaggcaga aggaggaatc gaaactcgat attcacgtta
     5101 tctcgccaat aatcatgtgc tacgacaaaa aatgacagag atggggttcc agcctttcat
     5161 tcaagaatat caggggccat tcatcacctc ttttctttac cctaaggact ggcgatttga
     5221 ttttaatcat ttttatcagt atttaaagca aaatggattt gtgatctatc ccgggaaaat
     5281 cagcgatcat gaatgttttc gtatcggaaa tattggcgag atctatccgg aagatatttt
     5341 ggaactgaca gcaattatca aagactataa ggagaacgtt aatgattaaa actgtaattt
     5401 ttgattgggc aggaacaact gtggactttg gctgtatggc tcctgtccac gcttttagaa
     5461 atgcttttct agaaaaagga atccaactga ctgacaaaga aatccgctaa ccgatgggaa
     5521 aattaaaatg ggatcatatc caacagcttc tttccctccc ttctgtcaaa aaacaatgga
     5581 tagctattta tggacaacta cctcaggaaa aagaggtgga ggaattgtat caacaatttg
     5641 aacattatct gtttaaagat ttggtcaagc attctacctt gaaacccgac acattggaaa
     5701 cgatcgaacg gttgagaaac gctgggatca atattggttc cacgaatgga tttaatgctc
     5761 ctatgatgac aatcgtagca gaaaccgcaa aaaaagaaag gtattcacca gacttcatgg
     5821 caacttttga agacgtcgaa gggtatggtc gaccgtttcc ttatatgatc cataaaaaca
     5881 tgcagtactt caaaaacaag tcggttgatg aagtaatcaa agtcggagat acggtctcag
     5941 atatccagga agggaaaaat gccggagtgt tgacagtagg tgtaattgaa ggtagttcgc
     6001 taatggggat ttcttatgat gagtaccaaa aattagagat ggggaaaaag atcgtttaaa
     6061 acagtctgtt gctcttagat tccaacaagc cggcgctgat atttgtgtaa acaatttaaa
     6121 agagttaaca gaatacattt tgtacgctga catgaatcca gaatgacttt tatacaaaat
     6181 aagaggttgt gaaaaagctg tcctgtatca agtaataaaa acagccaagc aaaaatagct
     6241 cctcatattt ttcgtttggt taggcttatt accgcagatg caagcttttg aacaccgttt
     6301 attcgaaaaa aaaaagggag ctgtgacacg acttttgtca cagtcccctt atttgcaaac
     6361 aaacagtgtt taagagacaa cctctccact aaacggtgtt cattcagctg actctcggta
     6421 tttgctcaaa aaacgataaa atttgaaaag ctattttctc ttttgtttct ctaatactcg
     6481 gatcagaacg ctgatttcac attctctttt tcttacatct tatctggtgc atgaagtcct
     6541 agcaaacgaa ggtcttcttt caataataca gtcactgcat aaactagagc taagcgtgct
     6601 tctttttgtt catcatcagc taaaatcttc gtatgagcat agtatttgtt gaatgcttgt
     6661 gctaatttga ttgcatgttt cgcaatcact gacggttcgt atttttcccc agcagacaag
     6721 accgtttcag ggtatttttg aactaattta accacttccc agctggtatc gtcattcaat
     6781 gcatagtctg ctgtttctga agggacaaat cctgcttttt ccaacaggct gactgcacga
     6841 gcatgtgtat attgcacata aggtccagtt tctccttcaa atcgaacaac ttcttccagg
     6901 ttaaagtcaa atgtattcag tcgatcgttt ttcaaatcgt ggaaaatgac tgccccaacc
     6961 ccaacttgtt tagctacagc atctttgttt tccaaatcag ggtttttctc gctgatttgt
     7021 tctttagcag attggattgc ttcatttaat acttcttcta ataagacgat ctttccttta
     7081 cgagttgata attttttacc accttgcgtg atcaaaccaa atggaatatg gtgcatgtcg
     7141 tcagaccagt caaagcccat ttccttcaag acagctttca actgtttaaa atgatagctt
     7201 tgttcattcc ctactacata tagagattgt ttgaagtcgt aagtacgttt acggtacaat
     7261 gcagcagcta agtcacgtgt aatgtatagt gtcgcaccgt ctgacttctt aatcaacgct
     7321 ggattcaggt cataagcaga taggtcaacg atctctgcac ctttatcctc gttcagcaaa
     7381 tgtttttctt ctaaaagttt gacgatttca tccatcttgt cattgtagaa agcttcaccg
     7441 ttcaacgaat cgaaacgtac ttccagcaga tcatagattt tattgaattc tttcatcgat
     7501 tcatcacgga accattgcca taattgaata gcctctttat cgccttcttc cagacgtttg
     7561 aaccaagcac gagcttcttc atttaattct ggttctgttt cagctacttc atggaattgg
     7621 acgtataaac gaagcaattc attgattggt tctgctttaa cagcttcttc tgtaccccat
     7681 tttttgtaag cgacgatcag ttttccaaac tgtgttcccc agtcacctaa atggttgatg
     7741 cggattggct gataaccgat tttttccata atgaaaccga tcgaattacc gataactgtc
     7801 gaacgcaaat gtcccattga gattggtttg gcaatattag gagaagacat gtcgattggt
     7861 actgttcctt gattcccgat gttgctatcc ccataatgtt ctttttcttt cactactgtt
     7921 tgcaaaactt ttttgctgat aagttcttta ttcatgaaaa agttcaagta aggtccgaca
     7981 acttcgattt tttcaaagtt ggcagaatcg attttttctg ctaaatctgc agcgatttgc
     8041 tgtggcgctt ttcggtaaac ttttgctaat gaaaaggctg gaaatgcaac atctccgtgt
     8101 tcagctgatt ttggattttc tagtaattgc tcgacttgtt ccagtgttaa atcatctttg
     8161 acagcgtcat agacagcttt tgcgacaaga tctttattat tcatctttat tcctcctaaa
     8221 gtgttccctt gattgttaaa caaaaaaaat ctctagcgac ggcatactta gtatgccatc
     8281 actagagacg agatttcccg cggtaccact ccaattgtcc taaaaaagga ccagctccat
     8341 ctgatatcgg tagacgaccg tctgtttaaa acagaattct ccaagtgcgc ttcgttgtat
     8401 cttcttcatt cggcttccac cacttccgaa ttcgctagcc aagaatgata caagtactct
     8461 cttgttcaac aaatcttagt cttattaaac tttcttgaat tatatcagaa aaaaaaacga
     8521 aaggctagtc gtttcataaa aaaacaatcc agatggccta aaggagaaga aataccacct
     8581 ggatagctat aaatcatttc gtaaatacga aagacttaac aaattaatca gctacgataa
     8641 tcgttccttc ttcagaagct aaaagattct cgatattttc taaagaagtg atgattgcct
     8701 tagcgtttgg ttttgcttca acaaatgcaa tagctgcttc tactttcgga agcatgcttc
     8761 ctggagcgaa ttgcttttca tcaatgtatt gtttcatttc tgaaacagta acagtttcta
     8821 atttcttttg atctggtttt tggtaattga catacacatt gtctactcct gtcaatacga
     8881 tcagcaaatc cgcatcgatg atttcggcta atttttctga agcaaaatct ttatcgatta
     8941 cggcttctcg tccttctaat ccagtagctg tttctacaac aggaatccca ccgccaccaa
     9001 cagagactgt gataactcct tgatcgacca gcgtttcgat gacacgtgct tctttaatcg
     9061 agatgggttt aggggaagcg actacttttc tccatccacg tccagcatct tctttgaatg
     9121 tcacagtgga gtcagcattc atttgttctt tggcttcttc ttccgtgtag aatggaccga
     9181 ctggtttact tggatttttg aatgaaggat cattttcatc cacaataact tgagtgacta
     9241 aagaaaccac atctttatcg atcccttttt ccttcagtac ttcgcccatg gcgttttgta
     9301 accagtaacc gatagatcct tctgtcattg caacacatgt atctaaaggc attgccggtg
     9361 ttttctcaga atcagcagct tgctgctgaa tcaataggtt accgacttgc ggaccatttc
     9421 cgtgggagat gatcaattca tctccttgtt cgataaattt cactaaatac tttgctgttt
     9481 ccattaacgc ttcttgttgg gcttttgcac ttgcatccgt agacaagatg gcattgcccc
     9541 ctaaagcgac aactactttt cgtttggcca tttcattcgt cctttcttca gttctaccga
     9601 attttctaga taacaaaacg agccagcgtt ttgtgatttt ccctcaatgc tgactcgttt
     9661 tttcgtgaga tgaatgtggt tatgcttaaa cgcgagggat aaacaagtta cctaatgttg
     9721 ctgccatgat cgctttgatt gagtgcatac gattttctgc ttggtcaaat tgacgagcat
     9781 atttgctgcg gaagacttca tctgttactt ccatttcagt gatgccaaag cgttctttca
     9841 tttgttcacc gtaaacagtg tttgtatcat ggaaagctgg caagcagtgc aagaagatca
     9901 aacgatctgt gttgtgtgtt ttttctacca tttccatatt gatttggtaa ggtttcaaca
     9961 atttgatacg ttcttcgaat ttatcttctt cacccattga tacccataca tcagaataaa
    10021 ggacgtctgc tccgtctaca cctttatcaa catcgtcggt aatcatcaat tgtgcaccgg
    10081 atttttcagc aaagccttct gccattttga cgatttcttc ttcaggttgt aattcttttg
    10141 gtgcaacgat acgcatattc gctcctaaaa ttgcacctgt gactaataaa gagttagcca
    10201 tattgtttcg accatctccg cagtaagcaa cagtgatacc ttctactgtt ccaaagtttt
    10261 cttggatagt taaaaagtca gcgatcattt gtgttggatg ccattcatca gtcaagccat
    10321 tccaaactgg aacaccagag aattctgcta gttcctctac cattttttga ctgaatccac
    10381 ggaattcgat tccgtcaaac atacgtccta gtactttagc tgtatcttct gtggattctt
    10441 ttttacctaa ttggatatca tttgcaccta gatattcagg atgtgcacct agatcgatcg
    10501 ctgcagtagt aaatgcagaa cgagtacgtg tagatgtttt ttcaaataaa agcgcaatat
    10561 tttttccttc tagatagtga tgtgggatac cacgtttttt caagtctttc aagtgttctg
    10621 aaaaatcgat caaatattgt aattcttctt ttgtaaagtc tttttctgct aataagcttc
    10681 ttccttggaa tactgattct ttcatattaa acattctcct ttagattgtt tttatttaag
    10741 attaaagagg aaatcccgac ggcagctgac agtaagactg ccgtcaggaa acaaattact
    10801 tcaagtcttc acggacaagt ggttggctca tgcagcgtgg accaccacga cctcgtgaca
    10861 attcacttga attgatttct aacactttga tgccatagct acgaagcaat tcgttcgata
    10921 cataatttcg gttataagtg actacaacac ctggagcgat tgccaatgtg tttgatccat
    10981 cattccattg ttctcgaggt gcaacgatct catctccatt accagttggg atcagtacaa
    11041 gatcatctaa tccaagagca gctttcatcg tttcgtgtaa gttatctgaa tgagtaatct
    11101 tgatatcatc accatctggt tcgattgtaa agacatccat cttaccgtct ttactttgaa
    11161 ttgctggatg gatagtgaat ttatcgtgat ctaccattgt aaatacggta tccaaatgca
    11221 tcattgcacg gttgttcgga attttgattg ccaacacttt ttcaaatcct gaattttttg
    11281 cgaataggtg gcgtgctaat ttttctaaag ctttcgcatt agttcgttga gaaatcccaa
    11341 cagctactac tttatcgctt aagatcaatt cgtctccgcc ttcgatatga tctggatttt
    11401 cacgatccaa ccatacttcg attcctttat ttgcaaatct tggatgatgt ttcaaaatat
    11461 attctgtaaa catcgattca cgacgacgtg cttcaaaagt catcttattg actgtcatcc
    11521 catttcccat tgatgcggaa gggtcgcgtg taaagtacaa gtttggcatt gggtccatgt
    11581 aaaatggata gtcatcgtct gctgacagat catatagact gctagaacgt acttcgatat
    11641 cttttgtacg aaccccagcc atgattttat ctaccatttc ttgcgtttcc attgatagaa
    11701 ggaactcatg aagaccctct cttacagcat tcgatgcaat atgagattca tccaacattt
    11761 tattcaagaa ttgttctttg acattgcctg cgtcaatcgc ttctgccgct aatttttcca
    11821 agtaaagagt ctcgacgcct tcattttgca atgtcttcgc aaagttgtca tgttcttctt
    11881 gagcaatcgg aagatatgga atatcatcga acaacagacg atccataata tctggtgtca
    11941 aattttccac ttcttgtcca ggccgtttca gtaaaactgt ctttaatttc cctatttcag
    12001 agaaaacgtg aataggttta tccatgttgt gttgcctcct tctttttgat tacatgtata
    12061 ggatatcctc cttttgtaat cactttcata attttgtctc attcaaaatg agacattcct
    12121 cacattaata ttcgataatt aaataattaa acgtttttct atttttaagc gtaatttatt
    12181 cattttttat tctgtataca ctttcaaaaa aatatttatt cattg
//
LOCUS       DAFLWZ010000076        12200 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000076 DAFLWZ010000000
VERSION     DAFLWZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.078"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(162..326)
                     /locus_tag="L1V38_002292"
     CDS             complement(162..326)
                     /locus_tag="L1V38_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316826.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            621..1949
                     /locus_tag="L1V38_002293"
     CDS             621..1949
                     /locus_tag="L1V38_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBN1316827.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2151..2984
                     /locus_tag="L1V38_002294"
     CDS             2151..2984
                     /locus_tag="L1V38_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBN1316828.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3000..3737
                     /locus_tag="L1V38_002295"
     CDS             3000..3737
                     /locus_tag="L1V38_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBN1316829.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3892..4860)
                     /locus_tag="L1V38_002296"
     CDS             complement(3892..4860)
                     /locus_tag="L1V38_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBN1316830.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5092..5925
                     /locus_tag="L1V38_002297"
     CDS             5092..5925
                     /locus_tag="L1V38_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBN1316831.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5959..6798
                     /locus_tag="L1V38_002298"
     CDS             5959..6798
                     /locus_tag="L1V38_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1316832.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6824..7384
                     /locus_tag="L1V38_002299"
     CDS             6824..7384
                     /locus_tag="L1V38_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1316833.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7583..9304
                     /locus_tag="L1V38_002300"
     CDS             7583..9304
                     /locus_tag="L1V38_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBN1316834.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9469..10611
                     /locus_tag="L1V38_002301"
     CDS             9469..10611
                     /locus_tag="L1V38_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1316835.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10627..11838
                     /gene="thiI"
                     /locus_tag="L1V38_002302"
     CDS             10627..11838
                     /gene="thiI"
                     /locus_tag="L1V38_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBN1316836.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4155 a         2048 c         2535 g         3462 t
ORIGIN      
        1 taggttcgag tcctactgcc ggagtaaata aagcttatgc aaagaaaaag aaatccaatc
       61 acttgggttt ctttttcttt tattattatg atgaatcaag ctttctgttt ttgtcacgta
      121 tgttgtaatc tttacgaaag agtagagttg gctactcata atcaaccata cttcccatca
      181 tcgctaaata cgaaataaat cagcattcct acaccaatca aagcacaagc tgcaccaaga
      241 aaagggatga cattcccaaa gttatctgta ttcataagta tgccaccacc cacaaacaaa
      301 aagccgccag caatcaggtt tttcatttta ttcatctcct ttcttacgtt atagtatttc
      361 cttctttcaa tgagtatttt gaaagctatc ttattgtatg atgttcttct aggcctcttc
      421 tttattatac aggccatttt cgttatctca tagaaatatt cctttttatc tgaaaactat
      481 tgtataccgt atgacatttt tcttcatgaa gttgtaagta tattctcatt caaatgaaaa
      541 tttcatcata gaagagattg tatttctaaa ttcttaagag taaaatacga agtataactt
      601 ggatttggaa ggatgattgg atgaaagcta ttacgcctga tatgacaaca aaatttaaca
      661 aacagtttca agcaaatatc aaacagcagg cattgcagcg ggcagttgtg aagaacggaa
      721 ttactgcttc tgctgaaaat gtttcagcac atgtggagaa tacaccggta ttttctatag
      781 atttggctac ggggaaagtg gctaatcaaa tgcaatcggg gcgttgctgg atgtttgctg
      841 cactgaacac attccgtcat aagatgctga atcaattcca tttaaaagag tttgaattat
      901 cacaaaatta cacttttttc tgggataaat atgaaaaggc aaattatttc tatgaaaaca
      961 tcattgcaac aggaaaagag gcaatcgata gccggaaagt agctttctta ctcgctactc
     1021 ctcaacaaga tggcggccaa tgggatatga tcgtttcatt attccaaaaa tatggcgttg
     1081 tgcctaaatc ggtgatgccg gaaagtgcga atagttcaaa ttctcgagat ttgaataact
     1141 acttgaacaa attactgcgt aaagatgcag tagtgttacg gaaaatggtt gctcaaggag
     1201 aaacattaga cgctattgaa gaaaagaaag aagaaatgct agaaagcatt tataacttct
     1261 tagctatctc attaggaaca cctccaaaag aattcgattt tgagtaccgc gatgaagaaa
     1321 agaactatca tcttgaccga ggactgacac cacaaatttt ttatgataaa tacatcggtg
     1381 taaaattaga tgattatgtt agcgtgatca atgcaccaac aaaagacaaa ccattcaatc
     1441 gttcttatac agtagagatg ctaggaaatg tcgttggcgg gaaagaagtc aaatatctga
     1501 atgttgatat ggaaactttc aaaaaattag cgattgctca gcttgaagaa ggagaatctg
     1561 tttggtttgg ttgtgatgta ggtcaatctt ctactagaac tagtggcatc atggccttag
     1621 atgcttattc aatggatgat ctatttgata cggattttac aatgactaaa gctgaacgtt
     1681 tagattttgg agaaagtctg atgacccatg cgatggtatt gaccggtgtt gacttagtag
     1741 acgggcaatc aacaaaatgg aaagtcgaaa atagctgggg cgaaaaagtt ggaaagaatg
     1801 gcttctttgt tatgagtgat gcctggatgg acgaatatac gtaccaaatc gttgtaagaa
     1861 aagatttatt gacgaaagag caattaaatg cgttcaatga agaaccaatt gttctatctc
     1921 cgtgggatcc aatgggtgct ttagcataga cgagtatttc aatgaagagt atgtagtaaa
     1981 gataaaaaga gctggcttaa gccagctctt tttatcttta aagtccattc cctgtttttt
     2041 atggtccctg tgctataatt ctaaataaag gataaggatt ggaaataatc cttttatcat
     2101 taaaaatatg atgacgaagt agaataaaat tgggagtagg ggggaaagtc atggatatcc
     2161 aaactgtttt atctgatctg aaattaaatg gtaaagtgat tccagttgtt ggtggcgatg
     2221 ttaatcagac ctatcgtata aaaaccgaac atcgtgctta ttttttaaaa atccatccga
     2281 atgtaaaaaa aggatttttt gaagcagaag tagacggatt aaaagaactg tcagcattcg
     2341 tacgtgtacc ggatacgtat atgctaggtg aaacaagtga aggcgcttat ttgttaatgg
     2401 aatggatcga gccgggaaaa ggggatcaac gagatcttgc tgcagcttta gctaatctcc
     2461 atcagcaaac agcgccacaa tttggttttc gtaaagataa ctatttgggt acacttgttc
     2521 agaaaaattc ttttgaagaa gattggtgga cttttttctt taaagatcgg cttgaatccc
     2581 agatttcttt ggcagaagaa acgaatcgat ggaatgtaca gcgtcaagaa aagtatctgc
     2641 gatttaaaga acgtgtattg aaatcggttg aaccaaaaaa gatcactcca cgcctcttgc
     2701 acggagacct gtggagtggt aatgtgttct ttgaccagca agggcatcca gtttttgtcg
     2761 acccagctgt ttcttatggg aatcgggaac aagatattgc aatgagccag ttattcggtg
     2821 gtttccgacc ggaattttta gatgcttatc aaactatatt tccattagaa aagggatgga
     2881 aagaccgact gccgatttac cagttatatt atcttttggc acatttgaat atgtttggag
     2941 aaagttacgg ttcccaagta gatcaattac tagaaaattt ttaagaggag ggcgtgtttt
     3001 tggcaaaaaa atataccaaa aagcatgaag tttcatatta tgagtgtgac atcaaccaaa
     3061 cgatgacatt tccttcgatg ttaggagtag ttatcaaaac gtctgaagat caaagcgacc
     3121 agttgggaag aggcagtgaa ttcgtcaata gctttggact tacttgggtc atcacgaatt
     3181 attccatgga gattaatcgt ctccctagag tcggtgaagt aatctcagta acgactcaag
     3241 ccatggagta caataagttt ttctgttatc ggaacttctg gatccatgat gaagatggga
     3301 aagaattagt caaaatagaa tctgttttcg tattgatgga ttttgtgaat cgaaaaatga
     3361 gcagtgttaa tgaagagatc attgctcctt ttgagagtga gaagatcaag aaaatcaagc
     3421 gtcaggaaaa aattgaaaag attgattcgg gcttcatgtt gccatatcgt gttcgttttt
     3481 atgatatcga tagtaatcag catgttaata atgcgatgta ttttaattgg atcattgacg
     3541 tattaggata tgactttttg actacgcatg ttccagaaaa agtaattatt cgatttgata
     3601 aagaagtaga gtacgggaat gagatcgaaa gccattttga acaaatccct atcgaaaatg
     3661 gtgtcaaaac aaaacatgaa atccgaatgc aagaacagct gtattgtgaa gcaaatatta
     3721 tatggaaaaa taaataaaaa agaggttgtg acagaagggg gcaacttcaa gaaataagaa
     3781 gaaatttacg aaaattgttt ctcaaatttt tgtaaatttt cgacttagtt ttcgaagaag
     3841 ctatttttgt cacagcctct ctttttaagt ttagctatta gataatgatg tttagttttg
     3901 gataaacgaa atcaattctt cacccgacaa accatagttt acagcaatca atagttttaa
     3961 acgtgctttt tgactattaa tactgttaca gaaaataatc cccatttttt ctagttcttt
     4021 tcccccgcct tcataatcat aaacaggctc tgcgattcca ttgaaacaac gagaaacaag
     4081 tactacaggg attttttgga caagaagctt ttccaaagca gctaaggctt gtggagggag
     4141 attccccgca cctaaagctt cgattaccaa accgtctact ttcgtatggg cgatggcttc
     4201 caataagtcc ccttgcatcc cagcatatgc tttaacgatc gggatagtcc catctacagc
     4261 ggaaatgtcc agtcgctttg tttctaaaag ttcctgcaag aataaaattc gattcttagt
     4321 tactaagccg atgggaccca atgtaggtgt tcggaaagta gcaacatttg tggtatgggt
     4381 ctttgtcacg tagcgtgcag aatggatctc atcgttcatg accaccaaaa cccccttatc
     4441 tagcgcttct tcacaacttg cgacacgaat cgcactttca aaattataaa ggccgtcact
     4501 tccaagttca ttacttgaac gcattgcccc agtcaaaaca attggtaatt tgttgccaat
     4561 cgttgtatca agaaaaaaag cagtttcttc taatgtatct gtaccgtgtg tgatcaccac
     4621 tccggatata cctgatgcat aagcggacaa gatacgttct tttaatacca acatgtgaga
     4681 aggcatgatg tgtggtgagg gaagattgaa gatatcttca actaataatt ctacatgctt
     4741 ggggattgtg atttctgcat ctaataatgg gtttgccaca tcaggactaa caccgcccgt
     4801 gagcatgttt tctttcatgg cgatcgttcc gccggtgtgt agtacaagta tttttttcat
     4861 tttacagact tccttacgaa taattttgca tagccgttaa atcttattgt atactatata
     4921 aaagagtttt gctatcagtg aagaataacg aatagcctaa cttatcataa aaaagctgac
     4981 cttattaaaa tggaaaagac tcaaccttga cctcctaata caatggagta tctggttgag
     5041 tttcttttac aagaaagcag ccaaggaaat caatcacgaa ggtggccgga aatgatcaga
     5101 atcggattaa catcgtttaa agaacatgac aaattaactg gtaaaaagaa taacactctt
     5161 tatgaatatg cagggtttct acccttagtg gaattagata ctgcctatta tggaattccc
     5221 cgaaagtcct cagttgagaa ttggataagt gaagtacctg aatcatttcg ctttgtagtc
     5281 aaagtctatc aaggaatcag cggtcaagga gactggaagc cttattatca gaccgaagaa
     5341 gagatgattg cgcatttttt agatgttatg tcgccaatgg tagatgctgg aaagatgttt
     5401 tgctttttag tccaattccc ctcatcattc aaatgtacga aagaaaatgt ccagtacttg
     5461 cgcaaactta gaaagtggtt tgagggttat cctgtttcta tagaattgcg ggattattct
     5521 tggtacagcg atgaatttct tgaacgtaca agaaacttta tgtctagagc cgctttttct
     5581 ttagccatca tcgatgagcc acagttgctg aatacaacga ttccttttga tccatttgtc
     5641 accaatccga actttgctct ttttcgattc catggtagga atgcgcaagg atggcaagca
     5701 aatgataaag agtggcgtaa aaaaagaacg ttatatcgtt attcagaaaa agaactgcaa
     5761 gaactagcac atgaagtcaa agtagttgat tctaagacaa aagaggtagg tgtgattttt
     5821 aataataatt ctggtggtga tgcggctgaa aatgcattag cactgcaaaa aatattaaat
     5881 atcaagccag atggactcaa tccaacccaa atggatctgt tttaagggct tattttattc
     5941 aagaaagggg cgaagtctat gatcaaagct attttttttg atattgacgg aacattggtc
     6001 accaatcgtt caaaagcgtt ggaatcaaca aaacaagcaa ttgaatatgc tcggaaaaac
     6061 ggcattttat gcggtgtagc aacggggcgc agcccagtaa agatcaaaga aatcattgat
     6121 gaattggaat tagatatgta tgtcgtgtat aatggtcaac tggtttttac tgcagatcgc
     6181 acgattatcg accacccttt tgaacaaaaa gtattggaac atattgttga atttgcagat
     6241 gagaaccatc gacaaatcgt ttttggtgcg agaaatcggt tagatggatc aacgacgatg
     6301 ctattaggac aatcgatttt tatcaagcga ctagtcagct ttttaccgcg taaattcccg
     6361 gtacgtctga tgaaaaaaat cctccaggtt tttagccctc accgacaaaa ggatcgttat
     6421 gaaacgttag agatattaaa agaaccaatt tatcaatgta tattgctcag tccggagtca
     6481 gaacagaaaa agttagaaca tcgctttccc gagtgtacgt ttcagcgttc aaatacgtat
     6541 actgtagata tcatcccaaa aggtggttca aaattactag gcatccaagc tttcgcaaat
     6601 gctgtcgaaa ttgaaatgga agaaattatg gcattcggcg atcattacaa tgatatcgag
     6661 atgctgaaag gtgtaggaat tggagtggcc atggggaatg ctcagatcga agtaaaacat
     6721 gctgcagact ttgtgactca atcaaatgaa gaagatggga tatacgaagg actgaaacac
     6781 ttcggtctga tttattagtc aatgaaagaa ggaaaaaatc agtatggaag cagagacacc
     6841 ttttcaaaaa gtagaaacat tccacaaaac ttttgatcca agaagaccag agatacccac
     6901 ggcttttaca gaaaatgaag ctcatacacg tgctgcgttc aaaatagaag aacttgttga
     6961 atttgttgca gctacttcac ctaataaaga acaactgcat gaagctgtta tgctgctgca
     7021 cgaagcatta gataaagcag aagaaaaaat acttggtaaa acacagtggg gaagtgatcc
     7081 gctggttgaa caagtagatg cactgacaga tatcctttac tttacttatg gttctttttc
     7141 attactagga atagtgcctg atcgaatatt cgaaatcgtc catcaggcaa atatggggaa
     7201 attatttcca gatggaaaac ctcattatga ccctgtaaca aataaagtgt tgaaacctga
     7261 aaactggcag atggaatatg ctccagaacc taaaatcgcg gcagaaatcc aacgtcagat
     7321 tcaagaagcg attgctaaga agaaatccgc tgatataggc atgtgcacaa atgaaaaaga
     7381 gtgatcagag tttcactatt tttgttatct ttatacgatg gaaaaacaaa agattttcgt
     7441 ttaagttagt gaatgcatga aaatagtatg ctataatcta gaatagatgt cttttgcacg
     7501 agagacgtat tatttggatt tatgccaagc agaacgccat ctgttgcata aaagatgcat
     7561 actgaaaacg gaggaaccat aaatgggaaa taatgttatc atcggaatcg tcattgcaat
     7621 cattatagtc gccattgtcg tctttttggt tagttacttg atgaagaaaa aaaaccaaga
     7681 tcgattggat gccttagaaa aacgcaagga agaattattt gacttgccag tgattgaaga
     7741 agtcgatgat gttaaaaaaa tgcatctggt tgggcaaagc caaaatacct ttcgtgaatg
     7801 gagtcaaaaa tggaatgaca tatctacttc ctcgttcgct gaactagaaa gtcaaatttt
     7861 cgaagtggaa aacctcaatg aaagttttcg gttcttaaaa ggaaaaaaag cagttgttga
     7921 agcagaagct acaatggacc aaatggagaa acaagtgacg gaaatccgtg aaggtctaaa
     7981 ggaattgcgg gaaacggaag aacgcaactc actagctgtt cagcaggcac ttgacgtcta
     8041 tgaagaactg aaagaaaaag tcagagaaga cgagcatgaa tacggaccag ctctttttga
     8101 attgcaaaaa cagatcaaag tgatcgaaaa agaatttacg cagtttgtga ctttaaacac
     8161 ttctggagac cctgttgaag cccgcgaggt tttggataaa gcagaaaaac atacgtatga
     8221 agtggaagct ctgatgaaaa aaattccacc gctgtatgag gagctccata ccactttccc
     8281 tgaacaactt gaagaaatca gtgatactta cgagaaattg atggaagaac aatatgtatt
     8341 cccagaagaa gatcttgctg aagatatcgc aaaagtaagt cgaagaattg aaaattcatt
     8401 agccaatctt gaaaaaacag aagttgaaac ggtcgaattt gaaaaccgtg aaacagctga
     8461 tttgattgat tcgttatatg atatcttaga acgggaaatg gaagctcaga gatatgtaaa
     8521 aactaaccaa tcaacgattg cagagtatat caaacataca acaaagaata accgtcaatt
     8581 attgattgag ctggatcaca catctcaaag ctatacattg aaccacaatg aaattggccg
     8641 tgtacgaggt ttccaaaccg aagtggaaga aatggaacgt caaaatgaac agatgattcc
     8701 acagatccgt caacacgaaa ttccttattc agaagtgcgc acgttctata aaacagtctt
     8761 caaagtctta gaagatatcg aaaagcaaca agtagagatc gacgactcat tacatgaatt
     8821 gagaaaaggc gaaaaagaag cgcaagaaaa gatcgataca ttcgaattca aattgcgcag
     8881 tttgaaacgt tttgtagaaa aacaacgttt gcctggcttg ccgaatgatt acctagaatt
     8941 cttttttgtt gctactgacc gtattgaaga actaagtgtt gtcttgaata aaattcgagt
     9001 aaacatggaa gaggtcaatc gtttagttgc tctatgtgaa gaagatctag aattattaga
     9061 taagaagaca catgatttag tagatgcagc agcattaacg gagcaaatgc tccaatatgc
     9121 aaatcgttat cgtcatacac acgaagaagt gagagaagca attgataaaa gctactattt
     9181 attcaataaa gaatatcact atcaagaagc attagacgaa atcggtacag cattagagcg
     9241 agtagaacct ggtgctttca aacgcatcga agatttttat tttaatcatc cagacttagt
     9301 ataaagcaaa aaagttagta aaccagcaag agcaagacgg attattgtct tgttcttgtc
     9361 tttttttgta tatttgaaaa ttgaaacaag tgaaaatttc acctgctctt gaaagcacct
     9421 tggacaaccg ttataataga aaagaatttc aaaaaagagg ggtttcttat gatatatttt
     9481 gataacagtg caacaacccc aatctttccg caaagcttag atgcatatgt aaaaaccagt
     9541 cagcggatta ttgggaatcc atcaagcttg catgatttag gcaatcaagc taaccggttg
     9601 ttgcagcaag caagaaagca gatcgctgat ttgatccatg tagaaccaga agaaatctat
     9661 tttacttcag gcggaacaga aggagataac tgggtattaa aaggaacgat gatcgaaaaa
     9721 agagaatatg ggaatcatat gatcatttca ggagtcgaac atccggccgt cagcgagaca
     9781 gcagaacaat taaaagaatt aggaatcgaa gtaagtatcg ccccagtgga taaacgcgga
     9841 tttgtacgtg tcgacgaatt gaaagaatta ataagaaaag agacagtatt agtctctgtt
     9901 atggctgtga ataatgaagt aggatcgatt cagcccatcc aggaaatcag tgatcttttg
     9961 gatgattttc ctaaaattca tttccatgta gatgctgttc aggcgattgg aaaagtacca
    10021 ttctcgcaat ggttgacaga aagagttgat tttgcaacat tttcagctca taaattccat
    10081 ggcccacggg gaactggttt catttattgg aaaaagggtc gtcgtttagc accattactg
    10141 acaggtggag ggcaagaaag aaatcagcga agtgggacag aaaatgttcc aggtattgtg
    10201 gctatggtta aagctttacg tttatcatta gagataaagg aacaaaaacc tgagcagaca
    10261 caacgcttaa aagtagctct aatcaatgcg ttgaagacgt atgagaaagt gacgattttt
    10321 tcagaaggaa ctgactatgc accgcatatt ttatgttttg ctctaaaagg aattcgcggc
    10381 gaagttctcg tccatgcctt agaagaaaaa caaatatttg tttctactac tagtgcctgc
    10441 tcctcacgta aacatatggc aagcagtaca ttgcacgcaa tgcatgtacc aaatgatctg
    10501 gctacatctg ctgttcgaat cagcttagat gaaaacaatt cgcttgcaga agtcgagcaa
    10561 tttatgatta ttttcaagca gctttataag aaattttctg caatcaatta aaagaggagt
    10621 gttcttgtga aatacagtga aattatggtc cgttatgggg aactttcgac aaaaggaaag
    10681 aatcgaaaaa gctttatcat gcaactagca caaaatgtca gacaagcttt gaaagacttt
    10741 ccagaaatca aaatccatgc tgatcgggac cggatgcatc ttttattgaa tggcgcagac
    10801 gggcagctag ttattccaaa actagcaaaa atatttggga tccaaaattt ctctccaagt
    10861 attcgtgtag aaaaagatgt cgaagttttg aaacaagctg ttcaagacat catgaaagaa
    10921 atttatactg ggaaagaaac atttaaaatt atcgctaaaa gaagcgatca ccaatttgaa
    10981 ttgacaagta atgaattgaa tcaaacatta ggtaatgctg tttttgatat tttcccgcat
    11041 atccaagttc aaatgcgtca accagatatt ccattacgtg tagagattcg gcgtgatggc
    11101 gcttatctat cgtatgaaac gatcaaggga gctggaggat tgcccgtagg aacaagcgga
    11161 aaaggaatgc ttatgctttc tggggggatt gattctcctg tagcagggta ctttgccatg
    11221 aagcggggag tggaaattga agctgttcat tttgctagtc cgccgtatac aagtgaacaa
    11281 gcactgcaaa aagcaaaaga tctaacagcc aaactagcac cttatgtggg aacgatccat
    11341 tttatcgaag tgccatttac cgagattcaa gaagaaatca aaaagtcagt gccacaagga
    11401 tattggatga caattactcg tcgaatgatg ttgcgtttga ccgatgaaat tcgccgtatt
    11461 cgtcatggtt tagtcatttt gaatggtgaa tcattaggtc aagtggcttc acaaactttg
    11521 caaagtatgg tggctatcaa tgaagtaacg aatacgccaa tcattcggcc tgtagcgaca
    11581 atggataaac ttgaaatcat tgaagtagca gaacagatcg atacatttaa tctttctatc
    11641 cagccttttg aagattgctg tacgattttt gctcctccac agccaaaaac acgccctcaa
    11701 ctggaaaagg tccatcaata tgaagagcgt ttagcaatag atgaaatgat ccaacgagca
    11761 ctagctggct tgaagatgga agagatacaa gcagaatcgt ctaatgaaaa aactgaagaa
    11821 ttttcagaat tgctataaga ggttatgaaa atagtgtttt gaccagagta ttagagaaac
    11881 aaaacgaaaa aatagctcca tgtattttac cgtttttgaa ctaatgtcga agattagctg
    11941 attgaatacc atttatcaag aagttatgga aaagccggtt cttttttact aactgaaaaa
    12001 taaaatttta tttagagatc aagctacagt tgataaatga tataaaaaag agaatttccc
    12061 atgaaatagc gaggttgtga cagaagtggg cagcttcaag aaataagaag gaatttacga
    12121 aaattgcttt tcaaattttt gtgaaatttc ggcttatttt tcgaagaagt tacttctgga
    12181 acaccgtgta tcagaggttg
//
LOCUS       DAFLWZ010000077        11927 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000077 DAFLWZ010000000
VERSION     DAFLWZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.079"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            560..1531
                     /locus_tag="L1V38_002303"
     CDS             560..1531
                     /locus_tag="L1V38_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBN1316837.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1609..1845)
                     /locus_tag="L1V38_002304"
     CDS             complement(1609..1845)
                     /locus_tag="L1V38_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1316838.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1814..1945)
                     /locus_tag="L1V38_002305"
     CDS             complement(1814..1945)
                     /locus_tag="L1V38_002305"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1316839.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2021..2404)
                     /locus_tag="L1V38_002306"
     CDS             complement(2021..2404)
                     /locus_tag="L1V38_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1316840.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2437..3222)
                     /locus_tag="L1V38_002307"
     CDS             complement(2437..3222)
                     /locus_tag="L1V38_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBN1316841.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQRPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3400..4500
                     /locus_tag="L1V38_002308"
     CDS             3400..4500
                     /locus_tag="L1V38_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1316842.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4490..5314
                     /locus_tag="L1V38_002309"
     CDS             4490..5314
                     /locus_tag="L1V38_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBN1316843.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5311..6126
                     /locus_tag="L1V38_002310"
     CDS             5311..6126
                     /locus_tag="L1V38_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1316844.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6123..6953
                     /locus_tag="L1V38_002311"
     CDS             6123..6953
                     /locus_tag="L1V38_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316845.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            6960..7991
                     /locus_tag="L1V38_002312"
     CDS             6960..7991
                     /locus_tag="L1V38_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316846.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8098..9371)
                     /locus_tag="L1V38_002313"
                     /pseudo
     CDS             complement(8098..9371)
                     /locus_tag="L1V38_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9648..9857
                     /locus_tag="L1V38_002314"
     CDS             9648..9857
                     /locus_tag="L1V38_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316847.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            9907..10623
                     /locus_tag="L1V38_002315"
     CDS             9907..10623
                     /locus_tag="L1V38_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1316848.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10525..11045)
                     /locus_tag="L1V38_002316"
                     /pseudo
     CDS             complement(10525..11045)
                     /locus_tag="L1V38_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11333..>11927
                     /locus_tag="L1V38_002317"
     CDS             11333..>11927
                     /locus_tag="L1V38_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1316849.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT         3434 a         2201 c         2721 g         3571 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagctaat tttatgatta aatggtaagt ttttccttgt gtgttttagt ttaaactagt
      541 gtgtaattca aaaatctata tggaaggaac agtattaaga atagaacagg gttctctaca
      601 tgatggtgct ggtttacgga ccgttgttta tttaaagggc tgcccattac gctgtgcctg
      661 gtgttcgatt cccgaatcac aaagcaagca gattgaaaaa ggatttggcc agaccatgac
      721 cgctgaagag gtaatggatg agattgagaa ggatgctgtt ttttactttc actcggatgg
      781 cggagtgacc attagcggag gcgaggcact ggttcaggcg gattttgcta aagaaatttt
      841 gcaaaaatcg aaatacattg gaatcaatac cgtactggaa accagctttt gtggtgctta
      901 taatgaaatc caaaaggtag ctccctatgt ggatacattg tttgtggatg taaaaatgtt
      961 taccagcaag ctccacaaac aatggaccgg cttagataac caacaaattt tgaagaatat
     1021 tcgtcgcttt ttaattgagt atcctaactg cgaagtgcga attcgagttc ctgtggttcc
     1081 aggtatcaat atgaacctga ccgagctgct gacgattgct tgttttgtgg cagatcttga
     1141 tcggttcgta ccgttagaat tactaccgta ccactgctat ggtatgcacg gttaccaagc
     1201 attgggactg gagtatccgt tggcagacac gccagcgcct tcacctaaag aaatgtttgc
     1261 attggcagat caactggctc gcacggttcc tcatttgctg gtcacagctt taaccaaaac
     1321 atttatttat ttattgaatc caagctttat cttatggata aatgaaagac actcactagc
     1381 tgcagccagc tcaagaatag agcttttgct gaagtcagtg agtgtctttt tacgatgttt
     1441 tttcgaagtt aatttgtcga atgaacactg gctcaatcgg tacatcttca ctgtttgtcg
     1501 gctgagctgc gatcgctgct acgatttcta acccttggta tacctgtcca aaaacagtat
     1561 aacgaccatc cagctccggt agtcctccaa gctccaagta tgcttgcttt acattagcag
     1621 gtcagcctgc gcctttgtgt tttgcacaat aaaaaactgg ttgccgttgg tgtgggggcc
     1681 gtggtcccct aaggccaagg cgccattaaa atgataaagt ccgcgatgca cttcatcagc
     1741 gaaaaagccc tcatagctgg aaacagcttc atcaccagaa ccatccaaag cgccaccttg
     1801 aataacaaat tccttaatga cacgagccga aaggtgtgtt gtcataaacg ccttgctcag
     1861 ctagggagcg ccagttggct acagccaggg gagcttggtc aggaaataag cggagacgaa
     1921 tttcaccagc atcggtgacc agcacacaaa cttcttcctg ctgcggtttt tctaattgaa
     1981 agagaggaag gtttgcaact gaaacgcctt gatcctgcca tcaaatatcg aaaatccgcc
     2041 actcgacctt cgcctgatca ccaaggcgag ccattcccaa taaaacggta taggcggttt
     2101 catccgcttg aaaggtcaat tgcagctgtc ctcgtaaatc gttgtagtca tctggggcgg
     2161 ctacttgata aaaaagatga aactgcgcat gcaaatattc caaaggctga tctttaaagg
     2221 ctgcaaaata agcctgaact ttttcccgct gcaagctgtc agccaccaaa aaattttcca
     2281 gttgttgttt tggaacggct gctaacaagg atcggcaaac cgcctcaatt ttcaacgcat
     2341 cccaatgtcg cgcaattaaa taatggatgg gtgcctcttg attgtagtcc cacaggttgc
     2401 tcattttttt caccactttc ttctattata taggaatcac aaaatcggca gcggcgtcag
     2461 gcggcgttct tttccttgaa tgactagcaa cttttctacc tgacagtctg ccaacagctg
     2521 actcattttt ttaaagccca gctgataatc ttcggcaaca tgagcatccg agcctaaggt
     2581 aaagagcttt ccgccgacac tttgatacaa aggaacggca taacggtaaa ggtcttcgtt
     2641 gccgtatttc aagaagctct tggcatttaa ctccatcgcc aattctcgtt caacaacctt
     2701 tttgaaaatc gttagcagct gagcctcaaa atgctccgcg aattcttccg ctgtgaaggt
     2761 gaagcggcgt aatccataat caaagtgagt caaaatatct ccttctggaa aatccgtcaa
     2821 gacctgcaac atctgatcaa aatattcctt ggtagtttga atgggatctt tggttaaaac
     2881 cacatcgtcc atataatcaa agcggccatt ttgatgaata cttaccagct ttaaatcata
     2941 aggacgctga gcgaggtaat ccacgatccg ctcttcttgt cctggaacaa cgccaatctc
     3001 gatacctcgc agaaatttgg tggaataggt ttcttttaaa gagtccagtt tgtttatata
     3061 ggctggataa tccggaatgt catcttttcc ggtagatgga ttgtttaaat caaagtgatc
     3121 cgtagaaacg aaaaactccg gctgataggc taaatagttt tcaaattttt cctctgaatc
     3181 aaaggaaaaa tacgtgtgga gatgctgatc ataatactgc atagggagcc tccttttttc
     3241 tactatcata ccgcaaaagc tttagaaggt taacgggaat tcgtcgaaat ttacaaacca
     3301 tatacaacct ttacattgtt catgaaacct tttcaagaaa ctgattctct cattacaaag
     3361 ctttgttaga atggaattat cgaaagggga gaagaatgaa tgaaaatgaa tgaaaaaatt
     3421 cgtaacatga ctatcggttt attttgtgca gcaacagtaa gtatcctgct gacaggctgc
     3481 ggctcaggtg aagcaacgaa gcaatcggct gcggcagacg actctttaga tacgattata
     3541 gaaaaagcca aggaagaagg agagattgcc agcttgggaa tgccggatac ttgggcaaat
     3601 tgggtaggca cttggaacga ccttgaaaaa gaatacggct taagtcacgt ggatacggat
     3661 atgtccagtg cagaagaatt ggctaagttt gaatcagaag gaaaaaatgg aaccgccgat
     3721 attggtgatg tcggtatcag cttcggtccg ttggctgaaa gcaaagagtt aaccttacct
     3781 tataagacca actattggga ggaaattccg gattgggcaa aggatgatga tggggattgg
     3841 ttgttaagct atacgggaac catttccttt atcaccgata aagagaatgt gaagcaagca
     3901 ccgactagct ggaaggagct gcaagagggt gactatcaag ttagcgtggg ggatgtgacg
     3961 attgccaacc aagcacaatt tgctgtattg gctgcggcga ttgccaacgg aggtgacgaa
     4021 aaggatattc agccaggtct gaattactac aaaaaaatgg cagaaaaagg ccgtttgtcc
     4081 accgttgatg ccagcgtagc aaatcttgaa aaaggtgaaa tcgatgtggc agttgtttgg
     4141 gacttcaatg gactaaatta tcgtgaccaa attgactccg agcgttttga ggtaactgtg
     4201 ccaacagacg gctccatcat tagcgggtat acaaccttaa tcaataaaaa tgcccctcat
     4261 cccaatgcgg caaagctagc acgggaatat attttatctg atgaagggca aatcaatttg
     4321 gcaaagggct atgcgcgacc tattcgcaag gtagagctgc ctaaagaagt agctgaaaaa
     4381 ttactgccgg aggatgctta tgaagcggcg gtgccagttg aagacaatga agcttggaac
     4441 aagacctctg tagagcttcc agagctttgg caggcggagg tactgaccta tgcaaagtag
     4501 acttgacaaa ctgattgtag ttatactaga cggctgtcgc tacgacacag ccgtcgccca
     4561 gcttgggttc atgaatcatt tagttgagca ccagcaagca agcttattga aggtaaaaag
     4621 tgagctgccc agcaattcac gtccgttata cgaagtactg atgaccggcg ttccagccta
     4681 tgaaaatggc atctatagta attaccatgc tcagcgatcc aaagagtggt cgctgtttga
     4741 attagttaag gaagctggcg gaaaaacagg agccgccgct taccactggt acagcgagtt
     4801 gtacaatcaa gccccctata atcgtttggt tgatcgcatc cagcatcagg aggagcgact
     4861 gattcagcat ggcatctttt atagtgagga cacttaccct gattcgcatt tatttgcgga
     4921 tgcccattat ttagtgaatc agtatcagcc agactttttg gtcgtacatt cgatgaatat
     4981 tgatgatgtc ggtcacaaat ttaccgccga ttctcatgaa tatgcagcag cggttaatca
     5041 ggcggacaga ttattggcta tttaccttcc tgaatggctg caaaaaggtt atcaagtcgt
     5101 ggtgactgcg gatcacggga tggatgcgca cggactgcat ggcggcagct tggctgcaca
     5161 tcgtgaagtt cctttttatt tgatttcaaa taaacgccaa aagctgaagg aacaaactgt
     5221 accacagctg ctggcggctc cattgttttg ctggttatta ggaattgcac cgtcagagaa
     5281 aatgcaggac attcaagaat tgatgagggg atgaaagaga tgaaaaaacg cttggttctg
     5341 gttcctgcct cctttatctt ctgtgcattt ttactgctgc cgctgctttt tatggttctg
     5401 tgcagcttgc acagtgattt aactaaccag tggacattgg ccaattacag tgatattttc
     5461 agcaacaaat attacacaca ggcctttgtt aacagcgtac tgattgctgt cagctccagt
     5521 gtgattgggt taatcgggac gtttatttta tgtttatgct taatgaatct atcgactaaa
     5581 ttgcaggaga aaatcacctt tgtttccaat ttggcagcta attttgctgg gattccgctg
     5641 gcattctctt ttattatttt gttggggaat gtaggtgtgc tgaaaatgat tttgccattt
     5701 ctagcggact tcaatttgta ttcttggtgg ggattgacca tcacgtatac ctatttccaa
     5761 attccgttag gggtcttgtt tttgtatccc agcatgaagg aagtgaaaaa ggaatggctg
     5821 gagtccgcac aattgctggg cgcttcatca gcgtatgctt ggttcaaggt ggctttgcct
     5881 tttttgcgac catcgattgc cagcaccttt gtcatcttat ttgctaatgg catggggacc
     5941 tatgaaacag cgtatgccct gaccagcagt aatgtaaatc ttttaacgat tcgaattgcg
     6001 gctttagtgt cgggagatgt gttcgccaag cctaatttag gcagtgcgtt ggcagtcgct
     6061 ttaggtgtcc tgctggtaac ggcaatgttg attattcaaa agaaaggcaa ggtggtgcag
     6121 acgtgaaaaa gttaataaaa ccgattttgt tctgctttgt cctgtattac ttgctgccga
     6181 ttattggaac gattttgtat gccagctcca ctaaatggtc aaaatcgctt ttacctagtg
     6241 attttacctt gcaatggttc caacagctgc tgacggacag ggaatttatt gctgcggtgg
     6301 gtcgctcact tttattagca ggtgtggtct tggtgacgat tctgttgttg atgattccca
     6361 ccattatttg gattcatttg tatttccctc gtttgaatcg ttggctggaa aagctgctcc
     6421 tgctgccgta tgctttacca ggagtgattt tggtaacggc tttgcttcga acgtatgctg
     6481 aaactggtat cccaatgttt gtagtgttgg taggtgcatt gtttattacg gcgttgccga
     6541 ttgtctatct tagtcttaac aaccagatgc gcttaattaa tctgaaggaa ttagtggatg
     6601 cagcagaaac cttgggcgcc ccgatgtcta cgattattat ccaggtgctg tttccaaaca
     6661 tccgtatcgg tgtgacccta gtttctctga tgattttttc ttcggttttt ggggagtaca
     6721 tgctgacgaa cctgttgatt ggcggtcgat ttcagacggt acgcatctat atgctgcggc
     6781 ggatgaacga aaacggccat ttggctagcg ctgtgatggt tttgtatttg ctgtttatgg
     6841 tgggaattgc tttaactacc tttatgctga cttatcgaca aaagcaacag ctgtccctta
     6901 agcagacgag ggaagagaag cagtcgaaaa agaagccctt aaaggagttg tgacggaaaa
     6961 tgtttttaga aatacatgat ctcaatctgt tttttgatga aaaacagatt ttagctattg
     7021 atgaaattca gattgaaaag ggtgagctgg ttactttact aggtcccagc gggtgcggaa
     7081 agtctacgtt gctgcgctgt atcacgggat tggaacaacc aaagagcggt gagattgtgc
     7141 tggacaatga gaatattgcc gataagccta cgaaggatcg caatatcggc tttgtttttc
     7201 aacagtatgc attgtttcca actatgactg tttttgaaaa tgtagccttt ggtttgaagg
     7261 taaagaagct gagtcctgag gtgattcagg aaaaggtttt tgagatgcta tcattggtgg
     7321 atatgacgga gcaggcagat aaaaatgtcc agtttctttc tggcggtcaa cgacaacggg
     7381 tggcactggc tcgctcattg gtcactgaac cgaaagtcct gctgctggat gagccattaa
     7441 gtgctttgga tgcccgaatt agaaaacagc tgcagcggga tttgcgcgct atccagcaat
     7501 cgctagggat gacgatgatt tttgtgactc atgaccaaga agaggcgatg cgaatcagtg
     7561 atcggatttt tgtgatggaa gctgggcggg tggctcaggt ttccacctcg aaggaattgt
     7621 atcagaatcc tcagagccga tttgttgcgg aatttatcgg caactataat cgtttcgaat
     7681 ggtatgagct gaatcagtat acccacgagt tttccgctaa gggcaatcgc tgcatttatt
     7741 atttaagacc ggagctgatt caatttgaac cggttcctca gggggttaag attccggttc
     7801 tatggaagga atcatttatt ttaggcaaca ttcaacggta tgtttttcaa acgctggagg
     7861 gcaaagaaat tttagtggat cggttgaacg atcgggaaga gaaaattagc gatgccttat
     7921 acattcagct gaaagatatt ctagcaatcc ctgtggaaat tgatactcag cattttgcac
     7981 aacaaagcta gtgtatagtc ggcaaacatt tctggctctt tgtcaaatag gactgataga
     8041 gtgatataag aacatctaag gtagaattga ttttctgctt tagatgtttt tttatgttta
     8101 ataagtgatc agatgattga ttaagaaaat tctggttctc atcctaaccc gtaagctatt
     8161 cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tgccatttga gtaaggcaac
     8221 tctaaggcta aacgaatgcc ggattcatag tttataaacg ctttttttat atgatgcagt
     8281 tctcttggaa ccgacttggg cattgttttt acaagctgaa agaagatgtc cgcttctttg
     8341 tcataaaaag cttgaagaat ttcttgatag taagcataag ctattcgtag ttcatcagaa
     8401 gtagaaagta gacgttctac gacttcactt tcggttaaat aggcccaacc aaaattacgc
     8461 cattttgtcc atttatcata aacaagcgtg tcctgtcgtt tgatcagaag tcgagataaa
     8521 gccttcactt gtcgatagtg tttggcttgt attggatcgt ttcggtcgaa gcttttcatg
     8581 actcatagtc aaatatcctt aaaactgcga atgaggtgct tgacgatgtg aaagcgatcc
     8641 acaacgagtt tggcatgagg aaagcactct tttatcagca aagcataaga ggcgttcata
     8701 tctgttacga gtatttttac gtttaaacgt gcacgtcgtt caaattgcat aaaataagaa
     8761 atgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     8821 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atctaccaat
     8881 gaacagcgag gcaaccaatt tattttcacg tttgtcatgg ggagcagaga agcgagtgtt
     8941 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     9001 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     9061 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     9121 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     9181 tttccgttct taacgatcag cccatgttga ttcacctgtt tacactgagg acagggctga
     9241 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     9301 tcgacatgag tgatttgaat gtttccatct ttgattccta gtaatagttt gataagatga
     9361 agatcaggca tacagaacgc tcctttgatt gtgttgtggt gattcaattc taacggagct
     9421 tctgtatgtt ttgttttttt atgctcaaaa ggactgatag aatgatttac tatcagtcct
     9481 agaaattata gcgccacatt tctttcacct ttgacttttc agacggcagt ttttatgctg
     9541 atactgtaga gagagcagga cacagctttt gcttgttttg ggtaaggggg aaagaagatg
     9601 accaaagcac ttatttttga ttttgatggg acgatgattg acagtgaatg gatgttttac
     9661 gagagtattc atcactattt actgaagcct atttactgga gcagttcggc tataaaattc
     9721 cttttgcaga ctatcaacaa ggtgttggga cggcagcaga actgtccttt tatgaaggga
     9781 taagtcaagc ggttgggaga ccagtggatg ctgaacattt tgagcagcgg atcagcagca
     9841 ctggaaaatc ggagtagtct caattctgaa ctgcgggagc tagactattt ttttgaagca
     9901 catccgatga ttaaggaaaa aattgattcc tttgtgacga tcgatgatct tcaggtcggc
     9961 aaaccagatc cagaaggtta tttgttgtgc ttgaaacggc tgagggttga acaggctgtt
    10021 gtagttgagg atagtccagt cggtgcccaa gcagcaccgc atatgacagt tgatgtacaa
    10081 gcgttggatg cagatttttt cgcctttagc gggcataaaa tgtgcgggcc gacaggaatc
    10141 ggtgtattat atggcaaacg tcaattgtta gaacaaatgg agccagtcga attcggcggt
    10201 gaaatgatag attttgtcaa tctttacgat agttcatgga aagagctgcc atggaaattt
    10261 gaagctggta ctccgaacat tgcaggagca atcgattact tgaatgagat tggtatggag
    10321 aatattcatc gttatgagca agaactggtt gcctacgttt tacctaaatt acaagcgatc
    10381 ggcggtatca ccatttacgg accgcaagat cctgaacatc atactggcgt ggttgctttt
    10441 aatttggatg gcatccatcc ccgtgatgtg gcgactgctc tggatatgga aggtgtcgct
    10501 gtacgttcag gacaccattg tgcacaacgg ttcatcgacg atttctgttt gactaattgg
    10561 tcgtttaaac agtcgatgat aatgccgttt gagcggctcc aatgtcgtgg aatctttgag
    10621 taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag attacgtgat
    10681 tgattttcgt acagttctat gagaatcgcc tgcttcagtt cctttgttag ttgatgatgt
    10741 tcatcaacta agtccgtttt cgcagaaaag gtctgcccac aatcatagca tagaaaacgg
    10801 gtacgtttta attctaaaat agtcaacttt tctttgactt tcaacatctg agtacgtgtc
    10861 gtataggaac cgttgcggat aatacgaatc gatccacagt gttcacaatg ggaaggtgag
    10921 tcatccaatc tccctttaat aaactgcgct tgaacgcctt tatattcttt ttcaatcagc
    10981 cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct agtatgatta
    11041 tccatagagc gactcctttg gtagggtgat gttttggtcg actaaatttt accaaaagtg
    11101 agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct tcgattttcc
    11161 aacaacacaa aatattatag aagccttttt tctaaaggat ttcaaggtgt ctgtttgcat
    11221 ttattaaaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
    11281 agccataata tgctgtataa tatctagtgt ataggcttaa gtggaggtat atatgaaaat
    11341 attaactgtt gaagatgata atatgataag agagggaata agtgaatatc tttcagaatt
    11401 tggatatact gttattcaag ctaaagatgg aagagaagcc ttgtcaaaat ttaatagcga
    11461 tataaatttg gttatcttag acattcagat accttttata aatggtttag aagtgttgaa
    11521 agaaattaga aagaaaagca atttaccaat tctaatcttg actgcattta gtgatgaaga
    11581 atataaaatt gatgcattta ctaatttagt agacggatat gtagaaaagc cattttcatt
    11641 gccggtctta aaagctagaa tagattcttt aattaagaag aattatggac atttagagaa
    11701 gtttgaatat aaggatctat cggttaattt taatagctat acagctaaaa taaatggtga
    11761 agaaatagat gtaaatgcaa aagaactaga agtattaaaa tgtttattgg ataataatgg
    11821 acaagtgtta acaagaatgc aaattattga ttatgtatgg aaagatagcg aagaaactcc
    11881 ttatgatcga gtaatagatg tatatataaa agaacttaga aaaaaat
//
LOCUS       DAFLWZ010000078        11609 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000078 DAFLWZ010000000
VERSION     DAFLWZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.080"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(105..629)
                     /locus_tag="L1V38_002318"
     CDS             complement(105..629)
                     /locus_tag="L1V38_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1316850.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V38_002319"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V38_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBN1316851.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V38_002320"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V38_002320"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBN1316852.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="L1V38_002321"
     CDS             complement(2351..3031)
                     /locus_tag="L1V38_002321"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1316853.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="L1V38_002322"
     CDS             3157..4026
                     /locus_tag="L1V38_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1316854.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="L1V38_002323"
     CDS             4052..4567
                     /locus_tag="L1V38_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316855.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="L1V38_002324"
     CDS             complement(4614..5207)
                     /locus_tag="L1V38_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1316856.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="L1V38_002325"
     CDS             complement(5232..5411)
                     /locus_tag="L1V38_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316857.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="L1V38_002326"
     CDS             complement(5488..5997)
                     /locus_tag="L1V38_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316858.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="L1V38_002327"
     CDS             complement(6093..6473)
                     /locus_tag="L1V38_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1316859.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="L1V38_002328"
     CDS             6803..7552
                     /locus_tag="L1V38_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBN1316860.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="L1V38_002329"
     CDS             complement(7736..9013)
                     /locus_tag="L1V38_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316861.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1V38_002330"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1V38_002330"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBN1316862.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="L1V38_002331"
     CDS             complement(9935..10879)
                     /locus_tag="L1V38_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBN1316863.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="L1V38_002332"
     CDS             complement(10881..11567)
                     /locus_tag="L1V38_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBN1316864.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3307 a         2461 c         2044 g         3797 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaa
//
LOCUS       DAFLWZ010000079        11479 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000079 DAFLWZ010000000
VERSION     DAFLWZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.081"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..256)
                     /locus_tag="L1V38_002333"
     CDS             complement(<1..256)
                     /locus_tag="L1V38_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316865.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKL"
     gene            550..1365
                     /gene="thiD"
                     /locus_tag="L1V38_002334"
     CDS             550..1365
                     /gene="thiD"
                     /locus_tag="L1V38_002334"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBN1316866.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1694..3145)
                     /gene="cls"
                     /locus_tag="L1V38_002335"
     CDS             complement(1694..3145)
                     /gene="cls"
                     /locus_tag="L1V38_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1316867.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3486..6152
                     /locus_tag="L1V38_002336"
     CDS             3486..6152
                     /locus_tag="L1V38_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1316868.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6516..7268
                     /locus_tag="L1V38_002337"
     CDS             6516..7268
                     /locus_tag="L1V38_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1316869.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7290..8444)
                     /locus_tag="L1V38_002338"
     CDS             complement(7290..8444)
                     /locus_tag="L1V38_002338"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBN1316870.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8629..11070
                     /locus_tag="L1V38_002339"
     CDS             8629..11070
                     /locus_tag="L1V38_002339"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBN1316871.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11227..>11479)
                     /locus_tag="L1V38_002340"
     CDS             complement(11227..>11479)
                     /locus_tag="L1V38_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1316872.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3706 a         2029 c         2440 g         3304 t
ORIGIN      
        1 agagtttatg acttcttgga aattcttttt caatcagttt tttcatctgt ttatgaaatt
       61 cttttttttc agtaaacata aaggtttggg tatcgtaacc ttcttcatgt aggaaataga
      121 ttattccttt ttctgtgttt tgcgtataag cttttatact cctgtctttt ttgaaagaac
      181 agatcgtata gccatctatt tggtctggta gtcgtttgat tttcttcaaa atgacttttt
      241 tatcctcaag tttcattttt ttcacctgac tttatttttt tcatatggaa atcatagcgc
      301 ctttggttat atgaaaacaa gaaggatact gaaatatata taaatcaaat agtggttatt
      361 tattattaga atagcgaata caaataaacg accactattt tctgatttat tgcaaatgtt
      421 ttttcaaata aatttgatta ccaagaaaag gtagtggtat atttactgag ggatactttg
      481 aaaaacatat gatagaaaca gtaacagtat tatgaaaaat ctttttataa aaatggagga
      541 atcgatttga tggaagatca gtatgtacaa gcaatgacga tcgcaggatc agatagcgat
      601 ggaagcgcag ggatgcaagc agatatgcat acattcttta caagaaatgt ttacggtgtt
      661 tctgtcatga ccgcatgtgt tgcaggtaat tcttacggaa tcggagcaag tgtgacattg
      721 ccaacagatt ttatcgacaa agaatttgaa ctgattgcga aggactttca aatacgtgca
      781 gctaaaacag gtatgctagc agattcaaag ttgattgaga cagttgtaaa aaattaccaa
      841 aaatatgatt ttggaccatt agtcgtggat cccgtaatcg taacgaaaca tggaaatctt
      901 ttactagaag aatctgcttt gcaaagcttg aaagaaaagc ttgtcccttt ggccgaagta
      961 ctgacaccta atttttatga agcagaaaag ctgactggac ggacattagc agctgaagaa
     1021 gattttgtgc aagcagcaaa agaactgcaa gatatgggtg caaaaaacgt tatgatcaaa
     1081 ggacatcatg ctaaaaatgc gcagcaagaa acagtcaatg actacgtatt gttcgaatca
     1141 ggaaaatcat tttggttaaa tgcaccattt tatcctaccg accggatcaa cggaactggc
     1201 gattcgctat ctgcatgtat tgcagctgag ttagcgaaag gaaaaacagt tgaacaagcg
     1261 atccgattgg caaaagacta tgtaaaccgt gcaattcgtg aagaaataaa tgtagggcac
     1321 aaatatggcc ccatcaatca ttgggcagct ggtgaattag agtaaaagaa agaagttgtg
     1381 aaaaagttgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt
     1441 taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
     1501 cgtgagcctg ccgtccagct ccgagtcaca aggaacaagt tcaaaaaaca gcttctcatg
     1561 tttgttgaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttgttcggaa
     1621 gaagggactg tgacaagatt tttgtcacag tccctttaat cttagtatat ttttctctac
     1681 ttgaataaaa aaattatagg attggagaaa ataatcgaga aatttgttgc ttgaataata
     1741 gccagttaga catttccttg actgtttcag ttgtcatgga tgaacaatgt gtctcatctt
     1801 ctttgaactg agtagcaagt tcttctaaaa actcaggatc gtaaatgaca gcacttgttt
     1861 caaaattcaa tcggtagcta cgaatatctt gatttgctga acctaccatg cagatttcat
     1921 catccattat caatgttttt gcatggagga agccgttctc atagacaagg atttgtacat
     1981 tttccttgat cagctgccga gcataatatt gtgttgctcg ataaataaaa ggatgatccg
     2041 gtttgttggg aatcatgatt ttcacatcta caccagaggc agttgcgatt tttaaagcag
     2101 caatgacact ttcatcagga acaaggtaag gtgtctgtat ccaaacacgt tttttagcag
     2161 aagtaatcaa tttgataaat gaaagcttga tttgttccct ttcgttattc ggtccgcttg
     2221 aaacaagctg gatggatgta tcagcaagct tagattcatc tcgatctgct tttttaaaga
     2281 aataattcaa atgatagccg accttttttt cttcaggtac cgagacgttc cagtctgtta
     2341 agaagcgaag ctggagcaaa gaagaagcgg caccgaaaat ccgtatatgc gtatcgcgcc
     2401 aatagccgaa tttttttgtt gtatttacat attgattggc aatattgaaa ccaccggtat
     2461 aactaatctt tccatcgatc acaacgattt ttcggtgatc atggtaattc aatcggaaac
     2521 gaagtaatgc cctttgtgag gtaacaaatg tatggacatg tccaccattt ttgattagac
     2581 gattgaaatc ttttgctttt gtgccatgag agccaaatgc atcatataat attcgaactt
     2641 ccacgccttc tgcggctttt tcttctaaaa catgtaagac ttgctggccg atattatctg
     2701 tcacaaatgc gtaatattcg atatggatcg aatgtttggc tttttttaga tcttgaagca
     2761 gtgaatccaa tttctcttgt ccgtctgtga gaagagtgac agaattcatt cttgtcagcg
     2821 gcatacgatt taatgaagag aagaagtcaa caaattgctg tttgtcttta tcgcccatgt
     2881 caggatcgta atgttcaatg gtatctcctc taaaagactg aaagttttct aattctttca
     2941 agtcactttg tcggagatag aattttttct tatccgttaa tccacgtccg aaaaataaat
     3001 ataatacaaa gcccacccca ggaagggcaa acaatactaa gagccatgcc caaatggctg
     3061 ctacatctcg gggtttgatc aaaatagcca ccaaagcaat aagtgcattt aatagataaa
     3121 gggcggttat aatactagat accacaaaaa tgttcctcct tacatacaat aacattagta
     3181 tagcatgata gaagaaagaa gcctaccaag gtgaatatac ttttcactcc tttcatgaaa
     3241 atgtaggtaa atcgggctaa agtagttgct ttttgtaggt taataaggta ggatattagt
     3301 acagttgaat atctccttag gggagtaacc ggcaacgttt gttgcgataa tatcaacagt
     3361 aagttaacca aatggttttc tggtattgta tgaaatggtg agacctaaga caaatgcgta
     3421 tttgtcttag gtctcttttt tttcagacag gactagggcc aagatcaaaa aatgggggat
     3481 gaaatttgga aaacaaggaa caagcacaac aagcggtcta taaagaaacg atcgactcgt
     3541 tgatgcagca aacgcagagc tcaaccgatg gattgagcac cacgcaagcg aaggaaaaat
     3601 tagaaagaga tggcttgaac cagctaaaag aaaagccgaa gaagccaact tggaaattgt
     3661 tcttagaaac tttcaaagat gcaatggtta tcgtattgct gattgtcgca ctgattcaga
     3721 tggtcatggg tgactacatc gaattcttag ttatttttgc agtattgatg ttgaattcta
     3781 taatcagtgt tgtccaaaca aaaaaagcag aaggttcttt agaagcgttg aaaaaccttt
     3841 cagcgcccga tgctcgagtg attcgtgatg gtaaggaaaa aacgattccg gcaaacgaac
     3901 ttgtggtagg agatatcgtg ttgttagacg caggcgatta tgtacctgct gatggacgtt
     3961 tactagatgc gggatcatta aaagtagatg aaggtatgct gacaggagag tcgacttctg
     4021 cagaaaaaga agtaacggat atcacaagta cggtaccaat cggagatcgt acaaatatgg
     4081 tattcagtgg aacgatcgta acttacggac gcggtaaatt cttagtgact tcaactggga
     4141 ataatacgga gatcggacaa gttgctggcc ttttggaatc aacaactgag caagtcactc
     4201 cgttacaacg aggtctggat aaattcagta aaaaactaag tttggctatt ttggcattgt
     4261 ctttattgat tttaggtatc caactgtttc gtatttatct tggagaaggt acaggagata
     4321 tgactgcaga tatcgtcagc gcagtgatgt ttgccgtagc cgtagccgta gctgctattc
     4381 cagaagcatt acagtctatc gtaacaatcg tgttatcttt gggaacgaat aaaatggcaa
     4441 aacgtcatgc cattattcgg aagcttccag cagttgaaac acttggttcg acaagtatca
     4501 tctgtacaga taagactggt acattgacac aaaacaaaat gacagttgtt gactactttt
     4561 taggtaatgg cgatactggg gatttcacaa atgacccttc aaaatggaca gctgacgaac
     4621 gtcgcttgat cgaaatcagt gttttagcga atgatgcatc gatcagtgaa gacggtacta
     4681 aattgggcga ccctacggaa gtagcgttta tcgactttag tgaaaaatta aaccagcctt
     4741 atcaggaaat ccgaaacaac tacccaagac aagcagaact tccttttgac tcagatcgaa
     4801 aattaatgtc tactggacac acaattgata acaaaaatta cttgtttgtt aaaggcggac
     4861 cagatatcgt cttccaacgc agtaaaaaag tattgctaaa tggtgaagtc gttccgatga
     4921 cggatgaatt gatgaaaaaa ttccaagagc aaaatgaagc tttttcaaca cgcgcattac
     4981 gtgtactagc ttttgcttac cgtccacttg ataattttga tttatcattt gaagatgaag
     5041 acgatttgat ccttgttggt ttgcttgcta tgatcgatcc tccacgtgct gaagtgactc
     5101 aggcggtaac agaagcaaga agtgcaggaa tcaaaacaat catgattact ggtgaccaca
     5161 aaacaacagc tgttgctatc gcaaaacaaa tcgggatttt tgaagaagga aacctggctt
     5221 tgaccgggac ggaactagat gaattgacag aagatcaact aaacgaagtt ttagaaaaag
     5281 tcactgttta tgcacgtgtt tcacctgaga ataaaattcg tatcgttcgt gcttggcaaa
     5341 ataaaggtca tatctcagct atgacaggtg atggtgtaaa tgacgcacca gcattgaaac
     5401 aagcagacat cggaattgct atgggaacgg gtacagatgt ggcaaaagat gcagcagcga
     5461 tggtattgac ggatgataac tttgcttcta ttgtcagcgc agtagaagta ggacgtaatg
     5521 tgtttgataa tatcaagaaa gctatttctt atctatttgc aggaaattta ggtgcgatca
     5581 ttgcgatcat ctttgcctta gttgctgact ggtccaatcc atttacagca ttacaactgt
     5641 tgttcatcaa tttagtcaat gattcactgc cagcaattgc attaggtaca gaaaaagctg
     5701 aacctgctac gatgaaccgc ccgccaagag atccaaattc aggaatcttt acggacaaaa
     5761 cattgatttc tgtaacgtat cgtggtgtgc tgattgggat tgctgttatc tttgctcaat
     5821 ggcttggcat gcagcattca cctgaattcg gtgtagccat gtcattttca acattgattt
     5881 ggtgtcggac attgcaaaca ttcccagcac gttcaaacac acaaacagct atccaagcag
     5941 ggttcttctc taacagaagt gtcttactag ctgtagttgt atgtagcgcg ctttactgct
     6001 taacaatgat cccaggactg aaagaagtct tctctatccc atcagcattt ggattgacag
     6061 aagtctttac atgtatggga atcgcacttg tgacaattgt tttgatggaa atcactaaat
     6121 tgatcattgt acgagtacaa ggaaataaat aaaacgaatc aacgaggttg tgagcctgcc
     6181 gtttaattct gagtcacaag gtgcaatttc aacaaacagc ttctcatgtt tgttgaatat
     6241 tgtgacttgt gaccgaagag ttggcaggag aacaccgttt aaggaagaag ttgtaaaatc
     6301 agcattttga gctaatactg agggtcatct gattggacac tgtttattcg gaaagaggga
     6361 ctttgacacg actttggtca cagtcccttt ttttatttat gatagacgga aagccaatca
     6421 ttttattatt catcaaaaga gatagaatag ataaaagagg agaatgattt attccgaaaa
     6481 gtgaaaacat ataacaaaaa attagaggaa atcaaatgaa tgaaaaagaa tgggatgaat
     6541 ttgctgaaga atattatgaa atccagcaag aatcgcaagt aactattgct gaagatgtaa
     6601 aaaattatct gaaaacggag aaagtcctgc ctgctgaaac agcagcagac gttgctggag
     6661 gatctggcag atttctttcc ttagcaaaag aaattaatcg ctatgatttg atcgattttt
     6721 cttcaggaat gctagaaaat gcaaaaaaag aagcagaaaa aaatgagttg ccaaatgttt
     6781 cctttatcaa acagtcgtta gaagaattta tccaatcaaa tgagacatat gaaatggttt
     6841 ttacagcagc aaatccagca ttggtacatc ttattcaatt agaaaaattg atgaaaaagt
     6901 caagcaaatg gtgcgtgata atcagagtag tggaatcaat cgatgatgtt ttttatccta
     6961 tcgaaaagca actaggaatg atagaagaag atcctaatac atcgccagtt gtaatggatc
     7021 aatttgaaac atacttaatt gatgaaggat tcaaagtgaa gaaaaaagat tttacttatt
     7081 ttacacagga atcaattact gaagaattga tgaagctata ctatgacgcg tacgcaaaag
     7141 atcctgttgt gaccaggtac attcgcaaac tattcagtga aaaacgagaa atccttagta
     7201 cgactaagct gacctataga ctgctccttt ggtccgcaga taaaaaaaga acctttcacg
     7261 actcgtgaag ggttcttttt atgattttat tatattttgt agtaacgaat atcattttcg
     7321 atctttgtaa tcgaaaaagg tacatctgaa gtatattctg cacattctcc gtgttcagga
     7381 agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga tccgtgttcg agaatctagc
     7441 atctcttgat gagattgtgc gaagagatat tcttgatagt tttcttccag ataacctgta
     7501 aaaaattcac ttactgcacc agaaccgtag ctgaatagac cgatgcgatc tcctggctgt
     7561 agtgatttcg aattttccag tagagaagtt agccccaggt ataatgaacc agtgtaaaga
     7621 ttaccgattc gtcggctgta acggatgctt tcttcatagc gagccataag acgttcctga
     7681 ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct tttttcccat cttagtatac
     7741 ggaatatgga aagcaatcgc ctgataatct tcgagtcctc gacccgacaa ttctttatgt
     7801 cgattccaaa ctttttggaa tgattcgata tacgtagaat tagataaagg accatcaaca
     7861 acaggaaatt cgctataatc tggacgccag aaatcataga tatcttctgt cagaaatacg
     7921 ctgtcgtctt caatcgataa aatacgcggg ttttgagtga tcatcatcgc aacagcaccg
     7981 acaccttgcg tcacttcacc accgcttgcc aagctgtaac gagcaatatc acttgctatg
     8041 actagtactt ttcgttctgg atgatttttg acatattctt tcgccatgtg caaagctgcg
     8101 gtgccaccgt agcaagcctc ttttacttca aaagaacgag caaaagattg gattttcagt
     8161 aaatggtgga taattaccgc actcgctttt gaatgatcaa tcccggattc tgttccgacg
     8221 atgaccatgt cgattagctc acggtctttt tctgttacga ttttgctggc agcatttgct
     8281 cctagtgtaa tgatgtcttc atttgcacga ttgactgcca tttggtcttg accaatccct
     8341 atatggtatt ttgcaggatc atccccacgg ctttctgcca actctgtcat atctaaatat
     8401 aaattaggaa taaaaaagga aagacgatca atccctattt tcatttcaac acctctttac
     8461 ttatgataaa aaacttactt tactaaggta tcataaaaag attaaaagaa atataaaaaa
     8521 gagaatattt aaggattgtt aaaatttaat cttagaaaaa aataactgga acaagagcta
     8581 tttgttttta cagcaaagaa tggtatattt ttgtaggagg tggcttactt gaaagaagtc
     8641 gttatgatag atgctgcaag aacgccgata ggaaagtatc gcggaagttt aagtccattt
     8701 actgcagttg aattaggcac acttgtgact aaaggattat tagataaaac aaaactgaaa
     8761 aaagataaaa tcgatcaagt aatatttgga aatgtcctgc aagctggtaa tggtcaaaat
     8821 gttgccagac agattgcttt gaacagcggt ctccctgtag atgtcccagc aatgacgatc
     8881 aatgaagttt gcggatctgg tatgaaagca gtgatcttag cacgccagct gatccaatta
     8941 ggtgaagcag aacttgtgat agccggcgga acagagagta tgtctcaagc acctatgctg
     9001 aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa tttccagtat ggtcaacgac
     9061 ggattgactg acgcattttc aaatgcacat atgggattaa ccgcagagaa tgttgcaaca
     9121 caattttctg tgagcagaga agagcaggat cgctatgcct tgtcgtccca gttgaaagca
     9181 gcacatgctg tcgaagccgg tgtattttct gaggagatca tcccagtcaa gatttctgat
     9241 gaagacgtgt tatctgagga tgaagcagtt cgtggaaata gtacattgga aaaactgggc
     9301 acgttacgta cagtattctc agaagaagga actgtaacag caggaaatgc ttccccgttg
     9361 aatgacggtg cctctgtggt gatccttgca tccaaagaat acgcagaaaa taataatctg
     9421 ccttatttag caaccatcaa agaagtagcg gaggtcggta ttgacccaag tatcatggga
     9481 atcgctccaa tcaaagccat tcaaaaattg acagatagat caggaatgaa tttatcaaca
     9541 atcgatcttt ttgagatcaa tgaagcattt gcagcttctt ctatcgtagt tagccaagaa
     9601 ctgcagttag atgaagaaaa ggtcaatata tatggaggag caatcgcatt aggccatcca
     9661 attggtgcaa gcggtgcacg tatcttgact acattagctt acggattgct tcgtgaacag
     9721 aagagatacg gtattgcttc attatgtatt ggtggaggtt taggcttggc agtcttgtta
     9781 gaagcgaata tggagcaaac acataaggat gtgcaaaaaa aaaagtttta tcagcttacg
     9841 ccatctgaac ggcgcagtca attaatagaa aaaaatgtat tgacacaaga aactgcgttg
     9901 atttttcagg aacaaacact ttctgaagag ctctccgatc acatgatcga aaaccaagtg
     9961 agtgaagtgg aaatcccaat ggggatcgcg cagaattttc aaatcaatgg caagaaaaaa
    10021 tggattccga tggcaacaga ggaaccatct gtcattgcag ctgcaagtaa tggtgcaaaa
    10081 atctgtggaa atatctgcgc agaaacacct cagcggctga tgcgagggca aatcgttcta
    10141 tcaggaaaat cggagtatca agcagtgatc aatgcagtta atcatcgaaa agaagagctg
    10201 attctttgtg caaatgaaag ttatccttca atcgtgaaac gcgggggcgg tgttcaagat
    10261 atctctactc gggaattcat ggggagtttc catgcatact tatctattga ttttttagtg
    10321 gatgtaaaag atgcaatggg cgctaacatg atcaactcga ttcttgagag tgtggcaaac
    10381 aagttacggg agtggttccc tgaagaagag attctattca gtattttaag taattttgct
    10441 acagaatcat tggcttctgc ctgttgtgaa atcccattcg aacgcttagg gagaaacaaa
    10501 gaaatcggtg aacaaattgc caaaaaaatc caacaggcag gggaatatgc gaagcttgac
    10561 ccttaccgtg cagcaacgca caacaaaggg atcatgaatg gtatagaagc tgtagtggca
    10621 gctacaggaa atgatacacg tgcggttagc gcttcgatcc acgcctacgc ggcaagaaat
    10681 ggattatacc aaggattaac agactggcag atcaaagggg ataaactagt tggaaaacta
    10741 acggtgcctt tggctgttgc cacagtaggc ggagcttcca atatcctgcc aaaagcaaaa
    10801 gcatctttag ctatgttaga tattgattca gccaaggaac tagcacaagt aattgctgca
    10861 gtagggttag ctcaaaacct ggctgctttg cgtgcattag ttacagaagg aatccaaaaa
    10921 ggccacatgg gacttcaagc tcgttcatta gcgatctcaa ttggggctat tggtgaggaa
    10981 atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga tgaaccagca gacagctata
    11041 caaatattgg aaaaaatccg ggaaaaataa aaaagcaata tctttagaag aataaagcaa
    11101 gatttacagt tattttattt actgcagatc ttgctttttt ggctcttcgt caaattgtgt
    11161 tggcgaagac aaatttgaat aaaacttagt ccgatatgcg gcgcgttctg tgcgccgcat
    11221 atttttttag ttttcaaaga tcagaccttg ttgtaaatag atccgtgccc gaaagttata
    11281 aaagttgcga taaccaaacg caattcgttt aatcagcttg atcttgttat tcagcccctc
    11341 agtgacgccg tttgagtggg gcaccttaaa ggcatttgaa atacccgatt ggtagcgatg
    11401 gaagatcgtg aatttctttt taaacgactg aggtaacgta gatgaaattg ttttaagggt
    11461 ttcttgaaag ccttccgta
//
LOCUS       DAFLWZ010000080        11446 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000080 DAFLWZ010000000
VERSION     DAFLWZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.082"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(158..643)
                     /locus_tag="L1V38_002341"
     CDS             complement(158..643)
                     /locus_tag="L1V38_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBN1316873.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    733..1078
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1123..1764
                     /locus_tag="L1V38_002342"
     CDS             1123..1764
                     /locus_tag="L1V38_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1316874.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1783..2418
                     /locus_tag="L1V38_002343"
     CDS             1783..2418
                     /locus_tag="L1V38_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1316875.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2436..3251
                     /locus_tag="L1V38_002344"
     CDS             2436..3251
                     /locus_tag="L1V38_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1316876.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3570..5006
                     /locus_tag="L1V38_002345"
     CDS             3570..5006
                     /locus_tag="L1V38_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1316877.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5195..7627
                     /locus_tag="L1V38_002346"
     CDS             5195..7627
                     /locus_tag="L1V38_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1316878.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            7857..8924
                     /gene="rlmN"
                     /locus_tag="L1V38_002347"
     CDS             7857..8924
                     /gene="rlmN"
                     /locus_tag="L1V38_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1316879.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9117..10220)
                     /locus_tag="L1V38_002348"
     CDS             complement(9117..10220)
                     /locus_tag="L1V38_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1316880.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10772..11320
                     /gene="aac(6')"
                     /locus_tag="L1V38_002349"
     CDS             10772..11320
                     /gene="aac(6')"
                     /locus_tag="L1V38_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1316881.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3795 a         1938 c         2473 g         3240 t
ORIGIN      
        1 atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt catactagtt
       61 gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa taaagaaaaa
      121 gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca taaactggca
      181 gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc aacgtagtgg
      241 tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca tcgatcacga
      301 cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta cctgctggaa
      361 cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt tcttttaatt
      421 gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca agatagattt
      481 gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt agggaaaaag
      541 ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag atacccagtt
      601 tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat caccctcctt
      661 tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg taaattacac
      721 gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt ttagagagtc
      781 tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt cgattttctg
      841 aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc tagatgacca
      901 gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg tgattaacgt
      961 cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg actgtgtgag
     1021 gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg tcctcttggc
     1081 atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta tttgattgaa
     1141 gttatgccgc aattattagt aggagcactc acaacattga aattattttt atttaccttg
     1201 attggctcat taccattagg gattgtttta gcattaggat tgtctttgca ttttaagccg
     1261 ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct gttgttgcaa
     1321 ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg tttcgaagca
     1381 gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt tcgtggaggg
     1441 atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt aagtcccttt
     1501 caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc ttctgtaggg
     1561 aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg tttaggtgac
     1621 gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc tttgctaggc
     1681 gtggcaatca tctatcttac attgactggt attctaacaa tcgtaatgaa acaagttgaa
     1741 ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga attgaagaaa
     1801 gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat cattccagat
     1861 gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct tttacgtatc
     1921 ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt accgttcaac
     1981 ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga cttccagcta
     2041 tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt attgaaacag
     2101 acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg gattagtgat
     2161 ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt agcgattgcc
     2221 agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag tgctttagat
     2281 cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga tggggtaacc
     2341 caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca attactaaaa
     2401 gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt tttctattcg
     2461 ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact tcagcagata
     2521 attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat acatttgttc
     2581 ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat ttagccaaag
     2641 cagtctttga acaatatggg attacggtag actttcagcc cattgactgg tcaatgaagg
     2701 aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc aaaacgccgg
     2761 caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa gtgctgatca
     2821 cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga ttaggtgcgc
     2881 aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta aaagagatag
     2941 tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc gatctgaaaa
     3001 gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat ttgaaacaaa
     3061 gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag gattttgcag
     3121 ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc ctagatcaac
     3181 tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa gatgttacgc
     3241 cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct ttttccgaat
     3301 aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc tcacaacctc
     3361 ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat gcaaaaatgt
     3421 agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt tttcacaacc
     3481 tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa aagaggaacg
     3541 attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc tcatttccaa
     3601 aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct tggcaagaag
     3661 atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag acatttaaag
     3721 gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat attgctttaa
     3781 tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg atttttccta
     3841 atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg atcgacgaat
     3901 tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt ccacaagcat
     3961 tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc actcattatg
     4021 cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt ttgaatgaac
     4081 aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt gtgacagacc
     4141 cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct gtcatcaata
     4201 aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat acgccaaatt
     4261 atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa gacctgatgg
     4321 ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc atgaggttct
     4381 tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg ctagaatctg
     4441 ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca ttcaatccat
     4501 taaacggagt tggtgctgga aaaatgaata cgacaggaaa aaaaagttca tcagaagaaa
     4561 ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga acaaattggg
     4621 actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca agccgttacc
     4681 gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg acagaagata
     4741 aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa gccatcaaag
     4801 aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat acagatttgc
     4861 ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat caagacgaaa
     4921 cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac caaaaactga
     4981 ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt acggctggat
     5041 atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt aaaataagct
     5101 gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt actttttttt
     5161 gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac ggcctactaa
     5221 aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac aaatgctgac
     5281 gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa aattaggttt
     5341 tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt accaaatcct
     5401 ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag agttttcaat
     5461 tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct tattattgtt
     5521 acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg ggacgacatg
     5581 ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg gtggtgggat
     5641 gattggagca atcctttatc attttactta cttcttgatt gcacagcctg gaagttattt
     5701 agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg aaggctatca
     5761 gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg aaggtgatcc
     5821 tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc gcgcagaagc
     5881 gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa tatgagaaga aaaaagcggt
     5941 gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata cagagccgga
     6001 gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg cgaatctaga
     6061 gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt cagatgagtt
     6121 gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg aaaatcaaga
     6181 ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc aaagtgatga
     6241 gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa gtttcggtgt
     6301 cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg aagtccagcc
     6361 ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt
     6421 agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga ttggtattga
     6481 agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag cacaaccaaa
     6541 ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac gggtacaaac
     6601 ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta gtgggaagtc
     6661 agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc atgaagtaaa
     6721 actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca tacctcatct
     6781 gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa aagtagtaca
     6841 agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata tttctggtta
     6901 caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa ccttaccatt
     6961 catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca atgaagttga
     7021 agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata tgatcctagc
     7081 tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg taccttccag
     7141 aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt ctaatggggc
     7201 agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga ataaaccgat
     7261 ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc aatttgttac
     7321 agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag ttgaaacgac
     7381 aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga
     7441 aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt acaaccgagc
     7501 agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag aaggaagcaa
     7561 gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg acgataatga
     7621 catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa gacaaggcat
     7681 gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta tgatgtcttg
     7741 tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt attgcattaa
     7801 ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa aatactttgg
     7861 aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt atagaaaacg
     7921 gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta
     7981 atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg gagcatttta
     8041 tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt
     8101 tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa gaatatggct
     8161 tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg
     8221 ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag atcatgatgg
     8281 tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg
     8341 ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat atcatcaatg
     8401 atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt ggattagcac
     8461 acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt tccttgcacg
     8521 cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc ccaattgaga
     8581 aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat
     8641 atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta gcagatctat
     8701 taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca gtcagtgaac
     8761 atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat gtattgaaga
     8821 aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat gcagcttgcg
     8881 gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt
     8941 ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa cttaaataag
     9001 agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac cctcatcaag
     9061 caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc aattatttaa
     9121 ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc tacgtcaaga
     9181 atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat atcatttgtt
     9241 gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt catgtcggtt
     9301 aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa caaatcgaac
     9361 tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc gtgaaggtat
     9421 ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat agcagaatta
     9481 tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc cgaaacgact
     9541 tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg cgtaccataa
     9601 gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc cgtgtagcct
     9661 agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc atcgccaata
     9721 cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt
     9781 acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt atagatgaca
     9841 cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa gactggttta
     9901 gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc gactgcaaac
     9961 aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt tccataagtt
    10021 gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa agctactttt
    10081 attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac ttttgtccca
    10141 tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt ataatttggt
    10201 aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg gttaaaattt
    10261 taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct aagacaggat
    10321 aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc taaaaacgaa
    10381 caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag tatttctacc
    10441 gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt attatatgaa
    10501 aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat aatctatatc
    10561 atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt tcctattttg
    10621 aataaagtgt ttctgtataa ttttttattt tataagtaag ataaataatg aaagaataga
    10681 gatactgatt ggtagctaaa gatttttgag cgagaacatt tcgttttttc aaaaggactg
    10741 ttagaataag caagaacaag ggggaagacg tatgataatc agtgaatttg accgtaataa
    10801 tccagtattg aaagatcagc tttctgattt actgagactg acttggccgg aagaatatgg
    10861 agacagctcg gcagaagaag tagaagaaat gatgaatcca gaacgaatcg cggtagcagc
    10921 ggtagaccaa gatgagttag taggatttat tggtgcaatc cctcaatacg gtatcacagg
    10981 ttgggaattg catccattag ttgtagaaag ctcccgacga aagaaccaaa taggtactcg
    11041 attagtcaat tacttagaaa aagaagtagc ttccagagga ggaatcacga tttatttagg
    11101 tacggatgat ttagaccatg gaacaacgtt aagtcaaacg gacctgtatg agcatacatt
    11161 tgataaagtg gcttccatcc agaaccttcg tgaacatccg tatgaattct atgaaaaatt
    11221 aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc tgggacaaac cggatatttg
    11281 gatggcaaaa acgattattc ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga
    11341 agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat tacttcttga atttttgtga
    11401 aattccaact tatttccgaa gaagctactt ttggaacacc gtgtac
//
LOCUS       DAFLWZ010000081        11293 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000081 DAFLWZ010000000
VERSION     DAFLWZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.083"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            20..583
                     /locus_tag="L1V38_002350"
     CDS             20..583
                     /locus_tag="L1V38_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316882.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(644..1009)
                     /locus_tag="L1V38_002351"
     CDS             complement(644..1009)
                     /locus_tag="L1V38_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316883.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1085..1330)
                     /locus_tag="L1V38_002352"
     CDS             complement(1085..1330)
                     /locus_tag="L1V38_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1316884.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1400..1654)
                     /locus_tag="L1V38_002353"
     CDS             complement(1400..1654)
                     /locus_tag="L1V38_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316885.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1818..2141)
                     /locus_tag="L1V38_002354"
     CDS             complement(1818..2141)
                     /locus_tag="L1V38_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316886.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2328..2401
                     /locus_tag="L1V38_002355"
     tRNA            2328..2401
                     /locus_tag="L1V38_002355"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2362..2364,aa:Ile,seq:cat)
     gene            complement(2786..3283)
                     /locus_tag="L1V38_002356"
     CDS             complement(2786..3283)
                     /locus_tag="L1V38_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1316887.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3323..4132)
                     /locus_tag="L1V38_002357"
     CDS             complement(3323..4132)
                     /locus_tag="L1V38_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1316888.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4466..5323
                     /locus_tag="L1V38_002358"
     CDS             4466..5323
                     /locus_tag="L1V38_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1316889.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5316..6218
                     /locus_tag="L1V38_002359"
     CDS             5316..6218
                     /locus_tag="L1V38_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1316890.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6251..6601
                     /locus_tag="L1V38_002360"
     CDS             6251..6601
                     /locus_tag="L1V38_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1316891.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6650..7573
                     /locus_tag="L1V38_002361"
     CDS             6650..7573
                     /locus_tag="L1V38_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1316892.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7651..8544
                     /locus_tag="L1V38_002362"
     CDS             7651..8544
                     /locus_tag="L1V38_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1316893.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8582..9145
                     /gene="amaP"
                     /locus_tag="L1V38_002363"
     CDS             8582..9145
                     /gene="amaP"
                     /locus_tag="L1V38_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1316894.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9159..9347
                     /locus_tag="L1V38_002364"
     CDS             9159..9347
                     /locus_tag="L1V38_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1316895.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9360..10262
                     /locus_tag="L1V38_002365"
     CDS             9360..10262
                     /locus_tag="L1V38_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1316896.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10294..10536
                     /locus_tag="L1V38_002366"
     CDS             10294..10536
                     /locus_tag="L1V38_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1316897.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10792..11163)
                     /locus_tag="L1V38_002367"
     CDS             complement(10792..11163)
                     /locus_tag="L1V38_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316898.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4002 a         1928 c         2136 g         3227 t
ORIGIN      
        1 cttattttta aaaataactg tgttatatat taaaaaaggc ataatagtta taagcttttt
       61 taaagaatat ttagaaatta ttaattttcg tctgaaaaca aaaaaagaaa gcgttattat
      121 tttagtctat tttcaggggg ggaaccttat gataaaaaaa ctatttttac tatcaatatt
      181 aacgctagca atggcaggtt gttctgactc tggcttagca actgaactga tcacaaaatc
      241 aactgaagcc acgacagagg agttaaaatg tggaaacgat cacagtgact acagaggctt
      301 aaatcgacga tgcatgggaa tattaggcag aagcaattgt aagcatcgat gtagtaatcg
      361 aagaaggtgt agaagaagca acagaaaaat caaaagaaag atcaaaagaa gcaatctgtg
      421 ctgtgcatcg tatacagacg tcgaagatgc ggtactttta aaccacgtca ggagatgttc
      481 atttatgtct agggaagttg gcgatgaacc aaaactagag tacgctttta gttttgcacg
      541 tgaggatgaa gataacccta aaacttacga cattttagct tgatctaaga tggttaaagc
      601 tttttaatga agtaagagga gatagaaggc ttttctagtt atattaggta agataaattc
      661 ctttttgctc caaatttgct aaacattctg ctagataaac ttcatcgtgt tccggataaa
      721 tcggcacgtt gcgctctaca gtaggtaaat caaaaaatgc ttcgcatgat ttgccacgat
      781 acataggatt tttccactct ggtgctgggc tgtaaccacg tttttccatt tcatccatga
      841 caagctgatg atattggaat aatctataag gagaatagtg aaaaacataa tccacagtag
      901 catgtttctt tccccagcca tttcctctta atgcacagca ttcccgatgt tgtcctaaaa
      961 gctgttgacg aggaagcttt gaaatcaatt tttcatgcca taatcgcata gaaatgtctc
     1021 ctttatatat agattgttaa ccttagacgt taaatgaaaa aaccagcacc aaggctggaa
     1081 aaaatcactt cagtttgctt gctgtttctg agcgaccaat taggtaatca acggaaatat
     1141 cgtaaaagtc agcgatatag attaattcaa tgatgcttgg aatttcttct ccttcttcgt
     1201 acttacgata tttgaataaa ggaatactta acgcgctaga aacagctact tgagataaag
     1261 atcggccagt tcttaagaaa ttcagacgac aacgtaaagt atccagtaaa atagcttctt
     1321 cgatactcat ttaatcacct ttcattatag tagaatagtt ataatgacta tagaaagcta
     1381 cacatgcaat caatagtact caatgttttt tatttaaacg tatcaaataa agaatgacga
     1441 tcaataaaga caaaaccagt cctgataatt cttctataaa aacactatcg ggttcaaagt
     1501 agttgtaatt aaaaactttc cacataaagt agatagccgg aagagtcaaa atagctaaat
     1561 aaaaccgttc tttgttccaa ttcataagat aaacaatact tgcgaccagt gcgaccgcag
     1621 gcacccaaaa caaaactctc accaacgtaa tcatgtaacg gactcctcaa cgattcatat
     1681 aataaaagat aacatgttat tgcatacatc acaaatgaaa tgctaggaaa ataaaagaag
     1741 aatagatcaa tgaaaaatga aaaagcagaa cagttttctg ctgataagca ggaactgttc
     1801 cgctgaatgt gtcttatcta tcgagaaaaa atcaatggat tgatatctaa gtaattcaat
     1861 acatataaaa agaggacgat cgcattcact aaaaaggaaa gaatgatgat cccatagcga
     1921 atggaaacat atttaacaaa tacttttgtt tgaatacggg catatctttt tcctttatag
     1981 ctgagcatca tgacaagaag caaaagggta atcacacctt gaaaaatcat tccaataaac
     2041 agaattcctg aggtttgata atttaattgg agaaaataag ctgctgccgc aactaaatcg
     2101 aataaaatcg caataaatgg caaaataatc actcctaaca ttgagaataa ataaaagaat
     2161 aacatttttt ctaaaataag caaataaaaa ttaaagtaac aaaatagtta tgacacaagt
     2221 aaaagaaata agaataacaa tattatttta cttatatttt gaaacttgtg agagtttgtc
     2281 attcgtgcta tagttgaaaa gtaacaaaaa taaattttat ttatgatgta cctttagctc
     2341 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtac
     2401 ataagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa gtaaaaacag
     2461 cttcttatgt ttttacttgg ctgttcttat tactgcagat gcaagctttt gaataccgtt
     2521 taaggaagag gttgtgaaat cagcgttttg acctgagtat tagcttaaca aacggaaaaa
     2581 tagttcctca tattttgccg tttgttaagc taataccgag ggtcagctga ttgaacacca
     2641 tttaagaaag aggtcgtgag cctgccgttt cactctgtgt cataaaaaag ccaatctact
     2701 ttgatagaaa aagcacgtag gactaaaaca gttctgcgtg ctttttttat tgtgtgttaa
     2761 atatcgtaaa tgaagataga tatttttatg attcgacgat agagacgttg aaatctttca
     2821 acagctctaa agcggattct ccgtgttttc tactggagac taacattgga tcaacaaaaa
     2881 agtctgcttc aggaaaagca ctctgcaggc ctatcagatt agagagtaca cacaagtttg
     2941 tttcaatccc gactacttcg atctcttttt gttcttcttt gctttcaaat aaagtttcct
     3001 ggatttcagc taaagtttca ggtggaatcg taaagtaata ctttttaatc actcgttcat
     3061 tttcttgtgg agaaagaaga gggatcaatt gcaaatcttc tcgttcttct tctttgtcct
     3121 tcagttcaac tggtatatcc cgtgtgaaga gaatatattc attattttgg cgtgctttag
     3181 ctaatctttg agcaatacgt tctgccaatt gatctgactc tggaatataa aattcgctgt
     3241 ttggatcaag aatatgattt tgcatatcaa taataactaa cattttcttt cctcctacat
     3301 tcatatcgtc attttattct ttttaataga agttttttaa aatataagca acaccagctt
     3361 cttcattcgt cagtgttact tggtttgcaa tttcttttac ttgtcgctgt gcattcccca
     3421 tcgcaatact caacccgctg taattcaaca tagcaatgtc gttttcttga tcgccaaaag
     3481 ccatgatgtc actcgattcg attccaaggt aatccgccag aaaaacaagt gaatgagctt
     3541 tagtgatacc tgtaggcgtg atttctaaga aatgcggatc agagaatact gattggatac
     3601 catctgcttg cagatctctt tgtagcttct gtagtttttc ttcactctta tctgttaatg
     3661 ctaatttaag atagctaaga gaaggatctt ccaacatatt taaaatttga tcaaaagaat
     3721 ggttctgtaa attgaaatgt tcataataag ggtcatcttt gactagattt gattcatcga
     3781 atgtcagctg atcatcttgg gtttctcggc tagcaatgat ggatattttc gcttcttgag
     3841 catagaagaa ggcttttctc agtgtatcgc tatctatttt tgaacgtctg agaactttcg
     3901 ccatttttcc atccttcatt tcagcaatca gtgaaccatt ggaagaaatc aaatagccac
     3961 cgattcctaa ttcggaaaaa atatctttag cagaaatgct gttccttccg gtagcgacgg
     4021 ttacgattcc gccattttca tcaaatttcc gaagtgcttg gatattttct tctggtatct
     4081 ttccatttcg atcaagcaag gtaccgtcta aatcaatcgc tgctagtttc attttatctt
     4141 cctactttct ttttacatat ctattttcct gttaccttaa gattaaatga gaatttaaaa
     4201 aaatgaaact aacttgcttt gtcattatga attttttcaa aaaacattct taagaaaaag
     4261 gtggctatat atagtagttt ttggtcaata cctttgaata aaaagccatg aaaaacgaat
     4321 agttagcgct taccgatgcg ttttgtgata aaaaaatttt aaaatattca atgaaaacaa
     4381 agcatatatt ttgctttaaa accaaatgag gaatattcta gatgtagaac aggttagaaa
     4441 aagattagaa aaaggagtga ttttgatgga gaagagatac ggcgtagttc ctgtggtaac
     4501 tgcttcagac gaaaattatg ctccttactt gagcgtgatg atcgcaactg cattagaaaa
     4561 ttgcaataaa acaagacgca taaaatttta tgtgattgac gatggtctat cagaatatag
     4621 taaagaagga ttggaagaaa cggtaaataa atattcaagt aatgcaagta tccaattcct
     4681 gacagtggaa aaagatatct acgaagactt cctagtcagt gaccatatca caactaccgc
     4741 ttacttaaga atttctttac caaacttatt agctaaagag gattataaga aagtccttta
     4801 cttagattca gatgtgttag tactagacga tatcgtaaaa ctatatgatg agccgttaaa
     4861 tggaaaaaca atcggcgcta ttatcgatcc aggccaagtg aaagctttgg aaagattagg
     4921 aatcgattcc gatgacttgt acttcaattc aggagtgatg gtgattgaca ttgatcaatg
     4981 gaataaaaaa gaaattacag aaaaaactat ccattacctc agtgaaaatg gcgatcgaat
     5041 catctatcac gaccaagatg ctttgaatgc tgtactttat gaagattggg aacaacttca
     5101 tccaaaatgg aacatgcaga cttcgctgat ttttgaacgt catccagcac caaatgaaaa
     5161 atatgaacgt cagtataaag aaggaaatga aaaaccttcg atcgttcact ttacaggaca
     5221 tgataaacct tggaatacgt tgaaagatca tccgtatacc aatttatact taaaaaaatt
     5281 agcacacagt actctaacga aagtaggcga gatcaatgaa taaaaaagaa atagcagtag
     5341 tcgcaagttg taacacaaaa ttcgtaccac atttagctgc attatttgtc tcagtattag
     5401 ataattgcaa cccgtctaaa tttgttcggt tctatgtgat tgacgatgat atcgattttg
     5461 aaagtaaaca gcttttacgc ttctcagtga aaaacgcacg aatgaactca gatgtggaat
     5521 tcttgaaaat caataaagaa ttctttacaa atgtggtaat cagcgatcgt attccagaaa
     5581 cagcttatta tcgtattgcg attccggaat tgttccgcgg cacagaagtt gaacgtatct
     5641 tatatatgga ttgcgacatg atcgctttac aagatatctc taaattatgg cgtcttgact
     5701 tcggtgattc aatcgtagca gctgttgaag acgctgggtt ccatcaacga ctggaaaaaa
     5761 tgaaaatttc agctaaatca atgcgttatt tcaactcagg tttgatgctg atcaatgtga
     5821 aaaaatggtt agatgaaaat attacgcaaa aagtattaga tttcatcgaa cataatccag
     5881 aaaaattacg attccatgac caagatgcat taaatgctat cttacatgac cgttggttac
     5941 cacttcatcc gcgttggaat gcacaaggct atatcatggc aaaagcaaaa aaacatccaa
     6001 cagcagcagg tgaacgtgaa tacgaagaaa ctcgcaacaa tccttacatt atccattttt
     6061 caggacatgt gaaaccgtgg agcaaggatt ttgaagggcc aacgaagaaa tattacgaaa
     6121 aatatgcagg gatgacggct ttccgttgtg tagctaaatt ccctaaatat ccaaaatatg
     6181 caaaagttca accaaaaaca gatgtagttg ttaaataata gaagaccaca actgaagagg
     6241 gggagtagga atggaaatta caatgtctaa aaatgcagta gagacgttaa ttgaaaaggt
     6301 tggggaaaat acaaaaatcg cactcgcgct tatcaatgat tccgatccat ttctaaggga
     6361 caaaggtgct tttgcaaaag gcagcttttt tcaaatcatt ccttttgttt cggaatttgg
     6421 agaatatgcg actaaaatcg agcatccatt attggacatc tatacatcta aattagagca
     6481 aaattatttc ggtaaacgat tgaacatgga cttcaacaaa cagcttgaca gcttttcatt
     6541 agaaaatgaa atcgcagtac tcgattataa tatcaaatta aagaactgct tcttcagcta
     6601 atagtttcga gaaagtccaa aaaggaggta tacattgaga tactactttg tggatgaaga
     6661 aaagaatgta atagaaacag atgaaaaaaa atataattgg ctcgtacttg atagtgcaaa
     6721 gcccgaagag attgagcaag caatcgaaga attcgagctt cctgatgata ttttcgtagg
     6781 aaccgaatat ccggaagaag tttctcggat ggagcgcctt tatgagacga aactagagca
     6841 tccattttct ttggtagtga ttaatctaga tcagtcagat aatcgtatcg aaaaaaaatt
     6901 aacgccaata tcttttgtac tttccgataa tctcttgatt acttgtatcg atagaaaaac
     6961 cgaatttgtg gatcggctgc tgacaaagca tggaaatcat ttaaactcgt ttgaaaagat
     7021 catcacgtat acattattag atatttacac ccattacgtg aaagaactaa gagagatgaa
     7081 aaagcgaatt gacgctttgg ataaagcagc tcgtaaaaca acggaaaatg aagaactgta
     7141 taaacaggca gatcttgaaa gagacatcgt atatatcgat cataccttaa gagatcaacg
     7201 ggaaacaatg gatcaattat ggaattctga aactttcatc aaacgtttag acgatgaaca
     7261 gctactctat gatgtccatt tgagacagcg acaaacagaa aaaatgatcg agatctatcg
     7321 agatttatta gagagtattg gtgatctatt caacgggatg atggacaata atctaaatca
     7381 tatcatgaaa tatctagatt cagctgcatt aatcatttcc gttccggcgt tgttcgcagg
     7441 gatttgggga atgaatacag gaggattacc gggtaaaagt tctgctctag gctttatact
     7501 cgtagtcttt ggctctttga tagcagcagt agttttaggt taccatttat accggaaaga
     7561 ttatacaaat taaagaatct atttaaaaca ggtatcaaac aaagaaattt gttttggcaa
     7621 tacaatttaa aaactaggag gaatacagca atgacagaac caaaattaat cgacccgcga
     7681 aacttgtacc atacggagaa atttcctaaa caagatcagg atacaccagc tttacagcag
     7741 aatatgattc ctgttcctga ttgtggagaa gaatcctatg aaggcaataa tcaactagaa
     7801 aaccgccgtg tactaatcac tggtggagat tcagggatcg gtcgtgcagc agcgattgca
     7861 tttgctagag aaggggcaga tatcgctctt caattcttcc caggagaaga aaaagatgca
     7921 gaggaagtag caaaatacgt gaaagatgca ggacgtaaga ttgtcttact accttttgat
     7981 cttcgtgacg aacaagcacc taaagaaatc atagataaag ccgtgagtga acttggcggg
     8041 ctagatacga tggtactaaa cgcaggacag caaatttctt gtcagtctat tgctgagtta
     8101 ccacttgagc aagtcaaaga cacatttatg ataaacatca tcgctatgtt tgctttagtg
     8161 aaagaagctg ttccgcatat cccagcagga ggagcaatcg taacaacaac ttctgttcaa
     8221 gcattcaatc caagcgaaca tttattagat tacgcagcaa caaaagcttc aatcgctaac
     8281 tttacgatcg gtttagcaaa acagcttgca cctaaaggaa tccgtgtaaa tggtgtagca
     8341 cctggtccaa tttggacacc attacaacta gacgaaggac aaccttctga ttcgatccct
     8401 gaatttggtc agcaaagttt actagaacgt gcaggtcagc caggagaatt agcaccagtt
     8461 tatgttttct tagcatcgaa taaagcaagt tatgttacag cccaaattta cggagtaact
     8521 ggtggagaag cgatcaactt ataagaagtt gatcgtttca cccctatgag gaggtgcgaa
     8581 aatgaataaa ggtgtaaaaa cgatcggagt gatcggaaca ttacttttgc tatctgtgct
     8641 tttgtttgcg atactattaa gtgcaaccta tccattgcct tttcagctag agaagtttcg
     8701 attcttttcc atcactaatt catacgtgca acaatatgta ttttggcttg ccgttgcatt
     8761 tgctattttg acaattatca cgttacttgt tttcctgttt tatccaaaaa caatcggaaa
     8821 ctttctactg aaacatggtg atggggagtt gacgttggat aaaaaagcaa ttgaaggaat
     8881 ggttcgttct cacttgcatg aagatgaatt catccattca ccaaaagtaa atgtcaaagc
     8941 aacgaaaaac aagatcgccg tcaatgtaaa aggggagttg aaacgaactt cagcactcat
     9001 tggtaaaaca ggaacattga tgaaagaaat cgaaaatgaa gtacaacaca tattgggaac
     9061 aaaagagcca gtgaaagtat cggtgaaata cacaggcttt gaagaaccag ctaaacgaag
     9121 caatgaccgc aaacgagtag aatagggggg gaccaaaaat gaaagaacta ttttcgacat
     9181 acaagctccc tatcatcttt ggggtacttg gattgatatt agccgtttta tggatcaccg
     9241 tgggcttttt caagacctta ttgatcttga tcatggcagc gatcggcgtc gctatcggtt
     9301 tttatctgaa acaaacgaaa atcttagatc actattttaa atcttaggag gaaacatcca
     9361 tgaataacaa taacaaaaat aataacaata aaatgaacaa ccaaaaacca gtgtctgcac
     9421 atccagaccc aacgacacca aaccaatcaa atggtgtgaa cgatgaaaag aacaaaacag
     9481 caccagtatc tgcacatcca gatccagtag tccctaacgt tcaacaagga gtagaagaga
     9541 agaaacatga tgcagaaaag catgcacctc atcatccagg aactccagaa tctaaagttc
     9601 cagaacaaca tgatgcaatc gatccttcta aacctgtgga agagcaaaaa catccttctg
     9661 accatgcgaa agcacaagaa aaacttagtt ctgaccacac aaacggacaa ggaaaacttg
     9721 gttctgatca tacaaataac caaggaaagc atgattctga acaggaagat tcaatgcgcg
     9781 gtgagctgaa ttatgaagat aaagttgtgc aaaaaatcat cggaatcgca attgaacaag
     9841 tagacggttt attatctgca aacggtggtt tcttctctaa tgtggcagga aaacttgtga
     9901 atacagataa tgtaacggct gggatcgaaa cagaagtcgg taaaaaacaa gtagcagttg
     9961 atatggatgt cattgtggaa tatggcaaag atatcgaaaa aatctttgaa gaaatgcaag
    10021 aagtaatcgg caaagaagta aaaaatatga cacatttaga agtgatcgaa gtcaacgcta
    10081 acgtagtgga catcaaaaca aaagaagaat ttgaaaaaga tcaagaaacg gtgcaagaca
    10141 aagtaactga cgcagcgaaa aaaaccggtg aatttgcttc gaatcaaaca gataaagtaa
    10201 aatcagcagc tggaagcggc gcacaaaaag taaaagaaaa tacagaacca cgggttcagt
    10261 aataaggaag taaaacatta ggaggaacga aacatgggat ttatttggtc acttatcgtc
    10321 ggaggaatta tcggagcaat tgcaggagca atcacgaata aaggttcttc gatggggatt
    10381 attgcaaatg tcgtagcagg tttagttgga tcagcacttg gtcaagcatt attaggttct
    10441 tggggaccaa gtattgcagg aatggcaatc gtgccatcat tgattggtgc catcatttta
    10501 gtactaatcg tatcattctt tgctcgaaaa ctgtaaaaag acttttaaaa agaggtcgtg
    10561 aaaaagctgt tcttcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
    10621 tcatttggtt gggcatatta tcgaagatgc aagcttttga acactgttta tacggaataa
    10681 gaggctgtga caagactttt gtcacagcct cttatttatg cgggcaaatt cccaattaga
    10741 tttttaaaag tttttcctta aatgtgtctt tattgataca gagaagcttc tttaataaaa
    10801 caatgcctcc ctaaattttc ttgagatagg aaaggtgaac atacaaaata atacgaccac
    10861 tttgaaaacc cagatgatcc acaaatggat cgtatgatac tgatgaagta aaaagcaatg
    10921 gatcagaaac tcaaagagat tgaaaaagac aaggaagaaa taatatctct tttttactct
    10981 tgtctgtttt agccaataat agctcgtaaa gtaatctaga caaacaaata gaagtaaaca
    11041 aagtttcgta agagcagcaa tcgtatcatg ttgctctgct agacgattga cgagcaggaa
    11101 aaatgttggt aatggaatat agatcacgag taatgaaaga aaaaagtaaa caataaatgg
    11161 catactattc ctcctaattg tgtgagttcg ccctcatttt aaaataacga tatttgtttg
    11221 tgaagctttt tcgtgtcgta acaaatgtta tctaatgtat ttttaaataa ataatcatta
    11281 ttatcaaaat aat
//
LOCUS       DAFLWZ010000082        11292 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000082 DAFLWZ010000000
VERSION     DAFLWZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.084"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            12..84
                     /locus_tag="L1V38_002368"
     tRNA            12..84
                     /locus_tag="L1V38_002368"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="L1V38_002369"
     tRNA            88..160
                     /locus_tag="L1V38_002369"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="L1V38_002370"
     tRNA            168..249
                     /locus_tag="L1V38_002370"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="L1V38_002371"
     tRNA            267..339
                     /locus_tag="L1V38_002371"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="L1V38_002372"
     tRNA            351..422
                     /locus_tag="L1V38_002372"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="L1V38_002373"
     tRNA            439..524
                     /locus_tag="L1V38_002373"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="L1V38_002374"
     tRNA            535..608
                     /locus_tag="L1V38_002374"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="L1V38_002375"
     tRNA            618..691
                     /locus_tag="L1V38_002375"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="L1V38_002376"
     tRNA            711..783
                     /locus_tag="L1V38_002376"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="L1V38_002377"
     tRNA            811..884
                     /locus_tag="L1V38_002377"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="L1V38_002378"
     tRNA            898..971
                     /locus_tag="L1V38_002378"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="L1V38_002379"
     tRNA            995..1084
                     /locus_tag="L1V38_002379"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="L1V38_002380"
     tRNA            1097..1170
                     /locus_tag="L1V38_002380"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="L1V38_002381"
     tRNA            1189..1264
                     /locus_tag="L1V38_002381"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="L1V38_002382"
     tRNA            1266..1336
                     /locus_tag="L1V38_002382"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="L1V38_002383"
     tRNA            1350..1423
                     /locus_tag="L1V38_002383"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="L1V38_002384"
     tRNA            1448..1535
                     /locus_tag="L1V38_002384"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="L1V38_002385"
     tRNA            1557..1628
                     /locus_tag="L1V38_002385"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="L1V38_002386"
     tRNA            1651..1740
                     /locus_tag="L1V38_002386"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="L1V38_002387"
     tRNA            1753..1826
                     /locus_tag="L1V38_002387"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="L1V38_002388"
     tRNA            1845..1917
                     /locus_tag="L1V38_002388"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="L1V38_002389"
     tRNA            1921..1993
                     /locus_tag="L1V38_002389"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="L1V38_002390"
     tRNA            1998..2068
                     /locus_tag="L1V38_002390"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="L1V38_002391"
     tRNA            2081..2154
                     /locus_tag="L1V38_002391"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="L1V38_002392"
     tRNA            2166..2237
                     /locus_tag="L1V38_002392"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="L1V38_002393"
     CDS             2503..3696
                     /locus_tag="L1V38_002393"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBN1316899.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="L1V38_002394"
     CDS             3826..5298
                     /locus_tag="L1V38_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316900.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="L1V38_002395"
     CDS             5381..6169
                     /locus_tag="L1V38_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBN1316901.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="L1V38_002396"
     CDS             complement(6236..6904)
                     /locus_tag="L1V38_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBN1316902.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="L1V38_002397"
     CDS             7019..8731
                     /locus_tag="L1V38_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316903.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="L1V38_002398"
     CDS             8734..10506
                     /locus_tag="L1V38_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1316904.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(10588..>11292)
                     /locus_tag="L1V38_002399"
     CDS             complement(10588..>11292)
                     /locus_tag="L1V38_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1316905.1"
                     /translation="MIFKFANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYLSKEE
                     VQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYELK
                     IKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQAYNQ
                     SLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTHTT
                     KNMQNQLVEKLGKIEI"
BASE COUNT         3250 a         2022 c         2554 g         3466 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag
    10621 ttgattttgc atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc
    10681 atgtcctaca cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat
    10741 gtgggaatgc cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac
    10801 tgctcttaaa gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa
    10861 aatgtattta tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat
    10921 ttctttagca ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt
    10981 tttaattttt aactcgtaat cataagtacc agaaaccgta attttattac catcataatc
    11041 agattcagtc aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt
    11101 aattaaagaa taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac
    11161 ttcttctttt gataaataac catctttttc tttttttatt tcttcgtttg tcttaggttt
    11221 tcttgctaaa gaaaccccat ttacgggatt atattttaat ccatatcgac ggttggcgaa
    11281 tttaaaaatc at
//
LOCUS       DAFLWZ010000083        11198 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000083 DAFLWZ010000000
VERSION     DAFLWZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.085"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(249..2057)
                     /gene="uidA"
                     /locus_tag="L1V38_002400"
     CDS             complement(249..2057)
                     /gene="uidA"
                     /locus_tag="L1V38_002400"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBN1316906.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(2080..3846)
                     /locus_tag="L1V38_002401"
     CDS             complement(2080..3846)
                     /locus_tag="L1V38_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBN1316907.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3859..4653)
                     /locus_tag="L1V38_002402"
     CDS             complement(3859..4653)
                     /locus_tag="L1V38_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1316908.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4663..6039)
                     /locus_tag="L1V38_002403"
     CDS             complement(4663..6039)
                     /locus_tag="L1V38_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1316909.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(6159..6806)
                     /locus_tag="L1V38_002404"
     CDS             complement(6159..6806)
                     /locus_tag="L1V38_002404"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBN1316910.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6890..8317)
                     /gene="uxaC"
                     /locus_tag="L1V38_002405"
     CDS             complement(6890..8317)
                     /gene="uxaC"
                     /locus_tag="L1V38_002405"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1316911.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8391..9470)
                     /gene="uxuA"
                     /locus_tag="L1V38_002406"
     CDS             complement(8391..9470)
                     /gene="uxuA"
                     /locus_tag="L1V38_002406"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1316912.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9473..11104)
                     /locus_tag="L1V38_002407"
     CDS             complement(9473..11104)
                     /locus_tag="L1V38_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1316913.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
BASE COUNT         3561 a         2281 c         1436 g         3920 t
ORIGIN      
        1 acttttttac agtaggcatc aaattggtgt tgtatagata tgtcattgta atgttgttgc
       61 atgataatat gctccttttt ccccctttcc actaatacaa caatcagaaa gccccttttt
      121 ttcgaaaaaa ctagaaaaaa aacataaaaa tatttatcat tctttaaaca gaaaatcttt
      181 ctataaaaaa caaaaaaaaa cgattaggct aggctaatcg ttttttgaac attcttaaaa
      241 aatccaaatt attttttata actgaaattg ggtattgatg accatcgttt ctgtagatag
      301 taagcaatca ttttaggttt tctatctcta gtaaagattc ctttcttatt tccttgcact
      361 cttaaaatcc cttgacttgt tgcaaaatct gcaaaattcc acacttgttc accaacaaaa
      421 ttttcacatg tatctattac ttcgtgattt gcttcgtaat aagccacttg atactcttct
      481 gtaaacattg ttggtactgt atcatgaaat ccagctactg tatctgctcc atattctgta
      541 aacattattg gcgtatcagg acatctttcc atccatccat ctagctcttt tttcaacaga
      601 tattttgcat gtgccagatc ccctcccgaa acataccaac cataataacg atttaaacat
      661 aaaacatcga caatatctcc taccttacaa acatctggcg ttgattttag ataagtaacg
      721 attgttacag gtcttttctg cggatcaagt tctttagtta attcaactaa aggttcaaaa
      781 tattctttag caccttcgga atccgaatct ggttcatttg caatagacca cattacaaca
      841 cttgggtggt tcttgtcgcg ttctatcaat tccttgatca ccgttttatg agaattttct
      901 gttcgtatct ctttccacgt attatgtttt tccacattat catctaataa agtggccatg
      961 aaatttaaat gtaaccctac tgcaggtact tcatcaataa ctacaatacc ttctcgatct
     1021 gctaatcgca taatttcttc tgagtaagga taatgtgatg ttctaaaaga attagcacct
     1081 atccatttca ttaaattaaa atctttaata tttacagcct cattcaaacc acgtccatta
     1141 acatacgaat cctcatgctt accaaatcct ttaaaataaa aaggtttatt attaatcaaa
     1201 aatttgccat tggtaacctg aacactgcga ataccaaatt cttctgtata ggtatcgatc
     1261 actttattat catcaattaa actaattttc atactatata aataagcgtc tagaggttcc
     1321 caaaaaattg gattcttaag ctgaatcatt cctttctttc cttcagcttc agctacaagt
     1381 tgagcctctt cgtcatatat cgctattaag atttttccgg tccattctgt atcgatattg
     1441 aattctacac ttgcatccaa atcagttatt cttgtattaa tagtaatatc acttatatag
     1501 tctttcggag ttgtatataa cttaacaggt ctatgaatac ctgcataatt gaagaaatca
     1561 aaattaacta agttttcctt ttttatatcc ccattttcct gtactgtttc cttcataatc
     1621 cccacaggta aagtactatc gtcaataata ttgtttacag caactgtaat tcgattattc
     1681 ccgtctttta caaaccgatt aatttcagac tcaaatggtg taaacccacc tttgtgttga
     1741 gtaataaact ttccattcaa aaaaactttt gcttcatgtg ttgcagatcc aaaacgaaga
     1801 actaatcttt cttctaataa tcttttagga agagtcactt ctttttcata ccacacccat
     1861 ccaacatgat ttctaatgtt ctctgtttca aataaatcat tataagaaga gggaactgaa
     1921 atcggataac tctctttttc atttattggt tctaaagcaa gttcttcctg taagtcatca
     1981 tttgtatcta atttaaatct ccagagaccg cttaagtcaa ttacttgcct cgtctctgtc
     2041 ataatgggat acaacatata aaccactcct atctaaatat taaataaatg tatcctttaa
     2101 accacaataa gcatctattg gacttactcc cttaaattca gaaagaccca ttagtttgtc
     2161 caccaatatt tctaaagttt cttgttttcc atcataagta ttaatataag tctttacttg
     2221 aggtacatca gccaaatgaa acggacactg tacagataca aaaattgttg gaatttcatg
     2281 aatgtaaaac ggtatatccg gagttccttt acttgctggc cagacaattc gttgaactgt
     2341 gcctggatta acattagcta tattaatgat caagtcatat tttttagtta aatttttaat
     2401 tggtctctta gcagcatata ttccagctat atttttaatt ttttcttctt gcgataatcc
     2461 tttcaattct tcttcaggtg aaatgtattt ttcaacttca aatccttttg ctgacaaaat
     2521 ctgtttcaat aaatcaatgg cttgaggtct atttccagca actacttcac caaacccacc
     2581 ttttacccca tgtacatcta ctagtaaaat ccttttatat ttttctggta caataggcca
     2641 aatatcttgt ttatctttaa ctaatgtaat tgcttggtca gccacctctt taaaaattga
     2701 tttattttca attaaaccaa ttttttccag agcttcttgc ttaggtaata aaatttgttc
     2761 ttttgctttt ttgtgtaatc ccaatttagc ttttaaccct aaaattcttt ttaaggcatc
     2821 taataaccga tcatcagtga taattccttt acgatagcct tccatcatat aattaaagtc
     2881 ttcatctgga tcattaaaaa atagaaatag atcacatcca gctgcaatag aagtgggcaa
     2941 taattctgat cgtttcattg ccccagtcat tcctaacata tgactagcat cagtaactac
     3001 taatccatta aatccgagtt ttcctctaag taagtcagtg attaattctt ttgataaagt
     3061 tgcaggaagt aaatcttcat ctttcagatc aggattaaaa tgttttgaat aagctggcat
     3121 atggatatga cctgccataa ttgaaggtaa tccagcttct attaagcctg agtatacttt
     3181 tccaaaagaa ttatcccatt cttccgtacc taaactatta atactaaaag atagatgctg
     3241 atctcgttcg tcaataccgt caccagggaa atgtttagct gcaggcaaaa ttccactctc
     3301 ctgaatacct ttcatataag ctaaactaag ttctaaaact ttatcagggt tttgtccaaa
     3361 agatcgacta gaaatgatag gatttctcca atttctatta atatctacaa taggagcaaa
     3421 actccagtta catccaatag ccgatgcttc aatcccagaa actctcccta attcataagc
     3481 atatttcgca tcatttgttg caccaatttt tacttctaca ccaacttcag taccatctgt
     3541 acaagctccg ttaccacctg cttccgtatt agcagcaatt aatagaggaa ttttactttc
     3601 tgtttgtaag atatagtttt gatcatatac ctcatcagca gttcctggat tatatcgtac
     3661 agctccaata tggtactgat tgaccatatt actcaagtaa tttttatcac gactagatcc
     3721 catattaaca aacaattgac ctattttttc ttccaaagtc atagaatcaa tcgtctcttc
     3781 aatccaagaa atagcatctt catctaaatt atatggtttt tttcgtaaat ctacttttat
     3841 agtcattttc tttctcctct acttattagt aagatttttc caaaaagtat ctatatattt
     3901 ttgttcaata tctacataat ctcccgataa acatttaaat aaaacatcag ttcttaagtt
     3961 ttcccatgat tctttttctt tattgaccaa aataggataa aagaaaactt tatttttatt
     4021 tgcagcttct agatcaccag gagaatcacc aatcattaat atcttatcca aatcacaacc
     4081 attttcaatt acacttcgaa taatatcttc tttttttcct ttatcttgac aacacagttc
     4141 atcaactaat gataataatt catgtctttc ccattcttct tgaacagctt ccttattagc
     4201 tgagcttaca ataattatct tcccatattt tttcagagct tttatagtat ctctagcact
     4261 taaaaagggt ttatctaatc cttttgcttg actaatctgt tgattgactt cttccgacca
     4321 ttttaaagct tttaataaat cctctgactg agaatattct atttccctct tcaaagatgg
     4381 attagacaat tcttttgtta gagataccca gtgctttaat cgattaatcg atgttacatc
     4441 atttttttct aatgttttaa ctaaacctaa aaatctgttt attccacgag tctctgaata
     4501 taaattaata ttattccaat cctgtaggaa tttttctcta tgatgaacat caaaaatctc
     4561 tgcagcaatt ggtccgaaaa agagattgtg tttataagtc atcgtatcca taacacagcc
     4621 atctgaatca atacaaaata tccaattatt catatttctc tcctatttat gtttttgttt
     4681 taaaagctcg caattttcta agactttatc tttagataat ggataaagga aaaataaaat
     4741 taatcctaca atcagaaaac aaattgatgg aattaatgtt gaagcgttat ataacttttc
     4801 taaaacatct cccgtttgta catttgctaa agagtcatag cctataatag aaagagtcca
     4861 acctccgacg cctccagcta gagcttgacc tatttttcta gcaaaagaat ataccgcata
     4921 tacggtccca tcttctcttt gatcagactt tacttcttga tcatcaataa catcagtaat
     4981 atttgcccaa ataacagtat taaacacacc caaacccata tagccaaccg aactaagaat
     5041 taagaataca tacatattac tagcttttat caaaaataag atcaaatata ctattgctga
     5101 aaagaacatt cctactgatg ccagttcttt ttttccatat tttttactta aaaacaaagt
     5161 taaaggcgaa acaactatta aaaccaaaat aggattgata aaattcatta aaactattcc
     5221 ctgtgcatca ttatagtaat caggaaatac ataattattc atactcataa ttaataattg
     5281 agcaaggagt aagaaaatag ccgcaccaat tatagaaagt aatgccctat ttttaactaa
     5341 cccttttaaa gattttaaca atgaaacttt gtattgagat tggtcaattc ttactcgttc
     5401 agtagttagt ttataacata ttaaataaca aataagtgca catatcgaaa atattcccgc
     5461 aacaattgta aaagttgatc caccacgaac tatttgagcg cctgaatcat ctcttgtata
     5521 aataaataat ggtgttaata caccaatgac caaacttgct aaagtagctc caacatttcg
     5581 gaatgtcgat agcattgttc tttcttctgt aatagaagta atagctgatg ccattgatcc
     5641 ataaggaata tttatagatg tgtaaaaaat actcccccat aatatatacg taacatacat
     5701 gtatactacc ttaacgctca tagaagctga aatcatagaa gtttgataca ttaaaaaact
     5761 tgctaaagcg actggaccac tcattcttaa aatccacggt ttaaacttac cctgcttagt
     5821 tgctttcgat ctatcaacaa tacgccccat agttacatca gtaactgcat cgataaatct
     5881 tgctactaaa aataatgttc caacggcagc tccgcttatc cccaatactt ttgtataaaa
     5941 gatcattaaa aaagaactag caaaaatgaa agtaaaatcg tttccaaaat ctccaaacat
     6001 atatcctatt ttgtctctta taccaaattt tctttccata caattctctc ccttctgttg
     6061 ttaagcgttt tcattctgat gaaagtacgt actatactct gaagcgtaaa gagtcagtat
     6121 ttatttttta catttcagag tattatttgt tttttctcct aataattctt tatctcataa
     6181 aacttatcta tatatttact agctactcga cttacttctt caaaatcacc tttttcaaca
     6241 gaagccaata aattcccacc tacaccaact gcaacaactc ctacttcaaa ccaatcttct
     6301 aagttctcta tacttactcc gccagtaggc attatattta cgtgtggtaa tggagcttga
     6361 taggctttta caatggatgg accaaaagca gaacctggga atagtttaat gatatctacg
     6421 ccagcagtaa gtgcctcctt tatctcagta attgtcatac aacctggtaa ataaggaatt
     6481 tgatataaat tacaaatctc agctgtttgt cgatcaaaag atggactaac gatatattct
     6541 gccccagcca taattgcgat acgagcagta aacgcatcta aaaccgtacc ggctccgatt
     6601 attacatctt tttgatcagc atatttttta gcaatttctt tgattatttc ttcagcatta
     6661 ggaactgtaa aagttagttc aatcccttta attccacccg caataattga atttattgct
     6721 ttaatggcct catccttatt tttcccacgt acaaccgcaa tgactccagc cgcttctaac
     6781 ttacttaaaa tttctacttt tttcatatct atctccttcc tttatggata catactttgt
     6841 ctagctgtac taacttacaa agaataaatt taagctttta tttcaagtat tattttctac
     6901 ttccgatttc aaaaaaatta aaataattat acgcattacg ataacaaata ttctccacta
     6961 tctgactaag atacatttca tcatctggaa ttcggcctgc tttaacccac tcgcttagta
     7021 attgacataa tactcgacga aaatactcat ggcgaggata gcttagaaaa cttcgagaat
     7081 cagtcaacat acctgtaaaa ttcgacaaca aactttgttg tgccatcgta gtcaactgtt
     7141 gacgcattcc ttcagctgta tcattgaacc accaagcaca tcccaattgg attttttgaa
     7201 tcataccccc ttggaagctt tgcattgctg ttgctagtgg aagccaatca gttggattta
     7261 atgaatataa aattgttttt ggtaagcacc cactcttttc agcggtatcg aacaatgcta
     7321 caacattttg tgtcaaacta gcttgatccc ccatcgaatc accaccgaca tctactccaa
     7381 tttgttcctt taatatactt gaattatttc ttaaagcatt taaatgcatt tgcatcgtcc
     7441 aaccatatct tgtatactca gacatcaaat gtaattgaat acctgtaaca aattgtgcaa
     7501 tttctgataa atggaaatcc gtttttcctg ctaaagcttt tattaacaga ttgtcgagta
     7561 ttttttcatc tgctatttca taaaaataag tattcaaacc gtgatctgct aatcgacagc
     7621 caatttgatg aaaatgatcc actcgttggc tcaatgcttg cttcaaccca ttaaagtctt
     7681 tgattggtat agccgctgtt tgactaagtt ttaaaatata gttcgaaaag cctgatgatt
     7741 tgatactcca gaccttatct ggacggaaag taggtaatac cttgaaagaa ttatcctgtt
     7801 tagaaagctc agtatgatac cacaagtcat ctgtaggatc atccgttgta cagatggctt
     7861 tcacatccat catctccaac aattctttcg ggcgatagga atccgtttga attttttcgt
     7921 tagcacgtcg ccaaatttct ggtgcattct tctcagaaat tgtcaaatca atatcaaagt
     7981 aacgttgtaa ttccaaatga gaccattcaa aaataggatt acctggcgcc ttctccactg
     8041 tttttacaaa agctaaaaat ttttcataat catcacctgg accactgatc aactcttctt
     8101 ctataccatt agctcgcatc aatcgccatt tataatgatc tccagctcct ttatcattta
     8161 accatacctg agtcaaattc ttgtattgct tattttctag caaatatgct gggtctaaat
     8221 gacaatgata gtcgataatt ggttggtgtt ttgcaaattt atgaaaaagt cttttagcta
     8281 tttcattctc taataaaaag ttcttatcta aaaacatatt taaacactcc tttccttccg
     8341 ttagttttta gaagagaaaa tttttcctct aaataaactc ccttatataa ttatttactc
     8401 gccccctttt caagcgcttc ccaaatacca tttaaataaa ctgcacctag agctcggtca
     8461 tataatccat aaccaggtct accggtttct ccccaaatca tccgaccatg atctggacga
     8521 atatagccat taaatccatt atcgtacatt gtttttaata tcttatacat atctagagaa
     8581 ccatattctg atttatgcgg cgcttcgtaa aaatcgagtc cattgtcact taaatatttg
     8641 atattacgaa catgtgcaaa aggaatccga tcccgttgac aaaattcaga tagaatttca
     8701 tagacatcat tatctggtcg ttctgcaata cttccagtac ataatgtaat accattagaa
     8761 ggagaatcca ctacattaca caaccaatct aaatcgtcac gatttttaac aatacgaggt
     8821 aatccgaaaa tggaatatgg tggatcatct gggtgaactg ccattttaat cccaacttct
     8881 tcacatgtcg ggataattgc tttgagaaaa tatgcaaagt tctctcgtaa tttctcttca
     8941 tcaacttctt tataggcttc taataattgc ttaatttgtg ataaccgatg aggttcccaa
     9001 cccggcaatt caaaattatt agtagaattt tctacttctc taataatttc ctccggatca
     9061 gtagggatat tttttgaaat ataggctaac gtagaagacc catcatctaa acgataatcc
     9121 aaatccgatt ttacccaatc aaatactggc ataaaattat aacagataac ctcaatccca
     9181 aattctgcca aattgcgaat cgtctgttta taattctcaa tgtattgatc tcgtgttggt
     9241 aaaccaattt tgatatcatc atgaacatta acactctcaa taactttcaa ggtaagtcca
     9301 ttggcttcga cttcatcttt taaagattta attcgttctc tcggccaaac ctctccggct
     9361 ggtatatcca ttaatgttcc aacaattcct ttcattgctg ggatctgacg aatttcttgt
     9421 agtgagattt tttcttcatt tgccccatac catctaaaag tcatttccat agttactttc
     9481 ctccaacttc tgttatatat ttattgattg ttttacgaac tgcttgagga cctactagca
     9541 tttcgcaaaa gattttttca gttttctttc ctaccccaac ttgatataaa tctaaaccaa
     9601 agatttcttt attttctaaa atttcctgta ccgcacaatg aatctttgaa ggatcttgtt
     9661 cacctaattt caatactgat aatttatcct gcaactctac caataacgga tcaggacttg
     9721 gcacaaaatt ttccccttga tcatcgactg ccagtaaata acgtaaccaa gcagcaatag
     9781 cgataggaat aaatgttaga ttttctgcat ttccgtcttt ttcgacatac tttttaattg
     9841 tttcaccata gcgaatcgct actttttgag aagtatctgt tgcaattcgt tgtggtgtat
     9901 ctggaatata gggattaggc aaacgtttat taattacttc atcaataaat tgttttggat
     9961 caataatgcc tggattttca actactggta aaccttctaa ataacctatt cctttgatta
    10021 aaccaaccaa atcatcatcc tgcatctctg ctgaaattga ttgatatcct agcagacaac
    10081 ctgttactgc caaagcagta tgaagtggat tcaagcttgt cgtaaccttc atgatgtctg
    10141 ctttatcaac cgtctctcta tctgtcataa tcacaccagc cttttccaat ttaggccggc
    10201 catttggaaa actatcttca ataactaaat aatgaactac ctcagtatta gtgaaagcag
    10261 caatattggt atgttttttt gtgtgaatga tatctaaatc ctcgagcccc atcatcaata
    10321 gatcttcctt tacattctct gaaggatttg gcgtaattcg atcaatcata ctccaaggaa
    10381 aagtcacttt ttctttatcc tttaaataag caataaattt ttcagaaaca tatccttctt
    10441 tttgccaagc ttctgcaatc gtaaaaatac tatcttgaaa acgttgacca ttctgtgaga
    10501 aattatcagt agaaaccatc gcaatcggca actctccagc attaaatctg ctatataaca
    10561 aggatgttac aatactcatc gtatgttgag gattgctagg tccagatttg atatcagctt
    10621 tgactaccga aaagaattgc cctttagaat cttttaaact gtaacctttt tcagtaatag
    10681 taaacgttgt aaactgtaat ttaggatctt caaaatattt aaccactctt tgatagtccg
    10741 ctatattctt cggattgcaa tataaactat cagccgttac tgccaaaagt ctttttttga
    10801 gttcaccatc tccactcata acaatttcca aaatgtcatt gttatagtca tgataagctt
    10861 tttccactac ttcttcatca aatgtttcac acacaactac tcctgtttct aattcatttt
    10921 gatctgctaa gcattgagca atttctgcat gaaatcctcg ataaagattt cctccaccaa
    10981 aatgaagcca tactggatgt tgctggcctt cttgcttaac ttctttgaca tcaaaacacg
    11041 gcagtagaat ctgcatttca ttgaattctt cgatagaatt ttgccaattt ttaatcgaaa
    11101 ccataattaa cctcctcaaa ctgatatgtt agttttgata cattttatat tttaaaaccc
    11161 attgtaaccg ttgtcaatat aaaaagggaa taaacttg
//
LOCUS       DAFLWZ010000084        11192 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000084 DAFLWZ010000000
VERSION     DAFLWZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.086"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            11..310
                     /locus_tag="L1V38_002408"
     CDS             11..310
                     /locus_tag="L1V38_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316914.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            383..1744
                     /locus_tag="L1V38_002409"
     CDS             383..1744
                     /locus_tag="L1V38_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1316915.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1766..2026
                     /locus_tag="L1V38_002410"
     CDS             1766..2026
                     /locus_tag="L1V38_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316916.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2040..2792
                     /locus_tag="L1V38_002411"
     CDS             2040..2792
                     /locus_tag="L1V38_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBN1316917.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2886..3491)
                     /locus_tag="L1V38_002412"
     CDS             complement(2886..3491)
                     /locus_tag="L1V38_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1316918.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKVLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3544..4518)
                     /locus_tag="L1V38_002413"
     CDS             complement(3544..4518)
                     /locus_tag="L1V38_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBN1316919.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4896..5615)
                     /locus_tag="L1V38_002414"
     CDS             complement(4896..5615)
                     /locus_tag="L1V38_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1316920.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5742..7013)
                     /gene="celB"
                     /locus_tag="L1V38_002415"
     CDS             complement(5742..7013)
                     /gene="celB"
                     /locus_tag="L1V38_002415"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1316921.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7166..8563
                     /locus_tag="L1V38_002416"
     CDS             7166..8563
                     /locus_tag="L1V38_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1316922.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8644..9084
                     /locus_tag="L1V38_002417"
     CDS             8644..9084
                     /locus_tag="L1V38_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1316923.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9232..9558
                     /locus_tag="L1V38_002418"
     CDS             9232..9558
                     /locus_tag="L1V38_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1316924.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9559..10308
                     /locus_tag="L1V38_002419"
     CDS             9559..10308
                     /locus_tag="L1V38_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316925.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10388..10843)
                     /locus_tag="L1V38_002420"
     CDS             complement(10388..10843)
                     /locus_tag="L1V38_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1316926.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT         3553 a         1957 c         2300 g         3382 t
ORIGIN      
        1 ggaagaaaaa atgaaaaatc ggttaattgt cgcatgtgga agtggagtag caacgagtca
       61 gacaatcgct agtaagatcc aaagtatgtt agaagatgac ggcatcgcat ttcctgtaga
      121 agcagttgat tacaaatcga ttcaaaatga gcttctaact gctggaatct atgtgtatgt
      181 cgcacaacct gatgaggaag tacttgaaca agcaaaagat ttgggtattg aagtatttcc
      241 aggaattcca tttttaactg gaatgggtgt agaacctatt tatgacagta tcaaagagtt
      301 agtacagtaa aggaggattg ttggataaaa aagttggttc atagttttat ttactatatt
      361 tagaaagaaa gaaggtttat ttatggaagt tttccaaacc attatcaatt atgttttgaa
      421 cttaggatca gccatttttg ttcccctgat tattttgata cttggattgt tggcagggat
      481 gaaattaaaa aaagcattca tgtctgcttt gactttaggg attgctttta gcggaatgtc
      541 tatggtcatt ggctatatgt ctaacgcagt aagtccagca tcagaagcat tggctaaaaa
      601 tacgggaatc agtttgcctg cacttgatct tgggtggaca ggtgcagcaa gcatcacatg
      661 gtcgtggagt tatgctttta tattttttgc agtaacgatt ggggtcaatt ttgtactgtt
      721 actttttaat tggacgaaga cgttaaatgt tgatatgtgg aatgtttggg ggaaagcttt
      781 aactgcttat ttagtttatt atgtttccgg tagtttggct gcaggctttc ttactgcaat
      841 ggtccaagtt atattggaat taaagcttgg tgatatgttt caaaaacata tacaagatct
      901 cacagggatt ccattagtaa cagtgactca ttttatgaca tctgccgctg tcttgttgct
      961 gcctttcaat atgatcatgg ataaaattcc tgctttaaat aaacgagcgg atacgaatgc
     1021 attgaagaag aaaattggga tcttctctga aaactctgta atgggattca ttattggatt
     1081 ggggcttggc tttgctgctg cgtatggcgt ttcaggttct cttaatctag cgatccaaac
     1141 agctacagca ttaagtttgt ttcctatgat ctctaaaatg ttcatgcaat ctttgtctcc
     1201 tctagcagac gctatgtcag aatttatgaa aaagcggttt aaggatcgtg aagtatatat
     1261 cggattggac tggccgatat tagctggtcg ttcagaaatt tgggttactg ctattttact
     1321 tgttcctgtg tttattggtt atgccattat tttgccagga aaccaagtat tgccattagc
     1381 agggattatc aactattcga ttgcggtcgg cggattactt ttaacaggag gaaacttggc
     1441 tcgtatgctg atcttgggaa tcatcactat gcctatttat ttgtacgggg ccacttacct
     1501 tgcgccaata ctcagtgatt tagcagaaaa aagcggagca gtcgagggaa tcaagaaagg
     1561 acagttgatc acatggtcat ccatagaagg gccggagttc agggttttat ttgcggaggc
     1621 atttaatagg aatattctcg ctattgtagg atgcgtgatt tttctaggac tgtttgttct
     1681 actttataaa tatatgataa aagcgaaagt accgagtgaa cgttatgctg aactacaaaa
     1741 atagcattga aatggtggga aagtaatgaa aagagaagag acagataaaa taaaatggac
     1801 agtcgctctt tgtggtacac ttctgctatt tctatatgga ctctttactc agaatatcat
     1861 catcaatcta ttggtcattt ttttcgcact agtgatctat aaatatggaa atcacgtttt
     1921 attcagagag tacgatgaaa aaagaaaacg gaaaatagaa gaatcaatga aaataaaaga
     1981 agctaccaaa gaaatattga gagaaaaaag ttttataaaa agataatgga ggggtcatta
     2041 tgtcagatgg acgtatgtta tttgagagag aacgacagga catggcacgt atcgtaagag
     2101 tgattttcga aaggaaaaac acaaatgtcg caggagggaa tttttccttt aaaaccactg
     2161 atgatcaagg gaaagactac atcatcatga cgccgaccat gatgtcagaa gcctatctag
     2221 gagagatttc tcctgcacag gttctagtag tagaaccaag aacgcgtaga atcgttgacg
     2281 gagtcggtca tttaactcgt gaaatcaata tgcatgaagc gatgtatgag actaatccag
     2341 ctatcaaagc tgtcctacat gctcatgcgc ctaatgcaat gttctgggcg actactgggt
     2401 tgcctatgcc taatttgaca gaagccacag ctaaagtaaa agagattcct gtcatggact
     2461 ttgagcctaa ttgctctgaa gaacttgctg aattgacaag cgactatgta aaaaaacagc
     2521 atctcgaatt accgcatatg ttgctgctca actctcatgg cgtattgatc aacacaggtg
     2581 gagaatcagg aatcgaagct atccataaag cactgcaaat ccttgataca gttgaatgga
     2641 atgcagaaat tgcctacaag cagacgattt ttcaagcatt agggattact gacggttttt
     2701 attcaaaagg tgagaaaatc gggggattgg aagagttgaa acataaaacg gctatttata
     2761 ataaatctgt tattgcagct ggtggagact aacctatctg acacaaaaaa ctacgacttt
     2821 cacaaaatct gatccagatc gatatctgct tcaggttgta ttatgtaagt cgtagttctt
     2881 ttcttttatt tagttaagag gtggtctgtc cattccctcg cttgcttgat ttcgtccatc
     2941 gtcaactgat gacctgttac agttagctga atagtcacat ttgcttggcg tgtttcgaat
     3001 tgatcggcca attctttaaa ggaagcaggg gaaacgattg gatcgttatc accataagaa
     3061 atccagacgg ttttatcctc taatgtggaa cggctttgat gaacacctag agacatcgga
     3121 tggaaaaaca acactttatt tagctcggtc tcacgctcca ataataaatg agcagcgatg
     3181 tttgcgccat ttgaatagcc gacaagcagc cagtcactta acggtatcag ttctttttcg
     3241 ctgatttctt tgattttttc atggagttta tctgtttctt tttccaaact gtccaggtcg
     3301 aattgattca atccattacg cttgaaaaaa cgattcatcc catcttcttg gaccgtgcca
     3361 cgaaaagaaa gcaatgtact gtttggtgca agaaagtgag cgatatccag taaagaatgt
     3421 tcatcgccac ctgtgccatg aagtaagatc aaatgcttgc cacttgttcc tttttcaaaa
     3481 atgtaggtca ttttgttccc tcttttctgt ttctatagat gcaaatgaag tagcatgaag
     3541 agattattca cgttttttat ttgcatcact tgtatcgaaa ggacggacat aagcttcaat
     3601 ggcttcacga cgttcttcta agaatggagg aagagatagt ttttctcctg ctgattctgc
     3661 tggttcatct tcaaggaatc caggaccatc agttgctaat tcaaacagta cgtgatgagc
     3721 ggctaggaag tactcagatt ggaaatagaa acgatcgacg aaaccagaat ttggcaattc
     3781 aatcttattg attacttgaa tccagtattc caatgcttct ttgtctgcta cacgcaatgc
     3841 taagtgatgg atatttccaa atccttcgat tgcttttggc aagtctgtcc gatgttcaat
     3901 aatgatgctt gcaccatttc ccccttcacc gatttcaaat aagtagaaat ctcctgaatg
     3961 gtctgtttct ttgaatccta agattttttc aagaatcaag cggatatgct ctaattgact
     4021 gacacggaca aagacaggtc caagtcctgt gatcgcaaac tctgtcggta cattgctgtt
     4081 tttccaagga atgccagctg ctacaccttg attgttttcg tcagagatca attgataata
     4141 ctgattatcg aaatcttcaa attcgatata ttttttgccg aaacgttcat tgattgctga
     4201 atgagtaacg tcatattttt caaaacgttc caaccaaaag tctaatgctg cgtcacttgg
     4261 cacacggaaa gaagcacgag agatcgtatc tgttcctttt tttccttttg gctgatttgg
     4321 aaaatcaaag aaagtcatat ctgttcctgg cgcaccagta tcgtctgtaa agtaaagatg
     4381 gtaagtttcg atgtcatctt ggttaactgt ttttttgatt aagcgcattc ctaaaatatc
     4441 tgtaaaaaag cggtagattt ttgtagcgct agatgtcatt gctgtgacgt ggtgaattcc
     4501 tctgatttgt gtatccatga taaatttcct cctgttaact tacaaaaagt aagtagttga
     4561 tttagacata gtatagaggg tgcatctcta ttttgcaatt aatttgtctt ctaaagtatc
     4621 aggaaggaat caagaatgga aaagaggagg gacggatcaa taaaataaaa agacttacga
     4681 ctagctgtat cgatttcaaa aaaactagct ttaaaaagct aactttagaa tcattacggg
     4741 tggtcataag tctttttatg ctgagttatt ttttcatttt tgagctaatg cttaggatag
     4801 aatagaatgt tgatttcacg atctcttctt gttacttgaa actgcttacc actgtcacga
     4861 tctcttggta aacggctttt tcacaacctc tttggttaag ttgaacgcac atccagcaca
     4921 gaatagttcc gaacatcaaa tcggtttcgg ctggaagaat attcaatcgg ctgtccatct
     4981 ttgagataga cgacttgctg aacttccagt acaggatcgt tttctgcaca gttcaaatat
     5041 tgctgatcat attcatcact tttatctgca gaaatagcac gataagcccc tgcaaaatgg
     5101 acattcaatt cttgatgaag atgatcatag atagaggcta acaaatgttc tttttttaaa
     5161 cccggcacaa gatggactgg cataaaggta tgctctaaaa catatggctc gccatctaag
     5221 atccttaacc ggtgaatatt gtagacaggt tgctcggcat cgatcatcaa tcgttcttgg
     5281 atatattgat tagggaattc aacatcaaaa tgaatgattt gactcttcaa agaacgatgt
     5341 ctgcgtttca tttggagact caaaccttca tactcgttag cgggcgatgt gtctttttgc
     5401 ataaatggat gattcaagat tttcgttcct gatcctcgct gcgaatagac aagtccttcc
     5461 attgctaaga tattgatggc ttttttgatt gtcatccggc tcgcaccaaa ttcttttacc
     5521 aagtcgactt gattaggcaa aaaactatcg agaggatact cttttgaacg gatacgttct
     5581 cttaaaatat ttgcgatttc ttcgtatttt ggcacgttat tcacctcttc tagagtataa
     5641 cgaaagatta tgcttccgac aactcgaagt agcatctgga acattgttta ttcgaaaaaa
     5701 gaggtcatga caagtttttg tcacaacccc ttaatgatct attaagcaat atctaaatct
     5761 ggttgtttat ctagtacttt caggaatggg taccagataa aggcaacgat gacaaagtcg
     5821 atgacttgca gcataccacc aagccatgaa tttgttgcta agacaccgct tgcaatgatt
     5881 ggcacagtcc atggaacaga gacgccagtt ggtgcaggga caagtccagc agccattacc
     5941 aaataattga acgtcgttac gattagaggt gccacaaccc aaggaataag gattgttgca
     6001 ttcaatacga tcggtagacc gaagatcgct ggttcattta cattgaaaat accaggtgct
     6061 aaagctaatc gtccaacatc acgatactgt ttctttttaa gaacaaaggc catcaataaa
     6121 acgacagcta aagtcattcc agagccacca ataccaacag tgaaggtttc catgaatggt
     6181 tttgtgatga tgtgtggtaa ttcttttcca tgttgataag cttctaagtt atcaagcatc
     6241 agtgtattcc aaatcgggtc cattacagag ttgacgatga tttgtccgtg aagtccgaag
     6301 aaccataaga attggacaaa gaacaaagca atcaatgttg caggtaaact acttcccaaa
     6361 ccagttaatg gtttttggat cacttcataa acgacgtcat gtaagttagc attgaaaata
     6421 ccagtcatca cagcattgat tactaagaaa atagttagtg tcactacagc agggatcaaa
     6481 gcggcaaatg attttgttac tgcaggcgga actccatcag gcattttgat ctgccagccg
     6541 cgtttcgtga ttctgcagta gatttctcca gccaagaaag cagcgatcat tccaatgaac
     6601 attccttttg cgccaagacg atcaagtgaa agcacaccag tcacatcttc accgccagcg
     6661 gttttcattg caaaaggcgt aagaatcaag aagctggcaa aagacacggc accaccgaaa
     6721 ataccttcaa cgtcataaga ttttgataaa taatagccga taccaaaagt aacaaaaacc
     6781 gacatgatgc tcattgttgc attttgccca ttaccgaata aattcgataa agttcccttt
     6841 gttgcgtcac tgaaaaaagg caagttattg ataacgacaa cgatcgaacc gaacatcgtt
     6901 aaagggaagg aaagcatgaa agcatcccgc agcactgtaa ggtaacgatt ttgccctaat
     6961 aaattagcta agggcatgat tttctcagaa agcttgtcca taaaaccgtt catttttatt
     7021 cacctcaaat ttatttgcaa tcgattacat acaaagtata acgccaaaaa ttttaaatgt
     7081 ctagtcattt tcataaaaag tattgattta ttttttaggg ttcgttatga ttacggtatc
     7141 aagaaaaaag agaggaagta aaaaaatgaa aacctacaca ttcccagaaa atttttggtg
     7201 gggttctgct gctagcggac cgcaaacaga aggaagagta agtgatgatg gtaaaggaga
     7261 aaatatttgg gatcattggt atgaattaga gcctgaaaaa ttcttcgatc aagtaggacc
     7321 tgaaaaaact tcgcaagttt acacaaaata caaagaagat gttcagttaa tgaaagaaac
     7381 tggccataac acatttcgta catctatcca atggagtcat ttgattccag aagggacagg
     7441 tgaaatcaat caaaaagctg tttcttttta tcgagattat tttactgaat tgctggataa
     7501 tggtattgaa ccttttgtga acctttacca tttcgatatg ccactaccac tgcaagaaaa
     7561 aggcggatgg ttatcaagag aaacggtcga cgcttatgtt tcttatgcag cagcgtgctt
     7621 tgaactgttt ggagatctgg tcaaaaaatg gtttactcat aatgaaccaa tcgtacctgt
     7681 agaaggaggc tacttgtatc aattccacta tccaaatcat atcaatatga aagaagcggt
     7741 ccaagtaggc tatcatgaga atctagcaag cgcaaaggta atcaaagcct accatgaagg
     7801 cggacatgat ggtgagatcg gaatcatctt gaatctgaca ccaagctatc cgagagatga
     7861 aacgaaccca gaagatgtaa aagcggcgaa gatcgctgac gcattcttca accgatcatt
     7921 ccttgaccct gcagtgaaag gagagtttcc acaagagttg atcgaaattg tcaaagaatt
     7981 ggctataatg ccagagatcc atgaaggaga cctagaactc atccgtgaaa acacgattga
     8041 cctgctagga atcaattact atcagcctcg tcgaatcaaa gcaaaagaaa ctccaatcaa
     8101 tcacgaacat agccccatgc cagatgatta ttttgataat tacgacatgc ccaataaaaa
     8161 aatgaatcca tatcgtggat gggaaattta cgaaaaagga atctatgata ttttaacgaa
     8221 tacaagagaa aactatggta atatcaaatg ctatatttct gaaaatggga tgggggtcga
     8281 aggagaagaa cgatttgtta acagcgaagg aattattgaa gatgattacc ggatcgagtt
     8341 tgttacggat catttgaaat acgtccatca agcaatccaa gaaggaacca attgtgtggg
     8401 ttaccacatg tggacatgta tggacaactg gtcttggaca aatgcttata agaatcgcta
     8461 tggctttatc gctgttgatt tggcacaaga cggtaaacgg acgatcaaaa aatcaggtcg
     8521 ctggtttaaa acggtctctg aaaaaaacgg atttgatgcc tgatattttt tgataaaacg
     8581 ttcacaaaat gtttgttcta acactgtaat cgtgctacac taacagtgaa ggaggcgttt
     8641 acaatggtag atacttatcg taatatttta gtagcaattg atggttctga aaaggcagaa
     8701 aaagcatttc ttgaggcaat cacgattgcc aaacgaaatc aggcaacgtt gcacatcctg
     8761 tatgtcaatg aagtaacagg caattacttt ggtgattttg catttgttac aacaagcctt
     8821 caggaagaat tggatgaggt tgcggaaaac cagatgaaag aacatcgaaa cttggcaatt
     8881 gaaaaaggcc tgacagatat cgagacatat gttctttacg gttatccaaa gacactgatt
     8941 gctaatttcc atgaatcgaa agaaccaatc gatctgattg tcatgggggc gacaggtctg
     9001 aatgcggtag aacgtgcact agtaggttcc actacttcct atgtagtcaa ccacgcatca
     9061 tgtaacgtca tggttgtaaa ataaataaat taagggaaca gaaagcaaaa aagcataacg
     9121 cttcttttgc tttctgttcc ttttattttt ttgtaaaaaa ttactttacc tgatgaagta
     9181 atcatgctat tctaattaca acgacagatg gagtaatatg gaggaaagaa aatgatttca
     9241 agtgatggaa tacgcggata caatgatgcg attattttat cgatccttaa caaaaacgat
     9301 tcttatggat atgaaatttc taaaacgatt cgtgagagga caaatgattc ctatgtgatc
     9361 aaagagacaa cactttactc cgtttttgcc cgtttagaaa agaatcaact gattgtttcg
     9421 tatcctggag aagtgactca tggaaaaaag cggacatatt ataaaatcac tgaaataggg
     9481 cgtaatcttt tagaagaaaa aaagcaagag tggctgacga cgaaagacgt agtcgatcaa
     9541 tttttggagg gaaattaaat ggatacaatc cgtaattatt tagacagtct ttttatcgga
     9601 gtacctcaaa gtaccgagat agataagctg aaaactgatt tgttggcaaa tatggaagac
     9661 cattatcatg aattgatggg agaaggaaaa aatgaacagg aggccatcgg tacagtaatt
     9721 tcgacatttg gttcaatcga tgaattatta gaagaactag atgtcgaaaa aaaacatcaa
     9781 gctgacgaga cggaaacaaa cacagcttct atttatttaa gcgaagcaga aaactactgg
     9841 aaagaataca gagcggcaag tctccaagtg gcatcaggtg ttctattcat tagcttatct
     9901 tttgcaagtt ttcttttctt ttgttcagca ggatatgtgt tcatgggtat ttcttgtctg
     9961 attttcggta tagcattagc tgtcggtttt tttattgctt ctggtatgaa aatcacacgt
    10021 ttaaatcact ttttgcacca tcggaaaata cctgaaaaag tattagcaga agcaaaagaa
    10081 aaagaagaag agtatcagcg aagttttggc ttctcactga ttgcaggaat tggattatgt
    10141 attttttcac ttttcccact tttggcttct ttaatgtggt atatggatgg tagtatcggt
    10201 gcctctatat tttttgttac ggtaggaacg ggtgtcttct tgatcattta tggcagtcta
    10261 gtccgtcatt cttatcgtca attcactcaa agcgcttatt actggtgaat gtattcagat
    10321 ttgtaaaaat attctattta tccggcgtag aaaaaaagac tgtgacacgc ttttgtcaca
    10381 gtctttttta tatataataa tttaaaaatt catcatctaa atccgtagaa ttttctagat
    10441 tgcttaccca tgtaaaatcg ttatagacag atttcagttg acttctgcgc cattgtacag
    10501 ggataaaaag acgcatgcta tcttcattga atccgactaa taatttcttt ccgtcagtaa
    10561 tgatgggacg ttgtaacaaa gtaaaatgcg agacgatcag atcgacaagc tctgaggtcg
    10621 tacattggtc gatttggtct ttcaaatttt tataatcaat cgagcgttta gctaatagat
    10681 cgtcaaatcc gttttctgtt aatgacaata aataaaatat ctctttcctt gttaaaggct
    10741 gtttaggtgt gaaaattcgt tctctgtaag gcatttgatg gtctttcagc cagtttgcca
    10801 tcagatggta actatgtgtg cgagaagaat agatcgtaag cataaaaaaa ctccttaaat
    10861 agtccattaa tttgttagat ctgttgagat aaataatagg taaggagctg tgcataagca
    10921 ttgatcaaaa caacccaaac atcattagaa ataactttct aaagtcttaa acttgcgacg
    10981 agaagcaact agactaatag aaaaaatgtc ttagccattt ggcttcctgt ttgttttttt
    11041 gcttatgctg cagctcctcg ggaaagggtt ctaacaattt gaagaaggtt gatgattgat
    11101 ctagtttaaa ttgtgtgaaa tttgaaatct ggtgttttta ctagatgaat cacctaacaa
    11161 ctatgattat aacttataga acttctgttt tg
//
LOCUS       DAFLWZ010000085        10786 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000085 DAFLWZ010000000
VERSION     DAFLWZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.087"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            5..2377
                     /locus_tag="L1V38_002421"
     CDS             5..2377
                     /locus_tag="L1V38_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316927.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="L1V38_002422"
     CDS             2438..3898
                     /locus_tag="L1V38_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBN1316928.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="L1V38_002423"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="L1V38_002423"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1316929.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="L1V38_002424"
     CDS             6129..6278
                     /locus_tag="L1V38_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316930.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="L1V38_002425"
     CDS             6353..6946
                     /locus_tag="L1V38_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBN1316931.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="L1V38_002426"
     CDS             6959..7858
                     /locus_tag="L1V38_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBN1316932.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="L1V38_002427"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="L1V38_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1316933.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="L1V38_002428"
     CDS             8724..8984
                     /locus_tag="L1V38_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316934.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="L1V38_002429"
     CDS             9429..9635
                     /locus_tag="L1V38_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBN1316935.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9683..9886
                     /locus_tag="L1V38_002430"
     CDS             9683..9886
                     /locus_tag="L1V38_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316936.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="L1V38_002431"
     CDS             9902..10339
                     /locus_tag="L1V38_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316937.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..>10786
                     /locus_tag="L1V38_002432"
     CDS             10332..>10786
                     /locus_tag="L1V38_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316938.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDY"
BASE COUNT         4078 a         1800 c         2261 g         2647 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttatta
//
LOCUS       DAFLWZ010000086        10477 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000086 DAFLWZ010000000
VERSION     DAFLWZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.088"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            34..657
                     /locus_tag="L1V38_002433"
     CDS             34..657
                     /locus_tag="L1V38_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316939.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="L1V38_002434"
     CDS             1107..2156
                     /locus_tag="L1V38_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1316940.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="L1V38_002435"
     CDS             2153..3034
                     /locus_tag="L1V38_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1316941.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="L1V38_002436"
     CDS             3037..3807
                     /locus_tag="L1V38_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1316942.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="L1V38_002437"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="L1V38_002437"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBN1316943.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="L1V38_002438"
     CDS             5118..6281
                     /locus_tag="L1V38_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1316944.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="L1V38_002439"
     CDS             6398..6808
                     /locus_tag="L1V38_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1316945.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="L1V38_002440"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="L1V38_002440"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1316946.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="L1V38_002441"
     CDS             9381..9665
                     /locus_tag="L1V38_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316947.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9825..10061
                     /locus_tag="L1V38_002442"
     CDS             9825..10061
                     /locus_tag="L1V38_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1316948.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10375
                     /locus_tag="L1V38_002443"
                     /pseudo
     CDS             10058..10375
                     /locus_tag="L1V38_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
BASE COUNT         3659 a         1746 c         2228 g         2844 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcatatagtt
    10381 ttttcataaa aatatggaaa atatggatta attttgaaat aattgattta aaaggaatac
    10441 aaaagagtga atagtaggaa atagtggttt agaacta
//
LOCUS       DAFLWZ010000087        10435 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000087 DAFLWZ010000000
VERSION     DAFLWZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.089"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(12..1647)
                     /locus_tag="L1V38_002444"
                     /pseudo
     CDS             complement(12..1647)
                     /locus_tag="L1V38_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2086..2955)
                     /locus_tag="L1V38_002445"
     CDS             complement(2086..2955)
                     /locus_tag="L1V38_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1316949.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(2975..4096)
                     /locus_tag="L1V38_002446"
     CDS             complement(2975..4096)
                     /locus_tag="L1V38_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1316950.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(4098..4493)
                     /locus_tag="L1V38_002447"
     CDS             complement(4098..4493)
                     /locus_tag="L1V38_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1316951.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(4512..5318)
                     /locus_tag="L1V38_002448"
     CDS             complement(4512..5318)
                     /locus_tag="L1V38_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1316952.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(5311..6099)
                     /locus_tag="L1V38_002449"
     CDS             complement(5311..6099)
                     /locus_tag="L1V38_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1316953.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(6113..6589)
                     /locus_tag="L1V38_002450"
     CDS             complement(6113..6589)
                     /locus_tag="L1V38_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1316954.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(6661..9318)
                     /locus_tag="L1V38_002451"
     CDS             complement(6661..9318)
                     /locus_tag="L1V38_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1316955.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(9337..9741)
                     /locus_tag="L1V38_002452"
     CDS             complement(9337..9741)
                     /locus_tag="L1V38_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBN1316956.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(9973..10230)
                     /locus_tag="L1V38_002453"
     CDS             complement(9973..10230)
                     /locus_tag="L1V38_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBN1316957.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
BASE COUNT         3339 a         2081 c         1506 g         3509 t
ORIGIN      
        1 aaaaaatgta atcagatcat tatttttata tgttgtaact tcctgataag aaaactaatt
       61 aaaagaaaga ggtaactaca taaactaatt aaaaaagcta acttcatagt tggaggataa
      121 atggaagaaa cttcaatgat tgtttctcct tgtgttcctt caatcgacac tagtcctatt
      181 atcaatctct cttttttgtc catttacttt tgcgactgtt ccccaataat caaatacagg
      241 aagcgttatt ttttgtcctt tagattcatg tactgtatag actattttcg aatccatcac
      301 ttgataaggc atagtatgcc attccttgcc aattcttact tcatgattct gcaaatgttc
      361 tttgtattgt aatgcttccg tgggtgcata gtcataaagt cctccgggaa ggagtgtcgt
      421 gtaacgaata agattttctt gattcattac caagtgatct ctctgagtga caactttatg
      481 ttcatagttt gcttttgttg cagcagatac agccaacagt aataaaacaa ttgccgttat
      541 attaactact tttctttgct tagctgatgt gctcttcatg aaaacgaacg ataaaatcaa
      601 cgagccaaac agtacttgaa agcctaagat tcgccaagga aattgaatca tttgaatggg
      661 tgtattttgt aataaagacc atggaaaaaa tttggtggat aagagccaag agactaccgc
      721 actaaggtaa atcacttttt ctttgcgatt aaatccttta aaaaagaaga gtggacagat
      781 caaagaaata ataccaatga ttcctaccgt aaaggttgtc aggtcattat tcatcgcacc
      841 aatcaaacta tccgagacat ttaatgcttg gtgttgtaag gtcgttttat ctggctcatt
      901 aatcgattga accatgattt gtcggaacat cggataccaa aagtatgctg ttaaaagaat
      961 cgtcattcct actgcctttg acaactccac aatcaaccgg atgctttctt tttttcttgt
     1021 ttcacttact acaaagccgc ctaagactag taagccaacg gctattacac tcataaaagt
     1081 ggaaagaaca tgtgtataaa tgagtaagct catactgact gctaatggaa ttgcacatgg
     1141 ctttttctca taaatcagtg cgtaagcata atacataact atcggtataa ccgtaagtgc
     1201 aatcgcttca gcaatagcag aacgatgata aatatcaatc gtacggtacc cataaaatgt
     1261 atataaacag ctaaatataa aagccgcatc gattcttttt aaaaatttta gtccataatg
     1321 aaacatcagc atgatagtac aaacattcaa tagccaaaca tataagatat aactaacgat
     1381 taaattatta cttatccaat aaaaaatgac tgccggaaaa aaggtcaagt agggataaaa
     1441 ataattcact ccgctcccat aatgattaaa cgtcgtaaaa ttgattggac cagaaaaaat
     1501 tgaagataac cctttgactc tagcaaaatg gaaggcaata tcccccgatg tagaaatagt
     1561 atgaacattt ctaaaataat tgattgaata aagtccagca ataattgcta ggagaatgga
     1621 caatattatt tttttcttta cttgcattac ttaattatat actcctttca tggattgctt
     1681 tatctagtat aacttaaatt ttaaataaat cgttatttat ttttactctc acttaaaaaa
     1741 gcactaaaat tataagagag ggaggtaatg gtctgaacac caagaattgt tccaacatcg
     1801 aattgcttaa ctaatgagtt caaagcttaa ttatgtggct cttatattta ccgagcgtgg
     1861 attgcgatct ctttagcgaa acaaacatct ttcataaaaa aaacagccat atccgctttc
     1921 ttggatatga ctatttacta ctactttact atctttcatt cttcttgtct cacttatgat
     1981 aaggcgctgg gtatcatgag tgaatgatat tgctgaatac aaatagtccg accacattaa
     2041 gttgatcgga cttcataagc attttattga ctaatacttt tttgcttaag aattgattct
     2101 aacatctttt gctaaagtta agcatcctat agttcctgca ttatctgcta acttaggtgt
     2161 gacaatgtat tcttcgatat ttggcgtatc gacatagccg ttaattagtt ctaaaaaacg
     2221 tctttgtact ttctttttca gatgttcttg ttgcatgaca ccaccaccaa aaattataat
     2281 atctggtgaa agcatcaggg tcgtattaca ggcacattgt gcaatataat ccgcctcgat
     2341 ttcccagaac ggatcttcta tagaaagatc ttgtcccttg gttcccgtac gcatctcgat
     2401 agcgggtcca gatgccaacc cttcgagaca atcatgatga aaaggacaag taccagagaa
     2461 agtatctcct gaatgtctct taactaacgt atgccccatt tctggatggc taaacccttc
     2521 aacaaaaatc ccatcttgta tagctcctcc accaattcca gttccaacag tgtaataaac
     2581 aacactggat aaaccttttc catgacctga aacatactcc ccgtaacaag cagcattcac
     2641 atcggttgtc caggcaattg gaatttcgaa atgcttattc aacgttccaa caaaatcaaa
     2701 atttttccag gcagtttttg gagtagaggt gatatgtcca taggtctttg attcacgatg
     2761 gatatcaatc ggtccaaatg accctactcc aatgctttct aattgttctt tatagtgatt
     2821 aaagaaatca attaccaaac tcattgtttc attcggtgta gttgtaggaa aactcactct
     2881 ttctaaaacc tttaaatcat cattgccaat ggcacaaaca aatttagtcc cacctgcttc
     2941 tattgagcca tacatttctt actccaccgt ccttttatct aggaattcgt tcttccctgt
     3001 ctaatagttt ttcgaaaaac tcatgtggtt ccttttggta ccaataggca acagaagaaa
     3061 tatcgtcttg acgctcataa agcttgatgt catcatttcc tagggtttgg aaagtaacac
     3121 gtaaattttc tttgaaacta atggggtcgg gtaaatgcca gcggtacaac ccatgcatcg
     3181 gtaaagcatc atcgccaaaa ccatgaactg gatttggatt aggttttcca gcactaaaat
     3241 aatcccgggt gtgatctctt ttagattgaa aaggatagcc cataaatagc gtattaaaat
     3301 tttgagcata tgccctttct ccaaagttct ttttatggaa agcccaagcg ccgccaaaat
     3361 aatcttctgc tcctgtagat gttattgtag ggaaatcttc atctccatct atataaaact
     3421 taaattctcc ttccccccac cagtatcttt ccaatgcgca caaagcaaag taggttccta
     3481 cataataccc agtgcctttg attccatcaa taagggtgta atcttttcct tttgtcgtga
     3541 tgggttcacg gttccattta gcatgaaaat acatcgcatc atccggtact tcagtcaatg
     3601 cataattaaa tgtataaaaa atgtgcttaa taaactcagg atgttcattc gttaaagtaa
     3661 tcttagcttt ttttcgaaat ggcatctcaa aatagcaatt catccctgat gttggattca
     3721 ctacgattgg taaggaattc acttcgcatc ttgtcccaaa cccattacaa aaaaaatctc
     3781 ctaatggact ttctacagaa ggagtggatt catcatccca ataaatacgc aaaattaaat
     3841 cacgtaagac gaaactccca gcgattgttt tgtctgtcac tgtcatccaa aaatgacgta
     3901 aaattccagg gccttccatt tctgctaaag taattgtctc tccagcattt atcggaacag
     3961 aaggtgaccc ttttctccca attcctagat gactcgctgt cattgccgct ttcccttttt
     4021 caccattttt attttctggt gaaatagttc tactttcctc tcccttgtgg agccatatat
     4081 tatttaaaca attcatttta ttcgtcctct atcctttctt cacttttttg attattcata
     4141 tagatgattt gttgttgtgc ctccgcaata attgctccaa tatctaaatt atcatttcct
     4201 aactgcaaag cgattgacat tgccaaggga agattcattc ctgcaattac gtgcactctg
     4261 tcagaaatat aggtaaaaaa cttttgattt acacttcctc cagccatgtc agttaaaaca
     4321 attatttcgt ctgtagtatc cactaactct ttaatttgtt catctatatc atcaatttct
     4381 tcgacatatg cacataagct actaatttga ttatgcatac ctgttaaaaa ctctagtgtc
     4441 tctttaaaac cctcagctag tattgaatgg ctagcaatga tcaatcttct cataattcaa
     4501 atccttttcc tttacgctaa tattccaaat gcagccataa ccatcgcaaa aacaataacg
     4561 agtagaatca aaatggtcat actgattttt ttcttactga gtagataata tgctgcagca
     4621 gtaataatta ctggaattaa tgttggtaaa attttgtcca acattggttg gattttcata
     4681 ctaacttcac caaaagtgaa tttaagtggc gttgaaacac tgataactga agcaattaat
     4741 gatccaacta ctgttagccc caatactgaa gcagcttcag ttaaataatt aatcttttca
     4801 ccgtattcag taacaatctt cattccctgc ttataaccaa attcaaagcc tctcattcgg
     4861 aaaaagaaga ttaccatgat taaaatgaac cataaaaaga ttcctacagg attattttct
     4921 aaagccatat aagccgcaat tgatcccatg atggttggga tcatcgtcat caaaagagag
     4981 tccccaatac cagcaattgg acccatcgta ccaactttaa agtcattaat cgcatctttt
     5041 gcttctaatc cttgcttttc ctccattgca acacaagcac ctaaaataat ggctgccagc
     5101 caaggctgtg tattgtaata ctgaaagtga ttatttaaag cttcgatgta ttcatcatca
     5161 tctttgtata attttcttaa aataggtgac aatgcgtaag tcacagatgc accttgctgt
     5221 gtttgataat taaaggtaca aactgacatc aaccaacgat agttcgcttt cctaagatcc
     5281 tttttcgtta cttgatattt ttcgctcatt ttattcatcc tccccaataa acccaacatc
     5341 agaagctccc gcagaagcag tgatttgtgc atctttttca gctctatgat acacattaaa
     5401 tgctaaagcg aatcctatga tcgccgctcc aataataggt accttcaaaa aagcggctaa
     5461 gaaaaatcca acaagtaaat aactaatgta tcgacctgta ggcataaagc gtaacaacat
     5521 cgcaatacca acagcaggca acatttttcc ggctaatgtt agcccatcca taaaccaatt
     5581 aggtaaaaca tccaaaacgt aattaacagc agactgtcct aaagtaacgg caataaatac
     5641 tggaattgct gcagataaac caaagaaaat tggccccaac cacaaaacac tattcatttt
     5701 cttaaattct cgtttattcg catattcctg tgatttgcga acaacaaaac catttaagat
     5761 tttgacaatt acatctagtt gcacccctaa catacctaca ggtagtccta ttgctaatcc
     5821 ggcttctact ccaagctggc taccaaatgc cgttgcaata attgcgcacg ttccatagtc
     5881 cggtacagat gagccaccaa aaccggcaac tcctaatgac atcaattgaa ctgtaccgcc
     5941 aactatcaaa cctgttttta tatcacccat caaaattcct gtgaataatc cccaaaaaac
     6001 tgcgtaattt acaaagatca tcggaatccc ataataatca acatgtttaa taaatgctaa
     6061 tatagtcagc ataataattt gaaaaatagt aaaatgcatt atccttactc ctttatccta
     6121 attttgattg aatttcctgt gccttatccg ccggaacaaa ttgtgtaaca atttctacac
     6181 cagaatccaa caatttttta tacgtgctga tattttcatc tgatgcatag gctctagaag
     6241 atagctgtaa tgcattatct ttaacaacag taccgccaac aattagtcgg tcaattctaa
     6301 taccgttatc tactaaatga aggattgttt ccggctcttt cacgatgaca aatacttttt
     6361 cctgatcgta tttccccttt ttaaaattcg caatcgctgt ttcttcagtg ataattgata
     6421 cagccattcc agcaggtcta gctaaacgca tacttgattt ttggatgtcg ttatttgcga
     6481 cagaatcatc gatcaccatc actctgtttg ctttagacat tggtgcccat tgcgtgacaa
     6541 taatcccatg caataaacgg ttatcaactc tcgacataac aatactcata aatacttcct
     6601 cctttatctt tcattttctt acaagcaatt accatgccaa aacaaaaaga acttgataaa
     6661 tcaagctctt tttacataat cataaacgta tttaacctca tgaatcggga tgtcgacact
     6721 ataataatgt tcaacgacac tgaaagattg cttaaaatgt gtctgaaatt tttgaaattc
     6781 ctcactcgtt tcattgaaat aaatttcatc ttccaaagta ttttgtttta ctaatcgttc
     6841 aattaagcaa ctaatgtgaa catataatcc gaaacacgta ttattatcaa atgaaattcc
     6901 tagatcattt tgtaagatgt atatagcatc tgaaacccgt tctaataatt tagtcggatt
     6961 taatatggtc aattgctcca ttaaattcgt tagactaaaa ttcttcagaa tattattgtt
     7021 caaaactttc agttcattat cattaaagtg tctattcaat tgattggaga atttacttat
     7081 attcattcct aaaatcatat cttcaattga aaagaattct acatcttcta gatgtggatt
     7141 tagtgttcca acaataaaaa gaatattgtt ctctttacga agctccgata aatagttttc
     7201 attcactaaa gagtaatagt cacacgtttc tatgacaaga tcagtatccc ttggaaagct
     7261 atcttcaagt atccttttta atttaaacga agttcctaat ccgcttgcac aagaacagac
     7321 aatcatatcc ttcttaatat ttgatgattc ataaatataa tccacatttt gattttcttt
     7381 tacttgttca agaatctgtt taagcggtaa atctaataat atctgatttg caacatcaat
     7441 agccattctt gttgaaacat tgtttagtag tccgaatttt ttttgagcgt ctagttccaa
     7501 atttagataa attttctcca gtgaacccat atcaacaagt aaaataattt cttcatatcc
     7561 ggtacactct tgtaagtatc tattaatttt gtctgcaatc tcactacttg aagtcattag
     7621 tggcatatca atggcgtcgt atatatatct ctcaacgatc ctattagcag tacttgctat
     7681 acaggttgcc gttagatctc catgagccaa aatcagtgct aaacgttttt gctgaaattc
     7741 tttactacac attaacttaa ataaaataac caaaacattt ttttgaattt ttgttaaata
     7801 aatatcccct atttgaataa aacgattgac taattgaact tctcgactac accaactatt
     7861 aatatcattg atgaaggaat ataatttatc gtccgatgtt aattggattt gataaatcca
     7921 agaattcaaa aagatagacg ttatttgaag ataataatag tcaaattcta tttgaaaatc
     7981 tctctctatt tccttaacat actgtctaaa tcgaatctct tgataggtgg gatatgttaa
     8041 agctgaatta ttttggatat caacattctt ttgtctaaaa tatctatcat atttctcaaa
     8101 aagctgctgc ttatcagtgt ctttcttcca cgtttgataa agatactcta taagttcgtt
     8161 gatattaaaa acttcgtcta ctttttccaa atcatccatt tgaatatatt ttaattcatt
     8221 ctgtcttttc ataaccttca tgccgttgaa attcacccat tgtggtaaat gatacatctg
     8281 aatataaagt tcttccaaat catctaagaa ataaaaggca ttggcacagg tcaattgaat
     8341 gatatttttc aaattgccaa cattttcact aaagcgatag tttaataaaa aatctaataa
     8401 ttgttgagat atcagtattt tctttgctag tctttcttct tctgatttaa aaaatatctt
     8461 gattaactgt tttctttcat aaagagaacg actgtctaat gttggaagtg ttagctttac
     8521 aggtattctt ctcaacaaag ttgataatag tttatcctca ggtggttctg atgttgcaaa
     8581 tataatccag caacttgatg tgtaccagtt ttcattatca cccatccgat gaaatttcct
     8641 cgtatccata aactgaaaaa gtttctcctg acattcattg ctcaatgcat gaatttcatc
     8701 taaaaataag actccattat tagctaattc tgctaaaccc tttcttccat cttcggctcc
     8761 tgtatatgca ccttttacat gcccaaaaaa attggacaag aaaagttctg gattattggc
     8821 atattcacta caattaactg aaatgaaaga tgccttctct tctatataat tattggccaa
     8881 caaatcctta tacacataat ttgctaaata gctttttcca gttccagtct cgccatgaag
     8941 taaaatgggt aagccatttg gcggatagta gattgctgct ttaatttgag caattacatt
     9001 tcgcagactt ccttgacttc cgataaccct ttctattcca accctaaaag agctatcata
     9061 ccatttttcc gcttcctctg aagagctaaa aatttgttga tttggaactt tctccggtaa
     9121 agaaaagaag attactggac gagtattgat ttttccaaat tctccatctt ttacgaattc
     9181 attcaaatat tgagagacaa tattacgact aacatttaat ttttcagata ttttctgtgc
     9241 tgtattgttc ccccatttat ttttaatctc agagttctct atgacataat tgacaatgcg
     9301 ttcttttaat tcttccatca cagcacctcc tcgacactat tcgaattttg ccgacagtat
     9361 ttttccataa atatgacttg ctaaaaaggc tttgtttaga tcattcaatt ggaacgttgc
     9421 ttgttttgct tgatccgcta agacgttgaa aagatactct ggcgaaatcg cataccccaa
     9481 aatatcaacg attgttgcaa tcagatcttc ttttgattct tcatctgaaa gtaattcacg
     9541 atacaacatc gtttgtttgc ttactgtgtc atattcctct aaggattcat ctgctaaaag
     9601 aaccacttgt tccaacaaac ggtcggataa atatttatag aaaatcagcc ccaataaata
     9661 atttttatat tctgacgcat ccattttact acggagatta tctgccgcac taaataactt
     9721 ctgatttaat tctgcaccca aaaagataca ctcctatctc ttatttaaag ttgctatata
     9781 ccctcttatt ttagcatact cagttttaga aaaagcaaaa aaataaagaa acttattctt
     9841 gataacaagc tacgtgacgt atatccctaa cacaaaaata gccatatcct ttggtttgga
     9901 tacggctatt tgatattact cattcaatta tcaaatcaca gtaggtgtga atctcatcgg
     9961 gatcggcaat atctacttct gattaggatc aaaggtgatt ttctcaataa aggtgtgata
    10021 caaagcttta acttgcttct tctcactctg gataagaaag caatccaaac tagtcaatat
    10081 ctgttggaca tctttgactt gaatcggttc cccttgttgt tgaaagatcc ctaagatttc
    10141 attctctcga atttgtaact gtcttcgttt ttcagtcaat tcatttaaac gatcttttaa
    10201 catcggaaac aattcgggac tatcttccaa agcagcttcc tgtttttgct ctaatagtta
    10261 gattttgcgt accattttct tcttttattt tccttcgatt gctgatttta atatagtcta
    10321 aaggaaattt atatttattg tattctttat aacttcaaga gaacttcgtt tgagtattac
    10381 tgtatttttt taattccata agaaaattag ttattacctg ccacctaatc agcaa
//
LOCUS       DAFLWZ010000088        10303 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000088 DAFLWZ010000000
VERSION     DAFLWZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.090"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..1072)
                     /locus_tag="L1V38_002454"
     CDS             complement(<1..1072)
                     /locus_tag="L1V38_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1316958.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNY"
     gene            complement(1063..1731)
                     /locus_tag="L1V38_002455"
     CDS             complement(1063..1731)
                     /locus_tag="L1V38_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1316959.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(2187..3173)
                     /gene="lacD"
                     /locus_tag="L1V38_002456"
     CDS             complement(2187..3173)
                     /gene="lacD"
                     /locus_tag="L1V38_002456"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1316960.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(3186..4112)
                     /gene="lacC"
                     /locus_tag="L1V38_002457"
     CDS             complement(3186..4112)
                     /gene="lacC"
                     /locus_tag="L1V38_002457"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBN1316961.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(4125..4640)
                     /gene="lacB"
                     /locus_tag="L1V38_002458"
     CDS             complement(4125..4640)
                     /gene="lacB"
                     /locus_tag="L1V38_002458"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBN1316962.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(4659..5087)
                     /gene="lacA"
                     /locus_tag="L1V38_002459"
     CDS             complement(4659..5087)
                     /gene="lacA"
                     /locus_tag="L1V38_002459"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBN1316963.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTREHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(5107..5880)
                     /locus_tag="L1V38_002460"
     CDS             complement(5107..5880)
                     /locus_tag="L1V38_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1316964.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            6045..6524
                     /locus_tag="L1V38_002461"
     CDS             6045..6524
                     /locus_tag="L1V38_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1316965.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            6581..6883
                     /locus_tag="L1V38_002462"
     CDS             6581..6883
                     /locus_tag="L1V38_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBN1316966.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            6905..8362
                     /locus_tag="L1V38_002463"
     CDS             6905..8362
                     /locus_tag="L1V38_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1316967.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(8955..9707)
                     /locus_tag="L1V38_002464"
     CDS             complement(8955..9707)
                     /locus_tag="L1V38_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1316968.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(9922..10158)
                     /locus_tag="L1V38_002465"
                     /pseudo
     CDS             complement(9922..10158)
                     /locus_tag="L1V38_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(10168..>10303)
                     /locus_tag="L1V38_002466"
     CDS             complement(10168..>10303)
                     /locus_tag="L1V38_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1316969.1"
                     /translation="DTDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI
                     "
BASE COUNT         2924 a         2255 c         1760 g         3364 t
ORIGIN      
        1 gataatttaa tgattttctt ggaatatggt ttcttttcga ggcaacggat tgaataaagg
       61 tttcatccgt gtccctaaag tccattgttt taggtaagcc atcctgcttg agcccatgca
      121 ctcggtactg atgagaaaaa attgatgcct gtttctcctg aggaatgcca attccctgat
      181 cttttacttc aataatcacg ctaccctttt ggtttgaaat ggtgacaatt accagttttc
      241 cttcaccata tttgattgca ttgtcaacta aattcgaaac cgcccgataa atccaacgat
      301 ctcgtccatg aatcagggtt ggttgatctt cagtaaacgc aaacaaaaga ttcggataat
      361 tcattttgta ggcatcacaa acttccgcac agatcagtga aacgtctacg acttccgtgc
      421 taagatcctc tgagttattg gataatgtca aaatatcgtc aatactgtcg gtcatccgat
      481 ctaaaagcat taaatttcct tgatcggcat gttgccgttc tatttccaga ttcgtacgca
      541 aaatagcgat ggcatttttc tgctcgtggg tcagataact atttaatcgt cgataatcct
      601 ccaaatgacc atcgaactta tcctttagct tattaaaagc cgcatttaat gcctcgtcct
      661 tcacagtatt tttaggaact tgatcaataa acgttaaatc acgcgtaatc gctaagattt
      721 gattactgta aattttgcgt aaaaccaacc aaagaataaa cgttaataac atgacggcag
      781 aacaaataac cagcaccatc gctggtaaat atttaaatag ttcgtcctgg taagctttat
      841 ctatcatcga aatagtcata aattgattgt tggaagattt cgaagcttcc atctgcgtct
      901 ctgcttgaac cgtcttaccc tcttccataa aataaacatc ttcacctaag gtagatgcga
      961 tactgattcc ctccaaatta tttctcagaa agaagaaact cactaaaatc acgcctgtca
     1021 ccaacagtga aaaagccagc atcgttaacg tcattttaaa atttaatagc atagctggta
     1081 cccctttgct cgaatggttt ttaagacctc tttttcagct gcttcagcca gtttcttttt
     1141 tagacgagcc agatgcactc gcagaaccga cgaaaaagga tcaaaatctt catcgtagac
     1201 atgttcagaa atttcctcag acgaaacaac cgctggatga cgctgagcga tgcacagtaa
     1261 gatatcaaat tccttgggtt tcaggaccac ctctgtcttt tgatagctga cccttcgacc
     1321 taatggatca atcttcaaag caccaattga aatctgcggc agcgcacgtc catgataacg
     1381 acgaataacc gcgcgtattc gtgcttttaa ttctagtaac tcaaagggtt tgactaaata
     1441 atcatctgct ccaaaatcca agccttttgc tcgttcttca atctcatcac gtgcagtaat
     1501 aatgataact ggactttcga cttcttcagc acggagactt tgtaaaacag ataatccatc
     1561 ttttttaggc agatttaaat ctagtagtat cccatcgtat gaattgatga aggccttctc
     1621 ttctcctgac tcgccatcat aagctacatc tacagaaata ttctcctgct ctaggccctt
     1681 ttttacggat aaaaccagct cacgattgtc ctcaaccacc agtacacgca tgtatattca
     1741 ctcctcatac ggatttagta attacactta tgctttttag catagtacac gctcttcttc
     1801 aaagtccacg ttctttttgt gaagatttga agaaattcat acattctgtt aaaaaacaca
     1861 taattaagaa tgattttact gtttgaaaat acctagaata gaaaaagact ggaacctttc
     1921 ctccagtctc actactttct atttgcttgg ttttcttgta tatacttttc aaagttcgtt
     1981 ggtttatgac caataagcct cgttagaata ctgaaaattg ccatcaagtc attaagtacc
     2041 acatgtaaga aaatctctct aaagaaaaac cccttcgttt taactcactt actattttag
     2101 aattcgttcc cctaataatg cagcatgatt ttacgcttta tgtataaaaa aagactgcaa
     2161 gcaattgtgc ttcacagtct gatttcttat gatagtgagc ttgttaacac ttccaccggt
     2221 gtagcagttt ctttcaatac ggcatttaat tcttcaatat ttttacgccc ttgcgtattc
     2281 atccactcca tcgctgcttc ttttccatca acgatatagc tttctacacc atctgcccaa
     2341 gtcgcacggc cgcaaagtac accattgaag gttgagccgg catttttcgc gaagcgcagt
     2401 gtttcttgga acaactctgc ttttacaccg gcgcttagga aaataaatgg caggttagtg
     2461 gcttcagcct gttccttgaa gaagttagcc gcttgtgcct ttgtgtacac gacttcgtct
     2521 gtcccatagc cttccacata attcatattg acgggtactt ccacctttaa cacatctacg
     2581 ccataacgtg gatcagaaaa ttccttcatc atatcgttga ctttatgagg tttcttaatg
     2641 gcgtattctt tcgaagtcgc atcagagatg ttcgcgtcat aagaaacaag ctccaagaag
     2701 aagggtaagt tttcagcctg acattctgag ccgattcgtt caataaaggc atgtttttga
     2761 ttattgattt cttctgcttc atcgacatca tagtaaagta ggaacttaca agcatcggcg
     2821 cctgcttctt ttaaacgttt aactgaccag atcgataata aatctggtaa acggccggga
     2881 gttgacgcat cgtaaccagt tttttcataa gctaacagca agccggcatt ttttgctcta
     2941 acgtcagctg ctggcaagcc atattcggga tctaataaaa tcgatgaggc atatttcgtt
     3001 aattgtgaag aaacaatttc tttaaattca acgatttctg attcttctgc ttcgctgccc
     3061 ttgaattttg tgatcatctt cttcaaagcc ccgcgttgat caattgctaa ggccccaatc
     3121 actccatctt cattgcatag ttgcttgata tattgacgtt tttcttcgtt catttccgta
     3181 tcctcctaca ctttctccac taagatttga tcatatagtt tttgataatt ggctaattgg
     3241 acatagccag tcgtcgcttc ctgagcattc agcattccta aaacattacc ctgttttaac
     3301 acggcttcat ccgaaagacc ttgttgaatc gcagcggtca atccggcaac ggtcgcatca
     3361 ccagagccaa ctggattgac gacatcaatc tttggaattg tcacgcaata aaaagtctcg
     3421 tgatgtttgg caaaggctcc gtcgcccccc attgaaacca ctatccattc aatttcatca
     3481 aacatcgaat ctgacaaggc ggcttttaaa tctgataatt ctgttgagat ttctcgtcct
     3541 agcagaccag ccagctcttc ggtattgggt tttattagct taggctttac actgcctcgc
     3601 aacacttccc ttaatgctgt acctgaacaa tctaaaacga caggctttgg ctgacaaact
     3661 tgcagcattt gtcgataaaa atcagcaggc aatccttctg gcaagcttcc tgaaaaagaa
     3721 atgatttcgg ctttaacagc taatttttcg aaatgttgca agaacgccct tgcttcttgt
     3781 tcagtaataa caggtccgtt ttctaggatt tccgtctgtt ttccgtcatg taaaacagcg
     3841 atgcaattac gtgtctctcc gctgataggt aaaaagtcat gagcaatctc attttgagtc
     3901 aggtcctttt taatctcttc acctaaaaaa ccgccgatta aaccactagc aatcacctcc
     3961 gtatctaatt gcttcaagat acgtgtcaca tttaggccct taccgccagc tgttttgcga
     4021 acatttctta ctcgattgac tgtgtcgagc ttgaaggttt ctaatggata agaaatatca
     4081 atcgatggat tcatcgttat tgttaaaatc atttgtccac ccgcttaatc gtggtattcg
     4141 ccacgatccc atttctcgat aaattcatcg aagaaatgcg gatcagactg cttgtcactg
     4201 gctttttcga cgtgatcgat tttggcgatc aattttttgt tttcttcagt ttcttgataa
     4261 tcggcattga tgaaggcctc taatatgtca cagatcaaaa attctcccgt aatccgagcg
     4321 ccaaagccga tcacattggc atttagttgt tccttcgcat agatagcagt cgtcatatcg
     4381 cgaaccagcg cactgcggat accaggtact ttattgacag cgttgttaat cccaacacct
     4441 gttccacaca aacaaactcc tagatctgct tctccgctag tcacggcctc tccgactttt
     4501 tttccgtaga tcggataatg ggttctggta aagtcatagg tccccatatc caacacttca
     4561 tgtccttttg attttaagaa atctgatact gccatttttg tatctgtgac gatgtggtca
     4621 cagccaattg cgattttcat ttcattcatc cttcctaatt acgccatttt atttaacatg
     4681 tcgacacgta cttgatgacg accgccatca taatttgctt gtagaaattc cttaacaata
     4741 ttcaacgcca actcatcgcc aacaattttt gatccaagtg tgatcatccg agaattatta
     4801 tgttcacggg tcatatacgc actgcgctca tccgaaactt ctgctgctac cattccttta
     4861 acctttgttg ccgtgataaa gctgccagcg ccgtagccat caaccgcgat tcctaaacta
     4921 ccttcgtttt cattcagatc atttgcgatc gccaaagttg attccacaaa atcttctgaa
     4981 gccgtttcac tcttatctac tactgtaata ccttctttga tcaatttttt cttgattaat
     5041 tcctttaatt ccatgccgtc actgtctgaa ccaattacta cacgcatttt tgtttcctcc
     5101 tattttttac tgaatgattt tagtgaattg ctgataataa ctcttcagct cggctgaaag
     5161 agtagaatcc gtaaataatt tgtcgatctt gcgcaaatca tagaaattat aaaaatcgct
     5221 atggtcgaat ttgtttgcat ctgaaaccaa acatttttct gccgcattat ctaaaacaat
     5281 tttttgcaag gtaccttctt caatactgaa attcgaaacc tccgaaccct tcaatccatt
     5341 cactccgaca aaagccttct taataccgat tttttgaaca gcttcattgg caattgaacc
     5401 gacaaaggct ccagtctttt cccgatatag cccaccgatc aaatacagtt caaatctttt
     5461 tatttcactt aatagattga aaaccggcag actattggta acgattcgga gagatgacgg
     5521 cttgatgtat cgtgtcatta attcgatcgt tgtacccgat ccaagaaaaa tcgtgtcgtc
     5581 ttcttgattg atatgagctg ccgcattttt agcgatgtat tccttctctt ttgtatgcag
     5641 cttctttttt tcagtatgag aaagctcatt tgcttctata gaagtcgaca tttccagata
     5701 atcgattttt tgtgcaccgc catgaacgcg taaaagcttt ttcttctgcg cgagttcctc
     5761 tagatctcgg cggatcgtca tatctgaaac attcagtact tcctgaataa atttgactgt
     5821 tatcgtccca tagcgatcac acatcgctaa gatcgaacgc tgtcgttctg ttttcagcat
     5881 attctgtacc tccacgacct tataataaaa catttacgaa catttttcaa cacatattgt
     5941 tcgtttattt tcgtttatgc gttgacaata attttgtaag cggttatact caacttgtaa
     6001 acagataaat aaacataaac gaactaataa aggagctgtt ttgtgtgaat gaattctttt
     6061 tcaaagacac tgtctatgtt tctgacaagc agtcgcagga agaagtgttc gaggaagtct
     6121 atcaagatct gttaaagaaa gaattggtaa ccgaagattt tttggagaac cttttagaac
     6181 gggagcgtaa ttatccgacg ggattagatc tctcacctgt ctctaaaata ttgccagata
     6241 tcgctatccc tcataccgaa agtgagtttg tgcgaaccac ccgtatcatt ccaatcaaag
     6301 taaaaaatga aatccctttc tacaacatga tctcgccaag cgatcagatt tccgcttcat
     6361 ttcttttcat gatcttgaac gaaaatggtg aagcacaggc tggcatgttg gctaatatca
     6421 tggatttcat taattctgtt gacgaagaaa aactgttttc gtttttcaaa ttagaggaca
     6481 cagaagcgat ttatcatttt ttagaagaac atttttatat atagaagtct ctgcctaacc
     6541 gcaggataaa aaataaactt attttaaggg gagaattatt atgatcaaaa ttttagcagc
     6601 atgtggagca ggcgttaatt caagccatca aatcaaaagc gctttggaaa ctgaattgaa
     6661 aaatcgtggc tatcaagtca cctgtgacgc cgttatgatc aaagatatca atgaagaaat
     6721 gctgtctcat tatgacattt tcgcacaaat tgccaacacc gacttgggtt ttgacattaa
     6781 catccctgtc gttgatgcag gtgctattct ttatcgtatt cctgctatgg ctgagcctgt
     6841 ttaccaaagt atggaaagcg caatccaatc attaaacaaa taggactaaa gaaaggaaaa
     6901 gcatatgaat acaattattg atattgccaa taaagtattt acccccctaa ttaatttagg
     6961 tgcggcaccg ttaatgacca tcgtattaac tgttattgct ttatttttta aagtaaaacc
     7021 gtcacgcgct cttgaaggcg ggctcaaatt agggatcgcc ctgactggga tcggagctat
     7081 tattggaatt ttaactactg ctttttcaga cgctatgaca gcttttgttg aacgcacagg
     7141 tatttcatta aacattacag atgtcggttg ggccccacta gcaaccatca catgggggtc
     7201 gccatacacg ctttattttt tactaattat ggtgatcgtc aatattgtca tgttagcaat
     7261 gaaaaaaacc aacacattag atgtggatat tttcgatatt tggcatttag caattgttgg
     7321 tttgttcgcg atcttctgcg gtgctaatct gtttattgct tctgcattag ttattttcat
     7381 tggtgtatta aaaatttgga actccgactt aatgaaacca accttcaatg acttgttaaa
     7441 tgcgccagac agcaacccga tgaccacgac tcatatgaac tacatgatga atccgattat
     7501 tatggttttc gataaaattt tcgacaaaat cttcccttgg ttggataaat atgatttcga
     7561 tgctgccaaa ttgaatagta aaattggctt ctggggatca aaattcgcga ttggaattta
     7621 tttggggatt tttgttggat tactagcagg acaaacacca acgcaaattt tctcgctagc
     7681 ctttaccgct gccgtctgtt tggaattgtt ctctttgata ggcgcttggt tcatcgcagc
     7741 cgtagaaccg ttatcacaag ggattaccga ttttgccaat aaacgactaa aaggacgtac
     7801 catcaacata ggtttagact ggcctttcat agcaggccgc gctgaaatct gggctgccgc
     7861 taacgtatta gcaccaatca tgttgctaga agccatcatc ttaccaggaa ataaattatt
     7921 gccactaggc ggaatcatcg caatgggtgt taccccagca ctattggtcg taactcgtgg
     7981 aaaattaatc cgtatgatcg taatcggcgc gatcgaatta ccattattct tatggtccgg
     8041 caccttgatc gccccgttcg ttactcaaac agctaaagca gtcggagcct ttccagccgg
     8101 cttgaacggg tccgccatga tctctcatac aacgatggaa ggcccgattg aaaaattcct
     8161 aggttattta gtcggtaatg cttctcaagg acaaatcgaa tttgtgatat acgctgcctt
     8221 agcattaggt gcataccttt taatcttcat ttggtacgct cgtcaaatga aaaaacgcaa
     8281 cgctgcatac gcagctgaaa aagaagagaa tgcatctccg gcaacggcgc ataatatgac
     8341 ttatgcagcc gaagctaaat aagctaaaaa caccccgaat gtctttagac ttcggggtat
     8401 tattttacct ataaaaaata aatagatgta aaatccattt caaaaagcat agcccatctc
     8461 ttgccacacc caataaagaa attatcaacg tttatgcttt ttttaactcc tttaagcttg
     8521 cctttgttgg tattcctcaa cgattctttt tgtgttcttg tttgttttgt gctttttgac
     8581 tttttgttgt ttaattgcga attccttgat ttcttttttc ctgaatcgct tcgcatcccg
     8641 cggttatgcg tgcgatttca tcattgcttt ttctgatcta actcgtttca tgtcaaagag
     8701 cttcagctga cttagtgtcc atggttgttt tgatatccct tttcctcctt aataaagcgg
     8761 tgattgatac tgctattttt tccttcacat aaacataaca tcccaaaaaa atcgactatc
     8821 ttttttcaaa tggtgtattc aagtattcgg aggaattagt aatgatgcac cctaaaaata
     8881 acataattcg cttaaattca aggctaccaa aaaactacca agttctaatt atctagagtt
     8941 tggcagtttc tcatttacac aacatatttt tcttcttttt cgattttttc atagtgcttt
     9001 tgttcatcat catccgttat aactactgtt acatcattca gattataata tactgaaaaa
     9061 tctcttttcc caattttcga atgatcaatc aataaaaagc gttcaacaga attattcaga
     9121 gcgatctgtt gagtttggcc ctcttcaaaa gtcgaagtca taattttctg ttcatttaaa
     9181 gcattacagc tgaaaaatgc tttatgaaaa ttcatatcct gtagcgattt attcgtgatt
     9241 tcaccaacaa agcattgagt cgtttcccgc atctcgccac ctaatagata gatttttcga
     9301 ttcccttttc gcttatttaa ttcttcaaaa acaggcaaac agtttgtaac aatccgcagt
     9361 gaatcccctt gaatgatttt tgacatgagc tcgattgtag ttcctggtcc aagaaatatc
     9421 gtatcaccat cattgatcat ttcattcgcc ttttccacaa tccgctgctt ttcttcttgc
     9481 agcataatct gtttttctct atgagaaagc tccacatgcc gataaaaatc cttcaatttc
     9541 gctccgccat ggacgcgttc taataatcct tgtttctcca tttcgtccaa atcacgtcgg
     9601 actgtcatat ccgaaaccga aaacttctcc ataatatcgc tgactcgtac tgtaccgtta
     9661 acctctaata acgacatgat cgcttggaat cgatccgttt ttaacatttc atcgcctctt
     9721 ttctttttaa gactatcaaa ttcttaagaa aagtgctaga acaagttttc ttaagaagcc
     9781 ttctgcagga aggaaagcaa aatttttcag aatttgcaag ctgctattct aaaaaataaa
     9841 accgaacgag catgactgtc atagtgacag ccttgttcat tcgactttta tctttaataa
     9901 atcattttat ttaatctgaa gttattgtgc aagttcaaaa acaaagtagt taatgtctcc
     9961 tcgatatttc gaaatcgaat actcaacggg cagacgttct agcgaaaaac cctgcgtatg
    10021 gaaatagaac attggatctc cttcttccac atctaacaaa tcgctgatcg tatcatccgc
    10081 tttgattact tctagttttc tggtgaccgt tttaattgga taacccattt cttcaaaaac
    10141 ttgatacatt ttttcttttc tgatttgtca aattaagcta gacaatatgt ctttatctat
    10201 gcagctcaaa aatacttcca atggtgttcg ataatttaat gattttcttg gaatatggtt
    10261 tcttttcgag gcaacggatt gaataaaggt ttcatccgtg tcc
//
LOCUS       DAFLWZ010000089        10080 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000089 DAFLWZ010000000
VERSION     DAFLWZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10080
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.091"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(109..2229)
                     /locus_tag="L1V38_002467"
     CDS             complement(109..2229)
                     /locus_tag="L1V38_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1316970.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="L1V38_002468"
     CDS             2459..3637
                     /locus_tag="L1V38_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBN1316971.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="L1V38_002469"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="L1V38_002469"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBN1316972.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="L1V38_002470"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="L1V38_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBN1316973.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="L1V38_002471"
     CDS             complement(4990..6243)
                     /locus_tag="L1V38_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1316974.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="L1V38_002472"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="L1V38_002472"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBN1316975.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="L1V38_002473"
     CDS             7821..9167
                     /locus_tag="L1V38_002473"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBN1316976.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="L1V38_002474"
     CDS             complement(9475..9861)
                     /locus_tag="L1V38_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1316977.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10080)
                     /locus_tag="L1V38_002475"
     CDS             complement(9910..>10080)
                     /locus_tag="L1V38_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1316978.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2052 g         2974 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
//
LOCUS       DAFLWZ010000090         9940 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000090 DAFLWZ010000000
VERSION     DAFLWZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.092"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..173)
                     /locus_tag="L1V38_002476"
     CDS             complement(<1..173)
                     /locus_tag="L1V38_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1316979.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="L1V38_002477"
     CDS             complement(593..1714)
                     /locus_tag="L1V38_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBN1316980.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="L1V38_002478"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="L1V38_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBN1316981.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="L1V38_002479"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="L1V38_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBN1316982.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="L1V38_002480"
     CDS             complement(4304..5215)
                     /locus_tag="L1V38_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1316983.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="L1V38_002481"
     CDS             complement(5232..6239)
                     /locus_tag="L1V38_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1316984.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="L1V38_002482"
     CDS             complement(6236..8365)
                     /locus_tag="L1V38_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1316985.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8495)
                     /locus_tag="L1V38_002483"
                     /pseudo
     CDS             complement(8370..8495)
                     /locus_tag="L1V38_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(8666..9853)
                     /locus_tag="L1V38_002484"
     CDS             complement(8666..9853)
                     /locus_tag="L1V38_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBN1316986.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT         3019 a         2043 c         1739 g         3139 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttttcagtca agtccacaat cttgtgtaaa
     8521 agttcaacct catcaaaagc acaatgtttt gcgttgtgaa cctaactgcc atgcctttct
     8581 ttctgaggag agaggtcagg agcagtagcg cagcgactct tgatgtctct cctcagaaag
     8641 aagagactcg cacaggttca tggtgctaaa tgttattcga attaaattct aaatattttc
     8701 gtggagaagc cagccactca gtgtcttttt ccatcaaaag tgttccaatt atccgagtga
     8761 tggaattgat atttggaaaa atccgaatca ctcgttctct ccggcgaatc tcttcgttca
     8821 accgttccaa cacattggtt gtacgaatcc ttcggcggat attttcagga aaagacaaaa
     8881 tttgaatagc atcttcaaag ccgttttcta aaatgtcgca agcagcactt aattttgaat
     8941 cacaaccata tttttccaag aagtgctctt ttctttcacg tgtcaattca agttcagagg
     9001 ctttaaagat actcttcaac tcgtctttta catcagaaga aactttcttt ggcagcttat
     9061 caaaaatatt tctcaaaaag tgggcttggc atctttgcca gctcgcacct aaaaagttct
     9121 tgcgaacagc cttaactaac cctttgtgtg catcagaaat gaccagtttt acaccgaaca
     9181 aacctcgttg aacgaacgat tgaaaaacgg tatcccaatt atcttccgat tcgccgtctt
     9241 gaacatcaaa accaagaatc gtacgtcgtc catcagaatc aatgccgata ccaatatata
     9301 caccttttga gacaatacga tgattttccc ttactttcat atacagggca tcacacatga
     9361 aaaatggata ttccgagcct tctaggctcc ggtttctcca ctcaaaaaca aatggatcca
     9421 actgtttcat cagatttgaa acgaatgatt tagaaacagt cgcaccatcc gttagcagtt
     9481 caactgtttt agttactttg cgagtggaga caccagaaat gaccatttca atcatggcag
     9541 cgatcaaagc tttttcgctt cgctgatatc tttcaaagat agtaggacta aacttaccgt
     9601 ctctggttcg tggaacatga agttctaacg taccaattcg agttgtaaac gaacgatcgt
     9661 agtaaccatt tctttgtgat tgccgttctt ctgaacgttc ataggcattt gcctgaatat
     9721 attgatttcg ttgttcttcc atcagctgat taaacatgat agtcataagt gtttttgcgg
     9781 tatcattcgc accgctttcg tttataattg cttgaatttc ttcgctttca aaagtaaaat
     9841 gtacttgagt cattgatatc agtcctattc gagtatgttt tctgcaaaaa acattgtact
     9901 cctaactgag atcaatggct tttttgatgc ttcactttta
//
LOCUS       DAFLWZ010000091         9927 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000091 DAFLWZ010000000
VERSION     DAFLWZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.093"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            137..994
                     /locus_tag="L1V38_002485"
     CDS             137..994
                     /locus_tag="L1V38_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBN1316987.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="L1V38_002486"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="L1V38_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBN1316988.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="L1V38_002487"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="L1V38_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBN1316989.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="L1V38_002488"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="L1V38_002488"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1316990.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="L1V38_002489"
     CDS             3750..4508
                     /locus_tag="L1V38_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1316991.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="L1V38_002490"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="L1V38_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBN1316992.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="L1V38_002491"
     CDS             5436..5735
                     /locus_tag="L1V38_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316993.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="L1V38_002492"
     CDS             5761..6468
                     /locus_tag="L1V38_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1316994.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="L1V38_002493"
     CDS             6465..7232
                     /locus_tag="L1V38_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1316995.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="L1V38_002494"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="L1V38_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBN1316996.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9197..9517
                     /locus_tag="L1V38_002495"
     CDS             9197..9517
                     /locus_tag="L1V38_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBN1316997.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9517..9867
                     /locus_tag="L1V38_002496"
     CDS             9517..9867
                     /locus_tag="L1V38_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBN1316998.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         3198 a         1693 c         2131 g         2905 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttc
//
LOCUS       DAFLWZ010000092         9615 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000092 DAFLWZ010000000
VERSION     DAFLWZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.094"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            112..306
                     /locus_tag="L1V38_002497"
     CDS             112..306
                     /locus_tag="L1V38_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1316999.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="L1V38_002498"
     CDS             575..874
                     /locus_tag="L1V38_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317000.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="L1V38_002499"
     CDS             complement(971..1405)
                     /locus_tag="L1V38_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1317001.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="L1V38_002500"
     CDS             complement(1637..2347)
                     /locus_tag="L1V38_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1317002.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="L1V38_002501"
     CDS             complement(2337..3197)
                     /locus_tag="L1V38_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBN1317003.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="L1V38_002502"
     CDS             complement(3202..3840)
                     /locus_tag="L1V38_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBN1317004.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="L1V38_002503"
     CDS             complement(3855..4154)
                     /locus_tag="L1V38_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1317005.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="L1V38_002504"
     CDS             complement(4197..5681)
                     /locus_tag="L1V38_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1317006.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="L1V38_002505"
     CDS             complement(5701..6162)
                     /locus_tag="L1V38_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1317007.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="L1V38_002506"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="L1V38_002506"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBN1317008.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="L1V38_002507"
     CDS             7465..8235
                     /locus_tag="L1V38_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1317009.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="L1V38_002508"
     CDS             complement(8508..9335)
                     /locus_tag="L1V38_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317010.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2999 a         1959 c         1504 g         3153 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac agcac
//
LOCUS       DAFLWZ010000093         9513 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000093 DAFLWZ010000000
VERSION     DAFLWZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.095"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            103..882
                     /locus_tag="L1V38_002509"
     CDS             103..882
                     /locus_tag="L1V38_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317011.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            928..1872
                     /locus_tag="L1V38_002510"
     CDS             928..1872
                     /locus_tag="L1V38_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1317012.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1888..2667
                     /locus_tag="L1V38_002511"
     CDS             1888..2667
                     /locus_tag="L1V38_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBN1317013.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2679..3377
                     /locus_tag="L1V38_002512"
     CDS             2679..3377
                     /locus_tag="L1V38_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBN1317014.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3405..4169
                     /locus_tag="L1V38_002513"
     CDS             3405..4169
                     /locus_tag="L1V38_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1317015.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            4183..6000
                     /locus_tag="L1V38_002514"
     CDS             4183..6000
                     /locus_tag="L1V38_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1317016.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            6054..6977
                     /locus_tag="L1V38_002515"
     CDS             6054..6977
                     /locus_tag="L1V38_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBN1317017.1"
                     /translation="MNAFKTALNNNEMEGKILGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYID
                     NPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKK
                     MLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKN
                     LRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            6949..7665
                     /locus_tag="L1V38_002516"
     CDS             6949..7665
                     /locus_tag="L1V38_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1317018.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            7662..8780
                     /locus_tag="L1V38_002517"
     CDS             7662..8780
                     /locus_tag="L1V38_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1317019.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            8770..9390
                     /locus_tag="L1V38_002518"
     CDS             8770..9390
                     /locus_tag="L1V38_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1317020.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
BASE COUNT         3441 a         1527 c         1906 g         2639 t
ORIGIN      
        1 aatatattaa tttaattatg ttttttaaaa taaaaagctg tcatttttat gtatgtgaat
       61 tatatcttaa tttatctatc atcaatactt aggagtgaat ctatggaaaa gccattcgtc
      121 aagtcattga ctgctgtggc ggtaggtgca ggtgctattg cgatctgttt gtttggttac
      181 catatcaata atcagcggca acatcagcaa cggatcaatt atgcagaatc tgccatcacc
      241 aatcaaaaag acaccttgac ttctttatca aaagaagtag acaagctgta tagtacaaaa
      301 gaaaaaaatt ttctaaaccc tgaaataaca gaagaaacaa tcacaagttt gtcaaataag
      361 ctatcctctg tcaaactttc agcagatgat tacgacatca aagaatcaga attgcctaaa
      421 gaagctgttg caatccaaga tgagaagaaa gcaatcgtga cacagttaga tagtgcagaa
      481 tcaaaactga agatccagac agctgtcaac gatttattta ctaaaaatgt atcaaactgg
      541 cagcaagctg tagacgatgt cgtcatcaaa gaaaaggtga caagtgcaga tgtcgctcgt
      601 gtacgtgaaa atatgagctt ttttaaagat agtccttgga aaacggttgt tatgcaatat
      661 ctaggattcg ctgatactca gatcgcgcaa gtcacgcaac tagatcagtt attcgatacg
      721 atgttgaagg atggtcaagt gactgccacc gctacttacg atcaatattt gacggcgctc
      781 agtcaaatag agcagatccg gaatgaaaaa ataagcgcag catacgcaac aaaagcacaa
      841 actgttgctc agcaaatggg ctatagcaat ataagttatt gacagttaaa acgttgattc
      901 aagcaaggtt agcaaacgga ggaaactatg gcaagacgaa gaagaaaatc aagagggaaa
      961 aaaatatttc tgattatttt agcagttctt atcgtattag tattagcaat tgtaggagta
     1021 ggagcaaaat tatatctgga tctctcacat tctattgaga aaacttacga atcagtggaa
     1081 cgaacccaag gagaacgaac gaaaccagtt gatctggaca aacaagaatc tttctctgtt
     1141 ctattgatgg gcattgatac tggagattta ggtcgggtcg atcaaggaag atcagatacg
     1201 atgatggttg ccacagtcag tcctgaagac aaacagacaa cgatcgtcag cattcctcga
     1261 gatacgtatg tcgacatcgt aggtcgtgac acaaaagaca agatcaacca cgcttacgca
     1321 ttcggcggag ctgccatggc gatggatacc ctacaaaaat atgtagacat cccaatcgat
     1381 cactatgtct ctatcaatat gaaagggcta aaggaactcg ttgatgcagt tggtggtatc
     1441 gaagtcaata atgacctcac tttctcacaa gatggctatg actttccaat cggtaaaatt
     1501 acattgaacg gggatcaggc attatcttat tctcgtatgc gttatgaaga tccaaatggt
     1561 gactatggta gacaagagcg tcaaagaaag atcgtagaag gtgtagcaaa aaaagtattg
     1621 agtttaaacg gtgtcagcaa ctatcaatcc gttttgaatg ctctagagtc gaatatgaaa
     1681 acagacatga gctttgatga aatgaaaaaa atcgctttag attatcggga ggcatttggt
     1741 acgatcaagc aagatcagct gcaaggagaa ggcttcatgc aagataatat ctcctatcaa
     1801 aaagtcagcg atcaagaact tgatcgtgtg aaaaaagaat taaaagatca aatgaatcta
     1861 gagaataaat aggaaagtgg agaaaaaatg gaagagacaa tcagcttgaa agaaattttt
     1921 gaaacattac gcaaacactt ggtaacaatc atcatctcaa tgtttgctgg cttggccatc
     1981 tcaggaatcg taacattttt catcttgaca ccaaaataca gttcacaagc acaattgatc
     2041 gtgacactgc cacaatcaga cacagcaaat gtcaatgatg tcaatacgaa cctgcaaatg
     2101 atcaatacgt ataaagatat gatcgtcagt gatttagtac taaatgaagt caaagatcgt
     2161 ttagaaacag aagacaatgt gaaaatgact gctggacaaa tcaaagatgc gatctccgtc
     2221 aatcagtcac aaaattcaca aatgttctcg atccaggcaa taagcacgaa tgcagtgact
     2281 gctcaacaga tcgctaacac aacttcacaa gttttccaag agaacgcaaa agacgtgatg
     2341 aatgtcgata aaatctcgat tatttcaggt gcagttgcca atacgacacc tgtttcgcca
     2401 aataataaat tgaatctagt gattggctta gtattaggaa tgatggtagg cgtaggtctg
     2461 gcattcttat tcgaattact tgatcggaca gtgaaagatg aaaaatatgt gacggatgca
     2521 ttaggattcc caatcttagg aacagttcca gaaatgtcag cgaaagaatt gaacgctggt
     2581 atccgtaaaa aaggaacagc tcctgcacga ccaaaagcta caaacgataa aacagcccca
     2641 tcacgcagaa gccgctcaag agtctaggag gaagaaaaat ggcacgaaca cagaaacaaa
     2701 aagcagcaca aactcatgca gtcagtttga tcacattaac aaacccatct tcaccaatcg
     2761 ccgaacaata tcgtacgatc cggacgaata tccagtttgc ctccgcagct ggtcagcaaa
     2821 tcaaaacgat tgtcgtgact tcatcaggtc ctggagaagg aaaatccacc actgcagcaa
     2881 acattgcagt cgtttttgct aaatccggtc aacgagttct actagtcgat gcagatttac
     2941 gtaaacccgt cgtctataag acattccagc tgaacaatgc caggggatta agtacagcac
     3001 ttagttcatc aggaagtgta gcagatgtaa tccaacgaac gccagtcgag aacttgtcga
     3061 ttttgcctag tggacctaag ccacccaacc catcagaatt gttaagttcg ccaagaatgg
     3121 atcagatcct agacgaagca agacagttat ttgacgtggt gatattcgat atgccaccag
     3181 tagtagccgt aacagatgca cagatcatgt cttcaaaaac ggatggcact ttattggtcg
     3241 tacgtgaaaa tacatcacgt aaagaatcat tgaataaagc aaaagaactg ctagagatgg
     3301 tacaagcacg agttttaggt gttgtataca acggagcaga acatagcaaa gatgctggtt
     3361 attactacgg aaattaagga ataagaagag aggagacaag agaaatgatc gatctacatt
     3421 gccatatcct accaggaatc gatgacgggg cagaaaactt agaagcaagt attgcaatgg
     3481 ctgaaaaagc gattcagcaa ggcatcacgc atattttatg cacaccacac cacaataatg
     3541 gaaaatacag caatgaaaaa tcacaagtca tttctctagt cgcttcgtta caagccgaat
     3601 tagagaaaag acagttgcct ttgacgttat tggaaggaca agaagtacgt attaccggaa
     3661 cgctcatcga agacatccac cgagatgaaa ttttatttac agatttagat gatacatatc
     3721 ttctgatcga atttccgaca ctggaagtgc cgttatatgc agaacggctt ttttttgagt
     3781 tgttagaact aggaaagaca ccagtgatcg tccatccaga acgcaacgcg cattttcgcg
     3841 aagacccgaa tcatttgctt ccgttcctag atatggggtg tttggcccaa cttactgcgc
     3901 caagttatgt tggggtattt ggcaaagata ttcagaaaac agctaaaaca atggtcaaac
     3961 ataatctcgt gcagatgact gcttctgatg cacacggagt ctctaagcgc accttttact
     4021 taaaagagtg ctatgagcag attgccaagg actttggtaa ggaaaaagta gtacagatga
     4081 agcaagttgc aaaggatctg atcaacgggg atgaaatcag ttatccagac tatgaagagg
     4141 taaaaaagaa gaagtttggt ttattttagg gggaattaaa aagtgtttat attaacaaga
     4201 agaagaaaaa ttgccacatt ggtttttgtg gacagcttgt tattaattgc tgcaaatatt
     4261 gcagcagcta aattcatgaa gccgtttgta tctataccaa tggatcttat tttaatctct
     4321 atcggtttgt cgattggttt ttatttattt tatggtagtt tattcaaagt tttcactcgg
     4381 atcaatcgct atacaaattt aagagagatc attgcaattt ttagttcact atctgcaagt
     4441 gctgcctcaa gtatcctcat actgctgttc attaatcggc gatacagttt acggttagtt
     4501 atctttgctt atctgctttc gctcttattg atcatcggta gccgattgat ctggcgtatc
     4561 tacatcgaaa caaaaaatat gagatacgta tcagcagatt ctgctaaaaa tacattgatt
     4621 gttggtgctg gcgaaggcgg gcgtatttta tacaacagct ttcttggatc caaaacggct
     4681 caagatatcc acgttgtcgg gtttgtagat gatgatccaa ataaaagaaa tacgtatctt
     4741 tcaggaaaaa aagtattagg tgcattaaaa gatattccgg aattgattga aaaatatgac
     4801 attcaaatgg taacgatcgc tatcccttcc ttatcaagaa aaaaattacg acgaatcttc
     4861 gagttagtcg aatccgctcg tgtgaaagtc aacacgatgc cttctataga agaacttgct
     4921 tcagggaaaa ttagcgtatc aaaattaaaa acaattgacg tagtggattt actgggaaga
     4981 gatgaggtaa agctggatat tgaatccatc aaagatcaga tcacagacaa agtcattctt
     5041 gtcaccggcg caggaggatc gatcggttca gaaatctgtc ggcaaatcat tcaattcaat
     5101 cctgcaaagc tattgctttt aggacatggg gagaactcga tctacttgat tgaccgtgag
     5161 ttacgcacgc atcatcaaaa ttgtcctaca gaaatcgtac cgatcatcgc agatatccaa
     5221 gatcgcgaga aaatcaatga gatcatggaa caatatcatc cagatatcgt ctaccatgca
     5281 gctgctcata aacatgtacc actgatggaa tataatccaa aagaagcagt caaaaacaat
     5341 attttcggta caaaaaatgt agcagaagca gctaaagcag caaaagtgaa aaacttcgtc
     5401 atggtatcga cagataaagc taacaatcct ccaaatgtca tgggttcaac aaaacgaatc
     5461 gctgaaatga ttgtgactgg attgaatgaa gaaggctgta cgaaattctc agctgtcaga
     5521 tttgggaatg tccttggttc tcgcggtagt gtgattccag tattcagaga acaaattgct
     5581 caaggtggtc caatcactgt aacagacttt cgtatgactc gatactttat gacgattcct
     5641 gaagctagtc gtttagttat tcaatctggc gcattagcaa aaggtggcga aatttttatt
     5701 ctagatatga gtgaaccagt gaagattgta gacctagcga aaaacatgat ccgattgagc
     5761 gggtatagcg aagacgaaat cgaaatcatt gaaacaggta tccgtccagg ggaaaaacta
     5821 tatgaagaac tattgttgga taaggaaaga aatgatgaag cagtttatga gaaaatcttt
     5881 gtaggaaaca tcaaaggtta ctcaatacaa aaagtgatgg attttgtcaa gagcctgccg
     5941 caagacgatg aacaattggc taaagacatt gtcacttttg caaatgcttc gaatagatag
     6001 gagattaaaa attgaatatt ttaatattaa gttgtggacg tcgttgtgaa ctagtgaatg
     6061 catttaaaac agcattaaac aataatgaaa tggaaggaaa aatccttgga gcagattgct
     6121 ctgaactagc acccgcacta tatatgtgtg acgaaaaaat agtattacct aaagtttcag
     6181 aaagtaatta tattgaggaa ttaataaaag taataaagtt ttttgaaatt aaattaattg
     6241 ttcctactat tgatactgaa ttatcaacat tatcaagaaa taaaaaatat attgaaaatg
     6301 aaacagactc agttgtatta gtttcttcag aaaaagtcat cgacatttgt gagaacaaaa
     6361 ttttaacttc tgcttttttt gaacaaaatg gttttaaaac tcctgaaatt ttaaactctt
     6421 ctgaaattac aaaatttcct gtatttataa aacctctgaa tggtagttca tctgttaaca
     6481 catttattgt aaataatgaa aaagaattgt tgttttttag tgaatatata gataatcctc
     6541 ttattcaaga gtatatttta ggtgaagaat atactataga tgtttgctta aactttgatt
     6601 cgacaccagt aagtattgtt cctagaaaaa gaatagcaac tagaggtggg gaaatactga
     6661 agggtcagat tattaaagat agagaactaa ttgagactac gaaaaagatg ttggaaaaat
     6721 taaatgcaat cggacatatt actattcaat gtataaaaaa cgaaaaggga atattttatt
     6781 tagaaataaa tgcaagatac ggtggaggag cccccattag cattaaatca ggagctaatt
     6841 cccctgaata tattataaag atgatagatt caaaaaaaaa tttgagatac agagaaaatt
     6901 atttagataa aatgatagca ctgagatatg atcaagcgat ttatttagat gaaaaaggaa
     6961 atgtatataa tgattaaagc ggtgatcttt gatttagatg acactcttgt gtctgaatat
     7021 gattatgtaa aaagtggata caaatgtgta gctagaagat tagcagtgca aaaaattttc
     7081 ccggctactt ttgacgaaat atatagagtc cttttagatc tttttgctga agatagtaaa
     7141 aatgtattta atcgtctata tgactatttt gaaattcctt atagtaaaaa agaaattaaa
     7201 gaactggtaa atgtatatcg agaacacaaa ccagacataa attttttaga aaatgcagat
     7261 actttattaa cggaattaag aagtagagga tacaagctgg ggattattac agatgggtat
     7321 gctataaccc aacgaaacaa attggatgct ttgaaagtag actatttggt agattatatt
     7381 tgtattactg acgaattagg ccgtgaattg tggaaaccac accctatctc atatctttta
     7441 ttgttagaaa agtttaattt aaaggcacaa gagtgtatat atattggcga taatgagttg
     7501 aaagatttta taactgccaa atcaatagga atgcaaacaa ttaaaataga aagagtaaat
     7561 ggtatttaca gagaaagcag tttgaagttc aaaagatttt accaagctga taaaaaaata
     7621 cgttcgttat gggagataaa aaattttttg ggagtgattt catgaaaagt aaaagaattc
     7681 tattagcttc tccacatatg agtgaagaag gatatgaaaa agagtatgta aaagaagcat
     7741 ttgatacaaa ttgggttgct cctttaggtg cgaatgtgaa tggatttgag aaagaattag
     7801 cagaatacgt gggagctagt catgctgccg cattatcttc tggaacagca gctatacatt
     7861 tagctttgaa agcggctggg gtcggtaaag atgacatagt gatttgtcag tccttgacgt
     7921 tctcagctac tgctaatcca attctctatc aaggagctat acctgtattt gttgatagtg
     7981 attacgaaac ttggaatatg aaacctgaac atttgcgaac agcactagaa aaatatccta
     8041 acacaaaggc tgtattagta gtacatttgt acggtttatc agctaattta gacgaaatta
     8101 ctaaaatatg caaagaatac gatgttactc taattgaaga tgctgcagaa tcattaggaa
     8161 caacatataa aggaaaatat actggtacat ttggcgacta tggaatttat tcttttaatg
     8221 gaaataagat aatcacaact tcaggtggcg gaatgcttgt atccaatgac aaagaaaagg
     8281 tggaaaaagt gagattttgg gctacgcaat ctcgtgagaa ggcacgccat tatcaacaca
     8341 atgaaattgg ctataattat cgaatgagca atatcgttgc tggtatcggt cgaggacaat
     8401 tgaaagtatt aaatgaaaga attgagaaaa aacgatatat tcatagtttt tataaaaaag
     8461 aattgtctaa attgtcaaat atacaattca tgccagaaaa taattggaat gaaccgaatt
     8521 attggttaag tgtcataaca ataaagggaa taaatgcgaa tcatcttatt gatgagttag
     8581 acaaaaataa tatagaagcc cgcccagtat ggaaacctat gcatttacaa cctgttttta
     8641 aaaattatga ttatattggc gatgatgtag cagaaacttt atttgactta ggagtatgtt
     8701 taccatcaga tacaaagatg acagatgaag atttaaaata tgtagtatct acgattaaaa
     8761 gagtgatcaa tgatgcgtaa aaaaactttc tatcagcttt ttgggaaaag aattttagat
     8821 atcctattgt caggaattgc tctcatcgtt ttatcgccga taatcttaat tgtaggtttt
     8881 ttagtaagaa ttaaacttgg ttctccaatt atcttcaaac aagaacgacc aggaaaaagt
     8941 gaaaaaattt tttccatgta taaatttcgt acaatgactg acgaaagaga ccacaatgga
     9001 gaatatttac ctgatgaaat tcgactaact aaatttggga aaatgcttag agcaacaagt
     9061 ctggatgagc tacccgaact ttggaatatt ttgaaaggtg atatgtcgat cgtaggacct
     9121 cgtccattat tagtggagta tttgccacta tatagtgaga agcaacggaa aagacacaac
     9181 gtaagaccag gattaactgg actggctcag gtcaatggaa gaaatgctat tagttgggaa
     9241 gaaaagtttg atttagatgt ttattatgtt gataaaatta gtttctttaa tgatcttatt
     9301 attataattc agacatgtaa aaaagtaatc aagaaagaga atattaatac aatcaataac
     9361 aatatcccag aaaaatttaa agggagttaa atacagcagc ttaatgcaag ttttgtgact
     9421 tgcattatat ttaggtataa atcaaagcga gtatattaga attatataac atatgttaaa
     9481 aaaacgtata gctaataaaa gtatgatttt aaa
//
LOCUS       DAFLWZ010000094         9450 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000094 DAFLWZ010000000
VERSION     DAFLWZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.096"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(130..777)
                     /locus_tag="L1V38_002519"
     CDS             complement(130..777)
                     /locus_tag="L1V38_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBN1317021.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="L1V38_002520"
     CDS             complement(1056..1559)
                     /locus_tag="L1V38_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1317022.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="L1V38_002521"
     CDS             complement(1682..2446)
                     /locus_tag="L1V38_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBN1317023.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="L1V38_002522"
     CDS             2553..2828
                     /locus_tag="L1V38_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBN1317024.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="L1V38_002523"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="L1V38_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1317025.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1V38_002524"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1V38_002524"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1317026.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="L1V38_002525"
     CDS             complement(5605..6063)
                     /locus_tag="L1V38_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1317027.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="L1V38_002526"
     CDS             complement(6060..7523)
                     /locus_tag="L1V38_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1317028.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1V38_002527"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1V38_002527"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1317029.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="L1V38_002528"
     CDS             8598..9347
                     /locus_tag="L1V38_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1317030.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2809 a         2000 c         1640 g         3001 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat
//
LOCUS       DAFLWZ010000095         9302 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000095 DAFLWZ010000000
VERSION     DAFLWZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.097"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(33..701)
                     /locus_tag="L1V38_002529"
     CDS             complement(33..701)
                     /locus_tag="L1V38_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1317031.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            835..1122
                     /locus_tag="L1V38_002530"
     CDS             835..1122
                     /locus_tag="L1V38_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317032.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1538..3076
                     /locus_tag="L1V38_002531"
     CDS             1538..3076
                     /locus_tag="L1V38_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBN1317033.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3073..4038
                     /locus_tag="L1V38_002532"
     CDS             3073..4038
                     /locus_tag="L1V38_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1317034.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4025..5347
                     /locus_tag="L1V38_002533"
     CDS             4025..5347
                     /locus_tag="L1V38_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1317035.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5410..5514
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5588..6331
                     /locus_tag="L1V38_002534"
     CDS             5588..6331
                     /locus_tag="L1V38_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317036.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6346..7338
                     /locus_tag="L1V38_002535"
     CDS             6346..7338
                     /locus_tag="L1V38_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1317037.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7350..8087
                     /locus_tag="L1V38_002536"
     CDS             7350..8087
                     /locus_tag="L1V38_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1317038.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8077..8799
                     /locus_tag="L1V38_002537"
     CDS             8077..8799
                     /locus_tag="L1V38_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1317039.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8883..>9302)
                     /locus_tag="L1V38_002538"
     CDS             complement(8883..>9302)
                     /locus_tag="L1V38_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1317040.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3048 a         1603 c         1966 g         2685 t
ORIGIN      
        1 tgtaaattaa ataaagtagt gaaaaataag aatcagtgct ctaactgttc aagaggatca
       61 agtggttcaa atgtttctgt agtctgtttt gcttccaatt ggggcaaaac agatccaatt
      121 tccagatact tcactttatt caatgtataa gatagaatag aacagctaag taatgtatac
      181 agaaaatgtg tgagatccaa ataaagcaag gagacaacta aaataccaaa agtaatcaag
      241 aaaagacttt tgccaatctt aatatgaaaa tatttttcaa tggcttgata aatgatatct
      301 gttccgcctg tgcttccgcc gaatcgaaag acgagaccgc aaccaatgcc agaaagaata
      361 cctgtcatca aactattgat cagtagacta tctacagcaa aatgtatatg aaggctctcc
      421 cataaatgta aaaagaaaac tagcgcaaat gttccgacga tcgtccggag aaaagcgtgt
      481 tttccaaaaa gaaacaatga gataagcaat aaaggtaaat taaaaagcag tgaagtgaca
      541 gaaggagcga atccaaaaag attatgcaaa agcaaagcaa taccagtaac cccaccatct
      601 gccagcttag atggaatatt gattcctgtc acagctaatc cgtagattcc tgcgcctaaa
      661 atgattccgc acaattctgt aaataaattt aattttttca tttctagcct cttttctttt
      721 gaaaattttc agcaacttct ttattatact gacttatact cttacttcaa gaggaaaatg
      781 aaaaaaaatt atttttggct gtttcttttt atttatcaaa taaggagtgg aaaaatgcga
      841 gcagcagact tattgacaat tcttacaaaa tcacccaaaa aaacagagta tcaaggagtt
      901 tttttggctc aagaacaaaa actggtgcct gtgacaatgg tccagataaa taaagcaaat
      961 caatttatct ttttatttga acacggcaaa gcaccacttg ctatgaaaga catctttctt
     1021 tttttgatga agaaccgtga gaaagctgtt tattatcagt caaaagaaga actcattcct
     1081 ctttatggag tgaaagagat agaaaataaa gtggtgatat aagtaaaaat aagaaaacaa
     1141 gacgtttatg atgtcaaaac aaccattttt tacatttttg gcaaaaaagt gtcatgatac
     1201 agtataatat tcgttgaaca ggccaataaa ggtgttctcc cccacgagat ttctacttta
     1261 ttggctgttt ctttttatta aaataaaagt tgtgtgtgta aaaaagatat agctgattcc
     1321 aagtgacaat ttcgtataga tttttatggt attcgtagtg aaaaaacgag aaccaaaaag
     1381 ttgatccgac tttgttgctt ggattctttt tttgtcagca tatttagagg tatttttttc
     1441 ttttttttgt tcgtgctgta aggttaaggc aagacaagtt agttgggaaa aaggaaagaa
     1501 atgtttatac ttaaagaata acagaaagga aggtcgcatg aataatttta tacaaacatt
     1561 aagtgaaaga aaaggcgagt tgctggaagc tgcatttcaa catctgtcca tttctctcat
     1621 ttctttgctg attgcagcac tgattgctat tcctttagcg atttgggcag ccaatcataa
     1681 aaaaatggca gaagtcttat tgcagatcac gggtgtgctc caaacgattc cttcacttgc
     1741 cttattaggt ttacttatcc catttgtagg gatcggaact gttccagcat tgattgcact
     1801 tgttatttac gctttgcttc cgattttcca aaacacgtat attggtctag ctgaaattga
     1861 cccgtctatt gaagaagcag cggtagcatt tggtatgtcc agaatgagac gcttgctgaa
     1921 agtagagctt cccatcgcat tacctgtcat tatctcaggt atccgaactg ccttagtttt
     1981 aatcatcggt acggctactt tggcagcatt gatcggagca ggtggattag ggacatttat
     2041 tttgttaggt attgaccgaa atacacctgt tttgacattg attggtgcga tcagttctgc
     2101 cttgcttgca attatattca gcggactgat tcgctggttg cagcataaga aacctcgata
     2161 ttccatcatt actttagcag cagtggtgtg tttatttggc ggcgtttctt tatatcagtc
     2221 tgccttgttt aaaaatgaaa ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat
     2281 cctgatccaa atgtataaag aattgattga agacaacaca aaaacagaag ttgaattaaa
     2341 accgaatttt ggcaagacga gttttttgtt caatgcactg gatcaaggtc aaatcgatat
     2401 ctatcctgag ttcacaggta ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa
     2461 aagtgctgat ttgacaaaag aaaaaacata tgacgaagca gaagaattat tgaataagca
     2521 attcgatatg acattattaa aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa
     2581 gagatctttt gcgaacgaac atcaacttaa aaagatttcc gatttggcag ctatctctga
     2641 tcagatcaaa gcgggattca cactggaatt tattgatcgt tcagatggat ataaaggaat
     2701 ccaagaagca tatggcttga atttttcaag tgtacaaagc atggagccaa gtttgcgtta
     2761 ccaagcaatc aataatggag atgtcaatat tgtggatgcc tattccacag atagccagct
     2821 caaggagtac gatctagtga ctctagaaga tgatcgaggg ttattcccag cttatcaagg
     2881 cgcaccgctg atgaaaaaag attttgctaa agaacatcct gaaatcgtta aagcactgaa
     2941 taaattaagc ggaaaaataa cagaggatca aatgattgat atgaattacc aagtcaatgt
     3001 cgaaaagaaa aagccgacag aagtagcacg aatcttcctg aaaaatgaag gattagtaaa
     3061 ggaggaagat cagtgactaa attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga
     3121 aagtatgtca tcgatgacct aaatctggca atcaaaaaag gagaaatctt tgttttggtt
     3181 ggtccttccg gtagtggaaa aacaactact ttgaaaatga tcaatggatt atctaaacca
     3241 tcagcaggag acatctactt caaaggaaaa tcgttaaatg aatataatct gcagaaaatg
     3301 cggtggaata tgggatatgt gctgcagcaa atcgctttgt tcccgaccat gacagtcaag
     3361 caaaatattg aagtcatccc tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt
     3421 gtagatgaac ttcttcaaaa agttggctta tctcctgata tttatcgaga tcgtatgcct
     3481 agagagttgt ctggaggaga acagcaacgg atcgggatca tccgagctat tgctgcaagc
     3541 ccagatgtga ttttgatgga cgagccattt agcgcattag atccgatttc aagaaactca
     3601 ttacaagaat tggttttgtc cttacacgaa gaattgggca cgaccatcgt tttcgttacg
     3661 cacaatatgg aagaagcaat caagctaggt gatcgtattg catttatgaa ggatggagaa
     3721 attatccaat gtgacacacc agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg
     3781 catttctttg atgaaccgaa acagacgaaa gagtggcgag tagaagattt agtcgtcaat
     3841 ggatatttct taaatgaaat accagaaaat gctcgtcaac aagtttgctt tgatacgcct
     3901 atgaaagaag tatattcgct tctttcggtg tatccaagca ttgtgatagt agaaaagcaa
     3961 agaagtattg ggtcgctgac aagtaaagaa atctttgctt ttttaagtcg agaggaggaa
     4021 ggaaatgaaa acatatgatg caatcatcat cggttcaggt gtgagcggct taagtgctgc
     4081 ttatggattg aaagaagcag gtaaaacagt actagtggtc gaagaagatc tatggggcgg
     4141 gacttgtcct aaccgtggat gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg
     4201 taatcgggta aaacaattga gtggaaaagg ttttaacgag atcccaactg ccaactggga
     4261 agaacttcaa aaattcaaac gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca
     4321 attagcagaa gctgaaatcg atcatctttc aggaaccgct cgttttttgg atgattcatc
     4381 tattgaagtc aacgaagaag tcttccatgc ggattactta gttttggcaa ccgggcaaag
     4441 acctacgatc ttaccagtgg agggaaagga atacttgaaa actagtgcag actttttatc
     4501 attgcctgta ctgcctaaag aaatcatttt tatcggtggt ggttatattg cttttgagct
     4561 agctacgatt gccaatgctg cagggagcaa agtaaccatt gtccatcata atcaacggcc
     4621 attaaaagaa tttgaggcgt ctttggtaga ggaagccgtc catcaaatgg aagcatctgg
     4681 cattcagttt gcttttggtg ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg
     4741 tttagtcgga aaagagacgg aattagtagc agatatgatt ttttgtgcga ctgggagaca
     4801 gccgaataca gaatctttag cacttgagca agcgaatatc gtctttgata aacacggaat
     4861 tgcagtcaat gattatctgc aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt
     4921 ttcaaggaaa accccaaaat tgacaccagt cgccactttt gaaggaaatt atgtagctaa
     4981 gcggataacg gatgcaacaa gcgaacctat caaatatccg attataccta cgatcgtcta
     5041 cgccagtcct aaacttgctg aagtaggagt tacaaaaagt cacgcctctt cgtcagatca
     5101 agtggtagag atggatctta ccagttggtt cacctatcat cgtgtcaatg aaccagttgc
     5161 taaggctgaa ttgacctttg accagcaaaa ttatttgatt ggtgctgcag tgattagcga
     5221 gcaagcagac gaattgatcg atgatttgac actcgtcatc aatcaaaaat tgactaaaaa
     5281 agagttggat agctatatca tggggtatcc gacattggca agtgatctct cctatttatt
     5341 gaaataatca gcatgataac taaagcgctt gttgcttttt ccttcttgtg ctacacttta
     5401 aaaaatgaat acctgtttct ggggatgtcg tagacgacat gagagtaagt tgtgaactta
     5461 gacccattga acctgtcagt taatactggt gaagggagaa acatagcaga cgcttgaagc
     5521 gggttactat gtcgtgccca tttcaagcgt tttttgttat tcatattaga agaaaggagg
     5581 taacaaaatg aagaaaaatc tttatccagc agtcagtatg gcattcattt taattatttg
     5641 gcagattgtt gtcatagttt ggaaaatacc tgcctttatt ttacccggac ctgctgctgt
     5701 attttctgca ttagcggcag atgcacaagt attactttcc cattctgtca cgacattaaa
     5761 tgaagcagtg cttggtttgg taatagctag cgttctttct tttattactg ccttggcaat
     5821 ggattattgg aagtttttag aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt
     5881 gccaatcatg gtgttagggc cattacttac cctatggttt ggtttcggta tgcttccaaa
     5941 agtgatcctt gttgtcttga taagctattt tccgatcgta gtttcttttt cggatacatt
     6001 gaggaaagta tcaaaagagc aaatcatctt tttgaaaacg atgggggcag atacagggaa
     6061 gatttatcga atatataaaa taccagcggg tttatccggc ttcttttccg gtttaaaagt
     6121 ggctgctact tattgtgtca gcggagcagt cgttggagaa tggctaagcg ctcaagcagg
     6181 cttagggtat tacatgatac gcgtaaaaaa cagctaccag atcgataaag tttttgctgc
     6241 gatcatttgt gtcattctat tgagtttatt gctgaatggc gcttgttcat tattgaaaaa
     6301 agggtattat cgtatgcttt atatttttta agagaagggg atcaaatgaa aaaattatgg
     6361 cttttattac cgctactgtt gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc
     6421 aaacaagaaa taaaggattt gaaaaaagtg acacttgttt tggattatgt accgaatact
     6481 aatcatactg gcatctacct agcaaaagaa aaaggctatt ataaagaggc tggtttaaat
     6541 gtccaaatca tcgaaccagg agataattcg acaagtattg gtctagtagg tgcggacaaa
     6601 gcacaatttg gtgtaagtta tcaagaagat gtcacttatg ctcacgcaga tggacagaat
     6661 ataccagtca aagcaattgc tacagtgatc aaacataata cttctggatt cgccacccta
     6721 tcagacagta acatccattc accaaaagat tttgaaggaa aaacatatgc aggttggcaa
     6781 agtccaagtg aagaagctgt cttaaaagct gtgatggaaa aagacggcgg ggacttttca
     6841 aaactgacaa tggtaggaag caatggagaa gggccagaaa gcttaggaaa atcctcagat
     6901 atccaatggt actttgaagg ttgggatatg atcaaagcaa aagaagcggg tattgaacta
     6961 aactatatcc cattgaaaga attagatgaa cggttagatt actatactcc ggtaattatt
     7021 acgaatgatc aactgatcaa aagtgatcca gaattggtac agtcttttat ggatgccacg
     7081 aaaaaaggct atcaggaagc tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa
     7141 tatgcaaaag aaaatgatcg gacgttttta gaagaatcac aagcattctt gtcaaaaaat
     7201 tatacggatg atcctgagaa ttggggattg atggaagaaa aagtttggcg caattataca
     7261 gcttttatgc aggaaaacgg attgatcaag caagatgtac cttcgcaaga actattcact
     7321 aatcagttta taaaatagga gtgatagata tgtcaatcca aatcagccac ttgaatgtag
     7381 tcattgaaaa cctgaaaata ttagaagaca tccatttcac tatccctaaa gataccttta
     7441 catcgattgt cgcgccaagc ggagccggta agtcaacatt gctgaaaact ttaacaggag
     7501 tccagcctat gacttctgga acgatcaaag tagacgatca aaaagtaact ggtctccata
     7561 cagcatttag ttatatgccg caagaagata tgttacttcc ttggctgagc gtctatcaaa
     7621 acgttacgtt atatcaaaaa atcaatcatc taacaatcaa tgaagaacaa gtaagggatt
     7681 atctggatat ctttgggtta aacggctatg aacatttttt gccggaacaa ttatctggcg
     7741 ggatgaagca gcgaacggcc ttgttacgaa caatcatgaa tccttcttct tacttgcttc
     7801 ttgatgaacc atttggagcg ttagatgcta tgaccagagg gcagatgcaa gactggatgt
     7861 tgaagctgcc taaaaaagca aagcggacta ctttacttgt gacgcatgat atcgaagaag
     7921 caatttattt atcagacagg attcttgtgc tttccgcccg tccggcacat gtgattgctg
     7981 agattcaagt gcctgaaaaa cgacggtcac gtgaatggct actgcagcaa tcagagttga
     8041 agcaaacgat ttatcagtta ttggcaggtg aattagatgt taagtgatgc tcattgtcat
     8101 ttagatggga gtcagagttt agcactcctt cagcaggaac acacgatttt gacgatcatc
     8161 aattgtgatt cgccagaaga atggaaggaa aacagacagc ttgcagcaag taagactcaa
     8221 gccttaagtt acggtatcca tccttggaaa gcagatagct atacgtttga acaagttgag
     8281 ccttttttga aaaaagcaag gatcatcggt gaaatagggt tagataatat ttggacgaat
     8341 gtaccgatga ctacacaaaa aaaagtattt gagcgacagc ttgcttttgc agccataaat
     8401 gagaaacctg ttgtactgca cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa
     8461 gcttacccta atcactattt gatccattgg tattcttctt tggactatca acaagactat
     8521 attgatttag gctgttattt cagcattggt cttgatttga aaaagaatcc agcagtctgg
     8581 caactagcta aagcagtccc aatcgaccac ttacttattg aaacggatgg actacatgca
     8641 gcagagtggg ctttaggggg gattttttca gaaaaagatt atgtctcact gcttgaagaa
     8701 cagttaaaga caatcgctga gatcaaagag ctatcagttg aagaagttaa aaaaaatact
     8761 tatcaaaact tggaacgttt cattagatta ggtaaataaa aaagagatgt gacacaacta
     8821 gtgtcgcacc tctttttggc tttctttgta taaaagtaaa ctgtttgatt aataaatgaa
     8881 tcttagtacc aaccgtttgc ttcccagaat gctttcgccg cttcccaaga accataacgt
     8941 gaagtaacat attgttctgc tactctttct tggtttgcag cagagtagtc accatttaag
     9001 taagaagaat ctaattggta acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg
     9061 cttgattctt tttgtgcgat ccattctttt gcagagcttg tgcttgctgg agtagcagca
     9121 gtttctgtta cagcaggagc aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt
     9181 tgaaccgttt cttgtacaac aggttgttca gcttggactg gtgcttcttg aacggctgct
     9241 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
     9301 ta
//
LOCUS       DAFLWZ010000096         9233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000096 DAFLWZ010000000
VERSION     DAFLWZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.098"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            32..865
                     /locus_tag="L1V38_002539"
                     /pseudo
     CDS             32..865
                     /locus_tag="L1V38_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            926..2074
                     /gene="dgoD"
                     /locus_tag="L1V38_002540"
                     /pseudo
     CDS             926..2074
                     /gene="dgoD"
                     /locus_tag="L1V38_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
     gene            2083..3078
                     /locus_tag="L1V38_002541"
     CDS             2083..3078
                     /locus_tag="L1V38_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HBN1317041.1"
                     /translation="MIKDIITIDVGTTNTRVSLWRDEELQEVFVYSQGVQKASLAGNN
                     DTVKKILECSIKKLFKKYNILAEKTVIIASGMITSAFGLVEIPHLNAPVGIQELAISM
                     KQFSFPEVCPQPIWFIPGVKTQCQDKSRLSSIQYDVMRGEETEAMAVFSLLKPTISDE
                     HIFVMPGTHTKFIKLDKNGRIVKSKTATTGEILSLLTKKSLIATDVHHRFYDELDESY
                     LLSGFHSARSNGIGSAVFDVRILGQTHNASRNQRANYLLGAVLSSDIQLLENFLEPNE
                     TVVLTGKKELREAIHVILNDLDNFSHPIIIIEANDLAGRGALLAGKKRGLLRKEG"
     gene            3083..3709
                     /locus_tag="L1V38_002542"
     CDS             3083..3709
                     /locus_tag="L1V38_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HBN1317042.1"
                     /translation="MELENYPKATAILRGYTYEEAMLVIRVLSEFKHFIGVEVTTNNS
                     DHLKIIHDGKNRFGDKISIGVGTVVTVEQAEEAIEAGAEFMLGPQKFNDKIFKLAKRK
                     GVLTIPGAMSPTEIFKMFEMGADIVKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQ
                     TNAQNYLNNGASYVGIGSKFFEKSAVHQLNYERLMELAESFIDSLRVE"
     gene            complement(4103..5110)
                     /locus_tag="L1V38_002543"
     CDS             complement(4103..5110)
                     /locus_tag="L1V38_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1317043.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLIVRKSFIPKEE
                     V"
     gene            5577..6983
                     /gene="lacG"
                     /locus_tag="L1V38_002544"
     CDS             5577..6983
                     /gene="lacG"
                     /locus_tag="L1V38_002544"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1317044.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            7006..7329
                     /locus_tag="L1V38_002545"
     CDS             7006..7329
                     /locus_tag="L1V38_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1317045.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVRKGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            7340..9022
                     /locus_tag="L1V38_002546"
     CDS             7340..9022
                     /locus_tag="L1V38_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1317046.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVAATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFG
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
BASE COUNT         2966 a         1398 c         1964 g         2905 t
ORIGIN      
        1 gaaagttttg tctcgcttaa tttgacaaat aataaaatca aaacagctga gaacgattgg
       61 taaaacttcg gttattcctt gtatttttgc agtgaatgaa ccactattat ttggaacacc
      121 aatgatttta aatccatata tgctaatacc atttgtggtg gcgccaatcg taaatgcatg
      181 gatctgtaaa ttttttgtgg acaatttgat gatgaatgga tttatctacg tacttccttg
      241 ggcaacacct gcgccaatcg gaattttctt agatactaat ttccagctga tatcaatcgt
      301 attgatcgtg ttgttgctaa cattggatgc tttcatctat atgccatttt tgaaagctta
      361 tgacaaagta ttgctaaaac aagaagcagc acgtactgaa ggtgaggcta tttctggtgg
      421 gatagtagca gagaaaccta ttgaggaaat gaaatcagct gatcctgacc cagagattag
      481 cttacaaata aacaaacttt cagataggga aaattcttta aaagtattag ttttatgtgc
      541 aggaggaggg accagtgaac aactagctaa tgcgttgaaa attggagcgg aggaaacgaa
      601 attcaattta gtttcaaaag ctgcagctta tgggaatcac tattcattat tgccgaatta
      661 cgatgtggtt gttttagccc ctcaaattaa gtctttctac aaagatataa aacaagacac
      721 agataaacat ggcattttat tgattccgac aaaaggtttt gaatatattg aattgacgag
      781 ggaacctgca ggggctatta aattcattac ggaaaaatta acagattcaa aattgaagga
      841 cgagctagcg tcgtatcttt cataatggaa tcattatcga tcaattgtca gattacgaaa
      901 atttcaaaag atagaaggag ttcaaatgaa gattacggga tataaaacgt atatggtgcc
      961 tcctagatgg ctattcttaa aaatcgaaac ggatgaaggt attgccggtt ggggcgaacc
     1021 cgttattgaa ggaaaagcgg caagtgtcga aacagcagtt catgagttta tggatcagtt
     1081 gctaggtgat gatccatctg ctattgaagg ctgatggtca aaaatgtacc gcagcagttt
     1141 ttaccgaggt ggtcccatat tgatgagtgc tattgcgggt attgaccaag cgctttggga
     1201 tatcaaaggg aaaacaatgg gacagccggt ctttcaatta ctgggtggtg cagtccgaaa
     1261 taaaatcaaa gtgtattctt gggtaggagg tgatcgtcct cacgatgtag gggcagcggc
     1321 actagaaaga aaaaattcag gattcaaagc aattaaaatg aatgcaacag aagaaatgca
     1381 gattatagac agctatgaaa aaatcgatga agtagtgcat cgcattgagg cggtccggga
     1441 tgcttgtggt ccgtatttcg gtatagcagt tgactttcat ggtcgaatcc acaaaccgat
     1501 ggcaaaagtg ttagcgaaag ctatagcacg ctttaatctg ttgttcattg aagaaccggt
     1561 attgtcagaa aacaataaag cactaagtgc gattacacaa ctggtggaga ccccaattgc
     1621 gactggcgaa cggatgttta gccgctggga ttttaaaaat attttagaga gcaacaatgt
     1681 tgatattatt caaccggatt tatcacatgc tggagggatt actgagtgta aaaagatcgc
     1741 aaacatggca gaagcgtatg atgttgctgt agccttccat tgtccgctag gcccgatcgc
     1801 tttagctgcg tgtctgcagc tagatgctgt tgttcaaaat gcatttattc aagaacaaag
     1861 tcttggaatc cattacaatg atggcaatga tctgatggac tacattaaga atccagaaat
     1921 tttcgagtat gaagacggtt atgtaaaaat cccacagtta ccaggattgg gtgttatcgt
     1981 ggatgaggag ttggtgattg aaaaatcaaa aatccctaat aattggcata accccgtttg
     2041 gcgacatgaa gacggaagta tcgcggagtg gtagatgaat atatgataaa agatattatt
     2101 actattgatg taggaacaac aaatactaga gttagcttgt ggcgagatga agaattacag
     2161 gaagtttttg tctattcaca aggtgttcag aaagcatcat tggcggggaa taatgatacg
     2221 gtgaaaaaaa ttttggagtg ttcaatcaaa aaattgttca aaaaatataa tattttggcg
     2281 gagaaaacag tgattatcgc ttcaggaatg ataacttctg cttttggact tgttgagatt
     2341 cctcatttga atgcaccagt aggaattcaa gaattagcaa tatcgatgaa gcaattttca
     2401 tttcccgagg tttgcccgca gcctatctgg ttcattcctg gtgtaaaaac tcaatgtcaa
     2461 gacaagtcac ggctttcttc gattcaatat gatgtgatgc ggggagaaga aacagaggcg
     2521 atggcagtat tttcattgct gaaaccgacg atttctgatg agcatatctt tgtaatgcct
     2581 ggaacacata ccaagtttat caaactggat aagaacggta ggattgttaa atcaaaaact
     2641 gctaccacag gggagatact ttcattattg accaagaaat cgttgatagc tacagatgtt
     2701 catcatcgtt tctatgatga attagatgag tcatatttgt tatcaggatt tcattctgct
     2761 aggagtaacg gtattggcag tgctgtattt gatgtacgca tattggggca aactcataat
     2821 gcttcgcgga atcagcgagc aaattatttg ttgggggccg tactttcttc ggatatccaa
     2881 ctattagaaa attttttaga acccaatgaa acagtagtac tgactggcaa aaaggagctt
     2941 agagaggcga tacatgtcat tctcaatgac ttagataatt ttagccatcc tatcataatc
     3001 attgaagcta acgatttagc tggtcgaggt gcattattgg ctggaaaaaa aaggggattg
     3061 ttaagaaaag agggataaat taatggaatt ggaaaattac ccaaaagcga ccgctatcct
     3121 gcgtggatat acttatgaag aggcaatgct agttattcgt gttctaagtg agtttaagca
     3181 ttttatagga gtcgaagtta caacaaataa tagtgaccac ttaaaaatta tccatgatgg
     3241 aaaaaataga tttggggata aaatttcgat tggtgttgga acagtcgtaa ctgtcgaaca
     3301 agcagaggaa gcaatagaag cgggtgctga gtttatgtta ggcccgcaaa aatttaatga
     3361 caaaattttt aaactagcta aaagaaaggg tgttctaaca attcctgggg ccatgtcgcc
     3421 cacagagata ttcaaaatgt ttgagatggg tgctgatatt gttaaggtgt tccccgccaa
     3481 ctgtcttgga ccggaatatt tcaatcaagt gcaagcccct ttaggaagtt tacctttgat
     3541 ggctgtagga ggggtagatc agactaatgc acaaaactat ttgaacaatg gagcctctta
     3601 tgtaggaatt ggttcaaaat tttttgaaaa aagtgctgtt caccaactaa attacgagag
     3661 gctaatggag ttggctgaat cttttataga tagtttaaga gttgaataga acccatttgc
     3721 ggaatacaac ttgttttata atatggcgtt atctgtataa aacatagtat cacagtgaat
     3781 gagattgaac tggtagattg atttttcgac cagttctttt tgcgcgctct gatgcttgat
     3841 atattcccaa cgagataaaa aatcccccaa gatactaaga tgaagcgttt atccaacctc
     3901 atacttagat aaaaaggagg aaatgttctg aatgataaac aaaaattagc gcgcacaatt
     3961 tggcgatgaa aaaatcatat tgtatttacg tcaaaatatc accatcaaat tatttatgga
     4021 aaacataata ggcataaacc cgattgctcg gctactatgt ggacacaatt atagttttaa
     4081 agataagttt caattactta ttttacacct cttctttagg gataaaactt ttcctaacga
     4141 tcaattttgc gccgattaat gttttctttg atatgtcccg cgaatatacc agttgatcac
     4201 ttaataaatc tacacaggtt ttagctatct cttcgatatc tatcttaaaa gttgtaagtg
     4261 gtggtgcaac gaattttgcg atgtcgtcat cattaatact tattactgcc atatctttag
     4321 ggatgttaat acccaattca tggcagccct gaagaacgcc ggcagctata gtgtcagatg
     4381 gtatgaaaca tgcctcgggc atatcttcat ttaactcagc tttcatttta agagttaatt
     4441 gatacccttc gtcaacagta aatgatcctt gggagaaaat atacttttca ttgagtagtc
     4501 cgctcttttc taaatgatat cggaaggcat attcacggct atcaatctct tctttacccg
     4561 tttctaggtt aaagaaattt cctccaataa atccaatttt tgtgaaacct tcattaataa
     4621 agtagttaat tgcttgtctg gccatttcgt ggaaatcagg ttctacagta tcgaagtgtt
     4681 caggtaatgg gtttattcct cggattaccc ccttataccc tttttgattt aagtagtaca
     4741 attccttttt tgtcaattgt cctattgcga taaatccagt aatatcgtca ggaatgcttt
     4801 ttacaccatc gtttttagag atgaaaatca aatctagatt agctttttta ctataatttt
     4861 tcaaatcatc tttgacatgt tgatagtaga catccttttt taactgttcc tctgagatcc
     4921 aaaaaagaat ggcaatcttg tacagagtag tcttaatttt tgtcagatca tatcctaaag
     4981 atttggctgt aacgattatt ttgtttttag tatcagatgt aatagagagt gactcatcac
     5041 ctttaaaaag tcttgatata gtagccgttg agtaaccaga tttttttgca atatctctaa
     5101 tagtaaccat tgttcatcct cctagggata taataatcct tttctttgtt aaagtaaatc
     5161 gaaactgctc ttttagtaac ttaaattact ttttctagca ggaaacgaaa ctctgatatc
     5221 agcagagagc ctaatccatt aacagagaag attgaatcga taatggatag ccacttggag
     5281 aatgattagt aggtgggatt gattttagtg ggaatcagtc cgttttcttg tttcgtgtaa
     5341 attaaattag taaaaagata aatttatttt acgaaaaaac gtttacaaaa cggtttttga
     5401 atggtatatt tattttacat caagggatat aagtgcttgt atatcgcaat aaaatagata
     5461 ttcgaggtcg gtttttcgtt gtgtaaaaaa atttacttat acatgttaaa attatgctga
     5521 ggtgatttat ggattattgg catattgatc aaactaattt tcaaggagag attaaaatga
     5581 attataaaac tttaccagaa gactttatta tgggaggagc tacggcagct tatcaagcag
     5641 aaggctctac aaaagaaggt ggaaaagggc aagtagcgtg ggatactttc cttgtagaaa
     5701 agggacgcta tactgctgat ccagctagtg atttttataa tcaatatcca gttgatgctg
     5761 aattatgcaa aaaatttaaa attgatagta ttaggatgtc tattgcatgg agccgtattt
     5821 ttccaaaagg ctatggggaa gtgaaccaaa caggagtgga atattatcat aaggtatttg
     5881 ctgaattgaa taagcatggt attattcctt ttgtaactct tcatcatttt gataccccta
     5941 aagaactatt tgataatgga gattttttaa atcgagaaaa tgttgaacat ttcgtaaact
     6001 atgcacagtt ctgtttcgat gaattttctg aggttcatta ttggagtaca tttaatgaga
     6061 tttatccagt tgcttcaaat caatatttga tcggatcgtt ccctccagaa gttcaatttg
     6121 atatagagaa gactgtaact tgtttacaca acatgatgta tgcgcacgca aagacagtaa
     6181 acatttttaa agatggtgga tataaagggg aaattggtgt tgttcactcg ctagagacaa
     6241 aatatccagc aagtgacaaa gaagaagata agcatgctgc gaaattagat gatgcgttat
     6301 caattaagtt cttattagat gctacttatt tagggtatta ctcagatgaa acaatggcac
     6361 atattaatga gattttagca gcaaatgggc aatctgcaga tattgattct aatgatttta
     6421 gagagatgaa aaaagcagca aatcgaaatg attttcttgg tatcaataac tatggtagcc
     6481 attgggttaa agagtacaaa ggagaaagca cacttcacta caacactacc ggagaaaaag
     6541 gtagccaagt ctattgcatt aaagggattg gcgagagaat cgtgcgtgag gatcttccga
     6601 aaaccgattg ggattggatc atttatccaa aagggttata tgatttactt gtacgaatcc
     6661 aagacgaata tccaaattat aataaaatat acattactga aaacgggcta gggtataagg
     6721 ataattttga agatgggatt attctagatg atgatcgaat cgattattta cgccagcatt
     6781 ttaatgcgat ttccgatgct atcaaaatgg gagttaatgt aaaggggtat ttcatttggt
     6841 cattaatgga tgttttctct tgggttaatg gatacactaa gcgttatgga ctattctatg
     6901 tagatttcga tacacaaaaa agatatccga aagagtctgc atattggtat aaatttgtta
     6961 gcgaaacaaa aacgataata taaaaatagt taggagggca aggaaatgga taggaaagaa
     7021 ttgcaattat taggatttga aattgttgct tatgcaggag atgccagaag ttcattatta
     7081 acagtgttga aggaagtgag aaaaggtaat tttgataatg ttgaacgatt attagcggat
     7141 gctgatgaaa atttaacctt agcgcataac tcacaaacga aatgtttagc tgaagaagcg
     7201 tcagggaacg aaatggaagt aggcgtaatt tttattcatg ggcaagacca tttaatgaca
     7261 acgattctat taagagaact tatcaatgat tttgttgaat tgtacaaaga aaaatttgct
     7321 aaagcatagg agaagaaaaa tgaatacgat tattaagcaa attgagaagg gaaaaccgtt
     7381 ttttgaaaaa atctcacgta atatttattt aggggcaatt cgcgatggct ttttaactgc
     7441 tatgccagct attctatttt caagtatttt tattatgatt gcggctgttc cagaagtatt
     7501 taacgtgacg ttaccagagg cattctcgac gtggctttgg aaagtttatg gttattcaat
     7561 gggattagtt ggtcttttgg ttgctgctac aacagctcga tgtttagcta attcaatgaa
     7621 ccgtcaatta tctgattcag gtaagcagat taatgaagtt tctgttatgt tagcgtcaat
     7681 ttgtggtttt gtaatgatgg cagctgatca aattgatggt gggatagcta ctgattattt
     7741 agggacaaag ggattattag cagctttcgt ttctgcgttt gttactgtaa atgtgtataa
     7801 attctgtgtt aaaagagatt tgacgatccg tatgccaaaa gaagttcccg gaacaatcac
     7861 acagatgttt agagatatta tccccttttc aattgcagta tttattgccg ttttgattga
     7921 tacgggagtt cgtcaatttt ttggaacatc atttgcagca ggtgtaattc aattattgca
     7981 gccattattt ggtgctgctg atggatatgt cggtattgca atcatttggg gagccatggc
     8041 aatgttctgg tttgttggtg ttcatggacc atcgattgtt gaaccagcga ttgctgcaat
     8101 tatttatgcg aacgtagaaa ctaactttga attatttaaa aacggtgcac aagcctcaaa
     8161 agtattaaca gttggtctag gaaactttgt tggaacgatg ggtggtactg gagcgacact
     8221 agttgttcct tttctgttca tgttgttcgc taaatcaaaa caattgaaag cagttggtaa
     8281 agcttcattt attccagttt cgtttgcggt aaatgaaccg ttactatttg ctactcctat
     8341 tattttgaat ccgtactttc taattccatt tttattagca ccaatcgcta acgtatggat
     8401 attcaaactt tttgtcgatg tcttggggat gaatagcttt atatccgtat tgccttgggc
     8461 gacgcccgca ccgattggct tggttttagg aaccgggttt agtgtgttgg cgattgtatt
     8521 agcggtagta ttgattgttg tcgatgcgat tatttattta ccttttgtta aggcctatga
     8581 ttctgaatta gtagaacaag agttaaaaaa cattgctgca gaagaagtaa aagaagaatt
     8641 ggtcgaagaa atccaagaag ttggtgcaac tgcggcagtt atagttgatg aagcaaaagc
     8701 atcggttggt gaaggaaagc gcgttttagt actttgtgct ggtgccggaa cgagtgcaat
     8761 gttggctaat gcattagaag agggcgcaaa agagacaggt gttaatcttt ctgctaaagc
     8821 aggagcttat ggttctcatt atgatatgat gaaaaatttt gatttaatcg ttctagcacc
     8881 tcaagtgaat tcctatttgg atgatctccg taaagatgca gacaaattag ggataaaagt
     8941 aattgcaact aaaggtgcag aatatatcaa tttaacacgt gatcctaaag gagcagttga
     9001 ttttgtattg aagcaatttt agagcttgct tagattaata aagcgctagc caacttagct
     9061 agcgttttat cttaaacaca atggtaagcg ctatcttttt ttgctgttta aatttcgggt
     9121 attctttttg aggacgtcga ttgtaaaatt aagctagaca actaaaaaga tcatttgtgc
     9181 tacactcaaa atagttccga ccaaagaatt aataaggagt gagtacaaat gac
//
LOCUS       DAFLWZ010000097         9133 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000097 DAFLWZ010000000
VERSION     DAFLWZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.099"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            21..251
                     /locus_tag="L1V38_002547"
     CDS             21..251
                     /locus_tag="L1V38_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBN1317047.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            348..1649
                     /gene="murA"
                     /locus_tag="L1V38_002548"
     CDS             348..1649
                     /gene="murA"
                     /locus_tag="L1V38_002548"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1317048.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1662..1838
                     /locus_tag="L1V38_002549"
     CDS             1662..1838
                     /locus_tag="L1V38_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1317049.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1973..2269
                     /gene="yidD"
                     /locus_tag="L1V38_002550"
     CDS             1973..2269
                     /gene="yidD"
                     /locus_tag="L1V38_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBN1317050.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2333..2800
                     /locus_tag="L1V38_002551"
     CDS             2333..2800
                     /locus_tag="L1V38_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1317051.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2885..3769
                     /locus_tag="L1V38_002552"
     CDS             2885..3769
                     /locus_tag="L1V38_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1317052.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            3883..4119
                     /locus_tag="L1V38_002553"
     CDS             3883..4119
                     /locus_tag="L1V38_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBN1317053.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4207..4287
                     /locus_tag="L1V38_002554"
     tRNA            4207..4287
                     /locus_tag="L1V38_002554"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4241..4243,aa:Tyr,seq:gta)
     gene            4294..4365
                     /locus_tag="L1V38_002555"
     tRNA            4294..4365
                     /locus_tag="L1V38_002555"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4326..4328,aa:Gln,seq:ttg)
     gene            4491..4661
                     /locus_tag="L1V38_002556"
     CDS             4491..4661
                     /locus_tag="L1V38_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317054.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            4881..5588
                     /locus_tag="L1V38_002557"
     CDS             4881..5588
                     /locus_tag="L1V38_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1317055.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5647..6291)
                     /locus_tag="L1V38_002558"
     CDS             complement(5647..6291)
                     /locus_tag="L1V38_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBN1317056.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            6418..6705
                     /locus_tag="L1V38_002559"
     CDS             6418..6705
                     /locus_tag="L1V38_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317057.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6813..7133
                     /locus_tag="L1V38_002560"
     CDS             6813..7133
                     /locus_tag="L1V38_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1317058.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            7451..8527
                     /locus_tag="L1V38_002561"
     CDS             7451..8527
                     /locus_tag="L1V38_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1317059.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            8524..9133
                     /locus_tag="L1V38_002562"
                     /pseudo
     CDS             8524..9133
                     /locus_tag="L1V38_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         3023 a         1514 c         1976 g         2620 t
ORIGIN      
        1 tcgttagaaa ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga
       61 gtcatttggc gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt
      121 ttttcagacc aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt
      181 tagggtacac tgcaagtaat tttttcttag aggttatcgc tttatgccga aatcttttcg
      241 ttagcctgta aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa
      301 gattttgagt aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca
      361 tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg
      421 ttttgcctat tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg
      481 ttccgattct ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg
      541 tagattttga tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg
      601 aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac
      661 ttgccagaaa tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac
      721 caatcgattt gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg
      781 gctatatcga agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta
      841 gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca
      901 ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg
      961 gcgctcaagt ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac
     1021 atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg
     1081 ctgcaatgac acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat
     1141 tgatttctaa attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg
     1201 tcatcggacc aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc
     1261 ctacagatat gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtgg
     1321 tgactgaaac agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg
     1381 ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg
     1441 cagaagtata tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag
     1501 caaatggaat cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc
     1561 atatcaaact acagcaatta ggtgcagacg tcgaacgtgt agacatggat caaacttctg
     1621 ctgaaaaaac agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata
     1681 tcttattaac tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg
     1741 ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc
     1801 caagtttgtg gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc
     1861 tagtcgatat gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt
     1921 gacgttagtc gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa
     1981 gatattgatt tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag
     2041 ctgccgttat tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc
     2101 gctaaaaggg acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg
     2161 cggtatcgat tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga
     2221 accagattat aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg
     2281 aaatttattg tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga
     2341 agaactaaac aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga
     2401 aaaagttcaa gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac
     2461 aataggtgta ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt
     2521 aaccccaacg tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa
     2581 gctttcacag ctagcttcaa accaaactcg gatcattata cgtactggca ctactagtag
     2641 cgctgcgtta cacctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta
     2701 ttttatccat cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt
     2761 gattttagca attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa
     2821 atgctttcaa atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat
     2881 ttttatggga atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga
     2941 tggcaaagag attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa
     3001 aacgcaatta tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg
     3061 aatcagctct cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat
     3121 tccttatatt catggattta atattttccg agatttggaa actctgtttc aactcccagt
     3181 aacgattgaa aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg
     3241 tgattatcaa gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac
     3301 gaaaggacaa ataaataaag gggcacatct ttacggtgga gaatttgggt tgatgttctt
     3361 agatggcgat aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg
     3421 tgaacgcaaa ggtctcgata aaaatgctta taccggaaaa gatgtctttg aattagcaga
     3481 aactggagat gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg
     3541 attattcagt attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggggtttc
     3601 tgcaaaagaa gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt
     3661 cgatctgcat gatttcgaac cgcagatttt attatgtgag tacagaaacg atgctaatct
     3721 tataggtgca gcagcaaact atctcgctgt acgtcaagga gagaattaag agctttagag
     3781 aaggtgcagc ttgcataaaa gaagagaatg aaatgaatag gagattttta cctaaggaat
     3841 gttttatttg ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat
     3901 aaagatattg aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa
     3961 gtcactcagt tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa
     4021 gaatatgaaa ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg
     4081 atagaaacag tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc
     4141 aataaagggt tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa
     4201 cctttcggag gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt
     4261 tcagtggttc gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag
     4321 ggactttgac tccctcatgc gttggttcga atccagctac cccagtatac cacaatcgta
     4381 agctctcgtt agttcgagag ctcttttttt ttgctttgct accttgttcc ttgaagattc
     4441 tgctgaatta agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga
     4501 aagaaaaagt agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca
     4561 atattgaagt gaatattccg aaaaaaggcg gaaaagcggt ccaggtaaaa tcaaaacgcc
     4621 caacgaatca tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata
     4681 agtcggcatt ttcatcgatt ttagggtctt ttgttatttt ctaggttgaa catatctaaa
     4741 aaattgtttc tgacaatagg agtagggaga acgatgtgtg tctaaatcct ctgttgatgg
     4801 atagaaacct ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa
     4861 cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc
     4921 aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa
     4981 gagaattagc agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact
     5041 tggcagatga aggaatctta gaaagaaaga tcggttcggg tacgtatgtt gcgcgagaaa
     5101 aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc
     5161 gagtaccgtc tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg
     5221 aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag
     5281 atgatgtccc tatttgtttt gaagttgcca gtgttccaca aaagctgatc gatggctaca
     5341 gcaaagcaga gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga
     5401 tcggtccagc gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt
     5461 tagaggtaaa acgaagagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg
     5521 gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg
     5581 aaaaataaaa aacaggtgat ccctgattcc ttattagaaa taaaagagaa tcagaatcac
     5641 ctgtttttat atatgatcag ttatcagttg ctcgtgataa gaaacagaac cctcttcaaa
     5701 ttggacttgt ccgttcagca gctcaatgat ggattcttta aagtggttag cacttttttc
     5761 atctacagca cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg
     5821 ttggagttca agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat
     5881 ctcctgttgc aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg
     5941 agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac
     6001 tactgcagct acattgatca gttgattttt tttgaggact tccaacatcg gtacgcccgc
     6061 cgttccactt ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat
     6121 gaaggcgctg cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaatt
     6181 ttttgcttgg tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat
     6241 ctcaatctca ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc
     6301 tctttttttc attttcttta ttcagtataa ataaagttct aggttgtttc aacactgtaa
     6361 cggttgcgca attgctgtag tatgcgataa taaagacaaa ggcaggtgga tctggggatg
     6421 caggaacgaa tgaaaaagta cgatgcaatt acgcattatt tgaagaacaa tggcggctct
     6481 caagtaacgt tgacctttac ccaatttgac gaactgctgt ttcccagtaa cggacttccc
     6541 aaaacagcaa gggaaagtac agattggtgg gcaaatgatt ataaacaccc tgaaaaaggt
     6601 gcctatggct ggataaatgc aggctatgaa gtagttgtca tcaatttgga caaagaatat
     6661 gtcgtgttca ataaattagt gaaatctagt tggctatttg attaaataaa ccgcgtttag
     6721 aaaacgttga caaatttctt tctttttata taataaagta acagacgcga agaaaacgtt
     6781 tgcgtagttt gttttaaaaa ggagagaaaa atatggctaa aaaaacaatc atgcttgtat
     6841 gttcggctgg tatgagcaca agtttactag taacaaaaat gcaaaaagct gctgaagcaa
     6901 aaggaatcga ctctgatatt ttcgctgtgt ccgcttctga cgcagataac aatcttgcaa
     6961 ataaagacgt ggatgtgttg ttattaggcc cacaagttcg ctttatgaaa gctgattttg
     7021 agaaacgtct ggaaccaaaa ggcattcctt tagatgtcat caatatggct gattatggta
     7081 tgatgaatgg cgaaaaagtg ttagatcaag caatcgcgct cataggtgaa taaatagaac
     7141 agtataacta tcgaacaagc gatccaaaaa atagatcgct tgttttttcg tatatttttt
     7201 tagggcgaat aatatgaatc atttttgggg tagaaggctt ctgacgagag atattaaagc
     7261 aatagactgt gaggaggtaa atttaccaaa ttatgagaag atcgcagcag tggaacgttt
     7321 gggcaactgg attctttgtc atcgctgtgg aatgaggacg tccgtcattg ttggacagct
     7381 tgcagattac ggttattttt gtacacattg tctatattta gggtgatgcg acactcaaca
     7441 agatttatat ttgtttgatc agcctgaagc aaaacctcga gaagtcgtct ttttttggac
     7501 aggacagctt actgaaaaac aaacggaaat cgcaaagaga atactttgcc attcagaaaa
     7561 aagacatcat cttatttggg ctgtaacagg tgcagggaaa acagagatgc tttatcctat
     7621 tttagtggaa actttaaaag ctggaggaag agtagcgatt tgtacaccgc gagtcgatgt
     7681 ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca gaagaaaaaa tcacgttgct
     7741 ccatgggaat acagcaacgg cttatacctt tacttctttt gttatctgta cgattcatca
     7801 gctataccgt ttttatcggt cctttgattt aatagtgatc gatgagatcg atgcgtttcc
     7861 ttataacggg gatgctgggc tagctcacgc tgtgcaaaca gcaatcagat caaacggccg
     7921 attcatctac ttaagtgcca cgcctgatga gaagttacta aaggaaatca agcagacatt
     7981 tgagctccac aaacttgcct tgcgctttca tcggcgcttg cttcctgaac ccgtgcttgt
     8041 tttcatgaat aattggcgac aaaaatgtgg aaacaaaaag aaaatcaact ctttggtgcg
     8101 gatcattcag caactaatca aagaaaaccg tatcctttta ttttgtccaa gtattacgat
     8161 gatgcatcgt ttaaaaatca cactgcaaga agcttttcca gaatatgaga taacagatgt
     8221 ttcttcacaa gacgatcaac gggcaaagaa agttcagaaa atgcgagaag caatatacga
     8281 gatactgtta accacaatga tcctagaaag aggagtcaca tttgaaagaa tctctgtcat
     8341 cgttttagga gcagatcatc cagtttttac taaatcctct ttggtgcaaa tcgcaggaag
     8401 agctgatcgt aaaggtcctt atacgaacag tcgagtctat tttttctatg aagaaaaaac
     8461 ttcagctatt cgaaaagcct gtcaggaaat caaagaaatg aacgaagaag ggaagcagat
     8521 gctgtgagat gtagttgctg cggtaaagac atcattcaaa atttaacatt cagcgagatc
     8581 atcggagtgt cgaaatctag acttcctcag acatgttcag tttgccgcgc acaattccat
     8641 ttattagaag caaaaggttg tgcaggttgt caaaaaccaa tccatttgaa atacgaggag
     8701 acgaaaaaga aagcaaatac tagtttcgtt tactgcaacg actgtcaaga atggaagaag
     8761 aaatatcctg catatgattt tcaacaccgc gcctttttta cgtacgatga aaagatgcag
     8821 gcttggatca atcggtacaa gtttatggga gatatccgat tagcagggac ttttgcatat
     8881 aaatggactc agataaaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
     8941 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
     9001 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
     9061 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
     9121 acaacataaa aaa
//
LOCUS       DAFLWZ010000098         8736 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000098 DAFLWZ010000000
VERSION     DAFLWZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.100"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            96..1103
                     /locus_tag="L1V38_002563"
     CDS             96..1103
                     /locus_tag="L1V38_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1317060.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1115..2119
                     /gene="neuB"
                     /locus_tag="L1V38_002564"
     CDS             1115..2119
                     /gene="neuB"
                     /locus_tag="L1V38_002564"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBN1317061.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2116..3264
                     /gene="neuC"
                     /locus_tag="L1V38_002565"
     CDS             2116..3264
                     /gene="neuC"
                     /locus_tag="L1V38_002565"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBN1317062.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3237..3914
                     /locus_tag="L1V38_002566"
     CDS             3237..3914
                     /locus_tag="L1V38_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1317063.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3904..5046
                     /locus_tag="L1V38_002567"
     CDS             3904..5046
                     /locus_tag="L1V38_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBN1317064.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            5059..6036
                     /locus_tag="L1V38_002568"
     CDS             5059..6036
                     /locus_tag="L1V38_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1317065.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            6036..6944
                     /locus_tag="L1V38_002569"
     CDS             6036..6944
                     /locus_tag="L1V38_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBN1317066.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            6945..7697
                     /locus_tag="L1V38_002570"
     CDS             6945..7697
                     /locus_tag="L1V38_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBN1317067.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            7702..8649
                     /locus_tag="L1V38_002571"
     CDS             7702..8649
                     /locus_tag="L1V38_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBN1317068.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         3214 a         1102 c         1673 g         2747 t
ORIGIN      
        1 ttttgacatc attattgata attagtttag ttatatattt tttaaagatt aagaatcgaa
       61 ttatagatga ctataattca taggaggaga tataagtgtt taaaggaaaa acaatattag
      121 taactggcgg aactggttcc attggaagtg aaattgttcg tcagctttta aaatatgaac
      181 caaaagctat cagaatttat agtagaggtg aagaaaaaca attttatatg caacaagagc
      241 tctcaaatca cactaatttg agatttttaa ttggtgatat cagagactct caaaggattg
      301 attatgcatg tcgtgatgtg gatattattt ttcatgctgc cgcaatgaaa cacgttccag
      361 caagtgaata taatcctatg gaagctgtaa aaacaaatgt gatgggaact caaaatgtaa
      421 tagatgcagc gatcaaaaat aatgtaaaac attttgtagg tatcagtaca gataaagtag
      481 tgagtcctac taacaccatg ggtgcgacaa agttattgag tgaaaaatta ataatagctg
      541 ccaatcagta taaaggaaaa acagaaacaa tattttcttg tgtaaggttt ggaaatgtca
      601 tggggtcaag tggatctgtt attcctcttt ttagtaaaca aataaaaaac aataaagata
      661 ttactttgac agatgttgat atgacacgat ttatgatgtc aataccggat gctgcaagat
      721 tagttctgtc tgctgctatg aattcaaaat ttggagaaac atatgtctta aaaatgccgg
      781 caatcaatat tttaacttta gctcaatcat taataaaaat atataatgat acacatgatg
      841 aaaaatatag aggtgaaata aaagttgtag gtatcaggcc aggagaaaaa ttatatgaag
      901 agctaatgac tacagacgaa attgaacgct catatgaaaa tgataaaatg tatatcattc
      961 caccacacta tcatgctact gacgaactgt acaaagatta tgaaaaaatt aaaatcactg
     1021 catactcttc agatgcaaca gaattaatga gtggacagga atttattaga atcgcaaaag
     1081 agaataatgt cgtgacttgg taaggagttt tatgatgaaa tcagaagtat atgtaattgc
     1141 agaaattggt gtaaaccata atggaagtct agatttagct ttagaaagta ttgataaagc
     1201 taaagaatgt ggagctaacg cggttaaatt tcaaacattt aaaacgaata agctagtttc
     1261 caaaaaggct ccaatggcaa aatatcagaa ggataatctt aaagaggaca gttctcaatt
     1321 tgaaatgcta aaaaaattag aattatctca atctgatttt attagaataa aagattattg
     1381 tatacaaaat aaaattgatt ttttgtctac tccttttgat gaagaaagtg cagactttct
     1441 aaaacaaatt ggtgtacaag gatttaaaat tggctcagga gatttaacaa atttaccttt
     1501 tcttagaaaa atagatatgt atgggttgcc agttttatta tctacaggta tggctgatat
     1561 tcatgaggtc agtgaggctg tagattgttt catagatagt ccagttacta ttttacattg
     1621 tacttcaaat tatccggcta gttctgaaga tattaattta ttggcgatta acacattaaa
     1681 agaaatgttc gggatacccg ttgggtactc cgatcattca ttgggatatg atgttggtat
     1741 ttgtgctgtt gcgatgggtg ctaaggtaat tgagaaacat tttaccttgg ataaggaact
     1801 acctggtcca gatcataaag cttctttaga tcctcaggaa tttgcagatt ttgtaaagca
     1861 tattagaaac actgaaatat ttttaggtga tggtgttaag cgagcaatgc cttctgaact
     1921 tagtacaaaa gaagtatcaa gaaaaagcct agtggtcact gagaatttaa atgtgggaga
     1981 tattcttaca gagaaatctc ttacaataaa acgtcctgga aatggaatag ctcctaagtt
     2041 tttatatcaa tatattggca aaaaagttaa aagaccaata agtgcagata gtgttctgct
     2101 tgaggaagat gttgaatgaa aaaaatactt atagtaagtg gaacacgagc tgattatgga
     2161 atatataaac ctgttgctga gaatttacta caagataatt gggatgtatc atttgttgtt
     2221 tctggaatgc atttatccca taaatatgga tttactaaag aattgatctt agctgacgga
     2281 tttagaatta gtggagaagt tcaaagtttg tttttagaga acaataaggg aaacatggct
     2341 cggtctgtgg cattagagat aaatggtttc acaaatatat ttgaacaaac tagccctgat
     2401 tttgtattat tactagggga tagaggagaa atgttggcag ctgcgatagc ttgtttgtat
     2461 cttggaatca aaacagcaca tattcacgga ggcgaagtgt ctggtactgt agatgaatca
     2521 ataagacatg ccataacgaa aatagcatct gttcattttg ctgctacgga aaaaagcaaa
     2581 gagcgtttaa taaaaatggg ggaagattct tggagagttt ttcccgtcgg agctcctaga
     2641 atagatacta ttttaaataa tagattacct agttttagag atataaaaga aaaatatcat
     2701 ctaaaatttg aaaagaaaaa atacgttttg caagtatttc atccagttgt aaccgaacta
     2761 gaaaatatag aaaaacaaat tttagctttg atcaattcaa tggaacaaca atctcaacca
     2821 attatttgca ttttacctaa tagtgatgct ggtagcgaaa ttatcagaaa aatgtaccag
     2881 aaatatttaa aaacggatat tatttatatt acgaatttag agccggagga atacctgact
     2941 atattaaaag agtgcaaatt tatgatcgga aattcttctt ctgggataat tgaagctgca
     3001 tcattcaaaa taccagtaat aaatttagga accagacaaa atggacgaga acaatctaaa
     3061 aatattataa atgcaaatct aaatgaaaat gaaattgaaa ctgctttgaa taaaatacaa
     3121 gatcctcagt ttataaaaag cttgaaaaat gttaagaaca tctacggtga cggcaacagt
     3181 tctagaagaa taacaaaaac attgaatcaa atattgaatg atggggaaga tattaagtgg
     3241 attcaaaaac aaatagctta ttaaaatata ctagtgatcc atacattatt attggggctg
     3301 gcggacacgc aaaagtcatt attgaaacct taagattaga aaataagtta atatatggat
     3361 tttttgatga taagcaaaat aaaatgcaag atctgaaata tcttgggaaa ataaacgaat
     3421 tgaatagctg ggcggatagc aaaaaaaaaa tctataaatt tattgtagct attggtgact
     3481 gtgtagtaag aaaaaagatt ataaaaaaat tgaatatgcc aagtgagcaa tatggaatag
     3541 ctgttcatcc aagtgctata gtggcaaaag aaatttcaat tggttatgga actgttattt
     3601 ttgcgaatgc tgtaattaac ccagatgctg taattggaga gcatgctata ataaacacag
     3661 gtagcattgt tgagcatgat tgtagaatta ataactatgt tcatttatct ccaggtgtat
     3721 gcttagcggg tggagtacat gtaggtgtag gaactcaaat aggaattggt tctcaatgta
     3781 tccagatgaa gaaaattgga tcttggtgta tgataggcgc agggagcact attgttaagg
     3841 atattccctc acattcctta gcttatggca atccagctaa aattaagaaa gaaggaatta
     3901 attttgaatt ctagaatttt attatcaagt cctcatatgg gaggaacaga agaaaaatat
     3961 gttgctaagg cttttaaaga taattggata gcgccattag gtgaaaatgt ggataaattt
     4021 gaagaaagta ttacaaaata tactggttct aagggcggag cttctgcgtt aagttcaggt
     4081 acagctgcca tacatcttgc cttaagactg cttaatgttg gaaaaaacga tattgtcttt
     4141 gctccttcat ttacttttat agctacagta aatcctattt tatatcaagg ggctgtacca
     4201 gtgttcattg actcagaacc taatacatgg aatatgagcc ctgttgcact agagagcgca
     4261 ttagaagaag ctgaaagaaa caaccaatta cctaaggcaa tcatcgtagt gaatttatat
     4321 ggtcaaatgg ctgattatga acgaatttta gctattgcaa accaatttaa tgttccagtg
     4381 atagaagatg cagcggaatc gttaggttct acttataagg gaatttcgtc aggcttattt
     4441 gggacaattg ggatctattc atttaacggt aataagatca tcacaacctc aggtggagga
     4501 gctctagtgt ctagtgataa aaaatatgtt gagcattcaa gatttttagc aacacaagca
     4561 agagatcaag caccgtatta tcaacatagc gaaataggtt ataattaccg tctaagcaat
     4621 atttctgccg gtatcggacg tggacaaatg gaagtattga atgatagagt agctaaacga
     4681 agagaaattt tcaatcgata taaggaagct ttttctggaa ttgatagaat tgaaatgatg
     4741 ccagaagtgg atggcatggt gccaaatcgt tggttgtcta ctttaacgat caatgattat
     4801 aattctattg atcaagtagt taacgtaata aataaactaa atgaaaaaaa cattgaaaca
     4861 agagctttgt ggaaaccact acatttgcaa ccagtatttc aaggggtaaa aatgtattac
     4921 catgataata atcttagtgt gtcagaaaag ttatttaata gcggcttatg cttaccttct
     4981 ggaagtaata tgacagatag tgaacaagaa tttgttattg atgagtttaa aaaaatattc
     5041 aagtaggtgt gatattttat gaacatagga attattggtt taggttccat ggggaaaaga
     5101 agacttagac tcattcaaga acactttaat gatattttac tatgtggtgt tgatactaat
     5161 gaggcgagac gaaaggaagt tgaaaaggaa tttggaatac caacttataa tagtctaaca
     5221 gaggcaaaaa atttgtttga aataaattca gtttttgttt gtacatcccc tataacccat
     5281 gaatttatta taaaagaggc tttaaattta gattgtaata tctttacgga aatcaattta
     5341 ttaaatgaat attatgatga aataatcgaa gtagctaaaa agaaagatag attactttat
     5401 ctatcttcta catttttgaa gagaaaagaa attcaatata ttaagtctaa agtgacgcat
     5461 aataaaaaaa tttcttatca ataccatgta ggacagtatt tacccgactg gcatccttgg
     5521 gaagattatc gcaatttttt tgtttcaaac aaaaaaacta atgggtgtag agaaatattc
     5581 gctattgaat taccttggat tatagataca tttgggaaag ttaaatcgtt tactgtaatg
     5641 acccagaaat tatccaatct tgatattgat tattcggaca gtttcactct tattattgag
     5701 catgaaactg gtatagttgg aactttaagt gtagatgttg tttcaagagt agctaaaaga
     5761 aatttaacta taattggtga aaagatttta atagaatggg aaggtaaccc ggattctcta
     5821 ttttcatgga atgaagaaac ttctagtatg acagatattc aattgtacga tgaggttatg
     5881 catgataata attattcaca tactattatt gaagatgcat atttagagga gattaaagaa
     5941 tttttcacgc ttttggaaaa gaaaatggaa ccccaatata cttttgaaaa agataagtat
     6001 attattaact taattaacga cattgaggta aattaatgat gaaagtaatt ttttttgggt
     6061 tagggtcaat tggaaagaga catctaaaaa atctaataag ctatggaaaa aagaattcta
     6121 ttaattttga tataacagct tatagtagca gtggaaaaaa agagtttgaa gaaataacgt
     6181 atattcaaaa tagagacgat ttggatacac attatgatat agcttttatt acaaatccga
     6241 cttttaagca tctggaaaca ctaaatgtaa ttgttgaaaa agttgattac atatttttag
     6301 aaaaacctgc tttttctgag agtattgatc ttactcaata taattatgat tacaaaaata
     6361 tttatgttgc tgctccactg aggtataaaa atatcatgga agttgttcgt aatagtattc
     6421 aaagtaaaaa agtatattct gtaagagcta tttgttctac ttatcttcct gattggagaa
     6481 aaggtactga ttatagaaat aattattctg cctttaaatc tatgggggga ggagtagaat
     6541 tagactgtat acatgaattg gattatatta taaacctatt tggtttccct aaatcagtaa
     6601 aaaaacagtt tggtaaatat tcgaatcttg aaattaacag taatgattta gcaacatata
     6661 tattgagata cgatgataaa attatagaaa ttcatttaga ttattttgga agagttccta
     6721 caagaaaatt tcaattgttt actttagatg aatgtatcaa tgttgactta ttaaataata
     6781 aaataagttt tgaagaaaac attgttaaag aaatgcctga atctgctaat gatatgtatg
     6841 agaaggagtt gaaatatttc tttgaaaacg tagtaacagg caaagaaaac tggaatgatt
     6901 tatatcatgc aaacgaagta ttgaaaatag ctgaggagaa ataaatggaa attttattta
     6961 ctatttgtgg tagagctggg tctaaggggt ttaaaaataa aaatttgaaa tatttggcag
     7021 gaaagcccct agtccatttc gctttagcaa tgatagatat ctatcaacaa aaacatcctg
     7081 aacataattg cacgacttgt ttgaatacgg acagtaatga gttagtagaa ttgacgacta
     7141 agttaaatcc gtctgtgaaa attgtagaac gtaaacctga attagctaca gatactgtag
     7201 ggaaaattga agtgatacgt gattcattct tacaactaga aagagaagat aatatatttg
     7261 atttaattat agatttagat ttgacttcac ctttacgtga agtttctaat cttgaagaat
     7321 taatagatga acatctaaaa aatttagata aagacgtcta cttttcagtt gtttctgcaa
     7381 gacgtaatcc ctattttaat atggtaaaaa gaattgaaaa tgaagttact atagttaata
     7441 aatcaagata cacatctagg caacagacac ctgaagtttt tgaaatgaat gcctcaatgt
     7501 attcttttaa acctgaattt ctaaaaaaaa gtaattatat ttttgatggg caatgtggga
     7561 taataaaaat gagagattat ctaattttag atattgatag tgaagaagat tttaaatggt
     7621 tagaattttt gtttcctaaa tttttagaag attcttcgga gcttcaagat atctataatt
     7681 atttatatcg gaggtaaaag gatgagctgt tatcttatca ccggtggggc tggcttcatt
     7741 ggttctacct tagccaatca tttaggagaa gaacatgtgg taatcgtcgt cgatgactta
     7801 tcaatgggaa aagtagaaaa tcttgatatg acgaaaaata tcacttttat tgagggagat
     7861 gtcgctgaga aatccttgat ggaagagatc atgaaagcta ataaatttga ttatatcttt
     7921 catttagcag cagttgctag tgtggcagat tcagttgccc gaccagtaga aacacatcgt
     7981 gtgaattttg aaagtgtatt aatgatttta gaattgatcc gcaagtatca acctgattta
     8041 aaacggatcg tgtttagttc ttcagcggct gtttatgggg atgaaccgac tttaccaaaa
     8101 aaagaagagt ccgtgattcg cccattgacg ccttatgcgg ttgataaatt cgctgcagaa
     8161 caatatgtgc tagattattg tcatttatat gatgtacccg gtagcgcagt tcgttttttc
     8221 aatgtctatg gtccaaatca aaatccgaat tctccataca gtggtgtgat ttctattctc
     8281 gtagatcgct ataagaaaca aatcgtagga gaagcaactt catttacatt atttggtgat
     8341 ggaagccagt ctagagactt tgtttatata gatgatgtaa tccaagcatt acttttagtt
     8401 gcgaatgagg aagctgcact ggggaaacaa ttcaatgttg gaacgggtaa agcaaccaca
     8461 cttttggaat tgattcatgc aatcaatgaa attctcggtg tagaattgac acttgaatac
     8521 aaagaagagc gttcgggtga tatccatgac tctctagcag atattactaa gatccagtca
     8581 attggctatc aaccgaaata tggtatttta agtggaatga ctaattattt gaaaactgaa
     8641 atcaattaaa acatactaag ataagattag agggtaaatt caggctcttt gtcaataagg
     8701 actgatgagt tttgtaaaat caaatctggg atagaa
//
LOCUS       DAFLWZ010000099         8687 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000099 DAFLWZ010000000
VERSION     DAFLWZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.101"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            175..519
                     /locus_tag="L1V38_002572"
     CDS             175..519
                     /locus_tag="L1V38_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBN1317069.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="L1V38_002573"
     CDS             520..939
                     /locus_tag="L1V38_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBN1317070.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="L1V38_002574"
     CDS             complement(1031..1381)
                     /locus_tag="L1V38_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317071.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="L1V38_002575"
     CDS             complement(1347..2678)
                     /locus_tag="L1V38_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBN1317072.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="L1V38_002576"
     CDS             2934..3500
                     /locus_tag="L1V38_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1317073.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="L1V38_002577"
     tRNA            3645..3732
                     /locus_tag="L1V38_002577"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            complement(3784..4989)
                     /locus_tag="L1V38_002578"
     CDS             complement(3784..4989)
                     /locus_tag="L1V38_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317074.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5127..6015)
                     /locus_tag="L1V38_002579"
                     /pseudo
     CDS             complement(5127..6015)
                     /locus_tag="L1V38_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6102..6302)
                     /locus_tag="L1V38_002580"
     CDS             complement(6102..6302)
                     /locus_tag="L1V38_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317075.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6331..6753)
                     /locus_tag="L1V38_002581"
     CDS             complement(6331..6753)
                     /locus_tag="L1V38_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1317076.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6770..7192)
                     /locus_tag="L1V38_002582"
     CDS             complement(6770..7192)
                     /locus_tag="L1V38_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317077.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7483..7674
                     /locus_tag="L1V38_002583"
     CDS             7483..7674
                     /locus_tag="L1V38_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317078.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7685..7951
                     /locus_tag="L1V38_002584"
     CDS             7685..7951
                     /locus_tag="L1V38_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317079.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(8192..8671)
                     /locus_tag="L1V38_002585"
     CDS             complement(8192..8671)
                     /locus_tag="L1V38_002585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317080.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
BASE COUNT         2855 a         1448 c         1559 g         2825 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatatc aacgattaga cacgatttcg atcgtgtctt ttttgttgta
     3781 tatttagcct aaaatgtttt ttgactcccc ttttgactcc ccctgagtac tgttcttcat
     3841 aaatgctaca aaattattga tgactttttt gttttgagtt tcagttacat gagtgtaaat
     3901 atttgaagta gtttgaatgt ctgcatgccc taaacgttcc tgaacatctt ttaaagaagc
     3961 tcctgattca aaaaggagag aggcatgagt atgtcgaaaa ccatgagtag tgattctttt
     4021 agtcaattct ggatgatgct tatatatgac attaagccac gaacgtgaaa ctgtagggtt
     4081 atagagaaga ccatcatggt gaaaaattaa gttttccctt tggattgtaa cgatcgtttt
     4141 gttttttgta taatactttc tcaataaact gatcaaatca ttgtccagat aaatttttct
     4201 ttttccagat tttgatttag gagtatttac gatcaatctt ccttgataac ctcttgttac
     4261 agttttattg atattgagtg ttttgctctt aaagtcaata tccgaccagg tcagagcaaa
     4321 agcttctcct tttcttatac ctgtaaaagc caatagggaa aagaataaat atctttcatc
     4381 atcatcgttt cttattgctt ctaaaaattt gattaattct tctttagtat aaaattcgat
     4441 atttttatct tcgatatcta gagcttctcc acgtggaata gaaactaatt tcataggatt
     4501 gctagttata atttgtaaag aagcagcgta atcaaaaaca ttagatgtgt aattttttat
     4561 tttcttaaaa attttaggat ggctatcgga ccaagtgttt actgcttctt gacagaaaaa
     4621 aacgtctatt ttgtcaatga acttatctcc aaacactttt aagatgtgtg tgtcaaaaat
     4681 ttgtttggtg gaggaccaag tgctttcttt aactgtcttt ttataatttt caaaccataa
     4741 gccgtaaaca tattcgaatt tcttgctctt ttgagctgta gaagcttgca gtcctttttc
     4801 ctgtatatct gcctccaatc tttttaaagc tctctcagcg gctaatggcg tactaaaacc
     4861 tcgtctcgtt gtttttcttt tttttcctgt tagaggatca actcctaagt acagactaaa
     4921 ctgatatttt tcttcgcctt tttttgttaa gtgcttttta attcgtttat caatttcttt
     4981 ttttgccatc tttatctttc ctttcgtacg tttgttcggt tgtacagcgg atttcgagat
     5041 ggtaaaatag ggtacaacaa atagacctac tttaccgtag ctctttgcac atttgcgttc
     5101 ttggtcgggc ggcaaatgtg ctttttttat ttcactctta gttcttgtcc tggataaagc
     5161 atgtagttgt ttggatccat accgtttaat gcaaacagtt gatctaccgt aattccagct
     5221 cgttcagcta tttgtttggt cccttcacca ggttgcaaag tcaaggtttc ggtttcagat
     5281 gaagaaggtg ccgttggttg agcttgatta gctggtacat aatcttgtgg tactgattgc
     5341 tccgttgaac tgggagtggg tgaaacttgt tcaacacttg aactaggagt agcttctgca
     5401 tagttttcta cactttcagc agagtaagta ctactagttt caggaggcgt attctgcgca
     5461 atagcagctt gttctacagt actagaagat gcaatagtac tttctgttgt agtcgaagat
     5521 gattgttcgt tgctacttgt tgagctagta gttgttctag attctttagt ttttttcctt
     5581 tttgtagggt ttcaaaacta atttctcatt atcatcagat ttgttaggct tttctggagt
     5641 taaaataata tttttatctt ctttgctgac agtatatttg gcatcattat ctttgtcttt
     5701 atcatctttc caagtcataa catcgccttc aagtgtatac tcaaatttgt aattcatttg
     5761 gtcgactaag cttttagcaa attcttctcc catagcctcc caatcgttac ttgaagttga
     5821 tttcatagaa cttgtgtcaa cactaaaaga tacgacgtga tcagaaaatg atacgatcat
     5881 attaggttcg tcatctttgg ttgcttcaat caaccaatca ttagctttta aatcttctgt
     5941 agttactttt ttaccacaag cagtgaaaag taacagagaa gcaaaaacta ataaacttgt
     6001 tattactttt ttcatttttt attcctcatt tctatgatat gatttttatt ggggaatctt
     6061 agaaataagg tttcgagtcc gtgttgctgc acgggctttt tttatttaaa taaatcccaa
     6121 aaactgaatg tagttttctt gtatacttta ttgtaagcag ccttttttgg gtctttaatc
     6181 cagccgctac cttttttccc ataaccagga ataactgctt tttttacttt tctttttgct
     6241 tttccagtgg ttctagcgct tatggatttt tttatacttg gttttctcat tcctattttc
     6301 atctatatcc tccttacgtt gtattataat tcacaagaaa cgatcgaatt catctggtaa
     6361 tccaaagcag acgagctttt catattttgt catatgatca aagccgtcta aagttggatc
     6421 aatagtcaga tgagttgcga aataatttgc ttctttttca atttttaatt cagatactag
     6481 cgttttttta gacaacatag gtgtgttttc attcggatgc aaaacacagt ggcctaattc
     6541 atgactacaa gttatccatt ttcccatctc atctaaacta gaatttatgt ggatcatttt
     6601 tatctgtttg aatttactat agtaaccata aatttctccc aaatcttctt ctaaaactag
     6661 tatcttcaat tctcgtgcaa ttctaaaagg attgcgtgtt tgatatagtt ttaccagctt
     6721 attaattttg ttatcaattt gaggtaaata cataaacaac gtactccttt taatcgcgat
     6781 attttttagg tgtgtatttt ttcttagctt ctattttagc tattcgcaaa gcattctcta
     6841 aagaaataat gagagcttca cgtgtcgctt cactcatttc attatctttc ttcgaaaaag
     6901 ccattccatc agcattagat aaatcgtcga ttaatgactg caattctttt tggatatcac
     6961 gctcgtcttt ttctgttaaa tcatagtatc tttttttctc agtacgtcct agcaaataat
     7021 ctacagatac gtcgaagtag tcagcaattt cttgtaactt ttcggcagtt ggctgttttc
     7081 ctgcgtttaa actataaaag taattctctc cgtacttcaa atctttagcg acttgttgaa
     7141 ggtttttatt cttgtttttc gctagttctt ttattctttc aaatgttgtc attccaacgt
     7201 tcctttccaa cacgaaaaaa taatttacga aaaagagtaa aaatagcttt acaattttac
     7261 gatatagagt tattatttat ccgtaagtta atttgataga aaaaagcaaa ctaaaaacac
     7321 accttatagc ataaagtttg gcgaccaagt gcaaataaaa ggttttgtta taggcttatt
     7381 tctctatgta ttcattttac tctatagtgt aaaaatgtca atggaaatta tattttttct
     7441 atcattttaa cttacaaatt tataaaaaaa ggaagtgggt taatgtcaaa cttggataac
     7501 ggtcgtgcgg cgatcaaaga gtttatgaaa gagaatggaa taactatgga tgatttggct
     7561 actgcttatg gtcacacgcg tgtacgaatg caacaaattc ttgatggaca ctggagtgga
     7621 ccaaaggcaa acagaactat tctagagatc atccgtgatt acagaattcg ataggaggca
     7681 agtcatgaat attctaagcg aagagttttt gactcgttta agaattgcaa ttgttgaagt
     7741 tgtaaaggac gcacttagtc aactttcaaa aaagaatttg tcagaaacac gatatttaaa
     7801 aaagatcgaa gctagaaaat atgtgggagg tgtaaacgat caaggttttg agaagttaat
     7861 agctcacggt ttaaaagaaa ttcgtataga tggcttttta agatatgaca aaaaggacat
     7921 cgatgaactg atggctaaat acaaaattta aaggaggtca acatgggaaa gtttaatcga
     7981 acattagtat tcagcgcgcc actaattatc tacgctttag gtctatgggg tagtagacaa
     8041 gcattaatcg gcacgatcgt ttacatgctt tggattttca ttgggcttga tgaagctgag
     8101 tacagagcga aaaagccagt cgggagggac tgactaaaaa agtctaatgt ctataagaaa
     8161 ggtttgacaa taaatgaaag aattattttt tttaataact ttcatcattt tttctatcag
     8221 tgttttctac attaaccttt gcgttgctag atttgctttg aaaagtttta ggaacagcaa
     8281 acgaaaatag agctataaaa gatacgaatg tagtagctac gttaaattgc tctttagaaa
     8341 acgtcaatgt cattggaatg ataattgata tcgatgagaa aatctttgcg ataataacta
     8401 tccatttttc aattataaac atttttaaat taagcaccat tagacaaaat gtagttccta
     8461 tatagaggat aaatgaagat agaaataaac atattagtcc agttttaaaa aaagagaagt
     8521 aatctatgtg ggcaaattct gttaatatgc ttttttgatt taacacaatc aaactactgt
     8581 tggacaaaaa tgacagtaag gaaagagttg ctccgattac taaataaaaa atagttgtta
     8641 acaatattat attatcaatt tttctgctca tgttttcacc ccaccag
//
LOCUS       DAFLWZ010000100         8677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000100 DAFLWZ010000000
VERSION     DAFLWZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.102"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..199
                     /locus_tag="L1V38_002586"
     CDS             <1..199
                     /locus_tag="L1V38_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1317081.1"
                     /translation="QQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKA
                     KNDVEDTANKAQQIVNEHTIQ"
     gene            627..1019
                     /locus_tag="L1V38_002587"
     CDS             627..1019
                     /locus_tag="L1V38_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317082.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(1192..1374)
                     /locus_tag="L1V38_002588"
                     /pseudo
     CDS             complement(1192..1374)
                     /locus_tag="L1V38_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1361..1558
                     /locus_tag="L1V38_002589"
     CDS             1361..1558
                     /locus_tag="L1V38_002589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317083.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(1601..2176)
                     /locus_tag="L1V38_002590"
     CDS             complement(1601..2176)
                     /locus_tag="L1V38_002590"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1317084.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(2331..2857)
                     /locus_tag="L1V38_002591"
                     /pseudo
     CDS             complement(2331..2857)
                     /locus_tag="L1V38_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3314..4825
                     /gene="gadC"
                     /locus_tag="L1V38_002592"
     CDS             3314..4825
                     /gene="gadC"
                     /locus_tag="L1V38_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBN1317085.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            4838..6238
                     /locus_tag="L1V38_002593"
     CDS             4838..6238
                     /locus_tag="L1V38_002593"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBN1317086.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(6403..7838)
                     /locus_tag="L1V38_002594"
                     /pseudo
     CDS             complement(6403..7838)
                     /locus_tag="L1V38_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            8231..>8677
                     /locus_tag="L1V38_002595"
     CDS             8231..>8677
                     /locus_tag="L1V38_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBN1317087.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         2823 a         1399 c         1537 g         2918 t
ORIGIN      
        1 ccagcaaatt aatcaaatgt tgagtgaaaa aaataacatt caaaatcaac tgcaagctac
       61 tcagcaaaag ctagaagaag aaaagtcaaa aaatagtagt ttgaataatt acattgaaaa
      121 gcttcaaaaa gctaaaaatg atgtagagga taccgcaaat aaagcacaac aaattgtaaa
      181 tgaacataca atccaataga tatagtttta atttaacaaa tggtatgttt ggagataatg
      241 agatagaata taaatgtcat aatattatac aatctaaaca ccgtttcctt ttctattttt
      301 gatgacatca gtatatagct actcgaaaga gtagtctttt tattattctc gcttattatt
      361 gatatgaaaa tttcgatttg acaaaaggta ccgaataatt ttgtaatatg aattattatc
      421 aagaagtaat tatgatgata acatatggaa actagttagt aataataaca ggtgattaaa
      481 cttttgaacg acttgtaatt ctatattttt tcttttaagt aaaaaatata ggtgattttt
      541 tttgacttca tatttataat aaagacacgt aaatcaatta tttttcattt tactttaact
      601 aataatgttt atttggaggg attattatgt tagatgatag attgacgtgt tctaattgtg
      661 gtacattatt ttactatgag gaagttagaa atattgtaaa acatagaaaa aaagaaatgc
      721 ctatacgttg tccaaattgc aatgaagtta ttaagcgaaa gttgtctcat ggttattttg
      781 tcagctacga actatatgaa gaaagtaaaa taaatctgaa aaaaaaacca aaatactata
      841 aaaatttgaa aactggagct attataactg aaaaagaatt taaaaattta gtgactgaag
      901 aagaaagcag gttttataat ttgtctggta atatttgccc tggatttatg gatcagatta
      961 ttgaaaatga gtcaattgaa tcaattgaaa actatgttcc tgttgactta ccaaaataga
     1021 aaaaataatc ctgtttttac agtgaattat tttaattttg attttcaata aaaatatatt
     1081 acaataataa tcgtaatagc taatgaaaca atttctcaat ctttttacca ctccaaacag
     1141 ggagcgtcaa taattttgtg taaataactc gtccttctgc aaaataatgg gttactcagt
     1201 aaacattgaa gctaatgtat ccgtcacttg ttggaagcct ttatggcttc tatttaagaa
     1261 tttttgattg tatgtatcaa agatggatac taggaaacgc tctagtgatt cttcattttg
     1321 aaactgctct tttctgcggc tgtatttctt gatttgttta ttgaaagatt cgattgtaga
     1381 accagaagga atggagaaca cttttgaact ttacaacaaa actactgttg ataaattaat
     1441 tccaatttta gttccaactg atttaaatgg tcatgatgtt ttacttcgtt ttaacggatt
     1501 tttaggtgag gattatagat acctaaaaat ttctgatcct caacctttaa cagaataata
     1561 aaaaacgtgt aatcaattat ttgattacac gttttttatt tcaatcttcg ttgtagtagt
     1621 ggttgcgaca taccgaaagg taatcttcat tacctcctac tacaatctgt tcacctgaat
     1681 aaactggaat accatcaaca atacgagcat tcattacagc ctttttattg caaaaatggc
     1741 aaatagtttt aatttcctca attttatcag caaatgtcaa taatgcttcg gatcccttga
     1801 agagattatt ttgaaaatca ttcttcaatc catagcaaat tactggtact tcctcattca
     1861 ttacgataag tgatagatca ataatattct ctctacttaa aaattgagac tcatcgacca
     1921 aaatacaatc aacttttccg tactgatcaa taatctccac taattctccg tacacatcca
     1981 tttcagaagt aattgcaata gctggtttcg aaacacctat acgactctca acttttccaa
     2041 atcctgatcg agtatctatt gcgcttgtca ttatgataac tctcttccct tgttcttcat
     2101 aattatgagc cactttcagt agctcaatac tctttccact attcattgtt ccatatctgt
     2161 aaaataattg tgccattaaa tttattccct tcttttacaa ttcaattatt ccttaattcc
     2221 atctgctttt atgcagctgc tcgtttattc cttgatatgt ctataacatc tactatccct
     2281 aaaaccaatt tataagccat tagagatggt attcctgaac atctctcata ttgttttttg
     2341 agtggtatat catctgaaaa actgaaggaa tcatgaaaat agcgacatac ttatcattta
     2401 gagttctaac tttaaatgca tttacttctt cagtcagcac tttagtcatg ttggacatgg
     2461 tttggggcgt gtagtgatgc ccatacattt tctcaatcaa gtctgcgatt tccgacatgg
     2521 taataccttt tcggaagagg tgaatgacgg tctcctctaa tgtgtcattc gtccgtctat
     2581 aagcaggaac agtctgttgc ttgaactcgc cattgcggtc gcgcggaatc tggagatgaa
     2641 gttccccata ctcggtcttg accgtacggt cataggagcc gttacgagaa ttacccgtgt
     2701 taaaaccaat gcgatcgtac ttttcgtaat cgaggaaagc cgttaactcc gttttgagaa
     2761 gcgtattgac agctttttcc aaatggacac ggaataatcc attcaaatcg cctttgttcg
     2821 ctagagtctt taggatttct gtagtaaaat cgttcatatg gaagtcctct tttctgtgaa
     2881 tgtgttgtgg taactctatt ctacagaagg gacttccttt tttctattta cacaaaatat
     2941 tttacactct caacaaaagt atcttcgatt aatacttgct caagttatgt gcagctacga
     3001 aaaagtaggt accgaggtac tttctttttc gcagcttttt ttggacttat gagaagtaca
     3061 ttcgctggaa gaatacgata taaaacgagc tttttcacta aagatattaa tagagtgaaa
     3121 gaaacaagct tttgttgtca gttttttcac ttttctaaaa atgaaaataa aaaattctgg
     3181 aagtggagaa gaattttgct tgctatactt tgtcttgtag aaaagaggta gacaaaataa
     3241 tgcaagctca aataagcgat tttccataac cttggtagga atgacaaatt aaataggaaa
     3301 gggaagtaat aatatgaata aaaaaaagtt atctctattc ggtttttttg ccctgacagc
     3361 ttccatggtt ttgactgttt atgagtatcc gacctttgca acatcacaat tacatttggt
     3421 tttctttctt cttttgggag gtattttatg gtttctacca gttgctttat gtgctgcaga
     3481 aatggcaaca gttgaaggat ggaaagatgg tgggattttc agttgggtta gtcaaacttt
     3541 aggagaacgt tttggttttg cagctatttt tttccaatgg tttcaaatta cagtaggttt
     3601 tattacaatg atctacttca tactaggagc gctgtcgtat gtaattaatt ttccagagct
     3661 taatacagat ccatttatca agtttattgg tgtattagtc attttctggg tactgacttt
     3721 ttcacagttg ggcgggacca atcgtaccgc taaaattgct aaagcaggat ttgtcattgg
     3781 aattgttatt ccttcgatca ttctctttgg tttagcagca gcctacttta tcggcggtaa
     3841 tccgattcaa atggctatta atgcgaaagc ttttattcct gacttttctc agctttcaac
     3901 tttagtagta tttgtatctt ttatattggc ttatatgggc gtagaagctt cagcatcaca
     3961 tattaatgag ctggaaaatc cccaaagaaa ctacccattg gcaatgtttt tactagtgat
     4021 tttggccatc gccttagatg caatcggcgg tttctcagta gcagcggtta ttccacaaca
     4081 tgacttgtct ctcagtgctg gtgtaatcca aacatttgaa acgcttattt tacattttaa
     4141 cagtcattta cattggttgg taaaagtgat tgctctcatg attgcctgtg gcgttatggg
     4201 tgaagttagt tcttgggtag ttggtccatc acgagggatg tttgcagctg ctcagcgagg
     4261 tctgttacca gttttcttcc ggaaaactaa taaacaagac gttccagttc cgttgattat
     4321 gatacaagga attatcgtta ctatttgggc agcagtctta acttttggtg gaggaggcaa
     4381 caatttatca ttcttagtag caatctcctt aactgttgtc atttatctcg taggatattt
     4441 actatttttc ctaggttact ttgtattagt ttttaagaaa aaagacttaa aacgaactta
     4501 caatgtacca ggaaaaactg ttggcaaaac gattatcggt ggaattggtt ttattttatc
     4561 agtgttcgca ttgcttatct cttttgtacc accagcttca attgcagcta gtgagcaccg
     4621 aacataccaa atcatactac ttattagctt tgtagtgact gttcttttac cttttatcat
     4681 ttatgaagta catgataaaa gtgctcacac aactattgag gaacctactc acgtgaaagc
     4741 tgaagacgtt aatcccgctg tttatccagc tgctagagga gagcaccacg ttacaaaaaa
     4801 tgatgaacat attttaaaac attaggagga attcattatg ttatacggaa aagataatca
     4861 agaagaaaaa aactatttgg aaccaatttt tggctctgca agtgaggatg ttgacttgcc
     4921 taaatataag ttaaacaaag aatccattga accacgaatt gcttatcaat tagtacaaga
     4981 cgagatgttg gatgaaggaa atgcgcgatt aaacttagct actttttgtc aaacgtatat
     5041 ggaacctgaa gcagtgaaat tgatgaccca aacgttagaa aaaaatgcaa ttgataaatc
     5101 agaataccca cgaacaacgg aaattgaaaa ccgctgtgta aatatgattg ctgatttatg
     5161 gcatgctcca aataatgaaa aattcatggg aacttcaacg atcggctctt cagaagcctg
     5221 catgctgggt ggtatggcca tgaaatttgc ttggcgtaaa cgtgctgaaa aattaggtct
     5281 tgatattcaa gcaaaaaaac ctaacctggt gatctcttct ggttaccaag tttgttggga
     5341 aaaattctgt gtatattggg atgtggaact gagagaagtc ccaatggatg aaaaacatat
     5401 gtcaattaat ctagatactg tcatggatta tgtggatgag tacacaattg gtattgtagg
     5461 tattatgggt attacttaca ctggtcgtta tgatgatatc aagggtctga atgatttagt
     5521 tgaagctcac aataaacaaa ctgactataa agtatacatt catgttgacg ctgcatcggg
     5581 tggcttttat gcaccattta ctgaacctga tctagtttgg gattttcaat tgaaaaatgt
     5641 tatctcaatt aattcttcag gtcacaaata tggtttggta tatccaggtg tgggttgggt
     5701 cttatggcgt gaccaacaat acttaccaga agaattagta tttaaagtta gttacttagg
     5761 tggagaaatg ccaactatgg ctatcaactt ctctcatagt gcagcacaac taattgggca
     5821 atactacaac tttgtacgct atggctttga tggttatcgt gatattcacc aaagaactca
     5881 tgatgttgct gtttatttag ccaaagagat cgaaaaaact ggtatttttg aaatcattaa
     5941 tgatggatca gaattgccag ttgtgtgcta taagctgaaa gaagatccca atcgcgaatg
     6001 gacactatat gatttatctg atcgtctgtt aatgaaggga tggcaagtcc cagcctaccc
     6061 attacctaaa gacttggatc aattaattat tcaacgctta gttgttcgag cagactttgg
     6121 aatgaacatg gctggtgatt atgtacaaga tatgaaccaa gcaattgaag agttgaataa
     6181 agctcatatt gtttatcata aaaaacagga tgtgaaaacg tacggcttta ctcactaaaa
     6241 ttcttcagag aaatataaaa gaagttaatt aactaataaa aggagttgtg attaccacac
     6301 agctccttaa atctatttga ataaatatat gatattcatt tgttacactc tcaatcttag
     6361 ctgttgttct attcatcatt actcttattg taagtagttc agtcaaattt gcttgttcaa
     6421 ttgatcgata acagtatgaa ttgtttgaaa agtaatcgga tatataattg ttttctcact
     6481 acctaagcct tcttggtata aagaactatc gcaaagtata atccgctgag tacaaaagaa
     6541 agtgtcgtct actatttctc taagttgttt acaaatgata ttactaatag aaaagtgttc
     6601 tcccaaaatg tcttctaact gttgtcgata gtataaatac ctaaagtctg acggagctac
     6661 tatgaacact tcaattggag atttccgttt atgctcattt aaaagactta aactaatggt
     6721 tagtttacga atagaattct cattccaacg cagaaataaa ttgttttgtt ttcgccattg
     6781 ttcaagaatt tcatgaactt ctaagtacaa agcgcgttgc tcttcattta acaagtaagt
     6841 cttatcaggt tgaaatatct gaatatcagc ccaaagtgag cggataaacg ggagaagtgc
     6901 tttatcaaaa agtatctgat tttcttcaga tatattcaga gataagataa gtttttgact
     6961 gagctcaatc accaaagggt tatctgctac atggttttga taaacaacgt tcaagtcttt
     7021 ttgtaacaat tcaaagttat cgcatagata atttctagag ttgaatagaa agtagatata
     7081 aaggcattca tcttcgtcat gacataaaga gaaagaaagt tgctctaatc ctttctgtat
     7141 tagctgaaac aagggagtat gtcgggcaac tcttttttct tcctgactaa aatatattgg
     7201 gttagtctta gatctctgca aaccgatagc gatacctaat aaaataaatt gtttttcaac
     7261 tgtagggtaa cttcttgaaa aaaatgtttt tctacataat caatcaattg ttgaccgctt
     7321 tgaataattg atttatttag ctggatcaac tctgtccgat ttgtctcata gattatcgtt
     7381 agtaacaaac ttcgataatc cttttcagga atttcaaaat ggccatcagc atttaagtac
     7441 tgcatttgtt taaaaaaatt aatcaactca tttcgtaagt tgtaaacttt gcttaacgaa
     7501 atgaaggtag tatcagctat attactccaa ttgtgttccc ctgataaata atgtcctagt
     7561 acattgaaaa agtcagagcg ctgatagatg agttgagtga gtgccaacct cgaaaacgaa
     7621 gagtcgaatg cgactgtaaa gctacttcta gatttctcca ctgaaataat ttgctgatgg
     7681 agtatgtcgg taatgcattc caagtcgtta gtgacagtga gtgggcaaac gttcaattga
     7741 tctgctattt cgcgaatctg aatggtccct ttttcgtgta attgctcaca aatgtaaact
     7801 tgacgaaaaa tacttttctc cagataggtt tccaacatag tactcctcct agtcatttta
     7861 tacataacta ttataactct accaatcgga atagtcctgt aatatattga atcaaaaata
     7921 taaattataa aataattaga tggggtattt ggtttaagta tcccttatat agtaataaat
     7981 ttataggtgt gattctcgaa ttaatacccg aaaatgtgag agaattttta tggatttttt
     8041 aggatacaaa ttaattattt ttgcttttat cctgattacc agtccagtac tgtcggtatc
     8101 ccattttgca gcaaaatcat gttgataaag tgacaagaag actgatgaga tatattatcc
     8161 aaattgagaa gataattaat cggattcttg agtataccct actttttaag aaagtagggt
     8221 atacaagcgt atgaataaag acataacttt ccctgtgatg gacgttcggc ttgttccaat
     8281 taccaaaata caggcgaacg attataatcc caatcgagta gcgtctccgg aaatgaactt
     8341 attggagctt tctatcattg aagatggctt tactcaacca ttagtttgtt attacaagga
     8401 aaaagaagag aagtatatct tggttgatgt gcttcatagg tatcgtgttg ctaaggaaag
     8461 actcaactta aaagttgtac cggtaacagt tattgataaa cccatagaag aacgtatggc
     8521 ttcaacaatt cgacacaatc gtgcaagagg gacccatgaa ataagaggaa tggaaattgt
     8581 catccaaaga ttagtaaaaa atggatggtc agacaagaga atatccaaag aattaggcat
     8641 ggacattgaa gaaatttttc gctttaagca agtgtct
//
LOCUS       DAFLWZ010000101         8422 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000101 DAFLWZ010000000
VERSION     DAFLWZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.103"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            323..1648
                     /locus_tag="L1V38_002596"
     CDS             323..1648
                     /locus_tag="L1V38_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1317088.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1641..1991
                     /locus_tag="L1V38_002597"
     CDS             1641..1991
                     /locus_tag="L1V38_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317089.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1973..2158
                     /locus_tag="L1V38_002598"
     CDS             1973..2158
                     /locus_tag="L1V38_002598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317090.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(3062..3337)
                     /locus_tag="L1V38_002599"
     CDS             complement(3062..3337)
                     /locus_tag="L1V38_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBN1317091.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(3309..4262)
                     /locus_tag="L1V38_002600"
     CDS             complement(3309..4262)
                     /locus_tag="L1V38_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1317092.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            4874..6367
                     /locus_tag="L1V38_002601"
     CDS             4874..6367
                     /locus_tag="L1V38_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBN1317093.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            6502..6798
                     /locus_tag="L1V38_002602"
     CDS             6502..6798
                     /locus_tag="L1V38_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1317094.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            6899..7750
                     /locus_tag="L1V38_002603"
     CDS             6899..7750
                     /locus_tag="L1V38_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317095.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            7771..8054
                     /locus_tag="L1V38_002604"
                     /pseudo
     CDS             7771..8054
                     /locus_tag="L1V38_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2928 a         1303 c         1578 g         2613 t
ORIGIN      
        1 tctacataca actattacaa aactattaag aaactgaata ctcctatttt ttgtttttaa
       61 ggaaagtttt ttcttttttg aatttcttat ttttttctaa tataactaag caaaactgga
      121 taatacgaca cttattttca aattttcaca agactaatag taaatatcca tttaataaag
      181 tgatacaatg tgttgatttt acaaatcaac agaagaagta gggaaataac ttacctatgc
      241 ttcttttttt gtacatttaa tcgattcttc tttacaaaaa cgaacgtatg tttgtataat
      301 gtggaagaat ggagtgttat ttatgatgga ttattcaaaa gagccagtaa atgattactt
      361 tttgatcgat atgaaaagct tttacgcaag tgtcgaatgt atagaaagga atttagatcc
      421 attaacgact gaattagtcg tcatgagtcg agcggataat acaggatcag ggttgatttt
      481 agcttcttca ccagctgcaa agaagaagta cggtatttct aatgtcagtc gaccacgaga
      541 tctaccgcaa ccttttccta aaacgttaca tgtcgttcca ccacgcatga atctctatat
      601 taagcgaaat atgcaggtaa acaatatttt cagaaggtat gtagcagacg aagatttatt
      661 gatttactcg atcgatgaat cgatcttaaa agtgaccaga tcaatgaatc tttttacgac
      721 tgaaggaaca agaagtcaac ggagaaagaa gctggctcaa atgatccagg agaatattaa
      781 agaagagcta ggattgcttg ctacagtagg tgtcggagat aatcccttat tagctaaact
      841 tgctttagac aatgaagcaa aacataatga tggattcctt gctgaatgga cgtatcaaaa
      901 tgttcctgat aaagtatgga atattcctga aatgacagac ctttggggta ttggatctcg
      961 aatgaaaaaa agactcaacc aaattggtat catgagtatt aaagacttag ctaattggaa
     1021 tccatacact attaagagcc atttaggtgt gattggctta cagctgtatt ttcatgcgaa
     1081 cgggatcgat cgaacagata tagcgatccc accagaaccg acaaaggaaa aatcatatgg
     1141 taattcacaa gtgttaccac gagattatac caggagaaat gaaatcgaac tggtggtaaa
     1201 agaaatggcg gaacaagtag ctattcgtat caggcaacat aactgtaaaa caggttgtgt
     1261 ccatttatac attggcacgt cgatcttaga aacgagacca ggtttttcac accagatgaa
     1321 gatccctata acagataata caaaggaatt gcagaattac tgtcttttct tgtttgataa
     1381 gtattatgaa ggacaagaag taaggcacgt tggaataacc tatagcaagc ttgtgtacac
     1441 tgattcgctt cagctggatt tatttagtga tccacaaaag caaattgacg aagaaaattt
     1501 agataaaatt attgacaaga ttcggcaaaa atatggtttt acgtcgattg tacatgcttc
     1561 ttctatgtta gaaggcgctc gtagtattac tagaagtaca ttggttggtg gccatgcagg
     1621 cggcgcagga gggcttaaaa atgattgatt ataatgatcg tggacgttta aagtgggcag
     1681 gtttttattt atctgatcat actgaaaaaa ttgatgccga caatgaacaa cgagccaatc
     1741 aaaatttggc aaaagaacaa atgacgactg aagaggttgc ggaagtattg aacgctgcag
     1801 tcataaaaaa tagatcagta tgtattcaaa aagaagaacg aaacgctgaa ggatactatc
     1861 cagaagatat tgttagcaag atcttaggta gtgatgagct ggggatctac gttggaaaaa
     1921 acaaagttca ctacgacgaa atacgtcata tcgaatttta ccaggataat aaatggggtc
     1981 gattagaatg aacattatcc agcaatatga gctaaagtat ataacctttg atcagctatc
     2041 agaagagatt tggggttatg gccagcgttt gataaatgag gttggtgttg aacgcttctc
     2101 tttctatgta gaagctgcag caggatacca taaatacgaa tactatattg gctattaaag
     2161 tgcaataaaa ttatatttct tttatgtttt acattttgta tcaattctga taaaattacc
     2221 tataggtaat taaaaaatat aaaaaaacta gttacaacct taggacgttg taactagctt
     2281 gaagcatact agagctaact aaaatagcac tagaaagcaa tgttaaaccc gtccaacaaa
     2341 cttgatttaa cattgagacc agcttattca gctaaatata gttgaataag cttcttttgt
     2401 tttaaaaaaa caaaaggtgt actacgaata acgcaagtaa aagaaatact attacaacca
     2461 gtaggctaca agtaagtatt actaaacatt gcgtagttag aacctttgct ctattgtcta
     2521 aagccacaaa attagagatc agctttatga tgctaagagc gagctgcatc catgcggaca
     2581 taggttcttt tgacactatt aattctcctt tttaggataa gggaaattgc tagtagtttt
     2641 ttcattagca ccatccccct tcatttgatt gagtctagtg ctgctgtgat agtttgctgt
     2701 ttaatatgct tacattctta ttataacata aatgaaacaa acacatggtt agaggtcgta
     2761 tcaatcaaaa tagtgtctca caaacgattt attacttact cctgctgact aacggactgt
     2821 tcttcagtaa ctgtaactat atgtttgtta aaaccaccat tacctgtaga taaaaaccaa
     2881 tatatttact atactcacta tattaaatat atttagtata gtaaaaacta gaaacaataa
     2941 aatttgtgaa tgttgtatac ccccaaacaa tacacatatt ttgaaggatt aggattaata
     3001 aagctaaaaa tatagtaagt atactaaata tatttactat atctagtata cttactatat
     3061 tttaatcttt tgatcgtcta ttatatataa tccgttcctc gtcgtttaaa gtatcaacat
     3121 aggcgtccat tgcaagtttg actatttcat acataggaat atcttttgca taactaagat
     3181 cccgaatggt ttttagtacg ggaggatcta cttgaactgg ttttctttct ttcgcagtgt
     3241 actttcgttc ccctaactcg acattaatat catctttaat tgaaatatct tcagcaccaa
     3301 ttttcttctt atctttgttc gttggtaata atgccattta gtttaatctc ctttccaaga
     3361 ggtaggatat gattggccat tgagtcagca tatttaggtg tataatcaaa tccttcaata
     3421 tcaccatgtt gttcatagta ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa
     3481 atagcccacc atcttcgatc tacataatca tttaattgga taccattctc accatacatt
     3541 tctaaccgat ccgagccttt aacaatgctt ttaaaaatgt ttgattcacc atacttatca
     3601 attgtttttt gatagtttgc gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa
     3661 attccaatga tttgaagatg agactcttca aaattcgtga caatcggaac taaaacttta
     3721 ttaataaaat cttctgttcc ttccattgcg taccgtttta attcttgcat tgcaataata
     3781 taatctgcag cagttaagaa tgcacgaacc acattatctg ttgatggtgg gcagtcgata
     3841 aagatataat cgaaattttt tctcaattct tctaaaggtt taatgaaggc caatgatctc
     3901 ttacgacgat caggatattt ttcggacaag tattcattaa gttcttcaga tccaggagag
     3961 ccagccataa tatataaatg tggacttact tgagtaatac ctgaaaccca gtcccctttt
     4021 ttgattgctg cagacatgga tcgatcaaag ctagtaattt gatacgttga tccaatgttg
     4081 gaagtagtat ttctttgttg gtcataatca attagcaaca cgtctttttc aaaaagttga
     4141 ctagaaacaa tcgctaataa atcattgtct gtagtcttac caatgccgcc ttttctacct
     4201 gtaagcatta caacttttcc tagtttatct gatgttttaa atgcagtccg taagttttcc
     4261 atagttccct ccaatttcct atactaaata tatttagtat acttcatata cttaatatat
     4321 tcgatatatc taatatactc caaattgata agaattcaga ctttataagg aatatagtgg
     4381 atatactaaa tatatttgct atattcagta tatcagatat attcaaaatg tcaaaatata
     4441 tttgtgcgtt ttgcgttgac aatttagagt gaaaagaggt aaacttaatt ctatagaaac
     4501 cacagataat tcactattta caaagtagca aaagcagtgg tactctttaa acagaaaaat
     4561 tacataaaaa aaagagacgg aaataattga ttttagcaga atcaattatt tctgaatcac
     4621 atggttagga catgtgttca cgctcgtctc aagaatatgt aagtagctac caactactta
     4681 tattaaaagt tgatcggata ccttttccga ttgcctttat tctaccaaaa aaaggcgagc
     4741 aactcaacag aagaacgttt atttagtgta cttaaattaa atattcttaa acactgaaga
     4801 gagaacacat actatggctg agattaaagc taaactgtgt tctctttttg tttgagaaag
     4861 gacgttacaa tcgatgttga gcgaaattta ttcagctatt cttaaaaacg gcttacgtac
     4921 atacaaatat cgaaacagca ccatgaaacc tgcaggtcat attgattcca gtaggagtgg
     4981 tgctatcttt gcgtaccgta gcaagcaatt aatgaatgtt gggcgtggta tggtcattac
     5041 ttcggaagaa gctattttag agaacgaaaa gaaactaacg cattggacac ctaataccta
     5101 tcgctttggt acttatgcgg atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa
     5161 cttaagtcaa atcaacacat ttgtagttga tatcgattca aaagagaacc atcaaggcga
     5221 aattatttta gcctgtttag atcaagtggg ctacatgcca acgctaattt tagaatcaga
     5281 tcatggttat caagtttatt ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa
     5341 tttcaaggtg atcgatgtag caaaaaaaat ttcaaaaaca attcgtctac agttggctga
     5401 aaaattgtcc ggagtggatc taggatgtaa ccacttcgga attgctcgat tcccacaaga
     5461 aaataatatt gtttttaaag aaatgaacta tcagtattct tttgctgact ggattcaatg
     5521 gtcgatgaag cttgaatcag atcaaaaaac aaaagaagat cgagaacgaa aactaattgt
     5581 ctttcctgag aaaaaagaaa ttcgtcaagt agatgaaccg tggttcgata tgttacttca
     5641 taaagcaaac atcgtcggcg gagaaggacg tcttggtcga aataatgtga ttttcacgct
     5701 ttctttagct tattactctt caggttatgc attggatact tgcgaataca atatgttcac
     5761 attcaacgaa cggttacagg aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag
     5821 tgcttattct ggtaattatc aagcagcaag cagagaattc attattgaat tgtgccagca
     5881 atgggtttca ccaaccttaa aaaataatga tctgttcatt caacgacgtg gctggtggaa
     5941 atttaaaaag ccacgagatc aaagaaaata tagtcataaa aatgaatgga aagaagatct
     6001 attggcttat ctaagcgaaa aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa
     6061 agaattggct tcacaactaa cgatgcccaa gcgaacactt gataagatct taaatgagtt
     6121 acgagaggag aataaagtct tctacaaggt aacacgagga agaaatggcg gaatgatcat
     6181 tgcttcagtc aaaacgttgt tcgcgagggt tattcaacta agtaaagaaa agagactaga
     6241 ttattcaaca aggatcacag aggtatttgg actcaacgag agcttagtag aagagacatt
     6301 tagacaatta tcaaccccct tgaaccctct taaagaagtg aatctttttg aagtagatac
     6361 aggttgaaaa ataaaaggtg caaattgcct tatacaatat atctatgata cttctgtagg
     6421 tgttgctccc tttgcctagc tacgtgtagg tggtatactt ataactgcgt atgcagtctt
     6481 atgtatcatg gaggaagttg tatgtcgtta aaaaattatg tctattcaca tcctgttaat
     6541 gtgtttatca ttggtcgttt gggattatct gtggaagtgt tctgtgagct ttatggtttt
     6601 aagcagggga ctttgtcttc ttgggttacc agggaaaaaa cagttgcttc tttgccgatt
     6661 gagtttcttc atgggttgtc cttagcttct ggggagacta tggatcaggt atatgattgt
     6721 ttgtgtgtgt tagagcagga gtatattgag tataaaatag ctaacgagtt aagaaaaagg
     6781 aagaagtata tccagtagta gtttttattt acttaaaaaa ttggttcatt gagcaaccta
     6841 tcgctgctaa agtagcaaag gaaaacgtta aaggaaagaa tttagggaag aaatcgaaat
     6901 gaaatcggac gactggattg aacacacctg gcttcctctg aaaagaaata gcaaacgaaa
     6961 gaaattttgg gtattgcaat tatggccatt aggaaaactt tgtagttacg gggcacgact
     7021 tattcttgat ttaaccgttt actcgattgg agtatttgga acggcttatt acttgataaa
     7081 tgatcccaat aggattgcag catcagacat ttttacagtg ctaatgacgt tgatttttgt
     7141 catgctattg tctattttta ctcaattagt catgcaattt accaggcaaa aattaacagc
     7201 aggaaaactt ttcaaaagcc tattcgattt aattgttgta aatgcaattc tagcgacttt
     7261 aataaaacaa attgaacaat ctggaagaac aacaaaagga gtgaaggatt ttttattgac
     7321 gtttattcac tttgtaaatg gacacatgta tttgtttgaa gtgggtatta ttctcttttt
     7381 tgtcgggtat gtatccacga aacttattaa acgttcaatt gaaaaagaaa ttgaaattga
     7441 cctgattccg acacttcttg gttatgagta caatgttgat tttggaagat atgacgaatt
     7501 gatcaatacg gatatcgttc acacgagtat ccatgaatct actgttaagg gcatcagatc
     7561 tattttaaaa aatggccagg aaatgaaagc aatagatcga agaaaagaga tctacaattt
     7621 ttatgaagtc gaagcaagcc tacgatatgg catcggaaaa ttgtggttag atggaagtaa
     7681 tattcgtcaa aacaaaccat acattttttg gaacagtagt gatttagaac ttccaatgaa
     7741 agataaataa ttatggagaa tcgtttgaaa atgattcctc tatacaggat tgtgcttata
     7801 gttggcatgg agttaaaaac cttaaagaag gagcagttat tcaaagtgaa agaacgtcat
     7861 aatcagttac tatgtagtaa aacgggtacg atgaacattg aataccgaac agaatattta
     7921 gaattaacga atcaaactga ttttttgttg attcgaaagc aacaagagca agaaaaaaat
     7981 taatggctac ttatagccaa ttgattgatg aatgggaaca attcaaggaa tctaaaattc
     8041 cagaacgtct ctaaaagcct ttatttgtaa agagcataag gaaacgtggg aacacttttt
     8101 aaaaaaagtg ttccaatagg ctgtgcctat tacgtttctc aaaaataaat gtgggaacaa
     8161 aatatttaaa aataggatag tgaaaggata gtgaaggata gtaaaaggag ggtagtagga
     8221 tagcaaaaag gataggctcc ttttcgctat cctttttaaa ttggaggaat taatatggaa
     8281 gtaagaataa gaaatgtgga tgagaaaatc gtaagagaaa ttgatcgaag atgtgacgaa
     8341 cggttctgtt gcaaagtttt aaatctacta tcaaataagg tagaataata gaaaaagata
     8401 gcaggaggaa tgacgatgaa tc
//
LOCUS       DAFLWZ010000102         7732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000102 DAFLWZ010000000
VERSION     DAFLWZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.104"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..106
                     /locus_tag="L1V38_002605"
     CDS             <1..106
                     /locus_tag="L1V38_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBN1317096.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(175..903)
                     /locus_tag="L1V38_002606"
     CDS             complement(175..903)
                     /locus_tag="L1V38_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1317097.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(916..2196)
                     /locus_tag="L1V38_002607"
     CDS             complement(916..2196)
                     /locus_tag="L1V38_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1317098.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2337..2939)
                     /locus_tag="L1V38_002608"
     CDS             complement(2337..2939)
                     /locus_tag="L1V38_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1317099.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3184..3390
                     /locus_tag="L1V38_002609"
     CDS             3184..3390
                     /locus_tag="L1V38_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317100.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3702..4421
                     /locus_tag="L1V38_002610"
     CDS             3702..4421
                     /locus_tag="L1V38_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1317101.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4502..5185)
                     /locus_tag="L1V38_002611"
     CDS             complement(4502..5185)
                     /locus_tag="L1V38_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBN1317102.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5404..7590
                     /locus_tag="L1V38_002612"
     CDS             5404..7590
                     /locus_tag="L1V38_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBN1317103.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2775 a         1301 c         1460 g         2196 t
ORIGIN      
        1 aaatgaaagt caagaagtat tgctgaaaga aatggagaat tggccaacat tttatccaga
       61 tacaatggat ggacgtgaaa ttgcacagga aatgcttttg cactgatagg caaaaaagaa
      121 ccgaagggtt tggatcggct ggtcatttag tcggtccaaa ctattcggtt ctttttatga
      181 aatcaatttc tttaatccac ggatagaggc tgggatggtc tcgccgtttg ccaacgtgac
      241 ttctctggtt tttttattaa tcgaccgcac attttgtgta ttgataacat aggatttatg
      301 acaacggata aaattccgat gcattttctc gatttctttg atcttctcat agaattgtaa
      361 ttgggcatga gtcaaatgga cttccagttt atgtggcgct cctagcgaag tagaaaaata
      421 ttggatgtct ttgatcggta aaaatttgat ctcatcatta aactctattt tgaagatatc
      481 tttttggatt tgggacattt gaaaatcttc gaaaattttg ctcaggatat gctcgacatt
      541 ttcttttaaa tcataaagat cttctttgac gatataatca gtcggttcga tgttgctttt
      601 taagattttc atcgacattt ccgtatggga agtcacatag attatttttc ctaaaggatc
      661 taattcacgg atcaatttac cgatcgctac accatccatt tcactgtctt ctagttcgat
      721 atctaaaaag taaataccaa aagaagaagt tctgatcttg gctgcattga gaagttcttc
      781 cggatcagag gtagaaatat ggacataact gtctaagttt tcaatcatga ttctattttt
      841 gatcaccgtt gataaaactt ctaattgttt tggatcgtct tcacaaatat aaatgggaat
      901 catatcatta ctcctttatt ttatttgtat ataaatcgtt tgagaaaaac gctggttttc
      961 aattgatgtt tcaaggaaaa gataaggatt ggtctttgtc aattcatcca agataaacaa
     1021 gccaaggcct tcgttttttg gatttgtttt tgttgagaac cctttttgtt tcaactggtt
     1081 taacggtaat gtatttgttg ttgtattgat cacacgaatc atcacggaat gattcttctt
     1141 gagtatggtc aattcgattt ttttcttctt tgcagcacta gctccttcaa tcgcattgtc
     1201 caagataata ccaagcatac gtacaaggtt taccgtatgt ttcgtatcca gttcgattgg
     1261 ctcaggaaaa tgaagctgga cgatcaaccc tttttcctgt gccatcatga gttttaatga
     1321 cagtaaacta cggatctcag gaactttcat attatccaac atacttagat tggccggaaa
     1381 aaggttcatc atctggcgtg taggtaatat cgtttgatca taataagacc gtaatccttc
     1441 taagtcgcct tctgaaatat agctgtgaag agaaaaaagc agattttggt aatcatgttt
     1501 gaattctctc aagtcttgat agtttttttc tagatctttg atataatcct gttgcatcct
     1561 gacttgttgc tctaataact gatcagctaa tttcttatta gagattttcc aataataaac
     1621 caagatgatc aggccaacac acagatatag aatgaaaaaa ctcgtattca aagctaagac
     1681 atcaggtgtt tcaccagaaa aacgggtata aaaaataatg atatagtatg taaataatat
     1741 caatgtcccg atcgtaccga tcatacggcg gtccacagtg tgaaaccaag tctctaacga
     1801 tttttttaaa caaaaagcta ataaagcaga taaaaaagcg gataagacaa tgtgaaaata
     1861 ctgcaatgaa tctcctggtt caataaccga agatttcaaa acaaaaaaat cgccgatgct
     1921 tgttaagtga tctcctaaaa gcgacgtcaa taacccaaaa ggaagcgcgt aaaccaattg
     1981 ttgacgcgaa gtcgaaaaga agaaaaaagt aagcatcagc attcctatag caattagagc
     2041 agtaaaaatc cctaaaatcg aatagaccca tccaatcaaa atacaagaaa tcagaatgac
     2101 tcccgcaaac agatatttgt atcggatgtg atggtcaatc aataagatac aaattgtgta
     2161 aatcaaatat tgcaacgcta tggaccataa aaacataaag tacagctccc attgattttt
     2221 accaaattat agcacaattg gcgtattatt tttttaattt ttcagggatt ttgaattcag
     2281 aactcatacc aaagcagcag ccagatacaa aaaagtcaga taagttagtt aattgtttaa
     2341 tgattgtttt tttcatgaaa gattcctcca aaattcatca agtagtttgt aataggaagc
     2401 aacgtagcta tttctaaaac aatcccaagt agcaaatagg tagaaaagta agaagctgag
     2461 aaaaataacg taatgagaga aaaaattaga aacatgctga tcgccttctt taataatggg
     2521 ggacgtttct cgggttcaat gggattgatt gctgtacctc ttgatccata gcgaagcagt
     2581 aacaaaaagc agctgattaa caaaaagacc atcattggga aggagatagt caattgcaga
     2641 tgtttcatca ccaagggaac gccccataaa taaagtagtg tccacagcag acaaacgaat
     2701 tcagagtcgg aatgcaatcc ataagcatat ctgcggatgc agatataaga aagaaaggtg
     2761 attcctgttt ccgcccatga gcctgtcacc agagaaaaga ctagaacgac cgctagtttt
     2821 ccaagattat tcaataaaac ttctaagaca aattttactt ggacatacac catatcttct
     2881 tccgatttgt ctccgctgaa taaggcttct aataatttgt tcacaacttt atctttcatc
     2941 tcatacgtac ctccaccaca aattttatgc taaaaaaaat aaaaaacgtc ttttgtttca
     3001 taaaaagtgg ttttgacatc aaaaccgtca tgatctccta aaaaaatctt cgttttccaa
     3061 gaaccttacc aaaaaaagtg acagttttga tacgaaaagt actttttatg acaagtttgt
     3121 gctttttcga gtgatttatg ttaaaaaatt actgacctta taaaaggtga tggagggatt
     3181 cttatggaaa atgaacaatt gtttgaagtc ggcgaaacat atgcatttaa atctgattta
     3241 tttgaatcac caataaaagg aaaaatagaa aaaatctatg aaaatagtgt gatgatacgt
     3301 gtcatgaaat gcgcagtaga agacaatgat accgctcata atctgcactg gcagttagtt
     3361 gtacgcaaat caagtacaat agaagaataa aaacagataa aatgttgaga gcataaagag
     3421 gttgtgagtc tcccgtttag ctctgagtta caaggaataa tgttaaaaaa cagcttttca
     3481 tgttttatga atattgcctt gtgaccgagg tgttggcagg agaatactgt ttatttgaaa
     3541 aaagggctgc gacaagactt ttgtcacagc ctttattttc atgaatagga gttacttttg
     3601 gctactttta gagaagtagc ttttaaggag cagataaagt caaggctttt atttctataa
     3661 atgaagtagt aaaatgaaga acagatttta ttacaggaag gatgccgata attgtgatca
     3721 ttgttgcagg aacgatcggt gcagggaaaa gcacactaac tgaaatgctt gcccaagatt
     3781 tagaaacaaa acctttttat gagaacgtgg aagataatga agtattgccg ctattttatt
     3841 ctaatccaga aaagtatact tttttattac agattttctt tttgaacaaa cgctttttgg
     3901 caatcaaaga tgctttcagc catgatgaca acgtactaga ccgctccatc tacgaagata
     3961 gtatgctgtt tcatttgaat gcagatttag ggcgtgtttc tgaagtagaa gtaaagcagt
     4021 atgaaggtct tttagaaacg atgctgaagg agttagaaga aatttcgcca caaaagaaac
     4081 cagatctact ggtttatatt cgtgtatcct ttgaaactat gttagcgaga atcaaaaaaa
     4141 gaggccggga atatgaacag ctagaacaag atcctgaact ctattcctac tataaagaac
     4201 tcaatcgacg atacgaagag tggtatgaac agtttgatat atgtcccaaa atagtgatcg
     4261 atggggacaa atatgatttc gtagccgatc cggcatgtgg agaacaaatc gtacaagaaa
     4321 tcaagatgcg ggcaaagaaa atgacagaag aggcagatgc ccagtcgatc cgctacacta
     4381 caaataaccc gaaagcaaag ggaatcttta caactaaata atataaaaac taagcaaatt
     4441 gctcactcgc agatatttct ctgtgagcag catcttgctt agtttttttg attcattgag
     4501 atcaaatagt gaaccgattc gtatgataaa attgccataa atgaaatgtc tgagtgaggg
     4561 ccatgatcaa aaataaaatg gaaacgatca aaatcgaatg ggcgccaaac agatgatgac
     4621 agaaaacaag gacaatagct cctgcgataa aggcaagaac gacacttaga tagtggaaaa
     4681 atcgatcaaa atctgctttt tctttagaaa tacaataatc atataagttc gttgctaccc
     4741 cttttaaatt tccagttgta aataaattag tgtaggcacg cccgttgatt ttatcaaaag
     4801 ctacccactg gatcgatgca gtaaaagcaa tcaaaatcgt tactaatgcg ggatgctcat
     4861 ggacgggtgt caaactaaca aagaaaaaaa tcactgcttc ataatataga acaaacaagc
     4921 gccagaaatg tttttctttt tttctaaaat aatcaattag atactttgtt agaagaatcc
     4981 ctaagaaaaa gaaaagggta gacaatactt ttttaccaac acttagccat tctccgtcaa
     5041 atgcttggat gatcgataga atgatattgc cagtttgagc agaggcaaaa gcaccatatt
     5101 ggatataagt ataactgtcc atggctcctc cgataaatgt cagcaaaagt cctattgtac
     5161 gcccctcgtg aaaggaagtc tgcatttttt tcatcacctt ttatgaatat ttttgtcttc
     5221 cttatcttag cataaacgat tgaaaaaaaa ggaaaaattt tcagaaaact aaaatcatat
     5281 cgcttcccat tttcattttt agaaaggtct gttagtataa agaaaaaata gacaacgaaa
     5341 ctttaaataa ccaacttgaa ataaacaaat tcaaagaaga aagatgggaa ggaaatcaat
     5401 cagttgaatg aaaaagaaat tctccgatta caaaaagaat tgaaacgctg ggagaacaag
     5461 tataaaaagc ttcaacaagt ctttcggcta caagaagaaa tcattgctac ctatgaagcg
     5521 gcttatggcg aagcacccgg acttattgag gaagaagtac aagtaaaaga aagtgaagga
     5581 aacagctctt tctttaaaat gatggagaaa cgttcctata atcgcttcaa tcaagaacaa
     5641 aaagcagcta tcacatatga tatgaagaaa catcttcgaa tcatagcagg agctgggagc
     5701 ggcaaaacgc aaacaatctg tgcaaaagct gtttatctga tgacgcaaaa acaagtagac
     5761 gaagaacgca tactaatgat cacttttaca aggaacgctg caaatgaact aaaaaaacga
     5821 gtagataatt tcagccagag aaaaaccgct gtccatatcg gaacattcca tagtatcttt
     5881 tttaggatat acaatgaaat ttgtcgaaaa tttcctgaag tagcaatgca aggaatacaa
     5941 ggagactttt caaaggatac tgcacaaaaa gtgaatgctg ttttgcaaca gctgatacgt
     6001 aaatataatc tttatatatt tgatcaatat ggagaaaaaa cgattgcttc tcggttagac
     6061 tattggcaga atatgaacct ttcagtagaa gaaatggttc agttagttaa agaaaaatat
     6121 gattccattg ataagaatgc acgacagccg atatcagaac gactgtatgg attgctcacg
     6181 gaactccaag aacaaaaaag aagccagcaa ttgctagagt tcaatgatgt actccaaaat
     6241 ctgaaaagcg ctttggagaa tgaggagatc cagcattata tcggccaaaa atatgattat
     6301 ctattcattg atgaatttca agatactaat ccacttcaat gggaaatcgt gaaacggatg
     6361 acaaaggaaa acaggatcaa gttgattgtt gttggagatg atgatcagag tatctatgga
     6421 ttcagaggat cagagccagc atacatcaag aactttgaaa aagaatatcc taccaaaact
     6481 cttttcttat taactaatta tcgttctcgg gcagctattg tccaaggagc aaatagattg
     6541 atcagctata ataaaaatga tcggatacca aaggcgatga ttccagcaca aaaagaagca
     6601 ggtgttatgg aagcctattt gttttctgat actaaagcag aaagtcagtg gctaatcaaa
     6661 caaattcaga catttattca aaaaaatggg aaatataagg aatcaatcat attataccga
     6721 tcagcttcac aaacgcagca gcttgtccaa tctctgctga aaacgaatat tccttttgta
     6781 ctggaagcag atagtccata tgaaggtatc tttggtatca agtctttcca acatttctat
     6841 caaaaaattg ttcattggca aacagcactg aatctgcaaa agaaaaatca ggcctaccag
     6901 caattgctcc ggcagctgat ggcagactgc tacctgaaaa aaagtgaatg cgatcaatac
     6961 ttttctccta aatatcaaaa tatagccgtt gcagattata ttttgtcgat aagccccaat
     7021 ttaaaatcga aatctgcaga aatccgagag tttgaggaag cgttgcgtaa aacagaccag
     7081 catcaagaaa tctattcgct tgttcaaagc tatcttcatc tgccacgtat agctaaggaa
     7141 atcgaccaga gtgatcaaga atggatacga gaagaagtaa agcagcatgc tactttcaga
     7201 agactccaag ccttatcgca agaaacccaa gcgacagcta aagaattaaa aacccgcttg
     7261 attgcttaca gacaaggaaa acttgatgca ctatgtatcc agagcattca caaaagtaaa
     7321 ggtcttagtt accgaaatgt ctttttgatt ggttgtaacg aaggaagttt gccttataac
     7381 ggagcgacag aaaagaaagt aatcgacttt aatgaaataa aagcagaacc agtaacgacg
     7441 atagaagaag aacgaagact attttatgtt gcgatgacta gagcaagaaa tcgtctgtat
     7501 ctatgtgtac ctcaaatgaa aaattcaaga aaattgaaag tatcgagatt tatcaaagaa
     7561 accgggagtc gtgtgaaaaa aggaaagtga tagaagagag ggtgtgacag aagtggtcag
     7621 tttcaagaaa gaagaaggaa tgtacgaaaa ttgcttctca aatttttgtg aaatttcagc
     7681 ttattttcga agaagctatt tctggaacac agtttattcg gaaaagggag gt
//
LOCUS       DAFLWZ010000103         7600 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000103 DAFLWZ010000000
VERSION     DAFLWZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.105"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(943..1356)
                     /locus_tag="L1V38_002613"
     CDS             complement(943..1356)
                     /locus_tag="L1V38_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBN1317104.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="L1V38_002614"
     CDS             complement(1812..2297)
                     /locus_tag="L1V38_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317105.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="L1V38_002615"
     CDS             complement(2436..2651)
                     /locus_tag="L1V38_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBN1317106.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="L1V38_002616"
     CDS             2875..3675
                     /locus_tag="L1V38_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1317107.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="L1V38_002617"
     CDS             3694..5562
                     /locus_tag="L1V38_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1317108.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="L1V38_002618"
     CDS             5555..6046
                     /locus_tag="L1V38_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBN1317109.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="L1V38_002619"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="L1V38_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBN1317110.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="L1V38_002620"
     CDS             6606..>7600
                     /locus_tag="L1V38_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBN1317111.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAFLWZ010000104         7391 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000104 DAFLWZ010000000
VERSION     DAFLWZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.107"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V38_002621"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V38_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1317112.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="L1V38_002622"
     CDS             complement(1804..2697)
                     /locus_tag="L1V38_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317113.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V38_002623"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V38_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBN1317114.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="L1V38_002624"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="L1V38_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBN1317115.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V38_002625"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V38_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBN1317116.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1976 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc a
//
LOCUS       DAFLWZ010000105         6820 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000105 DAFLWZ010000000
VERSION     DAFLWZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.108"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            102..464
                     /locus_tag="L1V38_002626"
     CDS             102..464
                     /locus_tag="L1V38_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317117.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            481..1092
                     /locus_tag="L1V38_002627"
     CDS             481..1092
                     /locus_tag="L1V38_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HBN1317118.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(1194..2102)
                     /locus_tag="L1V38_002628"
     CDS             complement(1194..2102)
                     /locus_tag="L1V38_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1317119.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(2144..2458)
                     /locus_tag="L1V38_002629"
     CDS             complement(2144..2458)
                     /locus_tag="L1V38_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1317120.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            2757..4688
                     /locus_tag="L1V38_002630"
     CDS             2757..4688
                     /locus_tag="L1V38_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1317121.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            4981..5532
                     /locus_tag="L1V38_002631"
     CDS             4981..5532
                     /locus_tag="L1V38_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317122.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            5845..6387
                     /locus_tag="L1V38_002632"
     CDS             5845..6387
                     /locus_tag="L1V38_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317123.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         2224 a         1142 c         1315 g         2139 t
ORIGIN      
        1 aattgcttat aatagtgtat tgaaattaag gtagattgac aaacgagtga tcaaatagat
       61 atactacctt caaacgaccg tttgaatgtg aggtgagatg aatggaaaaa gtttgccaag
      121 tgactatcgt acataaagaa aaagtaaatg taataaaaaa aaaattggat caaaaagatt
      181 tttcaaactt acttgtgtta gggaaatgtt tcagcgattc ttctaggatt aaaattttct
      241 atgctttaga aacctataag gaaatgtgtg tctgtgattt agcagaaata cttactgcta
      301 gtgtcgctac aacgtcacac catttacgtt ttttaaaaaa acatggaatg gcaaaatcac
      361 gtcaagatgg aaaagtagtt tattattctt tagcgaatga agacatcctt tccgctattc
      421 gtgttttttt aaagttatca gaaaatctat ctatgaaatc ttagtttgga ggaagttatt
      481 ttgttacaaa gtattttttc agctatcgct gtttatattt ctaccagtat tgattatttg
      541 tttatcttgc tgattatctt ttctcaaagc cacacaaaaa aaggtattcg tcacattttt
      601 tggggtcaat atcttggaac aggtattttg gtagccgtaa gtttgtttgc tgcttatgtg
      661 ctaaatttta ttccgcaaga ttggatcatt ggtcttctcg gtctaattcc gattttctta
      721 ggaatcagag tcgcttttgt tggcgaagag gaggaagaag aagaggaagt cgttgaaaaa
      781 ctcgaatcta gaggaactaa tcgcttattc tggacagttg ccttaataac gattgcttct
      841 ggaggcgata atttaggtat ttatattcca tactttacct cgttagcttt ttcagaaatc
      901 attattgctt taatcgtatt cgctatctct gttgcggttc tctgctatat cagttacaaa
      961 ttagccaaga tttcttttgt ttccgaaacg ttagaaaaat acgaacgaat cattgtccct
     1021 ataatgttta ttgcgttagg aatttttatt atgatagaga acgggacgat acaaacgcta
     1081 ctaggttttt aaaaatcata atcacgaaag ataaaaagag aggcagcgac taatcaaaat
     1141 cgctgccttt tttgcttttc aaataatgaa gtatttttta gcgtagaact atcttacgtg
     1201 ttgtgggagt atcccttttc aagctcttct ttgcttgtag ttatttctat tgtgatatga
     1261 ttctctacgc ttgatttgtg tgcgacttct gcaatttctt cttttatttc cctagccttg
     1321 tctatgtctg aagggtctat aagaaccgtg atgataaggg cgttttcttc cccgtccagt
     1381 gaccaaatgt gaaaatgtga gaggtctttt acagcaggaa catttttaat ggagtccgcc
     1441 aagctcttta cgtttacatt ttcaggcgaa ccattcaata aaattttcat tgtggtgaaa
     1501 aattcaggaa cggttttgta gaggatataa agtgcaatca aaatcgataa gataggatcc
     1561 agacgatatg cctcggtaaa gttcattaga atactcacaa tcaagactcc aatccaccct
     1621 aatacgtctt ccagcatatg gaggttcaac atgctctcgt ttttggatgt gcctttgctt
     1681 aaaatccacg cagcatatcc attcaatgca atagctacga gagaaagcca gaacatgcca
     1741 ctataattta cgggttgtgg gtcaatcaaa cgtggcacac tacgatagat cataaaaaac
     1801 gagccactaa ttagcacaac gccagttatc agcgcgccca gtaaagaaaa gcggttatag
     1861 ccaaaagtga accgttcatc ttgttttttc tctgaataac cttgaaaaaa ccaagcgaat
     1921 ccaattgaaa tagagtcccc taaatcatga actgcgtcgg acataatgga cacactattg
     1981 aaaagaaagc caaagaaaaa ttcgcttata gagaaaataa gatttatgaa gaaagcaatt
     2041 ttaatattct ttttcggttg attctgattc gagtgattat ggtctttatc tgattttgac
     2101 atttaaaaac ctcctaagtt tgtatgctac atactaattg gttttatttt tctaattcat
     2161 taacatgagt taagacttgt tcgagaatac taaaaacatg aaggtcatct aaactgtaaa
     2221 gcatactttt tccttctctt cttgatttca ctaagcgtgc gtctttcaac gtttttaatt
     2281 gatgagaaat agcggactgt tccatgtcca gagaaatagc gatatttcca acactacact
     2341 cttttttctg taaaagaaag agaaccgaca atcgtgtagg atcactaatc accttaaata
     2401 gtttgcttat tgacagaata gatcctttat cgattggaga agttgttttt atatccatag
     2461 tgtttttatt cctttcatat gaccttccgt tcatatctat attaccatat gagcgaaaca
     2521 atgctaatct tttgtttata aaagagaagt ggcgttctct ttatcttgac aaaatgtata
     2581 tagcgatata aaatgagtat acaaacatat gattaattag tcatatgtaa ggtggattca
     2641 ttacgattta cttttggaat aaacgaaagg agtcagaaat agcagaaatt tatgtgattc
     2701 aagaagtaaa tgatggaaaa caaaggaatt ataaattata tagggaggca atagaagtgg
     2761 aaactatcca agaacaacag tctcaagaaa agcataatca taatcacaac cacgatcacg
     2821 accatgatca tgggaaaatg ccagtcgttt tgtactttgt tggtttagca ttagcagtga
     2881 ttgctctatt tttgaatgaa gattatcagt tggtacaaaa tgttttgttc tcaatcgcta
     2941 caatcagtgc cgggtatcac gttattcttc ttgaaggcct tggagaaaca attgagaatt
     3001 caaaagcaca aaaaaagttc atacctaatt ctcatatttt aatgggatta gcggcaattg
     3061 gagcttcttt gatggggaat ttttgggaag gaacattatt gattcttatt ttttctggcg
     3121 cacatttttt ggaagattat gcagaaggaa gaagcaaacg agaaataacg aaattactcg
     3181 aaatgaatcc aacgactgcc cggttaatcc tgcctgatgg tagtacaaaa aatgtggatg
     3241 tcagtgaatt aaaagtggga gatcaacttc aagtgttgaa tggcgatcaa gtacctattg
     3301 atggcgtcat tttgtctgga tctacatcca ttgatgagtc gtctattact ggagaaagta
     3361 tcccgaaaga gaaatccaaa ggagatggcg tcttcgggag tacaatcaat ggaacaggta
     3421 ccttcacgat gaaagtcacc aaagaaaaca aagatacagt attttcaaaa attttacaat
     3481 tagtgaatca gaaccaagat aaccaaacaa aagctgcgag tattatccaa aaatttgaac
     3541 cgaaatatgt cacagttgtt ttaattgcca ttcctctatt catgttattg gctccttttc
     3601 tacttgattg gacatggtca caaagtgtct atagaggatt ggtcctttta gttgcagctt
     3661 caccgtgtgc tttagcagca gctactgtct cggcaacgct atcgacgact tctaatttag
     3721 ccaaaaaagg agtcctttca aaaggtagtt cttacctgtc tcaattagcc gatattaaag
     3781 caattgcatt tgataagacg ggcaccttga ccaaaggaaa acctgaagta accaattatt
     3841 attttgctga ttccgtgaac gaagaaaaca tgattgatat cgtagtagct cttgaaaaag
     3901 aatccaatca ccccttagca gatgctattc taagaaagtt tgagcaaaaa aacaaactaa
     3961 ctattgaagt agaaaaccaa attggtaaag gattgacggg agattacaaa gggagaaatt
     4021 atcgtatagg aaaaccgact tcgtttgatg atgtttcaga tgaatatagt cgtttaaata
     4081 atgaatgggc gtcagaaggt aagacagtcg tatacgtagc agtagatgaa gaggttatag
     4141 gccttattgc ccttatggac gttccgagtg aatatgctaa agaaaccatt gaatatttta
     4201 ggaaacaagg tatacacacc acattaatta ctggtgactc agaaatgacg ggaaaagcgg
     4261 ttgctaaaca attaggaata gatgaagtga ttgcgaatgt catgccggaa gacaaatcca
     4321 gaattataga cgaacaaaaa gaaaaatacg gcgtgaccgc catggttgga gacggtgtaa
     4381 atgatgctcc tgctcttgtt aatgcagatg tgggaatcgc tatgggagat gggactgatg
     4441 tggcagtaga ggtatctgat ttagttttaa tgcaaaacaa tttatctaaa ttggtacaat
     4501 ctcataatat ttcttcgaaa atgaaccgtg ttatttggca gaatattatt ttttcaatgg
     4561 ccgttgttgc ttttttaatt gtcgttagtt tcttaggctt aacggatatt gcaatcagtg
     4621 tcattattca tgaaggaagt actttggttg ttattttgaa tggacttcga ttgctaaagg
     4681 cagtctaaag aatgattgca caacttcaaa ttaatcgagt aatagagata attaaggatt
     4741 acactacatt ttttatctct attacttgtt tatatttatc tagatgttca aagtcaaaat
     4801 gatatatcaa ccatactctt gtggcgcggg ttgaatataa gatacatgaa attggataaa
     4861 atcatgtatc aagaatccta tccttatagg gttctttttt tttactcccc ctaaacacac
     4921 gatttcgtgt tgtaataact ataatcatgt attcgaacag actaaaaagg agggattgtc
     4981 atgggctata atgttcagcc actacggtcg caacaggaga ttaatgattt tttattttgc
     5041 ctgcgacgga ataaaaatgc ggaacgtgac gttttcttgt ttctaattgg aattaacagc
     5101 ggtctgcgca tgtccgacat cgttaaactc aagaaaaaag acgtgattac ctcaaaaaac
     5161 ccgcgcatcg tggagcaaaa gacagggaaa acacgcattt tatacttaag cagcttacag
     5221 gacttgattc acggctatac cgcaccctta gatccggagg cttacttgtt tcccagtact
     5281 aagggcggcc atttagaagt caatacggtc taccagatgt ttcaaaaggt cgcgaagctg
     5341 ttaggaaggg acgatatcgg cacccacacc ctacgaaaaa cctttggtta ccactattac
     5401 aagaaaacca aagacgtggc caccttaatg gaaatctttg gtcacagcag cgagaagatt
     5461 accaaacgct acatcggaat taatgaagat gaaatcagtg aaacgttatt aaattttcgg
     5521 ttaggttttt gattgtatta tataatagat aagcacagta agacggttat aatcacccac
     5581 agtattggac aaatcaacct ttttttggta tattatatat acaaatgaga gcaggctcat
     5641 agtcaacttg atataaatcc ggaacataag ggtccggcgg gtggcgagca ccaaaactaa
     5701 actcgataca aatccggaac gtaagggtcc ggcgggtggc aagcaccaaa actaaacctg
     5761 tacaaaaggc tgctcttttg agcagctttt tttattggga aaaaggagca ttcttcgcac
     5821 gcggcaaaaa aagaatacaa acgcatgtct ataaaagaga caacccaaat taccagacag
     5881 ttaaacgcga tttataaggc tgctcatctc ttacaagaac attttgtaga taaaaaagta
     5941 tcctttgtcg gagaagtctc aacggtagcg attatttttt cgacaactaa ttttatgcac
     6001 ctctgtggca ttgattatcg cagaggcaca cacttgtttt ttcaagatgc cttagacagg
     6061 aaaataaatt tacaggatat tcaaatcaaa acggatggga cgacctttca gaaattacaa
     6121 gtaataggta gccttgattt attattgggg aagcatattt ctattgttgg cagaggtgtt
     6181 tactcttctc ttcgctatga tgcagctatt cgaacaagga aaaaaatatt ggctctgtct
     6241 ttgaaacaaa acggattaat ctatatccct atctctttgt taaacctatc atcaaaggaa
     6301 attggacctg gacaaaaagt tactggcatt tttagcgagg atttaacatc cggggaactt
     6361 aaaatgatta tggaagtcat cgattaatca ttaatagtga tatgcgacgt cattttgaag
     6421 taattattct attttgggtt ataaaataaa gcattttaag acgatttcaa atcattcatg
     6481 tgggttattt atcacggatg agcttgaaat cgtcttttat acgtatcaaa ttgaaatgtt
     6541 cggcatacaa cctatcgttg ttactacatt actaattgtc acttgttaag gaacttggat
     6601 cctttctaaa cattccctag agataaattt tactttatcc ctccgttaat atccaattta
     6661 agcacctttc cgattcaggg ttaatttgca tatcaagtgc agcttgtgtt ctagtaagat
     6721 tagccctttt agtccggctg agttgactta tggatataag atatggtcat agcaaataga
     6781 tactacgtat agtctgttaa tttagtgtca ttaatcttaa
//
LOCUS       DAFLWZ010000106         6760 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000106 DAFLWZ010000000
VERSION     DAFLWZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.109"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(118..576)
                     /locus_tag="L1V38_002633"
     CDS             complement(118..576)
                     /locus_tag="L1V38_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1317124.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(589..1920)
                     /locus_tag="L1V38_002634"
     CDS             complement(589..1920)
                     /locus_tag="L1V38_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBN1317125.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1931..3373)
                     /locus_tag="L1V38_002635"
     CDS             complement(1931..3373)
                     /locus_tag="L1V38_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1317126.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3360..4124)
                     /locus_tag="L1V38_002636"
     CDS             complement(3360..4124)
                     /locus_tag="L1V38_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBN1317127.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4228..5103)
                     /locus_tag="L1V38_002637"
     CDS             complement(4228..5103)
                     /locus_tag="L1V38_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1317128.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5358..5442)
                     /locus_tag="L1V38_002638"
     tRNA            complement(5358..5442)
                     /locus_tag="L1V38_002638"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5406..5408),aa:Leu,seq:caa)
     gene            complement(5460..5531)
                     /locus_tag="L1V38_002639"
     tRNA            complement(5460..5531)
                     /locus_tag="L1V38_002639"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5497..5499),aa:Gln,seq:ttg)
     gene            complement(5541..5613)
                     /locus_tag="L1V38_002640"
     tRNA            complement(5541..5613)
                     /locus_tag="L1V38_002640"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5578..5580),aa:His,seq:gtg)
     gene            complement(5675..5759)
                     /locus_tag="L1V38_002641"
     tRNA            complement(5675..5759)
                     /locus_tag="L1V38_002641"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5723..5725),aa:Leu,seq:caa)
     gene            complement(5780..5850)
                     /locus_tag="L1V38_002642"
     tRNA            complement(5780..5850)
                     /locus_tag="L1V38_002642"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5816..5818),aa:Cys,seq:gca)
     gene            complement(5896..5967)
                     /locus_tag="L1V38_002643"
     tRNA            complement(5896..5967)
                     /locus_tag="L1V38_002643"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5933..5935),aa:Gln,seq:ttg)
     gene            complement(5979..6051)
                     /locus_tag="L1V38_002644"
     tRNA            complement(5979..6051)
                     /locus_tag="L1V38_002644"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6016..6018),aa:His,seq:gtg)
     gene            complement(6054..6127)
                     /locus_tag="L1V38_002645"
     tRNA            complement(6054..6127)
                     /locus_tag="L1V38_002645"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6093..6095),aa:Trp,seq:cca)
     gene            complement(6134..6214)
                     /locus_tag="L1V38_002646"
     tRNA            complement(6134..6214)
                     /locus_tag="L1V38_002646"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6178..6180),aa:Tyr,seq:gta)
     gene            complement(6216..6291)
                     /locus_tag="L1V38_002647"
     tRNA            complement(6216..6291)
                     /locus_tag="L1V38_002647"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6256..6258),aa:Phe,seq:gaa)
     gene            complement(6327..6399)
                     /locus_tag="L1V38_002648"
     tRNA            complement(6327..6399)
                     /locus_tag="L1V38_002648"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6364..6366),aa:Asp,seq:gtc)
     gene            complement(6409..6481)
                     /locus_tag="L1V38_002649"
     tRNA            complement(6409..6481)
                     /locus_tag="L1V38_002649"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6446..6448),aa:Val,seq:tac)
     gene            complement(6497..6568)
                     /locus_tag="L1V38_002650"
     tRNA            complement(6497..6568)
                     /locus_tag="L1V38_002650"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6533..6535),aa:Glu,seq:ttc)
     gene            complement(6583..6672)
                     /locus_tag="L1V38_002651"
     tRNA            complement(6583..6672)
                     /locus_tag="L1V38_002651"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6636..6638),aa:Ser,seq:gga)
BASE COUNT         2041 a         1490 c         1100 g         2129 t
ORIGIN      
        1 attcgataat taacaaaaat caaaatgatt aaatctagtg attgaaacat atcatttcaa
       61 aaaaattttg taaattcacc cataaatatc accctattta acttttttca tcgtacacta
      121 aaattcaaaa caactatctt taatctttac ttcttggttt tgttttaata aatttccttc
      181 aaaaatgcct ggagaaacta caatgatcac cgtatctttt tgtgcttgct ccaacttctt
      241 caaatctata atagctaaca gtgtcccttc ttttacctcc tggttacttt caacccgtat
      301 ctgaaacgga cttccttcga gttcaactgt atctaaaccc atatggatca gtatttttct
      361 gccagattca ctttcgatcg ttatggcatg tcgggtagga aatatattat cgattattcc
      421 tttaactggc gcatggatat atccatcatg attcgttata gcgtatccaa ctcctatcat
      481 ttttgaagaa aagacctcgt cttttactgc tgttaatgga ataatttgac cactagctac
      541 agcttttaga atgtttcttg ttttaaagaa atgcactttt tatcacctct actttaatgc
      601 tggccaatat tttttgttta ctttgatcat ttcatctagt attttttttg cgactctggc
      661 atttggtacg gtttgattca atgtaaatgc ttgtaaagct ttttgataag aaccttcaaa
      721 gtaagcatct actagtaact tctctactgc aacttgtgcc tccatcaatc ctttatgaaa
      781 atcactgatt ggttttctta gtgtaattgg ctccacacca gttgcaccaa catatgccgg
      841 tatttcaaca actgcatctg accgtagatt cggaatcgcc ccttgattag gaacgattag
      901 cataaagcga cgacgatcat cattcaacaa ggaaatagct atatcgacga tatattgtcc
      961 atgctcccca aaattaaagt tcaatacttc ttccacaata ccgcggcgta ttttatcagc
     1021 catttctttg gtatttttct ctcgtccatc catgaccata ttagcacgtg tatactcttt
     1081 gtcagtatgc tcaacgacca tatcaggata taagtaatac tctaagtaat tattcgggat
     1141 attacttgga aaatttttcg tgatgactga catcatttga aaggtttttt gccaagtttt
     1201 atctcctata ttaaaatcgg cgacttgcat ttcttttgtt attagttttt caataatctc
     1261 tggcataatt tctcgttgca attctttatc ataaatcgat gtataccagc caaagtggtt
     1321 taaaccataa tacgtaacga tccaattctt acgatcataa ccgtaattca ctgcaatcgt
     1381 ttcttcaatt gaaatagtca tatcacaggc attaatcatt tttacattcg gatatttacg
     1441 acgaacagct tcagaaacga tcgactctgg atttgtataa ttcaaaatcc atgctttggg
     1501 ggcatagtct tgtatatgat cgacaatttc caataaacct ttgattgagc gcatcccata
     1561 agcaaatcct ccgagtccac acgtttcttg tcctactaat ccatgtttaa gtggaatctt
     1621 ttcgtccttt tctcgcatct ccaatcctcc aacacgaatt tgtgagaaaa caaaatcgca
     1681 tcctgtaaaa gcaagctttg gatcatccgt tgcacgaatg cgaatatttg aaaaaccttt
     1741 tcttttcagc ataaatttaa caatcaagta catatccata tttctttctt catcaatatc
     1801 atataaacgt atttcagata atggcaaccg tttttcattg ttcaaaatgg cttgaacgat
     1861 tcctggtgta tacgtactcc cgcctccagc tatagtgata atctgttttt tcatcatcat
     1921 cttttccttt ctattcttct aataatttat tgaattctgc cataacataa gtcacttcta
     1981 agccgatgat aatttgataa tttttttcag ttggtttaat gatcccgctt atccctaatt
     2041 gcttgattcg ctgttcctcg accatggtgg gatccactac ctctacccgt aggcgtgtat
     2101 tacaactata gacatccagg atattggctt ttcctccaaa cgcttgtagc atttttgttg
     2161 ccatatattc ataattttta cttgctaacc ctaactctgt ttcttctaag gttacttcat
     2221 tgccaaactc tgccttagct tcacgtccta atgtctgaat gtttctctta ttgatcaaat
     2281 aataaaaagt aacgtaatac aaggcaaaaa agaaaattcc gattggaaga atcaaaatag
     2341 cattggtagc gattcgaaaa ttgatgagat aatcaacaat acatgctccg aatgtaaaac
     2401 caattcgtat attgaataag taacagacaa tccctgctaa accggcaaaa agtgcatgga
     2461 tcacgtacaa cataggagaa agaaacatga aactaaattc aacaggctca gtgatatttg
     2521 caataaatga agttcctgca ccgcttccca tgattccttt gaccatctct ttattttctt
     2581 tataagctgc tttatagata gctagacata tagctggtat accaaacatc attactacaa
     2641 aaaaaactga taaaaacagt ccagcctgag gatctccgtt gataaagcgt gtcatctctc
     2701 ctctgaaaac ttccttgcta ggagatgtat agcttcctaa atcgtaataa atatacgtat
     2761 tcaacacatg gtgcagtcca aaggggatca gcaaacgatt caaaaacata aatatcccca
     2821 cacctaatgc tcccatatca acgagcagtt ttgcaaaatt atcaatccca atttggatga
     2881 gcggccagat aaagcccaaa aaaacagctg cgattgtttg tagaatcatc accatagtca
     2941 atgggaattt ttcgcccgca aaataagaaa aaactactgg taatttttgt tctttaaagc
     3001 gattatacgt ccatgccgct actaaaccgg aaataattcc accaaaaatc cccatattca
     3061 cttctgggtc cataatttct aagccttttt tcaaggtagc aatcgctaaa aaaccagtaa
     3121 gtgcaggtat tcctttgtcc ttatttttga caaaaccgat tgcaactcct atagcaaata
     3181 agatatccaa gtttccaaaa acggcatttc cagctgcacc aattactggg atgttcagca
     3241 tatcgtcagc tgataaacgc atgatcaatc ccgctaatgg catcgctgca actggaagta
     3301 gcatcgctct tccaagcttc tgcacatttg atttaacatt catttttatt cctcctctat
     3361 taaatatcct catatgttac taactcaatc aaaggatcat ttttcacttt ttgagcaaat
     3421 gctgaatgaa ttaaaaattc gacttggtgg gtacgaggat acacaaaact tgaaccattt
     3481 aacaattcct gatccaaata cgctgcgtga cacatgactt cgatcgtttt atcttctctc
     3541 aatatcatga gtaaacttgc caaatattct tccacactcg tattgatttg tcgttttttt
     3601 tcatcagttt ctcctacgac atcgaaacaa ggctcaaaat aatcgacatg acgaacttca
     3661 tcttttcgtt caaagttgct ccgaaccggc aaatcatatt tttttgctaa tgtaacaact
     3721 acctcctgat tttcatccaa agtatgagta tgatgatgac tgtctaaatg agttggtatg
     3781 atccccgcat gataaatttt ttgaatctga gcattccatt cctgatacag ttgatctttg
     3841 tcaatgttaa atggatgctg ataataagat aaggatctga actctccgct ttcgataaga
     3901 gtatcgacag ttttgaggag tggtttgcca cacgtcaatg ttaaatggac tcctacacct
     3961 agcctaggca tttcctttct tagtttcaca gcatgctcga aacccggcat atttgccatc
     4021 aatgtagttg atgtcaaaat tcctcgctga taagcatcca taatcccata attcacacca
     4081 tggctatagc caaaatcatc cgaattaaaa atcacttttc ccatttcatt ctccttcttt
     4141 tttctactaa aataggcgca accaaataat catagtccat ttactatgtg tcatttggtt
     4201 gcgcctatag atagttacgc ccttatttta atagattctt gctagatgaa ttgccaaata
     4261 gatgatttca ttttcttgaa tggcaagttg aaattgctgt tcgatgatat ctttaatctt
     4321 tagtgctgta caatacgctt tgctatgttt aaatgtttca gtaaaaaaac caatattttc
     4381 tactggcgtt tcttcctgat aaatcaagcg tttaaccagg aatttgatat gaaccattaa
     4441 gcgatgataa gtcagtgatt ctttatcata aacgtttgaa taggattttt ctagatggga
     4501 caaaatcgtg gtcgtcattt ctactatttt taagctcttt aaactattag gctctcctag
     4561 ctcagcatta atgatatgca tagtgatgaa tcctacttca tttgacccta actcggtttg
     4621 atatcgatga ttgattcgct cgaccacttc tactgctata tcatattcat ttggataaag
     4681 gaatctcatt tctggcaaca taattgctgt gacatctcta tcttctcttt ttcgttgaat
     4741 agcaaaataa atatgatctg tcaatgtaat atagatattt gaatctaatg gagaggagat
     4801 cctagctgtt atcagttcaa tcacttcttc cgcaaaatcc ataaattcga ttggaatctg
     4861 cgagactatc tcactgaatc gtttgatctt ttctttagaa tctaatacaa ataatttgtc
     4921 agcatcctca acatcaaatg gcttactcac tttagcagaa aagccaatcc ctttccccat
     4981 cgcaattttt tctattccat cgtcatcgat caatacagca ttatgattca gctttttcat
     5041 cacatacacc gttaattcac ctcctctata tgataaaaca aaacaacttg cagactcctt
     5101 catacatatt tttgtctcca aacaattttt aaagacaaaa aacgacctaa gaaagaaccc
     5161 tttcttaggt cgtgcctaat tgaatagtag caccctacat aatttacaaa aatagtttaa
     5221 cacataataa aagcgttatc aatatctttt ttactcgttt tatgataata cttgtatcga
     5281 attgatttgg aggtaattac ataaaaacaa aaaaaatata gcaactctct ataagaaagt
     5341 tgctatattg ataattatac cggcggccgg ggtcgaaccg gcacgtcctc aacggacact
     5401 ggattttgag tccagcgcgt ctgccaattc cgccacgccg gcaaatttaa aaataataac
     5461 tggggtagct ggattcgaac caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg
     5521 gctatacccc aagaataaag ggcgaatgat gggaatcgaa cccacgaatg ccggagccac
     5581 aatccggtgc gttaaccact tcgccacatt cgccatcata aaagatgtta tttaatttct
     5641 caataaaaaa ctaagatgaa gacatcttag tcaataccgg cggccggggt cgaaccggca
     5701 cgccctcaac gggcactgga ttttgagtcc agcgcgtctg ccaattccgc cacgccggca
     5761 agttgattta ttagtactaa ggcggtaacc ggatttgaac cggtgatgaa ggttttgcag
     5821 acctctgcct taccacttgg ctataccgcc attatactat tatcaatcta taaaataaag
     5881 aataaattat agaaactggg gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc
     5941 cttgccttac cgcttggcta taccccaaga ataaaaaggg cgaatgatgg gaatcgaacc
     6001 cacgaatgcc ggagccacaa tccggtgcgt taaccacttc gccacattcg ccatggcagg
     6061 ggcagcagga attgaaccca cactaacggt tttggagacc gctgttctac ctttaaacta
     6121 tgcccctata aaatggagga gagtggattc gaaccactga accctaagga acggatttac
     6181 agtccgtcgc gtttagccac ttcgctactc ctccatggtg gcgcgggaca gaatcgaact
     6241 gccgacacac ggagcttcaa tccgttgctc taccaactga gctaccgcgc catattttaa
     6301 aattattaat tgaataacaa gaacgacggt tccgacggga atcgaacccg cgatctcctg
     6361 cgtgacaggc aggcatgtta acccctacac cacggaacca gttcattatg gaggttaacg
     6421 ggatcgaacc gctgaccctc tgcttgtaag gcagatgctc tcccagctga gctaaacctc
     6481 caacattcaa ttaaaatgac ccgtacggga ttcgaacccg tgttaccgcc gtgaaagggc
     6541 ggtgtcttaa ccgcttgacc aacgggccag gtaaatttgc tacggagagt aagggattcg
     6601 aacccttgag acagtttggc accatctaca tgatttccaa tcatgctcct tcggcctctc
     6661 ggacaactct ccagagtgaa agaagctcaa tactctttct caaaatgaga actccggcag
     6721 taggactcga acctacgaca tcatgattaa cagtcatgcg
//
LOCUS       DAFLWZ010000107         6625 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000107 DAFLWZ010000000
VERSION     DAFLWZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.110"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            141..2816
                     /locus_tag="L1V38_002652"
     CDS             141..2816
                     /locus_tag="L1V38_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBN1317129.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2998..3237
                     /locus_tag="L1V38_002653"
     CDS             2998..3237
                     /locus_tag="L1V38_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317130.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3253..4626
                     /locus_tag="L1V38_002654"
     CDS             3253..4626
                     /locus_tag="L1V38_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317131.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4630..6264
                     /locus_tag="L1V38_002655"
     CDS             4630..6264
                     /locus_tag="L1V38_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317132.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6427..>6625
                     /locus_tag="L1V38_002656"
     CDS             6427..>6625
                     /locus_tag="L1V38_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317133.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2321 a         1071 c         1330 g         1903 t
ORIGIN      
        1 ttccaaaatc acaacttttt tcttttgtca agattttgag tgggatatat ttttgtagaa
       61 ctgaagatca tgaaattatg agaggttgga ggtaatgtag tcatacaaat aaaaattttt
      121 tagaaagtga gtggtaatta atgaaaatga atcacacttc aattcagaag catttacaac
      181 tgttaaatac actggggatt tcttatgtta atttgagaac tttttctaca ttaaacaaga
      241 aaaccgtttc tcatattttt tctactgcag attctcaagc aattattaac tatttagaaa
      301 aacagaaatt gtctgaaggt acagtaaaca taacttataa tcctattaaa caagaggtga
      361 ttacacaaaa aaagcattct gtgagagaca atgatattga aaaaattcgg tttgtattta
      421 ttgatattga ccctaaaagg aaagagggaa gtgcaacaga tagcgaaaag aaaaaggcag
      481 aaaatgttat ggaacaagta gaacgttatt tgaaagaaaa gagaatagaa tcatttgtaa
      541 aagttgatag tgggaatggc taccatattt ttcttcccat aaatgaacaa ccaaataatc
      601 acgagacgat tcttactatt cagaattttc ttcaattact tcaccgaaga tttggagtag
      661 aagatgaagt tgatattgat acttctgttt ataatccttc aagattatgc aaattagttg
      721 gtacaccagc ggtcaaagga aagtccacaa aagagcgtcc gcatcgttta tctagtttcc
      781 tttctattcc cgataacata gatagaagta attgttttaa aattcttgaa cagatagttg
      841 aagaaaattc catgatgtca acctctagag taaaaagcca tccatctttt agagaagtgt
      901 taccttttat tcaagcagac tataaacaat ggttagctca ctatcctgaa ttaacttata
      961 ccataaaaga gggcgatcat aaaggagtta ccttacttat atttgacgaa tgtccattaa
     1021 gaaaacacac gaataattct aatggttctt gtttgtctgt tacggctgat aataagattc
     1081 gatttcattg tctgcatgct tcggataaaa ataaagatat tcaagacttt gtaaaaaaat
     1141 atccgttgcc aaaacctgta aatccttctg tagaatcatt agaatccaat caagaatatt
     1201 attttgacca gtttaaactg aatcaagaag gagtattttt ggtgaaagaa ggtcaagaag
     1261 aaaaagttgc ttgtccgatg tttattaagc aaatacgcaa aaatatcgaa caaaaagtca
     1321 ttacacttgt tcttgcctat tatgtcgatc attgttggga tgaaatagaa atagaaggtg
     1381 gatgtttaca aactaataat tttaaacaat tagcaaaaca tggcttaatc attaaagcta
     1441 gaagagaagc tgaagtcgtt gactttttac agattcaacg ggagaatgct ccaatctttt
     1501 ttgaacatga atctcttggc tggaaaaaag aaaatgaagc aatgattttt cagttacaag
     1561 attcttttgg acgtgaaatt ccttctgtat taactaaaaa ctcatgctac caattaacaa
     1621 ctaatggtac agaagcggaa tttgacgcat tggttcataa gtatgtttta ggaacgaact
     1681 tagaacttgc ttggtcgatt ggtattgctt ctattgtgtt aggctattta aacgttacga
     1741 aggctaatac ttttttgagt ttactaatta acctacaggg caagagcaca acgggtaaaa
     1801 ccactacgtt acactttatt gcctctttat ttggaaatcc aactacggtt cttagaaata
     1861 tgaatgctac caataaagcc attataaagc tagcatcaaa caatcaggga ggtgttccac
     1921 taatactaga tgagttagga gcagcaactc aaaataactt tagctcgttg atctatcaat
     1981 tagcttcagg agaagaaagg ctaagattag attctaattg tcagcttatg ccacaagaga
     2041 ctttttctgt tttgaccctt acctcttctg aagagcgttt ggaaaattat ttcaatgaga
     2101 aattaactgg tttgaaagtt cgatatatcg aattttctga tatcaagttt acaaaggatg
     2161 cgaatcacgc agagaaagtt aaaagtcttt cttctaatac ttttggttgg ggtataaagt
     2221 tatttctttt gaaactcttt gaacaaggga ttacaaaaat tgaagcaact tttgtcgaag
     2281 ctcaaaaaaa actatgggct gttttacctg aacattcttt gaagcaacgc attggtaata
     2341 atctagcttt gatttatagt ggagccctcc taattcaaga tatactgggc tatcctttac
     2401 gattagagca tatacagacg gtgcttatta attcgtacga acagttaatt gtagatacta
     2461 gtttaggaag tgagcaaacg gtatttgacc gagtgaaaac attgttggtg atgaatagcc
     2521 ataaattttt aacaaacagt gacaacaaac atacgcccag tacgatttgg ggaaaagtat
     2581 caattcaaaa aaatggggat attaaggtaa atatttttcc tatcccgttt gaggacttgt
     2641 taaggcgaga atttcaagta aaggatctaa cctatctttt taggcaattg cttgattcgg
     2701 gtaatatgtg tgcagaaaaa gggagaagaa cgaaacgtat tcacatgaat cgtcaagttc
     2761 ttccaacata cgagattcta ttaccttctt cactcaaatc gtattttcga ttgtaattta
     2821 gaataaacca aagtatgaaa gtgaggcacc atgttatgga aatatttctt attgatttag
     2881 caaaacaact gattacttat ctgtatgata gcgagcaaac ccaaacggaa gtaaatgaag
     2941 cttgatctat gcttcattta cttcattcaa tcaaacatga aagaaaggaa aattctaatg
     3001 actaaaaata aaatgacact aaaagcagag gttcttctgt atattcaaga acatttttca
     3061 aatcaagcct tttttacaaa accaatttac ttggatttcg aaataagagg ggtatctgct
     3121 ggatctatcg ggggtactct tcaagcgttg aagaacgaag gatatttaga aaatcacttt
     3181 gtgcaacgtt cgttcaatag aagagtcgtg aaaaaatggt atttagttca ttcatagaga
     3241 ggggaatcaa gcatgcgtgt ggcttgttat gatcgaacgt ctgtttatga agaagcgaaa
     3301 attagtaatg acgctcaata tgatgcagtg aaagagtatg ttttagagaa atatgaacaa
     3361 attccccaac gattttcaga caaaggagaa tcaggggaaa aagcggagcg tccagctttt
     3421 cgacagctta gagcttgggt ttgtgcgtca gaagaagagg gggtgatcta tgtttggcgt
     3481 tatgatcgat tggcacgtca agccaaaata gccttagaat ttattgagtt gtgccaacaa
     3541 catcaggttc aagtgtattc gatttctgaa cctcttcctg cttctttctc acacgcgtca
     3601 acgaataaac tatttgtgca attattgttc acttttgcag aacaacaacg aaacgtcatt
     3661 attgagaatg ttcgtgccgg actttcctat aaaaagcaac aacggcaata tttgtcttct
     3721 gcggtaccat atgggtatcg tttagtgaat gggaaaatcc aacaagaagt acacgaagca
     3781 aggattgttc gctatatttt tcaactttat ttgaccaaaa aatatggcta caaaaagctt
     3841 tgtcaacgat tgacgcaaca aaagcttttc ttccgcgaac gtccttttca gccctatcat
     3901 atttatagta tcctaaaaaa tccattgtac tatggcgaaa tcaaaggagg atctttgggg
     3961 aagtatctag gaacctttga accgattctc tcgaaagcaa cctttttaca agcccaagag
     4021 attcgccaat caaggtgtac agctaaaaaa gatacgtatc tgtacttatt acgtcaaaaa
     4081 attcggtgtc ccttctgtgg tcgtcatctg agttcgaagt atcaatggaa tacaaagaag
     4141 acgaagacgc ttcattatta tcattgtacc gaccgaagct gccaaggaat ttttcttcgg
     4201 gcagaaaggg ttgagtcaga agtattggaa aagatacagg ctttttttca atacgaaggc
     4261 gtctatcaag ccttgattgc ccaattaacg caacaattag ccgaaaagcg aaaagatgaa
     4321 aaacgcaaag taatccaaca aaagaaacaa gaagcacaat ggattaaggc atttgaagag
     4381 ggcaattgtt cactggaaga actcaagcaa caactgcaag ctcttcaaaa gccgatgtct
     4441 acttcttcgt ttctttcact ccaacagtgt gaagcaaaag tgaaagaatg gcttcaacta
     4501 aaagacctct ctagtcgaca attattatgt gactatgttt gtcggattga ggtaacaaag
     4561 gataaaacag tttgtgggat ttacttccga caactgacac aaaatatttt agaaaggaac
     4621 gaatgatcta tggaaatgat acaaaccaaa cgagtcgcat tgtatattcg cgtgagtaca
     4681 caagaacaag ctttagaagg acatagtatt caagcacaag aacaaaatgg acgacagttt
     4741 gccgaacgga tgggctatga agtggtagaa gtttatgccg atgaaggaat cagtgggaaa
     4801 tccacaaaaa atcggttcgc ctatcaacga atgatgaacg atgctcggaa ccatcgtttt
     4861 gatctactag tgatttggaa attgacccgt ctcggacgca atatgttaga tgtcttacaa
     4921 acagtcgagg aattattgcg atatgacgta ggattacatt cgatctcgga acaatttgac
     4981 gtgaccactt cgacaggtaa attgatgtta caactccttg ggagtttcgg tgaatttgaa
     5041 cgcaaccaaa ttgcggagaa tgttcaaatg tcaatgcaaa gcttagtgaa agataaaaag
     5101 cgttatgcag gaggccgacg tttaggctat gtcagtggta ttgacacgaa tggtcaaaaa
     5161 caattggtca ttgaaccaga agaggcgaaa attgttcgtc tgatctatgc aaaatattta
     5221 ggcggagcag ggtatcgagc gattgccaat tttttgaatc gtcaaggata tcaaacagtc
     5281 aaaaagaatg ctttttctac cacggcagtc aaagatatct tacgcaataa aatttatgca
     5341 gggtatttag aatatgcgcg ctacatcaat tgggaaacca aacgacggaa ggggaagaat
     5401 ccgagaccga ttttagtgaa aggaacccat gaaccgatta tttcggaaga agattatcaa
     5461 aaagtacaag aacgccttgc tttagaagga aaacaaccca aatggaacca tacaggtgaa
     5521 aatgtattga caggcttgtt acgttgtcca gaatgtggcg caccgatggc agcgagtaat
     5581 gtcacaaata ccctaaagga tggcacaaag aaacggattc gatattattc ttgttcagtc
     5641 tttcggaata aaggagcaag tgtgtgtcat gccaattcga ttcgtgccga acaagcggaa
     5701 acatttgtcg ccgaccgatt aaaggagatc gttcagctac cagaagttct tccccgattg
     5761 gtggcagcgt taaatgaaga aatagtgcga caaagccaac cattggaaca agaactcgtg
     5821 gtgttactgg aacgaaagga agaattgaag actaaaattg aaaaatggga agctgctttg
     5881 gaagatagtc ctgaattgtt tccgatgtta aaagaccgct tagacgaatt gactgaaaaa
     5941 cgacgacagt tgcacattcg agaaaatgaa atcttaggga tctttcaaca aggagagccg
     6001 attcaagtca aagatgtcca acggatattg actagtttgg atcgttttct tgcccagagt
     6061 gagaagaagc aaatcaaagc cttgtatcgt acctttatag agaaaataac ctttgatcct
     6121 aaccataagg agatgttgga aattacgatg aaattcacgc atgccgtggt acaacaattg
     6181 aatgagcaat atcaaatagc cgtatccaaa acaaaggata cggctatttt tgtgttaaaa
     6241 acacccttta cgttaacgat ctagtctagg ttatatcaaa caacgttaga ggggcgctaa
     6301 cgcttctcta gcgatttgaa atcgttagag aagtagttag ggaggtcctt atcataaata
     6361 gggatattta ttaatgaata tttgaaatat aattgtatat aagaattaaa aagagtgggg
     6421 atagatatga aaaagatggg taagtgtatt ttatgtgaaa aatacactga acttactaaa
     6481 gaacatgtac cacctaaaaa atcagggaat actggaggta aaaagaccag aactggtaat
     6541 ttagatgatt tccttaagag cgattttaca aaaggtgatt ttccgaaggg gattaaaagg
     6601 aaacctcaag gaaatgttta ttata
//
LOCUS       DAFLWZ010000108         6543 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000108 DAFLWZ010000000
VERSION     DAFLWZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.111"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(1237..1902)
                     /locus_tag="L1V38_002657"
     CDS             complement(1237..1902)
                     /locus_tag="L1V38_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1317134.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2082..4064
                     /locus_tag="L1V38_002658"
     CDS             2082..4064
                     /locus_tag="L1V38_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBN1317135.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4068..4706
                     /locus_tag="L1V38_002659"
     CDS             4068..4706
                     /locus_tag="L1V38_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1317136.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4734..5162
                     /locus_tag="L1V38_002660"
     CDS             4734..5162
                     /locus_tag="L1V38_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317137.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5619..6530
                     /locus_tag="L1V38_002661"
     CDS             5619..6530
                     /locus_tag="L1V38_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1317138.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2247 a          991 c         1211 g         2094 t
ORIGIN      
        1 actacctgta ttagtcctct tttttgacca gattttgacc agtctatttt acattctaat
       61 atattcatat gagctaattt tatgattaaa tggtaagtgt ttccttgttt gttttagttt
      121 aaactagtgt gtaatttaaa aatctatatg gaagggtctg tggggtaata cttaaataaa
      181 ggctaggaac ctgataacat caaggttcct agccttttta taataaaatg aagcgaaaat
      241 aatttctttt aaagagccga gattatcagc tatataagag tgaatttgat gcaaaaaaca
      301 gagccgaaac agtcttggtg ttcgtagctc tgcttatatg tttcgaattt aagacaaaga
      361 gttggcaaaa gatgttgata aggaagataa gataactgtg ttatataaac taggtaacta
      421 actgtaacaa gctaatttta agagattctt attagaagac gtttaggaat ataactaaga
      481 aaatgattat acaggtaatt gtcatttcaa taatgttttc taattttcgc gtctttgttt
      541 taagaaaaag gccagaatca gttggaaaaa agttcgtacg atagtgaaga ggggcaaaat
      601 ttcctactaa tattcccact aacaagagat aaaacggcca ggttggtgtg attcctctat
      661 aaaaaaatgc ccatgctacc gaaatcccat agattaacaa ctgaacaatt tttacaatga
      721 aaaaattgtt ctgccattac tcaaagtctc ttcctccttg tatcgtttat ttgtttcatt
      781 ttatcattat gataggcgct tgaacaatcc attttgtatt ttattgagta ctcttggata
      841 aactaccagc gattatcata tttatttatg ttactgtaag ccatcatata aaagtaaatg
      901 agcagatcat agaaatataa aaaagaacta aaattgatct aaattatgtg cagcttgact
      961 acgtaccaat ctatattact tactagattg gtcgttaatc tattcggatc gaatgagcaa
     1021 aatatttttg tgaatgtcca tccttgatta tgattccaaa aagaatcatt gggaggctgt
     1081 ggcgtaaata ttatactata agccagaaat acctatcatt ctgaactttt ttatttagga
     1141 actttcatct caaggctttt tcaattaatt tgtacccctg ttttttggat aagatcatgt
     1201 gcattgattt tttctatctc tacgttcatc tcctacttaa tgcctatctg gctcctgagg
     1261 gcttcttttt aaggcgtcgt catagtcttg gctgaggatt tcttggtaat ctgagggaat
     1321 ggcttcccaa gtgagcaggc gaacgttcat gacgtgtttt cctttgtgtt tgattacagc
     1381 atggtttttc tctttttcta cctctccagc gtgaaaagac agccatgtac catggccaaa
     1441 gatatcatta catacccaac gttcgatgga attgtccacg tatcctacag ggagtgtggt
     1501 atagccgatt tgtggtttca aaaaaggatt gaatcgatcg atcgtttcat ttttgtattg
     1561 ataattgata agaaaaagat agaccaaaca aaagacgagc agaaagaaag atagtgtctt
     1621 tttgagtgag aagggttgtt ttgatgaata agatttcttg ttaacaagag gttcatctgg
     1681 caatgttggt tctattgatt cggtagctga ttcaatagaa ggaaaatcaa tcggcagacc
     1741 taaagtatga tgtaaaagtg acagcatttc aaggtctggc attgtacgag aattttccca
     1801 actagaaatc gttttatcgg aaacaccaat tttttcgcct aattcttttt gcgtaagctt
     1861 acaatttctg cggtaagttc gtattttttc tccggtgttc atcttcttct cctttcgatt
     1921 ctacagtata tagatttatt ctacatgacc tatacacttg atagatacgt ttttttgatg
     1981 aaaaacggta tgattttatc aaagaatcat ttaagtaagg gagagtggtg ataatcaaaa
     2041 aaaagttcac agttttactc acaatcatag tgaccggtat catgagtggt tttgccttgg
     2101 ttagtataaa taaacaggta ctctatcgga caaatgaatt tttccatcaa acagatactt
     2161 atactccgat tcgattgcca caacatttta ttgggcaaga agaatatgag cagctaatca
     2221 tggtatttga aaatgtctca tcagaaactg agctttctta tatgaaaaaa acagtaaatg
     2281 aatccaatga agtagataca tcttggaact tcaagataca gccaaagctt gaaatgacat
     2341 tgtattatca aggggatgtc aaatcttctc acgagaaggt accctattct aatacctcct
     2401 ttcgcgtaac gtccattgaa gaatcgatca aaataaaaga ttttgaaggt gaatttttct
     2461 tgatgacgag agaaaaagaa gcctatgaac ggttcatttc actattcact gatcgattca
     2521 atcaagcatt tcacactgat tatgccacta atatttttga agactttgaa aatagctatt
     2581 cgtattcggt tatttcaaat acagacgtat ataattatcg agtgtattta actattggat
     2641 tgattctttt attccttttg ttatcatcct ttttcttatt gatgaataaa gaaatcagtt
     2701 tattgttgaa taatgacttt tcattacatc aagtattgtg gtgtttattg gggaaaaaga
     2761 aaatcattat tacattcata attgcaggaa tcattggtgg ttttattttt atgtattata
     2821 aggagcaatt tctttatttg ttccagatgt acgttttctt gttcagcgga atatatggta
     2881 tctctttgat ttctctttta ttagttgaaa aaatcgcttc gttaagagaa gcgttcaact
     2941 atatccaata cattcttttt acatttggat tgttgttttc tcttcttttg accgttgcca
     3001 atgtcgaatt agcaactatc gttttttctt cttcacagtt agctgtttcc catgaaccac
     3061 caaaagaaat cgctggtgag gactatcatg tattttatcc agtaaccatc gggaaaaacc
     3121 acgtggattt tatttattcc aatcgttttg catcagcagc agatcaggaa ttatatgaaa
     3181 ctttgaataa aaacggaagt atattagtca atgtatcaga ttacttgaat gaagaaaatg
     3241 aacagtttgg cagagggata aaaataaatc tgaattatct taagaaattt cctttgattg
     3301 atgtctctgg aaggttgatc caaataaccg aaaaagaaac gcaccctgtt atattgatcc
     3361 ctgaacgata tagacataca gatttaaaaa atgacctggc gcaaataaca gaatattatc
     3421 aagaaatcag tgaaaaagaa ccgaaatttc tatttataaa aaacaatcaa cccatttata
     3481 catttattcc ttctatcccc tggatcgaac attatccggt tgttgaaata ctgacattga
     3541 aaaacagtat gtatttggaa agaaatattc tcagcggaga aatctatcca ccgttaaaga
     3601 tcaagatagg ctctttgtcg aaagaaaggt tatttgagct gattgaagaa agtcagttac
     3661 gtgataactt gcagttatca tttccgtata ctcagactga agagatagct gtcaaagtgt
     3721 taagcagatc atttcattac ttgatacaga tatttttact cactttcttt tctttcttct
     3781 tgttgagcta tgtcatgtta tgcatatatt ttgtctacaa ttgtcggaaa atcgctatct
     3841 ttcgttcaag tggttattcg ctctttgaaa cgtataaaga tttcttcatg atgaacctca
     3901 tcaaatgggg aacgacaagt gtaatcttcc tttttcttat agaaagagag cctaaatatc
     3961 tttttaatat ttttttcttt agcttcattg attttattct ttcagttgtt tttattttgt
     4021 ctacagaaaa gaaaagtcag ttattgctga tgaatggagg ttaacaattg gagccgttga
     4081 tagtgataaa aggtgcgaaa aaaatcattc gaaacaaaac gattcttcat ttggatcgtt
     4141 tcactgcgga tgctggggat cttgtgactg ttgttggaga aagtggagca ggtaaaagta
     4201 cgttattgaa tatattagga ttgaatgatc agttcagttc aggacaattc tatttgttcg
     4261 atcaagagac gaaacaatta actgggagag agaagcgctt gataaaaaga aataccatat
     4321 cttttctttt tcaagatttt gggttgattg aatatgaaac aatcgatttt aatttagata
     4381 ttggattgaa gttttcgaat ttaaatgttt cagataagcg aacagcaaag tatgaggcat
     4441 tgaaaaaagt aaatataaac aagaagctaa gtacgcctat ctacacatta tctggtggtg
     4501 agaagcaaag aatcgcctgt gcgagagtct tattgaagaa tagcaaaatc attttagccg
     4561 atgaaccgac tgggtcattg gataaaagaa ataaggataa agtagttgaa atcttatcgc
     4621 aacaagcttc ccaaggtacg ttagttatcg tagtcacgca tgatccatat ctgaccaaaa
     4681 taggaaacaa gaagatcatg ctttaaaaat caaaaaggaa aggatgtcgt tttatgaaaa
     4741 aagcagttat tatttgtgca ctagggatag gttttgttgg aggaaacgct atgtcatctg
     4801 aagtggaagc aaattcagtt cacggtgaaa tctattacaa atctttaaag ccaggagaga
     4861 ttcattttga tgctaaaggt aatattatta agtcaaattt accagtagac cgggaaattt
     4921 ctagaacagc aattaatcat agctctggaa gatgggttta ttatagtgat acaacttgta
     4981 cgagaaaaac aggtcattct aaccactata gtcgtgtcta taatcgtcac ggtgcaaaag
     5041 cgaaagttgg aaactctatt cgatcagcaa atgcaacaaa aggagtatgg gcctatgcaa
     5101 gtgcgacagg aaatagaact gacacattct catgttggta caatccaacc ggttggtatt
     5161 aagtatccaa aagtttatat aaaatagaaa aaacatataa tgaaacagcg ttaaaagtta
     5221 tttttggtag ttttaatata ttcattttta gttgtataaa aatatatcat aataaaaaca
     5281 acaaaaaaat gtctggaaaa tcgaacataa aagtgtctga tttgaatatc ccagcagcgg
     5341 aagaagaaaa acaaaatcga taacatttgt tctaagaatt agttacgtta aatacggaac
     5401 gcaagataga cttgaaaaac ggtaacaaaa gaagtagtat attaaggtgt gatgtgctac
     5461 ttgacattta ttctgctgag cgaactttct ggattgtgta gccttatatc tattcaggac
     5521 gtatcgagca gattagtaaa ggtgttcttg atgattttca tcttgaacac ctttgttttt
     5581 agcaattcgc aaaaaacgaa aagtaggaga attgataaat gaaaaaaaga tttttagcac
     5641 ttgccatcgt actaggcact ggcttattgt caggctgtac gaatgccggt gaaaaaacag
     5701 ccgttagtta taaaggcggt acaatcagcg aacaagaagt aatggatagc ttgaaaaaaa
     5761 tgcaaggagc agattccgct gtgcaacagt tgatcgttta tcaagtattt gaagataaat
     5821 atggagatga cgtatcaacc aaagaaatcg attctcaata tgatcaaaca aagaaacaat
     5881 tgggtgattc atttgattca caattgaaat ctgcaggtta cacagaacaa acattcaaag
     5941 acagtatcaa acaaagtcta gcctttcaag aaggtctaaa gaaacatatc aaattgaccg
     6001 atgaagattt aaaaacggct tgggaatctt tccatccaga agtggaagct caaattatcc
     6061 aagtagcaag tgaagatgat gcaaaagatg tgaagaaagc tgctgataag ggagacgatt
     6121 tctctaaatt agccaaagac aagtcaactg atactacgac aaaagaagat ggcggaaaag
     6181 tgaaatttga ttccactact acaacggttc cggcagaagt caaagaagca gcctttaagt
     6241 tgaaagatgg tcaagtttct gatgtgatca cttctaccaa tgcttcaact tatactacgg
     6301 aatattatgt ggttaaaatg gtgaaaaacc aaaacaaagg caacgacatg gataaataca
     6361 aaaaagaatt gaaagaaatt gcaacagaca caaaattaag tgacagtacc ttccagaata
     6421 aagtaattgg cgaagtattg aaagacgcta atgtaaaaat caaagacaaa gactttgaaa
     6481 atgttttgag tacattcact tcagattcta gtacagcaag tagtaaataa gcggtataaa
     6541 taa
//
LOCUS       DAFLWZ010000109         6403 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000109 DAFLWZ010000000
VERSION     DAFLWZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.112"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            127..579
                     /locus_tag="L1V38_002662"
     CDS             127..579
                     /locus_tag="L1V38_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317139.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="L1V38_002663"
     CDS             593..1282
                     /locus_tag="L1V38_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317140.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPILPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="L1V38_002664"
     CDS             1407..3758
                     /locus_tag="L1V38_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBN1317141.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="L1V38_002665"
     CDS             3838..4233
                     /locus_tag="L1V38_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317142.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="L1V38_002666"
     CDS             4558..5175
                     /locus_tag="L1V38_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317143.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="L1V38_002667"
     CDS             5216..5515
                     /locus_tag="L1V38_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBN1317144.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="L1V38_002668"
     CDS             5549..5716
                     /locus_tag="L1V38_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1317145.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6366)
                     /locus_tag="L1V38_002669"
     CDS             complement(5761..6366)
                     /locus_tag="L1V38_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317146.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2197 a          892 c         1262 g         2052 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattttgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttccat
     6301 cattgccaat tgtcgatcca aattttgatc ttgtgaagat actcgaatat agccaatttt
     6361 tcccataaaa aactcctttt taaaagtgat ataatttaca tgt
//
LOCUS       DAFLWZ010000110         6387 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000110 DAFLWZ010000000
VERSION     DAFLWZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.113"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            330..1175
                     /locus_tag="L1V38_002670"
     CDS             330..1175
                     /locus_tag="L1V38_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1317147.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="L1V38_002671"
     CDS             1456..2676
                     /locus_tag="L1V38_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBN1317148.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="L1V38_002672"
     CDS             2673..5393
                     /locus_tag="L1V38_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1317149.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="L1V38_002673"
     CDS             5377..6321
                     /locus_tag="L1V38_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1317150.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DAFLWZ010000111         6334 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000111 DAFLWZ010000000
VERSION     DAFLWZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.114"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(99..1229)
                     /locus_tag="L1V38_002674"
     CDS             complement(99..1229)
                     /locus_tag="L1V38_002674"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBN1317151.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="L1V38_002675"
     CDS             complement(1878..3080)
                     /locus_tag="L1V38_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317152.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="L1V38_002676"
     CDS             complement(3140..3343)
                     /locus_tag="L1V38_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBN1317153.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="L1V38_002677"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="L1V38_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="L1V38_002678"
     CDS             4880..5692
                     /locus_tag="L1V38_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1317154.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1889 a         1300 c          998 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaa
//
LOCUS       DAFLWZ010000112         6287 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000112 DAFLWZ010000000
VERSION     DAFLWZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.115"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..177
                     /locus_tag="L1V38_002679"
     CDS             <1..177
                     /locus_tag="L1V38_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317155.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="L1V38_002680"
     CDS             190..690
                     /locus_tag="L1V38_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1317156.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="L1V38_002681"
                     /pseudo
     CDS             787..2634
                     /locus_tag="L1V38_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
     gene            2637..3533
                     /locus_tag="L1V38_002682"
     CDS             2637..3533
                     /locus_tag="L1V38_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1317157.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="L1V38_002683"
     CDS             3583..3972
                     /locus_tag="L1V38_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1317158.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6287
                     /locus_tag="L1V38_002684"
     CDS             3959..>6287
                     /locus_tag="L1V38_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1317159.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2119 a          933 c         1347 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tagtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacg
//
LOCUS       DAFLWZ010000113         6173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000113 DAFLWZ010000000
VERSION     DAFLWZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.117"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            725..811
                     /locus_tag="L1V38_002685"
     CDS             725..811
                     /locus_tag="L1V38_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1317160.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="L1V38_002686"
     CDS             complement(932..1621)
                     /locus_tag="L1V38_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317161.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="L1V38_002687"
     CDS             complement(1866..2780)
                     /locus_tag="L1V38_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1317162.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="L1V38_002688"
     CDS             complement(2762..3142)
                     /locus_tag="L1V38_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBN1317163.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="L1V38_002689"
     CDS             complement(3592..3879)
                     /locus_tag="L1V38_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1317164.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="L1V38_002690"
     CDS             complement(3899..4123)
                     /locus_tag="L1V38_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBN1317165.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="L1V38_002691"
     CDS             complement(4578..4748)
                     /locus_tag="L1V38_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317166.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="L1V38_002692"
     CDS             complement(4763..5296)
                     /locus_tag="L1V38_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1317167.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="L1V38_002693"
     CDS             complement(5317..6159)
                     /locus_tag="L1V38_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1317168.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFLWZ010000114         6029 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000114 DAFLWZ010000000
VERSION     DAFLWZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.118"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(68..370)
                     /locus_tag="L1V38_002694"
     CDS             complement(68..370)
                     /locus_tag="L1V38_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317169.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="L1V38_002695"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="L1V38_002695"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="L1V38_002696"
     CDS             complement(1127..1900)
                     /locus_tag="L1V38_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1317170.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="L1V38_002697"
     CDS             2044..2394
                     /locus_tag="L1V38_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBN1317171.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="L1V38_002698"
     CDS             2375..3091
                     /locus_tag="L1V38_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1317172.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="L1V38_002699"
     CDS             3091..4539
                     /locus_tag="L1V38_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1317173.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="L1V38_002700"
     CDS             complement(4610..5119)
                     /locus_tag="L1V38_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317174.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="L1V38_002701"
     CDS             complement(5109..5834)
                     /locus_tag="L1V38_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317175.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DAFLWZ010000115         5877 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000115 DAFLWZ010000000
VERSION     DAFLWZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.119"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            641..1375
                     /locus_tag="L1V38_002702"
     CDS             641..1375
                     /locus_tag="L1V38_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1317176.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSKRELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="L1V38_002703"
     CDS             1391..2560
                     /locus_tag="L1V38_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1317177.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="L1V38_002704"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="L1V38_002704"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1317178.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="L1V38_002705"
     CDS             3650..4576
                     /locus_tag="L1V38_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBN1317179.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="L1V38_002706"
     CDS             4595..5845
                     /locus_tag="L1V38_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1317180.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1969 a          955 c         1202 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat caaaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DAFLWZ010000116         5862 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000116 DAFLWZ010000000
VERSION     DAFLWZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.120"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            446..1018
                     /locus_tag="L1V38_002707"
     CDS             446..1018
                     /locus_tag="L1V38_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBN1317181.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            1163..1867
                     /locus_tag="L1V38_002708"
     CDS             1163..1867
                     /locus_tag="L1V38_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1317182.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            2095..2433
                     /locus_tag="L1V38_002709"
     CDS             2095..2433
                     /locus_tag="L1V38_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317183.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2418..3272
                     /locus_tag="L1V38_002710"
                     /pseudo
     CDS             2418..3272
                     /locus_tag="L1V38_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
     gene            3419..3652
                     /locus_tag="L1V38_002711"
     CDS             3419..3652
                     /locus_tag="L1V38_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBN1317184.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3850..5754
                     /locus_tag="L1V38_002712"
     CDS             3850..5754
                     /locus_tag="L1V38_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1317185.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
BASE COUNT         1877 a          982 c         1328 g         1675 t
ORIGIN      
        1 aaaaaaattc ttttcaattt ttatttatgg tgtgacataa ataaagtaaa gttattcttc
       61 taggttaatc ttattaatgc tctttctcac tagtgttgca tgcaacacta gtgagaaaga
      121 gtattaaata tactgcaagg taagacattt ggtaattgaa gaataacaag caaaaaaata
      181 gcagtcaggt ctcttgacaa agtatagttg ctattctttt tttaggccct actttaatga
      241 aatttttgtt tggaggggac gacttcattc ctttgattat ttcagttgaa tttaatagag
      301 aagcctggcg tctattaaga aatacttttc ttgatgagcg tcaatttttt taacggaaat
      361 ctatcctata ctaaattcag taaagaaaaa ggaggaatca aagaaagcta ttttaaacaa
      421 accaaaatta taggaggaat aaatcatgac tgaaaataaa gctactcaag aaagaacacc
      481 ccaagaaaga ttgcaagaag aacaagaaca caaggaacat gttcatcata cgaaaattaa
      541 tgcagcggcc attgcggatc atcttttagg caacatgcat acattacatg tgaaactgca
      601 ccaatatcac tggtatgtaa aaggagccaa tttctttacg ttgcatgaaa aatttgaaga
      661 gttgtataac gaaaatgaaa aatggttcga caaacttgcg gagcgtctaa ttacttctgg
      721 gcataaacct gcttcgacaa cggttgaatt tgaaaaatat tcgatgcttt cggaagatgc
      781 agttaataaa tacgctaaag cagaagacat ggttgaaaat attatcgagg acttcagaag
      841 cactcgtgac ctaactattc gcgcgattcg tttagctcaa gacgagggtg acgatgcttt
      901 agaagataca ttgattgctt ttaaaaatga cttagacaag aacatttgga tgctgcaagc
      961 gttcattggt aaagaagcat tagaagatga tgacgctctt gatgaggatg aagattaagg
     1021 taaaagtaga agctgattta gggattggaa ttctttccag tcctttttcc attttcttga
     1081 tgtgcatcaa tttttttgta gtaagagact tatataataa aagcagcgaa tataaacaaa
     1141 ataaataaag ggggagaatg aattgactaa acatacccat catgaaattg gcgaccacgc
     1201 agcctgtatc cgcttggttc caatattcaa tcacttagag gatagcgcga tgaattacat
     1261 tgctgaaaaa gcccacacga aacagtatca aaaaggagag tttctgtttc gttcacaaga
     1321 aaaagaggat actttatata ttatcaatcg tgggaaaatc cgtatttatc gattggcaga
     1381 ctctggcaaa gagcagctag tgcggatctt gaaccctggt gatttcaccg gagaatggac
     1441 cttgttcaac ccggatgcag tacacgagga atatgccgaa gcaacccgag ataccgttgt
     1501 ctgtatgatt cagcaaaaag atgtccaaga ttttctggaa caatacccag ctatttcttt
     1561 aaaactattg gcggaaatgt ctaaacggtt agaaagttca gaacgtcaaa cgacacaagt
     1621 agccgtggag agtgtcatta cccgtttagt tttgtttttg gcagaaaatg tggaacctga
     1681 aatgggcaac tctcccacca tcaccctgcc gatggcaaaa aaggacattg cttcctattt
     1741 aggaacgaca cctgagacca tcagtcgcaa atttggagaa ttggaggacg aaggattgat
     1801 tcaacagctg tctgggaaaa ggatcaagat tcaggattta gatgatttat tgctttacag
     1861 cgaataatcg gacacacttt tttctacacg ttggtgttct gtcgctcttc attaacaacg
     1921 ggacagaact cagtgctttt gcttccatct gtccgttttt ggctttttta agacagaact
     1981 accttcattc attggaaaaa taaaagcaca aacatgataa ccctcaagtt tttttgtttt
     2041 atttttcttt aagatagggt tgtcgaacaa aacgtaaaaa taagtagggt gaatgtgcat
     2101 tgtttttggg tgatagttgc catcacgttg tcagcagcgg gggcattctt tgtcgtccct
     2161 ttcaccaaga acacgattgg cggcgaagca aaaacgtcta acgttgttga ggcagatagg
     2221 ttagctatgg aaaaagaaga ggaagttgta aaaggagccg gcgtaatcgg acacggaaaa
     2281 gtggcgtatt acgaagcgag tgaccaggga gataaaagtg tattcactgt ttggtttcca
     2341 tggagcttag ccggaatctt gttcagcatc accatgacta gaatgacgcg aaaaattgaa
     2401 gaaatggagc aaatagaatg ggattcgtat taggcgtttt gaatccccat gtggtggaga
     2461 ttggttctgt tgtgattcat tagtatggag tcattattgc agcgggcata ttagcggctc
     2521 tcgagttgag caccaaggaa gcaaaaaaaa aaggactgga agaggatacc attatcgata
     2581 tggccttatg ggcaattccg attggactcc tcggcgctcg gctttattat gtgttatttg
     2641 aacttggtta ttatctgcaa aattcaggac aaatccttgc gatttggaat ggcggcattg
     2701 cgatttatgg gggattgatt gcaggaggga ggacgctata ttggtatgca aagaaaaaag
     2761 gtacttcttt ggcactcgtt cttgatattt tagcgcccaa tgtattgtta gcccagtcca
     2821 ttggtcgttg gggcaatttt atgaatcagg aagctcatgg tggaccggtt actcgtcaat
     2881 tcttggaaaa tctttattta cctgaattta tcattgaaca aatgaatatc aatggtacct
     2941 actaccatcc gactttttta tacgagtcat tgtggagttt gttgggcttt gtcctcatcg
     3001 tcactatacg gaaccgaaaa cagcttttgc gtcaaggaga agtcgctttg agttacgttt
     3061 tgtggtactc agtgggtcgg ttcttcattg aaggtatgcg aacggacagt ttatggattg
     3121 gcgagtggat ccgcgtttcg caagccttgt ctctggccct gtttattggc gcgattgtag
     3181 tatggtttat acgcagacaa gattatccac caatttctta ttattctgat ggcaataagg
     3241 agcagaaaaa gactattaag atggtgaatt gagcaaaaag ataaaaagaa gtgcaaaact
     3301 tgatatgcgt caattttcgt ttgctaaaag tgagctatac tacagttgta aagaggaaaa
     3361 ggcagtgttc attaatctgc tgccgataaa ataaaaacac ataaaggaga taggaattat
     3421 ggaaaaagct atattgcaat tagaaacgtt gtcttgtcca agttgtatgc aaaaaattga
     3481 aggtgccgtg aaatcagtta acggtattga taaagacagc attaaagtat tattcaactc
     3541 cagcaaagtc aaaaccaatt ttgattcagc tgtcacttcg attgaagaga ttcaaaaagc
     3601 tatcgaaaac gtaggctatc cggttcttaa agcaaaagtc aaggccgttt aacagattaa
     3661 atgaactagg caattctgga agaaaagcta tttttccagg attgcttttt ttgttgcaat
     3721 ccgattcgag gtgcttagaa acgataaaag agaactttct aaacttgatg tcagtcaatt
     3781 aattacttag gcaattatct tatactgtgt ttatcaataa aagagaaatt aaatttggag
     3841 ggaaaaagca tgcaacaata tatattaagc aagaaaaatg ttatcaccgt catcagtgga
     3901 ttgttaatcg tactcggttt cttcagtcac tttgttttag aaaacgtagg actttcagag
     3961 tggtctttga tcatcgcctc tgtctttggg attacgccaa ttgccattca agcgtttcaa
     4021 gcaatgaaag tcaaagtcat cagtattgat gtcttagtca gtattgcagc gattggtgcg
     4081 ctttttattc aaaattatga agaatcggct attgtcacgt tcttattctt attcggacac
     4141 tacttggaac aacgaacatt gaaccaaacg cgatctgcta tcaaagaatt gactgaaatg
     4201 gcacccgaaa gcgccttgaa acaaatggat aatggcgaat ttgaagaagt agaagtggat
     4261 gatatagatg aaggggatat cttgctcgtt aaaacgggtg cgaaagttcc agtagatggc
     4321 atagtcctta cgggtgaagg gcatatcaat gaagctagca ttacaggtga agctattccg
     4381 gtcaacaagc tagctgatgc agaagttttt gcaggaacca ttttagaaaa cggaacgatt
     4441 caaatcagag ctgaccgagt tggtgaggac accacatttg gaaaaattat tgaactcgtg
     4501 gaagaagcac aagattctaa atccgaagcg gaacggttca ttgatcgctt ttctaaatac
     4561 tacacaccag ctgtcttggt tctggcaatt gttgtatggg cgttcagtca aaatattgag
     4621 ttagcaatca ccatcttggt tctaggttgc ccaggcgcat tagttatcgg agtgcctgtc
     4681 tcaaacgttg ccggtattgg gaatggtgct cgtaacggtg ttcttttaaa agggagtgaa
     4741 gtcattcaag acttcagtaa tgtggataca attgtatttg ataagacagg tactttaact
     4801 gtcggaaacc caaccgttgc agcgactgaa ctgtatgaaa aagatcctgc tgaaacgctt
     4861 ggctatctgg ccagtgtgga acgggaatca gatcatccat tagcaaaagc ggtcttaaat
     4921 caaattggag aaacaaactt ttatcctgtt gaaggaactg aagttgtgaa aggcggcgga
     4981 atcgtttcaa gtgtagctgg acatagagtg gctgttggga atgtggcctt gatggaaaaa
     5041 gaaaatgtca ctctcagcaa aaaagtgcaa aaagatgtca aacggtttga acaacaaggg
     5101 aactctctcg ttttgacagc ggtcgacggt gaattaaaag tactgatggg cattcgcgat
     5161 caagtccgtc cgggtgtgaa agctaatttg caggaattaa aagacttggg cgtgaaaaat
     5221 ctagtcgttc tttcaggaga taaccaagga accgttgatg tggtcgccgg cgaacttggt
     5281 ttgaccgaag ctcacggcta catgttgccg gaagacaaat cggcttatat cggaaaactt
     5341 caacaacgtg gtcaaattgt agcctttgtt ggagatggcg ttaacgatag tccgtcctta
     5401 gctttagcag acattggaat cgcaatggga agcggaacgg acgtagcgat tgaaacatcc
     5461 gatgtcgttt taatgaactc gaacttcagc aacttgcctc acgcattagg attagtaaaa
     5521 gccaccgcaa ataatatgaa acaaaatatc gtgatttcag ttggagtagt gttggtcttg
     5581 ttgaccagcg tcttcttcag cgaatggatg aatatgtcta tcggaatgtt ggttcatgaa
     5641 ggtagtatct tggtggtaat tttcaatggc atgagattaa tgaagtataa gttgaaaggt
     5701 cgaaaagaac aaaaagaagt atcagcacct gcagagaaag taaaaatatc ttaagaataa
     5761 attagaagag gctgagacaa tagtccatcc ttgaaatgac aaaagcggaa actcagattt
     5821 ttaaatctgg gattttccgc ttttttgagt tcttgaaaaa aa
//
LOCUS       DAFLWZ010000117         5779 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000117 DAFLWZ010000000
VERSION     DAFLWZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.122"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..813
                     /locus_tag="L1V38_002713"
     CDS             <1..813
                     /locus_tag="L1V38_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1317186.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="L1V38_002714"
     CDS             807..1229
                     /locus_tag="L1V38_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317187.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="L1V38_002715"
     CDS             2363..3331
                     /locus_tag="L1V38_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1317188.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="L1V38_002716"
     CDS             3341..3829
                     /locus_tag="L1V38_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1317189.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="L1V38_002717"
     CDS             4125..4406
                     /locus_tag="L1V38_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317190.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="L1V38_002718"
     CDS             4408..4824
                     /locus_tag="L1V38_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317191.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="L1V38_002719"
     CDS             5438..>5779
                     /locus_tag="L1V38_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1317192.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2154 a          980 c          948 g         1697 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 agaggggcta cttggcatag tgtacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DAFLWZ010000118         5769 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000118 DAFLWZ010000000
VERSION     DAFLWZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.123"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(1014..1304)
                     /locus_tag="L1V38_002720"
     CDS             complement(1014..1304)
                     /locus_tag="L1V38_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317193.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="L1V38_002721"
     CDS             1706..1942
                     /locus_tag="L1V38_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317194.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="L1V38_002722"
     CDS             1949..3901
                     /locus_tag="L1V38_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1317195.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="L1V38_002723"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="L1V38_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1317196.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="L1V38_002724"
     CDS             complement(4797..5489)
                     /locus_tag="L1V38_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1317197.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1893 a          997 c          917 g         1962 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttccagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacg
//
LOCUS       DAFLWZ010000119         5462 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000119 DAFLWZ010000000
VERSION     DAFLWZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.124"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..138)
                     /locus_tag="L1V38_002725"
     CDS             complement(<1..138)
                     /locus_tag="L1V38_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1317198.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
     gene            372..635
                     /locus_tag="L1V38_002726"
     CDS             372..635
                     /locus_tag="L1V38_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1317199.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            635..907
                     /locus_tag="L1V38_002727"
     CDS             635..907
                     /locus_tag="L1V38_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1317200.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            984..1313
                     /locus_tag="L1V38_002728"
     CDS             984..1313
                     /locus_tag="L1V38_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1317201.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1303..1589
                     /locus_tag="L1V38_002729"
                     /pseudo
     CDS             1303..1589
                     /locus_tag="L1V38_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1875..2732
                     /locus_tag="L1V38_002730"
     CDS             1875..2732
                     /locus_tag="L1V38_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1317202.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            2733..3281
                     /locus_tag="L1V38_002731"
     CDS             2733..3281
                     /locus_tag="L1V38_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317203.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            3541..4269
                     /locus_tag="L1V38_002732"
     CDS             3541..4269
                     /locus_tag="L1V38_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1317204.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKLQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNRSIILNDP
                     NWSKQANLREISMPSAWEETKGSKDVKVAVIDSGIDYQHEDISGNVDESLGYDFFDDD
                     TDPMDTMGHGHILPGLLVIKQTTN"
     gene            4299..5426
                     /locus_tag="L1V38_002733"
     CDS             4299..5426
                     /locus_tag="L1V38_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBN1317205.1"
                     /translation="MVPIRVFGSSGGTSLAIFTEAINYASQKGFPIINFSIGSVVYSS
                     TEEAIKNYPGLFVAAAGNNGIDMTDKPFYPASLDIPNIITVGNSSGYERSSDSNYSKT
                     GVDLFARGFRVFSTFLGSKYTYMSGTSMATPHVTGSAALALSLDPDLSTDELKKIILN
                     SVDSFYELSDLCLTGGRLNTNNVVRQVTGKLTASNITLRLNSEWSDEIAKEMCHVHWI
                     DQSGNDLTDQVVVLKNEVDTSNFGDYEVVFASPDLTDQISVTVTVPRLRKLTLGKETA
                     TIDIGSAWDSVIAIDTFQVKAIDDFGNDVTNQVQVTINADIDTINSIQAVIKFEVPEL
                     GLAQIGRLNITAKNSTINGLNEVSIEHVKKIMSFSKKNLDI"
BASE COUNT         1968 a          724 c         1120 g         1650 t
ORIGIN      
        1 cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat tgtggtatat
       61 gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat aatgttcagt
      121 atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac tactctatgc
      181 gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa attaactagc
      241 accacgggta taaaggaaac ggataacact ttacaatgct gttttggtac tccaatttaa
      301 acaaaacaat cgaatttacg tacttaatta agtacgttag aatggagata taaattagag
      361 ggggagtaga tatggcaaaa acagtcttaa atcctagctc agcacggaaa aatttttata
      421 agttgttgaa agatgtaaat gagaatcata cggaaattga aatcattagt gagcgcagtg
      481 aaaataatgc ggtgcttatt ggtttggatg attggaaagc aatcaaagaa acgctattac
      541 ttgagcaaat aggcactttg ggtgttgttc gtaagcgaga aaaagatgat agtggattta
      601 ctaatgttga tgaaattgat tgggataact tataatgaat aactattctg tgatgattaa
      661 aaactcggct aaagctgatt taaagaaaat caaacagtct aatttgaaac ctcaatttga
      721 gaaggttatt cagactttaa aggaagatcc ctatctccct acccaatcat ttgagaagtt
      781 aaaacctaca catgaaggta ggtattctag aagattgaat agacaacacc gggttgttta
      841 taaggtagat gaagatgaac acgtggttga aatttattca gcaaggacgc attacgagtc
      901 acagtaatta cttgtaaata cattatctcg tggtataatg tatttactaa gtaattacat
      961 actgttagaa atgagggatt taaatgatta caaaaacaag aaaacaaggc aattcaatca
     1021 tgttgacagt acctaaagat tttaatgttc ctaatggagt cgaagttgaa gcaaagttgg
     1081 tagagaatgg tattctttat gaatttgttg aaccacaaaa agaattttat gattttagcg
     1141 aagatatttt gtctgatata attgcagaag gctacgataa agatgagatt cttgtagaat
     1201 ttaagaatag aaaaaacaaa atgcattctt cctttagaga tattgctgaa gatacactta
     1261 ctaattctaa agtaatgact aaagaggagt tggcaacaga aattggctta tgaaatcgtt
     1321 ccttcaaaac atgtcattaa gtatttaaaa agctaaaaga gaagccattg aaagaaaaat
     1381 ttttgaattt aatttatgat gaaattgcga ttgatccata taagggtgaa caaaaaactg
     1441 gggatttatc aggtatttgg tctagtgggt tcaaatatgc gggcacaaca tatagagtag
     1501 cttacgagat tatagaaaac aaggttattc cagtattgtt atgtggaacg catgaaaact
     1561 tttatgaaca gttgaaaaaa ttaatctagt gatttgttgt cgttcttaag aaggacggct
     1621 tcttttttat cgaaaatctg attcgtctac atgactaaag tcgcgagtat tctctgcttc
     1681 tcgataaatt aaataacgtc attactttga ggaaagctat aaatcaatat atttcagctt
     1741 ttccttattt atgtactacc ttttacttat taattataag gtagtacata tatatctttt
     1801 ttttggtagt aactaaaaat aaatatgtta taatagtatc aaatgaatat tgctaaaaga
     1861 aaagaggtag gaacgtggta gcgaagaaat atgtaatcgg taattttaaa ggtggcgtag
     1921 gtaaaagtac gtgcgcgcaa atgttagggt ttgaatcagc agttaatgaa ggaaaaagaa
     1981 ccttgataat tgacttggat atgcaaggaa atacttctga tgtgatgaac ttaacgcata
     2041 tgaacttcac taacgaagaa ggaggcggag aaggtgaacc gattgtttac gaaaatactg
     2101 tgactgacgt gttgataaac aatcttccac ctaaagaggc tgtctataaa gtaatcaata
     2161 acctctatat acttccagca gacatgtcct ttgaaatgta tgatgattgg atcaaagacc
     2221 aatataatga ttcattatcc caattcaaat atatgaaaga aaagctagaa ccattatttg
     2281 atgagtttga cgtcatctat ttagatgtcc caccttctat ttctgtatat agtaaatccg
     2341 cgatgtacat tgcggattgg gcaatcgtcg tcttacagac ccaagtaaaa tcgatgagaa
     2401 atgcgatgca atatcttgag tatatggact tttttgtgaa agaatttgat acaaatttat
     2461 atgttgctgg tgttattcct ttcatgttgg aaagcggtga cgcagtagat caggaaatgt
     2521 ataaacaagc ccaagagatt tatggggaac atttgattaa aaatgttgta ctcaaaaatg
     2581 cgcgcttaaa acgatacgac ggatcaggta ttacgatgga gaagacaaag aaaggtctct
     2641 taaaacaatg ggatcgcaaa agccacgaat tatttatcag tattttgaaa gaattggaag
     2701 aacacgagaa ttggtatgcg gaggtggagt aattggctga catcaaagga cttgatattt
     2761 ttgggaacaa caaaggactc gccaaaataa aaaaagaagc agaagcaaag aaaaagcagc
     2821 aagcaattac accatctgaa aataagcaat tagaagtgca ccaagttcaa gaaataaaaa
     2881 cttcctccaa tgttgaaaga cagagtagag gaagaacaaa aaaagttggc gcaccaatca
     2941 gaaagtttga taaggtttat tccaccaagc atcctttaaa actgtcgact ttgttaaatg
     3001 cgacttccag agttttagta gaaaagtatg agactaatat gacaagagat gaattgctta
     3061 gaaaagcttt agatgagtat attaaacaga atcttacgca agaagataag caagatttgt
     3121 ttaatgacgt ggtgaaagaa ctagacttgt tcagagaaaa atatccaatt gttccagaat
     3181 tagatgatcg tggagaaata ataagaacta ccagtcagat aaaacaagat accgaagact
     3241 cactgcgcaa agggtgggga atgaataata aagttagata ataatcaaag aagaactaag
     3301 taactacctt taaacggtag ttacttagtt cttctttgat ttgcgtgaaa tagaggggat
     3361 ttatttttct ggttacgtga ttaaaaaatc caaaaaatga gcataggaac ggttatgatt
     3421 ttagggtgtg ttttaatgag atattgtgat ttcattaaca agtgtatgat aatctgttgt
     3481 tgagttagta aataagtaat agagctaact ctaaaataaa actattagga ggagatgtag
     3541 atgaaaaagt ttaaaaagaa aatatattta ggattggttg ttggggtgag tatgtttggg
     3601 ttcatggctc atactaaaca agtaactgca gatactaacc aaaaagaaag gattatgagc
     3661 caattagatg actctcaaat agagtatgta cccaatgagc taattgtcag tttaaaggct
     3721 acacaaagaa tttcaacaga gaaaaataaa ctgcaaaatt tattgggtgt aaaagttatg
     3781 gtggaaaaag atttgactct taggacaaat gaaagcgatt ataataagcg agatcaagta
     3841 ttattagtga aattgaacga agaaattagt gtggaagagg cagtaagaac atttaatgct
     3901 tctgatatgg tcaattatgc agagccaaac tatgtggttg aactagagcc gttgaatgat
     3961 gttgaggagc caaatacaac tgattcttta ggaaatcgat caattattct taacgatcct
     4021 aattggagta aacaagctaa tttaagagag attagcatgc catccgcttg ggaagaaacc
     4081 aagggttcta aggatgtgaa ggtagcggtc attgattcag gaattgatta tcaacatgaa
     4141 gatatttctg gaaatgtaga tgaaagtttg ggatacgatt tttttgacga tgatacagat
     4201 cctatggata ctatgggaca tggacacata ttgccgggat tattggtgat caaacaaaca
     4261 acgaattagg tgttgctgga ataaattggg atgttacgat ggtacctata cgtgtatttg
     4321 gtagtagtgg aggtaccagt ttggcaatct ttactgaagc tattaattat gcatcccaaa
     4381 aagggtttcc aattatcaat tttagtatag gtagtgttgt ttatagcagt acagaagaag
     4441 caattaaaaa ctatcctgga ttattcgtag cagcagctgg aaataatggg atagatatga
     4501 ctgataaacc tttttaccca gcttctttgg atatacctaa tattattact gtaggaaatt
     4561 ctagtggtta tgaacgaagt tctgattcaa attatagtaa aacaggtgtt gatttattcg
     4621 ctagagggtt tcgtgttttt agtacatttc taggaagtaa atacacgtat atgtcaggta
     4681 cctcgatggc aacacctcat gtcactggta gtgctgcatt agcgttgtca ctagatcctg
     4741 atctatctac tgatgaatta aaaaaaatca ttttaaatag tgttgattca ttttatgaac
     4801 tatctgattt atgtcttaca gggggaagac taaatacgaa taatgtcgta cgacaagtaa
     4861 cgggtaaact tactgcatct aatatcacat taagattaaa tagtgaatgg tcagatgaaa
     4921 ttgctaaaga gatgtgtcac gttcactgga ttgaccagtc aggaaatgat ttgacggatc
     4981 aagtggttgt tctaaaaaac gaagtggata catctaactt tggcgattac gaagtagtat
     5041 ttgcatcacc tgatttaaca gatcaaatct cagttacagt gaccgtacct cgattacgta
     5101 aacttacgct aggaaaagaa acagcaacca ttgatattgg ttccgcatgg gatagtgtca
     5161 tagccattga tacttttcaa gtgaaagcta tagatgattt tgggaatgat gttacaaatc
     5221 aagtacaggt tactattaat gctgatatag atacaattaa ttcaattcaa gcagtgatta
     5281 agtttgaagt tccagaatta ggcttagccc aaattggtag actgaatatt actgcaaaaa
     5341 atagtacaat caatggattg aatgaagtta gcatcgagca cgtaaaaaag attatgtcgt
     5401 tttcgaagaa gaatttggac atttagaggg tgatacgatt gtcggcatcc accataaaag
     5461 tg
//
LOCUS       DAFLWZ010000120         5326 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000120 DAFLWZ010000000
VERSION     DAFLWZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.125"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            118..1107
                     /locus_tag="L1V38_002734"
     CDS             118..1107
                     /locus_tag="L1V38_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1317206.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="L1V38_002735"
     CDS             1089..1550
                     /locus_tag="L1V38_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1317207.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="L1V38_002736"
     CDS             1600..2064
                     /locus_tag="L1V38_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1317208.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="L1V38_002737"
     CDS             2078..2827
                     /locus_tag="L1V38_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1317209.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="L1V38_002738"
     CDS             2827..3657
                     /locus_tag="L1V38_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1317210.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="L1V38_002739"
     CDS             3657..4304
                     /locus_tag="L1V38_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1317211.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="L1V38_002740"
     CDS             complement(4402..5178)
                     /locus_tag="L1V38_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1317212.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT         1825 a          722 c          958 g         1821 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaaa tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tattgtaaag ttatatgact ttataatact tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtatcaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgcatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttaataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgacttca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgc taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtaaat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaacgt cgattgtaaa attaagctag acaactaaaa agatcatttg tgctacactc
     5281 aaaatagttc cgaccaaaga attaataagg agtgagtaca aatgac
//
LOCUS       DAFLWZ010000121         5312 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000121 DAFLWZ010000000
VERSION     DAFLWZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.126"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V38_002741"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V38_002741"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBN1317213.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="L1V38_002742"
     CDS             complement(1297..2133)
                     /locus_tag="L1V38_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317214.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="L1V38_002743"
     CDS             complement(2317..3534)
                     /locus_tag="L1V38_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1317215.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="L1V38_002744"
     CDS             complement(3683..3862)
                     /locus_tag="L1V38_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317216.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="L1V38_002745"
     tRNA            3917..4000
                     /locus_tag="L1V38_002745"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="L1V38_002746"
     CDS             complement(4240..4818)
                     /locus_tag="L1V38_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317217.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="L1V38_002747"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="L1V38_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1654 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DAFLWZ010000122         5146 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000122 DAFLWZ010000000
VERSION     DAFLWZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.127"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            111..1157
                     /locus_tag="L1V38_002748"
     CDS             111..1157
                     /locus_tag="L1V38_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1317218.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1171..2250
                     /locus_tag="L1V38_002749"
     CDS             1171..2250
                     /locus_tag="L1V38_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1317219.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            2293..3693
                     /gene="wzy"
                     /locus_tag="L1V38_002750"
     CDS             2293..3693
                     /gene="wzy"
                     /locus_tag="L1V38_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBN1317220.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            3739..>5146
                     /locus_tag="L1V38_002751"
     CDS             3739..>5146
                     /locus_tag="L1V38_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBN1317221.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAV"
BASE COUNT         1831 a          607 c          935 g         1773 t
ORIGIN      
        1 aaatgcaaat ataaagataa ttggaaagga attagtgcta agtttgcatt gaaaaacaaa
       61 tgggtatttt taatttatat ttataacaaa ttgataaaga ggtaataata atgtcagtta
      121 agattagtgt aattgtacct tgttataatg ttgaaaaata tattgatgag tgtataaata
      181 gtttgataaa tcaaacattg aaagatattg agattatttt gttaaacgat ggttcaacag
      241 ataatacgtt ggcgatatta aagaaatatg aaaagcttga ttctagaata aaagtttacg
      301 aacataaaaa tatggggtta gggccaacta gaaatcgagg gatcaaaata gctaatggag
      361 aatttttggc ttttgtggat tctgatgatt ttgtttccaa tactatgttt gaaagtttat
      421 ataattgtgc aattgcagag aatgcggaca ttgcaattgg agaagtaggc attttttctg
      481 atagagaaat agaaagagta aaaataagaa aaagtctaac gaacttaaaa acaattgaat
      541 tagcaacata taacaagaaa gaatttttta agcaattcta tttcaatcgt ttatattcac
      601 ataatgcttg ggataagata tatagacgta gtttagtatt agagtttaat ttatcatttg
      661 gtgataacaa aataattttt gcagaagata attggtttca attacaagta tttatgacaa
      721 atacaagaat ctgtttcgta gataaattgt gttattatta tcgccaacaa aataattcta
      781 taatgcataa gccaaaaagt aatttggttt ttagacatgg aaatatgatt gctgattatg
      841 aaaagttgat aaggcaaaat ggaaacaaca taatagataa aaaagcttgt atgttggttg
      901 catttgatgt actaattatg gagattttta atcaaaaaaa cgttggtgga acatgtgaag
      961 attataagaa tgcattagtt tctttgaaac atcataaaat attgagagaa aatatttcaa
     1021 atatagttag aatgaaagca tatgaacttg aacctaatat gagaaagaag ttagcccttg
     1081 tgaccattag tataatgttt aattttaaaa tgtataaaac agcgtataat atgctctgga
     1141 gaatatataa tcgataaaga ggtaggaaat atgaggaaat tgacctttgt gataggaatt
     1201 atgggaaaag gaggggcaga acgagtaatt gcgaatttgg caaataattt tattcaagat
     1261 aactgggaaa ttgatattat aactatatat gggaatcggc aagactatga actgaataga
     1321 aaaatacagg tacatccaat aatatgtaaa agttcgtttc gtgcatttag acctttggaa
     1381 cgctttaagg aacttaggaa aaaaataagg gaaatacagc ctgatctggt tatttcgttc
     1441 cttgctgatg taaatatcca tgtcattatt tcattgttag gagtaaaaca aaaattaatt
     1501 gtttctgaac gaaatgatcc acaacggaat ccagaagaac catggattag gaaaattaga
     1561 gattttcttt ataaaaatgt agatggaatt gtttttcaaa caccagacgc aaaaaaatat
     1621 tttagtaaga tcaatgataa aaaagtaaaa acaattataa ttcccaaccc aataaaggaa
     1681 aatttacctt attataataa aactacaagt agtaaaaaat ttattactgc atgtagattg
     1741 gataaacaaa aaaatttgcc cttaatgatt gatgcaatag gaaaacttat tcatgaagga
     1801 tatgagtgtg aactggatat ttatggagaa gggggattaa aaaccgagct tgaaagttat
     1861 atcaaccata atggattaac agaatttgtt catctaaaag aatttacaaa taaaatacat
     1921 gaaaagatgc aaaatgcggc aggatttgta atttcttctg attatgaagg tatatctaat
     1981 tctatgttag aagcactggc tattggagtg ccagttatcg ctacagattg tccagtaggt
     2041 ggcgcaagaa tgtatttagg tgatagaaat gaaataggtc atcttgttga atgtaataat
     2101 ctagataagt taacagatgc aatgcgtagg gtacttttgg atagagaaag tgtggtaaga
     2161 aaagcgcaaa aaggaattaa actaagaaaa gaactgacat ctaaaaatat ttcaaatata
     2221 tggtacgaat atttaaacca gttcttttaa ccaaaaggag gatattgtgt gaaagaaaaa
     2281 ataaatatat tgatgttttc gttaacgtta gtcgcgttta caatattttg cgctttttca
     2341 ttaaatcaga actattggct aaattggctt ggaatattga tttacttata tgcaatctgt
     2401 acatggcatt ggagaaaagg agattcaata ttttcattat acacgatttt tttcactctt
     2461 tttttattat ttagttatgg gcaatgcatt atgtgggcat tcggtattgg aacagatcgt
     2521 ggaatcggta caacagtagt agcttatggt acggggatta ttcctagtga atcagatatg
     2581 ataatggtaa aatggtattc ttgtatttct atgtttgtat ttcacatagg agcactctta
     2641 tttacgagaa aaaccacact aagaaaagtt agttggtatg aatctggaga tgctgatgcc
     2701 gatagaaagt ttttatttaa aatagggtgt atcatttcta taatagtagt accgatagtt
     2761 tttgtttcta aattactaga ggtacgtata gcattagtcc atggttataa tgcattatat
     2821 tatggtgatt atgctacaca aagtggatat ttacaaatta ttctatatct tttttttcca
     2881 gccttaatat gtttattaat tggtagcaac ttttcaaaag taataacgag atttgttttt
     2941 attatttttg ctttatattc tttattagga attatgtcag gagacagagg aagttggttg
     3001 tatagctcta ttatactcat atgggcatac actcaatata aaggaacctt taattataaa
     3061 aaattaataa agtggcttat tttagctgtt ataggaatat atattctaaa cgtaataacg
     3121 aaagcacgtg atggtggagg actaagtaaa cttactttaa aagattttac atctgtattt
     3181 gattcagatg attctccttt agttgattct ttttttgaaa tgggggggac tatgagtatt
     3241 ataacttttt tcctaataag tggtaatgga atatatccct ttgctaatac ttatttgacc
     3301 tcactcttag gctctatatc aacaagaatg ctatcaatgt ttggaataaa gtttgtttta
     3361 ttagctgatt ggttttctca ggattattta ggaatcactt gggggactgg attctcaatg
     3421 attgcagaag cctatgtcaa tggtggatac attgggggta tagtctatat ttttattatt
     3481 ggtatagtca tcggtaaaat cctttctaat agtatagaca accaagatat tgaaaatcat
     3541 cctatgaaga tgtttttggc tataactaca gcaaatatta taatgggttt tcctagagct
     3601 gcttcatatt taattgtgaa aaattttgtg tatggtgttt taattatatt gttgataaac
     3661 tttttcctac agcaatttaa taaacgtctt taatatttaa gcttaataaa aagataaaac
     3721 aagtcaggag ttgcaaaaat ggaaagaact gctcggctca aaaaaaacac tatttgggct
     3781 ctggtgtttc aaataacttc tattgtctgt ggtatgatct tgctacgttt gatattaaca
     3841 aagtacggat ccgaggttaa tggaatgatt agctctatta accaatttct acaaattatt
     3901 tcttttttac aattaggagt aggcgctgta atgcaatcaa ctctatacaa accactagca
     3961 gaaaaggata atttaatgat aagtcaaatc ttagcttctg gagggaagtt ttatcggcaa
     4021 attgcatata ttctactagt atacgtgggt ttgttacttg cagtctatta tgttctcgtt
     4081 cctaatgaat ttgggagatc atatacaatg gcaatgattg caacattaag tattaattca
     4141 tttgctcaat attattttgg tattgttaat actttgttat taagtgctga ccagaaaatt
     4201 tatattacgt atattgcaca gacaatagca tttatttcta atacagttgc atgtgcttta
     4261 ttaattagtc tgaacacaga gatccttatg gtaaaactta ttactgctat aatttatctt
     4321 gcttgtccaa tatattatag atggtatgtg gatcgaaact ataatataaa gaggaatgtg
     4381 tcatatgata aggaaccgat ccctcaaaaa tggaatgggg ttgcacaaca cgtagcttct
     4441 gttgtactag atagtactga tgttgtagtg ttatctatat tttctaacct gatatatgta
     4501 tctatatata atgtgtacaa tttagtaata tacggagtaa aacagctatt catggctatg
     4561 acaaatggcg ttcaggcctt actaggggaa ctttgggtca gaaaagaaat agaagttctt
     4621 tacaaaacat ttgcatggtt cgaatggatt gtacatactt tgacagtttt tatttttggc
     4681 tgtaccggta tactaatcgt tccatttatt caagtatata caagaggagt aacagatgct
     4741 aattataatc aattatcatt cgcagcttta cttgtaactg ctaacgcact tcactgtctg
     4801 cgtacacctt atcatgtaat gataaaagca gctggtaaat ataaagaaac tcaaaatagt
     4861 tttataattg cttctttgtt aaatttaggt ttatcattaa ttttggttaa accactaggg
     4921 ctagttggag tagcattagg atctctaatt tcaatcacat atcatacact ttggagtgca
     4981 aattataatt caaaatattt gcttaaatgg ccgatgaaaa aattctataa acagttattt
     5041 gtaaacatct taactgtagt tctttctttt ggggcgacat cacaattgaa aatgatgtca
     5101 atcacatatt tggattggat tgttctcgca attaaatgtg cagtta
//
LOCUS       DAFLWZ010000123         5060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000123 DAFLWZ010000000
VERSION     DAFLWZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.128"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(110..1279)
                     /locus_tag="L1V38_002752"
     CDS             complement(110..1279)
                     /locus_tag="L1V38_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBN1317222.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            complement(1350..1900)
                     /locus_tag="L1V38_002753"
                     /pseudo
     CDS             complement(1350..1900)
                     /locus_tag="L1V38_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            complement(2103..2582)
                     /gene="rlmH"
                     /locus_tag="L1V38_002754"
     CDS             complement(2103..2582)
                     /gene="rlmH"
                     /locus_tag="L1V38_002754"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBN1317223.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            3010..4299
                     /locus_tag="L1V38_002755"
     CDS             3010..4299
                     /locus_tag="L1V38_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBN1317224.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(4338..4943)
                     /locus_tag="L1V38_002756"
     CDS             complement(4338..4943)
                     /locus_tag="L1V38_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBN1317225.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         1559 a          932 c          849 g         1720 t
ORIGIN      
        1 aaaataacca cccgaaggtg gctgaagaat aagcttttat ttgtaagttt ccagaatagg
       61 ttgtgtcaat aattatgtgt aaatggaaaa gcccattctg ttgatcaagt taaaacattg
      121 attctaatgt atcatgtatt tctttaaaac ctttatgaac tcggcataga aacttttgat
      181 tatagttgtt gaattgagat actagaaatc tctccagaga ttcttcatta ggaaattgct
      241 cttttctttt ggtatatttc tttaattgtt tgttaaaacc ttcaatcaaa ttagttgaat
      301 aaatagttct tctgattgac ggagggaaat tataaaaggt taatatagca ggattcatga
      361 gcaatttaac cactcgtgga tactgctttt tccatttatc tatcataaac cttatttgat
      421 tatttgcttc ttcttttgaa cttgcttggt aaactaattt gaaatcgcta cagatttctt
      481 gtcgatcact aacacgaacc ttatgagcga tatttctaga tatatggaca caacattgtt
      541 gaaattgagc atttggataa acactatgaa tactatcgtc aataccactt aaaccatctg
      601 ttacgactaa caaaacctct tctaaaccac ggtcttttag atcttgaaga atctctttcc
      661 aaacataagc agattcagtt ggagctatag taaatcctag aacctcttta gttccatcca
      721 acctgatacc aattactata tagacagctt cttttgatac ggtttgtctt tttaagggaa
      781 tatgagtagc atccataaaa atgactgagt atttagcttc taaagttctt tctttaaatg
      841 ccgaaacatc ttcagacaca attttactca tatttgaaat agtttgtggt ttgtaataat
      901 gaccatacat tttttcgatt agatcagaga tttcggacat agtaattcct ttttgaacta
      961 gctgaataat agtggtttct aaagagtcat tggttctttt ataagcaggt aaagtttgtt
     1021 gagaaaagtc tccattccta tctctaggta ttactaaatt caattcaccg tactctgttt
     1081 taaaagagcg cgaataattc ccattacggg aattacctga attaaatcca gctctatcat
     1141 acttttcata gtcaagaaat accgttaatt cagcttgtaa taaagcgtta atagccaatt
     1201 ctaggtgacg acgaaacaaa tcatccaaat cacctttatt gattagtatt tccataattt
     1261 ctgtagtaaa atcgttcata tggaagtcct cttttctgtg aatgtgttgt ggtaactcta
     1321 ttctacagaa gggacttcct tttttctatt tacacaaaat attttacact ctcttcaacg
     1381 atattcttgt aagtaattat gccccaacta ggatttgtgg gttcatttcc atctggagtt
     1441 aaaaaaacaa aaattttttt atagttagaa taattgcgtt ctatatatat ttggtattta
     1501 ttaagttgcc ctccagactc cgaagacaga attttatttt cgatgcacac cactatttta
     1561 tttttttccg ataccaataa aatatcaata ttcttatttt ctctgtaaac aattaaatct
     1621 tcatagctat taagtaaagc atcaaaataa ttgatagcag ctttggtatc atcattagaa
     1681 tctatatacc ttttcaaaaa cattttaaaa aactcatcag ataaattgtg ggtttcattt
     1741 ggagcaaaca aaaaagctaa aaaattacta tgtcttattt catttttaga tagcttaagt
     1801 atctgaaata tatttgtttt cccagtccat ttagatagtt ttcttcaata tcatccatat
     1861 cctctaatag attttttaaa cacttttttt catctatcat gttttttctc cttgccatta
     1921 ttctaactaa aattttacgt atttgtttct atgtctacat tatcttttta acagtatcta
     1981 tttttctttt gcaacttact tggctaccaa agcaaataaa aaagttattt ataaatttct
     2041 ccctaccact acctattgct attatttaaa atagggataa ttttttctct taaaaaatat
     2101 cattatttgt ggtatggagc ccccgcattg atccggaagg cacggtagat ttgctcgaca
     2161 aggatcagac gcatcaattg atgtggatac gtcatttttc caaaagagat ctgagcattg
     2221 cttcttttca tgacggcttc gctgagtcct aaagagccgc cgataacaaa aacaaggtgg
     2281 ctttttcctt ggatacctaa ttggtcgatt tgtttagcaa aagattcact tgtaggattt
     2341 ttcccttcaa ttgctaaggc atagacgtat tcttgttctt tgattttcgc taagatccgt
     2401 tccccttctt tttcttttac ttgtctcatt tgcgcttcgc ttaaattctc cggggctttt
     2461 tcgtcaggaa cttcgatcaa ttcgattttt gcataggcat tcagccgttt gacatactca
     2521 ttgatacctt ggatcaggta tttttctttt aattttccta ctgagataat tttgatattc
     2581 atgttttctc tcctttggtc ttcatgctca ctttgtttat tataatcaat tttttcgtct
     2641 atatgtttat tttggctatt tttgttaaaa agatttcccc aacagttatg cacaacatcc
     2701 acaggtttat ccacagaaaa cagtgttatt ttaccttatt tcatcacatt cattaggcaa
     2761 acatacgttt tataagaatt tatccacttt atacacaggc tgtggatatg ttttatccct
     2821 tatttttcca atcctatccg cgtagtttta cacagtatct gtggaaaaag aaaatcaaat
     2881 attttcatct gaaaacaatg atttttccta aagtttttca taaaaagttc acagtctcaa
     2941 agtagactaa agtcaacaaa taagactata ctaacagtag ataaatgaat gtaattggag
     3001 gaggaacaca tggatagaaa aaatgtgaca ccaaagatga aaaaaagtaa aaataatagc
     3061 ctctggcgta agttaggtct ggggcttgtt ggagggatcg ttggaggact actgacagct
     3121 ggcatttttt atgcagcgat gggcactggc aacaatagtt ctactgctac aagcggcaat
     3181 cagaattctg ccggtgaaac agttgtggaa aatgtcaaag tcaatgtaga ttctgatatc
     3241 accaaagcgg tagataaagt tcaagacgct gtcgtttctg ttatcaactt acaaagtcaa
     3301 aaccaatcaa gcggttttgg cggactattc gggcagcaag aagaaagtag cagctcagat
     3361 gatagtaatt tggaagctta tagtgaagga agcggcgtga tctacaaaaa agacgggaat
     3421 actgcttatg tagtcacgaa taatcacgta gtagatggcc agcaaggtct tgaagtcttg
     3481 atgaaagacg gtacgaaggt aaaagctgaa ttagttggaa cagatgctta ttcagattta
     3541 gcggtgttga agatcaattc agacaaagtc gaaacagttg cctcttttgg tgactcaagt
     3601 gctctgaagg ttggtgagcc tgcgattgcg attggttccc cactaggatc tgaatatgca
     3661 aattctgtca cttcaggaat catttcttcc ttgaaccgac aagtgacaag tacgaatgaa
     3721 tcgaacgaaa cagtcaatat caatgcgatc caaacagatg cagcaatcaa ccctggaaat
     3781 tctggtggtc ctttagttaa tatcgaagga caagttatcg gtatcaactc aagtaagatc
     3841 gcaagtactt ctgaatctac ttctaatgta agcgtagaag gaatgggatt tgctattcca
     3901 agtaacgatg tagtgaatat catcaatcaa ctggaaaaag acggaaaagt gacacgtcca
     3961 gctctaggta tcacaatggt cgacttatct gccgtttcta ctcagcaaca agaacaaatc
     4021 ttgaagattc cttcatctgt aactaacggt gtcatcgtga caaatgtcca aacagctaca
     4081 ccggctgaaa aagctggatt gaaacaatac gacgtcatta ctaagatcga tgacaaagaa
     4141 gtttcttctg gtgtagaact tcaatctgct ttgtataaga aaaaagtggg agattctgtc
     4201 aaaatcactt actatgaagg ctcgaaagaa aaaacaacta ctgttgaatt gacgatcgat
     4261 caatcggcat taaaacaaaa tcaaaatagt gaaaattaat aaaaaagagg ttgtgacaaa
     4321 gacttgtcac aacctcttta ttttggaaat gcttctccga ctacggcatc ctcaggcaat
     4381 actaagattc ctttttttgc tggagcattt ggcaaatgca attcacgagc ggaacagatc
     4441 attccatagc tatctacccc tcgcaaagtt cctggccaga tcatcattcc atctggcatc
     4501 atagctcctg gttttgcaac gacaactttt tgtccagctt cgatattggg tgcaccgcaa
     4561 acgatttgca atactgtacc attgtctact tctgtctcag taatcgataa atggtcagaa
     4621 tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga tcttcggttc atgatcagct
     4681 tcaagctgtt cttcgaatcc tgcttctttg atcaatcgat tcaatttcgc taattcctca
     4741 tctgttaagc ttacttggcc gttcccttcg attgttagat gatcggagat atggaaaaag
     4801 ttccaagcaa caacttgacc ttgttcatct ttgatccgag caacattcca tttgcgttca
     4861 acagtgtttt ctgttccttt atcgtcggct ataataacca tcaaggtgtc tccgacgtgt
     4921 gctttgttat aagcaaaaat catgttcttt cctccattat cctttgctga gatttatctt
     4981 aacaaaaaat tgcattcact gcatgaaatt tttttcatgc tttatttccg aagaagcctc
     5041 ttctggaaca ccatttattc
//
LOCUS       DAFLWZ010000124         4931 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000124 DAFLWZ010000000
VERSION     DAFLWZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.129"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            83..970
                     /locus_tag="L1V38_002757"
     CDS             83..970
                     /locus_tag="L1V38_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1317226.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="L1V38_002758"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="L1V38_002758"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBN1317227.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="L1V38_002759"
     CDS             2272..2718
                     /locus_tag="L1V38_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1317228.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="L1V38_002760"
     CDS             2991..4343
                     /locus_tag="L1V38_002760"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBN1317229.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="L1V38_002761"
     CDS             4514..4801
                     /locus_tag="L1V38_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317230.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1395 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt t
//
LOCUS       DAFLWZ010000125         4927 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000125 DAFLWZ010000000
VERSION     DAFLWZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.130"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(238..1257)
                     /locus_tag="L1V38_002762"
     CDS             complement(238..1257)
                     /locus_tag="L1V38_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBN1317231.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1254..1478)
                     /locus_tag="L1V38_002763"
     CDS             complement(1254..1478)
                     /locus_tag="L1V38_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1317232.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1475..1768)
                     /locus_tag="L1V38_002764"
     CDS             complement(1475..1768)
                     /locus_tag="L1V38_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317233.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1805..1942)
                     /locus_tag="L1V38_002765"
     CDS             complement(1805..1942)
                     /locus_tag="L1V38_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1317234.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1944..2375)
                     /locus_tag="L1V38_002766"
     CDS             complement(1944..2375)
                     /locus_tag="L1V38_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317235.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2389..2883)
                     /locus_tag="L1V38_002767"
     CDS             complement(2389..2883)
                     /locus_tag="L1V38_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317236.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2883..3332)
                     /locus_tag="L1V38_002768"
     CDS             complement(2883..3332)
                     /locus_tag="L1V38_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317237.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3336..3956)
                     /locus_tag="L1V38_002769"
     CDS             complement(3336..3956)
                     /locus_tag="L1V38_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317238.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(3956..4864)
                     /locus_tag="L1V38_002770"
     CDS             complement(3956..4864)
                     /locus_tag="L1V38_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1317239.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
BASE COUNT         1341 a         1066 c          783 g         1737 t
ORIGIN      
        1 gaccggacgg ttatgagccg tctgctctga ccaactgagc taagggtact ggttgttgcc
       61 acataaagcc ataaacaatc aaccagtaga atgtgtggca acaaacctgt tatcgcatag
      121 cttggagtgt gactattatg ggtgatagtg aagatatgcg ataacatcac tattttatcg
      181 aatgattttt atagttgtca atatagttat gtaatgctcc tcaacgagga gctattttta
      241 tcgtttagga atatttaaat accaacgttt gtcatggaaa tcttgcgcac cgcctttagt
      301 gtttccctct ggatcattcg ttgcccgcat catgacatag actttcttat tagggaagtt
      361 acgcatgtta aaagatacat gatagccaac atttccagaa gtattataag cttgatttac
      421 atctgctcta taaattccat cagctcttac tcgagctaat tctttcccag tattgtaatc
      481 cataatgaag atatactcgt atttatagtt agcaatgtgc catccagcta catgcaaatt
      541 tgcattttcg atttctccaa actgatcaat gtgggcgtaa ttcgttccat ctgtcagtgt
      601 aggattagct gcaccagctc gtgttggatc aatgacaggc ttgttttcag aagttgttgg
      661 attttcatcg gtaaatccat gagctaaatc atatgctaat ttttctttac ttacgcccat
      721 ttcagaaaga taaccgtaag gatctgtatg atcgccccag atgttttgtg ttacccataa
      781 atgcgatttg attcccggtt ggttataagg agtgtccaac gttaatggaa taccatattt
      841 cattgctgaa tctctagcca attcaacgta tgccttgtag tttttctcaa acgttgcttt
      901 atcatgtgtg tgttgtaact caatctgcac aggactgttg gcattagcat acgaaccagc
      961 accgtactgt acataaccag gttgaccgac ttgataaaca attccgccgt ctcccacaat
     1021 ataagcagta taagcgctag tccatgaacg ttgcatatac tgcgcttcat tgcgtcctgt
     1081 tgctgtttca ttagccgttt catgcagtaa aatatactga ttatttgcta cttgtgagct
     1141 accttcattt gcgcccaaat taaattcatt gttgatagta taggcaaatc cgttaattgg
     1201 caataaaaaa agagccgtta acaggctcat cgcagtaata gtaattttct ttttcatttg
     1261 tttcctcctt cttcgctttc agccgagaac attttgtagg ttcgatttga tacacccaac
     1321 acactcccta aaaacgcgcc aaaaccagta atgatgacaa cacagatatc tgtgtactgc
     1381 caattgagcg ctttaccaac taaccccacg aaagtagcta gtgcgggaat aattaccagt
     1441 gcgaaccatt ttagtacttc gaacgtttta ttattcattt tcttctctcc ctaaacaaag
     1501 ttttgatttg ttgcgtgtgt tccaccaatt tttctgtatg tgtatctaat ctttcatcgt
     1561 gtttctttag ttcttcatga atcatcaatc gatctgattt gctcgattct aaatctttag
     1621 tcagcaaatc taaattgtgg cttacttttg aaagagtctc agtaattttc gagaaagatg
     1681 cagcaatcgg tctaattact aataaaatca aagaaacgat agcggttatt gatcctgcta
     1741 tcattcccca ttcccctaaa ttaatcatgt gacaactcct ttaccttaaa taaaaacgca
     1801 tcaattaaga tgcgctctta tctttattaa tgattttatc tgcttcttcg tctgtaatgc
     1861 ataatggaac gaaaaccatt acttgttcgt tagtgaaaca gccccagtca tacattagtt
     1921 tgatatcttc atatgaatac atgttacttc ccaccttgta attgtttttt gatttcttcg
     1981 atttccttgg tattttgtac agaagcaagc atcgtttttg aattcaactg cgctaaactt
     2041 tctgactttt ctttcaataa gacattttct tgcttgattg ctacattgtt tagcattgct
     2101 ttagaattta gctgtttcaa ttcatcattt tctgccttca gcgtttcgta taatgcctta
     2161 atattagcca attcatctac gctatcaaca gcattccctt ttttctcttc ttcagtagct
     2221 aactcaaccc actgtttttt atcaaaatca aatcttggtc tccagttagg aactggtggt
     2281 ttaatctctg tacagttttc agggatattt tcttgattgt tcaaaatgat ttgctcgaat
     2341 ccgtaaggct tgattgattt gtaaactact ttcattagat ttcctccctt aaattgaata
     2401 agtgataaca aatgaataag ctgatccata acttgaattt cttctccatt taatggctcc
     2461 gtctgcgcca atagatagtt gagcactgtt caaagtagaa cggtctattg acccaaccag
     2521 ttgttcaaaa ctaattggtg tccgatagcc ttctggaaca gttaaaataa ccgaatcatt
     2581 cccgccacta ctttttccgt ttaaagccac aaaatatata gaaactgttt ttccttcacg
     2641 ataaagcttt gctgtccctg tattaccgtt agtgacaacc agatttacca cttcatatct
     2701 gttatcatca gtcgtcaaaa cacgtttatt attgattgtt acagaacctg aaaaattctt
     2761 atgtcctgca atggcttggt ctccatctgt ctgcaccaat gcttctttac catcaatagc
     2821 ttctacatgc gtttttaagt atttagcaac tccgtcttct tttaattgaa caatatcagc
     2881 cattaaaccg tccccacttt ctcaaatgta atattcgcta atccatcaag tttcacttta
     2941 tcggttgctg acattaaacc tgctgtcgta gttgtagcat tacctggatt tttctgtgct
     3001 ccagctgcaa ttccatccaa cttagtttta tctgtggacg acatcaaccc atttgctgta
     3061 gttgtagcta cagctgtagt tgtggcattt attccaggat cacctttatc tccctttggt
     3121 aaaacaaaat taaatctagc tgcagatgat gttcctacat tcgtaacaga agcggttgaa
     3181 ccactagaaa cggttcctat ggtaattgtt gctgcttggc caggatcgcc tttatctccc
     3241 ttcaccgttg ttggtttgcc ttctatagca ttccaatgag tttgtggata aacctgtaca
     3301 ttgctttgtt ttatttttac gatatctgtc attctctata cctccccaat tttttcaaaa
     3361 gtaaaatttg gaattctttc gtttgtgtaa ttttctgctt gatttacagc ttcttggaat
     3421 ttttgatcta catatgactg attgacacca ccagtcccac taccacctgt agaactaatt
     3481 gttccatctt catcaatagt gatgttttct ccagcagtat aatttttcag tgaatcgagt
     3541 ttttctttta actccagcga aaaattgaca tcagattgtc tgactgcaga gactttccct
     3601 gtctcatcaa tcgtcaataa ttcaccaact tttatgccac ccaaacggtc gatagtggca
     3661 actggcaaca cgtagtcacc ttctccactg tttaaaattt tttgatacat ttctgccgtg
     3721 ataatgccgt catcttcttc acttgcatag ggtaattctg tgagaacatt ctctaatccc
     3781 aaatcttctt tagtaatgac gacggctcca atttttccat taacagataa aactgttgct
     3841 tctcctgcta ttatttcttc taacccaaga actgcggaag catgtgtgat tggaaagaat
     3901 tggcgttgta cacccgtttt ttcatccgtt tccatcattc gtttagtttt agccattaga
     3961 tcaccccaac tttctcaaga gtgaacacat tttgctttgg atcatcaacg gttgcgatga
     4021 tcaaggctcc ttcttcaatc gggaatgcta cagttccaac tttttcgact tcatgattat
     4081 ctgaaaagag atcatcctgc aaaatatcag tcacttcaat ctccccgtat tcaatcgtga
     4141 aaagcgttgc tcgcaatttc tgatataaat agtccatatc tgccagcaaa cgctctgaaa
     4201 tagacgcatg acgaactcct tgaatatcta ctcgcgcatc cgttagttcg gctaacatga
     4261 ctccacctgg atcaatcgtc tttaaaatat ccttgattga ttcaaaccat gccaaatagt
     4321 ctgattcttg tccttctctc caatcttgga aactgtgttc ctgttcttgt ctccaacgtt
     4381 caaattcttc tttcctttca ttcatccagt ccgtaaaatc gcctttattt tcattaataa
     4441 agtccgtcat atccgcaatt aaatcttcga ttgattgcca ataagaaccc atttctcctt
     4501 ctgtttttga aacagcatta atgacaaaat aagagaagtc ttgagttgtt ccaatcaagt
     4561 cttctccttt aaatataatg aaattggctg tttgtcgatg taaacactgc atggaatatt
     4621 tatcaaaaat atagttaatt ttcccttttt tagcatccac aatttttgtt tctaattgga
     4681 ctggatattt cccacctaca actgattcaa aatatacctt acattctgat aaatcgtagg
     4741 gaagaccatt ttcaactata gtcgcttcca taacctctgt attcttattg ccttgtcgaa
     4801 cttgaatcat ccccacgtaa ttatagggtt ctgttgtact taatatgaca ttccactttg
     4861 ccattaaatc acctccctat tttggtggta tgacaatgga agaaattgca cttgcactat
     4921 aatactg
//
LOCUS       DAFLWZ010000126         4863 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000126 DAFLWZ010000000
VERSION     DAFLWZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.131"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="L1V38_002771"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="L1V38_002771"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBN1317240.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="L1V38_002772"
     CDS             1085..2005
                     /locus_tag="L1V38_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1317241.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="L1V38_002773"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="L1V38_002773"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBN1317242.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="L1V38_002774"
     CDS             3311..4789
                     /locus_tag="L1V38_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1317243.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT         1709 a          780 c          938 g         1436 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagaaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgttt ttttcaaaga aaaggtaact
     4861 aga
//
LOCUS       DAFLWZ010000127         4813 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000127 DAFLWZ010000000
VERSION     DAFLWZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.132"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(93..1178)
                     /gene="xerS"
                     /locus_tag="L1V38_002775"
     CDS             complement(93..1178)
                     /gene="xerS"
                     /locus_tag="L1V38_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBN1317244.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIIPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3254..3772)
                     /locus_tag="L1V38_002776"
     CDS             complement(3254..3772)
                     /locus_tag="L1V38_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBN1317245.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1583 a          786 c          729 g         1715 t
ORIGIN      
        1 aatataaaaa tgataatgaa gcttgccttt aaagttgggc ttttatctaa ttttagagac
       61 aggcttcatt attatactat tttttactac atttacaaag cgttcaaagc atcaattgta
      121 gctgcattgt ctatatgagt atataaagtt gttgtatttg tacttgtatg tcccaattgt
      181 tgggcagtta ataccaatga atttgtctgt tgatagagtc tagtagccaa agtatgacgt
      241 aatttatgtg gactgacttg gactctgaat ccttttgaat attttgctac catccgttcg
      301 attgcaatac cggatatacg cttggcttct ccttgataaa ttgctaaaaa taaagctttt
      361 tcgttttctg ttactttgta tcgttctttc cgaatagcta gataattagc taaatattcc
      421 attgcaaatg ctgctatatt tactgcgtct ctcttatttc cttttctagt tactaccaca
      481 ttattctttt ctaaagatag gtcctctaaa ttaatattta caacctcgga gagtcttaat
      541 ccagatccta aaatcaatgc attgatcgcc aggtctcttt ctacatctcg ttgataatag
      601 atcaaagctc gtttgctcaa agttttttta tattcattgg caatataatc tagataattt
      661 tgtgtatctt cgtctagaaa taattttttc tcgattgcgt ttgcacgggc agctaacgta
      721 gttttatctg tgatagttgc tacttgatcc ataggattat tttctaagta tggttttcct
      781 aaaggattat tggaactttt cgaaagatat ttaaatagaa cctttaatgc tgtgatattt
      841 ctattgatag tagaagtaga tagacctaag ttattattat ctttgagctt agtttttgtt
      901 gtctcttttt ttacattttc ctttgtgcga cgtttcaaat gagatttgta caagtttaga
      961 tcataggcag ttaactgtct tatcgaggtg attgaagtat cgggaatgat agactcactc
     1021 agaagccatt cataaaagag cttataattt tttagatatt ctaaagtagt tcgaggtgat
     1081 tgatctttat cctcacgatc ttgaacaaaa tcttttatat aatcgggcat atgaagtatg
     1141 attgtatcta ttttttgata tatttctgta tttttcatgt tattcatcct ttcgataagt
     1201 aggggagagg agtatctcta taattggact ataccaatta tagagtgttt tgtcaattgg
     1261 tatactctga aatttattaa tttatttcaa aaaagcagat aaataggtat agatttaata
     1321 atttaaaata aatggtatac atgaatagga aaggaaacag aaggaggcaa tcttaatttt
     1381 ttaaattgtc taaattatat agaaagaaca atctttctat ataattagac ataagagaga
     1441 ctacggttga tttgatatta acaagcgtat atgaatgtat atacaaataa aaaaggggag
     1501 ggagaagtta aagaaaattc agagaagtgg ggcactcagt agtattaaca atttaaaagg
     1561 aatttcttaa agaaaatggg ttgcatcctg gagatacaat ttttttagat aaagaaaaaa
     1621 ttcaagcaac aattcaaaaa aatcttaact gctgagattg atgtagcaat atctcaatca
     1681 tcaacaaagt acgatcctgc ctttcaaaag cttattgata aatgtttatt cattataaaa
     1741 ataaaagaaa aatttatgtc agcttttttc atcaaagtgg taatgataat tcgtctatta
     1801 attgtatttt ttaggaaata tggtataatt gttttaacga aaaggtaatt catgatacac
     1861 caaaaaccac tagctggcgg gctagtggtt ttcttttacg ttctattcag attaacgggt
     1921 aggcttactg tcttttttgg caataatttt gcaatcaagc catttacaga tgtaatgcgc
     1981 ggatacttct gctaagattg caaaaaacat atcgaaaagg taattcataa tacaacctcc
     2041 tccccttgcc ataataggcc ggggtagcag acagcataaa tattatacca taactgaaaa
     2101 tttcatttta gtacatttca atatattgat gaaccagcac aataaaacat gccatgacta
     2161 acagaaaaaa acttattaaa ccagatataa cttgtaaaca tccaactata tagaaaacgt
     2221 aaattttcta tatagttgga ttaagataac gactatttat tttatcatat ttttactata
     2281 ccctatactt ttacttggta tatttatgaa taatcgcaaa tttaccccta tactactagt
     2341 ttgtaagtta gattaataaa aatactaaag ttatttgttc ttttattaaa tacacctaca
     2401 acttataaat tgatggtatt tagataacac gaaagaataa aaataacagc tgatagtaaa
     2461 gtttgttgac gattgctact caatcgaaag tgagttagtg cgtatgaact tgcttctgaa
     2521 aacttatgaa atgaaagacc ttttacatct tgcagaaatc gttactggga ttaaactaag
     2581 caataaaaac taatgttccc ctcattcttt gaacttctac tatttgattt atttattctg
     2641 ataaatgacg atttcacctt caggatcttc aaatcccgta tagaatttat ttaagatctc
     2701 ttcagtatca gtaataggat aggcgatagg ccacataccc tttgatggtt agaataaact
     2761 gctcaaaatc tgtatcgtat gttggcttta gcatattaac aaaggctatc tccaaattat
     2821 aaaccataag cgttgaatcg ttcttaacaa tttcaattct tcctaaccca aagtcagaag
     2881 atataattac cggacttgcc ttacccttca tgtgggttgt tgagattcca tatttaaagg
     2941 gaattgtcgg tactatcggc ggtctgaaaa acatcccaaa aataaaaaaa tctttcccct
     3001 gctagtctcc taagtccctt tgtagcggat atggcaccat aatctcattt tatcgaagtg
     3061 agtcatggtt tatctgttgg ccaaccaaaa ttgatacaat ctaacgatgc accctctacg
     3121 gcattctagg ggagtgcact tgcattcacc caataaaaac cggcagttag caaagaactt
     3181 atgtagtcgt atgttcttac tgttaacata caagaggtct cctttccaca attgcttagc
     3241 agtaaacggg aatttacaaa gctaatctct tccattttct tatctttgtt ctaaaagtcc
     3301 caaatggagc aactgtattt acatgaataa atttatatac ttcccataca gccgttttgg
     3361 ttgcctcgtc tgcccatttt cttttgtgtg cagtgaatag atcttcatca ctcattgaat
     3421 caatcatcat gttaatatca tcaatattac gattgagaat ttcctctaat tctttcaatg
     3481 gtagatgtgc ataggtattt gtaaaccact tatataactc tcctaactga ttccatttaa
     3541 attgatcaga aggcgtttta acagataatc catttctttc atcattttcc cattttagaa
     3601 ttaaattcgt ccaaccaact tgatatgcta aattttcagc aggtgttcta tccacttcct
     3661 caactctttt atccttcaat tcttcaggaa tagtttcaaa ttctaaaata tatttagtat
     3721 aagtcctatt tatttctttt tttaattctt ctttattttt atatgttctc attatattac
     3781 ctccataaat tcctaattgt ctcctttaat tcatctataa tttcatccac gatattttaa
     3841 tccgttctac aatgcatatc tgatatgcat tgactgtcta actcatatgt gaatgattta
     3901 taaaatatcc caacgtctca tctaaagaaa tgttgatcgt cagcaaggag ctaaaaaata
     3961 cgaatatatt tcttttgtag taaaatcgga ctggtttgca tatcattttc ttcgtaaata
     4021 tcaaaatcat gttaactact atcaattact aataaaaact accactttaa gcgttaagaa
     4081 ctgttaagtt tagttaagtg aggatagttc acaaaatcca ttgttaaact tcacgaaagt
     4141 ggtaaaactc aaaatgcttt atataggatt acagcatcgc tctttcttcg attgcgcgtt
     4201 gggtaaaaaa tattatgaag taaaaattga cgatgacacg ttccttacgg ctcatcagat
     4261 gaaacagcta caaaaacgaa atgatcaact cgaagaaaat ttaattctaa aaaagcgatt
     4321 gccatattca cgcctcgctc gacgaactat taaaggtcaa gatttacctg aagatcatcc
     4381 tttttaggaa attgaagctt tttatgttgc acaatgcatt tataatacta caatgatgtt
     4441 ttcaccagat attcttctag ggtgcggtgt aatgaaacag atacacttgc aaaagaaaat
     4501 tcaccgcgaa tttactaaaa ttatgaataa ttatgttaat cttccgaaat ttttttccaa
     4561 aattaaggga tcaagctggt gttatagatt gtttaaggtt ggcaaaaaaa taacttcttt
     4621 ttaaacaatt atagaaaacc gatactctgt taagttggtt gacacggtgt cgatttttat
     4681 gactttctta ttctgaaact tcactaacgg acagtaccta aaaagtctat agtatggacg
     4741 tttacgagta ctattttatc aaaaatgctg ctcatttcaa cttatatgtt ttagtgaact
     4801 acccccactt agc
//
LOCUS       DAFLWZ010000128         4739 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000128 DAFLWZ010000000
VERSION     DAFLWZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.134"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1V38_002777"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1V38_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBN1317246.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="L1V38_002778"
     CDS             complement(2066..3064)
                     /locus_tag="L1V38_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBN1317247.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="L1V38_002779"
     CDS             complement(3290..3943)
                     /locus_tag="L1V38_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBN1317248.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1V38_002780"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1V38_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1317249.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1390 a          998 c          742 g         1609 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccat
//
LOCUS       DAFLWZ010000129         4698 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000129 DAFLWZ010000000
VERSION     DAFLWZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.135"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(543..2048)
                     /locus_tag="L1V38_002781"
     CDS             complement(543..2048)
                     /locus_tag="L1V38_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1317250.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="L1V38_002782"
     CDS             complement(2045..2731)
                     /locus_tag="L1V38_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1317251.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L1V38_002783"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L1V38_002783"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBN1317252.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1327 a          964 c          777 g         1630 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa agggatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attttggctc
     4441 tataatttat gggactgatg aatcagaatt gattcttcag ccccattttt attttaggta
     4501 ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca actgagagga
     4561 cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag aaagatttga
     4621 tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc gtcgatgctg
     4681 ttttctcacc tgctcccc
//
LOCUS       DAFLWZ010000130         4674 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000130 DAFLWZ010000000
VERSION     DAFLWZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.136"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(12..482)
                     /locus_tag="L1V38_002784"
     CDS             complement(12..482)
                     /locus_tag="L1V38_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBN1317253.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="L1V38_002785"
     CDS             complement(641..1099)
                     /locus_tag="L1V38_002785"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBN1317254.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="L1V38_002786"
     CDS             complement(1270..2415)
                     /locus_tag="L1V38_002786"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBN1317255.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="L1V38_002787"
     CDS             complement(2428..3345)
                     /locus_tag="L1V38_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBN1317256.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="L1V38_002788"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="L1V38_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBN1317257.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="L1V38_002789"
     CDS             4437..4607
                     /locus_tag="L1V38_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317258.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT         1458 a          848 c          881 g         1487 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taac
//
LOCUS       DAFLWZ010000131         4591 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000131 DAFLWZ010000000
VERSION     DAFLWZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.137"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            186..2855
                     /locus_tag="L1V38_002790"
     CDS             186..2855
                     /locus_tag="L1V38_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBN1317259.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="L1V38_002791"
     CDS             complement(2946..3566)
                     /locus_tag="L1V38_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1317260.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="L1V38_002792"
     CDS             3680..4219
                     /locus_tag="L1V38_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317261.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="L1V38_002793"
     CDS             4216..4554
                     /locus_tag="L1V38_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBN1317262.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1521 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt t
//
LOCUS       DAFLWZ010000132         4459 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000132 DAFLWZ010000000
VERSION     DAFLWZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.138"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            121..939
                     /gene="purR"
                     /locus_tag="L1V38_002794"
     CDS             121..939
                     /gene="purR"
                     /locus_tag="L1V38_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBN1317263.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            1442..2815
                     /gene="glmU"
                     /locus_tag="L1V38_002795"
     CDS             1442..2815
                     /gene="glmU"
                     /locus_tag="L1V38_002795"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBN1317264.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            2909..3880
                     /locus_tag="L1V38_002796"
     CDS             2909..3880
                     /locus_tag="L1V38_002796"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1317265.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      3886..3988
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4054..>4459
                     /gene="thiT"
                     /locus_tag="L1V38_002797"
     CDS             4054..>4459
                     /gene="thiT"
                     /locus_tag="L1V38_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBN1317266.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVV"
BASE COUNT         1465 a          779 c          982 g         1233 t
ORIGIN      
        1 cttcttttta ttttaataaa taccgaacta ttttcttatt ttttcataaa atgctcgaat
       61 ttttgaagaa aaacttatat aatgtaaaac gataaaattt cttaaaagga gttggaatag
      121 gtgaaagtac gtcgcagtga acgtctagtt gacatgacac agtatttatt gaatcacccg
      181 catgaattga tttccttaac aagctttgcc gaacgttatg aatctgctaa atcttctatc
      241 agtgaagatt tgggaatcat caagaaaaca tttaaagaac gagggtatgg aaccttggaa
      301 acaatcccgg gtgctgcagg tggtgtattg ttcatccctg aaatttcata tgaagaggcg
      361 aaaaaatata ttgaatctct agcagaacgt ctatcagaac aagaccgtct gcttccagga
      421 ggatatgttt atctctctga tttgttagga gaacctgaac tgctgcgtca agttggaaga
      481 atcattgctt ctaaatacct tggtgaaaaa atcgatgctg taatgactgt agccacaaaa
      541 ggcgtaccta ttgcccaagc tgtgtcctat tatctgaatg cgccattcgt tattgtacgc
      601 cgggactcaa aaataacaga aggatcaaca gtaagtgtca actatgtgtc tggatcttct
      661 gaaagaattg aaaagatgga actgtctaag agaagtttga aacgtggttc acgtgtcctt
      721 gtagtggatg atttcatgaa aggcggcgga acagtcaacg gaatgaagag cttgattgaa
      781 gaattcgaat cagaacttgt tggcatcact gtatttgccg aatcaaaatt caacggtcat
      841 cgcgccatcg atgattatac gtcactgctt tatgtcaaag atgtagatac tcaaacgaaa
      901 aatattacgg ttgtgccagg aaattatttt tcagaataag aggttgtgaa aaagccgctt
      961 agtttcgagt agtaagaaaa attttgtgaa aatggctttc cacatttttt cataaatttg
     1021 gcttaatacc gagaaactgg cttttgaaca ccgtttatct agaggttgtg aaatcagcgt
     1081 cctgtcctga gtattagctc aataaacgga aaaattgctc ctcatatttt gccgtttatt
     1141 gagctaatac cgaaggtcag ctgattgaaa aacgtttaat gaagaggttg taagcctacc
     1201 gtttaactct aagtcacaag aaacgatttc aaaaaacagc ttttcatgtt ttatgagtag
     1261 tgtgacttgt gaccgaggag ttggcaggag agcaccggtt accaaataga taggcccgtt
     1321 atggtctatc tattttttta tccagaaaac gctgggataa aagaaaatca cttgttttgt
     1381 tgaaaaaatg ggtatactgg gataaactga aatcagcaaa ctatatttag gagtgacgca
     1441 gttggacgca cgttatgcaa ttattttggc ggcagggaaa ggtacccgca tgaagtcaaa
     1501 attatataaa gttttacatc ccgtttctgg taaacctatg gtagaacata tcattaatcg
     1561 ggtcagtgaa acgaaaccag atgaagtgat tacgatcgtt ggacacggag cagaacaagt
     1621 taaagcacaa ctaggagaac gcagtaaata tgcgttacaa gcagaacaat tgggaacagg
     1681 acatgctgtt ttgcaagctg cttctttctt ggaaggaaaa aaaggaacaa cgttagttat
     1741 cagtggcgat acaccattat tgactactga aacgctgaac aatctttttg aatatcacca
     1801 aggaaaaaat gcaagtgcaa cgatcttgac ggcacaagca gaaaacccaa caggatatgg
     1861 acgaatcatc cgtgaccata ttgggatcgt agaaaaaatc gtggaacaaa aagatgcaac
     1921 accagaagaa gctcttgtac aagaaatcaa tacaggaact tactgttttg acaacgaagc
     1981 tttgttcgat gcgttaagca aagttggaac aaacaatgct caaggtgaat actatctaac
     2041 agatatcatc gaaatcttaa aagaagaagg ccatacagtt gctgcttatc aaacggatga
     2101 ttttgaagaa tcaatgggag tcaatgatcg gatcgcgtta gctaaagcaa atgagatcat
     2161 gagaaagcga attaaccaga tgcatatggt caatggcgta agctttgtcg attcagcaac
     2221 gacatacatc gatgcaggcg tagaaatcgg tccagacaca ttgatcgaag caggtgtaca
     2281 aatccaagga aatacagtca ttggttctga ttgtgtcatc gggtcacatt caaaaatcgt
     2341 agacagtagg attgaggatc acgtcgtcat tgaaaactca gtcattgaaa gcagccatgt
     2401 caagaaacat gcagatgtgg gaccttatgc acatttacga ccaaaagctg aaattggcga
     2461 aaacgtccat atcggaaact ttgtggaagt gaaaaatgct caaatcggca aaggaactaa
     2521 agtcggtcac ttgacttatg ttggtgatgc tacgctggga gaagaaatca atgtcggatg
     2581 tggtgttgtc ttcgtcaact atgatggaaa gaacaaacat catacgactg tcggcgacca
     2641 cagctttatt ggttctagca cgaatatcat cggacctgtc gaggtagcta aaaacagttc
     2701 gattgctgcc gggtcaacaa ttacagacaa tattccagaa tatgcgctgg caattgcgag
     2761 agcaagacaa gtcaataaag aaggatatgc aaaaaaactc ccttatctaa actaagactt
     2821 ttgcaaaatc acttgattta tttaaaaaat atgactacta tttattaggt agaattctag
     2881 agttgtgaaa aagaaagtgg aggtccccat gtcaaaacat tactttgacc caagattaaa
     2941 aatttttgcg ttaaattcca atcgcccatt agcagagaaa attgcagcag cagtcggcgt
     3001 cgagttagga aaatcatctg ttactcaatt tagtgatgga gaaattcaag taaacattga
     3061 agaaagtatt cgtggatcgc atgtctatgt tattcaatca acgagcagcc cagtcaatga
     3121 taacttgatg gagttgctga tcatgattga cgcactgaaa cgagcaagtg caaaaacaat
     3181 caacgtagtc atgccttatt atggctatgc gcgtcaagac cgtaaagcac gtgcacggga
     3241 accaatcaca gcgaaattag tagcaaacat gattcaaaaa gctggtgcaa caagaatgct
     3301 gactttggac cttcatgcag tccaaatcca aggtttcttt gatattccag tcgatcattt
     3361 gatgggtgcg ccacttattg ccaattattt cttagaaaaa ggaatcaaag gcgatgatgt
     3421 tgtcgttgtt tcaccagacc atggtggtgt cacacgggca cgtaaattag cggaattttt
     3481 gaaatctccg attgcgatca tagacaaacg ccgtccaaaa gcaaatgttg cagaagtaat
     3541 gaatatcatt ggacaagtca aaggcaaaac ttgtgtactg atcgatgata tgatcgatac
     3601 agcaggtacg atcacattgg ctgccaatgc tttgaaagaa gctggtgcaa ctagtgtgta
     3661 tgcttcatgt acacatccag tattatccgg ccctgcttta caaagaatag aagattcagc
     3721 tatcgagcgt ctagttgtta cagactcgat ctatcttcca gaagatcgta aaatcgacaa
     3781 aatcgatgaa gtaagtgttg gcggactaat gggagatgca atcaaacgta tccatgaaaa
     3841 caaaccagtt agtccattgt ttgaaacaaa aaataaataa taaataaact cacaaagggg
     3901 agtccaattg ggctgagatt gaatctattt ctaaaccctt cgtacctgta tcggttatgc
     3961 gagcgtagga attgtgaata aacagctgtt tgactatttt cgaaagctgc ttcctccttt
     4021 gtgacttttt tattcaaagg aggaagtttt tttatgggaa aaaatagagt ttgggtagaa
     4081 ggaacgattg ttgcagcgtt agcgatggtg ttgtcgttga ttccgatcca gatcggcagc
     4141 agtttttcta tttcattagg gcagattcca ttgactcttt ttgcgttaag aagagggaca
     4201 aaggcaggga tgctggcagg tttcatttgg ggcatcctac attttccgtt gggacaagtt
     4261 tattatttaa gtgtcgttca agtgttgatt gagtacccga ttgcctatac ttttgcaggc
     4321 gcagcagggc tcatggcttc aaatgtccaa aaaggctatg tagacgataa tacgaaacaa
     4381 attagaaaaa gcatcgtgtt tggtgcattg attggcgcac tttccagata tttttggcat
     4441 tttattgcag gagtggttt
//
LOCUS       DAFLWZ010000133         4429 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000133 DAFLWZ010000000
VERSION     DAFLWZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.139"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1V38_002798"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1V38_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBN1317267.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="L1V38_002799"
     CDS             complement(2944..3378)
                     /locus_tag="L1V38_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317268.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4429)
                     /locus_tag="L1V38_002800"
     CDS             complement(3395..>4429)
                     /locus_tag="L1V38_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBN1317269.1"
                     /translation="DFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNN
                     LNVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSK
                     TIEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGD
                     TIRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGI
                     VYYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEM
                     HITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQL
                     GLVDNFNNIS"
BASE COUNT         1373 a          824 c          611 g         1621 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatc
//
LOCUS       DAFLWZ010000134         4418 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000134 DAFLWZ010000000
VERSION     DAFLWZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.140"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            59..913
                     /locus_tag="L1V38_002801"
     CDS             59..913
                     /locus_tag="L1V38_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1317270.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="L1V38_002802"
     CDS             1010..3259
                     /locus_tag="L1V38_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1317271.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4418
                     /locus_tag="L1V38_002803"
     CDS             3262..>4418
                     /locus_tag="L1V38_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1317272.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
BASE COUNT         1556 a          625 c          807 g         1430 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagagt
//
LOCUS       DAFLWZ010000135         4407 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000135 DAFLWZ010000000
VERSION     DAFLWZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.141"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(716..3865)
                     /locus_tag="L1V38_002804"
     CDS             complement(716..3865)
                     /locus_tag="L1V38_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1317273.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            4276..>4407
                     /locus_tag="L1V38_002805"
     CDS             4276..>4407
                     /locus_tag="L1V38_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1317274.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT         1224 a          900 c          730 g         1553 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccctccct cgtaaaatat catttgtcta
     3901 atagttttta ttcaaaatgt ttctagatta taaaatttat tgaataacac attcctaacg
     3961 gaatttgttt cgatattgtg tgatttctca gagtacaatg gatgtatgga aaggatccaa
     4021 cgggaatttg ctatttcctc ctgtagcgtt tgtctaccct gtttagtctg ttacccgaac
     4081 cactgttatc actaccaact cattagctgt ttcgataatg gactagactt tcaaatagta
     4141 gtttggaagg cagcttctag ctcttttatc accgtattct attaggcgag gttgtggcta
     4201 tacagtgagt ttctgggaaa tcccacagta tcgaagcatt ttccaaaatt tatatcgaaa
     4261 ggaggtcctt cttccatgaa attatttgtc ggtattgacg ttagctctga aaaactagat
     4321 gtttgttttt taacagacga caatcaattg tctatcttat ctgaaatctc tgttgccaat
     4381 gacatcgaag gtgcttcatt catacga
//
LOCUS       DAFLWZ010000136         4345 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000136 DAFLWZ010000000
VERSION     DAFLWZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.142"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            183..884
                     /locus_tag="L1V38_002806"
     CDS             183..884
                     /locus_tag="L1V38_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1317275.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1493..2509)
                     /gene="tsaD"
                     /locus_tag="L1V38_002807"
     CDS             complement(1493..2509)
                     /gene="tsaD"
                     /locus_tag="L1V38_002807"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBN1317276.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2506..2970)
                     /gene="rimI"
                     /locus_tag="L1V38_002808"
     CDS             complement(2506..2970)
                     /gene="rimI"
                     /locus_tag="L1V38_002808"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1317277.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2977..3519)
                     /gene="rimI"
                     /locus_tag="L1V38_002809"
     CDS             complement(2977..3519)
                     /gene="rimI"
                     /locus_tag="L1V38_002809"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1317278.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3503..4225)
                     /gene="tsaB"
                     /locus_tag="L1V38_002810"
     CDS             complement(3503..4225)
                     /gene="tsaB"
                     /locus_tag="L1V38_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBN1317279.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT         1308 a          911 c          739 g         1387 t
ORIGIN      
        1 tttatacaca aatcattcgc ttcaaaacaa attattcaat accattgtat attttttaca
       61 taataacaaa ttatatttgt aaagtattaa aacttgtttc taatgttggt atgttaaaac
      121 tttacaaatt ctttaaaaaa agtgacaata aatatagtga acaataagga gaggactttt
      181 taatgcgtgt taataaaatc gattttcact tttcaaaact cagatatcaa cctgattttg
      241 aacatttctc ggatgaagag ttccaacaga tcaaggaaca tactgttctt cgttcttata
      301 aaaaaggaca gatccttttc gacgatggtg atcccagaca acggttgtat atcttgacca
      361 aaggactcgt tcgtttagaa cgttatgatg aaagtgcaac ttattactac tatgactatg
      421 tgaatacaaa taaccttttt cctatgtcag gaatgtttgg agaagagacc tacacttata
      481 cagctcaagc gatgactgat attgaaacat tctaccttcc tgtttcctac tatgaaaaat
      541 tagcacgaaa aaatcccgaa cagttgatct atatgataca aaaaatttct aaagtagttg
      601 aaatacatga attgcgtatc caaatcggat tgacctctag cgcctttgac cgggtaaaac
      661 aaaatttatt cattttgaaa gaagaattgg gcgtaccaac aaaagatggt catatcacca
      721 ttccttatcc gatcacctta aaagaattag cagtgaatag cggcacgaca cgtgaaactg
      781 ctggacaagt aatcaaacaa ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt
      841 ttactttctg taagacagct actactccag ctatgagaga ataacgcgaa caaaaataag
      901 cagtgaccct gataaatatc agggtcactg cttattttcc tccctaaaac ttctgaaaga
      961 tccggcagtt ttagatcact ggacaagact caaagatttt ctatgtgtgt ttcagttatg
     1021 taatattcac tgtttgcaaa aaatactgtt agattaacta gatgaagcgt cttgtcctca
     1081 tccgatctag attattcgat attcctcgac aataaacgat tactcagtga gggcaatcag
     1141 aggaacggat aatgataaat aagctgtaaa aaatagcaaa ataacaataa tgattaaaag
     1201 tatgtaaaaa atagggcttt gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt
     1261 gtacctgtca actcttcggt cacaagtcat aatgttcata aacatgagga gctgtttttt
     1321 gaaattgttc cttgtgaatc agagttaaac gacaggctta cgaactcttg attaaacggc
     1381 gttcaaaagc ttgcatacgc ggtaataaga acagccaggt caaaaacatg agaagccgtt
     1441 tttcctgggc tgttcttatt acttgatgca gggcagcttt ttcacaacct ctttattcag
     1501 ataaaaccaa gcttggatca gcattcaact gatagctagc aaaatttctt ttttgcattt
     1561 ccacatgtgc tgctgctcca atcattgcag cattatctcc acaaagtcga agagggggaa
     1621 tcactagttc tacctcaggg agtttagctg ccaaagcatc ctgcaatcct tcacgcaacc
     1681 cttgattggc cgctacacct ccagctataa tcagttgctt gactggataa ttttgacaag
     1741 ctcgaagtgt tttagtaatc aatacatcga tcacacttgc ttgaaagcta gctgctaaat
     1801 catttttgtc tagatcttct ccacgctgtt gtgcattatg caccaaattg ataaatgcac
     1861 tttttaatcc gctaaaactg aaatcataat tatcttcatg gatcatcgct cgcggaaaat
     1921 ggtaattatc ttttccctga tgagctagct gatcgatttc ttttccgctt gggtaagaaa
     1981 gacctaatac tcttccaact ttgtcataag cttctcctgc tgcgtcatct cttgtctccc
     2041 caatgatttc atatgatcca tcttcttgca tatagactaa ttctgtatgt cctccgctaa
     2101 caagaagtgc catcaatgga aactggaatg gtttaaccag acgggctgca tagatatgcc
     2161 ctgccatatg gtttacagga ataagcggca attggtgtgc ccaagcaaaa gccttagctg
     2221 cagaaatacc aatcagcaac gagccgacaa gtcctggtcc ataagtgaca gcgactgccg
     2281 ataaatcttc tgccgacaca ccagcttcta ccagtgcatc ttccaagcat aaggtgattt
     2341 gttctacgtg atggcggcta gctacttcag gtactacgcc accaaaacgt ttatgactgt
     2401 ttatttgaga agcaacgatg ttagataaga tctctgttcc atttctaacg accgctacac
     2461 tcgtttcatc acaacttgat tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc
     2521 cgtttttaac tttctgctca taatgatcgc atcttccgtc ggattgcgat aatatgattt
     2581 ccgtttacct aatatacgaa acttttctga ttcataaagt tttcttgctg cttcattaga
     2641 tagacgtact tctaaaaaaa catgcagcga atcttttatt tgttccgtaa tcagtaattg
     2701 taacaaatgc cgtgcatgcc cttttccttg ttctgaaact gcaacagcaa tatttgtgat
     2761 ctcgacttca tctattactt tcgagtatcc aataaagcca cagatctggt tatcttcagc
     2821 taaaagcaga taatcagagt gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca
     2881 aggtgaacca tgtggataag cattttcgct aatcatccat acgcattctg ccaagtacgc
     2941 ttcatcaaaa tctttttttc tgcaaatcaa ctaatctcac tcattttcta aaagttttat
     3001 catatccaac gcatcttctt ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg
     3061 aaaccccaat ttccgataaa gtctttgtgc atcttgatta ctcatacgca cttctaatga
     3121 catcgtctca cagcgattca ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc
     3181 gattcgttta cgctgatatg ccggtcgaac ggcaatattc gtgatatggc aatctaaacc
     3241 gaacgctctt gaaccgataa aaccaatcat tcttccatta tcaaagatac ctagatatag
     3301 atgaggaagc ggtgacttca attctgatat aaaggcactt tttgtccatg gcaattcgcc
     3361 attatagact tctcgttcga catccagcag ctctttgata tcttctgtag tcaattctct
     3421 tagtacgtaa cgacgatcga tttgttcgac tgttttttct gtataaatca ttttatcttg
     3481 aaaaaagctt ctggcatacg ctctaaattt tttcaacata actttcgtct ccaggtgtgt
     3541 gcgtctccaa ccatttttct tctgcttcta ctcgttttaa atagcgagga agaaaagctt
     3601 gtttctctgc aactggttca actaaagcac ctaattgagc cacagttaca ccacttggaa
     3661 tatcccatgc tggaactgta ttaatcatcg cactaggcaa tatttccttt atttcagaga
     3721 agaatttgtg acaatcactc ccgacgaaat aaatagcttc attcagcttt tgtagttgtg
     3781 tgaacaaatc agaagcagaa atatgtacat cttcaagtac agtttctaat ctattttctt
     3841 tccagcggta tgccccagcg tatacatttt ttcttcgagc atcaaacatg ggcacaataa
     3901 tattatccac accgatgcaa ttagccgcga tggttttcag actagatact cctactagct
     3961 ctttatctaa tgtataagca atcgtttttg ctgtcgttac acctatacga agccctgtat
     4021 aagaaccggg accatcagaa accgcgattc ggtcaatgtc ttttggactt atttgaagat
     4081 ctgcaaacaa ttggtcgatt gcaggcatca gtgttacact gtggttgcgt ttgatatttg
     4141 tttgtatttg tccaagaatt tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg
     4201 cagtatctat tcctaatgta atcatatatt tgatcctttc tgctatgaca ttctcgcctt
     4261 ccattgtagc atactttttt attctgagga tgaaaatacc aaaggcaaaa ctagtacaat
     4321 aatacatgat tatctgctgg cgggc
//
LOCUS       DAFLWZ010000137         4290 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000137 DAFLWZ010000000
VERSION     DAFLWZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.143"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(176..1462)
                     /locus_tag="L1V38_002811"
     CDS             complement(176..1462)
                     /locus_tag="L1V38_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1317280.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(1455..2723)
                     /locus_tag="L1V38_002812"
     CDS             complement(1455..2723)
                     /locus_tag="L1V38_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1317281.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2975..3436
                     /gene="mscL"
                     /locus_tag="L1V38_002813"
     CDS             2975..3436
                     /gene="mscL"
                     /locus_tag="L1V38_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBN1317282.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(3495..3941)
                     /locus_tag="L1V38_002814"
     CDS             complement(3495..3941)
                     /locus_tag="L1V38_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1317283.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(4034..4279)
                     /locus_tag="L1V38_002815"
     CDS             complement(4034..4279)
                     /locus_tag="L1V38_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBN1317284.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
BASE COUNT         1213 a          877 c          757 g         1443 t
ORIGIN      
        1 gattacttcg tttgatttta ttttaatata agttgattaa aagagagcat gatttgtttt
       61 attttctcac taatttttcc aacacaacta agaataccat aaaagctgat tttggaggag
      121 gttcctacta caagtctaaa acgaaattta agacttttcc tcataaaata ctggtttatt
      181 ttggtctcat gtaaaactcg ctgaaggcct cttcacttat aaatgcttcc ccagctgcca
      241 gtacgtcttt catttggatc gaatcgatga tttcaggaag atcaaataaa gttcgatcgc
      301 caaataaact ttgcgtaaat tgattggcaa tatattcgat cgaatttaat gattggaaat
      361 attgtccaag cattttcttc ttcagcaaat cgagatttgt ttctgacact tccggatcat
      421 cagcgaatcc aagaatgatt tctttgactt tttctgctgc tttctctggt tcgtccgtat
      481 ctccgctgaa gtccgcaaag tgaaattcac gatccaagct gaattcaaaa ccaaagctgt
      541 catcgataat tccttgattg tacatcgcta gatagtttcg agaagtattg cctaaaatca
      601 tttggaacaa cagattgatt gctgttttat agcgtaacag ttctgttcct tcttgcggca
      661 atgtgtctaa tcctttaata ccaagtacaa atttatctcg tgtaatggct gcttccaatg
      721 cactttgttt gatgatttct tttgtgtttt cagggaaata acgtacaatt tcttgctttg
      781 gagggaaatt ttttgcttct tggttttccc gaataagttt catcaatttc tcaggctcca
      841 tcttaccaac tacaaataaa accatattgc ttggctgata aaacgtccga tagcacgtat
      901 acaagtcttg agctgtgatt ttgtcgatac tttcaaccgt gcccgcaata tcgatatgca
      961 atgggtgtgt aggatacaag ttatttagta tgccaaaaaa catccgccag ttagggtcgt
     1021 cttcatacat ttggatttcc tgaccgatga ttcctttttc cttgtttaca gtttcttctg
     1081 tgaagtaagg tgcttgtaca aaatcgatca gagtcgtcag attcttttct acctgatccg
     1141 tcgtagaaaa cagatagctg gttttcgtaa aacttgtgaa agcattggcg gaagctcctt
     1201 gtttcccaaa taattgaaag acatcaccat cttctttttc aaacaactta tgttctaaaa
     1261 aatgggcaat tccatctgga actttcacct tttctttttc accataggga ataaattcgt
     1321 tatcgatcga accataattc gtactgaaca aaccatatgt cttgtgatag tcatttttag
     1381 gcaacaaata cacggtcaaa ccgtttggca gtacttcatg ataaagtgtt tcattgattt
     1441 gctcatattc tgttttattc atttgcattt cctcctgcta aaaagaagat tgcctgcaat
     1501 tcgatttgct cagctacttg ttgtatctct ttgatcgtta cgctctccat acgtttcaac
     1561 cattcttcat cagataattt tgtttccggc agccagctgt ccaaaaaaga agcttcgatt
     1621 gccgcttgcg gagagtctag agaaagcaga tattggtttc tcagcattgc ttttgtctga
     1681 gacagttcca actctgttat ttcaccattt cgcaaacttt ctaattgctc gtgaatcaga
     1741 tgaagtactt gatttcggtt cttttcatcg ataccggttt ggacactcat gaatcctcgg
     1801 aacgtatcca cgctactaga ggcataataa gctagacttt ctttctctct gacattcatg
     1861 aaaagtttag agtgaggaaa accgccaaat aaaccgttaa agaccattag cgcaaaacgt
     1921 tctggttcat cgtaatacac atttgtctga taagctaggt tcagctttgc ttgaacgatt
     1981 ggctcacgta cttgtcgttc cttcacgata ttcacttgag gttgggtata aaacagatct
     2041 ggataaactg tttcccgcga ctcaaatggt aattgcccaa ctgcttcagc tgctttgtcc
     2101 ggatcaacat cgccgacaac aaaaatgtcg atttgatcat ttgccatcat ttcttgatag
     2161 taggacgcta gcgaactagc agtgatcttg tccaaatctt cgactacgcc caaccctggg
     2221 atcttttgtt ccgggctgtt ttcaaaataa agttcttgca aggcatagga agcaaaagtt
     2281 tgtttatctt ccttcaaact ttccaaatat agacgcagat tgttcttttc caagtcaaac
     2341 gtcaactgat caaactgatg atttttaata tttggataaa ataaaacctc ttttaaaaaa
     2401 tctaccgctt gagaaaaaag gtttggatca ttgacatatt caccattcac aaaactgatc
     2461 cctgcgttta gccaatgtaa atttcctttt tttctaactg ataatccaaa gcttgcgcca
     2521 taaagctctg caagttgcgc acttaacttt gtctgatccg aataattcaa actatttgtt
     2581 tccaacatgc tgctgagaag tgaacgtttc gtgatgactt cttgttgcag acgcgcagta
     2641 aaacggataa aaatccggat cgttttgtat tgttttgttg gtaagacatg aagattcacg
     2701 ccttctgcca attgatacac catatttata tgctcctttt cacagttgat tgcccgctta
     2761 ctcttttaat gggtcaacct gcctttttta cttattcctc tgcttgaaat ttataagttc
     2821 aggcaattcg ccgttttttc taaatgatgt tacactttat agtatagcat agatgttttt
     2881 tatcaaaaga aacagacggc taaaagcgta tattgttttt ttatttttta tttttcgata
     2941 tactaaagac aaataaaaga agggagggtc attcatgatc aaagaattca aagagttcat
     3001 catgcgtgga gatgtcttgg atcttgctgt cggcgttgtt attggtagtg cgtttacaag
     3061 catcgtaaac caagtggtgc aaggcttgat cacaccacta ataggttggt ttgtcgcaat
     3121 gatcacaggt acttctgatt tagaaggagc actttcaatt cttgactggt cgccgacaaa
     3181 aggcgtcaca tttgcgtttg gtaacgttat tagtgctatc attacatttc tgatcactgg
     3241 ttttgtctta ttcttagttg tcaaagcggc aaaccgtgcg aagaatttac gctccaaaga
     3301 agagcaagtg gaagtggaag aaactcctac tgcagaagat tatcttagtg acatacgcga
     3361 tcttcttgcc aaacaagtgg cagaagacaa tacacatcca gtagagcaaa caaatctttc
     3421 cgatacttct aaataataaa gaatctaaaa aaaagaaagc cgattttcag tgtcggcttt
     3481 ctttttttag attcttaact tgctacttgt tcctttttca tgtcgatatg tggaatatca
     3541 tcttccaaat acacatctga gattgccttg aatccaaacg actcataaaa agcttgtagg
     3601 tattcttgtg cgccgatcac gattggtttt tctggaaaat ttttctggat catgttaatc
     3661 gtttcttgaa caatctttct tcctaaacca tctttacggt tgtcctgatg aacaaggaca
     3721 cgtccaaaat ggatactctc cgcttcttca tatactcgcg tgtaggcaag gatcttccca
     3781 tcagtatctt gaaaaaacgt atgccaagct tctccatcaa tgtcatcaac ttcttgataa
     3841 ggacactgtt gttccacaac aaaaactgcg attcgttctt tgacgatcgc gtaaaactct
     3901 gctgttgaca attcttcaaa tttctttacc tgatattcca ctaagcaaac gccccctgct
     3961 tttttattct tagcataccg attcgcacac aaaaaagcaa acgaacctta cgaatctcag
     4021 gctcgtttgc tttttaaact gcttcagtta aaaattcgat ctcaactgtc cgagtaagta
     4081 catctgaata gctgtaagat actcgttcaa aagaattttc ttcaggatcc aaatcaacaa
     4141 cgaatactga aggataggtt tctgttaaaa cgccgcggcg ttctgtttga cgctttcttc
     4201 ctgtctgagc aaccaacatg attgggctgc cgatacgacc ttctaaatct ttcttgattg
     4261 aagctaaagt tgttggcata cagttcacct
//
LOCUS       DAFLWZ010000138         4219 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000138 DAFLWZ010000000
VERSION     DAFLWZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.144"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            144..1445
                     /locus_tag="L1V38_002816"
     CDS             144..1445
                     /locus_tag="L1V38_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1317285.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1472..1732
                     /locus_tag="L1V38_002817"
     CDS             1472..1732
                     /locus_tag="L1V38_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1317286.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2731..3966)
                     /locus_tag="L1V38_002818"
     CDS             complement(2731..3966)
                     /locus_tag="L1V38_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1317287.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1219 a          672 c          872 g         1456 t
ORIGIN      
        1 attttcagga ttcttaaaaa taaatttgat tatttaagag aatatattga aataaaattt
       61 cttaattata taattagtta tgaacattct ttgcgttgtc atgcaatgaa tggttcatat
      121 tttattgaaa aggagtggtt ttagtggaaa agctgatgaa atgggtcgaa gagaaacttg
      181 tcccaccaat ggcaaaaatt ggtacacagc gtcatttatt agcaattcgt aatggggttg
      241 tttcaacatt gtcattgatt ttgattggga cattttttat ggtctttatc aatttaccgt
      301 ttcctggatg gaatgaattt attgcccctt attcggcaac gattgtttta ccctttagga
      361 tgacgatggg attgatggct atttatgcaa cttttgttat gggttcggat ctagctaaat
      421 catatggatt agatagtgtg acaggtggta tattatcttt aggaacgttc tttatgttac
      481 aagttcctgt aaacgtttta actcctgaag aggcacctct tggctgggtc ttacctatga
      541 gttctttggg agcatctggg atgtttgcgg ggatcttatc tatgattttt gcagtggaag
      601 tatatcgttt ctttaaaaat cgaaatatta ctatcaaaat gccagaacaa gtgccacctg
      661 ctgttgcccg tagttttgag gcattgattc caggtgcagt cattttaaca attacttggc
      721 tgattcgaag cgtcgcgggc tttgatgtaa acgctgcctt attatcgtta ttcgagcctt
      781 taaccaatat tttagggaat aatttgcttg gtgttttact accaatgttt ttgatccatt
      841 tgttgtggtc atttggtatc catggcatga gtattgtagg ggctgttgtt cgtccaatgt
      901 ggctgatcat gttggatgag aatgcaaagg cattggcaga tggtacagct gccacccaat
      961 taccctatat cgctcctgaa cagttttatc aatggacggt aacaattggt ggtgcaggag
     1021 caacgatcgt ggtatctgtt ttgtttatat tcttctgtaa atcaaaattc ttgaaagagg
     1081 ttggtcgttt ttctattatt cctggtatct tcaatatcaa tgagcccata atttttggag
     1141 ctcctatgat gttgaatcct tacatgttca tcccgttcaa cttagttcct ttagttttga
     1201 ctattatcag ttattttgca gtcaaattag aaatggtcaa tagatttact gttttgccaa
     1261 catggacatt accagctcca atcggcggtt atctttcagc aggaaatgac tggcgtgttg
     1321 ttatcttgat catgatcaac acattgatag catttattat ctattatcca tttgtaaaag
     1381 cttatgataa aaagatgctg tcagatgaac aaagtcgtgg agaaaacgaa gtccagactg
     1441 tctaagtttg gtttttagaa ggtgggaaac aatgtattgg ctgattttat tttttgtttt
     1501 tatcttttta ttaacggcta gtcaccttat attgaatatg ctagctacat atcatattca
     1561 aatcaatcga tggatttggg cactggcatc atttttgatc gtgattcttc caaagatcat
     1621 tgtaccgcat atgaatgttt tgttttcatg ggggacatat gtactttgtg gaatttttgc
     1681 tatcaatttt atgatcgagc agcatagatg gtttgtcaca tcgaagcttt aaatgttcta
     1741 aaagtggttg taacagaagt ggttagcttc aagaaataag aagaaattta cgaaaattgc
     1801 ttcttaaatt tttgtgaaat gttggcttat ttttcgtttg gttgaactta ttaccgcaga
     1861 tgcaagcttt tgaccaccgt ttattcggaa tatgggactg tgacaaggct tttgtcacag
     1921 ccctttttta cataaagatt attattgttt taactgtttt ggcagaaaga aggaggaaaa
     1981 aatggaaatt ttatcagcaa tggatttaga attagtagat ctactaccaa agtgatcaag
     2041 tcaaatatag atttgggagc ttacaaccat atagtagggg ctgcagtatg gtgtatgaat
     2101 ggtaatatgt atgatgtgag tgtttattca aatcatgaaa cgtgtataga aataattgtg
     2161 ctgggaatag caatcagtca tggtgaacgt gacttttagt gtatcgttgc tgacgacata
     2221 gaacattctg acatgatcta ctcaatatgt ggggattgct ggcagtttat ataggagtat
     2281 gcatcggatt gcgagatcat tgtctcaaca gaagagggag gttgattatc aaagataaag
     2341 tggtaaatcc tacatttgat ttagtaattg ttgaggggac tagcggcaca aatctctaca
     2401 aagcgatgct tctagatcta tatgacacat tttaagaaaa tgtatttgcc taattattat
     2461 ggtctttctt ttgaagaaac gttgagatga tccaaccaga gaaaggtgtc aaagaatttg
     2521 actaagaata aatggcagac gctacctatg ctcatttgga tagcgtcaga tcttttattt
     2581 taaggatgat tttgtgtttt ttagacaccg taatttaagt aactctaact tttcaatcca
     2641 ctatttactt tttttgtatt ttcactgtct gggtctcgaa tagcgaaatt actgatgagt
     2701 ctctattaaa aaagcttttt ctacttgaaa ctatattggg tggttgctca ggaaggtttc
     2761 gatttcttga attgcttgtt gtggaccatt tattggaaaa acggcttgca gcgtgcgtgc
     2821 ctgctgacga atcttgggtg aagaaacttc gcgcagagca atctgcagtt ttctttcagt
     2881 cactggtttt gtgagggcga ttgcgtttcc gtattttaca caatagtcaa tattacagct
     2941 ttgctcaaat tgcatcccca caccgataaa cggtttgccg gattcacagg cagtttggac
     3001 ggtcccttcc ccgccgtgga taaaagaaaa atcaatgaat tcatgcaaaa gatgactaga
     3061 cagatattct gttattaaaa gatcttctga gtcagattga atgtcatcaa gcagatagtc
     3121 aataggtgca ataaccgcta gatccggttg tttttgtaag aagaacaaaa ttttgcgtaa
     3181 catacgcgga ttgcctgaac tacccattgc gaaatagata atacgttttc tttcttgttg
     3241 ctttcgctgt ataaaagtta gcacttcttc aggcaaggaa gtactgagct tagcaaaaat
     3301 tggaccaacg attcgataat tttccggcag ctgttcttct tccaaaaata gtttaggcgt
     3361 tgtgatgaga tttagatcag catccatcat ttgtaaactt gtttttggta aaggaagcat
     3421 ttctttttgt gcagcgtgtt tgaaggcatt ggggatccat cgggtattta ctatacgctt
     3481 ttttgtccag tgccaaaggg gattgcttaa agggccgaag aaacgtaact cgtggggcat
     3541 cagcgcatgc tctgattgaa aaaaaggttc actcaaagca tagggtttaa catatactaa
     3601 aggaatcttt ttattgcggg ccgataaaaa aattgtcaca ttcgaacctg tcacaatcag
     3661 tcgaggctca aacttagcaa tcagactctg ttcactagtg atacgagagg caaccatttc
     3721 tttggtaaaa gggtttttaa gtgtacgcaa ctggtcaaat tttatgattt gttcttcttg
     3781 ttttttcgta aggatcggcg ctagtaaatg atactcaaag ccactttctg tgatcaaagg
     3841 agcaaaagtt ttagaaaagc caaagaatac acagtaataa cggtctttca tagctttggc
     3901 aacctcaatc attcgtgttg tctcagctaa attgaatact gcaggagcaa aaagaattgt
     3961 cttcatgaaa tcctccttat tggaatgagt ctatcccttc gtttcttact agtatactaa
     4021 aaaacacagc gttcgagtag cctatgtata ttttgaatat taaactgtct ctcgctgttt
     4081 tcacaacttc taaatttaaa ttttgtaatc aagttgaaac tccaattttc aaaaaaacac
     4141 gcaacaattt tttgatcgat ttatatgttg tgccagataa atacgagaag ttgtgtcatt
     4201 aaaaataaac atgagaaca
//
LOCUS       DAFLWZ010000139         4070 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000139 DAFLWZ010000000
VERSION     DAFLWZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.145"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            86..1435
                     /locus_tag="L1V38_002819"
     CDS             86..1435
                     /locus_tag="L1V38_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1317288.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="L1V38_002820"
     CDS             complement(1563..2153)
                     /locus_tag="L1V38_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1317289.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="L1V38_002821"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="L1V38_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1317290.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DAFLWZ010000140         3966 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000140 DAFLWZ010000000
VERSION     DAFLWZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.146"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(614..1171)
                     /locus_tag="L1V38_002822"
     CDS             complement(614..1171)
                     /locus_tag="L1V38_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317291.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1350..1961)
                     /locus_tag="L1V38_002823"
     CDS             complement(1350..1961)
                     /locus_tag="L1V38_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317292.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2074..2331)
                     /locus_tag="L1V38_002824"
     CDS             complement(2074..2331)
                     /locus_tag="L1V38_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317293.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2928..3206)
                     /locus_tag="L1V38_002825"
     CDS             complement(2928..3206)
                     /locus_tag="L1V38_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317294.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3240..3491)
                     /locus_tag="L1V38_002826"
     CDS             complement(3240..3491)
                     /locus_tag="L1V38_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317295.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1201 a          812 c          526 g         1427 t
ORIGIN      
        1 cttcttattt cttggagtta aacgcttctg tcccagcctc cttattccga ataaatggtg
       61 tccaaaagct tgcatctgcc agattatctc atttcttatg acaagctaag caaattatct
      121 ccaccaaata atttattcat atttttgact tgcgcatact aactaattct taaattttca
      181 tacaaaattt ctcaatttcc cttaacgagt aatatttatg tacggtgatt ctcactagta
      241 tcccaatcac tttttaagtt atcccgattt caattctact tcaaaaatag ttgcttttat
      301 gtatgctgtt agttgattag atggtcattt gttgagctag gtcgtttatt ttaaacaagt
      361 tgtttcttta gcttatacct atctcgtcta ccaaacgcaa gatggcaaac acaaatgcat
      421 acgcatctgt atttgccact ttgattcgta taaagctaac aactattaac tcctctcagc
      481 taatagttgc tctctttttt attcagattc atttttgctg atcacagcct agtatttcaa
      541 tggttttgaa cactaaacca aattgttcca ttacaacatt cactggctga tgaaatggat
      601 tagtagattt cgattattca aagcgatttt ctattggtgg atcgtgttcc caactaataa
      661 gacggattcc aaacctatcg tacagatctt ctaaaccact tataaatttt gcacctattt
      721 caggtgtttt attgcgtgga tattctattg ttacgccatt aaatggatac caattaggat
      781 taggctctct ttttttctgt acatctccca tagaatagtt agcactttct gggacataat
      841 atattcttcg accatcctct aattcatcta ataagatatt tcgtgatcgt ctatcacttg
      901 ctaaatgtag acgccacgtg cgataccatg ccatgctacc tgcatctgca gaaaatccat
      961 caaataatgc aacaattgta tcttctatca caatcctttc cccatctact tcatattcta
     1021 atctaaaatc aaactcccct cgggtaattt ctggtcttgg tggcttagga cccaatatta
     1081 ttctacttaa aaccgcattc gttcccagat gaaacacagc tataacaaca ataatgatta
     1141 atattttgtt tctatttgat aaatttctca ttattcgcac atcacctcta cattctcaca
     1201 tattagttcg taatactcct ttaatatcaa aatatctact ggtcgtaata atattcgcta
     1261 tgaattccta ctactcgtat aagaaaggcc aaatcatcag cttttacttg ctgatgattt
     1321 ggcttgtttc tatttatcgt aattgttttc taatcaccaa aattgttaac aatcggttca
     1381 gatatttccc agttgattaa ggtaattccg tattgtgtca aaacttcttg cgcttctccg
     1441 aaattaagta cagttcttat gtatccactt tctcctaata taaagtctac ctctctttta
     1501 aaaccttcct cgagatttct aagggctata tgtggtttta atgacattga ttgtacattt
     1561 tcccccatat aatattgcgc acttcctcga ctaaaataga ttcctagatc gtccccaaaa
     1621 ggtagatctt ctctaccact agctaatcta cttctccatc ttcgttctct tttcatagaa
     1681 cctgcgctga actcacaccc gttaaactca gctatgacag tatcttcaat tatgttaatc
     1741 tgtccatcta gttcgtattc aatcctaaat ggaaattctc cataggtgat ttccggttcg
     1801 ggtattttag gtgagattaa tgcaaagaaa ggaaatatta agcttggcaa catcaaaaaa
     1861 actcctccta tgatcacaat tcccgatgta atccaaaata taatttgtac aattctcatt
     1921 gatccattgt attccatttt attcccccta ttactattca tatccgccta tctatatcga
     1981 tcttccaatg cagagataat tgcttccata ccttgatttt ttactgagtt acctatgcga
     2041 gatatcattc tccactaagg tgcatcatat tgtctatcta acatgattaa ttctccaata
     2101 ggtgtatact cctccaaaaa caacatttaa tgcatctccc tcgacaacat aagctaccat
     2161 gtttgctgta tatgtgtttg agtctaattc ataagcagat aaatttactg tcgctggatt
     2221 aaatataatc gcattcgtat ttatagctac tgaatttgct gcttcagcac caccttttga
     2281 atgtccgatc attgtgattt caatagtagg atttacgtgg acagccctca ccgtttaccc
     2341 tgaccattat agaaatcgct tacttttttg aactacgcaa caaaggatac aatgctccta
     2401 acttcactgt ctccattttt gtccactaag gaatataaaa aataggcatt aattcattta
     2461 attcggtcac aacacgttac cttttaaatc attatactgt atctcataca ttattatcaa
     2521 taaactatta taaaaatgca aaaaatgctt tatcaatcta ttttgtaatt ggtcataata
     2581 tcattgaaat cataccctgt atcgattttt cctatgaatc tcgtctattt gtgattgacg
     2641 aaaaagaggc aagacagaca ctggaatggt aattttaccc actattttgc tccaactatt
     2701 tgtaatcgta cccacttttg aaataccgag atgatcattt taattgatat gctgattccc
     2761 aagcaaaacc ccaagaaatt aaatgctcta tcgcatctag cttcttgggt tttgcttata
     2821 taaattccaa catttaaatt ttttatgctg ttcggtctca gaaatgccgt ttttgcttat
     2881 atcacaatat caagatgtca aattattcgt gttgccgatg actttgatta atttttttca
     2941 aattgtttat taagactaat gctgtctttt tgcagatacc aatgttcgaa ctttttaaca
     3001 ttatcatatg atcctgcaag ttttaacttc ttaccattag atgttatcaa agttataatt
     3061 aaccttgcct ttttcccatt aggatctttt attttatgaa ttttctgcag gtaatctctc
     3121 ctaatggcag ctatttttac ctcatcagtg ctgataaacc attgatcatc cacatacata
     3181 ctgcctgtta tgttgtgttt ttccatttct tccgagaacg aaaagtttaa ggctcgttct
     3241 tacttccaaa gttgaatgag tccatggatt ggacttagtg tgagaattga gaacaacaat
     3301 aagaatccat atcctcccgc aaacatccct aaggctatac tgtctctcca tccataagta
     3361 ggattagaag agaaaagagt caccgtttgt aataatatga aaaggaataa tccagcacaa
     3421 acaccaaaga taacaactcc aaacattgaa tttttataca atgaccattt atttataggc
     3481 ttttctttca ttttacttcc ccctactgtt ctgttcacac ggaatgaatt caaagttcat
     3541 aagccctcct ctttgaacat atgaatacga cttgctaact atactttaaa aaagcttgtt
     3601 ttaagcggtt ataggcgagt tgtaatctct attcatctca ttagcaaata acttgccgaa
     3661 aagtctactg aaattaaagc agatagtgga agaattattt agccaggata gacactattt
     3721 gtgaaacaca tgtctttact tttgaaattc tatgatgaaa agccttggaa tacagtagct
     3781 cttaattggt aatacttttt ccattataaa taacctcttt tcattttata tttatcccct
     3841 ctaaaaataa tatctaatct aatattttaa acttatattt ccctcgctgt gctaatagag
     3901 cattactaaa taaatagaaa ctagaaaaaa gcattacgcc tgccagaata aaccaattat
     3961 ttgtat
//
LOCUS       DAFLWZ010000141         3832 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000141 DAFLWZ010000000
VERSION     DAFLWZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.147"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            96..1895
                     /locus_tag="L1V38_002827"
     CDS             96..1895
                     /locus_tag="L1V38_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBN1317296.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            2389..3777
                     /gene="ltrA"
                     /locus_tag="L1V38_002828"
     CDS             2389..3777
                     /gene="ltrA"
                     /locus_tag="L1V38_002828"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1317297.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT         1311 a          705 c          825 g          991 t
ORIGIN      
        1 tttttttgaa gaaacaacaa tcattttcat agagacttct tccataaaaa agtgctatac
       61 ttaattttgt attacaatat gaagggagtt ttttcatgag ttattcatta aattggaatc
      121 tagattctat tttttccgga ggcagtcatt ctgatgcttt gaaccaacgg atgaagcaat
      181 tggaagacca aatgaacgag tattatcacc gcgtaacaaa atggtcacct agttctgaca
      241 atgcagagca gttaaacgct attcttcaat tgcaagaaac gattacgaat ggttttaccc
      301 aatgcagcag ctatattact gcattgcttt ctgccaatgt caatgattca gatgcaaagg
      361 tcttatcagg caagctttac gcaatgctgc ctcgtctgca atcagccgaa actgtattgt
      421 caaagaaatt tgcagaaata tctgacaatg attggaatca gatgctttct caatcttcgt
      481 ttgaaacaat tgcttttcgt ttaaacgaga ttcgtcgtga tggctcacaa ttattatcag
      541 aagctgaaga aaacattata aatacgcttt ctttagatgg tctaaatgct tggagcagtc
      601 attatgatac gattgtagcc agcatttcga ttcccttcga acaagatgga caagtagtcg
      661 aattatctgc tggacaagcc ttcaataaga tgatgggcga tccagatcca aaagtcagag
      721 aaacactttt cgcagcatgg gaagaagcct ggaaagaaaa ggcacccctc ttcacggata
      781 ctttgaatca tttagatggt tttagacttt ctgactatga acttcatggt gtcacagatt
      841 ttctacaaaa accattagag tacaatcggt tgaagaaaga aacattgtct gtcatgtggg
      901 atacaatcca gaaaaacaaa caaccccttg ttaattactt gactagaaaa gctaatcttt
      961 tcggtaaaga aaaaatggaa tggcaagatc aagatgcacc tattatttta ggcgatttga
     1021 aagaaaaaac ctttagtttt gacgaagcag cagcatttat tatcgaaaac tttaacaaat
     1081 tcagtccaaa aatggctaaa tttgcccaat ctgcttttga aaagagctgg atcgaagcag
     1141 aagatcgtcc tgggaaacgt cctggtggtt attgtactga gttaccagaa acaaaagaat
     1201 caaggatctt tatgacctac agtaattctg ttaatgaggt tgcgacactt gctcatgaac
     1261 taggacatgc tttccatagc agcacgatgt gggatttacc ttctttaaat cgcgaatatg
     1321 ccatgaatgt cgcagaaaca gcaagtacat tcgcagaatt gatcgtagcc gatgctacat
     1381 taaaagtcgc aaaaacaaaa gaagaaaaaa tcaatttgct agatacaaaa ctgcaaaatg
     1441 ctttagctat gttcatgaat atccattccc gattcatttt tgaaaatcga ttctatgaag
     1501 cacggcaaga aggattagtc tcagaagata agatcacaga gatgatggtt gaggcgcaaa
     1561 aagaaggcta tcaaggagct ttagctactt accatccata tttctgggct gcaaaattgc
     1621 atttctttat tgatgacgta ccgttttata acttcccata cacatttggc tacctcttta
     1681 gtttgggcat ctatgcttac gccaaccaaa agggagcaaa ttttgaagaa gaatatatcc
     1741 atttactacg cgatactgcc tcaatgacga cggaagatct tgcgaagaaa catttgaatg
     1801 tcgatcttac ccaaccagat ttttggcaag caggtatcga catggtgact gaagatatcc
     1861 aaacgttcat ggaattgaca gaagaattta tctgatttct attttatcac aataaaaaaa
     1921 gagttagtcc agaatgggct aactcttttt gatgtgcgcc ctgcatgggt gaaaacttgg
     1981 tggtgaaagt ccactacagg cttggcagta ggaactgtta gcgaaagaca aggcggcaat
     2041 cgtgaggttg tggctgaagg aagtcggacg caaactcctg aactgacgaa cagaaactag
     2101 atacaaggct gaattaggtc ggataagtct tcatcacaag acaaagtcca atactgcccg
     2161 aaacctatac agtaaatcta gcagttacat gggaggaaag ttttcactct taccggggga
     2221 gatctcatga gggtgttgtg ggcgttgaat gaaaacaaac cagcacaacg atcatggcga
     2281 catgatggtg aatcatgaga agtcagccga ggtcatagta gtaacgacac tgaccgttac
     2341 gaaggactga acaataagaa tcttgaataa tttaggaggt gtgagaagat gcgacgaccg
     2401 cagaaaacaa gaaaacttgg ctatcatcaa agagctagtg tggaacacga agggtatgat
     2461 gaagtgcgca gcacttcttg cggtgaacag aggaaacaag atggtgtaga aaatctgttt
     2521 gggagaattc tagatcggaa taatctcaat caagcgtatc ttcaagtagt cagaaataaa
     2581 ggggcggctg gtgcagatgg gatgaccgtc gatcaactgc ttccttactt gaaagagcac
     2641 cgcgaggaat tactatccaa tttacgccaa gggaactata aacctcagcc tgttttgcga
     2701 gtagaaatac cgaaaccaaa cggcggtgta agaaaactag gaattcccac ggttattgat
     2761 cgtatgcttc aacaggcaat caatcaagtg ttacaaccgc tatttgaacc agaattctca
     2821 gataatagtt atgggtttcg cccaaatcgc agcgcacatg acgcagtgaa gaaagcaaaa
     2881 tcttattatg aacaaggtta ccgatatgtg gtggacattg atatgaaagc ctactttgac
     2941 accgtaaatc acgataagct gatgtatttc attgagcgga aagtaaagga caaacaagtc
     3001 ctaaaactga tccgtcaata cttaatgagt ggtgtaatgg aaaatggact catcacaaca
     3061 actgaagaag gaacgcccca aggaggcaat ctctctcccc tgttaagtaa catctacctg
     3121 aacgaatttg atcaagtgct agaaaatcta ggacataaat ttgttcgata cgccgatgac
     3181 tgcaatatct atgttagaag caaacgagca ggacagcgtg tgatgaagaa atccattcaa
     3241 tttctcgaag aacaactaaa gttgacggta aatcgagaaa agagtgcggt aggaagtcca
     3301 ttgaaacgaa agtttcttgg attctgcatt ctgccaacaa agaaaggtat taaaattcgc
     3361 cctcacgcaa aagcaaaaca gcgtgtgaaa agcaagctca aacaactcac taaaagaaac
     3421 cgtggaagaa gtatccaact tattttaaaa gaaatcaagc aactaatgac tggttggatc
     3481 aactactatg gaattggtga gatgaaagaa ttcatgaggg agttaaacgg ttggttgaag
     3541 cgaagaatca gacaatatat ttggaaacaa tggaagaatc caagaaccaa aagaaaaaat
     3601 ctgattcgtt tagggatcga taaagcgaaa gcgtatgaat ggtcaaatac aagaaaaggt
     3661 atttggtcag tctccaaaag tcatattctt catcgatcat taacagacaa agaactggcc
     3721 cgccaaggat atgaggacat ctccttgaag taccagttcg tacactcaac ttattgaacc
     3781 gccgtatacg ggtccgtacg tacggtggtg tgagaggggc ggaaggtcag tt
//
LOCUS       DAFLWZ010000142         3738 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000142 DAFLWZ010000000
VERSION     DAFLWZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.148"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            72..155
                     /locus_tag="L1V38_002829"
     CDS             72..155
                     /locus_tag="L1V38_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1317298.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="L1V38_002830"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="L1V38_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1317299.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="L1V38_002831"
     CDS             complement(1280..2143)
                     /locus_tag="L1V38_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1317300.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="L1V38_002832"
     CDS             complement(2145..2417)
                     /locus_tag="L1V38_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1317301.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="L1V38_002833"
     CDS             complement(2434..2643)
                     /locus_tag="L1V38_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1317302.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="L1V38_002834"
     CDS             complement(2742..3638)
                     /locus_tag="L1V38_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1317303.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DAFLWZ010000143         3714 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000143 DAFLWZ010000000
VERSION     DAFLWZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.149"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1087
                     /locus_tag="L1V38_002835"
     CDS             <1..1087
                     /locus_tag="L1V38_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1317304.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="L1V38_002836"
     CDS             complement(1305..2447)
                     /locus_tag="L1V38_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317305.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="L1V38_002837"
     CDS             complement(2452..2637)
                     /locus_tag="L1V38_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1317306.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="L1V38_002838"
     CDS             complement(2991..3236)
                     /locus_tag="L1V38_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1317307.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3616)
                     /locus_tag="L1V38_002839"
     CDS             complement(3230..3616)
                     /locus_tag="L1V38_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1317308.1"
                     /translation="MAFDFPPTQNIIEPKVLRNEAKSIRKRNANIKDNEEPLADSNEG
                     RYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDAEIGKI
                     LNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1216 a          676 c          569 g         1253 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttggttc tataatattt tgtgttggtg
     3601 gaaaatcgaa agcgattttc tactaacact tttttcttcg tttcaactca aaaagagact
     3661 cacttttggt aaaatttagt cgaccaaaac gtcaccctac caaaggagtc tctc
//
LOCUS       DAFLWZ010000144         3662 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000144 DAFLWZ010000000
VERSION     DAFLWZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.150"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..398
                     /locus_tag="L1V38_002840"
     CDS             <1..398
                     /locus_tag="L1V38_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317309.1"
                     /translation="ITLKPTGRRAEDIENRLNDWFKSMPKHLFKSMTFDCGKEFSNWR
                     SISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRDTDETFIQSVASKRN
                     HIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            515..823
                     /locus_tag="L1V38_002841"
     CDS             515..823
                     /locus_tag="L1V38_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1317310.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            850..1149
                     /locus_tag="L1V38_002842"
     CDS             850..1149
                     /locus_tag="L1V38_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBN1317311.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            1323..1874
                     /locus_tag="L1V38_002843"
     CDS             1323..1874
                     /locus_tag="L1V38_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBN1317312.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            2020..2313
                     /locus_tag="L1V38_002844"
     CDS             2020..2313
                     /locus_tag="L1V38_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317313.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            2306..2602
                     /locus_tag="L1V38_002845"
     CDS             2306..2602
                     /locus_tag="L1V38_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317314.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            2673..>3662
                     /locus_tag="L1V38_002846"
     CDS             2673..>3662
                     /locus_tag="L1V38_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1317315.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNF"
BASE COUNT         1366 a          534 c          725 g         1037 t
ORIGIN      
        1 ttattacttt gaaaccgaca ggcagacgag ccgaagatat cgaaaacagg ttaaatgatt
       61 ggttcaaatc catgcctaaa cacttgttta aatccatgac atttgattgt ggaaaagaat
      121 tttccaactg gcgatctata agtaactcga acgatattgc catctttttc gcagatccag
      181 gaacaccttc gcaaagaggg ctaaatgagc actcaaacgg cttgcttaga cgagatggct
      241 tacctaaaac aatggacttt agggacacgg atgaaacctt tattcaatcc gttgcctcga
      301 aaagaaacca tattccaaga aaatcattaa attatcgaac accattggaa gtatttttga
      361 gctgcataga taaagacata ttgtctagct taatttgaca aatcagatag tataaaatga
      421 atcaaattga atatcaaata tatattatat ccatgaagcc caatcttctt taatagaaga
      481 ttgggctatt tttatggcaa aggagggaaa agaaatgttt caaaataaag gacaacgtta
      541 tgtcacaaag ggagtaatgg acagtttgcc ggtggaatta caagctttat gttggaatct
      601 aatcgatcaa aacgttcaaa agcaatttca tttagactat cttcaaatct ttgaattttc
      661 tacggaaaaa ggaaatcaaa agttggttca tcgtcaagaa gaaccagaag caagaaaaga
      721 gtatctgatt tcacctaagc ttcgtttgaa atcagtgtct caaaaaatat gggtcattga
      781 ttcgggtgag tatcaaacga tgttattacc agaagaatac tgatatctaa aagaaaggaa
      841 cgaaaggact tgttagaaac ggctatcgaa gtactggaaa agtgtgcaca gctagtcact
      901 actcctgaag agtggggcta tgaatccgtt acgatggaaa aagaggaaat tgaaatgggt
      961 atgcttcctg aagatgttac tctaccacgt ttagtgatga cacatcttta tatttattgc
     1021 gcaccagaag atggaaaaga ctatgtagtt tatttcatta cagatattac cagccagcga
     1081 gaatttgttc gtgggttact ggtagaagga cgattggttt ggagtcagat tggaggaacg
     1141 aatgaataag atcgattatt tgagaatgat tgcgaaatgt ttagaagata tccttacagc
     1201 gattcatcaa attctgaaga aaaaaggaga aagaatatga aatattttca actagtattg
     1261 acacttataa cggcaatggt gattgaattg cttgaacaaa aattagcata ggagaaaaag
     1321 agatgattga aaaagaatta gtgaccacac aaacagaagt ttggcgagat cctcatcata
     1381 cccatcgcta tgttttcaaa cgacaatggg cgatcaaagg aaaagaagcg gaagataaat
     1441 tagcggtagt cattactatt cgtccaacag atacagaacc atttacgaat gatttgagta
     1501 tgttattaat cgaaaagaat atccgacaat taggatttac tggttttatt gctgtgaatc
     1561 ttttttcgta tacaaaagcg aaaagtcctc gggtatttcc tcgtggaaat gatgaacaat
     1621 ctttggaaat attaacaact gttttcacag aaaagaaaat caacaccatt atttttgctt
     1681 gtggttcgat tacagcgacg agtcaagtgg cttatgaaca agcgaagacc atttacgatc
     1741 aattgagtgc gaaacaaaaa aagatgacca aagtattgat aaatgcagaa ggtaagttat
     1801 cccacccact aagtattcat gttcgtaatg aatggcaatt ggcagatagt caattattat
     1861 ttcaagaaaa ataacatttt attttcttat gttacttata agtagtttta catgcttttt
     1921 gactttaaaa atacatgtga tgatacatgt tatatgaatt atcaatgtac ccagtaatat
     1981 gctattttca ttatgtaaaa aataacaggg ggtgtgtaga tggagattga tgaaacttgt
     2041 ttgagtaact cttataaaag tatgaatgac ttttttgagg aaatggaact ggattcagaa
     2101 ttgctctatc aattttatct tgcttttcga gggcaacaga tttcttttcc aatgaaaatg
     2161 tacgatcgtg agttagttag aaaaagaatc gaaaacatga tagaacagga aaaaactgta
     2221 gatatccgtc aattgacaga agtttatggt ttctctgcaa gatggattca aaaagtaatt
     2281 aaacaaaaag aaaggagacg agtacatggc taagctgatt gtattaggtg gtttaattta
     2341 cggtggatat tggttatata aatatatgct tgcgcatccg aatatagata aaggaaaagt
     2401 aattaagaca gttggggtaa tcatagttgg actcatagct ctaactaaga aaaataatac
     2461 taatagccca aaaataatga gaacttatcg ctgtagagga tgtggaaggg aaatttctac
     2521 tagttttaat ccatctgaaa gccctcaagg aagagatcgt tgtcatgctg gctatcgaca
     2581 ttcttgggaa aggattaact aaatgaacac cattgagatt aattgactga taaaataagt
     2641 acgcgaggga gaaattgaaa gggggaaata aaatgaaaaa atggttgtta ttactaattg
     2701 gaatggggat tttattcact ggttgtacat ctgagaatac gaggactaaa gagactgtag
     2761 aaactgatac aacaattgag gctaaaaaaa gtaaaacgca atcaactgaa caaactacaa
     2821 cagaaatgaa acaatctgtg gaagcaagta caagtgaaag ttcaatcatt gaatcttctt
     2881 ctgaagaggt taaaaatact ttgtgggata gtgagaaatc tactcaacta gcaatttttg
     2941 tcccacaatg gggaaagaca ttaggtcaag aatataaaag ctacaatcct cagaacaatg
     3001 taagtctgta tggtacgcct ttaccaagtg cagttattga tggaaattgg aaaatggcaa
     3061 tcaatgaagc accagttacc gtacaatggt cagaagatgg aactggtcat gcagatttca
     3121 atttagtagc agtttattct gatgtagaaa ctggagaata tttagggcag catgtatatt
     3181 tctttggctt tcaaaatgga caacctaaag tttatttaac gcaacaaaat caaggcaatg
     3241 ataaaaacta catgtacttc aatgaaactc agaaccaaca gttaaaacaa ggtttcattg
     3301 atattgtgaa tggacaaact cctcaaactc cagtagtaga agaatctact caacaagcaa
     3361 caactacaac gacacaatct acaagtagct cagcaatttc aagttgggaa gctgctaaag
     3421 aaactgtact aaataataaa gctttatggt tgtatgattc tcctgataaa aatgcatcaa
     3481 atactaattt aattagcaca aatgaatata tgaaagatct aatgcaagat gaaaatggaa
     3541 gctactattc aattaatatt gtaacggatg ataatggaaa tacaacaatg gctggtggaa
     3601 aacaattccg tgtttataca gatggaagaa tttctcaacg tattggaatg actaacaatt
     3661 tt
//
LOCUS       DAFLWZ010000145         3643 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000145 DAFLWZ010000000
VERSION     DAFLWZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.151"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            11..478
                     /locus_tag="L1V38_002847"
     CDS             11..478
                     /locus_tag="L1V38_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317316.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="L1V38_002848"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="L1V38_002848"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBN1317317.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="L1V38_002849"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="L1V38_002849"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBN1317318.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..>3643
                     /locus_tag="L1V38_002850"
     CDS             3200..>3643
                     /locus_tag="L1V38_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBN1317319.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYV"
BASE COUNT         1188 a          587 c          798 g         1070 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gta
//
LOCUS       DAFLWZ010000146         3624 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000146 DAFLWZ010000000
VERSION     DAFLWZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.152"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..781)
                     /locus_tag="L1V38_002851"
     CDS             complement(<1..781)
                     /locus_tag="L1V38_002851"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBN1317320.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSV"
     gene            complement(796..1623)
                     /gene="panB"
                     /locus_tag="L1V38_002852"
     CDS             complement(796..1623)
                     /gene="panB"
                     /locus_tag="L1V38_002852"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBN1317321.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            complement(1635..2495)
                     /locus_tag="L1V38_002853"
     CDS             complement(1635..2495)
                     /locus_tag="L1V38_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBN1317322.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            2733..>3624
                     /locus_tag="L1V38_002854"
     CDS             2733..>3624
                     /locus_tag="L1V38_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1317323.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWK"
BASE COUNT         1173 a          673 c          474 g         1304 t
ORIGIN      
        1 aaactgattt ttcaatataa tttactcttt gtaatgataa agaatcaaca acttctacat
       61 aatcaatctt tgccaaatta taagtattta tatttttact tattatctca attattttta
      121 agctgtctct ctctccatta tttaaagctt ccttagctaa agttaaagat ttatttaaaa
      181 tagtagctga agatctttcc tctaaactta agtatgtgtt tctagaactt ttagctagtc
      241 catcctcttc ccttataatt ggacacccta caacgtctat atcaatatta aggtccctaa
      301 ccattctttt aattacagct aactgttgtg catccttttc tccaaaataa gctctatctg
      361 ctggtattat gttaaataat ttacttacaa cagtgcaaac ccctctaaaa tgtattggcc
      421 tactagctcc acataaacct tctgttaatc cagttatatt aacaaaagta cttgcattgt
      481 cacaatacat ctcttcaact tcaggattaa atattgctgt tgctctacct cttgtgcata
      541 cttctatatc tctttctaag tctcttggat aactacctaa atcttcattt ttcccaaact
      601 gagttggatt tacaaagata cttacaacaa ctttatcatt ttcttttgat gcttttctaa
      661 ttaaactttc atgaccttca tgtaaatatc ccatagtagg aactaatcct acctttaagc
      721 cttgtttttt ccactctttt acttgacttc taacatcatt cactgtttta aatataacca
      781 tatttcttga cccttttaat ataatttttc taaaacatca tcacttattt taaacccatg
      841 ttctggacct ggaaaaactc catcttttac ttcctctata tattttgtaa atgctttatt
      901 catctcttct gataaattag catatttctt cacaaattta ggggtaaaat cactatacat
      961 ccccaacata tcttgatata caagaatttg tccatcacac cctgcacctg ctccaatacc
     1021 aattgtaggt attgatatct ctttagaaat taactctgca agcttagttg gaacacattc
     1081 taacactaca gcgaatgctc ctgctttttc tacagcttta gcagctctta ttaattcttt
     1141 agcagcttcc ttgtcctttc cttgtacctt aaatcctcca aatgcattaa cagattgagg
     1201 tgttaaacct atatgcgcca taacaggtat agaagccttt actatagcct ctattttatc
     1261 gcatacttct atccctcctt ctaatttaac aacctgagct cgtccttctt ttattaatct
     1321 tcctgcatta actactgaat catatactga agtttgataa gacataaatg gcatatctgc
     1381 aacaactaaa gtgttcttag ctcctcttgt aactgctcta gtatgatgaa tcatgtcttc
     1441 cattgttact gaaagtgtat cttcatgtcc tagacatacc ataccaagag aatctcctac
     1501 taatattcca tttatcccag cttcatcaat tatttttgct gttgaatagt cataagctgt
     1561 aagcattgtt aatttttcat ttcttaattt agattcttta aatgtaactg ctgtattttt
     1621 catctatttc tctcctaact ctctcctaaa tacttttcta attcactata atctctatta
     1681 atatttttta acatagctat ctctaataca ttttttgata atagcatata taaagctctg
     1741 tcttcatctg ataaaacttc acagtgacct ttaattgttg aaatatcaca acgttcaact
     1801 ggccctgtca aactttctat aattcctttt tcttttatat ttctaatatt aaattcaatt
     1861 aatggatata aagcttcaat tgccattttt tcagtaaatc cacattgaat tagatatgta
     1921 acgcttgtat taataagtcc tagcacaagg ttactagata ctactgatgc ggcatgataa
     1981 agagatttat tctccttaga tacaattaca gtactattac ctaacttttt gaagaaatca
     2041 cataaaaact ttgcatattt ttcatcgcct tcaattgtta taaaagattt ttttaatttt
     2101 ttgtatgaat tatatttatc tgatattgaa aacataggat ggacagaata gccataagca
     2161 ccatagtcct gtatatttga aaagatatct gaagatattg caccactgca atggcagatt
     2221 aatttgtttt tgatttgata atttttaatt tcttgccata cctcctgaat ttgaccatca
     2281 ggagtcgtaa tgaaaatagt atcattttca tctactaatt ctcttaagtt taaatattgt
     2341 ttactagatg taaaattcga agctgctaat gacgagtctt cgcttttact ataaaatcct
     2401 gttacttgta ttttatgttc ctggaaatac ttcccgaatg aacaacctac cttgccggct
     2461 ccaataaaac caacgttcat aattatcacc tccataaaga agtgagacta caagtcccat
     2521 tcttacgata tgagcttaaa aataaaaatt aaatcaaata tacagtatgt ttttttcaaa
     2581 tatcatccat agttaattta tcataatatc ccatatttta aaataaaaga tagcgtaaaa
     2641 tattttgtgt aaatagaaat ttagggtaga aaaaaaagtc cattctgtaa aattaaagtt
     2701 accacacaga aattttatag gaggactttc tcatgactaa atttactata gaaattatgc
     2761 aaacactact caataaaggg gatttagatg aattatttca ggatcattta gagcgagcga
     2821 ttaattcact tctacaagca gagctaactg cttttttaga ttacgaaaaa tatgatcgaa
     2881 atggattcaa ttcaggaaat tcccgtaacg ggaattattc acgtacattt aaaacagaat
     2941 atggcgagtt gaatttaact attcctagag atcggaatgg cgaattttct caacaaacac
     3001 taccagcata taagcgaacc aatgattcat tagaaacgac cattatccaa ttatttcaaa
     3061 aaggcattac tatggctgaa atctccaaat taattgaaaa aatgtatggt caccactata
     3121 cgccacaaac aatctccaac atgagtaaat tggtggctga agatgtttta gcttttaaag
     3181 aaagaacgtt agaagccaat tattccgtta tatttatgga tgcgacgcat atccctgtga
     3241 agcgacagac tgtttcgaag gaagcagtgt atattacgat tggtattcgt ttggatggaa
     3301 ccaaagaagt tcttgggttt actattgccc caactgagtc tgcttatatt tggaaagaag
     3361 ttcttcaaga tcttagaaaa cgtgggttag aagaagtttt attagtagtg acagacggat
     3421 taagctgtat tgaagaaagt atccatagtg tgtatccgaa tgcccaattt caacaatgtt
     3481 gtgtgcatgt atctagaaat atcgctcata aagttcgtgt tcgaggtcga aaagaaattt
     3541 gtgaggattt caaattggtt taccaagcga attcaaaaga agaggcattg gatcacatcg
     3601 actttatgac taggaaatgg aaaa
//
LOCUS       DAFLWZ010000147         3435 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000147 DAFLWZ010000000
VERSION     DAFLWZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.153"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..386
                     /locus_tag="L1V38_002855"
     CDS             <1..386
                     /locus_tag="L1V38_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317324.1"
                     /translation="IIKRLEDLEWYAYYDLLEVFASAKILDKKKREEVNKILESENSG
                     YRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYISEKENQDYNTVVREA
                     ISAVESCLIEFSGLPANKKILWELL"
     gene            741..977
                     /locus_tag="L1V38_002856"
     CDS             741..977
                     /locus_tag="L1V38_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBN1317325.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            974..1387
                     /locus_tag="L1V38_002857"
     CDS             974..1387
                     /locus_tag="L1V38_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1317326.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            1906..2856
                     /locus_tag="L1V38_002858"
     CDS             1906..2856
                     /locus_tag="L1V38_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBN1317327.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(2853..>3435)
                     /locus_tag="L1V38_002859"
     CDS             complement(2853..>3435)
                     /locus_tag="L1V38_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317328.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1256 a          475 c          614 g         1090 t
ORIGIN      
        1 atattatcaa gaggttagaa gacttggagt ggtatgctta ttatgattta ttagaggttt
       61 ttgcaagtgc taaaatcttg gataaaaaga aaagagagga agtaaataaa attctggagt
      121 cggaaaattc tggttacaga ttaagcgaaa gcaatgaatt tattccaatc acagatgata
      181 tttctattaa gtctataaat gctgtatctg aatcaccatt taattacgca aaaaatcata
      241 tccataaatc tcttacatat ataagcgaga aggaaaatca agattataat actgtagtga
      301 gagaagcaat tagtgctgtc gaaagttgtc ttatcgaatt ttcaggatta ccagctaata
      361 aaaaaatact ttgggaactg ctataaaagc aattaaagac aaatcgaata acaatgtcga
      421 tcttacattt ttaaaaccat ttgagacaat gtatggtttg gcgagtaata atggaatacg
      481 acatgcagaa aatgaaaaaa caattgtctc agatttacct gatgcagttt tggtgttaac
      541 aacatgttca gccgtaatta attatttggg agtaaaaata gcatatgact ccaataaatc
      601 atgaaaagtt aaaattcatc caagagctac attataacta ttaatttcca actctttaaa
      661 agtttagtaa ttgaaggaag taataagggt gattgaacaa tacggatata cggtgtatac
      721 ttatcgtagg agttgatgat atgaatatta aaaaacgcaa aatcagagaa gtaggtaatt
      781 caatagttgt aactttgtca aaagagagtt tattgcaaaa aggtttgaaa cctggagata
      841 ctatttttat tgatgaagat aaaatgatgg aagctattgt aaaagaggaa agcaagatag
      901 atcttgaaat tgatatgtat gttaaccaag ctttatctga gtatgatgca gctttcaagg
      961 aattagttga aaaatgatct atctaagtga aaaagatatt gtaaaattga atgttattca
     1021 aataaagaaa tattcaccgc gagaaacaat cggagtcatt gacaaaaatg cgctgagtat
     1081 ggctgtaaat caacctaaac agcatatttt tggaaaagat ctgtatcctg ataaatttag
     1141 caaagcagct gttctgctaa taaatctgat caaaaagcat ccatttcata atgctaacaa
     1201 acgtacagca tttttagccg cgtatgtttt tctcaagcta aatggctatt cactaaaaat
     1261 gaaaaatcag gaagtagtag aatttgtagt tgaaattgct acgtatcagg gtgattttga
     1321 tgacttaaaa gaggcaacaa cagatatact aaaaaagaat tcaacaaaga ccgattcaaa
     1381 aaagtagaag caaactaggg attcagttaa atctgaagat ttagtttgtt ctttatttta
     1441 gtttacataa gatacattat gcgaagttca ttattttaaa agcttaaata ataaactttt
     1501 ttataatacc aatttattta tgtaaaccaa tgaccttaat cgcttaagca agcatgttat
     1561 gtaatactct actctctcca aaactaatga ctatctattt tcaaagaagc tagaatgatt
     1621 atctgatcaa atgataattt atatttaatt cctggtctac tgctcttctt ttaatcaatt
     1681 aatgtctaac gtactgtaca cgataaagta ggaagactta ttttcaactt cggattcatt
     1741 tttttaattc ggtgaaaatc actaaattaa gagtttatcc aagttcattt tagctgagaa
     1801 tacgcttgaa aataattttg atgaattttc ctgaattaaa atttattaac ttgttgagtg
     1861 atataattgt aatgtattac caaatagtta gcacttagat tagtgatgga aaggaatagt
     1921 gagaacaaga tgactggtag aaatcccaaa gtatttatat catattcatg ggagaataag
     1981 gaaaataaag aatgggctag agaactagca gacaaattac ttgaaaacgg tattgatgca
     2041 tatatagatc agtatgattt aagtttaggt gatagattac ctcagtttat ggagcagcaa
     2101 atatccgatt cagattatgt tctaattata tgtacaccag agtataaaaa aaaggcaaat
     2161 aatcgtacaa gtggtgttgg gtatgaaggt catattatct cagcagaatt gctttctgga
     2221 aaaaatgaac gtaaatttat cccaataatt aaagaaggac gtgcaagcga agtacttcct
     2281 acttttcttg ctggaaagct tggaattgat ttatcagata gccagcatta tgatgaaaac
     2341 ttagatgatt taattacaac tatatttggt gttaagagaa aaccagcatt aggtgatata
     2401 cctaggcata ttaaaggcag tcctttacta cctatagaac ataatgaaaa taaagatatt
     2461 gaaatcttag gaattatcac tgataaagta actgtaccta aaatggatgg ctcaaggggt
     2521 tctgcattat ataaaattcc atttagatta aatagagtac caagtcagct ttggaaagag
     2581 ttgtttgtta gaaattggaa ttcaccacca cgatatacaa caatgcatag accaggaatt
     2641 gcttctgttg tagacgatga aattttactt aatggaacaa ctattgagga agtccgggaa
     2701 tatcatcggg aaactttaaa actttgcatt gaaaaaagta atactcaaga aaaaaaaata
     2761 ttgctagagg aggaacaaaa aaaagagaga gagaatgagc gagtcagatc acataaagaa
     2821 agtgttcaga aattagcaga tgaattagag ttctagttga tagtcagttc tttcttaatt
     2881 cgatacacag tttgtctagt tacattatag tctgttgcta tttttgaaat agcaacacca
     2941 ttctcctggt cctgaacgat gcttctataa acaaggcgac gttgaggatc ttttgtgttc
     3001 gcactgtata acttaggacg tcctttatag acgccgtttg ctttagcaat ctttatccct
     3061 tgtgcctggc gtcgttttga ttcagtacgc tcttgttcag caatcatggc caagatttga
     3121 atgattaggt ctttgataaa tttatccagg agaggatttc cgattgcttc agccatgatc
     3181 ggtaaattag tgataataag tcgcacattt ttcttcttta gataatttac tgaatcgata
     3241 atctcgtcat aattacgtcc aagtcgatcg atagcctcta caataaaaat atcttggtct
     3301 ctaacaaaat ctagaacttc ctgaaaaatc ggtcgatgag taatagtcgc tccagattgt
     3361 ttctcgatga aaattttttc agcaccaaat tttctcattt cctcgatttg acgttgttca
     3421 ttttgatcga tcgat
//
LOCUS       DAFLWZ010000148         3354 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000148 DAFLWZ010000000
VERSION     DAFLWZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.154"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            134..949
                     /locus_tag="L1V38_002860"
     CDS             134..949
                     /locus_tag="L1V38_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317329.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1075..1332
                     /locus_tag="L1V38_002861"
     CDS             1075..1332
                     /locus_tag="L1V38_002861"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317330.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1584..2156)
                     /locus_tag="L1V38_002862"
     CDS             complement(1584..2156)
                     /locus_tag="L1V38_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317331.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2172..2777)
                     /locus_tag="L1V38_002863"
     CDS             complement(2172..2777)
                     /locus_tag="L1V38_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBN1317332.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(3178..>3354)
                     /locus_tag="L1V38_002864"
     CDS             complement(3178..>3354)
                     /locus_tag="L1V38_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317333.1"
                     /translation="YLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMP
                     ASEAAKKDLIDILR"
BASE COUNT         1113 a          616 c          510 g         1115 t
ORIGIN      
        1 tgactagaga attaaataaa aaataattac tatctagtac gaaattaatt acataggata
       61 atatattaag gtgctggact acaagtaaaa aatactgtat gatcatgaca gattcaagaa
      121 aggagcaata agattggtta agatagcagg actttctaaa ggtggaaaaa ccgtttcaca
      181 actttataaa caaaactaca gagactggag acagttcaga aaaaacatta aggattctta
      241 ctttattcta ccaacagaac ttgaaaaata tttaccgaat aacaaagcta ttaatttata
      301 tctgtattac tgttttaagg caaagaatga aggcggggat tcctggcatt cggtcaatac
      361 catagcagag tctctaggag tgacaactaa aactataaac acctggaata aaaccttagt
      421 tgatttaggt atgattgcac gtatagacga taaccatctc agtaaatcga caattttact
      481 tcctctctct agttactata aattagccct tgatagttct ttaaaggatg ttaccgagag
      541 cactgtccat gaaattgatg gcaacttggt tgcagtttat catttgtttg aatggagaaa
      601 aaatgaggct gatgaaaatt ataacgttcc ttataacaca ctctgttgtg tttttaaaag
      661 aaaaacacaa aaagatacta tctataaatt tatcttggtc caagatgaga aaataagtaa
      721 tttcgaatta agcactcctt ctagtaagat ttatgacgat gcatatagat ttgaatgtca
      781 agatctagaa gccctccttt ccgcaaataa tctaaacaat atagaacatg aaaactttgt
      841 tgtaaacact agatttaatt tagtttctga aaaggactca gatttgttag atttgctgat
      901 agagcttact aaaaatctag ataagaaaga aaacattact gtactataac tagcatcggt
      961 ccatcattaa gtttggacta ttagaacact tgctattaca gaaaaaggta tgctagccac
     1021 gcttactatt tattggtatc aaacaagtat cttaatttga aaggaagatg atttatggct
     1081 aatttatata tagagaacaa aggagacttg aatgccatta ttactttaat cgtagttatg
     1141 gtaaaatcaa taggtaatat cacaatagga atgctgttta ttatattagc agcagtgctg
     1201 atttttatga tagttatttg gttcttaaat gaaagatcta aagacaatca acaccgtagg
     1261 gatatggaga taaaatcaat agagtcaata gattatttat cgataataac actaaaaaag
     1321 ccacgttcct aaacgtgact tacgctgaac gatatgtgtt gtttggtaga cgaacaaatc
     1381 gttcattata aatatatgat ggtatcctaa tatagtaagc gtggctagca tacctttaat
     1441 tactttacct tttacagtta ccatacacat tttttgagca gaaatcaagt aaataaaaaa
     1501 atattatatt tcacaacatg ctaatagact catatctaga acgcattaag tatttacctg
     1561 tctggttcgc tgagacttct tttttaactt tcttcaattt tcttctttat tctaaaaagc
     1621 gtactgcgac tgaaaccggt tatagcttca acttccttat acgatttacc tgaagtaagc
     1681 agttcatatg cgtgcctctt cttcggtgtg attgttgctt tcggacgtcc ttctctgaaa
     1741 ttaggattat tctttcttgc aaacattttt ccttcttggg tacgttccac aatcatatca
     1801 cgttccattt ctgctacact caacaacgtc cgtgtcacca ttcgccccat ggacgtattt
     1861 tcaatcgttc ctagattcaa aaccttgatc gttacgttat catcgagtaa aggttcaatg
     1921 atctctaatg cttctctcgt gttacgagca aatcgatcaa gcttcgtaac aactatttca
     1981 tctccaggct tcagaccagc caacagctga ttgaattttg gccgatcccg ttttgtaccc
     2041 gtaaattttt ctgaaaaaat attcttcttc tctacgccgt tctcaagcaa ctgttgaatt
     2101 tgttcttttg tactttgaga agcggttgag acacgtgcat atccatattt cgtcatttgg
     2161 tccacctact tttacaaatc atctatcgta tactcagaat acccttcata gaaatagctg
     2221 acatcgattc ctttcatata taactcgcga tcgtcaattt tatcagtcag agcattggaa
     2281 attagatagc gtatttccaa atcgtttatg ggacttcgct ccattgcaga aagatagtct
     2341 gctttatcga ttaagttcca atctacaact ttttgcaatt cttcctttaa aatgagatcc
     2401 agccaaattc tagtacttcg gccatttcct tctcgaaatg ggtgagcgat attcatctcc
     2461 acatatttct tgataatctc ttcaaaagaa gtttgtggca tctgatcaat atgctgtaac
     2521 gaatgttcta aatacataac tggtgcaaat cgaaaatttc cttttgcaat attgaccgat
     2581 cggatttttc cggcaaaatc gtaaatatcc gaaaatagaa attcatgaat ttcagataaa
     2641 cctttaaatg taccaacttc gatttcattt atttttccac aatcgtacaa ttctttcgct
     2701 ttttgtttac tgagtttttc ttcaacctta gccaactcaa cttgattggt taatcccaat
     2761 ttattctcta aaatcatgcg aaatctcctt aactttatga cataagttta tgaaacactc
     2821 tcaaccccat tatatcgcga ttttgtttat gtgtcaaaaa ctattaagtt tctgaccccc
     2881 gatagatttt tcaagtgtct ctattttgca cagtctagtt gacctttgat acacctctat
     2941 atttatagag aatctaaaac atcaacatgg catactcaaa attctaaata ttagggataa
     3001 agaattctcc tatacaatca aaaatttcct ttatttcgaa ctccggtcac ctaactctat
     3061 tgatctctta caagccaaag aatatctcta tactacaaag aaacaatagg gtgcctggtt
     3121 ggtctctttg tgttttattt tagaatctag aacgtaaata ttcttgtcat tctgatttta
     3181 tctaagaata tcaattaaat ctttttttgc agcctctgaa gcgggcatta cagaaaagac
     3241 cagtccaata accgaagata ccccaaccgc tagtaaaata gtaaatagat caagtgacac
     3301 gtttaccttt atcaaagaac caacactata agcaagagcc attcctaata aata
//
LOCUS       DAFLWZ010000149         3295 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000149 DAFLWZ010000000
VERSION     DAFLWZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.155"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            40..591
                     /locus_tag="L1V38_002865"
     CDS             40..591
                     /locus_tag="L1V38_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBN1317334.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1267..1521
                     /locus_tag="L1V38_002866"
                     /pseudo
     CDS             1267..1521
                     /locus_tag="L1V38_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1591..2103
                     /locus_tag="L1V38_002867"
     CDS             1591..2103
                     /locus_tag="L1V38_002867"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317335.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2100..3137
                     /locus_tag="L1V38_002868"
     CDS             2100..3137
                     /locus_tag="L1V38_002868"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1317336.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1215 a          555 c          654 g          871 t
ORIGIN      
        1 aagagcgagc aagacaggaa cgagagaaca aacatactca tgaaaagact agaggcttcg
       61 acctcgaact ttaataataa gttagatgtt tttgaagaaa agactaagca tgcaagatta
      121 aactttgaaa caactgcaaa gcactatatt aaacgacttg atgaagataa tttgaaatta
      181 gattttcaac aagctattca agatgaatta agcgatacta aagacgaaat acgtgaagtg
      241 acgaaacaag cgagagaaga aacaaaagag tataaagaaa tcttagaaag taaaataaaa
      301 gaccataaca aagtggttga taaatcgaat acagcgctaa aagtgatgac aaaaggcgtt
      361 acaaatatat tttttgtgct aattattttt gtacttgtaa tgcttgtgac aggtccgata
      421 ggtcatttct ttggtattga acatttatat agctttatta atggttttat tgatgaccac
      481 gaaagtgcat ggcgatattt gatgttgata ctttatgcag taccctatgt attcttcgct
      541 atcattctgt ggctcatagc attgtttttt agagtattta atgaccttta ggtagattta
      601 tatataaaaa gggctaaata cgcaaaatac ccccttaaaa tgcaaaataa atgcaaataa
      661 gggggtaact ccttatgaaa aaacaactaa tagtattata acacgttttt atgccgagaa
      721 aacttattgg ttggaatggg ctatgtgtta gctaacttgt tagcgagttg gttggacttg
      781 aattgggatt aatcccaaga aagtaccaac tcaacaacac ataaagccct gtaggttccg
      841 accaataagg aaattggaat aaagcaacga aaggagttga gtaaaatgag tgagaaaacg
      901 aagaaaatca ttcgagtatc attagctttt tcacaagtag tagtgcaatc attgatagtt
      961 tattatactt accagcaata taaattatct aaagagaatt aagttttgat tatgtaataa
     1021 gttttggtac taaaaaagac ttgatctaat tagaccaagt cttttgttag tgttatatta
     1081 ataacaaaat aaaaataaga agtcgctcac tccccgacca aagtttgtga gcaaaataaa
     1141 cagtcgatgt ttgtttctta attgtatatc ttgatattaa acgatttaag attattcttc
     1201 aagatatata ttcgcaaatg taattggaaa agcgacttct taaacaaaat taaggagtcg
     1261 ctttttatgg caaaaataac gaaaaatgag caagaaaatt tggtggaaaa ttacacaaaa
     1321 aaaccggcgt actctaatag ccggttagac gcacatttcg tgtgcacttc taatccgaaa
     1381 ttgagctttg acgctatgac gatagtcgga aaccttaata aaaacagcgc taaaaagcta
     1441 tccgatttta tgagtttaga tccacaaatt agactttggg atatacttca aacaaaattt
     1501 aaagctaaag cactacaaga ccccctatgt taggctagtt gtcgtatagg ataataagtt
     1561 ataataaaga ctatacggag gatgattacc atgacaaata aaaacaatga acgttactct
     1621 accgaactga aagcgacagc catcaagaaa atgatgccac ccgaaaatag ggggattcgc
     1681 caattaagtc aaactttggg cattccagaa gcgactcttt gttcttggcg taaaaaagct
     1741 agaattcaag ggaatactac acccggaacg aaaaaaaatg tcgaaaaatg gtcaagtgaa
     1801 gataaatttt taattgtgat ggaatcattc tcaatgaacc aagtagaact tgcggaatat
     1861 tgccgaaaga agggcttatt taaagaacaa attgaggctt ggaagaaaac gtgcttatct
     1921 gcgaatgaac aggaagaaaa tcgaacgaga gaacttgcaa ctgaactaaa agaagagaaa
     1981 aaacaagcgc gtcaattaga gaaagaatta cgtcataagg aaaaagcatt agcggaagcc
     2041 gctgctctct tattactaag aaaaaaagca cacgcgattt ggggggacca agaggaagaa
     2101 tgatttcatc ttcagatcgc aaacaagctg ttgaacttat tcaagaagcc aatcgcaatg
     2161 gggcccgtct cacctatgcc tgtaatgagc tgaatattag cgttcgaacc tacgaacgat
     2221 ggacgcgtga aggtacgata gcgcatgatc aacgcccttt ggcgaaacgt cctgtaccca
     2281 aaaataaact gacggatcaa gaacgcgaaa aaataataga aaccgtttca aaaaaagaat
     2341 ttatgaattt gccacctagc caaattgtac caaaacttgc ggattgctcg atttatattg
     2401 catcagagtc tagcttctat cgtgtattgc gagaaaaaaa tatgcaacat caccgtggcc
     2461 gaagtcaagt ttcacaaaaa cgcataccgc caagtcacct tgcgacgaag ccaaatgaag
     2521 tttggacttg ggatattact tggctaaaag gtccaataaa aggactcttt taccggttat
     2581 atctcatcat tgatttattt agccgtaaaa tggtaggctg ggagatttgg gaatcagaag
     2641 aagctcgtca tgccgaaaaa cttattaaac agacggtgct taaggaacgt atccaaggac
     2701 agccgttggt tttacactcc gataatggca gccctatgaa agccgcgact tttcaagtct
     2761 tactcgaaaa attaggaatt caaagttctt attcaagacc acgagtgagt aatgacaatc
     2821 cttattcgga agcggctttc cgaacgttaa aatatcgacc agaatatccc aataacggct
     2881 ttaaaacaat agatgatgct cgaaaatgga cgaaagagtt tgtcgattgg tataacgatt
     2941 ctcatttgca tagtgggatt caatttgtgt ctcctgcagc gtgtcatgaa ggacgacatc
     3001 tcgctatttt agagaaacga aagcaggttt acgaggacgc taaaaagcgc catcctgaac
     3061 gctggtcaaa aggtgttcga aattggactc cacatcaatc ggtggcgttg aatcctttaa
     3121 aagaaacaga aagttaacag gagcataatc tttcaagatt atcaaataac cctcgtcacc
     3181 caatagggga aaaagttatt cttcccctat tggataacga ggccaaccga ccatagggag
     3241 gttctgcttt ttgataggtg gaaaataaaa atacgacaac tatattgaca aacac
//
LOCUS       DAFLWZ010000150         3217 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000150 DAFLWZ010000000
VERSION     DAFLWZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.156"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..159)
                     /locus_tag="L1V38_002869"
     CDS             complement(<1..159)
                     /locus_tag="L1V38_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBN1317337.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHW"
     gene            317..580
                     /locus_tag="L1V38_002870"
     CDS             317..580
                     /locus_tag="L1V38_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317338.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            604..792
                     /locus_tag="L1V38_002871"
     CDS             604..792
                     /locus_tag="L1V38_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317339.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(875..1060)
                     /locus_tag="L1V38_002872"
     CDS             complement(875..1060)
                     /locus_tag="L1V38_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317340.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            1275..1646
                     /locus_tag="L1V38_002873"
     CDS             1275..1646
                     /locus_tag="L1V38_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1317341.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(1796..1868)
                     /locus_tag="L1V38_002874"
     tRNA            complement(1796..1868)
                     /locus_tag="L1V38_002874"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1833..1835),aa:Gln,seq:ctg)
     gene            complement(1914..2342)
                     /locus_tag="L1V38_002875"
     CDS             complement(1914..2342)
                     /locus_tag="L1V38_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317342.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(2402..3160)
                     /locus_tag="L1V38_002876"
     CDS             complement(2402..3160)
                     /locus_tag="L1V38_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1317343.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1066 a          517 c          605 g         1029 t
ORIGIN      
        1 ccaatgccta aaagaaaaaa tttgataagt aaaatataca gcaggtaaag aggccagtaa
       61 aactgaaaac ttcttttttg tccattttat gtaatagaaa agaatgctta tcataataaa
      121 aaaaggaata taaaaaacaa attgaccgat cgcgatcata ctattgcctc cgataaataa
      181 agtccatgat acaaaataac actttgtgcg aaatggcgca agcagttttg tggatttatc
      241 cggtaaaatc tgtatcgatt ttgaaattag aggagaaact tgctataatc aaagtgaaag
      301 aaggagtggg attttcatgg atcatgtagt gttagaaatc gatttgcatt tgatcaataa
      361 tattcgggtg atttactatg ttgtaagtaa cagtgtcgaa caacgtgtac tgacgaataa
      421 aataaatggt attttagcaa agaaagacgt tcaccgattc aataatggtg aaggaagtta
      481 ttatagtatc ccagtagaaa aaattattta tacgacagtc aaagtcagag aagatctaga
      541 taccaaaaaa gcatatgaac ctatttttac aacttattga ttgacagcag atggaggaaa
      601 aaaatgaatc catatgaaca acttattcaa gatttgatcg atggaaaaat cgaaaagatt
      661 gatgtaaaaa gagaagaatt aatggctttt cgagaagcgt ggctgaagtt ggagaatcgt
      721 aaatatgtgg tgggaaaagc ctcactgaac ggcaatgtga cttatcatta cgatccgaca
      781 cgtttatttt agtatgaagt attcagaaaa gaaccaaagg aggacgatgc agcagcattg
      841 tcctcctttg attttacaaa agtgaaagtt ttacttattt gaatagattt ttaaatttgt
      901 ttttgacact gtcgatattt acatctttta aaagattttg ggctttctct ttataaggtc
      961 ctaattgttc tttatgttct tcgataaatc gttttgcgcc atcgaaattg ccgttcttaa
     1021 tcatttcctt gactttttga aataattctt cttgattcat tttgaacaca tcctttgcta
     1081 tcaacatgat tttttacatg gacaaaacga gaaaaactga tttatccaca cgtcaataat
     1141 atcaaataac gatcattttt actaaaaaaa cactcgattc tcgcttctaa agtaggagaa
     1201 aaatctccaa cttgggacgg atggaatttc tttaactgac ccatatactg aatatataac
     1261 aaggaggtag aaagatgaaa gtgattaaat atttgattgg actggcggcg attagtggta
     1321 ttttgctatt tggactgaaa tattatactg aaggaagtta tggagaaatc cctggtatac
     1381 ttgatcagct aaatccatta gttgaaaaag gagaggtcta tgtaaagaca caaaaaccag
     1441 aggaagtaaa tgaatatggt acagcaaggt atgtgcagaa agctgctgat gccaatggga
     1501 aagaacgaac ggttgaattt aatggtcttt ctgtgttaaa agaaaatcat tatttgaaaa
     1561 ttagcaataa aggagcacac atagaaacgt atgaggaagt tcctagagaa aaagttccgg
     1621 agaaagcatt agcaattatt gggtaaatca gtttttgtat taagaatacg cccgatttta
     1681 ttattcataa tttaattatg taaactaaat acaagtagta aaaataatac aataatcccc
     1741 ctgcaaaaag attgttcttt tacagggggt tcattttttc agcaagcaca tcaaattggg
     1801 atggcagggt tcgaacctac aattgcttga ttcagagtca agtgccttac cagtttggct
     1861 acatcccatt tattcaacaa aataatcata gcactttcct aaaaaaacgc aagttatttt
     1921 tcttgatcgg atagttgttg ctttactcgt aaaaggcggc gtactagttt cttttctaat
     1981 ccagcaggaa gggcaatcag ttctgctact gacaagacgg tgtccaataa ctgatattct
     2041 ttgacaggtt cattcataat atgatagatg tttgctaaac gttcaatata ttcaaagcga
     2101 gtatactctg ttcgagcaat tagaaatttc aataaatcgg tggctttctc gtactcttga
     2161 tctgcgtaat aaacaagaga ttgacgatac aatttgattt ccagttcatt gagggtagca
     2221 ggtctgcgac gctcgttcca ctcattaata gagactttac cttgaacatt tcccttgcag
     2281 tcacggacaa aaataatcgg aatttcattt ggatccattt ttttatgtgt gaatttttcc
     2341 attatctacg ctcccttcaa aggtttggta tcttgagtat aagggatttt tgtttgaatt
     2401 actagctttt ctccaaagtt agcatctgtc cacccattgc agtgaaaatc gccgaaaaat
     2461 cgttgatcgg tactgctcga ttttttacac catagggatc gttgacataa atattttctt
     2521 tgtcatatcc agtgactaca caagcatgaa caagaggagt gactcttact tctccattat
     2581 ttgtggtcca agtcataaaa tcagtttcat ctgggacttc aaaattgata gtcacagaag
     2641 tccagacagg atttccttta gatagtgctt ttttgatatc atcgagttga gcatcggttt
     2701 ttggaaaagt gtgataatcc gtttggacga tttgctgagc aagggaggca actgggggaa
     2761 catagacgac catagcccag tctccgccac tgatatcacc aacaaatcct tcattaggat
     2821 cgccatgagt cccatctgca ttgaaaacag ggacgtaatc caattgctca gctaactggt
     2881 ttttagttgt ttcataacca taaaaagata aaagcataga aagcgaagtg acttcacagc
     2941 cattttctaa agaaggagaa tcaaactggc tctctaatgg aacatctagt aaaacttctg
     3001 ctttctcttt tgtctttttc gttttttgtg ttgaactttt ttgtgcagtg ttcattgtat
     3061 gttctggaga atggatatgt aggtaataac ttgtaccgct taataaaaga gcagctgtgc
     3121 cccctagaaa caatagtttt ttgaacgttt ttttcttcat ttgaaatctc ccttttcagc
     3181 tgtttatctt tcctattata aatgtatttt tattgga
//
LOCUS       DAFLWZ010000151         3211 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000151 DAFLWZ010000000
VERSION     DAFLWZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.157"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            553..1725
                     /locus_tag="L1V38_002877"
                     /pseudo
     CDS             553..1725
                     /locus_tag="L1V38_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
     gene            complement(1855..>3211)
                     /locus_tag="L1V38_002878"
                     /note="aph(2'')-Ia"
     CDS             complement(1855..>3211)
                     /locus_tag="L1V38_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBN1317344.1"
                     /translation="TVRDFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGY
                     GQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNA
                     NAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKA
                     MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKDYAKEKAIYNF
                     LNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIAS
                     FLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATT
                     VFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTN
                     FGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYK
                     D"
BASE COUNT         1106 a          572 c          415 g         1118 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttatat agataaagtc cgtataattg tgtaaaagta
      481 aaaaggccat ataacagtcc ttttacggta caatgttttt aacgacaaaa acatacccag
      541 gaggactttt acatgaccca agtacatttt acactgaaaa gcgaagagat tcaaagcatt
      601 attgaatatt ctgtaaagga tgacgtttct aaaaatattt taacaacggt atttaatcaa
      661 ctaatggaaa atcaacgaac agaatatatt caagcaaaag aatatgaacg aacagaaaac
      721 cgacaaagtc aacgaaatgg ctattatgag cgcagcttta cgacacgtgt aggcacgcta
      781 gaattaaaag tacccagaac acgtgatggc catttttcac ccacagtgtt tgaacgttat
      841 caacgaaact aaaaagccct catggcttca atgttggaaa tgtatgtatc aggcgtttca
      901 actcgtaaag tatcaaaaat tgtggaagaa ctttgtggta aatccgtctc taagtccttc
      961 gtttctagct taacagaaca gctagaacct atggttaacg agtggcagaa tcgtttatta
     1021 tcagaaaaaa attatcctta cttaatgacc gatgtactct atataaaagt acgagaagaa
     1081 aatcgagtac tctcaaaaag ctgtcatata gcgattggaa taaccaaaga tggcgaccgt
     1141 gaaattatcg gcttcatgat tcaaagtggc gaaagcgaag agacctggac aacatttttt
     1201 gaatacctaa aagaacgcgg tttacaaggt acggaactcg ttatttctga tgcgcacaaa
     1261 ggattagtct ctgccattag aaaatccttc accaacgtaa gttggcaaag atgccaagtt
     1321 cacttcctaa gaaatatctt taccaccatt cctaaaaaaa attcaaaatc tttcagagaa
     1381 gctgttaaag gaatttttaa gttcacagat attaacttag cgcgtgaggc taaaaatcga
     1441 ttgattcatg attatatcga tcaaccaaaa tattcaaaag cttgcgcatc attggatgat
     1501 ggattcgaag acgcctttca atataccgta caaggaaatt cccacaatcg actaaagagt
     1561 accaatctaa ttgaacgact gaatcaagaa gtacgcagaa gagaaaagat tattcgcatc
     1621 ttccccaatc aaacatcagc caatcgctta attggagccg ttcttatgga cctacatgat
     1681 gaatggattt attcttcaag aaaatacatc aattttgata agtagaaatg gtaaaaacat
     1741 tgtatagcat tttacacagg agtctggact tgactcactt cctttattat ttttcatttt
     1801 tttaaactat ttaatactaa tgtcttttat aatagctttt catatattat ataatcaatc
     1861 tttataagtc cttttataaa tttcttttct accattttcg ataaattcct gtttaatatt
     1921 tttaattcca taaacaatag tttcaatagg ataatattct tcaactatat cttgatattc
     1981 ttttgctttc tcaatatcta tatttccata cattcttaat atatcttctc caaaatttgt
     2041 tcctatttct tcttcactat cttcaagtaa gtatataaaa tcacaatatt catctataat
     2101 tccagaatct ccaaaatcaa ttattccagt taatctatta ttgccatcta acaatagatg
     2161 attacaacta aaatcattat ggcataaaca ctttttaccc tcaaaaactg ttgttgcatt
     2221 tagtctttcc ataaaacttt ctatataatc tttttctata tcagttaaat cattataaat
     2281 agtttcacgc aacaatatat actcttctaa tacattttgt ttattatcaa tagtacattc
     2341 actaatatct gtataatcta aaccgtgcat ttgtcttaaa aaactggcaa tatctcgttt
     2401 taacaaattt tgttcttctt ctgacatagt agaataaatt tctggtgtta aaaaagttcc
     2461 tttaatttct ttataaccta gtatagataa ttcatcacta atatacgaat attcaatatt
     2521 aggaattttt acattagttt ctaaatttgt atttaaaaaa ttatatattg ctttttcttt
     2581 tgcataatct tttttcttat tagtactaaa ttttgtttta aaaatgtatt cattattaac
     2641 taaatatgcc acactatcat aaccactacc gattatttca atactatcta ctttgaaatt
     2701 atcaaagtaa tgctcaatta aatatttcat tgccttaaca tttgtggcat tatcatcata
     2761 tctatattcc attaaataac aatcttcttt tttgccctcg tgtaattcat gttctggcaa
     2821 atcttcaata attctaaaac cagatttttg gtatgccctt attgctcttg gattattttt
     2881 atgagggtct aaaataactg cattagcatt tctttctttt ttcaaaaatt caaaaatcaa
     2941 tttaatatat cttgtaccaa ttcctttact ccaataattt ggctctccta taaattgatc
     3001 cataccatag actatctcat cagtttttgg ataatgataa tcagtatata actcatcata
     3061 cattttatat atttgtccat atccaatagg aacattgtta tattcaataa ttactctaaa
     3121 aacttcatct tcccaaggct ctgtataatg tttttttaat gattcggttc tgttgcaaag
     3181 ttttaaataa agaataaaat cccttacggt a
//
LOCUS       DAFLWZ010000152         3153 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000152 DAFLWZ010000000
VERSION     DAFLWZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.160"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            239..838
                     /locus_tag="L1V38_002879"
     CDS             239..838
                     /locus_tag="L1V38_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317345.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            887..1603
                     /locus_tag="L1V38_002880"
     CDS             887..1603
                     /locus_tag="L1V38_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBN1317346.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            1617..2396
                     /locus_tag="L1V38_002881"
     CDS             1617..2396
                     /locus_tag="L1V38_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBN1317347.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            2479..2835
                     /locus_tag="L1V38_002882"
     CDS             2479..2835
                     /locus_tag="L1V38_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1317348.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            2825..3091
                     /locus_tag="L1V38_002883"
     CDS             2825..3091
                     /locus_tag="L1V38_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317349.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
BASE COUNT         1159 a          464 c          628 g          902 t
ORIGIN      
        1 tactgacaaa ttttttaaag gggcaatatt aatgttctga gataatcaaa tcttaccgaa
       61 aatatcaaaa gtccaatgtg acacaattgg attttgtcac attcgttaaa atcgctccat
      121 ccttagaggc tctaatagga aatcactttt cttttagcgc cttttttcta tagcttgttt
      181 aaatgtgact tattatctgt tataatcgta ttaagtaaca tttgagaggt gtctaaaaat
      241 gaaaagcgtg gaaccgattc gcgacaaaaa aaagatcgat gccatgaagg ccattttggc
      301 ttccggaaaa tatgggcaac gaaatttggt gcttttttcg atcgggatca atacagccta
      361 tcgaatctcc gatttaagac agttaaaatt aagggatgtg ctagaaattt cccgtgggcg
      421 ggtgatcgtc aaagaacgtc tggccatgaa ggaacaaaaa acggccaaac acaattcggt
      481 cttcatttcg aacaaattgc gaaaagtgat tcttgattat gttcaatccg aatttcctga
      541 gcagttgcaa gcacaagact tcagcaagta tttgtttcca agtcgaaaag gagcagatac
      601 gcctttgacc cgacaaagcc tttggcggat cattcatgaa gcaggaactg cagttgggtt
      661 aaaagaaatt ggtccccatt cgatgcgtaa gacctttggc tattttttat acaagcaagg
      721 aaccaaaaca gagatcattc agtcgctgct aaaccattct tcacaacggg agaccttacg
      781 ctatattgga atcacccagg aagacaaaga tactgcagta aagagtttgg atttatgaca
      841 gaataatgcc ctatataata gaaggaaaaa ttcaagaggt gagaaaatga acgaagaaaa
      901 gcagcctaac tttcctgata aatatcactt atctcgcaaa gagtctgtgt atttattgaa
      961 gaaaaacatt gtagaactgg tgtataatgc ggggaaattt gaagggttaa atacaacgtt
     1021 gttacaaaca gaagggatta ttaagtataa tcgggccaac aacgtggctg tagatgatgt
     1081 cctgaccgtc gttaacttaa aaagaggctt tgaaatgctt ttaaatgacg tacaggagcc
     1141 cctgttagag acaagtaagc ggattaatcg gatcgttgca gcagaggatg cgctttttcc
     1201 cggtgaaata cgaaccggtg gggtagaatt atcgacgatt caaggaagat atgtgccacc
     1261 aatgttaact gaagacgagg taaacaatca atatggtgag ataatgaatc aagagatatc
     1321 agatacggaa aaagccctgc gactgtttct attcatttcg aaaaatcaaa tattctggaa
     1381 tggtaatgtg ggtacagcct tgttgattgc gaataagatt atgtttagca acggtttagg
     1441 actattatca atacccgaaa atgtatttat gaaatttaac gaacttttat caaagtattg
     1501 caacagtaat ctattagtca atgagtcaaa tattatatca tttttatatg aacagtgtat
     1561 ctttggtatt aattatttga aaataatcca acatacaatt taagaggtat aagtaaatga
     1621 tgactataga cgaagcaaaa caattagcaa cttatttttc agttggttca gcgggatata
     1681 ttttagactt tactaatgta acgtggaaca tatttacaaa gaaaatcgta gggattgaaa
     1741 tacaaaatca ttatgggggc tcaaagggag tatcctttca aaagtttctg cttgacgatc
     1801 aatttgatga ttcgttaaag aatcggttaa tccaatcttt aaaaggtatt atggatcgag
     1861 ataaaaaata tgaatctact gaaatgaatc ccatagttca gttgcttttt gaggaagtat
     1921 ttaaagaaga tacttcaact gcattaagaa aaatgaaatt ttcaagcgag attgatttac
     1981 tttatattcg gcagctaccc attaggattc aaacagatat taaaaacaag gattttgact
     2041 ctgttttgac aaaagcaaat actttaatag atgaagttct aaaatttatt attgaaaata
     2101 ccgaaggacc gagtgttaat attaatttat ttaagtcaaa agaattaaga aaagaagtat
     2161 ttggccgcct caatattaaa actgaaaaag atatggataa tagaatcaaa gcccttgttg
     2221 gagcactcaa tacattatca gataaaatac tcgaaatgag aaatagtcaa ggagatgctc
     2281 atgcacatgg ctcaaataga atagtaatta aggaagaaga agcaattctt gttgcaaatt
     2341 cttctatggt tttgtgcgag tatgtgttta ctaagtataa aggattaaat agataataaa
     2401 atgcatattt tatagtatac aattcgaatt tttatgttat atactataat ataaaatcaa
     2461 tatatgatat aattgggtat ggaaaaaata tcttttgaaa catttaaaag acccaatggt
     2521 catgatgaat ttttagaatg gttggaaaca ttaccaaaaa aagatagtgc gaagctttta
     2581 cgtacaatag aagaaacaga aaagaatggg atgctagtag ctcaacggtt gaaatgggtg
     2641 aaaaaattag acactaattt gtacgaatta agaagtaagg taggatcaaa catccaaaga
     2701 gccatctatt tccatgtgga caatggaagg tatgtcatta ctcacggatt tactaaaaaa
     2761 acggagaaaa caccaataac tgaactcaag catgcaaaag aacttagaga ggagtggttc
     2821 acaaatgatg attaaaaaat tgattgaaga aaagaaaaaa gataaagatt ttgcagaagc
     2881 atatgaccgt gaaggaagaa aactcgaaac tgcggttgct ctttatcatg ctcgggagga
     2941 agcagggcta actcaagcgg agcttgcaca aaaagcacat acaactcaat ctactattgc
     3001 tcgaattgag agaggggata acgtatcttt cgataaactt gatgatatcg ccagggcatt
     3061 aggtaaaaag ctggtagtag aatttgctta aaagcgagtt gaaaatatat ctataatagg
     3121 ctcctaacta atcaattagt ttagtgggcc ttt
//
LOCUS       DAFLWZ010000153         3108 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000153 DAFLWZ010000000
VERSION     DAFLWZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.161"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..712
                     /locus_tag="L1V38_002884"
     CDS             <1..712
                     /locus_tag="L1V38_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1317350.1"
                     /translation="ANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTL
                     DTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDD
                     KPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNT
                     GKELARVKADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTK
                     GGAQDFHDKRWYLNIPQR"
     gene            969..1616
                     /locus_tag="L1V38_002885"
     CDS             969..1616
                     /locus_tag="L1V38_002885"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1317351.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            1899..1972
                     /locus_tag="L1V38_002886"
     tRNA            1899..1972
                     /locus_tag="L1V38_002886"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1933..1935,aa:Ile,seq:cat)
     gene            2518..3084
                     /locus_tag="L1V38_002887"
                     /pseudo
     CDS             2518..3084
                     /locus_tag="L1V38_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
BASE COUNT         1108 a          471 c          580 g          949 t
ORIGIN      
        1 tgctaatgca aatagtcctg tgcagattga gttacaacac acacatgata aagcaacgtt
       61 tgagaaaaac tacaaggcat acgttgaatt agctagagat tcagcaatga aatatggtat
      121 tccacttaca ctagacacac cgtataatca accagggatc aaatcgcatt tatgggtaac
      181 acaaaatatt tggggcgatc atacagatcc ttacggttat ctttctgaaa tgggcgtaag
      241 taaagaaaaa ttagcctatg atttggctca tggatttacc gatgaaaatc cgacaacttc
      301 agatgataaa ccagtcattg atccaactcg agcaggtgct gcaaatccta ccctgacaga
      361 tggaacaaat tacgcccaca ttgatcagtt cggagaaatc gaaaacgcaa acttacatgt
      421 ggctggttgg cacatcgcta actataaata cgagtatatc ttcattatgg attacaatac
      481 tgggaaagaa ttagctcgag taaaagctga tggaatatat agaccagatg taaatcaagc
      541 ttataatact ttaggaaatg ttggctatca tgtatctttt aacatgcgca acttccctaa
      601 taagaaagtc tatgtaatga tgcgggcaac gaatgatcca gaagggaaca ctaaaggcgg
      661 agcacaagat tttcatgata aacgctggta tttaaatatt ccgcaacgat aaaaatagcc
      721 cctcgttttt gaggggaagt acataatgca aatttgtcca taacttattg attatcttgt
      781 aaaaatgcgg taatttaata gttagtgaga agaggtgctt aattatagtt aaaaaagagg
      841 aaatagaagc agcatgtaac caagcaaatg ttaggtttat tggagaagct ttatctggat
      901 atcctaagta taaatactta cacaactggt tacaaagtaa aagtttttat cttaataaag
      961 aaagatgcat gcctaataaa aattataggg tttataaaag aggaactatt gtatatgttg
     1021 attttggggt gaacgtgggt tatgagttat ctggtaatca ttttgctatt gttttaaata
     1081 ataaagataa ttcgaaaaat ggtgttgtat gtgtagtacc aatctcttca aaaaagaaaa
     1141 gtaattatgt atctgtagga aaaatattag aagttgctag tattaaacaa tttataagcc
     1201 aagctgataa attaaaagag aaacttagga taattatttt actttcatta aatagaggca
     1261 tcattgatga aagcgatttg aatagtttta ttaaagatat tgaagctaaa ggtgaaaagc
     1321 tttcagtgga agaagtagaa aaacgagctg taaaacataa tttggtttgc gagacaaggg
     1381 aacaagtaat taaagaaata aaatcattat ctgaagatat ggtaaaatat cagaaggtgt
     1441 ttaattgcta caagaaatat acacaagaat cctatgtaat gccacttaat atccaaacga
     1501 ttagtaaaaa tagaattaga agaattaaca agtttgatcc ttctggaaat atgaaggcac
     1561 ctggaaatgt cctcaatgaa gtagatgaaa gtttaaaaaa atattttaca aagtaaacga
     1621 tatttttgtt gacatttttc tgttcgttag ttaccatgta gttatagaag gacgtaagcg
     1681 cctattttta atgtacacat cgggacgtat gcgcccacat agaaacatag ttgagagaca
     1741 tctatatggt gtctcttttt ttattaatat gcaaaaaagt ctagtttttt caataatatt
     1801 tatgtaataa taaattagcc accacaacaa agaatgaaac ccattattat ctagtctatg
     1861 tccattcttt ttgtttgcag tagttgtgat ggctttccgt actcttagct cagttggtta
     1921 gagcagacgg ctcataaccg tccggtcgta ggctcgagtc ctacagggta catactctaa
     1981 gtgatttaaa ttgcgaataa aatataaaaa tgactcccct tttgactccc ccaagcagta
     2041 tatggatgtc tctaaaagtt gtttttttag ataataaaaa gctgataata agcgaaaaac
     2101 acttaaaatc agctttaaac cctattctcg aaatccggcg aaccggctaa taccggcgcg
     2161 caggttcaaa tcctgtacct tccttatatc aacgattaga ggttgtgaag aagctgtcct
     2221 gcatcaagta ataagaacgg ccaaacaaaa atagcttttc ctattttttc gtttgattgg
     2281 gcttattacc gcagatgcaa gcttttgaac accgtttgtt cggaataagg ggctgtgaca
     2341 agacttttgt cacagcccct tattgttgta cttttaacct acaatatttt ttgattcccc
     2401 ctgagtacta ttttttataa atgctagtaa atcaatcttc tttggccttt ttttgataaa
     2461 aaaaatacta gatgtaagat aaaagtgtaa aaacgatttg ttttaggagg ggaaacgatg
     2521 tgtaccgcaa tcacttatgc aacgaaagac cattattttg gaaggaattt tgattatgag
     2581 atgtcttata atgaagtggt cactattact ccaagaaatt atcgtttcga ttttagaaag
     2641 gtaaaaaatt tagataaaca ttatgcaatg ataggaatag cagctggggt atccaactat
     2701 ccactctatt atgaggctac aaatgaaaaa gggttgagta tggcaggact gaattttcct
     2761 ggcaatgctg attataaaga attacaagaa ggaaaagata acgttgcacc atttgagttt
     2821 attccatgga tactagggca atgctcaacc atagacgaag ctaaagaatt attggctact
     2881 atcaatctag tcaatatcga ttttagtgaa aaactaccct tgtcaccttt acactggtta
     2941 ttagctgata aagaaaaatc gatagtaatt gaaagtatga aagatggact tcatttatat
     3001 gataatcctg tcggtgtgtt gacaaataat ccgccatttg attatcaatt atttaatctg
     3061 aacaattatc gctcgctatc aaatggaacg agagtataaa atattttg
//
LOCUS       DAFLWZ010000154         3088 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000154 DAFLWZ010000000
VERSION     DAFLWZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.162"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            58..813
                     /gene="fabI"
                     /locus_tag="L1V38_002888"
     CDS             58..813
                     /gene="fabI"
                     /locus_tag="L1V38_002888"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBN1317352.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(923..1936)
                     /locus_tag="L1V38_002889"
     CDS             complement(923..1936)
                     /locus_tag="L1V38_002889"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBN1317353.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            2101..3021
                     /locus_tag="L1V38_002890"
     CDS             2101..3021
                     /locus_tag="L1V38_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBN1317354.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT          897 a          623 c          589 g          979 t
ORIGIN      
        1 ttattctcta tttttttacg actatcaaat ttttatcaga aacaaaggag agtcattatg
       61 tcatttctag aaggaaaaaa aatcgtcatt atgggcgtcg ctaacaaaaa aagcattgct
      121 tggggttgtg ctgaagcaat gttgaaacaa ggggcagaaa ttatctatac ttaccaaaat
      181 gaacgaatga aaaaatcatt agtcaaattg gtcggcgaag aagcattcac tgtagaatgt
      241 gatgtttcta gcgacgaaag catcgaaaaa gcaatgaatg ccatcggtga atatgctggg
      301 gagatccacg gccttgtcca tgcagttgct tacgccaaca aagaagaatt gtccggaaat
      361 gtgtctgata tttccagaga cggctatcaa ttagctcaag atatcagcag ctactcttta
      421 attgctgtat caaaatacgc acaaccgttt cttgcaccaa acagcgggat cgttagcatg
      481 acttatctag gttcagaacg cgcaatcccg aattataaca tgatgggtat tgcgaaagct
      541 tctcttgaag ctgctatccg ttatttggca gctgagttct cgcctaaagg aattcgggtc
      601 aatggaatct cagctggggc aatcaaaaca ttagctgtca caggtgttaa agactatcaa
      661 aaactgatcc agttatctga atctcgtacg cctgatcagc aaggtgtgac gatcgaagaa
      721 gtcggtaatg cttgtgcttt cttaatcagc ccactttcca gcggaatcat cggtgatatt
      781 atctacgttg acaaaggtgt ccatctttca taaacttttg ttgcattctt taaagtaaaa
      841 catataaaaa tcaggaaaaa actttttaaa gtctcttcct gattttttct ttttacgttt
      901 ttttcaactc attactttga aattattcca cgacttcaat ccagccttct ggtgcttcta
      961 tgtctccaaa ttgaatacct gtcaattcat catacaaccg ttttgttact ggtcctactt
     1021 ccgtttcact ataaaataca tgaagattgt tattgtgata aatcccaccg attggagaaa
     1081 taacagccgc tgtaccacat gcaccagctt ctgcaaattg atctagatca tcaatgaaaa
     1141 tatctccttc aattgcttgc agtcctagtc gttcttcagc taactgcaac aaggaatatt
     1201 tcgtgatact tggtaagata gagggcgatt gcggagtgat gaattttccg tcttttgtaa
     1261 ttccaaagaa atttgctgca cctacttctt cgattttcgt atgtgtggct ggatcaagat
     1321 aaacacaatc tgagtaatcc agttcttttg cttctgttcc tggaagtaaa ctcgctgcgt
     1381 aatttccgcc gacttttgct gcaccagtcc ccttaggagc agcacgatcg taatcagata
     1441 caataaaatt cgttggtttt agtccacctt tgaaatacgc tcctactggc gtacagaaga
     1501 cgacaaataa atattctgga gctggatgga caccaatgtt ttcaccgacc ccaatcagta
     1561 aagggcgcaa gtataatgta gcgcctgttc catagggcgg cacaaaatct tcatttgctt
     1621 ttaccacttg cttgacagca tcaacgaaca tcttttcagg gaccattggc atcagcaatc
     1681 gtctagcact ttgattcatc cgtcgactat tttgttcagg tcgaaagaga ttgaccttgc
     1741 cgtcttttcg acgataagct tttagacctt caaaacattg ctgaccataa tgaagcgctg
     1801 gagagccttc atgaatcgtc aggtaattat cttctgtcaa ttctccttct tcccattgtc
     1861 cgtctttcca tttggcaata aaacgccaag gagttttgat ataagaaaaa cctagattgt
     1921 tccaatcgat ttgcatatac ttaccacctt cgttattttc tccacatttt atcattatcc
     1981 atattatttg tcattttatt ttcagctttt ttccttcatt atagttattt ttgctatttc
     2041 cttttttgaa aacttcttgg tacaatacag aaagaatcaa attttagaaa agaggatttt
     2101 atgttttcat tattagcaac tgccggtacg acagactctt ctggcgagac attgacagat
     2161 caagctgtca gcaaagtaaa tgcgtttcag cggttttggg acgggattga ttgggacgcc
     2221 attttggctg cctttatcca aaaaagttta tatctgattt ttttgatcgt ccttttttgg
     2281 attcttcacc gtgtgggaaa atatctgatt gataagtctt ttaatcagta ttctaaaaaa
     2341 gccattctaa acgagagccg cttaaagact ttacatagtc ttttaaatac tatttttcat
     2401 tatacccttg gtttcttttt tatctatgca attttatctg ctatcggtgt gccgatcgga
     2461 tcacttttgg ctggtgccgg aattgcaggt gtggcaatcg gtcttggtgc ccaagggttc
     2521 atgagtgatg ttattaccgg attttttatt atcatggaac aacagatgga tgttggggac
     2581 tacatcaagc tagcaaactt aacgattgaa ggaaccgtcg tatctgttgg tatccgtacc
     2641 cttcagctga aagcaacgga tggtactgtc catttcatcc cgaatcgaaa catcaccacg
     2701 atcagcaatc tctctcgtgc aaatatgcaa gtacttttag atattcggat tgttcctgaa
     2761 gaaggatatg acaaaatcta tgagatcatt gatcgagtaa atcgtacatt agctgaaaaa
     2821 taccaagaag agctccaaac tgaaccttct atctttggat tagtggatct tggaaacagc
     2881 aattttgcga ttcgtacggt ctgctacgca ttgaacggaa aacaatatgc cttaaaagaa
     2941 gagttcttga gctcctatgt caaagaattg acagcttctg gtttcacgat tccgaacagt
     3001 ccaattgctg tcggaaaata atttggacaa acgatgcaac gaatctcact aaaaagagcg
     3061 tgggacaaaa gtaaagaaca cttttgtc
//
LOCUS       DAFLWZ010000155         3082 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000155 DAFLWZ010000000
VERSION     DAFLWZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.163"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(125..547)
                     /locus_tag="L1V38_002891"
     CDS             complement(125..547)
                     /locus_tag="L1V38_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317355.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            861..1475
                     /locus_tag="L1V38_002892"
     CDS             861..1475
                     /locus_tag="L1V38_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317356.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(1499..1849)
                     /locus_tag="L1V38_002893"
     CDS             complement(1499..1849)
                     /locus_tag="L1V38_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1317357.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1843..2106)
                     /locus_tag="L1V38_002894"
     CDS             complement(1843..2106)
                     /locus_tag="L1V38_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBN1317358.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            complement(2431..2610)
                     /locus_tag="L1V38_002895"
     CDS             complement(2431..2610)
                     /locus_tag="L1V38_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317359.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
BASE COUNT          993 a          554 c          474 g         1061 t
ORIGIN      
        1 gtgtctcctg taaagttcgc tgaacttgta aagctgattc ttctttcggt aaattaattt
       61 tacttagaat atcgctatct tgataaaaat ttggtgtgtt cacaaattct ggcataaaaa
      121 atccctactt tctagttaag gttcctgaat aagtcgcaat ccaattgttt ccagctgatt
      181 tataactttg taaatacaat tttccatagt accaataacc atttcttttt tctttccaat
      241 tccgtgattg aggaggtcta gaaggccaac caactttatc aaaaatcatc gttcctgtca
      301 ctcgtatcgt tttagaagct gctcgagcaa gtaatggaga aactattaaa taattttcag
      361 taacagttaa gtcgttagtt gggttaccaa tggctattcc gttcctatct aaaggagtta
      421 attcttggtt attatctact acagtagttg gttcatttgt actatcagca aatgtaggaa
      481 ttgtagttcc agttacacta attccaatag ttaaaatacc taaagataaa ataaacttat
      541 ttttcattgt ctatcacctc gaaatcaaaa ataagaaaac gttttcttaa taaatcttaa
      601 cagataaatc aagttatata ctagaaaatt cataaaatat atttttaatg tcataatcgt
      661 ttaaattttc ttgattgaca tttatttaca aaaaatattg ccatttaaaa agaaaagtga
      721 cacatactat ttcctccatc attagttttt gtctatataa ggtataccct aactagacac
      781 gaccgcgaca ttgaaaaatc tggttttctc gtgtatgatt agggtgtttt ttaaatagtt
      841 gcagaaagta ggtaaaaatt ttgagagttg catacatacg tgtctcatcc atcgatcaaa
      901 atgaacaacg gcagattgaa gaaatgaaaa aattcggtgc agagagaatt ttcattgaga
      961 aacaatctgg cgcaacgatt actcatcgac ctgtttttca agaagcactg gatttcgtcc
     1021 gagatcaaga tatttttatt gtggaagcta ttgatcgact tggaagaaat tacgacgaga
     1081 tcatcgcttc agtcaattac ttgaagaaga aaaatgtgca gctgatcatc acaagtctac
     1141 cgatcatggc cgaagcaatt ggcaatcctc tcctggataa attcattaaa gatttgatca
     1201 ttcaaatttt ggccatgatc gctgaacaag aacgtaccga atctaaacga cgtcaggcac
     1261 aaggcattaa gattgcaaaa gcgaacggtg tttataaagg acgtcctaag ctatacagtg
     1321 ccaatgcaaa agatccccaa cgtcgtcttg tttataaaaa catcgttgag gatctaaaaa
     1381 aaggtgttgc gatcgctaag attgcaaaag actacaatgt tacgagacaa accgtatata
     1441 gaataaaaaa agacagcatg gtcaatcacg aatagttgat catgctgctg tttctatttt
     1501 atttgcttac tttttgaaaa actgttctaa ctttcatcaa taactcctca actaaactat
     1561 catgcgcttt ttccaaaaaa atacactctc tggcttcata atcaattgtc gttagttgat
     1621 ctaataatac ttttcctgtt gtcttcattt catattctga gtttatattt acatatagcg
     1681 gatagtttct agttgtacta gaaattggag caactgtaac aacgttacta taatccgcaa
     1741 taatatcatg acttaaaaca atataaggtc ttttacctgt ctgttcgtgt ccagatcgag
     1801 gtgctgtatt caataataga atatcgcctt gtctaggttt tctcaccatt tttcattacc
     1861 tactgcttca cctaaatttt gaatcgtcac atgatttctt tcatcagtgt aattttcaaa
     1921 taactgttca attgttaatt cattttctat attagccgct tcgataatta gccgcttctg
     1981 accgtttact tcttcttgta ttatcttcac tttgtcttct gtatgaattc caagatattc
     2041 cataatatac tttggcaatc taaggccatt actatttccc cattttttta taggtaacat
     2101 ttccatagta gacacctctt tctgtatata catagtataa catacataag aaaaaacgta
     2161 tatacttaat tatccttttc tattaaatta gattaacatt ccatgaatcc ataaactatg
     2221 ttaacattta tatgaaaata gtcgaaagga aatcataata tgtttaagaa aacaaaatct
     2281 ttagaatcag gtaagaaaaa aattgatctg gatactttaa agatttcata gttattgata
     2341 caaaatggaa taaaaaggac atagaaaata ttctaaatag taggaacaat taagtgctat
     2401 cacttttgtt tcttcaaatg aaaagtgacg tcactttttt agtgctggta tatcaaatcc
     2461 tgctttttct tgcgcgatca atagatctaa cgcaatacac ataatcttag attcactttt
     2521 tccgtacttc tgctttagtt gctgcaattc tttttgtctc ttttcatcta atgtcacggg
     2581 taaccgttta tttcctattg caattggcat tagtactctc tcctttcatc gaaataaccc
     2641 tatgaaaaat atggctgcaa tcaacttgaa tagtagactc acaagggcta acacaaagcg
     2701 ccaaaaaatc aaacaaaata ctagtattcc taagaatact acgaagttta aatgtacagc
     2761 tgcaccatga cgcataagta tctcgccaat acacagtacg aacaacagag gaatgatttt
     2821 attcatatgg atctccttct ttctcttagg ttatcgggct ttgcccgctt atttcgcacc
     2881 acctaagcgg cgggggcggt tggagcgatt ggtgcgaaat aagaaccatt cccttaattt
     2941 caaggttttt gttcttattt cacacattct cacttttcgg tataaatgat tattgccttt
     3001 ttttcctttc aaatcgttga tatggcattc gtttacggtc aagttcattt tggatttctt
     3061 ctgtatcgtc gtaagtgtag gt
//
LOCUS       DAFLWZ010000156         2915 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000156 DAFLWZ010000000
VERSION     DAFLWZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.164"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..226
                     /locus_tag="L1V38_002896"
     CDS             <1..226
                     /locus_tag="L1V38_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBN1317360.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            226..573
                     /locus_tag="L1V38_002897"
     CDS             226..573
                     /locus_tag="L1V38_002897"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317361.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            570..1619
                     /locus_tag="L1V38_002898"
     CDS             570..1619
                     /locus_tag="L1V38_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1317362.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1634..1840
                     /locus_tag="L1V38_002899"
     CDS             1634..1840
                     /locus_tag="L1V38_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317363.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1861..2457
                     /locus_tag="L1V38_002900"
     CDS             1861..2457
                     /locus_tag="L1V38_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HBN1317364.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
BASE COUNT         1059 a          396 c          576 g          884 t
ORIGIN      
        1 taaaacaact gaatttgata ttctacacgc tctaatgtcc acacctaata aagtcttttc
       61 tcgtagtgat ttgatagaga aagttaaggg aatagaattt gatggactag ataggagcat
      121 cgattctcat ataaaaaact taagacataa aattgagaat gatgctaaat cacctatgta
      181 tattttgaca gtccatggta caggatacag atttggtggc cactaatgag aaaaagaacg
      241 ataaaaactc aattagctgt ttccttttta gcaatcgcaa cattaataat aggatcgatt
      301 agtttagtcg cattaagttt gatgaacaat cattttagta aatacgtgga agagcggcaa
      361 gaagatttgt tgaatcagta tgtatataca attgatttat tgtggttaaa tagtggggaa
      421 acatggaata gtgaagaact tgcagcacta tctgagaaag tattagagaa taatatttat
      481 ttttctatag aagacgaaca aggcaacatg gtttgggaac ttactggaaa agatttgaag
      541 tcagcacagg agaaactgaa aaaaatgcat tgaaagtttc tgagaaaaac agtgtgaaac
      601 tagacgaaac aatagaagtg aaaaagaagt taattaatga tggaaacgag tttggaaaag
      661 taacgtttta ttatttcgga ccttttgctt atacagagca cgatgccttg tttatctcca
      721 gtatgaaaca aagtttaatg tatgttgcaa ttgcagctct tcttgtatca ttcatacttg
      781 cttcgtggat ctctgctaga ttaggattgc cactaaagca tgtaagcgat tttacacata
      841 aattaactcg tggggaatat gctgataaaa tcccacaaga aacttcaatt attgaaataa
      901 attccttaat tgattcccta aatgatttaa gtaatcagtt ggagaaacag catgggcttc
      961 gaaaaagatt aactaccgat atttcacatg aattaagaac tccattagct acgcttaaag
     1021 gcaatgtgga aggaatgatt gacggagtct ggaaaataac tcccgagcgc ctacaatctt
     1081 gttatgacga aatagatcgt ctaactcgtt taattggaaa tatagaaata atcaacaaaa
     1141 ttgaagcaaa atatgatcat ttaaataaaa ctgagtttaa catatataag ttgattgaat
     1201 ccgttattga aaatttcgcc agcaaaattg agtcaaaaaa ccttcatgtt gaaatccaag
     1261 gggataacat caatatatct gcagataaag ataaaatgaa ccaagttgtt atcaatcttt
     1321 tgaataatgc tattaaattt acgcaaaagg agggaaccat taagttttct ataagtaaaa
     1381 ataaagacca tgttctttta attgttgaag acaacggcat cggtatagaa aaagatcagc
     1441 aacttcatat ttttgataga ttttatatgg ctgacccctc cagaagtaga gctttagggg
     1501 ggcaaggtat cggattagct attgtaaaga gcgttattga agcgcataaa ggtagtataa
     1561 ctgtaaaaag taaattaggt ctaggaacta aatttgttat aaagttacca tttcaataaa
     1621 ggaggagagt tatttgtttc aaaaacagat aaaaattgct aaactagtat gtgaatgttg
     1681 ggcaaaaaaa atattttttc aactgatttc gatagatagt gtcgaaaaag ttcatttaga
     1741 tatcttatca aattctgtag taatcttttc taagaaggac ttatcaatag ctacaattaa
     1801 aaaagaagtt tttggattac aaatttatga gatgacctaa atgtgattaa ttaaaggagg
     1861 atgaagacag tgaaaaagat gacaaaatta gtatttgcaa gtcttggaat tattgtattt
     1921 ttaggagcgt gtagcaatca aagtgaatcg aataattcta atagcacaaa cgaggaatcg
     1981 acttctacag cgtctagtga aatgaatagt atggagggaa tgaatcacga aggtatggtt
     2041 ccttcttcaa tgaaagatgc tgcgaaccct aaattcccgg tgggaagtaa tgttatactg
     2101 ctaggcgatc atatggaagg gatgaaaggt gcaaatgctc aagttgtagg ggcctttgat
     2161 actacaatgt atgaagtaag ctatgagcca aaaactgggg gaccaatggt taacaatcat
     2221 cgatgggtag tacaagaaga gttaaaagat actgagactg tagcaaatga gggcgatact
     2281 gttatcttga atgccgatca catggatggg atgatgggag ctgaagcaaa agtagataaa
     2341 tctattacag gaactgttta cgttgttaat tacactccaa ccgatggtca agaagaagtt
     2401 aagaatcata tgtgggtaac tgaagatgag atggaatatg acgaaaataa tgagtaattt
     2461 tatatactaa accaacaagc tggtacatgg tcttcgtatt ctcaacatga ggaatatgag
     2521 ctctttgtta ataaggactg atgagttgtg caaaatcaaa tctgggtcag aacgaacctc
     2581 attctggctc agatttttgg ctcttcgaca tttagtgctg gtagagagac aactgaaaat
     2641 ttagtcataa ccagttaggc agagtgctta actggttttt gttcgcattt attattcttt
     2701 tgatattggc tgcttgccct tcaattttat ttggtttctt aatcaactct tcatataacc
     2761 ccaaatcata tattaatgag gtgcctccta ttcctataaa tctatctctt ctttaatagt
     2821 atgagaaaag tctactcttg tagatttaaa ttgtcaacaa aaaatttaca gatgtaaatg
     2881 ataagttgaa tagagaaaga taaattattt ttttg
//
LOCUS       DAFLWZ010000157         2858 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000157 DAFLWZ010000000
VERSION     DAFLWZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.165"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            49..1527
                     /locus_tag="L1V38_002901"
     CDS             49..1527
                     /locus_tag="L1V38_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBN1317365.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(1595..2686)
                     /locus_tag="L1V38_002902"
     CDS             complement(1595..2686)
                     /locus_tag="L1V38_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBN1317366.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT          999 a          514 c          455 g          890 t
ORIGIN      
        1 gaagaaaaaa ttgtttgtta ttattagcaa caaaaaaagg agtgcatcat gaaaaagtta
       61 tctcaaaaac gtttagctca aatcattatt gattctagaa aatctctgaa aatgacacaa
      121 caacaacttg cagtagctac tggtatcaac cgtgccttaa ttagtcgatt agaatctctc
      181 gattttatcc cgtcaataca acaattagaa tcattagcag aagttctaaa ttttgaacca
      241 acagatctat ttataaatga atcaaataaa tcaaacagaa caaaacatca gtcgaagaat
      301 attgctgtag ccggtactgg ttacgtaggt ctttccattg ctactcttct tgcccagcac
      361 aatcaggtaa cagcagtaga cattcttcct gaaaaagtaa aacaaattaa caataagaaa
      421 tctccaatac aagacgatta cattgaaaaa tatctagctg aaaaaaatct taatttaatt
      481 gcaacgactg atggtgcagc cgcctataga gaagccgatt ttgttgtcat tgctgctcca
      541 acaaattatg atagtaaaca aaattatttt gatacttctg ctgtagagtc agtaatcaaa
      601 ttggtgttag aagtcaatcc aaaggcaata atggtcatca agtcgacggt acccgtaggc
      661 tataccgaaa gtattcgtaa aaaatacaat actaaaaata ttctattcag cccagaattt
      721 ctcagagaat ctaaggcatt atatgacaat ctatatcctt cgcgaattat tgtcggcacg
      781 gaccaaactg acaaaacttt acgagaagcc tctcacactt ttgcagattt actccaagaa
      841 ggagcaatca aaaaagatat cgaaactctt ttcatgggat tcacagaagc tgaagcagtt
      901 aaattattcg ctaatactta ccttgcactt cgagtatctt acttcaatga gctggatact
      961 tatgcagaaa tgaaaggact aaatacacaa gaaatcattc acggggtttg cttagatcca
     1021 agaattggca cacattataa taatccatct tttggatatg gaggctattg tttaccgaaa
     1081 gatacaaaac aacttctcac taactataac gatgttcctc agaatatgat aagtgcaatt
     1141 gtcgatagta atcgtacaag aaaagacttt atagcagatc gagtgttaga acttgctggc
     1201 acgtatgagg ctaacagttc gtggaatgca gaaaaagaaa aagaggtagt cataggtgta
     1261 taccgtctta caatgaagag taattcagac aacttccgtc agtcatctat tcaaggagtt
     1321 atgaagcgaa ttaaagcaaa gggggcaact attgtaattt atgaaccaac acttgaaaat
     1381 aacactacat tttttggttc aaaagtaata aataatttag atgattttaa aaatatcagt
     1441 cacagtatta ttgctaatcg ttacgatagt aatcttgatg atgtaaaaga aaaagtatat
     1501 accagagatt tatttcaacg agattaaaaa ataacacctc agatttgtag tgtctgaggt
     1561 gtttctataa acttttataa gtaaaaaaat acaattatac ttcataaaaa gacttatacc
     1621 actgcgcaaa tttacgaagc ccgtcacgca aacttgtact tggtttaaat tcaaaatctc
     1681 gttctaacgc actagtatct gcataagtaa ctggcacatc tcctggttgc attggaacta
     1741 gttcggtatg agattcaaag tcgtaatctt ctggtagcac ccctgctgca attagctctt
     1801 gttgtagaat atctacaaaa tctagtaggt tttccggcgt attgttacca atattataaa
     1861 tatgatatgg tgggattggt agcccatctt ccccatcaat tttctctgga gcgcactgca
     1921 taaccctctt tactccttca acaatatcat ctatataggt aaagtcacgc ttgcaattcc
     1981 cataattgaa tatttggata ttatcaccag cacgaagttt atcagtaaaa ccaaaataag
     2041 ccatatctgg acgcccagca ggaccatata ctgtaaagaa acgtaaccct gtagacggaa
     2101 tattgtaaag tttagaatat gcatgtgcca ttgattcatt acttttctta gttgctgcat
     2161 acaacgatac ttgattgtct actttatcct ctgtagaata aggaattttc ttattagtac
     2221 cataaacgga agacgatgag gcatacacta aatgttccac accagattct ccattatcat
     2281 atgaatgacg acaagcttca agaatattat agaatcctat tatgttagat tcgatataca
     2341 tatctggatt agtaattgaa taacggactc ctgcctgagc tgctaaattc accacgatac
     2401 ttggtttata attatcaaag atgaaatcaa ttgttgcttt atcagcaata gaacctttga
     2461 taaaattcca agtagatcct ggatggttct ttgcctccgt ttctatctct gataatctat
     2521 agttcttaat agagacatca tagtaatcat tcatattgtc aatgccaatg atttttattg
     2581 atgactgagt acgtaataac tcaagaacca aatttgatcc aataaaaccg gctgcgccag
     2641 ttattaatat tgttctattt gataaggacg tgtttaattc cagcattttt tagcactcac
     2701 tttctttttt tcttatgaat acatatttgt tatatattaa aaaatcttat ttagacttat
     2761 ctattgtcac ttttatcatt ctaatctttg cacgtagtag aataattata cagataggaa
     2821 attgctaagc aacccacttc tttctattat ctattaac
//
LOCUS       DAFLWZ010000158         2770 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000158 DAFLWZ010000000
VERSION     DAFLWZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.167"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(77..1876)
                     /locus_tag="L1V38_002903"
     CDS             complement(77..1876)
                     /locus_tag="L1V38_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1317367.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2000..2596)
                     /locus_tag="L1V38_002904"
     CDS             complement(2000..2596)
                     /locus_tag="L1V38_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1317368.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          978 a          522 c          480 g          790 t
ORIGIN      
        1 aaaaaacgca tatacctgcg gtggcaggtt atgcgttttt tgttgtataa agactttttt
       61 cattaacgat ttttgattag ccgactccca aaacaaaatt tagcagttta tctgaataag
      121 tgatttcttc atctgtttgt ttcacacttt catttagtag tcccatctca tcggttatga
      181 taccatccac accataaaac atcatgcgac tcatagcatc tgaatcgttg attgtccata
      241 catatacttc ttttccgtct tggtgggcag aattaatgaa gttacggttg atcgtactat
      301 attccattgt cagaaaatca gcaggcgtca cagggggccc aacaatattg aaaggtaaga
      361 tgtagcccac ataaaagttt ggttctgctt cttttaaatc tgaaacggtt tggtacgtca
      421 aactttgcaa aatatgatgg ttctctaaga taactttgcg gtatttatgg acaaatcgtt
      481 cgacaaggtc atccgaatct tttttagagg tcttgatctc aataagtaat ttttggttta
      541 gcttatgtgc tttttccaaa taagaatcaa aagaacaaac aggggcttgc actccgtttt
      601 cagtaactgt aagatttgtc aattctttca atgtaagatc ctgtggtgtt ccatttaccc
      661 ctgttaagtg acgaagattt gcatcatgca tcactacgaa atgaccatct tttgtttcct
      721 gaacatccat ctctacataa tcaggatgat agtctctgct tgttttttca agtgcttcta
      781 aagtattttg cgccccattt tgggtactca cacctctgtg agagacagtc actggttttg
      841 tctgaacagc tgaagtcaga taatccatat tgtaaagaca gacgccaata ccgaaaaaaa
      901 ctgcaaaaag agtcaaacca gtgtttttca gcgcagagaa acgcaagttg ggggcttgtg
      961 ggataaacca cttagggatc tcaggcaaga agccttcgtc atccatgaaa tcaacaatga
     1021 tataaaaaat ccctacggta gacatcacga tattgaataa taaaatccct tgtaaaagcg
     1081 tcatagcaaa cacagcgctg atcaatgcat agtctgggaa aaattgttca accatacttt
     1141 gtgccaaaat aacaacgata tatcctaaag aagaaaggag taaaatcgta ccgccaatca
     1201 caataaattg gcccgtgatg gccaaaagac gcgatttggt caatgaccag ctttcccgaa
     1261 tggctgctcg aaaaggacga tctcgtagaa tcatttccgg taaagcaaaa atcagtcgaa
     1321 tcccaatata gccaaggaaa atataaacga gtaaaaagga actgacgatg atccaacgat
     1381 tagcaaaaat aaaatccata atgaaagcgg ggatttttat ttttgacagt agatcagaat
     1441 taaaacttaa tccgctgatc ggtagaatca ataaaaaata agcaaggaaa aacaaaaaag
     1501 taatgggtct cactttcttc agctgaagta tcgtcaagtg taagagttgc ttcaaagaga
     1561 ttggttcttt ctttttaata aaaaaaacac tcatcaaaag aaaagtaaat tcgaaataaa
     1621 ctaacagtaa aatcgtcatc aaaactacga ttaacgagag tagaacccca ggatgttgag
     1681 aaaaaattga aggaatattg tcataagaca aatagtcaat tgcccctcgg tgtaaaataa
     1741 aacgggtcgt actgctcaat aagggtaaac aaataaataa aataaagcca tgcatcagca
     1801 agacatcacg gaaataagct tgtgttcctt ttaaaaagtc ccaagcatta cctaagctac
     1861 gtttcaaata attcatccta tcacctgctc ttcacattgt agcgcaaatc taatgaaaaa
     1921 ggaaagggtg cagtgtgttt tgcagaccct ttcccagatt taacattgtc aatcaatgac
     1981 taattttaca aaataaatat tatccaagaa gaccacttag atattgacct ccataaatca
     2041 aggccatact atataagaaa atcgacagtg gtttagcaat caaaatgatt agtgtatatc
     2101 gtttcactga catgtttgtc aatccagcca tcaaacataa cgcatcgtca ggagcaactg
     2161 gaagaaaaat agctagagca aacagcttct caaaacggtt ttgattatcc agccagccaa
     2221 tatatttgtt atatgtctta tcgctaatca tggaaagtat gaatggcttt ccataacgac
     2281 gccctagcag aaaaatgata atcgaaccaa tgcagattcc aatatagtta tagataaatc
     2341 cagcataagg gccaaatatc aggacaccag ctgcagtact gatccctcca ggaatgattg
     2401 gaataactac ttgcaggatt tggatgaaga caaaaataat cggtcctaaa atgatggaat
     2461 cacctactaa tcctcttaac gcattcaaat ctttgaaaac acctaaatta ataaaataaa
     2521 tcgtcagcgc gattgatagg cctaatccga taatggatat gaaatttatc agttttcgag
     2581 aggcagcaat attcattatt catcaactcc ttagaggttc tttgttaact atactttact
     2641 agaaaagcaa ctaactgcgc cattttttga tatgacagaa aacaaacaat tttgtaagtt
     2701 catcataagt ataaaagatt gatctcaaaa aaacatccaa ctaaagactt atttaataac
     2761 ttgttttttt
//
LOCUS       DAFLWZ010000159         2739 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000159 DAFLWZ010000000
VERSION     DAFLWZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.168"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="L1V38_002905"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="L1V38_002905"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1317369.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1072 a          425 c          558 g          684 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatata
//
LOCUS       DAFLWZ010000160         2680 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000160 DAFLWZ010000000
VERSION     DAFLWZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.169"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            230..1189
                     /locus_tag="L1V38_002906"
     CDS             230..1189
                     /locus_tag="L1V38_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317370.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1176..1781)
                     /locus_tag="L1V38_002907"
     CDS             complement(1176..1781)
                     /locus_tag="L1V38_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317371.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2021..>2680)
                     /locus_tag="L1V38_002908"
     CDS             complement(2021..>2680)
                     /locus_tag="L1V38_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317372.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          867 a          476 c          427 g          910 t
ORIGIN      
        1 tttatgttat ctttagctaa aacatcaaat acatgtcctt gaaattgtat cgaggcagct
       61 ggatttagtt taaattgagg aaactttacc acagctgatt caaaacactt gtcacatttt
      121 tttatttttt taccttcgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt
      181 gctacactca aaatagttcc gtcgaaagaa ttataaggag tgagtacaaa tgacctatac
      241 ccatcttaca ccaactgaac tcgtaatgat agaagcttat ttcaatcaat cacactctgt
      301 ttcaaaagta gcccatctgg tacaacgttc tcgacaaacc atttataatg tctatcgttt
      361 tcttaaatct ggtggaagcg caataagcta ctatgaacaa tataagaaaa acaaacgtaa
      421 ctgcggaaga cgtccgattg tgttaccaga tgggcaacaa gaatacattc aaaaaaaggt
      481 ggctcaaggg tggactccag atgtccttat tggtcgagca gagtttccta ttgcttgttc
      541 ggtacgtaca ctatatcgga tgtttaaaga taaaaccttt gaccctcacg atttaccaat
      601 gaaagggaaa agaaaaccaa acggacataa agaaaaaaga ggaaaacaag cttttcgccg
      661 ttcgattcag gatagaacaa ctgattatat acagttcaat catgagtttg gtcacctaga
      721 aggtgacacc attgtcggtg gaaaacataa aagtgcggtg atcacgttag ttgagcgatt
      781 atctaaagtg atcatcacct tgaaacccgc tggtaggcaa gctatagata ttgagaatag
      841 actgaatcaa tggtttcaat ctgtaccgaa acacttgttt aaatccatca catttgattg
      901 tggaaaagag ttctcgaatt ggaaaaagat tagtaatacc aatgatattt cgatttattt
      961 cgctgatcca ggaacacctt ctcaacgagg actaaatgaa cattcgaatg gcttattacg
     1021 taaagatggc ttatataaag ctatggattt taataaggta tccgaaacct ttatccaatc
     1081 ggtggcatca aaacgaaatc atattcctag aaaatcatta cactatcgca caccattgga
     1141 agtatttttg agttacgtag gtaaagatga tttgtctagc ttaatttgac aaacgaaact
     1201 ttgtaaaaat attcgattga atattctatt tggcacgact cacttggcag tatatgtatg
     1261 tcaatatttt tcatctgttt cataggtatt tcaaaatcta aactattaaa aacatataat
     1321 tccctgtaat tatttacatc taactctact aaatttatct ttggaacaat agatcctcca
     1381 cccattccac cataataaaa aaaatcttgt tctctatcaa aatagcacat attaagctca
     1441 gtttgtttat catcctcaat aattttataa atcaaaccta tataatcatg aatgctggca
     1501 aaaatttttt ttaagtcaag ttctaaatct tcttcgaaaa cacatttaat ttctcctact
     1561 gataattgat actctatatt acatgactta attagttttt tagatccccc ctccagatag
     1621 gcatatgttt caataattat gttcttttta ttgcttggca aatttccgtt atttattgca
     1681 taaattaaaa atgactgtct atttagccca taatctaata caacttcttc atactcatat
     1741 ttctttaaat atttaatatg aaaatatgct gaattaatca aaactcgagt gttactgttg
     1801 ttatttattg ttgttctatt gtgtataaaa ttgtataggt tgtcatattt tcttggttta
     1861 gtgaactact caccacttag ctaaacctaa cggtttctta cgtttgaagt gggagcttct
     1921 tgggaagaga gcatacttga tagcgtatta ctttactaac agaggtgcct cttatttacc
     1981 aagctatccc cgtagttcct acggttcttg tttatttgat ctaagccaat cccatagagt
     2041 gtagccttag accttcggtc aggatattga tactagcgtt gatatctcgg tcatgatgag
     2101 tatgacaaat agggcaagtc cattttcgaa tttcgagaga tttcttgccg tctttatgtc
     2161 cacaattcga acagatttgg ctagatggaa accacttatc tactttgatg attttccgac
     2221 cgtaccagtc agccttgtat tgtaatttag acacaaaact agaccaagaa acatccgaaa
     2281 tactttttgc tagtttatga ttacgcaaca tgccttttgt gtttaagtct tcaatacaga
     2341 tgatatcgtg atttttgata atttctgtac tcaacttatt cagaaaatca gtacgttgat
     2401 tcattacttt ttcatgcaat cgtgctactt tacgtttttg tgtttgataa tttctagctt
     2461 caaacagatt gatacctttt tgtttagcta ataaggcacg tcttgacaac ttacgttgtt
     2521 cacgtttgag tttcttttcc attttggacg taaatttatt attatcaaat ttttgaccgg
     2581 tagaaagaat tgcaaagtct ataataccta ggtcaatacc aacagcagaa ttagatttag
     2641 gtagttcgcg aacttcttct ttgcataaca aagaaatata
//
LOCUS       DAFLWZ010000161         2678 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000161 DAFLWZ010000000
VERSION     DAFLWZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.170"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            693..788
                     /locus_tag="L1V38_002909"
     CDS             693..788
                     /locus_tag="L1V38_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1317373.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1090..1335)
                     /locus_tag="L1V38_002910"
     CDS             complement(1090..1335)
                     /locus_tag="L1V38_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317374.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1680..1964
                     /locus_tag="L1V38_002911"
     CDS             1680..1964
                     /locus_tag="L1V38_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317375.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1967..2383
                     /locus_tag="L1V38_002912"
     CDS             1967..2383
                     /locus_tag="L1V38_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317376.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
BASE COUNT          882 a          498 c          430 g          868 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc cccttacaaa taaataataa cctttaacaa
       61 ccaactcgta aataggttgg ttgttattat acaaaaggat attagtactc agataaaaag
      121 ttgttagtac tcagataaaa agttgttagt actcagataa aaagttgtta gtactcagat
      181 aaaaagttgt tagtactcag ataaaaagtt gttagtaccc ttctgtatcc gttgggagag
      241 taaggctcaa ctgcccccta aaaagggttc taaaaaatct ttaaaaaata aataaaataa
      301 acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc cactttttaa aataaacagg
      361 ttcgcgcatg atattaaact gccaatctag ctccctatgg tcgctgtaag aaggagtgat
      421 cgctacgctc tcacatttta cttgcagcag tcgcctttag gctccttcgc caaaaataat
      481 tcattaggga ctcctttgtg gcgtcctgag agctcgtcta agccgttcta agacaagatt
      541 cgataaaaac tatgtccttc gttctaaagc gccttacagg cggtcagggc aagccctaac
      601 aaccccaagg caataaaaaa cttaggctta tttttgcttt tttattgtat aattgattgt
      661 cgcctatccg acagtcttgc gactggaagg aggtgtgttt cgtgttcact aactttattt
      721 gctcccttct tgttgggctt ttaagcgctt tgttcagtta ctggttgaat aaccgaaaca
      781 agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa agccccagag aatccgacct
      841 ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa tcaaattata acagaaataa
      901 atatttattt caaaaatatc ctacaaaagt ctaaaatccg taattatttc ttatatgcaa
      961 catttacaaa taaagtcgct ctgagagctc gtatttttcg atttaagacg ttttatttag
     1021 tttttggtgt atttcattgg tccaagctaa aaaactctta gaagcgattt tagagccatt
     1081 taaacccact taattatatt ctccatgaaa ttcgctccat gcgtcaaaag ctgcgtctga
     1141 aattccgccg tcttcgttca ctagttgcat taatttttcc aacgatcgtt ttctttcggg
     1201 tgtcatattt ttatattcca acaatttttc gtctgttaaa tcgaacttga ttgcttgaat
     1261 tgcttgctct aatttttcta agttttgaaa atattcgtaa ggaaattttt ccattttttc
     1321 tttctccagt ctcacaattt ttctagaaat aaaatcactt ctttgccgtc tatactctca
     1381 aaaaaaatgt cgtttgaaaa actaaataaa tttttgatcg tgcattttta aatttggtta
     1441 tcgattacac gtgcagcact cccccccgaa ttttaaagag cataaggaaa cgtgtaccca
     1501 ctttctaaaa aaagtgggta gataggctgt gcctatcacg tttctcagaa aaaaatttga
     1561 tatcactttt tcgccatcgt gggtagctta tgtatagcat tttggcaaaa aacagctata
     1621 caaatatagt atttgtatgg tatacataaa ttatacataa ttgcaaaagg agatttttta
     1681 tggacatttt agttcggaat attgatccaa agtttgttgc aacaatagac aaacgttgcc
     1741 aagaactcac gaataaaaca ggagaaaaat ggagtcgaaa taaatatcta aaagttttaa
     1801 tcgaaagtga ttttgaccgt caacttacga cttacaaaaa agaccaattc gatttattgc
     1861 tcgataaatt tattgctatc caaacagaaa atactcaaat attaagcgag tatgtctaca
     1921 caaataatca aatcattgaa atgcttatcg gaggaatgat ataaccatga gaaaaacttc
     1981 tgtccaaaaa catgttactt tgtaccctag tcatgttgac gttttagatt ccatcatcga
     2041 aaaaaatcca gatatcaata actactcgga agccattcgc tttttatgta tgagttatga
     2101 acccgatacc aacacgacca ctaccagcaa tcaggcaaaa ctaaatgcta tgggaaaaga
     2161 aatttccatc atgactgaaa tcatcgcaga atttgctgat ttatatctaa aagatacagg
     2221 cgttcttatt ggcacaaatt ctaaagtata tcaagaagtg aaagaaaaaa tcgaagctaa
     2281 actaaatcca tcaaatcgaa atcgaccaaa gaatcatcaa aaagaaacca gtcaaacagt
     2341 cacttctaga aatttcgacc caacaaattt tctaaaacga taaaaaacag ataggagtta
     2401 ttcctatctg ttttttattt agaagcccca tacaatatgc tagaatgtac tagcaatctt
     2461 agtcggttgt aagggacttg tctacttgct taatgtaagg ggggcgagtt cttttttatt
     2521 tattcttcta accagttacg cagagaaatc tttggcaaat ctgacgttag gcttgaaaaa
     2581 gtaaattcta atttggcgat tttattgccc ttttttgctt ttatttttgt gactttaaga
     2641 tcattgaagt atttttttag ttctcgtaat gcaggatt
//
LOCUS       DAFLWZ010000162         2610 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000162 DAFLWZ010000000
VERSION     DAFLWZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.171"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(155..520)
                     /locus_tag="L1V38_002913"
     CDS             complement(155..520)
                     /locus_tag="L1V38_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317377.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            728..1210
                     /locus_tag="L1V38_002914"
     CDS             728..1210
                     /locus_tag="L1V38_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317378.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1407..2297
                     /locus_tag="L1V38_002915"
     CDS             1407..2297
                     /locus_tag="L1V38_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBN1317379.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          891 a          424 c          522 g          773 t
ORIGIN      
        1 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
       61 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
      121 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
      181 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
      241 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
      301 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
      361 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
      421 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
      481 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
      541 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
      601 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
      661 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
      721 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
      781 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
      841 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
      901 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
      961 gctgctttac ttttcttgct tattagtatt tacatctacg ttttctttgc tgcctcgctt
     1021 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1081 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     1141 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     1201 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     1261 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     1321 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     1381 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     1441 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     1501 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     1561 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     1621 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     1681 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     1741 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     1801 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     1861 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     1921 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     1981 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2041 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     2101 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     2161 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     2221 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     2281 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     2341 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     2401 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     2461 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     2521 tgaagacaaa tttgaataaa acttagaccg atatgcggcg cgttctgtgc gccgcatatt
     2581 tttttagttt tcaaagatca gaccttgttg
//
LOCUS       DAFLWZ010000163         2472 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000163 DAFLWZ010000000
VERSION     DAFLWZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.172"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            169..2322
                     /locus_tag="L1V38_002916"
     CDS             169..2322
                     /locus_tag="L1V38_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBN1317380.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          848 a          428 c          546 g          650 t
ORIGIN      
        1 atgaaaaaaa tagttggata tgtaacttta agtgattgct gtgaaacaaa aagttgattt
       61 tatcttgaaa ttaggtaaag aatttcttgc tccgcccatt ttttcttttt tattaagaag
      121 tttttgggta caatgaagca tgaatgtaaa taggcggaag gataggaaat gatgaaagat
      181 tttatgaaaa aaatattaaa tacttcttgg ttagaaaaaa taagaaaagg tgcacaagaa
      241 cctaagaaca aaacgtttcg ccggtcccat gttccttttc gcttaaattt tctttttttc
      301 attatattta cgttatttgt tgcgttgatt gctagattgg gttatttgca gatcgtgaac
      361 ggcgaagaga tggaggcgcg agtgaagtct acttctacga ttacggtcca agaaagtact
      421 cctcgcggaa tgatctacga ctccacagga aaagctttag ttacgaataa agcgaatcag
      481 gccatcacat atacgagagg aacacaagtt acggctaaag atttgcttga aatcgcaacg
      541 aagctgaact cgctgatcga tgttccggta gatgaaaatc tgacagatag agataaaaaa
      601 gatttttggc tggctgatcc caaacatttg aaagaagcca caaaaagact ttcggcaaaa
      661 gaaaagcaat tagggaacag cgaacaatat agtgcgatgg tcaataaagt cacagctgat
      721 gagattaatt taaacgagga gcaattaaaa attgctacca tctttaaacg gatgaatagt
      781 gcatatgaat taaacactgt ctatatcaaa aactctggtg ttactgatca agagttagct
      841 gttgtggcag aacgcgcttc tgaacttcca ggagtttcga ctggcacaga ctggacacga
      901 gaatataatg cagcaagttc actgaaaagt attcttggca gtgtgacgac tgaaaagcaa
      961 ggacttccag cagatgaagc agagaaatac ctagcaaaag gttattctcg gaatgaccgt
     1021 gtaggacaaa gttatttgga aaaacaatat gaagatgtcc tgcaaggaac caaaacccaa
     1081 tatgaagttt cccttgataa tgaaggaaat gtttcgaatc aaaaagaaat cttctctggg
     1141 gaaaaaggtt ctaatttaat gttatctatg aatgcagaat tccaatcaaa agtagaagaa
     1201 attttgaaaa ggaattatca aacattgatc aacaacggca aagcacagta ttcgcctggt
     1261 gcttatgcag tggctatgaa tcctcagaca ggagaagtgc tagcaatgac tggtttcagt
     1321 catgaacaag gttccaaaga aatcaccgag aatgctttag gcacgattac tagcgccttt
     1381 gatccagggt ctgtagtcaa ggctggtact ttgacagcag gctgggcaag taacgcgatc
     1441 agcggaaatc aagttttgat tgatgagccg attcgtctgc aaggtgcttc agaaaaaagc
     1501 tctgtcttta atcgaagcgg acaagttgct cttgatgcag tcaaagcatc ggaattgtct
     1561 tctaatacgt atatgatcaa agtggcgtta aagatgttag gactagacta tacacctgga
     1621 atgggactac ctagtttaga tgaagaagct aaagcttatc agcaattgag agactctttc
     1681 aaagagtttg gtcttggtac aacgactggg atcgatttgc cgaatgaatc tcctgggatc
     1741 tcacgttctg ttgattatat gaagaagttc aatgcggata atggcaaaga atggtatgct
     1801 ccaggtaact ttaccgattt ggcatttgga cagtttgaca catatacacc aatccaatta
     1861 gctcaatatg cttcaacagt cgctaatggc gggaaacgag tacagccgca cctagtcaaa
     1921 gcgatctatg gcaatgacga aaatggaaac ttgggtgaag tgaagaaaga aattggcaca
     1981 acagtagaaa atacggtcaa tatttctgca gaaaatatgg cgatcctccg tgaaggattc
     2041 caccaagttg tccatggtac cgatccttac acaacagcca aaccattagc cagtgcgaaa
     2101 atggaccttt ccgcaaaaac agggactgca gaaacggttg cggaaggtca tccagatatt
     2161 gcgacagtca atagtaatat cgtggcatac ggaccaacag acaatccgga aattgccatc
     2221 agtgttgtct tgccgaactt attagacgaa caagaccaca taaacttgac gattgctaaa
     2281 gaaataatgg acgcgtatta tgatatgttc atggcaaaat aaaaaagagg tcgtgaaaaa
     2341 gccgcttagt ttcgagtatg aagaaaaatt ttgtgaaaat agcttctcac atttttgctt
     2401 aaatttgact tcataccgag aaactggctt ttgaacaccg tttactcggc aaaaaaggtt
     2461 gtgacaaaaa tt
//
LOCUS       DAFLWZ010000164         2401 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000164 DAFLWZ010000000
VERSION     DAFLWZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.173"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(4..249)
                     /locus_tag="L1V38_002917"
     CDS             complement(4..249)
                     /locus_tag="L1V38_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317381.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(266..1117)
                     /locus_tag="L1V38_002918"
     CDS             complement(266..1117)
                     /locus_tag="L1V38_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1317382.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            1283..2287
                     /locus_tag="L1V38_002919"
     CDS             1283..2287
                     /locus_tag="L1V38_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBN1317383.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT          771 a          404 c          485 g          741 t
ORIGIN      
        1 tttctatttt ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg
       61 ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat
      121 ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa
      181 gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat
      241 tggatccata aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc
      301 cgactacacc atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa
      361 ataattcagt attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt
      421 cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga
      481 tttgtttcat ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga
      541 ggatcatatc atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa
      601 ggaaaacttg attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt
      661 ggggtaagaa attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa
      721 atgctcgcca tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg
      781 gccagtggat caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa
      841 aagaagacat cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata
      901 tctcttctct aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt
      961 atccttgggc agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa
     1021 cagcgacatc cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac
     1081 catttgatag acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg
     1141 ttcaactata agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga
     1201 aatttttgtt taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac
     1261 taagacagaa gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat
     1321 tgacagagaa actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata
     1381 tattcgtgat tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg
     1441 acaactagca gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt
     1501 ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc
     1561 acctagtgca gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt
     1621 attgaaagtc aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat
     1681 cgacaaccgc ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga
     1741 agcattcgct gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt
     1801 ttctggcaaa aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc
     1861 tttagaagaa aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga
     1921 gacagaagaa tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga
     1981 aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc
     2041 aaaaatggct tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt
     2101 aaaagaagta caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa
     2161 cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt
     2221 gaataatccg gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg
     2281 tttataaaaa tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt
     2341 gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa
     2401 g
//
LOCUS       DAFLWZ010000165         2395 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000165 DAFLWZ010000000
VERSION     DAFLWZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.174"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            316..570
                     /locus_tag="L1V38_002920"
     CDS             316..570
                     /locus_tag="L1V38_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1317384.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="L1V38_002921"
     CDS             571..888
                     /locus_tag="L1V38_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1317385.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="L1V38_002922"
     CDS             1447..2382
                     /locus_tag="L1V38_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317386.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAFLWZ010000166         2388 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000166 DAFLWZ010000000
VERSION     DAFLWZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.175"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            26..1126
                     /locus_tag="L1V38_002923"
     CDS             26..1126
                     /locus_tag="L1V38_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1317387.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            1133..1528
                     /locus_tag="L1V38_002924"
     CDS             1133..1528
                     /locus_tag="L1V38_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1317388.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            1525..>2388
                     /locus_tag="L1V38_002925"
     CDS             1525..>2388
                     /locus_tag="L1V38_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1317389.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQN"
BASE COUNT          950 a          265 c          452 g          721 t
ORIGIN      
        1 aaaaaagtat aaggaaaaga gagttatggc aaagtattat aataaaaaaa ttcttataat
       61 ggcaaacaac gatgatggtc tttaccgttt tcgaggaatg ctcataaaaa acttagtaga
      121 tcaaggtaat gaagttattg tatctcttcc aaagggcaag aatattccta aattaattga
      181 acttggatgt caaattattg aaactccaat agatagaaga ggaattaatc caaaaactga
      241 ctttaaacta ttttttaact attgtaatat tttgaaaaaa ataaagccag atatggtcat
      301 tgcttatact atcaaaccaa atatatacgg tggattggca tgtcggttaa gaaaggtttc
      361 ttatgcatta aatataaccg gattaggaac ggcatttcaa aaaaaggggg ttttgaaaag
      421 tcttattgta tttttgtata gattagcagc taaaaaatct aaggtcatat ttttcgaaaa
      481 ttttgaaaat atgaaaacat ttcagacttt acaaattgct aaacaaagta aatacaagct
      541 attaaacggt gcaggagtag atgtagaaca ctttagttat ttagaatatc ctaaagatga
      601 gcaagttcat tttttattta ttggaagaat tatgaaagag aaaggtgtag atgaactttt
      661 tgaagcaatg aaaaacttat atagtgaaga gaaaaattgt gtacttgatg tccttgggta
      721 ttttgaagaa gattacggca taaaaattga aaaatacgaa aaagagggat ggttaaaata
      781 tcatggatat caatctgata ttcgtccctt tgtagaaaga gcacattgct ttgttttgcc
      841 tagttggcac gaaggaatgg caaatactaa ccttgaatca gcagcatcag ggagaccaat
      901 tattacaagt gatatcccag ggtgtaaaga agcagttatt gaatcgaagt ctggttattt
      961 atgtgaaaga aaaaatagtt gtagtctcta taattcgatg aataaatttc taaaattatc
     1021 atatgagcag cgcattaaca tgggaaaaat ggggagaaat tatatgatta aaaaatttaa
     1081 taagaagaaa gttgtcgatg aaacaattaa atcattattt agttaaaaag atatgttttg
     1141 caaagtatgt gatagaaaag agggattctg tggcttcaga atagatatca aagaattggc
     1201 aaaagtttct gatatttttt tatttactac attacaagaa ggaatgccaa gatctatgat
     1261 ggaagctatg gcaagtggat tgccatgtat agcaagtaaa atccgaggta atgtagacct
     1321 tttagtggaa ggaaaaggtg gatatcttgt tccagctaaa gatgcagaat tagtagcaga
     1381 gtgtttgaga gaactaatca ataataaatc tcttagaaag tatatgggaa atgagaacct
     1441 ttccagaatt aaagaattcg aggttagtat cgtaaaaaaa agaatcaaag aaatatatga
     1501 agaagttata ggtgagagtg taaaatgaaa aatccaatgt tttcaataat agtacctatc
     1561 tattgcgttg aaaaatattt gaaagattgc ttagattcaa taagaaatca gacatttaaa
     1621 aattttgaag caatactagt tgatgacggt agtcctgacg aatgcccaga aatatgtgac
     1681 tattattccc aaatagatgg acgtttaaaa gtaattcata agaaaaacgg tggaataata
     1741 gatgcacgga aaacaggagt cactagtgct atgggagagt atatagtttt tctagatggt
     1801 gatgattggc ttgcaaatac ttatttagaa aaatatgcgg aagtaattac taagtacaat
     1861 ccagatataa tatgtagtgg gtattttgca tcacgttcca acaaaattag aaaaagagaa
     1921 ttgtcttgct cgtttggata ttatgacaaa gataaaatta taaatttgat ttatcctaaa
     1981 ttaattgagg atgaacatgg agagtatttt agaccacaat tatgggcaaa agcttttaga
     2041 actactctgt acaaggaaca acaacaagta tctgggcaag ttagtgttgg tgaagatcat
     2101 gcatgtacaa aaccatgtat ttaccatgca aattcgatat atatgatgga aaaatgttta
     2161 tattattaca gaataaacga aaattctata acaaaaaaac cacaaccata ttattgggaa
     2221 ggaccaaagg ctattggaga gcattttgaa aagcagattg atatgaataa gtatgatttt
     2281 caagatcaag tatatagaaa tgttacacac aatttattta atgttgctgt ttcacaattt
     2341 aataaacagg acaaatattt aaatataaaa aaagatatta tacaaaat
//
LOCUS       DAFLWZ010000167         2358 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000167 DAFLWZ010000000
VERSION     DAFLWZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.176"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            167..2029
                     /locus_tag="L1V38_002926"
     CDS             167..2029
                     /locus_tag="L1V38_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1317390.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2029..>2358
                     /locus_tag="L1V38_002927"
     CDS             2029..>2358
                     /locus_tag="L1V38_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1317391.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          849 a          350 c          461 g          698 t
ORIGIN      
        1 agtgcaataa aaaacgcttt ttaacagtac atgtagtcgt ctttataata gataaactct
       61 gtaatattag ttaaaaagct ataagttgca cttagttaag tgcaaacatt tcatattgtc
      121 gttagtttag aaaacgctta tattagcaat gtaaggagag atgataatgc agcagctaac
      181 aaaaagagaa aggcagcttt tgatttactt ggtggaaatg tctgaaccgg taacaatcaa
      241 aaagttggct gaaaaagaaa atgttagtgt tcggacgata aaatacgatc tagatgatat
      301 aagagagtgg ctgaatgagc ggaagcaagt cctatatagc aaacgtagtc agggaatttg
      361 gatgaatatt agtagctctg atcgaatcaa attaaaaagc gaattgatgg atgttaatcg
      421 ttttgaaata tttgcagatc aaagtctccg aatcaaacgt ttactaatta tgcttttagt
      481 aacaaaagaa gctattactg gaatgaaaat ggccaacgca ttagatgtca gcaaagatac
      541 gatcatgaat gatttagatg tgctggaaaa taattttctt aaggaaggat tgaccttgaa
      601 tcgtcaggcg cgaaagggtt tttggatcat aggagaagaa cgtctagttc gattaacgat
      661 tgaagagatt cttcaaaaag agttcacgga ttatgacatt tataaattaa tgtcattgtt
      721 attgaatggc ggtgagactg aatactttga aatgtattct gctactgcta cacctatcca
      781 agaggtattt aatcaagtaa tcattcgaat gcgacactta ctggaatttg aaaatctaga
      841 gaaactgaat tacgcggaat tactaaatat tctgattcga gtgacaattg ctaccgttcg
      901 cttacgcaaa gaggctacga ttggtcgtta tcaattggtt gctgaacaag aattagacaa
      961 aaacgatctt tcttatcgcg tcatgcagca ggtctttgat tattatcagt tgccactgtt
     1021 cgaggatgaa tatcattata tctatagtga tacattcgac acgattcacc agcaagacgt
     1081 catgaaacta gttgagaatg tgatttataa agtaagtaaa gcaatcaacc attcttttta
     1141 tcaagatcca caattgttga cgaatctgta tgctcattta tccatgcgat tatcgagaaa
     1201 gaaaaaattt gtcaatgaat ataatccttt taaagaagat atcaagcaga aatacccgga
     1261 attatttgat gcgatcaagc aagcagttcg acaagaaata agtgaacaaa atattctgat
     1321 caatgattct ttcgtggcat atattgcctt acactttttg gtttcctacg aaagagaaga
     1381 agatctacga agcgttagag ccgtctacat ttgttcaaca gggttgggtg tgactagtct
     1441 gatcaagcaa aagatcaatg aagaattaaa taatatcact atcgtggcat ttgcttcagt
     1501 attgaatgcg caagaaatga ttgctaccaa agatcctgat ttggtgatta gtatttttcc
     1561 aattaatggc atcgatcgtc ctttcatcaa agtccatcca ttacccactg aacaggactt
     1621 gaaaaaaatt caacaaataa taaaaaaaat acttgcttct tccaatcagc aggaaaggca
     1681 taacttgaat cttagagaaa cgtccatcaa taaagatact ttagaagact ttagcaagga
     1741 attgattttg aaagcttata cgatttatga acgtttactt gtcattttgg aagcagaatt
     1801 gatccaagaa tatcgagaag cttttttgct tcatgtattc ttaatggttc atcgtatcac
     1861 atttgatcaa caatatatgg cagaaggtcg tcaagtagac cagattattt tagacaaagg
     1921 aacactggta ggaaaaatcg aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc
     1981 agaaatcagt gcattattct catatataaa agaaggagcg tcaagttagt gaaaatgtca
     2041 gacgaggctt taaaaattat cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt
     2101 gatctaattg aagagcgatt agtagaacat gctattgtac caaccgagtt gcagtggacc
     2161 attctaatta atcacttgaa tgagatgctg aaacgttctc aaagaaagga aacgattccc
     2221 gtagtcgatc gggatttgtt caaagaagta tccaaagaag ccataactat ttctgatgaa
     2281 atagttagaa gtatcggtaa tttaaccgat gatgaaatat atgttttgtc gattcatttt
     2341 gaaacagcaa aaaataat
//
LOCUS       DAFLWZ010000168         2342 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000168 DAFLWZ010000000
VERSION     DAFLWZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.177"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            100..1059
                     /locus_tag="L1V38_002928"
     CDS             100..1059
                     /locus_tag="L1V38_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317392.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(1312..1461)
                     /locus_tag="L1V38_002929"
     CDS             complement(1312..1461)
                     /locus_tag="L1V38_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317393.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1923..2135
                     /locus_tag="L1V38_002930"
     CDS             1923..2135
                     /locus_tag="L1V38_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317394.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          849 a          371 c          404 g          718 t
ORIGIN      
        1 ttattacgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt gctacactca
       61 aaatagttcc gaccaaagaa ttataaggag tgagtacaaa tgacctatac ccatcttaca
      121 acggatgaac ttgtaataat agagtcttat ttcaaaatga atcaatctgt tgctaaaact
      181 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
      241 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      301 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      361 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      421 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      481 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      541 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      601 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      661 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      721 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      781 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      841 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      901 ttattgaaat ctatggattt caattcagta gatgaatttt ttattcaatc tgccgcatct
      961 aaacgaaata atattcctag aaaatcactg gattatcgaa cacctttgga agtatttttg
     1021 agttacgtaa gtattgatga tctgtctaac ttaatttgac aattaagatt atattaaata
     1081 ttatacagat aataacggaa tattatcatc gaaacagcta acaaaattgt cataaaaaac
     1141 gagatggttg atattagaac ttgtgttttt gtttaggtct agagataaag agagacaatt
     1201 tccaaatata tgtaatgaat acaaaaagac gtttgtcgcg gattaccgtt acaaacgtct
     1261 tttattgatt ttccgagatc tcatcagtcg ccatttggaa tggttcactc cttatctaga
     1321 ttcgtttaat gctcggactg cttgttcgat tgtaatacca aacgcaacgt tattttcgtt
     1381 ttgtgcatca atcgccataa aacggttaga agttgtatca aaagctacgc ggtattgcat
     1441 atttgttttt gtaaacgtca taaaattcat ctcctttgta atgtaattta gttcttgaaa
     1501 gtttccttta aactttcgaa cttataccaa gtttagcatc gtacgttttt tgatgcaatt
     1561 aaaaagcatt tatcattttc cttatttatt ttttcttaaa tggtttagct attttctttt
     1621 aatccgataa gtagcccaat catcaaggtt acaaatacta ttgcttgaat ataaatcata
     1681 tgctcacctc tttataaata acttagcaat ataaagaaaa aaacgcacga acaacatagg
     1741 aatataaaca aacgtttttg tcacaacgtc taagatcgtg ttaaaaaata gttatctaaa
     1801 aagcagaaag atactcaaaa taaaaaataa aaaaatggat aaaaacgttt tcaaatacaa
     1861 ggtaatttgt tattataaaa taaagaaaaa acaaaataaa aataaagaaa agagggaatg
     1921 aaatggtaaa agcagaagta ggaagatctt atatatgcaa accgatcgga gtatctcatg
     1981 aactaatcgg ctgtattgaa cgtacatata tcaacacggc tgtcgtgtat gttgaaagtt
     2041 atgaccaacg agactatcaa cttatcaatg aaagcaagta tcgcatgctc gtaaaattct
     2101 gtgatattag cgcacctgct gaattggttt cttaaacagt atttttgaga attcgcaaga
     2161 actcccttat aatataaata aagacagaag ggagcgagaa gatatgccaa aaagaaaaag
     2221 ttcagggaaa atgggaatta ttcttgcagt gatctctgca attcctgcta ttttagctat
     2281 tgttcgtgcg atgaaggaat caagagaaag ttaagcacac attatgagcg tcaaacaaaa
     2341 aa
//
LOCUS       DAFLWZ010000169         2337 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000169 DAFLWZ010000000
VERSION     DAFLWZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.178"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            106..2271
                     /gene="acm"
                     /locus_tag="L1V38_002931"
     CDS             106..2271
                     /gene="acm"
                     /locus_tag="L1V38_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBN1317395.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
BASE COUNT          921 a          353 c          456 g          607 t
ORIGIN      
        1 tttagttaaa agattggaaa tgagtggggg aggaattgaa gaaaggattt ttgagagatg
       61 atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa aaagtgtaga
      121 aatattattt tatcaatgtt atttattatt actaatataa catcactgat tcctgttcat
      181 gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac cgtggaccca
      241 acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa
      301 aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa tattcgcggt
      361 gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg aactttaacg
      421 gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct agactcagta
      481 gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat
      541 acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca
      601 gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct acctgaagat
      661 actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt tgaacaacca
      721 gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac gtttgaaatt
      781 aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat ccaacaattt
      841 ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta cattgaaata
      901 actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa gacgatcata
      961 gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa agaatttaat
     1021 aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc agcttctggt
     1081 ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa tgacacagag
     1141 attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc tattcaagga
     1201 cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa
     1261 gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt tgatccacta
     1321 agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt cagtttacct
     1381 atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa cggtggaacc
     1441 actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca
     1501 gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac ttgggaagat
     1561 atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga agtagatcaa
     1621 aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct agtcgttaca
     1681 aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga caatgagaac
     1741 caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg tcaaccgatc
     1801 caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa
     1861 tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc cgaatacagt
     1921 acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac aaatatatct
     1981 ataccaggta gccatataac accgtggaaa aattttccag agaagacaga gagagagaaa
     2041 attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga atccagcgaa
     2101 caaagaagca attatattag taagagagct gtacctaaac agataacaaa taaatcaaaa
     2161 agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat tggtttattg
     2221 atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta gttagaatat
     2281 aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt ataatcg
//
LOCUS       DAFLWZ010000170         2307 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000170 DAFLWZ010000000
VERSION     DAFLWZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.179"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            142..1755
                     /locus_tag="L1V38_002932"
     CDS             142..1755
                     /locus_tag="L1V38_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1317396.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          724 a          408 c          448 g          727 t
ORIGIN      
        1 gaaaaaaatt tttaggtttt atccacaaat tatttctcta tattttctgt ctattcaaaa
       61 taaacaataa ttttccggca caattatttg ctgtttttta ccataacata gtacgatcaa
      121 cgtagaaaag gagatgtttt tatgaaagtt gttgtcattg gcggtgtagc tggcggtcct
      181 tcatttgcca ctcgtttccg tcgattgaat gaagcgcacg aaatcattat ctatgaacgc
      241 ggagaaaata tttcttatgc aagttgtgct ttgccttatt atttaggagg tgtgatcact
      301 gaccgtgact cgctgatcga acgtacacca gaaatattga aaacaaaaaa caacatcgat
      361 gtctttacta aacacgaagt aacagcaatc gatccttcta ctaagcgatt aacagttaaa
      421 gacctatcca caaatgaaga aataaaaaca gattacgata agttgatcat ctcttctggt
      481 gctagaccag attatccgga tattcccgga gtttttgaag cagaaaacgg ctttgtcctc
      541 cgtagtgtga cggatgcgga tcgaatcaaa tcgttccttg aagaaaaaaa tccacaacat
      601 gtcgtcattc ttggtgcagg tgttatgggt ctggaattag ctgagaattt caagcatcgc
      661 ggcttagacg tgactttaat cgatcaattg ccacaagtcg ctttccctta tgatccagaa
      721 attgctaatt tagtttatga caaattgctg aaagaaggat tagccgttca tttagaaaca
      781 agagttactg agatccgtga taaaggtcga gaaatagtat tatcagatgg ctccgtcctt
      841 tctgctgata tgctaatttt tgctgttggt gtttctccga agaatgaagt ggtgaaagca
      901 accggcatac aattatcaga tacaggtcag atcattgttg atgaccagtt acaaaccaat
      961 ctgccggaca tctatgcgat tggcgatatt atcgaaacga ctagtgtagt gactggtcag
     1021 ccgatccaaa gtatgctttc cagtgcggcc aatcgtcaag gacatatgct ggcagatatt
     1081 ttaaatggta cgcctatgcg ctatcgcgga tatattggtg caggtgtcgc aaaaatcttt
     1141 gatcatacag caagttatgc gggaatgaca gaacatgaat taaaagcatc aggcataaca
     1201 aattataaaa ctgtttttat cactcccttt gaccatgcct atttctatcc agaagctaca
     1261 agattaaatc taaagctgat ttttgatgca gatagcggtc gtattttagg tggacaagca
     1321 tttggagaaa aaggtgtcga taaacggatg ggagaacttt ctgtagcaat caccggaaac
     1381 ttgacagtct ttgatttgcc tgatttggag ttgccttact ctccaccgta ttctactacc
     1441 cgtgacccgt tgaatatagc tggttatgtc gcaatcaatc aaatgacgaa tatcgtagaa
     1501 acgatcaaag caagtgatat acccgaaaac gatttgaaag aagcgttctt tttagatata
     1561 cgtgaaccta ataaagcacc ttctggcagt atctcggcaa caaaaaatat tccaatgaat
     1621 gagttacgag atcgaatcaa tgaaatccca aaagataaaa aagtttacat tactttcaga
     1681 agaggattga atacttatac ttctgcccga atcttggcag gtttgggtat caaagcgatt
     1741 ttgattgaag aataaaaaaa cgaccgcggt gggtagccgc ggtctaggag ttatttttac
     1801 ttgaggagta aaaatgaaaa agtatatagg gttgttggtt ggtatgtata tagaatagaa
     1861 gataaatgtg aagaaattgt gcattatttc ttcacattta ttaggttata gtttaagaaa
     1921 gtttaaacat tgcgcaattt aattatttta gctgtttctt ttcataaaaa aacatgttgt
     1981 gactctgaga caaatcatag tccatagtga tgtctctaga gtaactacgc ctaatattac
     2041 gaggcatcat attaatctat cagcactagt acctaaacta gcatcccttt cgaatatttt
     2101 ttcttatata ataaagtttg ctttcactcc tctaatctca ccaaatcgac tggcttgcgt
     2161 tgtgtgatac taggaactga ttggtttaga acgacttttc tattgtaatc atatttttcg
     2221 ccatcctcgt tgtcttctaa tccttcaatg aatgatccct aatgtgtgta ttaaataatt
     2281 taattttttt gttcctattt atttaac
//
LOCUS       DAFLWZ010000171         2284 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000171 DAFLWZ010000000
VERSION     DAFLWZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.180"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            290..697
                     /locus_tag="L1V38_002933"
     CDS             290..697
                     /locus_tag="L1V38_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317397.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            711..1112
                     /locus_tag="L1V38_002934"
     CDS             711..1112
                     /locus_tag="L1V38_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317398.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1114..1485
                     /locus_tag="L1V38_002935"
     CDS             1114..1485
                     /locus_tag="L1V38_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317399.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1521..1820)
                     /locus_tag="L1V38_002936"
     CDS             complement(1521..1820)
                     /locus_tag="L1V38_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317400.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1826..2056)
                     /locus_tag="L1V38_002937"
     CDS             complement(1826..2056)
                     /locus_tag="L1V38_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317401.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
BASE COUNT          832 a          302 c          367 g          783 t
ORIGIN      
        1 ttttgagggg aagtacatat agttgttgat atagttgcta atattgttag ctaatttgtt
       61 agtaaaactg tatacgaatt tagatagtaa aaaaacagtt tgttccttat atagaggcac
      121 ttttactact gattaaatgt cagatatgct tacaaatata cttataaata tgcttacaaa
      181 attagctaat atttccgttg acaaagcttt gttactattg ttaaactaaa ttgactagca
      241 aaagtgaaac ataaatttat taaataaatg taaaaattag gagaaatcaa tgtcttatag
      301 agtacaatta ataatttcag aagatgtaga aagtcagcaa tttggcacta atgttattaa
      361 taaagtaatt aatccagctc tttctattaa tgcgccttta attcctactg ctttatcatt
      421 ttctgtaaca gctgtggtgt ctgagataga ggatacagaa aagataaaaa tagtagaaat
      481 tgaagtttta aacaagaatg aaaaacaaat tttttctacg ggtgaagtat cggtaagctt
      541 gcctcctcaa gttaacgata taaactttaa tataaacgcc agaaatgtct tggttgaaga
      601 agcaggagag cattatgctg ttgttaaatt taatggaact gagattggaa ggcaaatctt
      661 tgatatcaag gtcaacaaac cagtggaaaa aaattaagga gacgatacgg atgcttgata
      721 tagtaccatc aaatacacat cggagtggta gcttaataaa ttttgctgcg atttttgctt
      781 gcgcatcggt aattctagca tctccagttg ttgtggatgc aagttctact ccgaaaacta
      841 aaaatgataa tcaacttgta attactacaa aaaatgagat taacacaatt tcaagtaatg
      901 atggcaaaat ttttgatgtg ataaatacgg ttttaaaaag aaaagctgaa atcaatataa
      961 aatatgatga agatttaaac ttgtatttct ttgttatcaa aacaacatct gaattgtttt
     1021 cctcagatta cgatgttttg gatactctcg ataatgtatt atctgactat aaatatatgg
     1081 ggaaatctgt agtagcaact ttgggggaat aaaatgtttg actttaatga atatttatct
     1141 atttccaaac aaattgaatc agatgataaa tataattcta aagaatctta tagaagaact
     1201 gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt gaaagaaaat
     1261 tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt ttggaatttg
     1321 ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta tagaatgtta
     1381 gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac agatatggcg
     1441 ctgatgaatc gagaagcaga aaaaataata aacaaactca cctaatgaat ttcaagcgag
     1501 tttgtttgtt atttttttat ttaatctttg tatctttctg gatcaacgaa agtatacttt
     1561 atatagtcat aacgccgatg atcgctacgt gcgtccggca cgtcagtcac gatatcaaac
     1621 aaaaagtata cacccttctt cattctagtt ttcgcagcag gaattttgaa atagttctta
     1681 ttagaatagt agagattgat taataagcta tcttcgattg ctaaaaagaa aacttctgaa
     1741 ttccatactt tataaaaatc tttgataaat ctattcgaag ggtcaaattt aaaccataat
     1801 tgtgtctcat taaaaagcat aaccattact ccgatctgtt tttaaaatta gtttctacct
     1861 ctaatatata tcgagttttt attttgcctt cagagaatac tgtttctttt tttgcagtta
     1921 caggttgttt attttcggaa aaagctaata tagctaagat tgaaacatcc atctggaatt
     1981 tatctttttt actgctttga tcataaaagt ctgcatattc atcactgata ttttttctaa
     2041 taaattcttc catcataaaa atcacctcaa aacgattata cgaacttacg ttcttgttgt
     2101 aaagcgatat ttgaggggca aaaaaggggc ataatttgac tgatattaag ttagctattg
     2161 atatatgaat gacatacaaa aatataaaat cttttaaaaa tgcttatata tcaatgtttt
     2221 tgccattctt ttatatatct gttatatgtc aaaaaaatgt gttcaatttc aatttgtatt
     2281 tgaa
//
LOCUS       DAFLWZ010000172         2265 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000172 DAFLWZ010000000
VERSION     DAFLWZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.181"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(491..1783)
                     /locus_tag="L1V38_002938"
     CDS             complement(491..1783)
                     /locus_tag="L1V38_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1317402.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2057..>2265)
                     /locus_tag="L1V38_002939"
     CDS             complement(2057..>2265)
                     /locus_tag="L1V38_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317403.1"
                     /translation="NIVIFTDWLGVLFSNLIPILIIGICGIILSILELFESRNTMNRI
                     FACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          742 a          428 c          357 g          738 t
ORIGIN      
        1 atattataaa ttcacatgat tatcgaattt tattaagtta gtttttcttg taaatctctg
       61 ttcccaatga aactcgagac acttatttta aagaggaaac aatgtggtat ttaaatagcc
      121 ctcttgtatg ggctactctg tgatacttat tagccattaa actattttac ccacatagca
      181 tatattttga aatcgttcat tccgtaaatt caactaaata tgcctaaaaa aataaaaaat
      241 ctaagataga ataagattta ttcagtctta gatggattta tagcaacttt ttcgtaacaa
      301 ctttaaaaaa tacgaaaaga aagagctgtt ttactctgac tacgttgcta aattgtcgtt
      361 taatcattca tttaaaccaa atcttttttt atagaattcg ttttaatcct cctgaatcca
      421 aaaactatga aaaccgtaat taaatagtta agagttttta accaccataa ttctctcggc
      481 tattttgaaa tcagataaat tttgatcgga cacatagttg aataaaccta ccgttgttac
      541 ggaaggtaaa tcgcatactt ttcattctag aggagaaggt ctcgttgatc attaactgat
      601 taagcaccat agcccagttt tgaattcgac cacctgacca cttcgcgtgt aattctttcg
      661 tgcgtaaata aagtagtttt aggagtgcat tctcattaga gaacgctcct ttttttgtga
      721 cttttctgaa gctggagtgg acactttcaa ccgcattggt agtgtacata atttttcgaa
      781 tggcactacc ataatcaaat agttgttcaa catgtgcaaa gttccgtttc cagacatcta
      841 cagcaccaga ataatgagac caccgatttt gaaaactgtc aaaagcagca tgtgcagcgt
      901 ttagagaaga agcaccgtag aactttttca tatctcggca gacttcctta tagtccttac
      961 ttggaatata gcgcaatgca tttcgaacaa gatgaacaat acagcgctga acaattaccg
     1021 atggaaagat cgcttttgcg ccttcttcga ggccagaaac accgtccatc gaaatgaaaa
     1081 agacatcttc gacaccacgt gctttcagtt catcaaatac ttgcatccag cgatttttag
     1141 attctgtttg atttaaccat aatcctaaaa tctccttatt tcctttgaga tcatagccaa
     1201 gaatggtgta tacagcatat tctttggctt cataattttc tcgtaaagta acatacatac
     1261 aatcaacgaa tagaaaggca taacactttg ctagggggcg ggcttgccat tcttccaatt
     1321 caggaaggac agcgtcagtg atatctgaaa tcatttcatg ggaaatatca aagccataaa
     1381 tagcttcgac ggttgcggca atatctcgtt gactcattcc tcgtgcatac atggaaagaa
     1441 ccttcccttc gatgtcggag acatctcgtt ttctcttagg aattaactct ggttcaaagg
     1501 aagcttcccg gtctctagga acatcaatag ctacttcacc aaaactggtt ttaagcgttt
     1561 tagttccata gccatttcga cggttatcgt gttccttagg ctctttagaa tgggcatcat
     1621 aacctaaatg attattcaat tctccttgaa gcattttttc aaaaaggggc ccaaacacat
     1681 ctttcaaagc atcttgcatg tcatcgacag attcaggttg ataggcattc agaatggatt
     1741 cagctaactt ttcggcatca ggatttcttt tctttctagc catcgtgtaa tcacctcttg
     1801 atcttattgt agaaaaagaa aaaccgcgaa gcaaccacct gcctaggatt aatggttact
     1861 tacacggttt atattacact ctcatcatta aaaaagtatc tttcgatatt actaaacaat
     1921 gaaattatct atttgaaatt taaatctgat aatatattga gtgttccaat gagggctttg
     1981 atcctattat ccatatcttt ttcagtttta atattgatac acattataag aaaaagaaac
     2041 ttttggttaa tttatttcat cccagtgcaa aatataaaaa agtaaaatag accataggca
     2101 atagattaac aattaatata atacaagcaa atattctatt cattgtattt ctgctttcaa
     2161 aaagttctaa tattgaaagt ataattccac aaatgcctat aataagtatg ggaataagat
     2221 tagaaaataa caccccgagc caatctgtga aaattactat attta
//
LOCUS       DAFLWZ010000173         2215 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000173 DAFLWZ010000000
VERSION     DAFLWZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.182"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            273..1196
                     /gene="truB"
                     /locus_tag="L1V38_002940"
     CDS             273..1196
                     /gene="truB"
                     /locus_tag="L1V38_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBN1317404.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1200..2141
                     /gene="ribF"
                     /locus_tag="L1V38_002941"
     CDS             1200..2141
                     /gene="ribF"
                     /locus_tag="L1V38_002941"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBN1317405.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
BASE COUNT          780 a          362 c          479 g          594 t
ORIGIN      
        1 ccagtctttt ttttcgtttt tgggaagtga aaaccaaact atttacctgt aagccaccca
       61 taaatccaat caaatggtgc aaagaaaaaa tcttccattc tattccctcc tttaaaaaag
      121 cataacatga tttctattta cgtgagcatg aattttgtta cgtttttatt gccgaaaaat
      181 aaaaaccgtt cattatgatg tcaaattcgt cagtaattga tgcaatgtgt tataataatt
      241 cagttaaatc aaaaatgaaa tggagaaaag acatggacgg gttattacct ttatggaaag
      301 aacgcggaat gacaagtcat gattgcgtat tcaaattaag aaaaatctta catacgaaaa
      361 aaatcggaca tgggggtacg cttgacccag acgtagacgg tgtgttgccc atttgtattg
      421 gaaaagccac aaaagttatc gaatatttga cagattctgg gaaaatctat gtaggcgaga
      481 taactctagg tttcagtaca acgacggaag atcgatccgg agaacgggta gaaacaaaac
      541 cagtagatat gtctttatct gaaaaaaaaa tagatgaagt gatggcttca tttattggtg
      601 agatcaccca gataccacca atgtactcag cggtaaaagt caacggtaag cggttatatg
      661 aatatgcccg caataatgaa acagtggagc gtcctgttag aaaggctcag atttaccgtt
      721 ttatccggac aagtgaattg acaagagacg aagtgacagg aaccatttct tggcgcttcg
      781 aagtagaatg cgggaaagga acctatgtcc gcacattagc tgtagataca ggcaagaaac
      841 ttggttaccc tgcgcacatg tctgatctga cccgaacagc aagtgccggt atgtcccaga
      901 aggatgctct gacattagaa gaagtagctc aagctgtgaa aaatgggaca atcgatgatt
      961 gtttgctgcc aatagaaaaa ggagtggaac ggttcaaacg agtagatatt actgatgaag
     1021 tatggcagaa agtaaaaaac ggtatgagac ttgattatac tgtatttgcg ctcccagaaa
     1081 tgccgtcaga agaaattgct ttgttttata aaggaaaagt tgtcagtatt tatcagccaa
     1141 acccgaaaga aaaaaacaaa ttaaaaccta gtaaagtatt gagaaatgag gaataacgaa
     1201 tgaatatcat caagatcaga catccttacc aatcagaaca aattccagaa gacgatgtcg
     1261 ttttagtgct gggatttttc gacggcgtgc atatcggaca ccagaaagtc ataaagacag
     1321 gtatggaaat tgcacaaaaa gaaggattga aattagcatt gatgactttc aatcagcatc
     1381 catctattgt ctttaaaaag atcgatccta gcagcgtgaa atatttgact agccttaagc
     1441 aaaaagaaga aaaaatggcc gctttgggta tagattattt atatgaagtt gattttactt
     1501 cttcttttgc tcatttagca ccgcaggaat ttgttgatca atacatcgta gggttacatg
     1561 caaaatatgc tgtttccggt tttgattata cgtatggacc aaaagacatt gcagatgtcg
     1621 ctcattttcc tgaatatgcc aaaggaagat tcaaaatcgt cacagtttct aaagaagaag
     1681 aacaaggtga aaaaatcagc tctacccgta ttcgtggatt actagacagc ggacaagtaa
     1741 aagaagcagc aaaactatta ggttgcacat atgaggtaga aggggtagtt gtccatggcg
     1801 atgcacgagg cagactacta ggattcccta cagcaaatgt caaagtaaag agcacggttc
     1861 atttgcctaa agaaggtgtt tatgtgtcgg aaataaaaat tggggaaaca tggtatccag
     1921 ccatgggttc aattggacat aatgatacat tcggtgaagg acgggagctg actgtagagt
     1981 tgtatatttt ggactttaat caagatatct atggtgaaca tgtcgcggta cgctggaatc
     2041 aatttttaag agatcaagtg aaattttcta gtgtagagga attgattgaa caactcaagg
     2101 aggatgaaca agcaacagct gaatattttt ctcagcaata aaacattatg cataaaatct
     2161 cttgtttatg tataactagc aattacaata aaatgggtga taaataagcc cagga
//
LOCUS       DAFLWZ010000174         2163 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000174 DAFLWZ010000000
VERSION     DAFLWZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.183"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..197
                     /locus_tag="L1V38_002942"
     CDS             <1..197
                     /locus_tag="L1V38_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1317406.1"
                     /translation="NNLIEQDHRPIKRRNKFYRSLRTASSTIKGMETIRGIYKKNRRN
                     GTLFGFSVSTEIKVLMGIPA"
     gene            280..897
                     /locus_tag="L1V38_002943"
     CDS             280..897
                     /locus_tag="L1V38_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317407.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1061..1393
                     /locus_tag="L1V38_002944"
     CDS             1061..1393
                     /locus_tag="L1V38_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317408.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1717..1878
                     /locus_tag="L1V38_002945"
     CDS             1717..1878
                     /locus_tag="L1V38_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBN1317409.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1910..2163
                     /locus_tag="L1V38_002946"
                     /pseudo
     CDS             1910..2163
                     /locus_tag="L1V38_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          775 a          279 c          434 g          675 t
ORIGIN      
        1 tgaacaattt aatagaacaa gaccatcgac ctattaagcg acggaataaa ttttatcgaa
       61 gtctccggac tgcctcatcc acgattaagg ggatggagac cattcgagga atatataaaa
      121 agaaccgaag aaatggaacg ctcttcggct tttcggtgtc tactgagatc aaggtattaa
      181 tgggaatacc agcctaagat atttggagtt cagagagggc gcgtttgatt ttcaaacttc
      241 gcaacagaac cattatttta aagtgggagg aaaattgttt tgtggatatt taaacaagaa
      301 atctttgcta aattatttag tttagatgga ttaggttggg gaatcttatt ttttattttt
      361 ttatttttag gatctatgtg gatctggttt gttgataaaa aaaattctta tgagaaagta
      421 atagtgaaaa aaatgaatcg aaatgaattc gatgattttt caaaggaaca tagagttgaa
      481 ttgtacgata gtcatgaaat taacagtact tctccatctt attattgggt atttggttgc
      541 gaagaaaaac cattggagat taaattgttg aaaatgcttg aaaatcctcc agtcattgaa
      601 gatttttctg caaaaaacgt tgaaaaacag atgtttgaac aggtacaaat aagaggtcaa
      661 aacaaaattt cattagaacc agatgaatat gcagcctttt ttttagaaac aaattcaggt
      721 acttcaatgc ctgttttcaa agttaaatta aaaatgaatg gtcgtttatg cacttatgat
      781 cttgttgcaa atatgcgcta tggttctact ggtgatagac gtactatttt aaaatttgag
      841 caaaccttta gaagtttttt gaaaaataga gtatcccaaa tttttaattt ggattgaaaa
      901 aattaaaaat ttggccaaaa atactacagt tttttagagc aatcatctta tgatgattgc
      961 tctttttttg ttgtttttgt gtcattcgtt gttcaaatcc tctattcgta aaataaatat
     1021 tttaaactag aaatatgcct tatttttagg aggaatcaaa atgaacaata gagaaatatt
     1081 ggcaaaagaa atggcggatt tgaaagcaaa agaagcgaag attagagcga aacgaaaaca
     1141 gattagacag aaagaaatga tttctttagc gaaattatat tgtaaaaagg aaggctttaa
     1201 gacacctgct gaagcattag attttttgga atcaaataaa agaaatcatt cagtaaatga
     1261 tgaggtttta gtatcgctaa gaaaatttgc agatggatta gtttggcaag aaaatggtgc
     1321 atattggcgt acgaatgatg ttaagggttt gactcaattt atggcacaat ttcgttcaga
     1381 aaatgtgaac taaattgagg aggggttgaa gtgaaaagca atacttttca cttttggttt
     1441 tttgcggaat aaaaattgtg aaaacaatga cgcaaaaagc caatggtttt gaacgaaaaa
     1501 aggacgtaaa aaaggaatgc gaaggcagtc gtttttcgtt cgctttttcg tttgagagaa
     1561 acggagtttc tcatcggctg ttaagccgat atagccctcg gcagagctta cagactttac
     1621 gcagtataag tctagtaagt tataccttac atggaggttt ttccgaattt agcttgtgat
     1681 tctcgcaata attttaacga aaggaagtac acagttatgg cctatatggt ggcacgaaca
     1741 caaaagcata aagttgggtc gttaaatgga cttcaaaatc atgtagatcg taaaacgaaa
     1801 aatcatacga ataaagacat tgatattacg aaaagtggtt ctgttgcaaa gttttccaaa
     1861 aaatctattt tagtgtaaaa ttgagaaaaa agacagagag gatagagtaa tgaatcattt
     1921 taaaggcaaa caattcaaaa aatgacgtca ttattgtcgc tgttagttac tacctgcgtt
     1981 acaatctaag ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc
     2041 atactacgat ttatcgttgg gtgcaagagt acagcaaagt cctcgattat ctttggaaga
     2101 agaaaaatag acaatccttc tattcatgga aaatggacga aacctatatc aaaattaagg
     2161 gac
//
LOCUS       DAFLWZ010000175         2129 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000175 DAFLWZ010000000
VERSION     DAFLWZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.184"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            742..1074
                     /locus_tag="L1V38_002947"
     CDS             742..1074
                     /locus_tag="L1V38_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBN1317410.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1693..2034
                     /locus_tag="L1V38_002948"
     CDS             1693..2034
                     /locus_tag="L1V38_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBN1317411.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          752 a          280 c          438 g          659 t
ORIGIN      
        1 attacaaaat aatagctatt ttaatagaat ttataagtta aaatattatg ataaaaatca
       61 caaacgtagc cttttacgtc ataagtgtta aaagaaataa ttaatttcaa atatagaaaa
      121 gggaacgtat gtttgcatac tccttttttt tgagttataa taatacgcga agagagataa
      181 tttcattatt taaacaagct aaaaatcttg atattacttc ttttcaggca atacgaatat
      241 tattcgctta cattttttgt ataaatttaa ttgtctgcta tgcttgtgat gaattgattt
      301 tcgttttgca cttttggatg ataaatttgg acaattgaaa atacaaaaaa aagaaaggcg
      361 gtatgaactc ggaaggctgg taaccttcgt cagcgttcat acacggcatt aagatttggc
      421 ccttaatgcg ttaacctttc agtgttacgg tattacccgc aatggattta gtataacaga
      481 tattcaaaag tgataccact ttttttggct gtgttaaggt taaaaatacg tgatattacg
      541 atgaatctat gcctaagcat aatgttataa aaatgtccgt gtggctcttt gccgtatgac
      601 gaacgctgaa attagaggga acgcatgttt ggatgcgttc cctctttttt gtttgtcatg
      661 aacgaaaatc aattctctat ttttgaaaaa taacaagaaa aacttgttaa aaatatttaa
      721 agaaattggg tggtttattt tatgtcatat acaggaattt tgagtctcaa agatatttgt
      781 cactacggta aacggtgtac cgctacagag aaaatcacga agaaactatc aactggccaa
      841 agtaaaaccg ttgtgcagtg taagaaatat ataatccaga aagacaaagt ctcagaggaa
      901 atgatttatt acattgggaa acaaaagcaa ataattttaa aagatcctat ccccttaaaa
      961 gagctatatc caacaatcaa acatgtttat gaccaaaacg gtgtactgat tggtcgaaga
     1021 aaaaatggag tcttgcgttg taccgcaaaa gggatggggc gtttgatcgg ctgaattgat
     1081 cattctcata acttgtattt tatcgttttt cgcttgcttg aaaatattgt cgagacttct
     1141 aaaggaactt agagtcacta gaaaaataag gagtagactt gatctatcaa caattccctt
     1201 cggggagtga cggggtaggt tttaacgatt ggtaacgtaa aaaattggtc aatcgagtaa
     1261 atgcgcttgt ttggatagtg gtgaaatgaa tttgtgtaaa taataagcgc agagtaaaca
     1321 agagggaatt tagaagttag acaagttaga atagcgtcta gattaatcat gagcagctac
     1381 taagggatct agactttgac gcaaactcat ggaataagga gtaggtcttc tcgtaatggg
     1441 gaggacgcac aagaaattgt gtcgtgtgct gcagtacatg tagatacttg cgaggacgtt
     1501 gattattgga tcaatcgagc atttaccgct gtctactagg gtttctcgtt tcggacgcca
     1561 taaacgagtc gaaatttttt atgtattttt aagtaaacga aaaacgataa aatatgaaca
     1621 agtcctgaat aaagtgaaaa aattgatata aaacatagag aaaatgaaat ttacgtaatg
     1681 gaggaatgac aaatgaaaaa ttatgatccg aatatacgat tgggcacaca tactattaag
     1741 gtttctttcc aacgttggga ttacaaagga tttgtgacgt ttagaagggg cggaaattgt
     1801 aaaggattag atgttttagc attagacgag gatgatttat acgatcaaac attgactgat
     1861 aatccaattg gattcggctt gctacctgaa gatgatgaag gtaatgaatg gtttaaaatg
     1921 acgcttatga atgataatgg agacgaatta tctgttgaag atacttggtc atatttgagt
     1981 gattatattg tcagctttga aatcattgaa tttgtagcgg ataaagaaga ataaaaactg
     2041 gaggaataaa ttttacagat aaaggcttag aaggagtcac gacgattaat aaaaaggtag
     2101 tattacctta ggcattgagt aaggaattt
//
LOCUS       DAFLWZ010000176         2077 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000176 DAFLWZ010000000
VERSION     DAFLWZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.185"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            170..841
                     /locus_tag="L1V38_002949"
     CDS             170..841
                     /locus_tag="L1V38_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1317412.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(1566..1901)
                     /locus_tag="L1V38_002950"
                     /pseudo
     CDS             complement(1566..1901)
                     /locus_tag="L1V38_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          767 a          321 c          261 g          728 t
ORIGIN      
        1 gaaaaataaa atactccttc tttttggact gattttatcg aaacttattt tttctttttt
       61 tcatgtattc ttttattttt ataactagtg tattacttca aaatttgata ttatatggca
      121 tgaacagaat taaaatatca gttaaaataa aagttaagga gcattgtgta tgacaattaa
      181 aactagtctc caaaatcaag cttaccaatc tattcgccga caaattatct atgctgactt
      241 agaacctgga aaaaaagtat cagaaaaaaa attagaagaa acactttcta ttggtcgtac
      301 accaatacgt gaagcactga ttcaactccg acaacaaggt cttgttgata caattcctca
      361 aagcggaaat tatatctcat taattgattt agattcggcc aaaaatgctc gatttgtcag
      421 agaacatttg gaacgacaaa ttatgttaga gtgttgtgcc aaaatgaata accaaaaaaa
      481 acggatttta gaaactataa tttcagaaca agaaaaagct gttagtcaaa aaaatgctcg
      541 tagttttttt cataatgata atttattcca taaagcttgt tttgaaattg cagagcgaga
      601 agaagtatgg caatggttag aaaataacaa tacacactta gaacgatttc gatggctacg
      661 agtaaaaacg gaaggattaa agtgggaaaa aattatggaa caacattatc aactatttga
      721 ggcattaaca aaacaagatc cagaagaagc taactttcta acatcgttgc atcttcattt
      781 aatgcttaat gagcaaaata ttgttttagc tactcatcca aaatatttca aaaatatata
      841 acttttaact ctttttaaat taaatggttg ttctgatcag aaaaatatcg cttgttttct
      901 tattatgtaa tatatttcat aaactattct gcataacaac tattgtttgt actttttaca
      961 ttggataact aattatgact gctgataact tttgatatta aactagtatc tccaatacaa
     1021 ataaaaaata gatatcttgt tcatcaaaat tagttcgtgg atacttacct tcatttacat
     1081 cattcagcgg tttcccattt tcttttattc tattatttca ttttctaata gacttggctt
     1141 catttcgcaa tacttttttt caataggcat caaattggtg ttgtttagat atttagttgt
     1201 agttttgtga catgataagt atgctccttt ttctcttttc cactaataca acgatcaaag
     1261 ggtgcttttt tcaaaaaact agaaaaatca aaataagatt cgtattttga ttctatatat
     1321 cctgtttcaa ctacatctta tatttcacaa tagaataaat agccttttgc atagctgctt
     1381 aacttataag aaattgcaat ttacttcttc aaagtgaaaa cgaatatgag taaaataaaa
     1441 ttattcttct tacagataat taaaaatagc gcgtaacaaa aatcggcatt caatcacata
     1501 attaggattg atgccgatta cttatattct acgtatagtt ttagtattct tattttttat
     1561 caccagtaac caattgagaa cagccctaaa gcagaatagt cttttatctc aaaacgctta
     1621 atttcaggct taggaatatg aataatcttt tgagtatatt ctttctcttt taatcttact
     1681 gaagaaatac cactgcctat cttttttaca aatatttcat ttggtgtaca gactaataaa
     1741 acaatatttg taatcaatcc ttgcactaaa gaattaaaag gaagactatt taaaacaggg
     1801 tgtgcataac tataacatgt gaagtagtta ttttgaactt taacttttaa aaactttaaa
     1861 aataatctta tttgttcttc taaacaatca tctatactca tataatcact ccactaatta
     1921 atctccccaa aaagacacag cattaagaga tataccaaca caacagtgca aataactcta
     1981 catcttcctt cgcaacctta tttcaataaa ccataaaaat tattttttaa tagaaactga
     2041 aaattaaaac tagaaaaagt agttttaccg aatgtaa
//
LOCUS       DAFLWZ010000177         2063 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000177 DAFLWZ010000000
VERSION     DAFLWZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.186"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..425)
                     /locus_tag="L1V38_002951"
     CDS             complement(<1..425)
                     /locus_tag="L1V38_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1317413.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(534..1565)
                     /locus_tag="L1V38_002952"
     CDS             complement(534..1565)
                     /locus_tag="L1V38_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317414.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          637 a          333 c          356 g          737 t
ORIGIN      
        1 ggaatctgtt ttgattttgt tccatttgaa atttctctca ctcgcttttt tgtctcatca
       61 tcaaataaaa tgaaagggtc ttctaaacga tcgataaata cttccattgt tgttgttggt
      121 agatgataag aagtcatgac aggcactgca ccaaggtaag acacagaaac agctagaagg
      181 tatgtgtcaa aagcggaact cttataaata ataactttgt ctccggattt cactccaaga
      241 tgagccaatt gataagcccg tttcaacaca ctttcgcagc attttttgta agttgtttca
      301 agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga taatcggggt ctcggaaaag
      361 ttagctgcag cttcttgaaa attcgtaaat aagttcaaag gggaatacgt tatggtctcc
      421 atcattcaca ctccattatc ttttgttaag taatatacaa attcaagata atcgtaacat
      481 aatcctttat ataataacat agtttattgt gaaaaaaaga tcatacattt gttttatatg
      541 gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa aatcaaccat cttttcccag
      601 atatcttgaa aagaatggga tgagaggtat cgattaccac ataaataatt taccgcgtca
      661 gcatcatcta aatatagttc tgcataataa cgatatgttt ttctgcatag ttctggcgat
      721 acgtttttat atactgtaat tttgctcaaa atttggcgaa tagtccgagg agaaatttgc
      781 tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg tattttgtgc tgttaactta
      841 aaatagttct ccagaaatgg catcgcttct tttggtattg gtactttatt cagtctgttt
      901 tcttttctat tcagattaag aatctgcttg gtcaaagata catctttacg tttaagttct
      961 actacttcat ggatctttaa tccgcaatac agaagaatgg cagtaattgc aaggttcctc
     1021 ggtctattct tttcttcaaa gctagcttct ctgcttgttt gaaagccttc aatcgggata
     1081 aacaaatgct caaaatcttt gaaaagttct gcatcgatat atcgcggagc tgctttggtt
     1141 gtttccggta aacttgtacc caaaagagaa atctcttctt caatcagtcc tttttgatac
     1201 aaaaatcgta aaaaatgatt taatgaatat tgcttccttg aaatcccgta atagctattt
     1261 tcaaacaatt gctccgtttc ttggttcgct gtagtttgga acgaacgagt atgtcgatag
     1321 attttagcta agaaattctg ataatcttgt ttttctaaat ggataatcag ctgatcatcc
     1381 acttcttcag aaaatacttt tctcaaataa tcagtaaaca gatgaaaatc ttttgcgtat
     1441 tcatagcgac tgcctaatga aagggaagaa cgattttctt ctaaaaactg ttgaaagacg
     1501 gaagggagca agtgtgtacg ttgctttaac ttttcttgca gttgttttct agttttgctg
     1561 tccattacaa attccctcca atagtgttca ttttctatat tttaccgcat ttcatcaaat
     1621 gaagatagac agtttgtctt gatcttagga agcaaatttt taactaagta ctagctaaaa
     1681 gatatgaagt aagaagatac atttttagtt attttattag tgcagtcatt cttttgatct
     1741 tttaattgat ttatcctctt tttagctatg tggttacttc atgagcaatg aaatggattt
     1801 ggttcgttct aatggcagga ggctctttct tttatttccg aaaaattaga aaacattttt
     1861 tcagaatcga ttggctctcc atttattcaa taatggtttg tctaacgata ttgttgggat
     1921 aattcttaaa gaagtattag aaatagttgg tacttcatta ctttacatga agatttattc
     1981 tatggtagga gcaattatat tgagaattaa tcctttttta tataagttgt ttgcttattg
     2041 atggattgga taaattaaac cat
//
LOCUS       DAFLWZ010000178         2060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000178 DAFLWZ010000000
VERSION     DAFLWZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.187"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            274..840
                     /gene="amaP"
                     /locus_tag="L1V38_002953"
     CDS             274..840
                     /gene="amaP"
                     /locus_tag="L1V38_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1317415.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            853..1041
                     /locus_tag="L1V38_002954"
     CDS             853..1041
                     /locus_tag="L1V38_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1317416.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1054..1611
                     /locus_tag="L1V38_002955"
     CDS             1054..1611
                     /locus_tag="L1V38_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1317417.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1643..1885
                     /locus_tag="L1V38_002956"
     CDS             1643..1885
                     /locus_tag="L1V38_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1317418.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          762 a          314 c          414 g          570 t
ORIGIN      
        1 aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt aatcttgaat
       61 aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa gcaattgtta
      121 tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg gtagcgcttt
      181 atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt agagttattt
      241 acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa aataatcggt
      301 gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat caatgcgccg
      361 tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa ttactacatg
      421 caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat catcttgcta
      481 gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga agatggcaaa
      541 ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca cgaagaagag
      601 ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca tatccatgtc
      661 aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt gatgcaagat
      721 atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt ggcagtcaca
      781 tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg agtggaatag
      841 gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat ctttgggggt
      901 cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac attgttgatc
      961 ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc aggaatagtt
     1021 gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat gaatacaaca
     1081 aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg tgaattgact
     1141 tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt agatggtcta
     1201 ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa cacagataac
     1261 gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga tctagatgtg
     1321 atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga attgatcagt
     1381 actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa tgttgcagac
     1441 atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa agtaacagaa
     1501 gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa atctgctgta
     1561 ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata agaagtaaga
     1621 agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg gcggtatcat
     1681 tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca tcgcaaacat
     1741 cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt ggggaccaac
     1801 aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag tattagtcgt
     1861 ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg aaatgaagaa
     1921 caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt tatatgaagt
     1981 attctttatt ccttatgaaa aaatatcttt aaaaataaaa aaagacgaaa ataaacggtt
     2041 ttctataaaa agaagaccgt
//
LOCUS       DAFLWZ010000179         2053 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000179 DAFLWZ010000000
VERSION     DAFLWZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.188"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..122)
                     /locus_tag="L1V38_002957"
     CDS             complement(<1..122)
                     /locus_tag="L1V38_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1317419.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1V38_002958"
     CDS             complement(133..330)
                     /locus_tag="L1V38_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1317420.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1V38_002959"
     CDS             complement(353..646)
                     /locus_tag="L1V38_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317421.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1V38_002960"
     CDS             complement(683..820)
                     /locus_tag="L1V38_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1317422.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1V38_002961"
     CDS             complement(822..1268)
                     /locus_tag="L1V38_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317423.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(1265..1414)
                     /locus_tag="L1V38_002962"
     CDS             complement(1265..1414)
                     /locus_tag="L1V38_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317424.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            complement(1431..>2053)
                     /locus_tag="L1V38_002963"
     CDS             complement(1431..>2053)
                     /locus_tag="L1V38_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317425.1"
                     /translation="TRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKI
                     SEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERI
                     NDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPIS
                     FEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
BASE COUNT          558 a          424 c          323 g          748 t
ORIGIN      
        1 gaactacctt cgtttacacc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 atcggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacaca ccagtgataa cacctaaaaa
      181 tgttgctgct gcattgatag tcagaactgc catatctgtt ccattccatc catatgcttt
      241 gcctaatgtg gctactaata cagataaagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 acctttctct aaataaagtt ttaatttgtt gtgtgtgttc taccaatttt tctgcatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtaattga tcctgcgatt gttccccatt cccctaaatt gatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctttcttc tttgctaatg attttatctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgaa atgtctttgc tattttgtaa cgaagcaagc
      901 atcatttttg aattgatttg tgctaaacta tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaattg ctacatcgct tagcatgagt ttggcattga tctgttttaa atcgccgttc
     1021 tcattttcta acgactcata cattgctttg agattgttta aatcgttgtg atctagtgcg
     1081 ttcgctaaaa taatccattg attcaattta ggatcaaaca tttgatcagc gattgttaac
     1141 ggttcgccat cagcacgaat tccttcaagc ggtggctgat ctgtgtaagg aacggataca
     1201 agcatgtcgt ccaatacttt tcctgcgtac tctccgccag tacgtccata tttccaaatg
     1261 tttttcattt atttccctcc cagtaattga atttcggttt ccaatttaga atcggtggtt
     1321 cgacttctgt gcattcttcc ggtaaatgtt cttcatcatt cacaatgatt tgctcgaatc
     1381 cgtaaggttc aattggtcta tatgctgcct tcatatcgat tcacgctttt ctaaatcgtg
     1441 taagtaattg caaaggtata atccgatcca taacttgagt ttcttcgcca tttaatggct
     1501 ccatctgcac caatagataa ctgagcactg ttcaaagtag aacggtctat cgagccaacc
     1561 agttgctcaa aactaattgg tggccgatag ccttctggaa ttgttagtat cgttgaatca
     1621 tttccaccac tgctttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca
     1681 cgataaagct ttgctgatcc ggtattcccg tttgtaactg ttaatgtggt agtagctgta
     1741 tcattaatgc gttcatcgat cttattgtct aattcatcta tagcagtcgc attagcattc
     1801 gcttttgttt gagcatcctt agctgtggtg tctacttcat taattgaagc agtcaactgc
     1861 gaattaatct ccgatacttt cccatcggta taattgtttg ctttaccagt aatttcagaa
     1921 attttaatat ctgtggccaa attatcttcg acatattctg gtgctagatc ccaaacataa
     1981 tcttttggat tgtttgaatc acgcatacca gtaccacgat atttatactc actaatattc
     2041 ggggttcgag tat
//
LOCUS       DAFLWZ010000180         1999 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000180 DAFLWZ010000000
VERSION     DAFLWZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.189"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            76..1245
                     /locus_tag="L1V38_002964"
     CDS             76..1245
                     /locus_tag="L1V38_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1317426.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(1512..>1999)
                     /locus_tag="L1V38_002965"
     CDS             complement(1512..>1999)
                     /locus_tag="L1V38_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317427.1"
                     /translation="LNYSSVVNMVKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKD
                     QLLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNA
                     TVLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSH
                     E"
BASE COUNT          709 a          338 c          303 g          649 t
ORIGIN      
        1 ataaatgtta tcaagataca agctatttta gctttattct ttctgtaaaa aagaaaggag
       61 actaaataaa ctattatgaa aaaaggaaaa catgctaaaa aaagaaaata ttcattttta
      121 atgatcgttg tcgtgttgtt tagccttagt gcgttctcta caggaactat tcttggatgg
      181 caattttaca ataatgaaca ctctcagata gttgcccatg ctcaatcagc tcaaaaaaag
      241 ttgatactga ctaccaatga acaacagctc gttgaaaaaa tcgatcaact attaagaaaa
      301 aatgattata ttggctcaat ttacgtaaag aaaaataatc gcatcatcat ggaaaaaggc
      361 tatggctatg cgaataaact cacgcaacaa ccaaatgatc cttctcttta ttatcagatt
      421 ggttcggttc aaaaagcatt gactactctt ttgattttaa aacaagtcga gcgtgggcac
      481 ctttctttag atactaagct ggctcaattc tatccacaaa ttgctggcag ccagcaaatt
      541 actatccgtg acttgctgta tatgcgctca ggcttgcacc gaactgcttc tccaaccata
      601 ccgatgactg atgaagaagt cgttcaattt gcgattcagc acttaaaatt tacagattat
      661 cagacctctc attatgattc attgaacttt accatattga ctggaatttt gatcaaatta
      721 acaaatcaac cgtatgaaaa attattgacc gatgatatca tcgaaccttt aggattacag
      781 catacaaaat tttatgacca agtcaaaaat tcatccaatc atgcactatc ctatcaaatg
      841 tctaaagagg atgattactt taaaccactg acagaatctg aaacagagat ccataacgaa
      901 ttagggactg gtaatatcag tatgtccgtc tatgatttaa atacgctgtt tacacaagtt
      961 ttatctggaa aactagtttc caaagactta ctcttctcat tatggcgtga aaatgcgaat
     1021 ggacatccat atagtggtgg ggtatatagc ggagataatt atatcctgtc gcaaggaaat
     1081 atcgactctt ttgatacatc tgctatattt agcaaagatt cacaggatgc tatcatcatg
     1141 gaaagcaata taaaagctga caaaactatc aaactgccta ctgctgatct aagaaaccaa
     1201 atctatgacc tgatggaagg aactactaag ttggcaaata gctgatatga tgaaaagata
     1261 gcaaatacta cttctttgaa tagcatttgc ttaaaaaaag tactcgacta aacgtaggaa
     1321 agagtgtggg acaaatctaa aaatcaattt ttgctacaga ctttaattcc aaataaacag
     1381 aacagaaaga ggtgttcttc tttctgttct gtccaaatta ttctaagatt tctctttacc
     1441 aacattattt gacaaagggc ctattaaatc taaaatagta tctttagatt gctaaaatat
     1501 gtgctagcaa atcattcatg gcttgttctt atttttaatt ttatgcaata aaaaagaaga
     1561 acaattagcg tgattataga aataaataat gagattttag aaaaaaatgt gtatgaatac
     1621 ctgattgtta ctttatttat tccactttca ctttttactg taacaaaagg acctccttgt
     1681 tttagtactg tagcattttt tgaattaaca gtaaccgtta atcctttata ccggaataca
     1741 ggtaaaacta ttgttttgcc ttttgaagat ttaaacgtaa atgtaatttc atctttattt
     1801 ggagaaaagc tactataaat aacttgacca tcttctgtaa cttgatggtt tttcaaaagc
     1861 aattgatctt ttttatagcc tataggtaca taatcaaaat tctcaaattc ttcaagttta
     1921 ttttccattt gttcattaga ataagttcct tgaaaattca tttctttcac catgttaact
     1981 actgatgaat aatttaaaa
//
LOCUS       DAFLWZ010000181         1885 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000181 DAFLWZ010000000
VERSION     DAFLWZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.190"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            943..1155
                     /locus_tag="L1V38_002966"
     CDS             943..1155
                     /locus_tag="L1V38_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317428.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1145..1540
                     /locus_tag="L1V38_002967"
     CDS             1145..1540
                     /locus_tag="L1V38_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317429.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            1633..>1885
                     /locus_tag="L1V38_002968"
     CDS             1633..>1885
                     /locus_tag="L1V38_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1317430.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKG"
BASE COUNT          669 a          273 c          319 g          624 t
ORIGIN      
        1 attgtttaat ggcacaaaca taaattatta tataattacg tattaattta tctagatcta
       61 ttaataatac tgatccctaa taggtgtaaa acagttataa gaaatgagta ctctagtatt
      121 tgtgttaccc gaataattac ttgattatat tggtttccca tataattgaa ggctgtccta
      181 atttttacct actatatgat cataattgat taactcttat atatttccga aaattatctt
      241 gaagatttct attggtatgg agaatatcca tttcattgcc aataaggata taaattctca
      301 aaataacaat cgatgtctgt attaaacaag cctagaatgg taaatctgat tcgccaaaac
      361 cattggattg tatcgatttg ctttacgcga acgccaccta cccattttat aaaaataaaa
      421 tgggcaaaag atctttcttt ttgtcataca aaaagaagaa aaaaaagaga cgattttctt
      481 cttccaaaat cgtccctctt ttttctaaaa ccatggatga acgaacaaaa aatctctcgt
      541 attttgtttg ttcatccact aaaaatatgc gaacagtatg gtttcattca atcctgttct
      601 tacaagtcaa aagcatcgaa tcgtccttgg acgattcaac aaaaaaagta gtcgtttttg
      661 gatgactact aagttctaaa cattcattac ccaaaatcaa tttggtctaa catcgtttct
      721 cgactggctt gatctaatcg gctcttgaca gggctttttc ttttctgttg atagcagata
      781 agaggaaata agaataagtg tgttcatgtg tcataaaaac agtaactaaa acattaaaat
      841 caaaatttat atggaaagct tccttgacat tttgtgctcg caggagtatt ataaaagcac
      901 gaaaggaaag taaactttcc attttttaga aaggagcatg ttgtgaaaaa tcgtttggaa
      961 gaattacgaa aacaaagagg aattaaacaa gaagatttag cttctgctct tgaagtatct
     1021 cgtcaaacaa taggttcttt agaaaatgga cgttataatc cctctattat attggcattt
     1081 aaaattgcaa ggtactttca aatgagcatt gaagaaattt ttatctatga ggaggaaagt
     1141 gaagatgaaa aataagggtc agatttggta tatcggttat attgtttcgt tgtttttgat
     1201 tgtgacaatt ttggttacag attttcctaa aatggtagat attggacttg ctattttatt
     1261 cagtgccgtt tttggcgttt ctcatgttca aattttgcat gataaaatga ttaaaaatga
     1321 tgcagactac aaaatcaatg ttatggacga acggaatatc ataatcaaag aaaaagcggg
     1381 aaatataaca aatatgttta acacaatact gttaggggtg gcaacagtta tatttatttg
     1441 tttagactac atcattccag ctattattgt cggaagtatc attgcaatcc agccgattat
     1501 tttaatcatt atcagtagtg tgcttgagaa aaaaatgtag aaataaaggt tcatacaaag
     1561 gttctgttgc aaagttttcc aaaaaatcta ttttagtgta aaattgagaa aaaagacaga
     1621 gaggacagag taatgaatca ttttaaaggc aaacaattca aaaaagacgt cattattgtc
     1681 gctgttggtt actacctgcg ttacaatcta agctatcgtg aagttcagga attgttatat
     1741 gatcgtggaa taaatgtttg tcatactacg atttatcgtt gggtacaaga gtacagcaaa
     1801 gtcctctatt atctttggaa gaagaaaaat agacaatcct tctattcatg gaaaatggac
     1861 gaaacctata tcaaaattaa gggac
//
LOCUS       DAFLWZ010000182         1838 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000182 DAFLWZ010000000
VERSION     DAFLWZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.191"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            195..392
                     /locus_tag="L1V38_002969"
     CDS             195..392
                     /locus_tag="L1V38_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317431.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            498..980
                     /locus_tag="L1V38_002970"
     CDS             498..980
                     /locus_tag="L1V38_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317432.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1038..1634)
                     /locus_tag="L1V38_002971"
     CDS             complement(1038..1634)
                     /locus_tag="L1V38_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1317433.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT          570 a          275 c          367 g          626 t
ORIGIN      
        1 taaggaatat gttttaattt tttgaaaaaa attcttctaa atacaacagc tgttttaatt
       61 gtgaaaacga aaacagtacg ctataatgcc tgtaaggttg atttttaact gtaaataaaa
      121 atcaatgagt taaatctcca aagaaatagc agtggtaatg tggagaaaag ttccagcagt
      181 ttaggaggat tttgatgacg gaagaaatga ttaatttagg agaacaatat gcatgcaaac
      241 caattggttt tacaaaaacg gtcattggtg aagttgtatc aaaaatgaca aactgcgccg
      301 tggtcaaagt tgcccaatgt gctgcagagg accaagaatt attagatgaa aaagcaagca
      361 tggttgttgc aaaatatgat acatttgaat aaagaaaaca attggacgtg cggcgtgctg
      421 caagtccaat ttctttgaga aggtaaatca gtattctttt cctattttct ggagaagaaa
      481 aagcgaggcg agttgtcatg gtaacattct ttacggttct attgttttta ttcgttgttg
      541 tgatgttttt atttctttgg ctggttcgaa aagaaattat ttatcggact gtgcgaaatc
      601 gatgggtcta cttggtgata cccttcttag tgtcactagt catttggtat acactcatca
      661 gtcatcctac agcagatgaa ttggcaaaag ggatcttgtc agcaatgatt tttattagtt
      721 ttttgttgga cagtagagga atcacagaag aaggacttgt tttgaatagc tttgacaaaa
      781 aaggtgttcc tttttctgag atcaataaaa ttgtattata tcagccaaaa ggttctaaaa
      841 tcgtaaaaat gaattttttc cgaaacggat ggcgaggacc gatgctgaaa ttttctgcat
      901 cattagaaga attagttcca tttttgtccc aacgcttaaa cgatgaggca gagattgata
      961 ttatgattga tccagaataa aaacagaggt tgcgacaaga tgtttgtcac aacctctgtt
     1021 ttttatttca aataaaatta tccaaatacg cggaagcgat cggcatcgtt catgtattct
     1081 ttttcctcag ccggtgtttc tggtgaaccg aatactaatt gcgaacgtag tttccagttt
     1141 gaagggatat tccattcttt tgcaactgct tcgtcaataa ctgggttgta atgttgcaag
     1201 tttgcgccca atcctttatc aactaatgct acccaagtat tagctgttgc gattccgttt
     1261 gattgttctg accaatctgg gaagttgtct gcatataatt caaattgttc ttgtagacct
     1321 tttaccacgt cagtatcttt gaagaataat actgtaccat aaccattttt gaaaccagct
     1381 aatttgtttt gtgtatttgg gaaagcttct gctggagtca atgggcgaag tgcttcttca
     1441 gtgatttccc aaagtttttc atgtgcatct ccgaaaagga taactgcgcg tgttgattga
     1501 gcattgaaag cagttgggct ttctttaatt gcttctttga tcaaagttgt taattcttca
     1561 ttagaaagtg aaacattacg tcctagatga tagattgaac ggcggttttt caaagtgtca
     1621 gtaaaagttg tcataataaa atttctcctt tgatttgcgt tttgcatttt tttaattgat
     1681 tacgaaatga agtatagcac cttacaaaaa gtaagtaaac agatatgctc acaaaaaata
     1741 agcgaagttc aaaaaacaat tttaataaga aaaatcgtta tgtaaggatt ttcttagtta
     1801 tcgctttcat tgttgtgttt taggaatttt tgcttatt
//
LOCUS       DAFLWZ010000183         1815 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000183 DAFLWZ010000000
VERSION     DAFLWZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.192"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..122)
                     /locus_tag="L1V38_002972"
     CDS             complement(<1..122)
                     /locus_tag="L1V38_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1317434.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1V38_002973"
     CDS             complement(133..330)
                     /locus_tag="L1V38_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1317435.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1V38_002974"
     CDS             complement(353..646)
                     /locus_tag="L1V38_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317436.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1V38_002975"
     CDS             complement(683..820)
                     /locus_tag="L1V38_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1317437.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1V38_002976"
     CDS             complement(822..1268)
                     /locus_tag="L1V38_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317438.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            complement(1271..>1815)
                     /locus_tag="L1V38_002977"
     CDS             complement(1271..>1815)
                     /locus_tag="L1V38_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317439.1"
                     /translation="TRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNDAVNV
                     YDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVIV
                     NGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPSGTSSVSKAMYVRKDLGTIITN
                     SEFAANEWFTFHGNYWVGEE"
BASE COUNT          505 a          382 c          272 g          656 t
ORIGIN      
        1 gagctacctt cgtttgggcc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 attggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacacg ccagtgataa cgcctaaaaa
      181 tgttgctact gcattgatag tgagtactgt catatctgtt ccattccatc catacgcttt
      241 gcctagtgtt gcaactaata cagatgcagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 atctttctct aaataaagtt ttgatttgtt gtgtgtgttc taccaatttt tctgtatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtgattga tcctgcgatt gttccccatt ctcctaaatt aatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctcttatc tttattaatg attttttctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgca atgtctttgc tattttggaa cgaagcaagc
      901 atcgtttttg aattgatttg tgctaaacca tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaatcg ctacatcgct tagcatgagt ttggcgttga gctgttttaa atcgccgttc
     1021 tcattttcta acgactcata catcgctttg agattgttta aatcgttgtg atctagtaca
     1081 ttcactaaaa caatccattg gttcagttta ggatcaaaca tctgatcagc aatcgttagt
     1141 ggttccccat cagcacgaat tccttcgagt ggtggaacat cggtaaatgg aacagtcata
     1201 accatatcat caagcacttg tccagcatac tctccacctg ttcgtccgta tttccaaata
     1261 tttttcattt ttattcctcc cctacccaat aattaccatg gaatgtaaac cattcatttg
     1321 cagcaaattc gctattcgta ataattgttc ctaagtcttt tcgcacgtac atcgcttttg
     1381 atacactact tgttcctgac ggacctgtaa gcatgccatg aacaattttt gcgacaaatt
     1441 catctgggac ttcatcatca agtggtacac caaaagcata agcttttttg aactttactg
     1501 taccatttac aataacttct tttccgtgtt taataaatgt tgcataccca tcgataaacg
     1561 attgactgtt gtctttagtt aatgtataaa cagtgcaatc attttcactg atcactttat
     1621 ctcctgctat ttgaatacca tcggcaaagt ttttcaaacc ttcaactctc tgaggatcat
     1681 acacattaac agcatcattc aagccttttt cagtatattc aggtgtgaca tcccaactgt
     1741 aatcattggg attgttactg tctttcaagc cttcaccaaa gtatttaaac tgactaatat
     1801 tcggggttcg tgtgt
//
LOCUS       DAFLWZ010000184         1761 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000184 DAFLWZ010000000
VERSION     DAFLWZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.193"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1299
                     /locus_tag="L1V38_002978"
     CDS             <1..1299
                     /locus_tag="L1V38_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317440.1"
                     /translation="STLSLISLSIKDATDRASKETFANITNSFSMEINRQVNPGTPRG
                     GGNVKGEDIKKISQTDSIDSYVKRINSVADLVDYDIIETQETLANQSPERAKNFKRTV
                     MLTGVNDSTKETKFVSEAYKLVEGKHLENEDKNKILMHKDLAEKNNLKVGDKIKIKSN
                     LFDADNEKGADETVEVEIKGLFDGHNSGVVSAAQELYENTLITDIHTAAKVYGNTEDT
                     AVYQDATFFVKGDKNLDSVIKDLGKLDINWREYNLIKSSSNYPALQQSISGIYSISNK
                     LFFGSLIFAGVVVSLLLFLWMNARKKEIAVLLSLGISKLEIFGQFLIEMVFISIPAFV
                     GSYFLAQYTADKLGNNILNKVTGDIAKQIAKQSASSQLGGGAEAEGFNKTLSSLDINV
                     LPKFMIYVVIFMSLVLLVSLIISSFNILRRNPKELLIDNN"
     gene            1429..>1761
                     /locus_tag="L1V38_002979"
     CDS             1429..>1761
                     /locus_tag="L1V38_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1317441.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT          674 a          231 c          322 g          534 t
ORIGIN      
        1 tcaactttaa gtctcattag tttatctatt aaagatgcta cggacagagc ttcaaaagaa
       61 acatttgcta atataacaaa tagtttttct atggagataa atagacaagt aaatccagga
      121 acacctagag gtgggggaaa tgtaaaaggt gaagatatta aaaagatatc tcaaacagat
      181 agtatagact cctatgtaaa aagaataaac agtgttgcag atttagttga ttatgatatt
      241 attgaaactc aagagactct tgcgaatcaa tcacctgaaa gagcaaagaa ttttaaaaga
      301 acagttatgt taactggggt taacgactca acaaaagaaa caaaatttgt atcagaagca
      361 tataaattag tagaaggaaa gcatttagaa aatgaagata aaaataaaat cttaatgcat
      421 aaagatttag ctgaaaaaaa taaccttaaa gttggagata agataaaaat aaaatctaat
      481 ttatttgatg ctgataatga gaaaggtgca gatgaaacag tagaagtaga aattaaaggt
      541 ctattcgatg ggcataatag cggtgtagta agtgcagcac aagaactata cgaaaataca
      601 ttaatcactg atattcatac agctgctaaa gtttatggta ataccgaaga tacagctgta
      661 taccaagatg caacattctt tgtaaaaggt gataagaatc ttgatagtgt aataaaagat
      721 cttgggaaat tagatataaa ttggagagaa tataatttga ttaaaagttc atcaaattac
      781 cctgcattac aacaatctat atcaggtatt tactcaattt caaataaatt attttttggc
      841 tcattaatat ttgcaggagt tgtagtttca ttattattat tcttatggat gaatgctaga
      901 aagaaagaaa tagcagtatt actatcatta ggtatatcaa aattagaaat ttttggtcaa
      961 ttcctaattg agatggtatt tatatcaatc cccgcattcg ttggttccta tttcttagct
     1021 caatatacag ctgacaagct tgggaataat atattgaata aggttactgg tgacatagct
     1081 aaacaaatag ctaaacaatc tgcatctagc caattaggtg gtggggcaga agctgaagga
     1141 tttaacaaga cattatcaag tttagatatc aatgtattac ctaaattcat gatttatgta
     1201 gttatattta tgagtttagt acttcttgta tcattgatta tttcttcatt caatatatta
     1261 agaaggaatc caaaagaatt attaattgac aataattaaa attttcggtg ctttttagca
     1321 ccaaaaatga gagtgtaata taaaccgtgt aagtaaccat caatcctagg cgggtggttg
     1381 cttcacggtt tttatttttc taaaataaga tcaagaggtg attacacgat ggctagaaag
     1441 aaaagaaatc ctgatgctga gaagttagct gaatccattt tgaatactta tcaacccgaa
     1501 tctgtagagg atatgcaaga tgttttaaaa gatgtgtttg gtcccttatt tgaaaaaatg
     1561 cttcaaggag aattgaataa ccatttaggg tatgacgccc attctaaaga gccaaagaaa
     1621 catgacaatc gacgaaacgg ttatggcaat aagacgctta aaacgagctt tggtaaagta
     1681 aacattgatg ttcccagaga ccgggaggct tcttttgaac ctgagttgat tcctaataga
     1741 aaacgagatg tctccgacat c
//
LOCUS       DAFLWZ010000185         1735 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000185 DAFLWZ010000000
VERSION     DAFLWZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.194"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(474..773)
                     /locus_tag="L1V38_002980"
     CDS             complement(474..773)
                     /locus_tag="L1V38_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317442.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(779..1009)
                     /locus_tag="L1V38_002981"
     CDS             complement(779..1009)
                     /locus_tag="L1V38_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317443.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1259..1459)
                     /locus_tag="L1V38_002982"
     CDS             complement(1259..1459)
                     /locus_tag="L1V38_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317444.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          604 a          270 c          260 g          601 t
ORIGIN      
        1 aagagtatta tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat
       61 gtatcctttt atggattaat gaaaggatgt ttcacatagt tatatttctg tatatttgaa
      121 aagttttact ttgattttta aatagaaaga catttgggtt atattgtgag ataataataa
      181 agaagagttt aaagcgttcc ccaaaaacca ctgccccata agtgtgttac gctttaaact
      241 cttttatatt tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag
      301 gcttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
      361 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
      421 tcataagtat ggtgataaaa tccgttccgg gctacctttt taggtagcct actttaatct
      481 ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgctt
      541 cgagcgtcta gcacatcagt cacgatatca aacaaaaaat atacgtcttt cttcattcta
      601 gttttcgcag cagggatttt aaagtagttc ttattagaat agtagagatt aattaataag
      661 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      721 aatctattcg aaggatcaaa tttaaaccat aattgcgtct cattaaaaag cataaccatt
      781 actccgatct atttttaaac ttagtctcta cctctaatat atatcgagtt tttattttgc
      841 cttcagagaa tactgtttct ttttttgcag ttacaggttg tttattttcg gaaaaagcta
      901 atatagctaa aattgaaaca tccatctgga atttgtcttt ttcgttgctt tgctcataaa
      961 aatctgcata ttcatcacta atattttttc taataaattc ttccatcata aagatcacct
     1021 cgaaaagagt atacgaacaa acgttctttt tgtaaaggtg gaatttatta tactaaataa
     1081 ataggtgaac aagtacttgt gccaaattat gtgccaaaaa aaatcgaatt taataaaaca
     1141 caaacaaaaa gaaatcctat tatgataaca tttcttataa taacaaacac aacagaagac
     1201 gtgtaatagt tagtcaggaa cgtacaaata acccctgtat cctttgcggt acagggggtt
     1261 attttgtata agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc
     1321 taagtatatt tactccttga taaagtaaaa tagatgcatg cgtatgtctt agtccatcaa
     1381 taaacagtcg aagagaaaat agggaaaaat tgattactaa agaaaaactt actaggtcga
     1441 cggtgtagtt gattttcata cttcaataga ttcgaattaa acgatttcga ttggcttata
     1501 ccagtcctat ccaacgaaag atatatcgtt cttaactcta gcggtataac ttgaagcttt
     1561 acgtaaagcc aatgggaatg aactggagat gactttttat tatttttagt aatagctgat
     1621 gggttaatac ttacaacttt ccttttcaaa gtaccatata aaaaaacggt ggggttgttt
     1681 agcgaaataa aggatctaag ccaatagctt agatccttta ttctatgctt tatat
//
LOCUS       DAFLWZ010000186         1732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000186 DAFLWZ010000000
VERSION     DAFLWZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.195"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(106..1053)
                     /locus_tag="L1V38_002983"
     CDS             complement(106..1053)
                     /locus_tag="L1V38_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1317445.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            1299..>1732
                     /locus_tag="L1V38_002984"
     CDS             1299..>1732
                     /locus_tag="L1V38_002984"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBN1317446.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
BASE COUNT          557 a          342 c          333 g          500 t
ORIGIN      
        1 agaagctact tctggaacac catttattcg gaaaaaagga ctgtgacaag acttttgtca
       61 cagtcctttt tcatttaaaa aaatgtttac ttcatttgac gtatattatt ggtgaggctt
      121 caattcattt ggcttcactt tttctgtttc tcttatgata taaacaggac gctgtttcgt
      181 ttctaagaag attttcccaa tatatttccc gatgattcca agacataaca attggattcc
      241 accaatgaac aggaagatcg agaccatgga aggccatcct gatgtaggat caccaaacaa
      301 caatgcccgc aaaataatga acaaaattgc aataccagaa ccgacacaag acaaagcgcc
      361 gataaatgaa gcaatcgtta acggtgcatc cgagaagttc acgataccat caatcgagta
      421 gttgaataat ttccagaagg accaagatgt ttcgccagcc acacgttcgc ggttttcata
      481 agaaatatat tctgttttaa atccgaccca gctaaataat ccttttgaaa atcggttgta
      541 ttctgttaat tctaggacgg catccaccat ttgacgagtc atcaagcgga aatcacgagc
      601 gccatcgacc atttctgtat cgctgatttt attgatcaac tggtagaatt ttttcgcaaa
      661 gaaactgcgt atcgcaggct cgccttcacg agtcgaacgc cgggtgccga cacaatcgat
      721 atcagaagta gtgatccggt tgatcatctc aggaagcagt tcgggcggat cttgcagatc
      781 aacatccatc acggtcacta aatctcctgt agaagcttgc aatccagcgt acagagccgc
      841 ttctttccca aaatttctgg aaaatgagac aaagcggaca taaggataag ctgaggctag
      901 cttcttgatt gctgctaacg taccgtcttt tgatccgtcg tcaataaaca aatattcgaa
      961 ctcatgggca cctttgaatt tttcaacctc atcaaaaaaa agaggaacag ttttttcttc
     1021 attaaaacat gggacaacaa ttgatacttt catcgtttct atcctttcaa tcgtatgttt
     1081 atatatggtt tacattcaaa atttaataaa ccttaaataa cacctttaaa atttgatttt
     1141 acgtaaaaga acaggtattc tttttgtaaa ctaacgtatt tagtttacca tgtttcctcg
     1201 gtttatcaaa cttttaagaa caatttttat tagttggcaa gtagttttgg atagagaaaa
     1261 aggaggaagt tccagtctat tgactaggag caaacaaaat gaaaatacac acacctatcg
     1321 gctttttatg gttagatgca gatgaatccg gattgactgc tgtatctttt cagccaattt
     1381 cagaaagcga atcagcgaat cagcgaattt taacgcgcac acaagaacag tttgaagaat
     1441 attttgcggg aaaaagaaaa gaatttgatg ttcctttatc tataaagaga ggtacgcctt
     1501 ttcagcaaaa tgtctggaaa gctttgtcga ccattcctta tggagaaatc cgaacgtata
     1561 aagaagtagc cgttgctgtt gatagtccga aagctgtgcg agcgattggg caggcaaatc
     1621 gaaccaatcc attgccaatc gttattcctt gtcatcgagt gatcgggcaa aatggaaaac
     1681 tgacaggata tatgggaaac gcaatagatg gggttgaaat caaacgccaa tt
//
LOCUS       DAFLWZ010000187         1704 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000187 DAFLWZ010000000
VERSION     DAFLWZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.196"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..182)
                     /locus_tag="L1V38_002985"
     CDS             complement(<1..182)
                     /locus_tag="L1V38_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1317447.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="L1V38_002986"
     CDS             517..951
                     /locus_tag="L1V38_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1317448.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="L1V38_002987"
     CDS             974..1294
                     /locus_tag="L1V38_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317449.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="L1V38_002988"
     CDS             1435..1626
                     /locus_tag="L1V38_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317450.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
BASE COUNT          642 a          257 c          361 g          444 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttct
//
LOCUS       DAFLWZ010000188         1703 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000188 DAFLWZ010000000
VERSION     DAFLWZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.197"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..551
                     /locus_tag="L1V38_002989"
     CDS             <1..551
                     /locus_tag="L1V38_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317451.1"
                     /translation="KKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            538..>1703
                     /locus_tag="L1V38_002990"
     CDS             538..>1703
                     /locus_tag="L1V38_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1317452.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAG"
BASE COUNT          561 a          220 c          275 g          647 t
ORIGIN      
        1 taaaaaaaat tcccaaaata gatgaaaaca gtaaattgat gaaaaacata caatcaatct
       61 ttgggataga agaagttttt gtcggagata aatgtatctt ttttgatcaa cctttattat
      121 ctgatggtta tggcatagat gaaacagata ttttcgctaa agtaaatagt atattttctg
      181 gaaaaaaaga aactttaatt aagcttcatc ctagagcaag gacaaatcgt tatggtgaaa
      241 aaaacatatt gaattccagt ttaccgtttg aagtcttgct acttgaaaat gacttctctt
      301 caacactttt gattagtcct atatctacaa tttctttttc accatctatg atgtttgaaa
      361 agacgatcaa ctctattatg ttggctaaat taattttaaa tgaatataca gcattatctg
      421 aagataaaaa agaaacattg acaaatattg ttcttttctg tgaacattat aaccgtctat
      481 cagaagaaaa aattttactc ccagaaaact gggcagaatt aagaaagttg gtagagtatg
      541 ggattattta acacactttc caagtcaaaa ttagttaagt ccagtttctg gtatactata
      601 gggaattttt ttattaaggg aatttcattc ataactattc ctatttttgt aaatattact
      661 actcaagcag aatatggttt gattaataat ttcacttcat ttgtatcaat tttttcgatt
      721 cttgttgggc taagcctaaa ttcggcaatt aataatgcaa gttttgacta taaagatgac
      781 ataaatgaat ttatgtcatc ggtactttct ctagctacac tttcgttaat tgtgttctta
      841 ttaataggga acatatattt tttgttttca aatgcttttt ttgatatgaa ccaacttgta
      901 tttaatttga tgttattaca aagttttgct agttttgtaa ttagttatat ccagtcttat
      961 tttacgatta actttaacca ttttaaatat ttgattttat cttttatatc tacttttttg
     1021 aatattgcaa tctctgtagc tttgatgcag acattatatt ttgatgataa atatgttggc
     1081 agagtagtcg gcggaacact gtcatttgtg ttgataggtt tagtaattta tttaagaata
     1141 atgataaagg gtgctcattt ttttgataaa aaacagtgga gatacgcttt aaaaatctct
     1201 ttgccgctaa tcccacattc cttagcaaat atagttttag cacaattcga tagaattatg
     1261 attaattctt atttaggtcc tgctgcgggg ggaatatatt cctacattag taacataggt
     1321 attattctaa gcgtaatatg gatgtctact aataacgcct gggttccatg gttctatggt
     1381 gagatgagta aaaataatga aaaaaaagtg aagaaagtta gtaactatta tttagtagtc
     1441 tttactttga ttacgatgat tgtaatggta gtttcgattg atttagcaaa atttatggct
     1501 ccgaaagact attattctgg gttatcttta gtggttccga taaccttagg ctatttcttt
     1561 cagtttttat atagtttacc agttaatgct gaattttatg agaaaaaaac atcgtttatt
     1621 gcgattggta cagtagcaag tgctatagtt aatatactat taaacatgat tttcatacct
     1681 aggttaggaa taattgctgc tgg
//
LOCUS       DAFLWZ010000189         1664 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000189 DAFLWZ010000000
VERSION     DAFLWZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.198"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            131..505
                     /locus_tag="L1V38_002991"
     CDS             131..505
                     /locus_tag="L1V38_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1317453.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="L1V38_002992"
     CDS             complement(619..1248)
                     /locus_tag="L1V38_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1317454.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="L1V38_002993"
     tRNA            complement(1382..1454)
                     /locus_tag="L1V38_002993"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAFLWZ010000190         1534 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000190 DAFLWZ010000000
VERSION     DAFLWZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.199"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            22..1488
                     /locus_tag="L1V38_002994"
     CDS             22..1488
                     /locus_tag="L1V38_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBN1317455.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          422 a          289 c          326 g          497 t
ORIGIN      
        1 taaagaattg gggtatagat tatggaaaaa cagcaagaca agggcttctt cgggcagccg
       61 aagggattgt caactttgtt cttcactgag atgtgggaac gatttagtta ttacggtatg
      121 cgtgcattac ttatctatta tatgtacgat acagttgcca acgggggact tggattacca
      181 cgagcaacag cattagctat catgtcgatc tacggatctt tgatctacat gtctagtatc
      241 gtcggcggat gggtatctga ccgagtgtta ggagcaaaac gcactgtatt cttcggtgga
      301 gttttcatta tgcttggcca catcgtcttg gctttaccat ttggtgtaag tacattgttt
      361 gtttcgatgg cattgattat tatcggaacc gcctttttga aaccaaatgt ttctggcatg
      421 gtcggacatc tttattcaaa gactgacttg cgaagagatg caggattttc gattttttac
      481 atgggtgtca acttaggggc attattagca ccactaatcg ttggtacaat cggtcaagaa
      541 tataactatc atttagggtt ctctttagct gctattggga tgttctttgg attattacaa
      601 tacatcatcc aaggacgcaa gacattagac ggagtgggta caacaccgcc gaatcctttg
      661 acaactgaag aacgtaaagg attcatccgt aacttgatca tcgcacttgt tgttatcgct
      721 gcagtattcg gcggggcaca actaactggt catctgacaa ttgacttttt tgtcaataca
      781 atcagtgtat tggggattat cttaccgttg tattacttta tcaaaatgct gacttcaaaa
      841 gatgtaactg ctgaagaaaa accaagagta tgggcttata tcccattatt ccttgcagca
      901 atcattttct ggtcattaca agaacaaggt tcatctatct tagctttatt tgctagtgaa
      961 cgtacacaat ctacgctatt tggtgtaacg atccaagcaa gctggtatca atcattgaat
     1021 ccaattttca tctttattct gacaccagta ttcgtaacga tgtggacgaa acttggtgaa
     1081 cgtcaaccat ctacagtagt gaaattctct cttggacttt tatttgcagg attatcgtac
     1141 ttgctattga tgttgccggg tatgctttat ggtacaagtg gaaaagtaag tccattgtgg
     1201 ttgttgggaa gtttcttcat cgtggttatt gctgaattgt gtctttcacc agttggtttg
     1261 tctgtgacaa caaaattagc accacgagca tttgaatcac aaacaatcgc tatttggttc
     1321 ttagctgatg cttcttcaca agcaatcaat gcacaaattg cacgcttcta cacaccggga
     1381 acagaatctg cttacttcgg tattatcggt gcagtagcaa tcgtcggtgg tatcttgcta
     1441 tttactgtga aagaaccaat caaaaaacta atgggctcta ttcattaatc aatgaacata
     1501 aaaacaggaa ttgcttattt gcagcagttc ctgt
//
LOCUS       DAFLWZ010000191         1507 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000191 DAFLWZ010000000
VERSION     DAFLWZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.200"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..340)
                     /locus_tag="L1V38_002995"
     CDS             complement(<1..340)
                     /locus_tag="L1V38_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317456.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNP"
     gene            complement(342..1400)
                     /locus_tag="L1V38_002996"
     CDS             complement(342..1400)
                     /locus_tag="L1V38_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBN1317457.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
BASE COUNT          587 a          242 c          183 g          495 t
ORIGIN      
        1 ctggattttt tttgtaaaca ttggagaaaa gtatttttgt gaaataattt tccccctgta
       61 taaaaatttc atcataaacg gataaatcat ccgagaaaaa ttgattatgg ttagttaaca
      121 agttaatttt acgtttaaag gaagaaccga ttttccggtg attcacaaaa acaacatcat
      181 taaatagccc taattctttt atacgctcac tatatcttct agcgttttca aattcagaat
      241 aaataaataa atctcctttt gattctcggt aaaaattttg ataaacattt aatatattaa
      301 tcaaatgtaa aggagtccaa gcaatgaaag ctgtcttcat attaattctc cttttttaaa
      361 tacaagtaag aaatgcttcc caaataatac cagaaaacaa ttgaaatgac atcgcgctta
      421 ttgaaaagta catgagcctc caccatttca tctataaaaa tagatagtat aaaaattaaa
      481 acaataccaa gaaacgcata attcacttta cttctaaaaa atgttttgag taaactaaag
      541 atatttaaca catagaaagc atagatacat ataaaagcaa ttataccact tgatacaagt
      601 acttgaagaa atccattatg catgtttcca tgtgctcttt ttagttcatt cacatctgta
      661 gtatcaagat ctactttttt caaaaatttt gcatcgctat tcccatagaa atcggtctct
      721 ccataaccaa ataacaaagt tggtcttata actttaagcg cagctttcca aatcgtaaaa
      781 cgaccagctg aaatttcgga gttatcacta gaatgctgta atattacttc tttttctgga
      841 agtggagttt tatctgattc atttgactct ataacttcta cttttctatc aatcgataca
      901 ggaattgttg ctaaaaaatc cttagcataa ttagtaccaa aagaaaaata taccaataga
      961 actaataata tgcttaccat ccatttgatt tttacaggta gtacttctct aatgctcttt
     1021 ctaaattttg aattggcaaa caacaaaaga aataatacta aaaaagaaca aattactacc
     1081 tgggcacctc tagacgaaga aagtgtaata taaaatattt gtacgataaa attcatcata
     1141 taaaaaacac gaatcgtttt tgttattttt gaaattaata cactaattaa acttaaaata
     1201 atagaagtat atccaaacat agctccaaca tttggacttg tatagacacc aaataaccga
     1261 tgttcaataa aaccttgtct tgcaagtaat cctggcgttc ctgttgggac atgataagaa
     1321 atcaaaaaaa taaattgata gatagatatt agcgcagcta aaaaaattat gataatgaaa
     1381 acattattaa aatacaccat ttttttcttt ttttcctctt cactttgtga aaagtctgca
     1441 ggaaaaatta ctatcaaagt aatcagcaaa tatccaaaat tataaataga tggaattaaa
     1501 aaatttt
//
LOCUS       DAFLWZ010000192         1498 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000192 DAFLWZ010000000
VERSION     DAFLWZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.201"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(606..962)
                     /locus_tag="L1V38_002997"
     CDS             complement(606..962)
                     /locus_tag="L1V38_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1317458.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="L1V38_002998"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="L1V38_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1317459.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          460 a          274 c          213 g          551 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta aatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttga
//
LOCUS       DAFLWZ010000193         1480 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000193 DAFLWZ010000000
VERSION     DAFLWZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.202"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            64..972
                     /locus_tag="L1V38_002999"
     CDS             64..972
                     /locus_tag="L1V38_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1317460.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="L1V38_003000"
     CDS             972..>1480
                     /locus_tag="L1V38_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317461.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DAFLWZ010000194         1364 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000194 DAFLWZ010000000
VERSION     DAFLWZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.203"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            82..>1364
                     /locus_tag="L1V38_003001"
     CDS             82..>1364
                     /locus_tag="L1V38_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBN1317462.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAFLWZ010000195         1355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000195 DAFLWZ010000000
VERSION     DAFLWZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.204"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1355
                     /locus_tag="L1V38_003002"
     rRNA            <1..1355
                     /locus_tag="L1V38_003002"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFLWZ010000196         1350 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000196 DAFLWZ010000000
VERSION     DAFLWZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.205"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..969
                     /locus_tag="L1V38_003003"
     CDS             <1..969
                     /locus_tag="L1V38_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1317463.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1159..1232
                     /locus_tag="L1V38_003004"
     tRNA            1159..1232
                     /locus_tag="L1V38_003004"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ile,seq:cat)
BASE COUNT          439 a          241 c          272 g          398 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccata aatagtcaca
     1081 ctccaagcta tgcgataaca ggtttgttgc cacacattct actggttgat tgtttatggc
     1141 tttatgtggc aacaaccagt acccttagct cagttggtca gagcagacgg ctcataaccg
     1201 tccggtcgta ggttcgagtc ctacagggta cattaacgta gccatttgaa tcgttctgtg
     1261 ttagaatttt tttgaagagt attatacaag ctaaagcttt tcttcattgc cactcaaatg
     1321 agtggctttt ttatgtatcc ttttatggat
//
LOCUS       DAFLWZ010000197         1350 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000197 DAFLWZ010000000
VERSION     DAFLWZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.206"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            549..1082
                     /locus_tag="L1V38_003005"
     CDS             549..1082
                     /locus_tag="L1V38_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBN1317464.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          430 a          249 c          254 g          417 t
ORIGIN      
        1 cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg
       61 tgaaaaagct gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt
      121 tttcgtttgg ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag
      181 ttgtgaaatc agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat
      241 attttgctat tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga
      301 agttgtgaaa aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca
      361 caactttgca taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc
      421 acaaggaatg agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt
      481 tttttgttaa atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt
      541 ttacagaaat gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg
      601 cttgttctct tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat
      661 tgatacagcc tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag
      721 aagacgtacg caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc
      781 aaaaaaatcg tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat
      841 gcttagatta ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta
      901 gccgtcgcct gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga
      961 acatccaatt agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc
     1021 tgctttatca agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt
     1081 aaaagaatac ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac
     1141 aaggagcaat ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag
     1201 gagctggcag gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt
     1261 aataagaaca gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc
     1321 gcagatgcaa gcttttggac accgtttacc
//
LOCUS       DAFLWZ010000198         1336 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000198 DAFLWZ010000000
VERSION     DAFLWZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.207"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(112..1260)
                     /locus_tag="L1V38_003006"
     CDS             complement(112..1260)
                     /locus_tag="L1V38_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317465.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          385 a          236 c          210 g          505 t
ORIGIN      
        1 tgggagcttc ttgggaatag agcatacttg atagcgtatt tctttactaa cagcggtgtc
       61 tcttatttac caagctatcc ccgtagttcc tacggttctt gatgattgga tctaagccaa
      121 tcccatagaa tgtagtctta gaccttcggt cagaatattg atactagcat tgatatcacg
      181 atcatgatga gtatgacaaa caggacaagt ccattctcga atttcaagag atttcttgcc
      241 atctttatgt ccgcactctg aacaaatctg actagacgga aaccatttat ctactttgat
      301 gatttttcgt ccataccagt cagccttgta ttgtaattta gtcacaaact ttgaccaaga
      361 aacatcagaa atacttttag ctaatttatg atttcgcaac ataccttttg tgtttaagtc
      421 ttcaatacag ataatatcgt gatttttgat catttctgta ctcaacttat tcagaaaatc
      481 agtacgttga ttcattactt tttcatgcaa tctagctact ttgcgttttt gtttttgata
      541 atttttagct tcaaatagat tggtaccttt atttttagcc aataaagcac gcctagacaa
      601 tttgcgttgt tcacgcttta gtttcttttc cattttggac gtgaatttat tattatcaat
      661 tttttgtcca tcagaaagaa tcgcaaagtc cataatacct aagtcaatac caattgtgga
      721 attagtttta ggtaattcga taatttcttc tttacacaac aaagaaatat agtatttacc
      781 gctagaatga cgtgatattg tagcagattt gataatccct tttggttgtc tatgaagctt
      841 aattcttact aatgacttca atttaggaac tttgatgaat ttactatcaa tcaaagcaac
      901 tgtaccattt tgattattcg ttgtataact ctgaacagga tttttcttac ttttgaaacg
      961 tggaaatcca acggatttat cccgaaaaaa attcttgtat gctttatcta aattaagttg
     1021 ggcattggct aaagcaaggc tatcaatttc tttcaaaaac ggaaattctt tcttgtattt
     1081 agctggtgtc ggaaaagtca tttttttaga agaatcattt ttaacttctt catacgcctt
     1141 ttttcggtca tcaagcatta gattgtagac cttacggaca caaccaaaag atttggcaaa
     1201 gaagatttct tgttcctctg ttggatagat tctgaatttg tatgctttta gttgttccat
     1261 aaagttcacc tactttctat ttatgattgt ttccttgatt ttggatatac ttcttaatca
     1321 catcaattgg tgcgcc
//
LOCUS       DAFLWZ010000199         1331 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000199 DAFLWZ010000000
VERSION     DAFLWZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.208"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            122..>1331
                     /locus_tag="L1V38_003007"
     CDS             122..>1331
                     /locus_tag="L1V38_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1317466.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          415 a          261 c          255 g          400 t
ORIGIN      
        1 gctctatact ttttgatgtt ggtgaacttc accaacatct tttttgtata aaaaaatata
       61 gaaaagacac cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa
      121 gatgtctcat actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt
      181 cgaggaaaat tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg
      241 aactcttctg tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat
      301 cattcgttgg gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac
      361 ttatctggag ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc
      421 ggatacctct gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat
      481 tgctcgctta aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac
      541 ttcttcggtc tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac
      601 tttgccaaag gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat
      661 gagttttatc atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg
      721 cttgccttat ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca
      781 attgattgtt attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa
      841 tgctcagttg atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa
      901 tcatcgagtg aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt
      961 agggaaaaaa ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta
     1021 tgaaaaacgg gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga
     1081 tcgactgtta gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct
     1141 ttatgcggta aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag
     1201 cggtctgcca gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat
     1261 ccaaaatgcg cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat
     1321 caaagtatta a
//
LOCUS       DAFLWZ010000200         1279 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000200 DAFLWZ010000000
VERSION     DAFLWZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.209"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            282..521
                     /locus_tag="L1V38_003008"
     CDS             282..521
                     /locus_tag="L1V38_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317467.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="L1V38_003009"
     CDS             complement(883..1143)
                     /locus_tag="L1V38_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317468.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          426 a          233 c          174 g          446 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccg
//
LOCUS       DAFLWZ010000201         1248 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000201 DAFLWZ010000000
VERSION     DAFLWZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.210"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            200..742
                     /locus_tag="L1V38_003010"
     CDS             200..742
                     /locus_tag="L1V38_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317469.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1248
                     /locus_tag="L1V38_003011"
     CDS             898..>1248
                     /locus_tag="L1V38_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBN1317470.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPD"
BASE COUNT          515 a          141 c          238 g          354 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagat
//
LOCUS       DAFLWZ010000202         1219 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000202 DAFLWZ010000000
VERSION     DAFLWZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.211"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..460
                     /locus_tag="L1V38_003012"
     CDS             <1..460
                     /locus_tag="L1V38_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBN1317471.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="L1V38_003013"
     CDS             469..696
                     /locus_tag="L1V38_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317472.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DAFLWZ010000203         1212 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000203 DAFLWZ010000000
VERSION     DAFLWZ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.212"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            146..1186
                     /locus_tag="L1V38_003014"
     CDS             146..1186
                     /locus_tag="L1V38_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1317473.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          487 a          176 c          201 g          348 t
ORIGIN      
        1 cataattcat tttatttctg attttaggta gtatttaatt aaaaaacagt tttaatgcgt
       61 ttgcattttt tatttatctt tgctattttc gaaaagagta ggtaatttta cataaataaa
      121 acaacgtgaa agtagaggat ctacaatgac tgattttaaa ttttttaagg cggatagagt
      181 ttacaacgaa ttattttatc aatttccaaa agtctttatt gtttctgacg aatacaaaaa
      241 aatgaaagat tcaactaaga ttgcctatat gcttttaaaa gcaagattag agatcgcaat
      301 cagcaaacgg caaatcgatg aagaaggtaa tgtttatttt acttatacga caaatgaact
      361 atgtagagta ttaaactgcc aaaaacaaaa agcgatagca atcaaaaaag agttggaatc
      421 ctttggttta ttattacaaa agcagatggg atttaacaaa cagttaggga aaaataatcc
      481 taatagacta tatctagcag aattaaaagt ctcagaaaat gatatctact tactcgaaaa
      541 atttgataga gagaataggg aaaacgttga taaatcagag ggtatgaaaa tcatacccac
      601 cctcgacgaa aaatcagacg ctgaatccct tggggctcaa gagggtatga aaatcatacc
      661 gtgccaaaac gttgataaat cagagggtat gaaaatcata ccagaactta ataataatat
      721 attagacact aatagacaca atatagacac tgaaaaagac cgcctacaag atcaattgtt
      781 gttagacaat tttgagacaa ttatgacaaa cgacagcatt gctacgtttg tccctgaacg
      841 agtattaaat ttgataaaaa cattttcttc aagttacagt gaagctcaaa aaaccgtcca
      901 gactattcat aatgcaaaga aaaaagctga aatagaaagt gatatttcga tagtttttga
      961 agaactcgat agttattatg tcaatgcaga acaagaatta tacacgacac tgttaaaagc
     1021 ctatcaaaaa ttaaaaaccg aaaaagtcga aaatatccag aacctgattt ttgtctatgt
     1081 aaaaaattgg tttatcgaaa aaccaatagc tgctaaagta tcaagtgaaa aacgtttgaa
     1141 ttatgcaagc tccccaagca ctattacgaa agactggtta gagtgaaact ttactgacaa
     1201 agtgattgtt gc
//
LOCUS       DAFLWZ010000204         1195 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000204 DAFLWZ010000000
VERSION     DAFLWZ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.213"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1076
                     /locus_tag="L1V38_003015"
     CDS             <1..1076
                     /locus_tag="L1V38_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1317474.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAFLWZ010000205         1186 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000205 DAFLWZ010000000
VERSION     DAFLWZ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.214"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..739
                     /locus_tag="L1V38_003016"
     CDS             <1..739
                     /locus_tag="L1V38_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1317475.1"
                     /translation="KINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKA
                     IKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQE
                     LEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKEL
                     SSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVL
                     ENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            811..>1186
                     /locus_tag="L1V38_003017"
     CDS             811..>1186
                     /locus_tag="L1V38_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1317476.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKN"
BASE COUNT          520 a          136 c          194 g          336 t
ORIGIN      
        1 taaaattaat aatttattca agaatgacaa tgctgaatta aggaagggtc ttttagagtt
       61 taaacttcaa gaactagaac ttcattactc ttatttagtg aaaattaccg aagaaaaaga
      121 acaacaaaaa gcaataaaag aacagatgat agaagaggaa aaagttcgta gagaaattga
      181 tcgtgaaaag aaacgtattg ataaagaaca acgtcaattc aattctgaaa tttccaaatt
      241 aatcgcatat atgcaaaaag ctaatgcaga tgtggaaaaa gaattatatg caaataaaat
      301 tcaagaactg gaagaaaaat taaaagaatt agaagttata cgtgaaaatg tattacaaag
      361 agaattaaat actagagccg gttatgtgta tgtaattagt aatattgggt cttttggtga
      421 agacatatat aaaattggta tgactagaag attagaacct atggatagaa taaaagaatt
      481 gagtagtgca tcggttccat ttgaatttga cgttcatgcg atgatttttt cagaggacgc
      541 tccgtctttg gaaactaaat tgcataatca ttttagaaaa caagaagtta ataaaattaa
      601 tcaaagaaaa gaatttttca aagtttcact agacgaaata gagaaagttg ttttagaaaa
      661 ttataatgga acagtaacat ttacaaaatt agctaaagct gaacaatata gacgatcttt
      721 agaattgtca aaagattaaa tatataaaaa gccttcgggc tttttctttt aacaattaat
      781 aggaacgtat attcgaaagg aatagaaata atgtggttag aaaaaataaa tgacaaaaaa
      841 tttaagtaca ccgaacgtta tacggatccc ttaactgaaa aaaagagaaa agtgtccgtt
      901 actttatcta gcaattcacg ccaagcttgg aatcaagcta acttactttt gaatgaaaaa
      961 atcgcagaaa aaataaaacg aaatgaagaa ttaccactaa cttttggaga attaaaaact
     1021 aaatgggatg aaaaatacaa gccaactgta aaagaaagtt cctatcgaac aactcaggtt
     1081 tatctatcat taatttcaaa atatataaaa gatgatgtac ttgtaaaaaa cgttaatagt
     1141 aatcttatac aagatatgct agattactac tattttgaaa aaaatt
//
LOCUS       DAFLWZ010000206         1154 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000206 DAFLWZ010000000
VERSION     DAFLWZ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.215"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            43..>1154
                     /locus_tag="L1V38_003018"
     CDS             43..>1154
                     /locus_tag="L1V38_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317477.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRR"
BASE COUNT          378 a          153 c          156 g          467 t
ORIGIN      
        1 gtttaaaaaa aataaatgat actatatgta atataaaaaa acatgaggtg gtatatgaat
       61 ttgaaaaaaa ttttttctgt aaaaatattt atagtttatg catttgttag tttattatat
      121 ttatttccag catttaaaaa catggaaata tttggctttt atgatacggc atttcacatt
      181 aatcgtgcgt taagtttaga atctattttt agctccccta ttaattttga aacgtttaga
      241 tcatatggca tgcaagtaaa taatttttac ccatggttaa ctctatatcc tttattttta
      301 ttgatcaagt ttactaattt agcaataggc tataaccttt ttctttatat tgttacgctc
      361 attactctat ttatatgtca ttatgtaatg tatgaaatta ccaaaaaaca tgttactagc
      421 tcctttttcg ctattatata tacaacatct tcttttagga gtgtagaaat atttcttcga
      481 ggggcaatgg gggaattact cgcaatgtca atacttcctc ttattttact cgggtttata
      541 aagctttacg actcaaaaaa agaatcttgg gttatgttgg cgattagcat gactttatta
      601 atttacactc atgttctttc tgtagctatg actatggtaa tgattataat tgctttaatt
      661 attcaatttt atcggaaaaa gaaaatagaa atcttcttaa ttattaaatt aataaaagct
      721 gctatagtta ctttacttct ttcactagcg tttataggtc ctatgattga gcagacattg
      781 tatcaagatc tgaatagacc ttatgtggat atattacaaa aaagagcaat ttatctgggt
      841 aaagagtttt tgattggaag tatagattca gaattactat catttggtat tggcttaact
      901 ttgcttattt gtttaattat actaacattt aactttaaaa aattaggaat cttatctaaa
      961 atcacttata taatgggtat aatatctatt ctactttgta caaaaatatt tccatggttt
     1021 gccttacaaa atactccttt aaatattatt caagctcctt ggcgttttat gatattttca
     1081 acattgttca tatctttttc agtatctcta tttatttctc cacagttgga aaaattttct
     1141 tatacaagga gaag
//
LOCUS       DAFLWZ010000207         1125 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000207 DAFLWZ010000000
VERSION     DAFLWZ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.216"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..855)
                     /locus_tag="L1V38_003019"
     CDS             complement(<1..855)
                     /locus_tag="L1V38_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317478.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGT"
BASE COUNT          358 a          209 c          117 g          441 t
ORIGIN      
        1 tgttcctata aaatcaagtc ctctacattt taaaggttca cttaaactat taatatagtt
       61 aataatgttg tctatccttt tctctttatc ttcaccttca atctggggag catatagtcc
      121 aatttcctcc caataatatg aatctctttc aattcccatg atggtagctt tggctaattt
      181 caaatcaaat aacgatttta gaattcttag tgtctcaata aagtcttctc tcttcaactc
      241 tttaatccat tgtgaatttt ctggattatc taaaatttca agttcatctt cattataagt
      301 atatttcaaa tttgacttgc ttaactcata gataaatgaa gtttcttgac tcataattct
      361 tttaagtact tgactataag tttcgtttga ctttgcccat ttcgctaatt ctaccactgt
      421 attcactaat aaatcgaaat aatgatgttc tcgttcaata gtctcagcat tttgaaaatg
      481 aaaatcacct ttataaactc cattcttttc cactgtttta ttaatatttt ttaaaaacca
      541 gaatgagttt gcaaatttag tcgtactttt tcgattaact aagttaataa ctcttccatg
      601 taataataag acaaaaatac ataaattttt agcttcctta ttattagata ctaattgatc
      661 aatcataggg agccattttt tgattttcac taattgattg ctcataaatc tttcactgga
      721 cttttgttca atcttaaatt gcaaaacttc taactcataa ttcccatctt ctgatttatt
      781 tttgggaaca actatcaaac ttttataaag tttatccaca tcaaaattta tcttttttgc
      841 ataatttgta gccattaata catctcctta ttcataataa atttcatatg acgctcctct
      901 caaaatttac cggtagacta gaaaaaagaa taaaagatac gtcaattcac actttattct
      961 taaaaaaaaa ctggtctctc taccggtaat atcgattgag tccgccttta tcgactttat
     1021 ccttttttta tattaaattt tttcaccggt agacagggag agaaagaata aactaaaaag
     1081 cccttaattc ttaatgtttt cacctcctta ccgttcctac cgcta
//
LOCUS       DAFLWZ010000208         1112 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000208 DAFLWZ010000000
VERSION     DAFLWZ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.218"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(267..971)
                     /locus_tag="L1V38_003020"
     CDS             complement(267..971)
                     /locus_tag="L1V38_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317479.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT          321 a          194 c          199 g          398 t
ORIGIN      
        1 cttttttctc tatcagaaaa tatgtttatt attagaattt tttatagtta aggttaggca
       61 tcttaagaaa tcaggcaact ccaagatatc ttcaggtaga agagaagtcg cctaacattg
      121 taggatcata ggtgatttgt tggacaggtc aagctgatat ttgagcctga tgttagaagg
      181 aatttctttt tacttgctgt agaaattatt atatgactaa aaaggctggg attttaaatc
      241 ccagcctttt atgacaaata gaatttttat cgatcagtaa tcgctgtcgc tgcaaattgt
      301 tcgatcaaag gaatcaaagt caatttgact ttgtatttcc gttcgagtgc tttttcgata
      361 acgaactcat tttcagtagt catagaaata gttgctaatt tacgaggttc atcagcattt
      421 ttttcattaa taactacttc atgttcattt tgttctgtgt aaaatttagg atactcagca
      481 acggcttttg aaaaatcagc aaaacttaaa gcggcattcg tatcagttga gcgtgtattt
      541 tcagttgtgt ccgcttttgg tttttccgtt ttttcttctg gcacactgac tgtttcttct
      601 gtaactggtg tcgcaacagc ttgcgcagtt ggttcatcgt ttttcaatcg ttgatcattc
      661 cagtaagaca cgatttcaat aagaagattg tcacggaatc gttcgaaaat cccgttttct
      721 cctgaacgaa ttctctttaa tacagtattg aagttgtcat cgattggcac gttgatccgt
      781 gtatcttcat ttgttttccc agctaatccg atcgttaaga tttgacggtt tttgggatca
      841 agcatgactt gtaacggcaa accataacgt cgcaagctct cttcttctag agaacggaat
      901 aattgtcctc ttacaccatc caatgaagga cggaattgat ttaataattt ttgtttctgt
      961 tttttcttca tatgttctct ccttcgctca taccctttcg attataagaa aaaaacagcc
     1021 aaatgaaaag gagtaatgca aaaaaacttg cgtatacgca aattacaaca gaaaaatttg
     1081 cgtattttcc cgttttttga aagaaaaata aa
//
LOCUS       DAFLWZ010000209         1085 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000209 DAFLWZ010000000
VERSION     DAFLWZ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.219"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(60..278)
                     /locus_tag="L1V38_003021"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="L1V38_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="L1V38_003022"
     CDS             complement(544..738)
                     /locus_tag="L1V38_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317480.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="L1V38_003023"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="L1V38_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          377 a          186 c          157 g          365 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgat
//
LOCUS       DAFLWZ010000210         1060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000210 DAFLWZ010000000
VERSION     DAFLWZ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.220"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(111..184)
                     /locus_tag="L1V38_003024"
     tRNA            complement(111..184)
                     /locus_tag="L1V38_003024"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(148..150),aa:Ile,seq:cat)
     gene            complement(739..1053)
                     /locus_tag="L1V38_003025"
     CDS             complement(739..1053)
                     /locus_tag="L1V38_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317481.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          397 a          165 c          166 g          332 t
ORIGIN      
        1 aaaggataca taaaaaagcc actcatttga gtggcaatga agaaaagctt tagcttgtat
       61 aatactcttc aaaaaattct aacacagaac gattcaattg gctacattaa tgtaccctgt
      121 aggactcgaa cctacgaccg gacggttatg agccgtctgc tctgaccaac tgagctaagg
      181 gtagtggttg ttgccacata aagccataaa caatcaacca gtagaatgcg tggcaacaaa
      241 cctgttatcg catatcttgg agtgtgacta tttatgagtg atagtgaaga tatgcgtctc
      301 catatatgta tggttgagac agataaacat gtatgaaaaa cgttgttaaa tcaacgtttt
      361 tttattttgg tcaaggagag aaaagtagag aaatacaaaa ttttttgcat tgattttgca
      421 ttcaaaaaaa cattcaaaca tttagaaatc cccaatacgt attcaggaaa atctatttta
      481 aggtttacaa aaagaacttt tgttcgtaca ctctttttga ggtgaacttt tatgctgatg
      541 gaaggaaaaa cacaattatg gtttaagcat gttccttcaa ataagttttt taattataaa
      601 ctctagagaa attaattcat cctaacataa aataattgtt cactcaaaag tttttctaga
      661 acaattaaaa cagcaggctt cacattcgct atacatttgt aagaagtaat aattcctgta
      721 ctaaaaggca taattgcttt aattattttt tgacttctct tcaaacacaa gaagtagttg
      781 tgtaataatt gcagaaataa ggattccaat aatagatata aaatttgaca tggaaacgtc
      841 tataacatta aaagaataaa gtgttgaaga aagtaaactg attgaaataa cccctccgta
      901 aaaaatagtc tgtgaatata cccacttttt ttcagaagac gtacttcgtt tggttctaaa
      961 acctatccct gcatttctac tcttatcaaa aaaccaaata tttagaagta ataatattgc
     1021 tattattaag ataaaattac tgtaaaaatc caaaagctat
//
LOCUS       DAFLWZ010000211         1060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000211 DAFLWZ010000000
VERSION     DAFLWZ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.221"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            93..1052
                     /locus_tag="L1V38_003026"
     CDS             93..1052
                     /locus_tag="L1V38_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317482.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
BASE COUNT          385 a          190 c          198 g          287 t
ORIGIN      
        1 ccgattgtaa aattaagcta gacaactaaa aaaagtcatt tgtgctacac tcaaaatagt
       61 tccgacgaaa gaattataag gagtgagtac aaatgaccta taaccatctt acaccaactg
      121 aactcgtaat gatagaagct tatttcaatc aatcacaacc tgtttcaaaa gtagccaatc
      181 tgttacaacg ttctcgacaa actatttata aggtctatcg ttttcttaaa tctggtggaa
      241 gcgcaatgag ctactataaa caatataaga aaaacaaacg taactgcgga agacatccga
      301 ttgttttacc tgatgagcaa caggaataca ttcaaaaaaa ggttgttcaa gggtgggctc
      361 ctgatgtcct tattggtcga gcagagtttc ctattgcttg ttcggtacgc acactgtatc
      421 gaatgtttaa agataaaacc tttgacactc acgatttacc aatgaaggga aaaagaaaac
      481 caaacggtca taaagaaaaa agaggaaaac aagggtttcg ccggtcaatc cgagacagaa
      541 agacagacta tacccagttt gatcatgaat ttggtcacct ggaaggtgac actatcgtgg
      601 gtggaaaaca taaaagcgcg gtcatcacat tagttgaacg gctatctaaa gtcatcatta
      661 ccttgaaacc cgaaggcaga caggctaaag acattgaaaa taggctgaat caatggtttc
      721 gttgtgtccc aaaaaactta tttaaatcca tcacatttga ttgtggaaaa gaattctcaa
      781 attggaaaaa gattagtaat accaacgata tttcaattta ttttgcggat ccaggaacac
      841 cttctcaacg aggattgaat gaacattcaa atggcttatt acgtaaagat ggtttgtata
      901 aagctatgga ttttaatggt gtatctgaaa cctttatcca atcggtggca tcgaaacgaa
      961 atcatattcc tagaaaatca ttacactatc ggacaccaat ggaagtattt ttgagttacg
     1021 tcacaaaaga tgatttgtct aacttaattt gacaaacgaa
//
LOCUS       DAFLWZ010000212         1059 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000212 DAFLWZ010000000
VERSION     DAFLWZ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.222"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(37..993)
                     /locus_tag="L1V38_003027"
     CDS             complement(37..993)
                     /locus_tag="L1V38_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317483.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DAFLWZ010000213         1035 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000213 DAFLWZ010000000
VERSION     DAFLWZ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.223"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..>1035)
                     /locus_tag="L1V38_003028"
     rRNA            complement(<1..>1035)
                     /locus_tag="L1V38_003028"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAFLWZ010000214         1004 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000214 DAFLWZ010000000
VERSION     DAFLWZ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.224"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            37..432
                     /locus_tag="L1V38_003029"
     CDS             37..432
                     /locus_tag="L1V38_003029"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBN1317484.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            634..1004
                     /locus_tag="L1V38_003030"
                     /pseudo
     CDS             634..1004
                     /locus_tag="L1V38_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          403 a          129 c          195 g          277 t
ORIGIN      
        1 gataatttta catttgaatt acaatagggg gctataatga aagttacaat gttaaaagga
       61 aaaatacata gagctacagt tgaacaagct gagttagatt atgtaggaag tattactgtt
      121 gatatgaatt tattagaagc agcaggaata tatgaatatg aaaaagtaca aatagttgat
      181 gttaataatg gaaatagatt tgaaacttat acaatagctg gagagagagg aacagggatg
      241 atttgcttga atggagctgc agctagatgt gtatcaactg gagataaaat aattttaatg
      301 gcatattgtg aattaaatga aaatgaggtt aaggatcata gacctaaggt tgtttttgtc
      361 gatgataata ataaagttga aagagtaaca tcatatgaaa aacatggaag gttatcagat
      421 ataattcttt aggttttgta atgttattta tatatagcta gactattatt gaaatattta
      481 ttgattacta attggataga tgtcaataaa gtagacacaa aaagagaaga tacagactgt
      541 agacaaagtc cattttatgt gaatcggcta cactagacta gacagaaaaa ataaggtgtg
      601 tagaataata aaaaacacac tggaggattt ttcatgtcaa gacgtcaacg aagaacctat
      661 tcaaaagaat tcaaacaaca aatcgtcaat ctctatctcg ctggtaagcc tcgcgcagaa
      721 attattcgag agtatgagct tacgccttct tctttcgata aatggatgaa gcaagcacaa
      781 tcaacgggct cattcaaaaa aagagacaac ttaacaccag aacaagcaga attgatcgca
      841 ctaagaaaga aaaataagca actcgaaatg gagaatgata ttttaaagca agcggcgctg
      901 atattcggac gaaaagacaa gtaattgatg ccaacaagca taaatattcc atatcagcga
      961 tgtgcaaaat tctaaatatt tctcgtcaga cctactatta tcaa
//
LOCUS       DAFLWZ010000215         1000 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000215 DAFLWZ010000000
VERSION     DAFLWZ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.225"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            369..1000
                     /locus_tag="L1V38_003031"
                     /pseudo
     CDS             369..1000
                     /locus_tag="L1V38_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAFLWZ010000216          986 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000216 DAFLWZ010000000
VERSION     DAFLWZ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.226"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>986
                     /locus_tag="L1V38_003032"
     CDS             <1..>986
                     /locus_tag="L1V38_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1317485.1"
                     /translation="LEPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITD
                     SEYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQL
                     DDTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTG
                     KKNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVG
                     SIAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFY
                     ENFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 ttagaaccag gcgattttat catgagtggc gctggaacaa ttgggagaat ttcaagagta
       61 ccaaagcaaa taaaaccggg tgtattcaat caggctttga ttagacttag aataaataaa
      121 gaaatcacag attcagaata ttttattcaa tttattcgtg cagattttat gcaaagaaaa
      181 ctcacaggag ctaatccagg ttcagcaatt acaaatctcg taccaatgtc agaagtgaaa
      241 aaatggatag tacaatttcc aatattagaa gaacaaaaga aaattgggaa cttcttcaaa
      301 caactggacg acactatcgc tcttcaacaa cgtaagctag atttattaaa ggaaacgaaa
      361 aaaggattct tacaaaaaat gttccctaaa aacggagcaa aagtgccaga aattcggttt
      421 cctggattta cggaagattg ggaacagcgt aagttcaaag agtttagtaa gaagactgga
      481 aaaaagaaca cgaaagattt agacttccct gcctattcgg taagtaataa agcaggttta
      541 atttctcaaa cagaacagtt tgatggtagt aggttggatg atttagaaaa aacaaattat
      601 aaattcgttg aaccaaatga attcgcctat aatccagcaa gagtaaacgt aggatcaatt
      661 gcatttaaca atcttggtat gacggtcatt gttagctctc tttatgtagt tgtgaaaatg
      721 agcgaggact tagataatga gttcatactt cagtttatca agtcaccaac atttatcaaa
      781 gaggtcaagc gcaacactga aggaagcgta cgagaatact tattctatga gaatttcgct
      841 aatatcaagt ttccttttac taggaataaa gaggaacaac aaaaaatcgg cgctttcttc
      901 aaacaactcg acgacacgat cgctcttcat caacgtaagt tagatttgct gaaggaaacg
      961 aaaaaaggct tcttacaaaa gatgtt
//
LOCUS       DAFLWZ010000217          943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000217 DAFLWZ010000000
VERSION     DAFLWZ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.227"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>943
                     /locus_tag="L1V38_003033"
     rRNA            <1..>943
                     /locus_tag="L1V38_003033"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAFLWZ010000218          929 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000218 DAFLWZ010000000
VERSION     DAFLWZ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.228"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            787..>929
                     /locus_tag="L1V38_003034"
     CDS             787..>929
                     /locus_tag="L1V38_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1317486.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYL"
BASE COUNT          337 a          152 c          116 g          324 t
ORIGIN      
        1 ttttataata ctgaattcgg aattaaaaac cacgataggt aactttaaac aaacatgaag
       61 agactttaat aagacttctt tatctgaaaa cacttttgtt tctctctttc ctttctacat
      121 cattaaatag tattttatac gttatctaaa atactattcc tctgtcaaaa taagctaact
      181 tacttcatta taaaatatcc acttatcgct ttcatgtata ttccaccgta aaaagtacat
      241 tttatcaccg agaactcatc atttttcatc atgatgaata ctatttacat atatctagtt
      301 caaagacaat aattattatg atccgttatt atctaagcac tatacagata ataggaattt
      361 ttcgtttcta aatattccaa tttgggaatc caataaaaat tttcgttcaa atacgtgtct
      421 attcgaactc ttttctagtt gttaattatg aagggggaag aaataaaaaa tacaatctat
      481 acacgaataa gaatattatc caaaaggagg ttttagaaaa gatttattat acgtaaaaag
      541 ctcaagacat tttcttagcc ataaggacat gtttgatatt taagaagata tatgaatttt
      601 cttttctaag tataaagata actatccatt atcaactaaa aaaacatttt tgaaaataaa
      661 catcagcagt cctatcaatg catgtgagct tatagaagtt attcgcagcg cagcataatt
      721 gcattagctt cttttcgtgt tttttgcctc ttttcccttt aaatcttaat ggaggaggtg
      781 tgcaatatgt cagataacga cgaacgcgta aatgcccagt tgattcgatt ctttgaaaag
      841 gtcattttga acaccgctaa tacttattat aaaaaacaag aagaaattca aaaacatgaa
      901 caacttgatc aactcccacc atatttgtt
//
LOCUS       DAFLWZ010000219          926 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000219 DAFLWZ010000000
VERSION     DAFLWZ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.229"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            6..>926
                     /gene="bsh"
                     /locus_tag="L1V38_003035"
     CDS             6..>926
                     /gene="bsh"
                     /locus_tag="L1V38_003035"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBN1317487.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSH"
BASE COUNT          319 a          124 c          169 g          314 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcat
//
LOCUS       DAFLWZ010000220          923 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000220 DAFLWZ010000000
VERSION     DAFLWZ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.230"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(71..475)
                     /locus_tag="L1V38_003036"
                     /pseudo
     CDS             complement(71..475)
                     /locus_tag="L1V38_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(534..>923)
                     /locus_tag="L1V38_003037"
     CDS             complement(534..>923)
                     /locus_tag="L1V38_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317488.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          275 a          163 c          153 g          332 t
ORIGIN      
        1 cacgacctaa agatcgtgtc taattatgac tgtatcagaa aatatgatac caaacggatc
       61 tattcattaa ttaattgaca tagtttatct gttgctcttt tatgactgga taactgacca
      121 attcatgacg atccaagtct tctttattca tatttacagc agtaatttga ctgtcttcat
      181 acgtacgata ataataaatc cctttatcaa cgttacagca agaagaataa atcgtatatt
      241 cgtattttcc ttctccagta tcgcatactc ctttttgttg ctcgactgag cctagtatat
      301 gaaaaaattg actgatactt tcagattctg aatcacctga tgcagcattc attttagtaa
      361 atgtggcttt tacaaatcga gaaacagaag agagatctcc aggtaagccc aatcctccca
      421 tcccacgact ataaacattc aagctgatct ggtttgaaaa atgattttct ggtgttccat
      481 tgggagcgtc aataattttg tgtaaataaa ttgtcctcct gcaaaataat tagttactca
      541 gtaaacattg aaactaatgt atcggttacc tgttgaaaac ctttatggct tctgtttaga
      601 aatttttgat tgtatgtatc aaaaatgctg actagaaagc gttctagtga ttcttcattt
      661 tgaaactgct cttttctacg gctgtatctt ttaatttgct tattgaaaga ctcgattaga
      721 ttggttgagt aaatggttct acgaatgcta ggtggaaaat cataaaaagt taataagtct
      781 tggttttcta tgagtgactg cgtcacttta ggatagtttt tcttccattt ctcaatcatg
      841 ccggataaga aggtattcgc ttcttctttt gagttagctt gataaacagc cttaaagtca
      901 tcacagattt cttttcggtc ttt
//
LOCUS       DAFLWZ010000221          895 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000221 DAFLWZ010000000
VERSION     DAFLWZ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.231"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..875)
                     /locus_tag="L1V38_003038"
     CDS             complement(<1..875)
                     /locus_tag="L1V38_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1317489.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTG"
BASE COUNT          301 a          107 c          156 g          331 t
ORIGIN      
        1 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
       61 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
      121 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
      181 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
      241 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
      301 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
      361 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
      421 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
      481 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
      541 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
      601 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
      661 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
      721 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
      781 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
      841 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatat
//
LOCUS       DAFLWZ010000222          857 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000222 DAFLWZ010000000
VERSION     DAFLWZ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.232"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..116
                     /locus_tag="L1V38_003039"
     CDS             <1..116
                     /locus_tag="L1V38_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBN1317490.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="L1V38_003040"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="L1V38_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBN1317491.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca agttttt
//
LOCUS       DAFLWZ010000223          842 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000223 DAFLWZ010000000
VERSION     DAFLWZ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.233"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>842
                     /locus_tag="L1V38_003041"
     CDS             <1..>842
                     /locus_tag="L1V38_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBN1317492.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLK"
BASE COUNT          367 a          108 c          136 g          231 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 tt
//
LOCUS       DAFLWZ010000224          811 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000224 DAFLWZ010000000
VERSION     DAFLWZ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.234"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            178..762
                     /locus_tag="L1V38_003042"
     CDS             178..762
                     /locus_tag="L1V38_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1317493.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          258 a          119 c          167 g          267 t
ORIGIN      
        1 tttttttcta attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc
       61 tttatttttc aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc
      121 agttaaacta tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg
      181 aaaataggat acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc
      241 ctaaataaat ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat
      301 cgaccaggat tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg
      361 cgcttagatc gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat
      421 gagcgtggtg tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct
      481 acaggacagc tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc
      541 ctggaacgat ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt
      601 cctgaaaaat tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca
      661 cctattaaga ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg
      721 gcaaaaatgg aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct
      781 gaaaattttt gccatttatc tagaaaagtg a
//
LOCUS       DAFLWZ010000225          797 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000225 DAFLWZ010000000
VERSION     DAFLWZ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.235"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..204)
                     /locus_tag="L1V38_003043"
     CDS             complement(<1..204)
                     /locus_tag="L1V38_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317494.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLT"
BASE COUNT          246 a          137 c          120 g          294 t
ORIGIN      
        1 tgtaagtact gttggtgtta atatagggac tttgtacaat tgtatttttt tgattttatc
       61 atctgcacaa aggagatttt ttaaatctaa tccttctttt atttcaaaag ttgaattttt
      121 taaatctata agagtaaaac caattccttc atactgaatt tctgaaaatc gaatttttct
      181 cccagttgat agatcaaggg gcagaaaacc ttttattaca ttgtgagtgt caccatcatt
      241 tacaatgtca ttaggaattt tgattttaga attctgtgga gcacctattg gaagataata
      301 attcattata attttgtagt cttcatgagg aaataaagta cttttaggat tgctaagata
      361 ttctcgtacc gaatctaaga atggcttatc cattgaatct tcatccccat ttaaactaaa
      421 aaacattcct acaattgctt ttgcaactct aagtgaattc attttcttta ttgaatgtgt
      481 taaatcagac ttaccattct ttaaacttgt attgttataa aggaaatttt tattgtcttc
      541 tgcaaatcta atatattcct caacatactc actaccaaaa aaactattac atttactaca
      601 taacgtattg gaatggcaac agtttttttg acaaatttta taaggtgcag aacttctttc
      661 cgtatgctat tccgattgtc cttgacaatg agcctcctcg gatgtgacga tcttcggcag
      721 gagctaacag ttaaagttag actgcctcgc tagcgttagc acatccgagc tcattatcaa
      781 ggattcgctg cgccaat
//
LOCUS       DAFLWZ010000226          765 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000226 DAFLWZ010000000
VERSION     DAFLWZ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.236"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(230..>765)
                     /locus_tag="L1V38_003044"
     CDS             complement(230..>765)
                     /locus_tag="L1V38_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1317495.1"
                     /translation="DYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGS
                     QWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPD
                     LPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDK
                     LLNRIDKEILKVGNIDE"
BASE COUNT          269 a          124 c           88 g          284 t
ORIGIN      
        1 aaaactaatc attgctccaa tcagtagcca agaaaaacgc attttaaaaa aatttttctt
       61 tataaaaacc tcatacaaaa ctataattcc accccaagca aaagctattt tcatcgggat
      121 attagttaca ttaaaagtac taggcataaa ataaagcaga caaatgatta aatttattac
      181 tcgaaacgca tctcgactta ataaactctt ctctaaaaca ggtactattc tattcatcta
      241 tatttccaac tttcaaaatt tctttatcaa ttctatttaa tagtttatca gagtaatccg
      301 atttaacttt tcttacaaat aatttttcac tttcttttat ttgatctata tccctttcat
      361 caaaccattt gttcatggaa ggatcaataa tatgaatatt tgctaatttc gaagtttgta
      421 aagtagtttc ttcaatattt ttcaattcaa gtggtaaatc tggtcctcca ataacatttt
      481 tatttttgaa cgaggaatta aaaaaaagtg tatgaaaaaa tttttcatct ggggcaaaca
      541 tacctatttt aaaattcagg tagtcttgtt gattttgttc atacatttgt attaattctg
      601 ttaggcattc tttcgacaaa gcccaccatt gagaaccatg atacaaatca aatttatggt
      661 gtctaatttt tgggggaagt ttaatcatcc tcagacaacg attaattata gctctaaaaa
      721 ttttaaatgc agttgtgtta ttcctattaa ttctaggata atcat
//
LOCUS       DAFLWZ010000227          760 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000227 DAFLWZ010000000
VERSION     DAFLWZ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.237"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>760
                     /locus_tag="L1V38_003045"
     CDS             <1..>760
                     /locus_tag="L1V38_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317496.1"
                     /translation="KEGKNIEENDKNSIIVHEEFAKQNNLKLGDEVDLELLDIEKSGK
                     IKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDYSTSQEILNNSENNEIANKILMY
                     SGSAESTDLALNKLKELKIDESKYFVEKDSNAFEESLESVSGIKYIIKVMTYSIMLGG
                     MVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQFIFELIFISIPSIISSLFLGNVL
                     LKVIVDGFINSEDSMISGGSLINNSSFMSNITTLG"
BASE COUNT          305 a           68 c          129 g          258 t
ORIGIN      
        1 taaagaaggt aaaaatatag aagaaaatga taagaattca attattgttc atgaagaatt
       61 tgctaaacaa aacaatctaa aattaggtga tgaagttgat cttgaattac tagatattga
      121 aaaaagtgga aaaataaaaa gtcataaatt taaaattata gggatctttt ctggtaaaaa
      181 acaggaaaca tatacaggat tatcttctga ttttagtgaa aatatggtgt ttgtagatta
      241 ttcaacaagc caagagatat taaacaattc agaaaataat gaaattgcaa ataaaatttt
      301 aatgtattct ggtagtgcag aatctacaga cttagcctta aacaaattga aagagcttaa
      361 aattgatgag tcaaagtatt ttgttgaaaa agattctaat gcgtttgaag agtctttaga
      421 gtcagtgagt ggaataaaat atataataaa agtaatgact tattctatta tgttgggtgg
      481 gatggttgtt ctttcattaa tcttgattct atggttaagg gaaagaattt atgaaatagg
      541 tatattctta tctattggaa catctaagat acaaattata atgcaattta tattcgagtt
      601 aatattcata tcgataccaa gtataatatc ttccttattt ttaggaaatg tattactaaa
      661 agtaattgta gatggattca ttaactcaga ggattcaatg atttccggtg gaagtttaat
      721 aaataatagt agttttatgt caaatataac aacacttgga
//
LOCUS       DAFLWZ010000228          695 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000228 DAFLWZ010000000
VERSION     DAFLWZ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.239"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(81..635)
                     /locus_tag="L1V38_003046"
     CDS             complement(81..635)
                     /locus_tag="L1V38_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1317497.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          208 a          144 c           69 g          274 t
ORIGIN      
        1 cttccgaaaa ttcagttatc ttcattaatc tcaccttcta agttttcatt atacacaaaa
       61 aatatatcct aatatctcaa ttagcctccc aatttaaaac cacgtaacga tgcccctatt
      121 tcatcttcag ttataccaat gtaccttttt gtaattgctt gcgagctatg attaaaaata
      181 aacattaagg tagcaatgtc tctagttttc ttgtagtagt gatacccaaa agtttttctt
      241 aatgtatgtg ttcctatatc atctcttcct aatttttctg ctacatctgc atatatctga
      301 tagacacgat cccttgttat atgtcgacct tgttgccgac ttggaaataa ccaatcattt
      361 tcttctttac cttcagtata taataaaatc tcttctctca aattatctat aaaaatcggt
      421 tttcgcttac ctgttttatg ttcaacaata ataggcttac ttttacctcg tatgtctcca
      481 acttttaatc ctataatatc tgacatacgt aacccattat tgattccaaa caaaaataaa
      541 aaactatctc tttctggatt acttgttctt cttagccaaa actgaaaatc ttgtatctct
      601 tcatttgtcc ttaacggttg tacattatag ctcactattg tttcccttct taaaaatatt
      661 ctgagttcat gattatatat atattttacc ataat
//
LOCUS       DAFLWZ010000229          646 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.240, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000229 DAFLWZ010000000
VERSION     DAFLWZ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.240"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
BASE COUNT          249 a           82 c           81 g          234 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaataag aactaaatag gaaaacgtag acgtaatttt
      121 ctacgttttc cttttcatat atattaaata ttacggaaaa ttatataaac taatttagtg
      181 ttttgtttgt aattcctaat tttgctccac ttttagataa tttttaggtc tatttaactc
      241 attagacatt ctatgctcat ttttctccaa atttgtttca actctttcgt acttaatttt
      301 gcgtatttga aaattcttct tttagagtac ttttattacg atactagtat gatatatatc
      361 tacagcaaac agttaaaatc ttcctaaaat aagcgaatag cattcctaaa acctataaaa
      421 tttttagatg aagcgacaag tggacaatta ataaactact tgaacatgaa attatggatc
      481 acctttcaaa tttagaaaat ggaattctta tacttattgc gcaacattta ttgattgcaa
      541 aattatgtga caaaaagaac tagtagaaga aggaataatg gcttgataat aaagtactac
      601 ctattaaagg tagtacttta tttaatttag tataaattaa catact
//
LOCUS       DAFLWZ010000230          573 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000230 DAFLWZ010000000
VERSION     DAFLWZ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.241"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
BASE COUNT          185 a           81 c           81 g          226 t
ORIGIN      
        1 tttttcttga tgtgatatcc ttgtcttttt tgtaatgttt ttaacttatt gcttttgcaa
       61 aatttattta cctgttttct ggatcaacga tagtgtacat tatgctatcc ttgtttggat
      121 tttaggacgt ttaaagaggc acttttttac ataacttaat ccatagacct tttaagcatg
      181 ctgtgagata ataataaaga agagtttaaa gcgcacccca aaccacttcc ccataagtgt
      241 attacgcttt aaactctttt atatttgaat tcactaagaa gcataccata tttttgaaaa
      301 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      361 aggactgata ctatagatta caaatagtat cgtatttcgc aatcttaaaa ttatcttctt
      421 actgtgaata agataataaa atttgtattt gtccttttta ggtaacttat tttaatctat
      481 atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat ggtaactatg
      541 cactgtaacg ataatgctgc taaaatatct ttt
//
LOCUS       DAFLWZ010000231          563 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000231 DAFLWZ010000000
VERSION     DAFLWZ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.242"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..281
                     /locus_tag="L1V38_003047"
     CDS             <1..281
                     /locus_tag="L1V38_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317498.1"
                     /translation="KQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEGFNKQLKR
                     YTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          201 a          100 c           64 g          198 t
ORIGIN      
        1 aaaagcagta tccaagagtc gtcaatttac tcttgaatcc tgccctatta accttttata
       61 atttccctca cgccatcaga cgaacaattt attcgacgaa cctgattgaa ggctttaata
      121 agcagctaaa acgatatact cgaagaaaag aacaattccc taatgaagaa tctctagaga
      181 gattcttcat ttctcaattt aatcaatata accaaaaatt tttaggtaga attcacaagg
      241 gatttaaaga aattcaggat acattagagt cgatgattta actgtaatta acagaatgga
      301 ttttccattt acatataatt cttgacgcta ccataatcta aataaccatc atattcatct
      361 actacttata taattgagtt ttattaaact ttttaagttt ctattctatc aaatatttaa
      421 acaatctctg catccgaaaa gactacctcg tatagtttta ctaacaatat ttttattagc
      481 gtgttcaaat cctgatttct tgtatcaatt attttctgtt cactttcaat aagaaaaaag
      541 tctttacttc catggataat aat
//
LOCUS       DAFLWZ010000232          549 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000232 DAFLWZ010000000
VERSION     DAFLWZ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.243"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            1..549
                     /locus_tag="L1V38_003048"
                     /pseudo
     CDS             1..549
                     /locus_tag="L1V38_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          212 a           94 c          105 g          138 t
ORIGIN      
        1 tacgtaaaag aaaccagcaa ttagaaatgg aaaatgatat tttaaagcaa gcagcgctga
       61 tattcggacg aagagacaag taatcgatgc gaataagcat ctttacccta tatcagcgat
      121 gtgcagaata ttaggtctat cacgtcagtc ctattattat caatcaaaac caaagaaaga
      181 cgaatcagaa cttgaagaag tagtcgctga agaatttatc cgcagccgaa aggcctacgg
      241 ctcaagaaaa ataaaaaaag ccttatcaaa acgaggcatt cagatcagcc gacgaaaaat
      301 tagtagaatc atgaaaaata gaggattaaa atcgagctat actgttgctt attttaaagt
      361 acatcattct acttgcaatg aagccaaaac gacaaacgta ttgaatcgta aattcttaag
      421 agacaaccca ttagaagcga tcgtaacaga cttgacttat gtacgagtcg ggaaaaaatg
      481 gaattatgtc tgtttcattt tggatctgtt caatcgagaa attctcggct attcttgtgg
      541 agaacataa
//
LOCUS       DAFLWZ010000233          548 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000233 DAFLWZ010000000
VERSION     DAFLWZ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.244"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..174
                     /locus_tag="L1V38_003049"
     CDS             <1..174
                     /locus_tag="L1V38_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1317499.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
     gene            complement(171..449)
                     /locus_tag="L1V38_003050"
     CDS             complement(171..449)
                     /locus_tag="L1V38_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317500.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
BASE COUNT          177 a           98 c           71 g          202 t
ORIGIN      
        1 catcgatcga taaaacgtcg acataaattg tatcaaagtc tacgtacagc ttccaccaca
       61 attaaaggga tggaaaccat tcgaggaatc tacaagaaaa gccgaaaaga aggcactctc
      121 ttcggctttt cagtctgcac tgaaatcagg atattattgg gaattccagc ttaaaatgaa
      181 gaaataatac aaaaactgat tttattttta aaactttgca gcagaaccct attttctaca
      241 atttgtttat taataacact ttgcccagag ctattattta cataagtagg aatcgcatta
      301 gtttcccatc gtataggcat caaaatcact tttgtattat ctgtattttc tatattccat
      361 ctatatatgg tttcttctac ttcattcctt tttgctgcta tatcacctgg tgatgctata
      421 aatactttta taagatttat ggttttcatt tattgtacct ttctctctag ttctctttaa
      481 agtaatttta gtataaaatt tattgtcttt tacactatag tacaaccttt atctatctag
      541 taaaaaaa
//
LOCUS       DAFLWZ010000234          534 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000234 DAFLWZ010000000
VERSION     DAFLWZ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.245"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>534
                     /locus_tag="L1V38_003051"
     CDS             <1..>534
                     /locus_tag="L1V38_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1317501.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAFLWZ010000235          527 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000235 DAFLWZ010000000
VERSION     DAFLWZ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.246"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..193)
                     /locus_tag="L1V38_003052"
     CDS             complement(<1..193)
                     /locus_tag="L1V38_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1317502.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKY"
     gene            complement(212..373)
                     /locus_tag="L1V38_003053"
     CDS             complement(212..373)
                     /locus_tag="L1V38_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBN1317503.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            443..>527
                     /locus_tag="L1V38_003054"
     CDS             443..>527
                     /locus_tag="L1V38_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317504.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
BASE COUNT          177 a          100 c           61 g          189 t
ORIGIN      
        1 aatatttacc atcttttttt gttattgata ttgaagaatt agaactttca tataaagcct
       61 tttctatttc attgcttgat ttcattattg ttaaacaaga atacaagcaa gaaagaacta
      121 tagttaatat gataaaaatt attaaagttc tatttttctt tcttgtaata tatgctatag
      181 cattttttat cactttccta actactcctt tctattttct tactccataa ctaattgcat
      241 ccactggaca agcattttta catcgtccac atctgataca ctccagatga ttgcaattct
      301 caactgaatc tttattcatt tggcaaactt ttttacattt tccacaatta atacacttat
      361 ccttatcctg aatcggctac actagactag acagaaaaaa taaggtgtgt agaataataa
      421 aaaacacact ggaggatttt tcatgccaag acgtcaacga agaacctatt caaaagaatt
      481 caaacaacaa atcgtcgatc tctatctcgc tggtaagcct tgcgcag
//
LOCUS       DAFLWZ010000236          527 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000236 DAFLWZ010000000
VERSION     DAFLWZ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.247"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            258..527
                     /locus_tag="L1V38_003055"
                     /pseudo
     CDS             258..527
                     /locus_tag="L1V38_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          181 a           94 c           76 g          176 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataac
//
LOCUS       DAFLWZ010000237          507 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000237 DAFLWZ010000000
VERSION     DAFLWZ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.249"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            55..>507
                     /locus_tag="L1V38_003056"
     CDS             55..>507
                     /locus_tag="L1V38_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1317505.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEK"
BASE COUNT          233 a           54 c           81 g          139 t
ORIGIN      
        1 gaaaataatt tttaataact tatttaagga aattttttga aggagaagat aaaagtgaga
       61 aaaaagatta ttattaatgc tggagtaatt ataggattga tgttagtaat tttctccgga
      121 aagcaatatg ctgataatat tttattatgg ggaggggaag ataatattga aaagatcaac
      181 aacaatttaa ctatattaga cacagctcta gaaaataaag agcaaaaaat tagtatttta
      241 aattcacaat tgtcttcaaa caaccaaact cttgaacaac taagaactaa tattgaagtt
      301 tccaaacaaa aagtggcatc tttagaaaac gacaagaatc aattagtatc agagaaaact
      361 aatttagaaa atcaattgtc agcaaaagac tctgaattgc aaggaaaaca aaatgaaatt
      421 aatgcgaaaa tagacgaaat taaccaaaaa gtagctgaaa taaatcgatt aaatagcgat
      481 tggaataatc gtttacaaaa tgaaaag
//
LOCUS       DAFLWZ010000238          503 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000238 DAFLWZ010000000
VERSION     DAFLWZ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.250"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            10..375
                     /locus_tag="L1V38_003057"
     CDS             10..375
                     /locus_tag="L1V38_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1317506.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
BASE COUNT          201 a           35 c           86 g          181 t
ORIGIN      
        1 gatgataata tggtttttga tattgataat ttaaaaggat ttcttaatga taccagttca
       61 tttgggttta tagctaaaga aaataataaa attataggat ttgcatattg ctatacactt
      121 ttaagacctg atggaaaaac aatgttttat ttacactcaa taggaatgtt acctaactat
      181 caagacaaag gttatggttc aaaattatta tcttttatta aggaatattc taaagagatt
      241 ggttgttctg aaatgttttt aataactgat aaaggtaatc ctagagcttg ccatgtatat
      301 gaaaaattag gtggtaaaaa tgattataaa gatgaaatag tatatgtata tgattatgaa
      361 aaaggtgata aataaatgaa tatagttgaa aatgaaatat gtataagaac tttaatagat
      421 gatgattttc ctttgatgtt aaaatggtta actgatgaaa gagtattaga attttatgat
      481 ggtagagata aaaaatatac att
//
LOCUS       DAFLWZ010000239          471 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000239 DAFLWZ010000000
VERSION     DAFLWZ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.251"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>471
                     /locus_tag="L1V38_003058"
     CDS             <1..>471
                     /locus_tag="L1V38_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317507.1"
                     /translation="AGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEE
                     ATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKD
                     TKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          191 a           70 c          112 g           98 t
ORIGIN      
        1 cgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga aagacggcgt
       61 aagcttacca gaagataaac ttccagtgtt gaaagcaaaa gatggttata cagatgcgaa
      121 atggccagag gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc
      181 aacaaaactg gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac
      241 tacagaattg aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc
      301 aaaagatact aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa
      361 agggactgtt gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac
      421 agtgacagac aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DAFLWZ010000240          468 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000240 DAFLWZ010000000
VERSION     DAFLWZ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.252"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>468
                     /locus_tag="L1V38_003059"
     CDS             <1..>468
                     /locus_tag="L1V38_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1317508.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAFLWZ010000241          464 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000241 DAFLWZ010000000
VERSION     DAFLWZ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.253"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>464
                     /locus_tag="L1V38_003060"
     CDS             <1..>464
                     /locus_tag="L1V38_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317509.1"
                     /translation="LVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSG
                     NSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVT
                     MSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          168 a           85 c           77 g          134 t
ORIGIN      
        1 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
       61 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      121 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      181 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      241 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      301 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
      361 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
      421 gccttaaatg ataagtatgt cgctattttt atggacgcta ctta
//
LOCUS       DAFLWZ010000242          462 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000242 DAFLWZ010000000
VERSION     DAFLWZ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.254"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..430)
                     /locus_tag="L1V38_003061"
     CDS             complement(<1..430)
                     /locus_tag="L1V38_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1317510.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DAFLWZ010000243          456 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000243 DAFLWZ010000000
VERSION     DAFLWZ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.255"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
BASE COUNT          148 a           89 c           52 g          167 t
ORIGIN      
        1 agcacaaaaa ataaaaaaat tattacgtta ttaaaaaaac agatgaaaga tcaggtttta
       61 ttagatctca ttctttcatc acttgaaggg atttaatgaa ctactttttc ctctttgtcg
      121 tttttatata ttcgtattcc ttcaaacagt aggatagcct ctttcaatgc ttgatatttg
      181 aactgtccgt tacttaaaaa tttagatgtg ccgccctctt cctagaacat attctttttt
      241 actttttcat taattgacag accaatcgaa cgaaactgta aatttcgata ggataatgat
      301 tggtcaaact cattcatttt caagacatct cgattcatat tcaagatagg aatcttttta
      361 tcaacatcac tttattcgta ttttcctcta ccataaaagc ttcacgctcc acaaaattgt
      421 tttatacact actattcagc ccattcaacg accaat
//
LOCUS       DAFLWZ010000244          406 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000244 DAFLWZ010000000
VERSION     DAFLWZ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.256"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>406
                     /locus_tag="L1V38_003062"
     CDS             <1..>406
                     /locus_tag="L1V38_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317511.1"
                     /translation="FICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLVMD
                     MNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRL
                     KRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTE"
BASE COUNT          128 a           96 c           71 g          111 t
ORIGIN      
        1 tttatttgtg ttgatgggac aaccaatcag ctatttacga tccttgaaga tcgcagactt
       61 tacaaactaa ctcaatactt cctgcgcttt cctagaaagg cccgtttaaa ggtcaagtac
      121 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
      181 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      241 cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg aaaatcagaa gaagtaccgt
      301 cggctcaagc gatattggaa actcttactc aaagattcca cgacattgga gccactcaaa
      361 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaa
//
LOCUS       DAFLWZ010000245          402 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000245 DAFLWZ010000000
VERSION     DAFLWZ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.257"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..348
                     /locus_tag="L1V38_003063"
     CDS             <1..348
                     /locus_tag="L1V38_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1317512.1"
                     /translation="VNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSD
                     APIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGK
                     KLKKVNKMNLEVE"
BASE COUNT          171 a           38 c           77 g          116 t
ORIGIN      
        1 gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa aaaacaaata
       61 aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat tgctagagca
      121 ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct agacagtgtt
      181 actgctggag aaataattaa tatattaaag acattagcta aagatagaaa taaatgtgta
      241 atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt agaactaagt
      301 ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg ataaaaaatg
      361 catttgctta tgtaactaga aaaagtttaa aatcattaat ta
//
LOCUS       DAFLWZ010000246          376 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000246 DAFLWZ010000000
VERSION     DAFLWZ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.258"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..197
                     /locus_tag="L1V38_003064"
     CDS             <1..197
                     /locus_tag="L1V38_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1317513.1"
                     /translation="NNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRN
                     GTLFGFSVSTEIKVLMGITA"
BASE COUNT          130 a           67 c           63 g          116 t
ORIGIN      
        1 ttaacaattt aatagaacaa gaccatcgac ctattaaacg acgaaataaa ttttatcaaa
       61 gtctccgtac agcctcttcc acgattaagg gcatggagac cattcgagga atatataaaa
      121 agaaccgaag aaatggaacg ctcttcggct tttcggtgtc tactgaaatc aaggtattaa
      181 tgggaataac agcctaagat atttggagtt cagagagggc gcgtttgatt ttcaaacttc
      241 gcaacagaac caaaaaattg gtttaattgt tctgtactag gttctcctaa ataaatgcca
      301 aatgcttttt tgttactttt gatttcatcc atttaaaccc tccatgaagt aaattttaag
      361 tctacataaa atttat
//
LOCUS       DAFLWZ010000247          375 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000247 DAFLWZ010000000
VERSION     DAFLWZ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.259"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..>375)
                     /locus_tag="L1V38_003065"
     CDS             complement(<1..>375)
                     /locus_tag="L1V38_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317514.1"
                     /translation="PYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQANME
                     EEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTPQKVG
                     VNYPKRLTIIQYPQSTTGACQID"
BASE COUNT          100 a           73 c           80 g          122 t
ORIGIN      
        1 gtcaatttga catgcacctg ttgttgattg gggatactgg ataatagtta accgtttggg
       61 gtagttaact ccaaccttct gcggtgtaaa agtcagaccc catgtatcaa ctaacccttc
      121 tactggctct aagttaccat atctataatc tccactatcc tcgttgtaaa caatgaacgt
      181 ttggataggt ggtttggttg ccttcatggt aattgtatag gtttgaccta aaacaaattc
      241 ttcttccatg ttagcttggt ataggctgta ggcgctagat ttgattggaa acgtaacaga
      301 cttattagca atattctcac ccaaaggcgc tttacctagc cagtaagggt catcaagtaa
      361 gtttggctga tatgg
//
LOCUS       DAFLWZ010000248          354 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000248 DAFLWZ010000000
VERSION     DAFLWZ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.260"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>354
                     /locus_tag="L1V38_003066"
     CDS             <1..>354
                     /locus_tag="L1V38_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBN1317515.1"
                     /translation="FIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPILIDQA
                     SEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITKTSPYN
                     KTDEENFHLIVTTLQ"
BASE COUNT          142 a           50 c           47 g          115 t
ORIGIN      
        1 cgtttatcga atctattgat tctacaatcg atagattaaa aaaagaaatt cgattttata
       61 atagagtaat tggtatcgga aatattataa aaatagtctt atcagctagt atcccaatat
      121 taattgatca ggcttccgaa cacaggtctt tactattgat tgtttcaatt gcttcagcaa
      181 taattacaat tatacaaagt ggtatgtctg catttaatta tcaagataaa gtacagactt
      241 cgacagagtt attaatgaaa attgaaaaag aaaagttgtt atatataacg aaaacatccc
      301 catataataa aacagatgaa gaaaatttcc atttaatcgt tacaaccctt caaa
//
LOCUS       DAFLWZ010000249          321 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000249 DAFLWZ010000000
VERSION     DAFLWZ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.261"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(69..321)
                     /locus_tag="L1V38_003067"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="L1V38_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFLWZ010000250          305 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000250 DAFLWZ010000000
VERSION     DAFLWZ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.262"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1V38_003068"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1V38_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBN1317516.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DAFLWZ010000251          299 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000251 DAFLWZ010000000
VERSION     DAFLWZ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.263"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..>299
                     /locus_tag="L1V38_003069"
     CDS             <1..>299
                     /locus_tag="L1V38_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317517.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DAFLWZ010000252          288 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000252 DAFLWZ010000000
VERSION     DAFLWZ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.264"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
BASE COUNT          105 a           25 c           50 g          108 t
ORIGIN      
        1 aatcttaaca gatatttcat tttatttatg taaaacaaca cgaataatta ttgcttcgta
       61 aagttatatg agtataagtt aatttactgg aggtagtgca atgctttttt ctgaaagatt
      121 tggttttaaa aaatggagga tatcatactg agagatagat tgacagaccc tcttaaaaat
      181 agtttagcaa atgtgattta tgatatatta cgagaggctg ataaagttta tagtaattat
      241 aatggaaaag tctcatgggt aatatattct tttttaatta aagagttt
//
LOCUS       DAFLWZ010000253          278 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000253 DAFLWZ010000000
VERSION     DAFLWZ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.265"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            91..>278
                     /locus_tag="L1V38_003070"
     CDS             91..>278
                     /locus_tag="L1V38_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBN1317518.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILI"
BASE COUNT           85 a           49 c           53 g           91 t
ORIGIN      
        1 agactgtaga caaagtccat tttatggatg atgtctacag tcttttcttt tataatagat
       61 ttatgaaaac gaatgcaagg agtgatagct atgatgtcta aaaacaatac gaatggtaga
      121 aatcaatttg cgatgcttac gattgatgat ctagttcctc aagatcatct cgttcgaaag
      181 attgatgccg cgcttgattt tgaatttatt tatccaatcg tcgaagccac ttactccgat
      241 ttaggtcgcc caagtatcga tccagtgatt ctgatcaa
//
LOCUS       DAFLWZ010000254          267 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000254 DAFLWZ010000000
VERSION     DAFLWZ010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.267"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(35..>267)
                     /locus_tag="L1V38_003071"
     CDS             complement(35..>267)
                     /locus_tag="L1V38_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317519.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          103 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaata
//
LOCUS       DAFLWZ010000255          253 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000255 DAFLWZ010000000
VERSION     DAFLWZ010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.268"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            28..>253
                     /locus_tag="L1V38_003072"
     CDS             28..>253
                     /locus_tag="L1V38_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1317520.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DAFLWZ010000256          246 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000256 DAFLWZ010000000
VERSION     DAFLWZ010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.269"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            32..>246
                     /locus_tag="L1V38_003073"
     CDS             32..>246
                     /locus_tag="L1V38_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1317521.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQN"
BASE COUNT          108 a           25 c           43 g           70 t
ORIGIN      
        1 aatcttatca aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc
       61 atatagttat gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact
      121 tgggaagttt tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt
      181 acttgctgga cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca
      241 aaataa
//
LOCUS       DAFLWZ010000257          241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000257 DAFLWZ010000000
VERSION     DAFLWZ010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.270"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..220)
                     /locus_tag="L1V38_003074"
     CDS             complement(<1..220)
                     /locus_tag="L1V38_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1317522.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAFLWZ010000258          233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000258 DAFLWZ010000000
VERSION     DAFLWZ010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.271"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DAFLWZ010000259          227 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000259 DAFLWZ010000000
VERSION     DAFLWZ010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.denovo.272"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(<1..>227)
                     /locus_tag="L1V38_003075"
     rRNA            complement(<1..>227)
                     /locus_tag="L1V38_003075"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           48 a           77 c           45 g           57 t
ORIGIN      
        1 atcgtctgca ttccttagcc tcctgcgtcc ctccattgct caaacaaaaa caacgggtac
       61 aggaatatca acctgttatc catcgcctac gcctgtcggc ctcggcttag gtcccgacta
      121 accctgggcg gacgagcctt ccccaggaaa ccttagtcat tcggtggaca ggattctcac
      181 ctgtctttcg ctactcatac cggcattctc acttctaagc gctccag
//
LOCUS       DAFLWZ010000260        13213 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.070, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000260 DAFLWZ010000000
VERSION     DAFLWZ010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.070"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(204..2162)
                     /locus_tag="L1V38_003076"
     CDS             complement(204..2162)
                     /locus_tag="L1V38_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1317523.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="L1V38_003077"
     CDS             complement(2159..3031)
                     /locus_tag="L1V38_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1317524.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="L1V38_003078"
     CDS             complement(3373..4245)
                     /locus_tag="L1V38_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1317525.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="L1V38_003079"
     CDS             4373..4942
                     /locus_tag="L1V38_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1317526.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="L1V38_003080"
     CDS             5009..5746
                     /locus_tag="L1V38_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1317527.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="L1V38_003081"
     CDS             5977..7245
                     /locus_tag="L1V38_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1317528.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="L1V38_003082"
     CDS             7732..8196
                     /locus_tag="L1V38_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1317529.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="L1V38_003083"
     CDS             8180..8809
                     /locus_tag="L1V38_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1317530.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1V38_003084"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1V38_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1317531.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="L1V38_003085"
     CDS             10688..11134
                     /locus_tag="L1V38_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1317532.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="L1V38_003086"
     CDS             complement(11333..11848)
                     /locus_tag="L1V38_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1317533.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="L1V38_003087"
     CDS             11965..13167
                     /locus_tag="L1V38_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1317534.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAFLWZ010000261        12791 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.072, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000261 DAFLWZ010000000
VERSION     DAFLWZ010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.072"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            complement(134..577)
                     /locus_tag="L1V38_003088"
     CDS             complement(134..577)
                     /locus_tag="L1V38_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBN1317535.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="L1V38_003089"
     CDS             complement(795..2135)
                     /locus_tag="L1V38_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1317536.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="L1V38_003090"
     CDS             2404..3300
                     /locus_tag="L1V38_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1317537.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="L1V38_003091"
     CDS             complement(3450..4391)
                     /locus_tag="L1V38_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1317538.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="L1V38_003092"
     CDS             4517..5638
                     /locus_tag="L1V38_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1317539.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="L1V38_003093"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="L1V38_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1317540.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="L1V38_003094"
     CDS             7426..7992
                     /locus_tag="L1V38_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1317541.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="L1V38_003095"
     CDS             8203..9264
                     /locus_tag="L1V38_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1317542.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="L1V38_003096"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="L1V38_003096"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1317543.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="L1V38_003097"
     CDS             10177..12159
                     /locus_tag="L1V38_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1317544.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="L1V38_003098"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="L1V38_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1317545.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         4211 a         2335 c         2654 g         3591 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata t
//
LOCUS       DAFLWZ010000262         7497 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.106, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000262 DAFLWZ010000000
VERSION     DAFLWZ010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.106"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..441
                     /locus_tag="L1V38_003099"
     CDS             <1..441
                     /locus_tag="L1V38_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317546.1"
                     /translation="VLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSL
                     KDLSAPNSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVI
                     NRDERRDVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            445..648
                     /locus_tag="L1V38_003100"
     CDS             445..648
                     /locus_tag="L1V38_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1317547.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(948..1184)
                     /locus_tag="L1V38_003101"
     CDS             complement(948..1184)
                     /locus_tag="L1V38_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1317548.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(1367..1753)
                     /locus_tag="L1V38_003102"
     CDS             complement(1367..1753)
                     /locus_tag="L1V38_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1317549.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(1735..3063)
                     /locus_tag="L1V38_003103"
     CDS             complement(1735..3063)
                     /locus_tag="L1V38_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1317550.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(3024..3353)
                     /gene="mobC"
                     /locus_tag="L1V38_003104"
     CDS             complement(3024..3353)
                     /gene="mobC"
                     /locus_tag="L1V38_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1317551.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(3611..3981)
                     /locus_tag="L1V38_003105"
                     /pseudo
     CDS             complement(3611..3981)
                     /locus_tag="L1V38_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            4126..4311
                     /locus_tag="L1V38_003106"
     CDS             4126..4311
                     /locus_tag="L1V38_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1317552.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            4469..4636
                     /locus_tag="L1V38_003107"
     CDS             4469..4636
                     /locus_tag="L1V38_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317553.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            5254..5913
                     /gene="vanR"
                     /locus_tag="L1V38_003108"
     CDS             5254..5913
                     /gene="vanR"
                     /locus_tag="L1V38_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1317554.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            5916..7277
                     /gene="vanS"
                     /locus_tag="L1V38_003109"
     CDS             5916..7277
                     /gene="vanS"
                     /locus_tag="L1V38_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1317555.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(7368..>7497)
                     /locus_tag="L1V38_003110"
     CDS             complement(7368..>7497)
                     /locus_tag="L1V38_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1317556.1"
                     /translation="IENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         1866 a         1787 c         1890 g         1954 t
ORIGIN      
        1 gtgctgcagg aggcgctacg gacggagcag cacagccggg ggcgggccgt ccccggcgat
       61 ttcaaagtcc acgtcaccgc tttgcatgac agccggattg aaaccgaggc ccggcgtatt
      121 gtggacagcc tgaaagatct gtccgcgcct aacagcccca ataaaacgca tttcatggtg
      181 gagatctccc cgcactttgc ggcgattgct tccaccaagg ataatgaccg gctctttgcc
      241 atgctgccct ataaatccct gtgttttacc gggatgaaag gcaggcatgg cgtgtatgcc
      301 gtgattaacc gggacgagcg ccgggatgtg agtattcgca ggccccggcc ctctatccgc
      361 aagcagctat ccgacagcaa acaggccgcc agcccaaaaa aggcggcggc cagaaccaaa
      421 aagaatgaat tggaggtata aggaatgatg cactttaccg tggaggaaga aaacctgatc
      481 tgtatgtacc acaatgcaga ccggcgcaga acgataaaca ggctcaccgc cgtcatgccg
      541 gttatggatg gggatatgcg ggcgcaggcc cagcagaccc tttccaagct ggaacgcatg
      601 acggatgccg actatgacgg ccagaagttc cacttcacag acgaataacg aacagcagac
      661 gccgggcgcg gcggccatgt ggtcgcttgc gtccggcgtc ttttcttttt gcctattcct
      721 acgcatttag aacccggtat tgtcggggat aggatgaagt attcgcttgc ccctgcaaac
      781 atgcgggaga agccttgcag cgggcggttt tcaatccctt aaatgcgtag gttgcagcta
      841 taattagacc cctgaaacag atatagccgc gcagcgggtg tatctgtttc aggggtgtgc
      901 aggtgatagc cgcaaagcgg cgtaagaggg tgcagccctc ttgccgtcta tctctgttcc
      961 agcgggaagc tcggcaatgc ttccagcagt ttcagggaaa tgcgctgccg tatatcttcg
     1021 tcaatgactt tcttcttttt gccgtttgcc tgtctgatct ccaccgtgga aagctcgttg
     1081 atgtagtcag cataatgggc caacactttt tccgtggccc acctctcacc ggcaacggcg
     1141 gctttgatcg tttcatagtc cagcagcttt tcttgtccgt ccatcctgat acccccgtca
     1201 gactgatttt ttctatgata ccatattcgg aagcatggaa ccagagaaaa cggcgctttt
     1261 ctgctggtaa attctacgca tttagaacag cacttcggcg gggataggat aaaacaccca
     1321 cataccccgc tgaccatgcc ggaaaagcct tgaaatataa gggcttttac agctctaagt
     1381 gcgtaggttt ccagtatctt ttccgctggc gctcggcctc tttgcggcgg cgcatccgtt
     1441 tggagcaggc cgcgcagtat ttggcccggt tagacttcgg cgtgaacgtg gccccgcact
     1501 cacagcagcg tttcacttcg tcccggtctt tggtgatctc ggcatacagg gccgcatcca
     1561 gcgggaggac agcggcctta aaccagcggc acagaagcga ataggaaatg ctctgtacgc
     1621 aaatacattc ttcgccgtcg tccagcaaca ggcagttgcc gtcacaatag ttgcagcact
     1681 catgcgtcag cttccgggcc ttgcgatatt gagggtaatt cattcgtgga atactcatag
     1741 ctcttgcgtc cattcctttc ccggcgtcat acgcaaaatg ccgtccacat tctgcttgat
     1801 gatgccgtat tcctgcatct gctttttcgc ttcgccgtac ttctcataca gccgttcctt
     1861 ttcctcggcc aatcgcttgt actcggcttt cagggcgtac agatcgggga gctttttcac
     1921 accctgtccc tttagggcct ttgccgcagc ttcatacaaa atcaacgtgc tttcatgctc
     1981 acgccggaat tttgccttat ccgctgcatt gcggtattcc atagccacgg gccagagctg
     2041 cttgtaggta gaaatattct ttatcagcac cgccatatcc gcaagccggt gttccatagc
     2101 tttgagggta gcggcggcct cgtcgctggc ggcggtgatc tcggccactt tgctttccaa
     2161 atccgggtag gtgtctatcc catgttcagt caggaaattc aaagtctttg cggcctgctt
     2221 caaattgtgg agcttcgccc acctctcata gcctgccgac tgctgggcct taatgttgtt
     2281 ttccagatca atccgcaaag aaatcccctt gcgctctttg ggcgctctgg tgataacgcg
     2341 gcctttgata cgctctttga tggcttcctc ggtgtaggct tcccccaatg tcttgcagcg
     2401 ggtaaagcgt tcctgtccgg gagcgcggaa agaaataaac tttcccggct tgatctcata
     2461 gccctgcgcc tgcatgagcc gcaggaaatc atcaaaatct tttgcctgcg ggatagcggc
     2521 gtcaatggct gctttgagct tcgctttcca gctcgtccct ttccgctggg cgtcccactc
     2581 ggcatagctc ttgcccttac tctggccggg cttcaccacg gacaatccgt tttccttgca
     2641 cagcctgtcg ctggtgcgcc ggatataggc atagctctgt ttgttggaaa tgtacttgcg
     2701 ctgatttacc atatccacgg cacagaaaat aatgtgattg tggacgtggc ccttatcaat
     2761 atgggtagtc agcacatagg gatatttccc ttgcagcact tcctcggcaa gctgcttccc
     2821 gatctcatgg gcctgttccg gcgtggcttc gccgggggca aaggattgta tcaggtggtg
     2881 gcccagatta ttgccctttt ggtatgcctg cgccagcagc atttcaaatt caatgtccgc
     2941 tgtttcataa gagcaggcaa aggaggccac cagcagcttg ccgtcagttt tgtccgggtt
     3001 ctcgatgtag tcaagggctt ttttcagcgt tgacttgata ggatgtatct ttgtaactgc
     3061 catatctgcg ccagcgcccc ctttatatcc tcgatgtcct gtgcgtacac cggccccata
     3121 ccgttcagcc tctttgcaat ctgattgacg ttgacgccga tcttctgtat ctcggcggtc
     3181 tgcgcccgga tgtcgctggt gtccatgttg acgatatagc cgtcaatgag catcttccgg
     3241 gcgtaggctg aaaagttctt cgtatgcagc agcgccattt tctgttcaat catagcccgt
     3301 tcctccggcg tcacagggac gcgcagcacg atttttcgct ttctgtttgc catgcttcac
     3361 cgtcctttcc attcaggggt ttggggattt ccccaacaag caaaacggac gcggcccggc
     3421 agggacgggg caggccgttt ttccgggagt ggctacactc cctatgcttg ctacgttact
     3481 gtttctccac taacaagacg tttccaaagc cccaaactac ccgcaaaata gccctctgga
     3541 aagaaaaaag tgcaaaaaaa tagaagctac gctgtgcagc tcccgctaaa agtaaaacag
     3601 aggatgccag ttacacatcc tccgtttcat tcttcttcgg cttttcaatt agtatggcgc
     3661 tgtcaatcgc gccctcgatg atcggcaggt attcttcggg gcagagtttc agcttgtggc
     3721 tgaccctttg ccgcagttcg ctttcctccc gcatgatctc cgggttaaag tagcgttcca
     3781 caggaagccc gcaggcttta ataagctgta tgacaaccgg cagactggga atggcccgtc
     3841 gttttcgatg ttggcaagat agcgccagtc aatatttatt ttctctgcca ttgctttgcg
     3901 cgaaacgcgc tttgcttgcc gggccgcttt cacatccgcg ccgaaagttt caaagccggg
     3961 acaatcttca atattcgcca tatcgcacct cccacttaca ttgtatattt catactctgc
     4021 ccgtggaatg ttggtatatg cacctttctt aaagtttata tttcacattt tgtttctttt
     4081 attcttcgag caaaagaatt ataatgtacc ctgtggaggt gtactatgga ctacatgacg
     4141 ttgaaagagg caggcgagaa atggggtgtg cccccacgat ggataaacta ctattgtgct
     4201 gcgggacgca tccccggcgc tgtaaagatg gcgacgatct ggctcattcc caaaactgcg
     4261 gaaaagccga ttgacaggcg tacaaagaaa ggaaaggcgg ttactgaata gtataatgaa
     4321 accggcgcat tttggatatg gttttgaaga gagagaaagc atggtatttt gtcacggaaa
     4381 aactataaga tgatagatgg caggctgctc cagaccgata aaaagtattc tcatctgaaa
     4441 cagaaagaaa agatttacac atggatgtat gaagaagcga aactttatca tgacagaaat
     4501 ggaaaatgcc cgaaacaaag acgaggaagc tgctgctgta tcagccgtat atggtagaat
     4561 tgaaaaggcc ggcatctgga ttctttatgg tgaagtctcc agacattgga taactgctgg
     4621 tctaatgcgc ctttgagtat ggggtgattg attttaatac cggggaggta cggctttttg
     4681 aggaaaatat tctgggattt acatttggcg attattacat ttcctgtaac tgcaaggaca
     4741 cggatgatga agatatgagg aatatagact tgctgatttt ctactgtctt gaacggtatt
     4801 aggactgaat ctgctgcgcg gagtgcggca agagcgaccg gagggagtac acacaggccc
     4861 tgcctgtgtg aaaagccata ccgcaaggtg cattcgcaaa aaagaggccg cgcattttgc
     4921 tgaggcttgg ggtgtcccca acaagcaaaa cgagaacgcc gcaggcgggc aagtggtgga
     4981 tcagaatatc cgtaaaggat attctgatcc attgcttgcc agtattatcg ggatgttttg
     5041 acaaccgctg taatcgaaac atcccaaaca ttaagaaggt gttaattatt attatcttga
     5101 tttaattcgt ttaaaccaat aatatagata catacaccat gaaaagaagc gagtatccca
     5161 atgacggatg attaaaatcc gaaaagaaat cgctttgaaa ctacagggaa actacagact
     5221 gttatgttat cttcttaaaa tggagggatt tttatgtcga tacgaattct acttgtcgag
     5281 gatgatgatc atatctgtaa tacagtaagg gcgtttctgg ctgaggcagg atatcaggtg
     5341 gatgcctgca cagatggaaa tgaggcatac accaagtttt acgaaaacac ttatcaactg
     5401 gttattcttg atattatgct gcccggtatg aacgggcatg aacttttgcg tgaatttcgt
     5461 gcgaaaaatg atactcccat tctgatgatg acagccctgt cggatgacga aaaccaaatc
     5521 cgggcgtttg atgcagaggc agacgactat gtaacaaagc cattcaagat gcagatttta
     5581 ctaaagcggg tggaagccct gctgcggcgc agcggtgcgc tggcaaagga aatccgtgtc
     5641 ggcaggctga cacttctgcc ggaggatttc acggtacttt gtgacggtac agagctgccc
     5701 ctgacacgaa aagaatttga aatccttttg ctgctggtgc agaacaaagg cagaacctta
     5761 acgcatgaaa tcattttgtc acgtatatgg ggatatgact ttgagggtga tggcagcaca
     5821 gtccacactc atatcaaaaa tttgcgggcc aagctgccgg aaaatatcat caaaaccatt
     5881 cgcggtgtag gataccgatt ggaggaatca taataatgga aagaaaaggg attttcatta
     5941 aggttttttc ctatacgatc attgtcctgc tactgcttgt cggtgtaaca gcaacactgt
     6001 ttgcacagca atttgtgtct tatttcagag tgatggaatt acagcaaaca gtaaaatcct
     6061 atcagccatt ggtggaactg attcagaata gcgataggct tgatattcaa gaggtggcag
     6121 ggctgtttca ctacaataac caatcctttg agttttatat tgaagataaa gagggaagcg
     6181 tactctatgc cacaccaaat gccaatacat caaatagttt tagacccaac tttctttatg
     6241 tggtacatag agatgataat atttcgattg ttgctcaaag caaggcaggt gtgggattgc
     6301 tttatcaagg gctgacaatt cggggaattg ttatgattgc gataatggtt gtattcagcc
     6361 ttttatgcgc gtatatcttt gcgcggcaaa tgacaacgcc gatcaaagcc ttagcggaca
     6421 gtgcgaataa aatggcaaac ctgaaagatg taccgccgcc gctggagcga aaggatgagc
     6481 ttggcgcact ggctcatgat atgcattcca tgtatgtcag gctgaaagaa accatcgcaa
     6541 ggctggagga tgaaatcgca agggaacatg agttggagga aacacagcga tatttctttg
     6601 cggcagcttc tcatgagcta aaaacgccca tcgcggctac aagcgttctg ttggagggaa
     6661 tgcttgaaaa tatcggtgac tacaaagatc attctaagta tctgcgcgaa tgcatcaaaa
     6721 tgatggatag gcagggcaaa atcatttccg aaatactgga gcttgtcagc ctgaatgatg
     6781 ggagaatcgt acccatagct gaaccgttgg acatagggcg cacggttgcc gagttgctgc
     6841 ccgattttca aaccttggca gaggcaaaca accagcggtt cgtcacagat attccagccg
     6901 ggcaaattgt cctgtccgat ccgaggctgc tccaaaaggc actatccaat gtcatattga
     6961 atgcagttca gaacacgccg cagggaggcg aggtacggat atggagtgag cctggtgctg
     7021 aaaaatgccg cctttttgtt ttgaacatgg gcgttcacat tgatgatact gcgcttccaa
     7081 ggctgttcac cccattctat cgcattgatc aggcgcgaag cagaaaaagt gggcgaagca
     7141 gaaaaagtgg gcgaagcggt ttaggacttg ccatcgtaca aaaaacgctg gatgccatga
     7201 gcctccagta tgcgctggaa aacacctcgg atggcgtttt gttctggctg gatttaccgc
     7261 tcacatcaac attgtaaata tttaaaactt aaatgatttt gggctctttg tcaaatagga
     7321 ctgatagagt gagataagaa catctaaggt agaattcctt ttctacttta gatgtttttt
     7381 gattcatagg taatcagatt atttagtaag aaaattctgg tcttcatttt ccgaaagctt
     7441 cgaaagccat aagcgactcg tttcaatgct ttgatgtggg tatgcagatt ttctatt
//
LOCUS       DAFLWZ010000263         6186 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.116, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000263 DAFLWZ010000000
VERSION     DAFLWZ010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.116"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            74..2428
                     /locus_tag="L1V38_003111"
     CDS             74..2428
                     /locus_tag="L1V38_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1317557.1"
                     /translation="MLTIGVGFALILFAVFGFLKLGFLGILIANGFRIIAGNTYQILC
                     LLLAVLGFWIVIKNTEFSIGKNRRWFGGILFYFGILLLLHAHLFGKLHTGEPNIMGTT
                     WDLLASDIKQSQVDNNVGGGMIGAILYHFTYFLIAQPGSYLAAVLLLAGGAFLFSNLE
                     GYQLLNGIQSIGERVQELLEGDPAKQARKQAAKEERMKQRAEAKEARRLAAKEAAEYE
                     KKKAVSQQRENTADEWQEPENTEPEQLSFVPIDSFQENIHPANLEKPVPDTPKQTNTA
                     EGFSDELPEDDGTSLEFEIEAEQENQDYELPTVDLLDSIPTVDQSDEYKKIEKNIGVL
                     EQTFQSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEA
                     PIPGKSLIGIEVPNGKISMVSFREIIEAQPNHPDKLLEVPLGRDVSGRVQTADLSKMP
                     HLLVAGSTGSGKSVAINGIITSILMRAKPHEVKLMMIDPKMVELNMYNGIPHLLTPVV
                     TNPRKAAQALQKVVQEMEERYEKFAATGVRNISGYNEFVQQKNLENGTKHPTLPFIVV
                     IVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRM
                     AFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLPMGENKPIRVQGAFISDHEVERVVQFV
                     TDQQEAHYEEKMMPTDEVETTGAPEQPQDELFEEAKALVVEMQTASISLLQRRFRIGY
                     NRAARLVDELEAHGVVGPSEGSKPRKVFIEQEETSETLPDDNDM"
     gene            2658..3725
                     /gene="rlmN"
                     /locus_tag="L1V38_003112"
     CDS             2658..3725
                     /gene="rlmN"
                     /locus_tag="L1V38_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1317558.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(3918..5021)
                     /locus_tag="L1V38_003113"
     CDS             complement(3918..5021)
                     /locus_tag="L1V38_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1317559.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5573..6121
                     /gene="aac(6')"
                     /locus_tag="L1V38_003114"
     CDS             5573..6121
                     /gene="aac(6')"
                     /locus_tag="L1V38_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1317560.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2057 a         1069 c         1333 g         1727 t
ORIGIN      
        1 acaaaagaaa cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca
       61 gcagcaggaa caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt
      121 cggcttttta aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc
      181 aggaaatact taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat
      241 taagaataca gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta
      301 tttcggtatc ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc
      361 aaatatcatg gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga
      421 caataacgtt ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat
      481 tgcacagcct ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt
      541 cagtaatctg gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca
      601 ggaattattg gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag
      661 aatgaaacag cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga
      721 atatgagaag aaaaaagcgg tgagccagca aagggaaaat actgctgatg aatggcagga
      781 accagaaaat acagagccgg agcagctaag ttttgttcca atcgacagtt ttcaagaaaa
      841 tatccatcct gcgaatctag agaaaccagt accagataca ccaaaacaga ccaatacagc
      901 agaaggtttt tcagatgagt tgccagagga tgacggtacc tcattagaat ttgagattga
      961 agcagaacag gaaaatcaag actatgaatt accgacagtt gatttgcttg attctatacc
     1021 aactgtggat caaagtgatg agtataaaaa aattgaaaaa aatatcggcg tattagaaca
     1081 aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag gaccatccgt
     1141 cacaaaattc gaagtccagc cggctgtagg ggtaaaagta agtaaaattg tgaacttaac
     1201 agatgatatc gcgcttgctt tagcggcgaa agatgtccgg atggaagcac cgattccagg
     1261 taaatcactg attggtattg aagtaccaaa tggaaagatc agtatggttt cctttagaga
     1321 aatcatcgaa gcacaaccaa accacccaga taaattacta gaagtacctt taggacgtga
     1381 tgtttctgga cgggtacaaa cggctgatct ttcgaagatg cctcacttac tcgtggctgg
     1441 ttcgactggt agtgggaagt cagtagcaat taatgggatt atcacaagta tattaatgcg
     1501 tgctaagccc catgaagtaa aactgatgat gatcgatccg aaaatggttg aattgaatat
     1561 gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa aagcagcgca
     1621 agccttacaa aaagtagtac aagaaatgga agaacgatat gaaaaattcg cggcaaccgg
     1681 agtaagaaat atttctggtt acaatgaatt tgttcaacag aaaaacttgg aaaacggaac
     1741 gaaacatcca accttaccat tcatcgtagt gatcgtagat gaattagctg atttgatgat
     1801 ggtagccagc aatgaagttg aagatgcgat tattcgttta gcgcaaatgg ctcgggcagc
     1861 ggggattcat atgatcctag ctactcaacg tccaagtgtg gatgttatca caggaatcat
     1921 caaagcaaat gtaccttcca gaatggcatt tgcggtatca agcggtacag attctcggac
     1981 gatcattgat tctaatgggg cagaaaagct cttagggcga ggagatatgc tattcttgcc
     2041 aatgggtgag aataaaccga tccgtgtgca aggagcattc atttctgacc acgaagtaga
     2101 acgggtcgtt caatttgtta cagatcagca agaagctcat tatgaagaga aaatgatgcc
     2161 gacagatgaa gttgaaacga caggtgctcc agaacagcca caagatgagc tgtttgaaga
     2221 agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc aaagaagatt
     2281 tcggatcggt tacaaccgag cagcacgttt agtagatgaa ctggaagctc atggagttgt
     2341 tggcccgtca gaaggaagca agcctcggaa agtattcatt gagcaggaag aaacatcaga
     2401 aacgttgccg gacgataatg acatgtaaaa cttgtgtgat gaagggttga aaaacgaata
     2461 accaataaaa agacaaggca tgatgatacc aaaagaaaaa atggtttttt tccatctttt
     2521 ctaatacggt atgatgtctt gtctttttag tttttgtgag attaaagttc tattcgattt
     2581 atttgtgaag tattgcatta aggaaatgaa tcatgtatag tatgtagcga aactttgaga
     2641 aaaagaggga aaatactttg gaaaaacagt ccatttatgg cttgacgaat gaagaattaa
     2701 tcaattggtt tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt tgggaatggt
     2761 tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa caattgatcg
     2821 aaaaattatc ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc caagaagctt
     2881 cggatggtac agtaaaatat ttgtttgaac tccctgataa aaacatgatt gagactgtac
     2941 tgatgagaca agaatatggc ttgtcagttt gtgtgacgac acaagtagga tgtaatatcg
     3001 gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg tgatctgact gctggagaaa
     3061 ttgttgcaca gatcatgatg gtccaacatt attttgatga gcgcaatctt ggcgaacgcg
     3121 tttcacatgt cgttgtaatg gggatcggtg agccatttga taattacgac aatgtaatgg
     3181 actttttgca tatcatcaat gatgccaaag gattggcaat tggtgctcgg cacattacag
     3241 tttccactag tggattagca cacaaaatca aggaattcgc taataacggc ttgcaagtca
     3301 atctggctat ttccttgcac gcgccgaata atgaggtgcg aacatcgatc atgcggatca
     3361 accgaagttt cccaattgag aaattgatgg aagctgtgga tgagtattta gagaaaacaa
     3421 accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt aaatgataga ccagagcatg
     3481 cgcaacaatt agcagatcta ttaaaagata agaaaaaatt agcatatgtc aacttgattc
     3541 catataatcc agtcagtgaa catgatcaat attctcgcag tccaaaagct gatgtattga
     3601 gattttatga tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa gaacatggta
     3661 cagatattga tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa acagttgcca
     3721 aataatcgta tcctactcgt tttttcaatt accataaaag gagcagtttt cttaattaag
     3781 gaactgttca acttaaataa gagaaaagat tctatagcga aagctataaa gctttttttg
     3841 acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc ctgcttgatg
     3901 ggggttttag caattattta actgattttc ttatatcctt gctggctttc ttgtgtagca
     3961 tgataagttt ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat ttcataaggc
     4021 acatgtttaa tatcatttgt tgccatggct ttatctaaga ttgcttctaa atcggtcgtg
     4081 acattgagat tcatgtcggt taacgatact ggaagttggt tctttttcat aaacacatag
     4141 attttatcaa acaaatcgaa ctgctgatcc atcatcaata aggtcagtac accataactg
     4201 acagatgctc cgtgaaggta tccctccatt ttttctagaa cagtcgtacc gtaatagaat
     4261 gagtgtgcca tagcagaatt atagttattg ttaactaaaa cagaaaccaa tccggtagta
     4321 acaatgatat ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc ggcactatct
     4381 ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc acatttttcc gatttggatt
     4441 cctaatctat ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga ttcgacttct
     4501 ttggataaag catcgccaat acctgcccat aagtatttat caggtgcttc ggcaataatt
     4561 gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc gtccattacg
     4621 ccttcttcgt tatagatgac acataccgca gtgacgggcg aacagttcga accaatagtg
     4681 ggaaaggtga agactggttt agctagtttt tcaccaatga cttttacagt atcgcaagca
     4741 cggccaccac cgactgcaaa caggacgtct gctttttgga cactttcatg ctggatcaac
     4801 tgttcaatat ttccataagt tgaattaccc ccgtaccaga gactggcgac aacctctatt
     4861 tcctgtgtca aagctacttt tattttgttt tctgcctttg aaagtgcagt cttccctcca
     4921 atcagcacta cttttgtccc atattctttg acgattccat ttgctttttc atacgcatct
     4981 gttccaatgg tataatttgg taagaaaaca ctttgactca tattcatttc cttctttctt
     5041 cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga ctgcggctgt agatggagta
     5101 gaggtgaacc taagacagga taagtgatga ataaggtggc atgaacacct tgaaatcatc
     5161 aataagtatc ctaaaaacga acaagtacaa aaacattgaa aacgacaata atgaattttt
     5221 gttcctctta gtatttctac cgattccctt tgcttttttg taattatcta aaaattctaa
     5281 aaattaagat tattatatga aaacaggttt tatttgtcaa ttcataattg gtttttttta
     5341 aagcaaaaga taatctatat catgatgaac aaacagagtt ttttcctcca attgatggct
     5401 ttcctgatct ttcctatttt gaataaagtg tttctgtata attttttatt ttataagtaa
     5461 gataaataat gaaagaatag agatactgat tggtagctaa agatttttga gcgagaacat
     5521 ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac gtatgataat
     5581 cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt tactgagact
     5641 gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc
     5701 agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta ttggtgcaat
     5761 ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa gctcccgacg
     5821 aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag cttccagagg
     5881 aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt taagtcaaac
     5941 ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc gtgaacatcc
     6001 gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa atgcaaatgg
     6061 ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa attctcaata
     6121 ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa
     6181 ttactt
//
LOCUS       DAFLWZ010000264         5790 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.121, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000264 DAFLWZ010000000
VERSION     DAFLWZ010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.121"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            261..953
                     /locus_tag="L1V38_003115"
     CDS             261..953
                     /locus_tag="L1V38_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1317561.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1280..1777
                     /gene="dfrG"
                     /locus_tag="L1V38_003116"
     CDS             1280..1777
                     /gene="dfrG"
                     /locus_tag="L1V38_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1317562.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1849..3801)
                     /locus_tag="L1V38_003117"
     CDS             complement(1849..3801)
                     /locus_tag="L1V38_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1317563.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3808..4044)
                     /locus_tag="L1V38_003118"
     CDS             complement(3808..4044)
                     /locus_tag="L1V38_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317564.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4446..4736
                     /locus_tag="L1V38_003119"
     CDS             4446..4736
                     /locus_tag="L1V38_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317565.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            5450..5752
                     /locus_tag="L1V38_003120"
                     /pseudo
     CDS             5450..5752
                     /locus_tag="L1V38_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1973 a          917 c         1002 g         1898 t
ORIGIN      
        1 gtaatctatg aaatgaaaag ggttacgttt aataaaactt gcttttttgt ttttgttcac
       61 cataaatatt tatttaagaa agtattaacc tgcatttttc tctataaaaa agatttttta
      121 aatagataaa aaaggaggat taaatgagta tttgatagta tttatattaa aattacatat
      181 gtaatttaaa aacgcttgac attgtgtttg agatcactta cttttagcat gtaaaagtat
      241 tggattaagg agctatgcaa atgaaaaaga aatttattac tggtgggatt gtcgttgcat
      301 ttctatgtct aattggctac acaggcacgc ggtacgcaaa tgaaattatt ttgtggggtg
      361 gagagacaga tattgataca atcaatgaga atctgacaca gcttgatcat acattgacag
      421 ataaagagca agcgattaca gatcttaccg ctcgactagc acaaaaagaa cagacattgc
      481 aagattcaaa ggcagatgtc caagaatacc aaacaaaagt aaatgaatta gaaaaccaaa
      541 aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca attagtcagc aaggatgcac
      601 aactacaaag caaacaaaat gaaatcaatg tcaaactaga tgagatcaac caaaaaaatg
      661 atgaaatcaa tcatctgaat gcagattgga cagcaagact acaagaagca caagcaaaac
      721 tttcagaatt acaaaatact gtaaatggtt tgaatcaaca aatcgcaaca ctgacacaag
      781 aaaaaacaaa tgtagaaact cagttaacag atacacaaaa gaaattagac gaagcaactg
      841 ctgaaaactc aagctggaaa caatatattc aaaagttaga aaaagcaaaa gatgaagtgg
      901 aagatacagc tgataaatct cagcaaattg ttgaagaaca tttgcgtaaa taatctttct
      961 taacaagtaa acctaaatta gtaaagaagc aacagtaatc tatactaagt agttcagttt
     1021 tggagtacaa aatgacaaaa tgtacttcaa aatggactac ttttttcatt ttaacttaca
     1081 taccaaatta catacaaaat gatttataaa atgcaattga aaatgataat tgaatgaaaa
     1141 tttgtgattt tgtggtatta tgataatata acttatagaa aaaattgctt attcaactaa
     1201 cgggcaggat aatgagaaaa ggttttttga tagaaataag aaattagatg gtaaattagt
     1261 taaaaaggct gtgttataaa tgaaagtttc tttgattgct gcgatggata agaatagagt
     1321 gattggcaaa gagaatgaca ttccttggag gattcccaag gactgggaat atgttaaaaa
     1381 tactacaaag ggacatccga taatattagg taggaagaac cttgaatcaa tcggaagagc
     1441 cttacctgac agaagaaata ttattctgac gagagataag gggtttacct ttaatggttg
     1501 tgaaattgtt cattcaatag aagatgtttt tgagttatgt aaaaacgaag aagaaatttt
     1561 tattttcgga ggagaacaga tttataattt gtttttccct tatgttgaga aaatgtacat
     1621 cacaaaaata catcatgaat tcgaaggaga tacttttttt ccagaagtga attatgagga
     1681 atggaatgag gtatttgccc aaaaagggat aaagaatgat aaaaatccgt ataactacta
     1741 ttttcatgta tatgaaagaa aaaacttatt gagttaacgg gtgcgttaat tgaagaagaa
     1801 cagtaaagat aaagcacaag agcttgggat tactccaagc tctttttgtc atttgaaata
     1861 aattatatct ttccaatcaa attgtttatc tgtaatccct aatctttgag caggtgtcaa
     1921 aaccttttta tccgctgatt taaaagggcg acaaaagttg tagtaagttc ttagaattgt
     1981 aatcgcaaat tgagcatact tcggattgaa gttagcgtaa atatagctct tcttatcacc
     2041 acgagctgtt gttaatggtc tttcaagaga tgatatataa cgtcttatct gttgaataaa
     2101 gctattggtc gaatggtcat taacatttaa tagcatcttt gcgatttcgt ttggttccag
     2161 agcagataaa tccgttctac aatcaactga ataaaatcct ttatccttag tggctaatgg
     2221 atgtttgata gggttatcgg catatttgcg atatctttct ccatctttac taatagcctc
     2281 ttcgtggaat tgatgacttg ttagtaattc agttagataa tgagatgcca aagtccgtag
     2341 aaactttgtt ttgaatcctc tgatatctcc ccaatcgagc agttctgctt ttgcttgtcc
     2401 gaattctttt aagcattgtt ttctgctttt cgtcttgtta acttggcaaa taaaatgatg
     2461 tgcatcgctc aaccttaatt ctttcgtgaa tactctataa aaggcgtttc taatagagaa
     2521 gtcatcatca ctaatcattc gccattcgtc ggcattaacc atttgtttaa ttaaccaata
     2581 gtgagcagtt gtagtataag gagcatcaac atttaaacca tcgacaaatc tactcctatt
     2641 agtaattttc cctaattcgt gaagataagc attcctattt tcgctatcgt tagcggatgg
     2701 ttcttgtgga taataagacc aatctaacct atcattttta cgactaaaag tattgagatg
     2761 gtcttctttg aattttcttg tatcttcatt taattcatcc attgaaatat tccaatcata
     2821 ggcaacatca gaacggaaca catatcttga taagacctca gcagatacaa ctatatacgt
     2881 ttgcatatta aggtcttcaa accccgtata tttctttgaa ccttgtcctt tcttacggac
     2941 gttatttagg tagtagtgca tcttgtccgt attaagccac atctcgttaa atttctttgt
     3001 ttgaaggggt tgtgtctcat atcgttctaa aaactccaaa caacgcctat acagccactc
     3061 cagcttatga tagtaggttc caactccaat tcctaaaata tcacaagtac gactgactga
     3121 aacccttcca acaaccatct tagcgaacat tggaagaatg gtgttctttt gttggtgata
     3181 agtagtggtt tcttctcttt ttggtagaac attagtgaac ttcttacacg ccttacattg
     3241 atagcgttga gatttgcccc tacttttccc ccttttgtaa aattgcttcg gctcattgaa
     3301 tggggttgat tcttcttccg agcagccttc tttatgaaat tgataatctg gctcaacatc
     3361 ttggatgcta ttgatttcta taaggcgttt aatttcttca acaacagacc aattagataa
     3421 aggggttact gtacagtttt gcgatacacc tctgccaata ggattgtcat tgcagtacat
     3481 acctttatga cctttatctt tggaactacc agtcatttta tatcgacttg gtttcccttt
     3541 tacatctttg aatttgtgct gttctttccc aaaattacaa caaaacggat tgatgcagta
     3601 attatattga atgggatatt cagaaccgtt ccatttaaaa gacgttggca agaacaacat
     3661 tttgttatac cttgttgcaa atcgttttgg agttaataaa tcatattgtt tagccctatc
     3721 ttttaattct tcgtttgaaa tcggaatttt aacatctaca atttcatctt ccttcgtggc
     3781 taatctttta agcttggtca ttgtctatca acccactcta tctttgatac ccattttttc
     3841 aacaatccgc ttattacttc gcttgttggc aatccattca ataaacttct tatcgtctaa
     3901 aatgttcaat aagaattcat ccactgcttc gctttcagta cgctctgcat attcagcgta
     3961 ttgcttaact atcaccctta cttgctctga tatttcccaa tccacagact tagcgttctt
     4021 attttttggc tcaagaaatt gcataggaaa atgcacccct ttttgcttag taaattgtaa
     4081 ccattttaac acaccaattt gcattcctac aataattatt tcacgttcgc atttttatat
     4141 acattttaac ttacattttg tggtgtaaat taacaacaaa cgttgattta acaataaaaa
     4201 acgagtatca aattcagttg caatttgata ctcatttagg tttacatttt cactttttgt
     4261 actccaaaac tgaactactt aaatctatac tgctgcctct tttttttagt acatgtcctt
     4321 catcttcgca ggaagtgcca atatgatttt aagaaaggta atagacaaaa agtcaaaaag
     4381 ataaaacaga gtttcttctt tacaaaggga atgtatgttc gtataatggt attgaggtga
     4441 aggttatgga gaaaaaatat ggaacagtag ataagatccg tactttgcaa gttagtgcca
     4501 gaccgttgat ccgtttcagt ttaaatgggg tcaattgttt gattgcttcc catagtttga
     4561 acttcctagc tgaagtagac gaagggatga agttagtcgt tacaggttat tataataata
     4621 gaaagcaatt tgttgtgaga tcctatcatg tgttagggaa acccaaaatt gtggtagaat
     4681 atgagaaaag tctataccca agaaaaaagg tccgacaaga tgaaagaata aactagaaaa
     4741 caagcggctg agacaaaaat gtcctagccg cttgttttgg aaagatggat gcagacgatg
     4801 ggatttgaac ccacacgagc atacgctcac aagaacctca atctatatat aactacatgt
     4861 atttaagtat ttgtgatgaa tcactaaact ttccaaactc atttgaggga tattgcttaa
     4921 agattgaaca gatcaattcg aagccctatt agtattcgct caatgggggg atcagaggcc
     4981 ataaaaagag actagtcatt actagtctca ggtagtggaa ttgtaggatt ttaaacgttc
     5041 ctggagagta ccggtatgta actcgaagag gtgattatca tagtcgtaaa agtaaattga
     5101 agaagcctcg cctttcacac gagaacgtcc tggttcgaca gttaaaccta acatttggat
     5161 ttttgagaca aacgaatcta tatcttgttc gtcaatttta aaagcaatat gattgtatgt
     5221 ctttggcagt ttattcgacg aattctgcat tactgcaatc cataggtcct taactaagaa
     5281 aaatttttct ggatataatg aaaatttttt tgttgactat cgtagatttc ttttgcatca
     5341 aataaggtat ttaacaatta agtatttaaa agataacttt taagttatct ttaagtaatg
     5401 cttaaagcta tgttatactc tattaggaaa tataagaagg agtataaaaa tgaacaaaca
     5461 taatagaaaa ataacgaata acaaagaact gatcttgtta ctaataggga tttggggtat
     5521 ctttttactc tttaatatgt atatgccgac tatgagagcg gatgacgtag tttatgcaag
     5581 tagattagat gaacttggct atttgggtgc ttcgatagaa cattataaga catggagttc
     5641 aagaattatt atagaactat tcttaatgtt cttttctaaa cactttatgc tatggaaatt
     5701 attaaattct acgattatgt taggaattgt agtattactt tgcaagtatg ttgagagtat
     5761 aaaatatttt gtgtaaatga aaaaatccat
//
LOCUS       DAFLWZ010000265         4759 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.133, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000265 DAFLWZ010000000
VERSION     DAFLWZ010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.133"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            251..1057
                     /locus_tag="L1V38_003121"
     CDS             251..1057
                     /locus_tag="L1V38_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1317566.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1075..1782
                     /locus_tag="L1V38_003122"
     CDS             1075..1782
                     /locus_tag="L1V38_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1317567.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1779..2750
                     /locus_tag="L1V38_003123"
     CDS             1779..2750
                     /locus_tag="L1V38_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1317568.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2743..3771
                     /gene="vanB"
                     /locus_tag="L1V38_003124"
     CDS             2743..3771
                     /gene="vanB"
                     /locus_tag="L1V38_003124"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1317569.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3777..4385
                     /locus_tag="L1V38_003125"
     CDS             3777..4385
                     /locus_tag="L1V38_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1317570.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4451..4624)
                     /locus_tag="L1V38_003126"
     CDS             complement(4451..4624)
                     /locus_tag="L1V38_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1317571.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1342 a          996 c         1256 g         1165 t
ORIGIN      
        1 tgattcaatt ctaacggagc ttctgtatgt tttgtttttt catgctcaaa agggaccgat
       61 agaatgattt tctatcagtc ctagaaatta tagagccgat tttgaccgac aggtataacc
      121 ctgccggtct ttttttgctg ctacaggaaa actacagact ggctacaggg aaagtacaga
      181 tgcgcttgcc ataataacaa tcgtaccagc cacaaatcgt agttttattg caaaggaggc
      241 attcgatcaa atggaaaaaa gcaactatca ttccaatgcg gatcatcaca aacggcatat
      301 gaaacaatcc gtggaaaagc gggcttttct atgtgcgttc attatttcgt tcacagtctg
      361 cacgctgttt ttggggtgga gactggcttc cgtattggag gcaacacaga taccgcccat
      421 ccctgcaact catacaggca gcagcactga cgtagtggag aatttggagg aaaacgctct
      481 tgccaccgcc aaagaacagg gagatgaaca ggaatggagc ctgattttag tgaacaggca
      541 gaaccccatc cccgcacagt acgatgtgga gcttgagcaa ctatcaaatg gtgagcggat
      601 agatattcgg atttctccct atcttcaaga tttgtttgat gccgcaagaa ctgatggagt
      661 ttacccgatt gtcgcatccg gataccgaac aacagaaaaa cagcaagaaa ttatggatga
      721 aaaaattgcc gaatataagg cgaaaggcta cacctctgca caggctaaag cggaagcaga
      781 aacttgggtg gccgtgccgg gaacgagcga gcatcagctt ggtcttgctg tggatatcaa
      841 tgcggacgga attcattcaa caggcaacga ggtttataga tggctggatg aaaacagcta
      901 tcgttttggt tttattcgtc gctacccacc agacaagaca gagataaccg gtgtgagcaa
      961 cgagccgtgg cattaccgat atgttggcat cgaagctgcc acagagatgt acaaccaagg
     1021 ggtttgcctt gaggaatatt taaaaccaga aaaatgagaa aaggatgtta tgttatggac
     1081 agaaaaagat tgacacagcg tttcccgttc ctgcttccaa tgagacgggc gcagagaaaa
     1141 atgtgctttt atgcgggaat gagatttgac ggctgtcgct atgcgcagac gataggggaa
     1201 aaatcgcttt cccatttgct ctttgaaacg gattgcgcat tatacaacca caataccgga
     1261 tttgacatga tataccagga aaacaaggtg ttcaacttaa agctggcagc aaagacctta
     1321 aacggcttat tgataagacc gggggaaacc ttttctttct ggttgttcct gcatacgcca
     1381 ttgacaatta tccagcgcag aggtcacgaa gtaaaggagt ttccagagcc aaacagtgac
     1441 gagattaaag gggtggatgc aaccatttca gagggctgga ttgatttaaa agtgcgaaac
     1501 gataccgact gcacctacca aatatgggtg accttagatg atgagaaaat catcggtcag
     1561 gtgttcgccg acaaagagcc ccaagcatta tacaaaatta caaatggcag tatccagtat
     1621 gtccgtgaaa gtggcgggat ttatgaatat gcccaggtta aacggatgca agttgcctta
     1681 ggtaccgggg aaataataga ttgcaagctg ctttatacaa acaaatgcaa aatctgttat
     1741 cccctcccgg aaagtgtgga tattcaggag gagaaccaat gagaaaaagt gtgggcatta
     1801 ctgtttttgg atgcgaacag gatgaggcaa atgctttccg cgctttatcg ccggattttc
     1861 atattatccc tacgctgatt agcgatgcga tatcggcaga caacgcaaaa ttggccgctg
     1921 gcaatcaatg cgttagcgta agccataagt ccgaggtttc cgaggcgaca attcttgcgc
     1981 tgagaaaggt cggggtaaaa tacatttcta cccgcagcat cggctgcgat cacattgata
     2041 cgactgccgc cgagagaatg ggaatctcgg ttggcacggt tgcgtattcg ccggacagcg
     2101 ttgcggatta tgctttgatg ctgatgctga tggccatacg gggtgcaaaa cccaccatgc
     2161 acgccgtggc gcaacaagat ttcagattgg atcgtatccg ggggaaagaa ctgggggata
     2221 tgactgtggg agttattgga accggccata tcgggcaagc ggtcgtcaaa aggctgcggg
     2281 gatttggatg ccatgtgctg gcctatgata acagccgaaa aatggatgca gattatgtcc
     2341 agcttgatga gcttctaaaa aacagcgata ttgttacgct ccatgtgccg ctttgtgcgg
     2401 atacccgcca tctgatcggt cagaagcaaa ttggagagat gaagcaaggc gcatttttaa
     2461 tcaacaccgg gcgcggagcg cttgtcgata ccggggcgct ggtggaggcg ttggaaagcg
     2521 gaaagctggg tggtgcggca ctggatgtgt tggagggcga ggatcagttt gtttataccg
     2581 attgctcgca gaaagtgctt gaccatccct ttttgtcgca gcttttaagg atgccgaatg
     2641 tgatcatcac accccatacg gcgtactaca ctgagcgtgt gctgcaggat actacagaaa
     2701 aaacaatcag gaattgtctc aattttgaaa ggagtttaca gcatgaatag aataaaagtc
     2761 gcaatcatct tcggcggttg ctcggaggaa catgatgtgt cggtaaaagc cgcaatagaa
     2821 attgctgcga acattgatac ggaaaaattc gatccgcact acatcggaat tacaaaaaac
     2881 ggtgtatgga agctatgcaa gaagccatgt acggaatggg aagccgacag tctccccgcc
     2941 atactctccc cggataggaa aacgcatggg ctgcttgtca tgaaagaaag cgaatacgaa
     3001 acacggcgta ttgatgtggc tttcccggtt ttgcatggca aatgcgggga ggatggtgcg
     3061 atacaggggc tgtttgtatt gtctggtatc ccctatgtgg gctgtgatat tcaaagctcc
     3121 gcagcttgca tggacaaatc actggcctac attcttacaa aaaatgcggg catcgccgtt
     3181 cccgaatttc aaatgattga taaaggtgac aagccggagg cgggtgcgct tacctaccct
     3241 gtctttgtga agccggcacg gtcaggttcg tcctttggcg taaccaaagt aaacggtacg
     3301 gaagaactta acgctgcgat agaagcggca ggacaatatg atggaaaaat cttaattgag
     3361 caagcgattt cgggctgtga ggtcgggtgt gcggtcatgg ggaacgagga tgatttgatt
     3421 gtcggcgaag tggatcaaat ccggctgagc cacggtatct tccgcatcca tcaggaaaac
     3481 gagccggaaa aaggctcaga aaatgcgatg attacagttc ccgcagacat tccggtcgag
     3541 gaacgaaatc gggtgcagga aacggcaaag aaagtatatc gggtgcttgg atgcagaggg
     3601 cttgcccgtg ttgatctttt tttgcaggag gatggcggca tcgttctaaa tgaggtcaat
     3661 accctgcccg gttttacatc gtacagccgc tacccacgta tgatggccgc cgcaggaatc
     3721 acgcttcctg cactgattga cagcctgatt acattggcgt taaagaggtg ataagtatgg
     3781 aaaatggttt tttgttttta gatgaaatgt tgcatggcgt ccgttgggat gccaagtacg
     3841 ccacatggga taacttcaca ggaaaaccgg tggatgggta tgaggtgaat cgcatcatcg
     3901 gcacaaaggc cgtggcgttt gctctgcgcg aggcacaaat ccatgcggct gcgcttggct
     3961 atggcttgct tttatgggat ggatatcggc caagaactgc ggtggactgc ttcctgcgtt
     4021 gggcagcgca accggaggac aatctcacaa aagaaaaatt ttaccccaat atagagcgag
     4081 ccgagttgat tacaaagggt tatgtggcct cacaatccag ccatagccgt ggaagcgcaa
     4141 ttgatcttac gctctaccac ctggatacag gggaacttgt ttcaatggga agtaacttcg
     4201 attttatgga cgaacggtcg catcatacag caaaagggat aggggatgca gaggcacaaa
     4261 atcgaagatg cttgcgtaaa atcatggaaa gcagcggatt tcagtcttat cgctttgaat
     4321 ggtggcacta taagttgatt gatgagccat accccgatac ctattttaat tttgccgttt
     4381 cataatgaaa gtattggttt tgtatcagat tttggatttg ataaaatcta tgctggtcat
     4441 ggacaatctt ttactggaaa gtggttaaag catcttttgt aatacattgc aaattatagt
     4501 attcaatctg cccagcggca gaaaagaaaa aaaccgctgt tgggcagacc tttcccacgc
     4561 ccattttgta ttttgctggc ggcggttttg agaaatcaag gccgccgttc ttttctggca
     4621 gcaaaaggtg tggcggccca taggaggatg ccgctatgct gttttgctat tgccatgctc
     4681 taatccactt ccaccactca aaaaaagcct tgcccctcca tgaactgaac cccaaaagtt
     4741 gaactattta atggactgt
//
LOCUS       DAFLWZ010000266         3206 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.158, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000266 DAFLWZ010000000
VERSION     DAFLWZ010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.158"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1311
                     /locus_tag="L1V38_003127"
                     /note="aph(2'')-Ia"
     CDS             <1..1311
                     /locus_tag="L1V38_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBN1317572.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKDYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1441..2613)
                     /locus_tag="L1V38_003128"
                     /pseudo
     CDS             complement(1441..2613)
                     /locus_tag="L1V38_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
BASE COUNT         1116 a          413 c          572 g         1105 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaagatt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat gaaaaataat
     1381 aaaggaagtg agtcaagtcc agactcctgt gtaaaatgct atacaatgtt tttaccattt
     1441 ctacttatca aaattgatgt attttcttga agaataaatc cattcatcat gtaggtccat
     1501 aagaacggct ccaattaagc gattggctga tgtttgattg gggaagatgc gaataatctt
     1561 ttctcttctg cgtacttctt gattcagtcg ttcaattaga ttggtactct ttagtcgatt
     1621 gtgggaattt ccttgtacgg tatattgaaa ggcgtcttcg aatccatcat ccaatgatgc
     1681 gcaagctttt gaatattttg gttgatcgat ataatcatga atcaatcgat ttttagcctc
     1741 acgcgctaag ttaatatctg tgaacttaaa aattccttta acagcttctc tgaaagattt
     1801 tgaatttttt ttaggaatgg tggtaaagat atttcttagg aagtgaactt ggcatctttg
     1861 ccaacttacg ttggtgaagg attttctaat ggcagagact aatcctttgt gcgcatcaga
     1921 aataacgagt tccgtacctt gtaaaccgcg ttcttttagg tattcaaaaa atgttgtcca
     1981 ggtctcttcg ctttcgccac tttgaatcat gaagccgata atttcacggt cgccatcttt
     2041 ggttattcca atcgctatat gacagctttt tgagagtact cgattttctt ctcgtacttt
     2101 tatatagagt acatcggtca ttaagtaagg ataatttttt tctgataata aacgattctg
     2161 ccactcgtta accataggtt ctagctgttc tgttaagcta gaaacgaagg acttagagac
     2221 ggatttacca caaagttctt ccacaatttt tgatacttta cgagttgaaa cgcctgatac
     2281 atacatttcc aacattgaag ccatgagggc tttttagttt cgttgataac gttcaaacac
     2341 tgtgggtgaa aaatggccat cacgtgttct gggtactttt aattctagcg tgcctacacg
     2401 tgtcgtaaag ctgcgctcat aatagccatt tcgttgactt tgtcggtttt ctgttcgttc
     2461 atattctttt gcttgaatat attctgttcg ttgattttcc attagttgat taaataccgt
     2521 tgttaaaata tttttagaaa cgtcatcctt tacagaatat tcaataatgc tttgaatctc
     2581 ttcgcttttc agtgtaaaat gtacttgggt catgtaaaag tcctcctggg tatgtttttg
     2641 tcgttaaaaa cattgtaccg taaaaggact gttatatggc ctttttactt ttacacaatt
     2701 atacggactt tatctatata aaggcgctgt cagagttttt tgacttagaa catacattca
     2761 ttcaagagac tttaaacaag ctagcagaac gcccaaaaac ggacacacaa ctcgatttgt
     2821 ttagctatga tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga
     2881 tacgtgtttg tttttctgta ctgtttcctg agtgattagc agaaatataa agattaaaat
     2941 tttaattgat tattaggaag agaaggagaa tgtatcccga aaacttttta gttggcttgg
     3001 actgaacgaa gtgagggaaa ggctactaaa acgtcgaggg gagtgggagc gaagcgcaca
     3061 cttgatcttt tgaacttttt tctaatactt gacttttttt atgtatacag ttactatgta
     3121 tatagtaaca ctttatacaa taggactgta tattaagagg agtgtcttgg ttctgttgca
     3181 aagttttaaa tctactatca aataag
//
LOCUS       DAFLWZ010000267         3206 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.159, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000267 DAFLWZ010000000
VERSION     DAFLWZ010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.159"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            <1..1311
                     /locus_tag="L1V38_003129"
     CDS             <1..1311
                     /locus_tag="L1V38_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBN1317573.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1441..2613)
                     /locus_tag="L1V38_003130"
                     /pseudo
     CDS             complement(1441..2613)
                     /locus_tag="L1V38_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
BASE COUNT         1115 a          413 c          573 g         1105 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat gaaaaataat
     1381 aaaggaagtg agtcaagtcc agactcctgt gtaaaatgct atacaatgtt tttaccattt
     1441 ctacttatca aaattgatgt attttcttga agaataaatc cattcatcat gtaggtccat
     1501 aagaacggct ccaattaagc gattggctga tgtttgattg gggaagatgc gaataatctt
     1561 ttctcttctg cgtacttctt gattcagtcg ttcaattaga ttggtactct ttagtcgatt
     1621 gtgggaattt ccttgtacgg tatattgaaa ggcgtcttcg aatccatcat ccaatgatgc
     1681 gcaagctttt gaatattttg gttgatcgat ataatcatga atcaatcgat ttttagcctc
     1741 acgcgctaag ttaatatctg tgaacttaaa aattccttta acagcttctc tgaaagattt
     1801 tgaatttttt ttaggaatgg tggtaaagat atttcttagg aagtgaactt ggcatctttg
     1861 ccaacttacg ttggtgaagg attttctaat ggcagagact aatcctttgt gcgcatcaga
     1921 aataacgagt tccgtacctt gtaaaccgcg ttcttttagg tattcaaaaa atgttgtcca
     1981 ggtctcttcg ctttcgccac tttgaatcat gaagccgata atttcacggt cgccatcttt
     2041 ggttattcca atcgctatat gacagctttt tgagagtact cgattttctt ctcgtacttt
     2101 tatatagagt acatcggtca ttaagtaagg ataatttttt tctgataata aacgattctg
     2161 ccactcgtta accataggtt ctagctgttc tgttaagcta gaaacgaagg acttagagac
     2221 ggatttacca caaagttctt ccacaatttt tgatacttta cgagttgaaa cgcctgatac
     2281 atacatttcc aacattgaag ccatgagggc tttttagttt cgttgataac gttcaaacac
     2341 tgtgggtgaa aaatggccat cacgtgttct gggtactttt aattctagcg tgcctacacg
     2401 tgtcgtaaag ctgcgctcat aatagccatt tcgttgactt tgtcggtttt ctgttcgttc
     2461 atattctttt gcttgaatat attctgttcg ttgattttcc attagttgat taaataccgt
     2521 tgttaaaata tttttagaaa cgtcatcctt tacagaatat tcaataatgc tttgaatctc
     2581 ttcgcttttc agtgtaaaat gtacttgggt catgtaaaag tcctcctggg tatgtttttg
     2641 tcgttaaaaa cattgtaccg taaaaggact gttatatggc ctttttactt ttacacaatt
     2701 atacggactt tatctatata aaggcgctgt cagagttttt tgacttagaa catacattca
     2761 ttcaagagac tttaaacaag ctagcagaac gcccaaaaac ggacacacaa ctcgatttgt
     2821 ttagctatga tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga
     2881 tacgtgtttg tttttctgta ctgtttcctg agtgattagc agaaatataa agattaaaat
     2941 tttaattgat tattaggaag agaaggagaa tgtatcccga aaacttttta gttggcttgg
     3001 actgaacgaa gtgagggaaa ggctactaaa acgtcgaggg gagtgggagc gaagcgcaca
     3061 cttgatcttt tgaacttttt tctaatactt gacttttttt atgtatacag ttactatgta
     3121 tatagtaaca ctttatacaa taggactgta tattaagagg agtgtcttgg ttctgttgca
     3181 aagttttaaa tctactatca aataag
//
LOCUS       DAFLWZ010000268         2771 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.166, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000268 DAFLWZ010000000
VERSION     DAFLWZ010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.166"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            110..193
                     /locus_tag="L1V38_003131"
     CDS             110..193
                     /locus_tag="L1V38_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1317574.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="L1V38_003132"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="L1V38_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1317575.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="L1V38_003133"
     CDS             complement(1318..2181)
                     /locus_tag="L1V38_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1317576.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="L1V38_003134"
     CDS             complement(2183..2455)
                     /locus_tag="L1V38_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1317577.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="L1V38_003135"
     CDS             complement(2472..2681)
                     /locus_tag="L1V38_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1317578.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DAFLWZ010000269         1122 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-52
            SAMN14852366-rid13729363.guided.217, whole genome shotgun sequence.
ACCESSION   DAFLWZ010000269 DAFLWZ010000000
VERSION     DAFLWZ010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852366
            Sequence Read Archive: SRR11730502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222313.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222313.1
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:54:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,137
            CDSs (total)                      :: 3,072
            Genes (coding)                    :: 2,994
            CDSs (with protein)               :: 2,994
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852366-rid13729363.guided.217"
                     /isolate="VRE-ING-52"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2018"
     gene            24..416
                     /locus_tag="L1V38_003136"
     CDS             24..416
                     /locus_tag="L1V38_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1317579.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1122
                     /gene="aac(6')-Ie"
                     /locus_tag="L1V38_003137"
     CDS             417..>1122
                     /gene="aac(6')-Ie"
                     /locus_tag="L1V38_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HBN1317580.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKK"
BASE COUNT          456 a           88 c          194 g          384 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa ag
//
